row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:13391 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,391 | train | mutant | 3,805,379 | 225 | 3,809,324 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255H | T255H | 1 | 1 | 0 | 0 | 255 | T | H | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,640 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.186138 | 0.112144 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709962,"numValue":0.186138081155765,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709963,"numValue":0.112144375791048,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13392 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,392 | train | mutant | 3,805,379 | 225 | 3,809,324 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255H | T255H | 1 | 1 | 0 | 0 | 255 | T | H | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,234 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.58767 | 0.210371 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183150,"numValue":-0.58767029555909,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183151,"numValue":0.210370944292881,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13393 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,393 | train | mutant | 3,805,380 | 225 | 3,809,325 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255I | T255I | 1 | 1 | 0 | 0 | 255 | T | I | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,641 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.17934 | 0.163046 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709964,"numValue":-0.179339822027011,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709965,"numValue":0.163046377448555,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13394 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,394 | train | mutant | 3,805,380 | 225 | 3,809,325 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255I | T255I | 1 | 1 | 0 | 0 | 255 | T | I | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,235 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.253549 | 0.08288 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183152,"numValue":0.253549073754328,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183153,"numValue":0.0828800475160734,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13395 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,395 | train | mutant | 3,805,381 | 225 | 3,809,326 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255K | T255K | 1 | 1 | 0 | 0 | 255 | T | K | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,642 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.070829 | 0.092606 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709966,"numValue":0.0708294837576848,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709967,"numValue":0.0926055206083028,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13396 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,396 | train | mutant | 3,805,381 | 225 | 3,809,326 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255K | T255K | 1 | 1 | 0 | 0 | 255 | T | K | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,236 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.830826 | 0.370979 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183154,"numValue":-0.830826222876497,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183155,"numValue":0.370978706482464,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13397 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,397 | train | mutant | 3,805,382 | 225 | 3,809,327 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255L | T255L | 1 | 1 | 0 | 0 | 255 | T | L | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,643 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.030287 | 0.085432 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709968,"numValue":-0.0302873309333093,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709969,"numValue":0.0854318172246647,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13398 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,398 | train | mutant | 3,805,382 | 225 | 3,809,327 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255L | T255L | 1 | 1 | 0 | 0 | 255 | T | L | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,237 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.107917 | 0.109237 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183156,"numValue":0.107917076651023,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183157,"numValue":0.109237285854053,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13399 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,399 | train | mutant | 3,805,383 | 225 | 3,809,328 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255M | T255M | 1 | 1 | 0 | 0 | 255 | T | M | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,644 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.045984 | 0.070346 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709970,"numValue":-0.0459840977097193,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709971,"numValue":0.07034649080685,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13400 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,400 | train | mutant | 3,805,383 | 225 | 3,809,328 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255M | T255M | 1 | 1 | 0 | 0 | 255 | T | M | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,238 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.156352 | 0.470571 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183158,"numValue":0.156352331356214,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183159,"numValue":0.470570794700733,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13401 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,401 | train | mutant | 3,805,384 | 225 | 3,809,329 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255N | T255N | 1 | 1 | 0 | 0 | 255 | T | N | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,645 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.115988 | 0.106119 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709972,"numValue":0.115987805531892,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709973,"numValue":0.106119229464451,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13402 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,402 | train | mutant | 3,805,384 | 225 | 3,809,329 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255N | T255N | 1 | 1 | 0 | 0 | 255 | T | N | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,239 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.759186 | 0.11076 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183160,"numValue":-0.759186095323059,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183161,"numValue":0.11075999821654,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13403 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,403 | train | mutant | 3,805,385 | 225 | 3,809,330 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255P | T255P | 1 | 1 | 0 | 0 | 255 | T | P | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,646 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.000551 | 0.191016 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709974,"numValue":1.00055121421414,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709975,"numValue":0.191016240191798,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13404 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,404 | train | mutant | 3,805,385 | 225 | 3,809,330 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255P | T255P | 1 | 1 | 0 | 0 | 255 | T | P | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,240 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.998003 | 0.135451 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183162,"numValue":-0.998002964765608,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183163,"numValue":0.135451379522538,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13406 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,406 | train | mutant | 3,805,386 | 225 | 3,809,331 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255Q | T255Q | 1 | 1 | 0 | 0 | 255 | T | Q | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,241 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.090094 | 0.326309 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183164,"numValue":0.0900936158579436,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183165,"numValue":0.326308737438831,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13407 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,407 | train | mutant | 3,805,387 | 225 | 3,809,332 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255R | T255R | 1 | 1 | 0 | 0 | 255 | T | R | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,648 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.123487 | 0.084618 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709978,"numValue":0.12348659011066,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709979,"numValue":0.0846180536598484,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13408 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,408 | train | mutant | 3,805,387 | 225 | 3,809,332 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255R | T255R | 1 | 1 | 0 | 0 | 255 | T | R | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,242 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.689132 | 0.130504 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183166,"numValue":-0.689131857935098,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183167,"numValue":0.130503698203009,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13409 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,409 | train | mutant | 3,805,388 | 225 | 3,809,333 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255S | T255S | 1 | 1 | 0 | 0 | 255 | T | S | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,649 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.04396 | 0.102997 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709980,"numValue":-0.0439604785509731,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709981,"numValue":0.102997453442679,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13410 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,410 | train | mutant | 3,805,388 | 225 | 3,809,333 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255S | T255S | 1 | 1 | 0 | 0 | 255 | T | S | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,243 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.220323 | 0.077496 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183168,"numValue":-0.220322641799088,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183169,"numValue":0.0774963120454811,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13411 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,411 | train | mutant | 3,805,389 | 225 | 3,809,334 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255V | T255V | 1 | 1 | 0 | 0 | 255 | T | V | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,650 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.079283 | 0.098476 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709982,"numValue":-0.0792827606217956,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709983,"numValue":0.0984758789582171,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13412 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,412 | train | mutant | 3,805,389 | 225 | 3,809,334 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255V | T255V | 1 | 1 | 0 | 0 | 255 | T | V | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,584 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.37552 | 0.08925 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183850,"numValue":0.375520426654822,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183851,"numValue":0.0892499455240641,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13413 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,413 | train | mutant | 3,805,390 | 225 | 3,809,335 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255W | T255W | 1 | 1 | 0 | 0 | 255 | T | W | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,651 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.141729 | 0.141365 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709984,"numValue":0.141728869947935,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709985,"numValue":0.141365032962722,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13414 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,414 | train | mutant | 3,805,390 | 225 | 3,809,335 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255W | T255W | 1 | 1 | 0 | 0 | 255 | T | W | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,585 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.369369 | 0.200633 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183852,"numValue":0.369368945610568,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183853,"numValue":0.200633128316191,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13415 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,415 | train | mutant | 3,805,391 | 225 | 3,809,336 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255Y | T255Y | 1 | 1 | 0 | 0 | 255 | T | Y | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,652 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.111341 | 0.155415 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709986,"numValue":0.111341494815178,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709987,"numValue":0.155414915532149,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13416 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,416 | train | mutant | 3,805,391 | 225 | 3,809,336 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255Y | T255Y | 1 | 1 | 0 | 0 | 255 | T | Y | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,586 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.153578 | 0.176027 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183854,"numValue":-0.153577759580077,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183855,"numValue":0.176026567587003,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13417 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,417 | train | mutant | 4,906,061 | 225 | 4,912,649 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delT255 | delT255 | 1 | 0 | 1 | 0 | 255 | T | - | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,227 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.051281 | 0.525935 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183136,"numValue":-1.0512809492511,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183137,"numValue":0.525935317634342,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13418 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,418 | train | mutant | 4,906,061 | 225 | 4,912,649 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delT255 | delT255 | 1 | 0 | 1 | 0 | 255 | T | - | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,244 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.463178 | 0.312609 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183170,"numValue":-1.46317802498732,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183171,"numValue":0.312608622903601,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13419 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,419 | train | mutant | 3,806,683 | 225 | 3,810,628 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256A | T256A | 1 | 1 | 0 | 0 | 256 | T | A | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,945 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.220703 | 0.079821 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712572,"numValue":0.220703022357703,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712573,"numValue":0.0798205941240002,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13420 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,420 | train | mutant | 3,806,683 | 225 | 3,810,628 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256A | T256A | 1 | 1 | 0 | 0 | 256 | T | A | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,245 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.183596 | 0.091558 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183172,"numValue":-0.183595968592564,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183173,"numValue":0.0915580041277464,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13421 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,421 | train | mutant | 3,806,684 | 225 | 3,810,629 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256C | T256C | 1 | 1 | 0 | 0 | 256 | T | C | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,946 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.008376 | 0.07709 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712574,"numValue":0.0083758075944951,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712575,"numValue":0.0770904438925323,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13423 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,423 | train | mutant | 3,806,685 | 225 | 3,810,630 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256D | T256D | 1 | 1 | 0 | 0 | 256 | T | D | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,947 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.685487 | 0.136502 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712576,"numValue":0.685487312239247,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712577,"numValue":0.136502132731995,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13424 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,424 | train | mutant | 3,806,685 | 225 | 3,810,630 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256D | T256D | 1 | 1 | 0 | 0 | 256 | T | D | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,247 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.026446 | 0.147603 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183176,"numValue":-1.02644578672344,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183177,"numValue":0.147603478746476,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13425 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,425 | train | mutant | 3,806,686 | 225 | 3,810,631 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256E | T256E | 1 | 1 | 0 | 0 | 256 | T | E | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,948 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.236654 | 0.031667 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712578,"numValue":0.236654089052508,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712579,"numValue":0.0316670498884861,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13426 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,426 | train | mutant | 3,806,686 | 225 | 3,810,631 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256E | T256E | 1 | 1 | 0 | 0 | 256 | T | E | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,248 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.35653 | 0.288045 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183178,"numValue":-1.35653039250368,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183179,"numValue":0.28804455203184,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13427 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,427 | train | mutant | 3,806,687 | 225 | 3,810,632 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256F | T256F | 1 | 1 | 0 | 0 | 256 | T | F | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,949 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.49461 | 0.101642 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712580,"numValue":0.494609931676854,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712581,"numValue":0.101641641074428,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13428 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,428 | train | mutant | 3,806,687 | 225 | 3,810,632 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256F | T256F | 1 | 1 | 0 | 0 | 256 | T | F | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,249 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.781248 | 0.074781 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183180,"numValue":-0.781247561333821,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183181,"numValue":0.0747806452158849,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13429 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,429 | train | mutant | 3,806,688 | 225 | 3,810,633 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256G | T256G | 1 | 1 | 0 | 0 | 256 | T | G | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,950 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.484082 | 0.053095 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712582,"numValue":0.484082391274086,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712583,"numValue":0.0530947910046336,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13430 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,430 | train | mutant | 3,806,688 | 225 | 3,810,633 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256G | T256G | 1 | 1 | 0 | 0 | 256 | T | G | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,250 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.776592 | 0.091439 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183182,"numValue":-0.776592296167928,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183183,"numValue":0.0914388097336927,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13431 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,431 | train | mutant | 3,806,689 | 225 | 3,810,634 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256H | T256H | 1 | 1 | 0 | 0 | 256 | T | H | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,951 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.292468 | 0.176194 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712584,"numValue":0.292468255726603,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712585,"numValue":0.176194280078392,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13432 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,432 | train | mutant | 3,806,689 | 225 | 3,810,634 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256H | T256H | 1 | 1 | 0 | 0 | 256 | T | H | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,251 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.867442 | 0.074287 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183184,"numValue":-0.867442136005236,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183185,"numValue":0.0742868716966995,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13433 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,433 | train | mutant | 3,806,690 | 225 | 3,810,635 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256I | T256I | 1 | 1 | 0 | 0 | 256 | T | I | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,952 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.427425 | 0.077077 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712586,"numValue":0.427425164354044,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712587,"numValue":0.0770765691823981,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13434 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,434 | train | mutant | 3,806,690 | 225 | 3,810,635 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256I | T256I | 1 | 1 | 0 | 0 | 256 | T | I | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,252 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.775978 | 0.071861 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183186,"numValue":-0.775977784615674,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183187,"numValue":0.0718608042773823,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13437 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,437 | train | mutant | 3,806,692 | 225 | 3,810,637 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256L | T256L | 1 | 1 | 0 | 0 | 256 | T | L | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,954 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.443864 | 0.053908 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712590,"numValue":0.44386397268393,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712591,"numValue":0.0539083576453401,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13439 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,439 | train | mutant | 3,806,693 | 225 | 3,810,638 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256M | T256M | 1 | 1 | 0 | 0 | 256 | T | M | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,955 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.244626 | 0.0875 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712592,"numValue":0.244625847083405,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712593,"numValue":0.0874998185766309,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13440 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,440 | train | mutant | 3,806,693 | 225 | 3,810,638 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256M | T256M | 1 | 1 | 0 | 0 | 256 | T | M | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,255 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.733899 | 0.116406 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183192,"numValue":-0.733898503339729,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183193,"numValue":0.11640629554394,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13441 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,441 | train | mutant | 3,806,694 | 225 | 3,810,639 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256N | T256N | 1 | 1 | 0 | 0 | 256 | T | N | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,956 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.294279 | 0.070333 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712594,"numValue":0.29427862970536,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712595,"numValue":0.0703327218730948,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13442 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,442 | train | mutant | 3,806,694 | 225 | 3,810,639 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256N | T256N | 1 | 1 | 0 | 0 | 256 | T | N | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,256 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.695443 | 0.076224 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183194,"numValue":-0.695443034005297,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183195,"numValue":0.0762239476950173,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13443 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,443 | train | mutant | 3,806,695 | 225 | 3,810,640 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256P | T256P | 1 | 1 | 0 | 0 | 256 | T | P | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,957 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.62848 | 0.106193 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712596,"numValue":0.628480089285706,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712597,"numValue":0.106193115390437,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13444 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,444 | train | mutant | 3,806,695 | 225 | 3,810,640 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256P | T256P | 1 | 1 | 0 | 0 | 256 | T | P | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,257 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.021187 | 0.076213 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183196,"numValue":-1.02118675182318,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183197,"numValue":0.0762129671700645,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13445 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,445 | train | mutant | 3,806,696 | 225 | 3,810,641 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256Q | T256Q | 1 | 1 | 0 | 0 | 256 | T | Q | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,958 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.197819 | 0.143617 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712598,"numValue":0.197819304268831,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712599,"numValue":0.143617225874162,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13446 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,446 | train | mutant | 3,806,696 | 225 | 3,810,641 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256Q | T256Q | 1 | 1 | 0 | 0 | 256 | T | Q | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,258 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.848458 | 0.14391 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183198,"numValue":-0.848457604051922,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183199,"numValue":0.14391012348026,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13447 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,447 | train | mutant | 3,806,697 | 225 | 3,810,642 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256R | T256R | 1 | 1 | 0 | 0 | 256 | T | R | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,959 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.299704 | 0.043487 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712600,"numValue":0.299703607609406,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712601,"numValue":0.0434865531114328,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13448 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,448 | train | mutant | 3,806,697 | 225 | 3,810,642 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256R | T256R | 1 | 1 | 0 | 0 | 256 | T | R | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,259 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.808288 | 0.063378 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183200,"numValue":-0.808288456703649,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183201,"numValue":0.0633783567081855,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13451 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,451 | train | mutant | 3,806,699 | 225 | 3,810,644 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256V | T256V | 1 | 1 | 0 | 0 | 256 | T | V | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,961 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.182296 | 0.083101 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712604,"numValue":0.182296361841476,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712605,"numValue":0.0831007027564314,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13452 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,452 | train | mutant | 3,806,699 | 225 | 3,810,644 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256V | T256V | 1 | 1 | 0 | 0 | 256 | T | V | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,581 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.781647 | 0.093231 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183844,"numValue":-0.781646679545151,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183845,"numValue":0.0932312610787181,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13453 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,453 | train | mutant | 3,806,700 | 225 | 3,810,645 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256W | T256W | 1 | 1 | 0 | 0 | 256 | T | W | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,962 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.462727 | 0.093485 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712606,"numValue":0.462727490698222,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712607,"numValue":0.0934849499241231,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13454 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,454 | train | mutant | 3,806,700 | 225 | 3,810,645 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256W | T256W | 1 | 1 | 0 | 0 | 256 | T | W | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,582 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.876449 | 0.143417 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183846,"numValue":-0.876449349227452,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183847,"numValue":0.143416875116616,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13455 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,455 | train | mutant | 3,806,701 | 225 | 3,810,646 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256Y | T256Y | 1 | 1 | 0 | 0 | 256 | T | Y | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,859,963 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.4329 | 0.086064 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9712608,"numValue":0.432900070959521,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9712609,"numValue":0.0860641292883345,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13456 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,456 | train | mutant | 3,806,701 | 225 | 3,810,646 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T256Y | T256Y | 1 | 1 | 0 | 0 | 256 | T | Y | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,583 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.797459 | 0.071624 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183848,"numValue":-0.79745879461534,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183849,"numValue":0.0716236885936173,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16920,"numValue":9.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13458 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,458 | train | mutant | 3,807,992 | 225 | 3,811,937 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257A | S257A | 1 | 1 | 0 | 0 | 257 | S | A | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,262 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.161992 | 0.077195 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183206,"numValue":-0.161992183592881,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183207,"numValue":0.0771949682476438,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13459 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,459 | train | mutant | 3,807,993 | 225 | 3,811,938 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257C | S257C | 1 | 1 | 0 | 0 | 257 | S | C | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,257 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.218332 | 0.074125 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715196,"numValue":0.21833183101993,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715197,"numValue":0.074125396956526,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13460 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,460 | train | mutant | 3,807,993 | 225 | 3,811,938 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257C | S257C | 1 | 1 | 0 | 0 | 257 | S | C | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,263 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.306048 | 0.07606 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183208,"numValue":-0.306047918382299,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183209,"numValue":0.076059629708929,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13461 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,461 | train | mutant | 3,807,994 | 225 | 3,811,939 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257D | S257D | 1 | 1 | 0 | 0 | 257 | S | D | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,258 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.667382 | 0.088823 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715198,"numValue":0.667382447171051,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715199,"numValue":0.0888226309652063,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13462 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,462 | train | mutant | 3,807,994 | 225 | 3,811,939 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257D | S257D | 1 | 1 | 0 | 0 | 257 | S | D | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,264 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.753357 | 0.112646 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183210,"numValue":-0.753356709677423,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183211,"numValue":0.112645545316601,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13463 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,463 | train | mutant | 3,807,995 | 225 | 3,811,940 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257E | S257E | 1 | 1 | 0 | 0 | 257 | S | E | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,259 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.581619 | 0.079556 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715200,"numValue":0.581618734051777,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715201,"numValue":0.0795555849098761,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13464 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,464 | train | mutant | 3,807,995 | 225 | 3,811,940 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257E | S257E | 1 | 1 | 0 | 0 | 257 | S | E | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,265 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.556002 | 0.314555 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183212,"numValue":-0.556002143318902,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183213,"numValue":0.314554722028946,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13466 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,466 | train | mutant | 3,807,996 | 225 | 3,811,941 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257F | S257F | 1 | 1 | 0 | 0 | 257 | S | F | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,266 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.027082 | 0.085147 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183214,"numValue":-1.02708194104952,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183215,"numValue":0.0851472872117787,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13467 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,467 | train | mutant | 3,807,997 | 225 | 3,811,942 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257G | S257G | 1 | 1 | 0 | 0 | 257 | S | G | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,261 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.528882 | 0.075612 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715204,"numValue":0.52888236743254,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715205,"numValue":0.0756115280742201,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13468 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,468 | train | mutant | 3,807,997 | 225 | 3,811,942 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257G | S257G | 1 | 1 | 0 | 0 | 257 | S | G | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,267 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.579456 | 0.11588 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183216,"numValue":-0.57945590806608,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183217,"numValue":0.115879548622288,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13469 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,469 | train | mutant | 3,807,998 | 225 | 3,811,943 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257H | S257H | 1 | 1 | 0 | 0 | 257 | S | H | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,262 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.247854 | 0.076093 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715206,"numValue":0.247854468500736,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715207,"numValue":0.0760927183254901,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13470 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,470 | train | mutant | 3,807,998 | 225 | 3,811,943 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257H | S257H | 1 | 1 | 0 | 0 | 257 | S | H | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,268 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.503142 | 0.077867 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183218,"numValue":-0.503142214471828,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183219,"numValue":0.0778674537888884,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13471 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,471 | train | mutant | 3,807,999 | 225 | 3,811,944 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257I | S257I | 1 | 1 | 0 | 0 | 257 | S | I | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,263 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.827935 | 0.113901 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715208,"numValue":0.827935168991167,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715209,"numValue":0.113901152653529,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13472 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,472 | train | mutant | 3,807,999 | 225 | 3,811,944 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257I | S257I | 1 | 1 | 0 | 0 | 257 | S | I | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,269 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.740352 | 0.0743 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183220,"numValue":-0.74035210795823,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183221,"numValue":0.0742999687576216,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13473 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,473 | train | mutant | 3,808,000 | 225 | 3,811,945 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257K | S257K | 1 | 1 | 0 | 0 | 257 | S | K | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,264 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.566251 | 0.169499 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715210,"numValue":0.566251451693592,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715211,"numValue":0.169499411733671,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13474 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,474 | train | mutant | 3,808,000 | 225 | 3,811,945 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257K | S257K | 1 | 1 | 0 | 0 | 257 | S | K | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,270 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.859199 | 0.181855 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183222,"numValue":-0.859199342371586,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183223,"numValue":0.181855077973404,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13475 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,475 | train | mutant | 3,808,001 | 225 | 3,811,946 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257L | S257L | 1 | 1 | 0 | 0 | 257 | S | L | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,265 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.640263 | 0.065681 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715212,"numValue":0.640262880228189,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715213,"numValue":0.0656813451429975,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13476 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,476 | train | mutant | 3,808,001 | 225 | 3,811,946 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257L | S257L | 1 | 1 | 0 | 0 | 257 | S | L | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,271 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.13746 | 0.079338 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183224,"numValue":-1.13745976925628,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183225,"numValue":0.079338374675348,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13477 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,477 | train | mutant | 3,808,002 | 225 | 3,811,947 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257M | S257M | 1 | 1 | 0 | 0 | 257 | S | M | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,266 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.349885 | 0.09433 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715214,"numValue":0.349884900783568,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715215,"numValue":0.0943297881134613,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13478 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,478 | train | mutant | 3,808,002 | 225 | 3,811,947 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257M | S257M | 1 | 1 | 0 | 0 | 257 | S | M | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,272 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.363203 | 0.098419 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183226,"numValue":-0.363203142142462,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183227,"numValue":0.0984189225667822,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13479 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,479 | train | mutant | 3,808,003 | 225 | 3,811,948 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257N | S257N | 1 | 1 | 0 | 0 | 257 | S | N | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,267 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.492902 | 0.09711 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715216,"numValue":0.49290228456656,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715217,"numValue":0.0971097376390888,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13480 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,480 | train | mutant | 3,808,003 | 225 | 3,811,948 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257N | S257N | 1 | 1 | 0 | 0 | 257 | S | N | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,273 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.692969 | 0.089613 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183228,"numValue":-0.692968676146894,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183229,"numValue":0.0896132576757659,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13481 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,481 | train | mutant | 3,808,004 | 225 | 3,811,949 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257P | S257P | 1 | 1 | 0 | 0 | 257 | S | P | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,268 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.887657 | 0.050445 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715218,"numValue":0.887657446536561,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715219,"numValue":0.0504454145418715,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13482 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,482 | train | mutant | 3,808,004 | 225 | 3,811,949 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257P | S257P | 1 | 1 | 0 | 0 | 257 | S | P | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,274 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.808044 | 0.088927 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183230,"numValue":-0.808043861531872,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183231,"numValue":0.0889270544352324,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13483 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,483 | train | mutant | 3,808,005 | 225 | 3,811,950 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257Q | S257Q | 1 | 1 | 0 | 0 | 257 | S | Q | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,269 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.163245 | 0.061677 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715220,"numValue":0.163244573125435,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715221,"numValue":0.0616765332809949,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13484 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,484 | train | mutant | 3,808,005 | 225 | 3,811,950 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257Q | S257Q | 1 | 1 | 0 | 0 | 257 | S | Q | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,275 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.409804 | 0.112913 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183232,"numValue":-0.409803535214223,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183233,"numValue":0.112912817659475,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13485 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,485 | train | mutant | 3,808,006 | 225 | 3,811,951 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257R | S257R | 1 | 1 | 0 | 0 | 257 | S | R | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,270 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.540846 | 0.11467 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715222,"numValue":0.540845687146055,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715223,"numValue":0.114670338226296,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13486 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,486 | train | mutant | 3,808,006 | 225 | 3,811,951 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257R | S257R | 1 | 1 | 0 | 0 | 257 | S | R | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,276 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.851583 | 0.06939 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183234,"numValue":-0.851583393488508,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183235,"numValue":0.0693896291798348,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13487 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,487 | train | mutant | 3,808,007 | 225 | 3,811,952 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257T | S257T | 1 | 1 | 0 | 0 | 257 | S | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,271 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.136531 | 0.144725 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715224,"numValue":-0.136531063696922,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715225,"numValue":0.144724817089966,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13488 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,488 | train | mutant | 3,808,007 | 225 | 3,811,952 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257T | S257T | 1 | 1 | 0 | 0 | 257 | S | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,577 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.149182 | 0.057922 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183836,"numValue":0.149181571147856,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183837,"numValue":0.0579216962294823,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13489 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,489 | train | mutant | 3,808,008 | 225 | 3,811,953 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257V | S257V | 1 | 1 | 0 | 0 | 257 | S | V | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,272 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.324376 | 0.110815 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715226,"numValue":0.324376454378793,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715227,"numValue":0.110814958005191,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13490 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,490 | train | mutant | 3,808,008 | 225 | 3,811,953 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257V | S257V | 1 | 1 | 0 | 0 | 257 | S | V | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,578 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.794928 | 0.072439 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183838,"numValue":-0.794928499734894,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183839,"numValue":0.0724388970885429,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13492 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,492 | train | mutant | 3,808,009 | 225 | 3,811,954 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257W | S257W | 1 | 1 | 0 | 0 | 257 | S | W | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,579 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.639217 | 0.110201 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183840,"numValue":-0.639216937707995,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183841,"numValue":0.110200707565136,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13493 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,493 | train | mutant | 3,808,010 | 225 | 3,811,955 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257Y | S257Y | 1 | 1 | 0 | 0 | 257 | S | Y | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,861,274 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.609169 | 0.106373 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9715230,"numValue":0.609169272222076,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9715231,"numValue":0.106372721431355,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13494 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,494 | train | mutant | 3,808,010 | 225 | 3,811,955 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | S257Y | S257Y | 1 | 1 | 0 | 0 | 257 | S | Y | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,580 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.700632 | 0.09935 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183842,"numValue":-0.700631650321618,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183843,"numValue":0.0993503575312634,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13495 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,495 | train | mutant | 4,906,062 | 225 | 4,912,650 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delS257 | delS257 | 1 | 0 | 1 | 0 | 257 | S | - | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,261 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.25053 | 0.176901 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183204,"numValue":-1.25053037228519,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183205,"numValue":0.176901190270206,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16921,"numValue":8.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13496 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,496 | train | mutant | 3,809,302 | 225 | 3,813,247 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258A | W258A | 1 | 1 | 0 | 0 | 258 | W | A | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,567 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.187701 | 0.051816 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717816,"numValue":0.1877012084751,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717817,"numValue":0.0518158454307509,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13497 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,497 | train | mutant | 3,809,302 | 225 | 3,813,247 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258A | W258A | 1 | 1 | 0 | 0 | 258 | W | A | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,278 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.412184 | 0.110488 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183238,"numValue":-0.412184240334442,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183239,"numValue":0.110487951732381,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13498 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,498 | train | mutant | 3,809,303 | 225 | 3,813,248 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258C | W258C | 1 | 1 | 0 | 0 | 258 | W | C | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,568 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.184983 | 0.077502 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717818,"numValue":0.184983115625553,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717819,"numValue":0.0775017744719003,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13499 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,499 | train | mutant | 3,809,303 | 225 | 3,813,248 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258C | W258C | 1 | 1 | 0 | 0 | 258 | W | C | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,279 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.679062 | 0.085846 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183240,"numValue":-0.679061920863094,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183241,"numValue":0.0858463806337786,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13500 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,500 | train | mutant | 3,809,304 | 225 | 3,813,249 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | W258D | W258D | 1 | 1 | 0 | 0 | 258 | W | D | 9 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,862,569 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.196618 | 0.049846 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9717820,"numValue":0.196617572075749,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9717821,"numValue":0.0498457007326929,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16922,"numValue":9.0,"position":258,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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