row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:5463262 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,262 | train | mutant | 5,054,741 | 5,060,731 | 5,061,407 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179C | Q179C | 1 | 1 | 0 | 0 | 179 | Q | C | 5 | CONSERVATION | null | false | false | null | null | 5,441,249 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.486535 | 0.077571 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875180,"numValue":-0.48653462549272,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875181,"numValue":0.0775708723033569,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463263 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,263 | train | mutant | 5,054,742 | 5,060,731 | 5,061,408 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179D | Q179D | 1 | 1 | 0 | 0 | 179 | Q | D | 5 | CONSERVATION | null | false | false | null | null | 5,441,250 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.173805 | 0.100797 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875182,"numValue":-0.173805280636045,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875183,"numValue":0.100797370775415,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463264 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,264 | train | mutant | 5,054,743 | 5,060,731 | 5,061,409 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179E | Q179E | 1 | 1 | 0 | 0 | 179 | Q | E | 5 | CONSERVATION | null | false | false | null | null | 5,441,251 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.148433 | 0.078823 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875184,"numValue":-0.148433071852756,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875185,"numValue":0.0788231059551011,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463267 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,267 | train | mutant | 5,054,746 | 5,060,731 | 5,061,412 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179H | Q179H | 1 | 1 | 0 | 0 | 179 | Q | H | 5 | CONSERVATION | null | false | false | null | null | 5,441,254 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.695441 | 0.374066 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875190,"numValue":-0.695441012040769,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875191,"numValue":0.374066064215842,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463268 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,268 | train | mutant | 5,054,747 | 5,060,731 | 5,061,413 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179I | Q179I | 1 | 1 | 0 | 0 | 179 | Q | I | 5 | CONSERVATION | null | false | false | null | null | 5,441,255 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.178386 | 0.164073 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875192,"numValue":-0.178385673343746,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875193,"numValue":0.164072999609734,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463269 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,269 | train | mutant | 5,054,748 | 5,060,731 | 5,061,414 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179K | Q179K | 1 | 1 | 0 | 0 | 179 | Q | K | 5 | CONSERVATION | null | false | false | null | null | 5,441,256 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.059289 | 0.08915 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875194,"numValue":-0.0592890782310834,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875195,"numValue":0.0891500590984946,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463270 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,270 | train | mutant | 5,054,749 | 5,060,731 | 5,061,415 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179L | Q179L | 1 | 1 | 0 | 0 | 179 | Q | L | 5 | CONSERVATION | null | false | false | null | null | 5,441,257 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.600437 | 0.078025 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875196,"numValue":-0.600436554713394,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875197,"numValue":0.0780246976639135,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463271 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,271 | train | mutant | 5,054,750 | 5,060,731 | 5,061,416 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179M | Q179M | 1 | 1 | 0 | 0 | 179 | Q | M | 5 | CONSERVATION | null | false | false | null | null | 5,441,258 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.252013 | 0.109199 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875198,"numValue":-0.252012900311494,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875199,"numValue":0.109198566951292,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463272 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,272 | train | mutant | 5,054,751 | 5,060,731 | 5,061,417 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179N | Q179N | 1 | 1 | 0 | 0 | 179 | Q | N | 5 | CONSERVATION | null | false | false | null | null | 5,441,259 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.528702 | 0.271126 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875200,"numValue":-0.528701692667078,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875201,"numValue":0.271125728555547,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463273 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,273 | train | mutant | 5,054,752 | 5,060,731 | 5,061,418 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179P | Q179P | 1 | 1 | 0 | 0 | 179 | Q | P | 5 | CONSERVATION | null | false | false | null | null | 5,441,260 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.47961 | 0.085025 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875202,"numValue":-0.479609766375391,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875203,"numValue":0.0850248963880884,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463274 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,274 | train | mutant | 5,055,053 | 5,060,731 | 5,061,719 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179R | Q179R | 1 | 1 | 0 | 0 | 179 | Q | R | 5 | CONSERVATION | null | false | false | null | null | 5,441,561 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.025874 | 0.045357 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875804,"numValue":-0.0258740471814289,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875805,"numValue":0.0453574505204738,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463275 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,275 | train | mutant | 5,055,054 | 5,060,731 | 5,061,720 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179S | Q179S | 1 | 1 | 0 | 0 | 179 | Q | S | 5 | CONSERVATION | null | false | false | null | null | 5,441,562 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.32163 | 0.065505 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875806,"numValue":-0.321629761698589,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875807,"numValue":0.0655054896555687,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463276 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,276 | train | mutant | 5,055,055 | 5,060,731 | 5,061,721 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179T | Q179T | 1 | 1 | 0 | 0 | 179 | Q | T | 5 | CONSERVATION | null | false | false | null | null | 5,441,563 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.323085 | 0.080511 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875808,"numValue":-0.323085220747442,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875809,"numValue":0.080511096231184,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463277 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,277 | train | mutant | 5,055,056 | 5,060,731 | 5,061,722 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179V | Q179V | 1 | 1 | 0 | 0 | 179 | Q | V | 5 | CONSERVATION | null | false | false | null | null | 5,441,564 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.480684 | 0.084495 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875810,"numValue":-0.480684058091306,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875811,"numValue":0.0844951567965663,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463278 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,278 | train | mutant | 5,055,057 | 5,060,731 | 5,061,723 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q179W | Q179W | 1 | 1 | 0 | 0 | 179 | Q | W | 5 | CONSERVATION | null | false | false | null | null | 5,441,565 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.801398 | 0.12684 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875812,"numValue":-0.801397613554106,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875813,"numValue":0.126839718976882,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462412,"numValue":5.0,"position":179,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463280 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,280 | train | mutant | 5,054,753 | 5,060,731 | 5,061,419 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delA180 | delA180 | 1 | 0 | 1 | 0 | 180 | A | - | 8 | CONSERVATION | null | false | false | null | null | 5,441,261 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.714711 | 0.458976 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875204,"numValue":-0.714710968058082,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875205,"numValue":0.458976355015551,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463281 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,281 | train | mutant | 5,055,034 | 5,060,731 | 5,061,700 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180C | A180C | 1 | 1 | 0 | 0 | 180 | A | C | 8 | CONSERVATION | null | false | false | null | null | 5,441,542 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.62913 | 0.132333 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875766,"numValue":-0.629130282451698,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875767,"numValue":0.132332550940029,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463282 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,282 | train | mutant | 5,055,035 | 5,060,731 | 5,061,701 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180D | A180D | 1 | 1 | 0 | 0 | 180 | A | D | 8 | CONSERVATION | null | false | false | null | null | 5,441,543 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.020857 | 0.269071 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875768,"numValue":-1.02085703591321,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875769,"numValue":0.269071319632272,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463286 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,286 | train | mutant | 5,055,039 | 5,060,731 | 5,061,705 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180H | A180H | 1 | 1 | 0 | 0 | 180 | A | H | 8 | CONSERVATION | null | false | false | null | null | 5,441,547 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.766434 | 0.327737 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875776,"numValue":-0.766434034348157,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875777,"numValue":0.327737058387397,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463287 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,287 | train | mutant | 5,055,040 | 5,060,731 | 5,061,706 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180I | A180I | 1 | 1 | 0 | 0 | 180 | A | I | 8 | CONSERVATION | null | false | false | null | null | 5,441,548 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.371677 | 0.189223 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875778,"numValue":-0.371676649430603,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875779,"numValue":0.189223467329825,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463288 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,288 | train | mutant | 5,055,041 | 5,060,731 | 5,061,707 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180K | A180K | 1 | 1 | 0 | 0 | 180 | A | K | 8 | CONSERVATION | null | false | false | null | null | 5,441,549 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.44564 | 0.184672 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875780,"numValue":-0.445639903814307,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875781,"numValue":0.184671678133876,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463289 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,289 | train | mutant | 5,055,042 | 5,060,731 | 5,061,708 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180L | A180L | 1 | 1 | 0 | 0 | 180 | A | L | 8 | CONSERVATION | null | false | false | null | null | 5,441,550 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.032542 | 0.05069 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875782,"numValue":0.0325422408584884,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875783,"numValue":0.0506899815082766,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463291 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,291 | train | mutant | 5,055,044 | 5,060,731 | 5,061,710 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180N | A180N | 1 | 1 | 0 | 0 | 180 | A | N | 8 | CONSERVATION | null | false | false | null | null | 5,441,552 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.277893 | 0.224333 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875786,"numValue":-0.277892821428372,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875787,"numValue":0.224332937215132,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463292 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,292 | train | mutant | 5,055,045 | 5,060,731 | 5,061,711 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180P | A180P | 1 | 1 | 0 | 0 | 180 | A | P | 8 | CONSERVATION | null | false | false | null | null | 5,441,553 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.658297 | 0.112481 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875788,"numValue":-0.658296925840767,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875789,"numValue":0.112480692230523,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463293 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,293 | train | mutant | 5,055,046 | 5,060,731 | 5,061,712 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180Q | A180Q | 1 | 1 | 0 | 0 | 180 | A | Q | 8 | CONSERVATION | null | false | false | null | null | 5,441,554 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.710651 | 0.144623 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875790,"numValue":-0.710651376344481,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875791,"numValue":0.144622867007238,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463294 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,294 | train | mutant | 5,055,047 | 5,060,731 | 5,061,713 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180R | A180R | 1 | 1 | 0 | 0 | 180 | A | R | 8 | CONSERVATION | null | false | false | null | null | 5,441,555 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.622145 | 0.083813 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875792,"numValue":-0.622144960107519,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875793,"numValue":0.0838128225776202,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463295 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,295 | train | mutant | 5,055,048 | 5,060,731 | 5,061,714 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180S | A180S | 1 | 1 | 0 | 0 | 180 | A | S | 8 | CONSERVATION | null | false | false | null | null | 5,441,556 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.54418 | 0.085709 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875794,"numValue":-0.544180151046335,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875795,"numValue":0.0857086352437723,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463296 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,296 | train | mutant | 5,055,049 | 5,060,731 | 5,061,715 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180T | A180T | 1 | 1 | 0 | 0 | 180 | A | T | 8 | CONSERVATION | null | false | false | null | null | 5,441,557 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.45195 | 0.11911 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875796,"numValue":-0.451950042817478,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875797,"numValue":0.119109683773174,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463297 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,297 | train | mutant | 5,055,050 | 5,060,731 | 5,061,716 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180V | A180V | 1 | 1 | 0 | 0 | 180 | A | V | 8 | CONSERVATION | null | false | false | null | null | 5,441,558 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.484102 | 0.05458 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875798,"numValue":-0.484101986204233,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875799,"numValue":0.0545804804974968,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463298 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,298 | train | mutant | 5,055,051 | 5,060,731 | 5,061,717 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180W | A180W | 1 | 1 | 0 | 0 | 180 | A | W | 8 | CONSERVATION | null | false | false | null | null | 5,441,559 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.490592 | 0.099172 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875800,"numValue":-0.490591918709841,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875801,"numValue":0.0991718868341643,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463299 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,299 | train | mutant | 5,055,052 | 5,060,731 | 5,061,718 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A180Y | A180Y | 1 | 1 | 0 | 0 | 180 | A | Y | 8 | CONSERVATION | null | false | false | null | null | 5,441,560 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.238793 | 0.131044 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875802,"numValue":-0.238792714723865,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875803,"numValue":0.131043669038853,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462413,"numValue":8.0,"position":180,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463300 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,300 | train | mutant | 5,054,754 | 5,060,731 | 5,061,420 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delL181 | delL181 | 1 | 0 | 1 | 0 | 181 | L | - | 9 | CONSERVATION | null | false | false | null | null | 5,441,262 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.683309 | 0.220119 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875206,"numValue":-0.683308845300812,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875207,"numValue":0.220118899307498,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463301 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,301 | train | mutant | 5,054,755 | 5,060,731 | 5,061,421 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181A | L181A | 1 | 1 | 0 | 0 | 181 | L | A | 9 | CONSERVATION | null | false | false | null | null | 5,441,263 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.732654 | 0.14039 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875208,"numValue":-0.732653733899551,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875209,"numValue":0.140390377280639,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463302 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,302 | train | mutant | 5,054,756 | 5,060,731 | 5,061,422 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181C | L181C | 1 | 1 | 0 | 0 | 181 | L | C | 9 | CONSERVATION | null | false | false | null | null | 5,441,264 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.688261 | 0.213199 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875210,"numValue":-0.688260700578535,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875211,"numValue":0.213198892571626,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463303 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,303 | train | mutant | 5,054,757 | 5,060,731 | 5,061,423 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181D | L181D | 1 | 1 | 0 | 0 | 181 | L | D | 9 | CONSERVATION | null | false | false | null | null | 5,441,265 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.008653 | 0.432759 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875212,"numValue":-1.00865272192263,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875213,"numValue":0.43275900184598,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463304 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,304 | train | mutant | 5,054,758 | 5,060,731 | 5,061,424 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181E | L181E | 1 | 1 | 0 | 0 | 181 | L | E | 9 | CONSERVATION | null | false | false | null | null | 5,441,266 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.885955 | 0.190138 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875214,"numValue":-0.885955051943626,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875215,"numValue":0.19013788584613,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463305 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,305 | train | mutant | 5,054,759 | 5,060,731 | 5,061,425 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181F | L181F | 1 | 1 | 0 | 0 | 181 | L | F | 9 | CONSERVATION | null | false | false | null | null | 5,441,267 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.477146 | 0.166111 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875216,"numValue":-0.477146033537298,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875217,"numValue":0.166111319057648,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463306 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,306 | train | mutant | 5,054,760 | 5,060,731 | 5,061,426 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181G | L181G | 1 | 1 | 0 | 0 | 181 | L | G | 9 | CONSERVATION | null | false | false | null | null | 5,441,268 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.763622 | 0.101455 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875218,"numValue":-0.763621632363469,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875219,"numValue":0.101454868462952,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463307 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,307 | train | mutant | 5,054,761 | 5,060,731 | 5,061,427 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181H | L181H | 1 | 1 | 0 | 0 | 181 | L | H | 9 | CONSERVATION | null | false | false | null | null | 5,441,269 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.333965 | 0.157965 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875220,"numValue":-0.333965281529905,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875221,"numValue":0.157964809061184,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463308 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,308 | train | mutant | 5,054,762 | 5,060,731 | 5,061,428 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181I | L181I | 1 | 1 | 0 | 0 | 181 | L | I | 9 | CONSERVATION | null | false | false | null | null | 5,441,270 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.001128 | 0.13433 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875222,"numValue":0.0011281786889472,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875223,"numValue":0.13433032746392,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463309 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,309 | train | mutant | 5,054,763 | 5,060,731 | 5,061,429 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181K | L181K | 1 | 1 | 0 | 0 | 181 | L | K | 9 | CONSERVATION | null | false | false | null | null | 5,441,271 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.080378 | 0.522313 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875224,"numValue":-0.0803784219065868,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875225,"numValue":0.522312702465217,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463310 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,310 | train | mutant | 5,055,024 | 5,060,731 | 5,061,690 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181M | L181M | 1 | 1 | 0 | 0 | 181 | L | M | 9 | CONSERVATION | null | false | false | null | null | 5,441,532 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.448761 | 0.179944 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875746,"numValue":-0.448760878951439,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875747,"numValue":0.179943926262956,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463311 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,311 | train | mutant | 5,055,025 | 5,060,731 | 5,061,691 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181N | L181N | 1 | 1 | 0 | 0 | 181 | L | N | 9 | CONSERVATION | null | false | false | null | null | 5,441,533 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.539781 | 0.496104 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875748,"numValue":-0.539780828783561,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875749,"numValue":0.496104351740193,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463312 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,312 | train | mutant | 5,055,026 | 5,060,731 | 5,061,692 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181P | L181P | 1 | 1 | 0 | 0 | 181 | L | P | 9 | CONSERVATION | null | false | false | null | null | 5,441,534 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.568949 | 0.13519 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875750,"numValue":-0.568948876809368,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875751,"numValue":0.135190028994575,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463313 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,313 | train | mutant | 5,055,027 | 5,060,731 | 5,061,693 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181Q | L181Q | 1 | 1 | 0 | 0 | 181 | L | Q | 9 | CONSERVATION | null | false | false | null | null | 5,441,535 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.876362 | 0.445138 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875752,"numValue":-0.876361927001986,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875753,"numValue":0.445137873874794,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463315 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,315 | train | mutant | 5,055,029 | 5,060,731 | 5,061,695 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181S | L181S | 1 | 1 | 0 | 0 | 181 | L | S | 9 | CONSERVATION | null | false | false | null | null | 5,441,537 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.837529 | 0.16142 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875756,"numValue":-0.837529499366716,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875757,"numValue":0.161420406977533,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463316 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,316 | train | mutant | 5,055,030 | 5,060,731 | 5,061,696 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181T | L181T | 1 | 1 | 0 | 0 | 181 | L | T | 9 | CONSERVATION | null | false | false | null | null | 5,441,538 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.983931 | 0.604518 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875758,"numValue":-0.983930668407565,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875759,"numValue":0.604517535213684,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463317 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,317 | train | mutant | 5,055,031 | 5,060,731 | 5,061,697 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181V | L181V | 1 | 1 | 0 | 0 | 181 | L | V | 9 | CONSERVATION | null | false | false | null | null | 5,441,539 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.527486 | 0.077745 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875760,"numValue":-0.52748559648777,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875761,"numValue":0.0777451749530923,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463318 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,318 | train | mutant | 5,055,032 | 5,060,731 | 5,061,698 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181W | L181W | 1 | 1 | 0 | 0 | 181 | L | W | 9 | CONSERVATION | null | false | false | null | null | 5,441,540 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.183478 | 0.261564 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875762,"numValue":-1.18347802421881,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875763,"numValue":0.261564302434251,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463319 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,319 | train | mutant | 5,055,033 | 5,060,731 | 5,061,699 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L181Y | L181Y | 1 | 1 | 0 | 0 | 181 | L | Y | 9 | CONSERVATION | null | false | false | null | null | 5,441,541 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.776774 | 0.235713 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875764,"numValue":-0.776774139999186,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875765,"numValue":0.235713112523374,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462414,"numValue":9.0,"position":181,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463321 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,321 | train | mutant | 5,054,765 | 5,060,731 | 5,061,431 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182A | R182A | 1 | 1 | 0 | 0 | 182 | R | A | 5 | CONSERVATION | null | false | false | null | null | 5,441,273 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.540092 | 0.093651 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875228,"numValue":-0.540091700432484,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875229,"numValue":0.0936514729132565,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463322 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,322 | train | mutant | 5,054,766 | 5,060,731 | 5,061,432 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182C | R182C | 1 | 1 | 0 | 0 | 182 | R | C | 5 | CONSERVATION | null | false | false | null | null | 5,441,274 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.366777 | 0.131493 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875230,"numValue":-0.366777276489174,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875231,"numValue":0.131493152794948,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463323 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,323 | train | mutant | 5,054,767 | 5,060,731 | 5,061,433 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182D | R182D | 1 | 1 | 0 | 0 | 182 | R | D | 5 | CONSERVATION | null | false | false | null | null | 5,441,275 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.858795 | 0.402585 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875232,"numValue":-0.85879545695786,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875233,"numValue":0.402585297763036,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463324 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,324 | train | mutant | 5,054,768 | 5,060,731 | 5,061,434 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182E | R182E | 1 | 1 | 0 | 0 | 182 | R | E | 5 | CONSERVATION | null | false | false | null | null | 5,441,276 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.289669 | 0.126776 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875234,"numValue":-0.289668529672552,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875235,"numValue":0.126775616463939,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463325 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,325 | train | mutant | 5,054,769 | 5,060,731 | 5,061,435 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182F | R182F | 1 | 1 | 0 | 0 | 182 | R | F | 5 | CONSERVATION | null | false | false | null | null | 5,441,277 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.635689 | 0.268875 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875236,"numValue":-0.635689106004583,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875237,"numValue":0.268874542794732,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463326 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,326 | train | mutant | 5,054,770 | 5,060,731 | 5,061,436 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182G | R182G | 1 | 1 | 0 | 0 | 182 | R | G | 5 | CONSERVATION | null | false | false | null | null | 5,441,278 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.735579 | 0.081986 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875238,"numValue":-0.735579209141631,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875239,"numValue":0.0819855178759977,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463327 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,327 | train | mutant | 5,054,771 | 5,060,731 | 5,061,437 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182H | R182H | 1 | 1 | 0 | 0 | 182 | R | H | 5 | CONSERVATION | null | false | false | null | null | 5,441,279 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.517086 | 0.210222 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875240,"numValue":-0.517086113011006,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875241,"numValue":0.210222211935741,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463328 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,328 | train | mutant | 5,054,772 | 5,060,731 | 5,061,438 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182I | R182I | 1 | 1 | 0 | 0 | 182 | R | I | 5 | CONSERVATION | null | false | false | null | null | 5,441,280 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.195016 | 0.128129 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875242,"numValue":-0.195015933847994,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875243,"numValue":0.1281294947378,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463329 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,329 | train | mutant | 5,054,773 | 5,060,731 | 5,061,439 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182K | R182K | 1 | 1 | 0 | 0 | 182 | R | K | 5 | CONSERVATION | null | false | false | null | null | 5,441,281 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.03064 | 0.087966 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875244,"numValue":0.0306395965500206,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875245,"numValue":0.0879656949400356,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463330 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,330 | train | mutant | 5,054,774 | 5,060,731 | 5,061,440 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182L | R182L | 1 | 1 | 0 | 0 | 182 | R | L | 5 | CONSERVATION | null | false | false | null | null | 5,441,282 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.501792 | 0.071329 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875246,"numValue":-0.501791981280023,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875247,"numValue":0.0713291774175913,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463331 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,331 | train | mutant | 5,054,775 | 5,060,731 | 5,061,441 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182M | R182M | 1 | 1 | 0 | 0 | 182 | R | M | 5 | CONSERVATION | null | false | false | null | null | 5,441,283 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.505413 | 0.130837 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875248,"numValue":-0.505413134790059,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875249,"numValue":0.130836995897024,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463332 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,332 | train | mutant | 5,054,776 | 5,060,731 | 5,061,442 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182N | R182N | 1 | 1 | 0 | 0 | 182 | R | N | 5 | CONSERVATION | null | false | false | null | null | 5,441,284 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.581387 | 0.157629 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875250,"numValue":-0.581386998969667,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875251,"numValue":0.157628845492353,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463333 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,333 | train | mutant | 5,054,777 | 5,060,731 | 5,061,443 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182P | R182P | 1 | 1 | 0 | 0 | 182 | R | P | 5 | CONSERVATION | null | false | false | null | null | 5,441,285 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.752603 | 0.123013 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875252,"numValue":-0.752603214862334,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875253,"numValue":0.123012913879008,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463334 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,334 | train | mutant | 5,054,778 | 5,060,731 | 5,061,444 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182Q | R182Q | 1 | 1 | 0 | 0 | 182 | R | Q | 5 | CONSERVATION | null | false | false | null | null | 5,441,286 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.71557 | 0.164038 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875254,"numValue":-0.715569839576119,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875255,"numValue":0.164037628302792,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463336 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,336 | train | mutant | 5,055,020 | 5,060,731 | 5,061,686 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182T | R182T | 1 | 1 | 0 | 0 | 182 | R | T | 5 | CONSERVATION | null | false | false | null | null | 5,441,528 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.538461 | 0.118981 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875738,"numValue":-0.53846085333278,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875739,"numValue":0.118980904123167,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463337 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,337 | train | mutant | 5,055,021 | 5,060,731 | 5,061,687 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182V | R182V | 1 | 1 | 0 | 0 | 182 | R | V | 5 | CONSERVATION | null | false | false | null | null | 5,441,529 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.377865 | 0.073368 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875740,"numValue":-0.377864904273208,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875741,"numValue":0.0733678161011275,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463338 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,338 | train | mutant | 5,055,022 | 5,060,731 | 5,061,688 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182W | R182W | 1 | 1 | 0 | 0 | 182 | R | W | 5 | CONSERVATION | null | false | false | null | null | 5,441,530 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.678818 | 0.115785 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875742,"numValue":-0.678817902414459,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875743,"numValue":0.115785419391808,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463339 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,339 | train | mutant | 5,055,023 | 5,060,731 | 5,061,689 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R182Y | R182Y | 1 | 1 | 0 | 0 | 182 | R | Y | 5 | CONSERVATION | null | false | false | null | null | 5,441,531 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.619832 | 0.090074 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875744,"numValue":-0.61983209802449,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875745,"numValue":0.0900741185305904,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462415,"numValue":5.0,"position":182,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463340 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,340 | train | mutant | 5,054,779 | 5,060,731 | 5,061,445 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delE183 | delE183 | 1 | 0 | 1 | 0 | 183 | E | - | 4 | CONSERVATION | null | false | false | null | null | 5,441,287 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.911636 | 0.199046 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875256,"numValue":-0.911635662769066,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875257,"numValue":0.199046411272848,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463341 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,341 | train | mutant | 5,054,780 | 5,060,731 | 5,061,446 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183A | E183A | 1 | 1 | 0 | 0 | 183 | E | A | 4 | CONSERVATION | null | false | false | null | null | 5,441,288 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.209242 | 0.086051 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875258,"numValue":-0.209241711645636,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875259,"numValue":0.0860505365951765,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463342 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,342 | train | mutant | 5,054,781 | 5,060,731 | 5,061,447 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183C | E183C | 1 | 1 | 0 | 0 | 183 | E | C | 4 | CONSERVATION | null | false | false | null | null | 5,441,289 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.201795 | 0.083698 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875260,"numValue":-0.201794583050344,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875261,"numValue":0.0836975785179965,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463343 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,343 | train | mutant | 5,054,782 | 5,060,731 | 5,061,448 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183D | E183D | 1 | 1 | 0 | 0 | 183 | E | D | 4 | CONSERVATION | null | false | false | null | null | 5,441,290 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.151511 | 0.119931 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875262,"numValue":-0.151510503251016,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875263,"numValue":0.119931140876286,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463344 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,344 | train | mutant | 5,055,003 | 5,060,731 | 5,061,669 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183F | E183F | 1 | 1 | 0 | 0 | 183 | E | F | 4 | CONSERVATION | null | false | false | null | null | 5,441,511 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.401008 | 0.12094 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875704,"numValue":-0.401007763012244,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875705,"numValue":0.120939542359774,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463347 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,347 | train | mutant | 5,055,006 | 5,060,731 | 5,061,672 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183I | E183I | 1 | 1 | 0 | 0 | 183 | E | I | 4 | CONSERVATION | null | false | false | null | null | 5,441,514 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.467714 | 0.18519 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875710,"numValue":-0.467714025537254,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875711,"numValue":0.1851896698545,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463348 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,348 | train | mutant | 5,055,007 | 5,060,731 | 5,061,673 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183K | E183K | 1 | 1 | 0 | 0 | 183 | E | K | 4 | CONSERVATION | null | false | false | null | null | 5,441,515 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.115679 | 0.169147 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875712,"numValue":-0.115679497012354,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875713,"numValue":0.169147441366392,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463349 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,349 | train | mutant | 5,055,008 | 5,060,731 | 5,061,674 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183L | E183L | 1 | 1 | 0 | 0 | 183 | E | L | 4 | CONSERVATION | null | false | false | null | null | 5,441,516 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.467228 | 0.073761 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875714,"numValue":-0.46722763814323,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875715,"numValue":0.0737611782348345,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463350 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,350 | train | mutant | 5,055,009 | 5,060,731 | 5,061,675 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183M | E183M | 1 | 1 | 0 | 0 | 183 | E | M | 4 | CONSERVATION | null | false | false | null | null | 5,441,517 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.46041 | 0.114429 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875716,"numValue":-0.460410169889217,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875717,"numValue":0.114428923385845,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463351 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,351 | train | mutant | 5,055,010 | 5,060,731 | 5,061,676 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183N | E183N | 1 | 1 | 0 | 0 | 183 | E | N | 4 | CONSERVATION | null | false | false | null | null | 5,441,518 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.321502 | 0.157634 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875718,"numValue":-0.321502258991072,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875719,"numValue":0.157633506332438,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463352 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,352 | train | mutant | 5,055,011 | 5,060,731 | 5,061,677 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183P | E183P | 1 | 1 | 0 | 0 | 183 | E | P | 4 | CONSERVATION | null | false | false | null | null | 5,441,519 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.541944 | 0.117562 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875720,"numValue":-0.541944160901138,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875721,"numValue":0.117561901782372,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463354 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,354 | train | mutant | 5,055,013 | 5,060,731 | 5,061,679 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183R | E183R | 1 | 1 | 0 | 0 | 183 | E | R | 4 | CONSERVATION | null | false | false | null | null | 5,441,521 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.342517 | 0.06123 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875724,"numValue":-0.342516518448228,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875725,"numValue":0.0612298711964073,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463355 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,355 | train | mutant | 5,055,014 | 5,060,731 | 5,061,680 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183S | E183S | 1 | 1 | 0 | 0 | 183 | E | S | 4 | CONSERVATION | null | false | false | null | null | 5,441,522 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.265124 | 0.066571 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875726,"numValue":-0.265123907316322,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875727,"numValue":0.066571162009684,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463356 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,356 | train | mutant | 5,055,015 | 5,060,731 | 5,061,681 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183T | E183T | 1 | 1 | 0 | 0 | 183 | E | T | 4 | CONSERVATION | null | false | false | null | null | 5,441,523 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.180754 | 0.10361 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875728,"numValue":-0.180753763189419,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875729,"numValue":0.10361015584285,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463357 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,357 | train | mutant | 5,055,016 | 5,060,731 | 5,061,682 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183V | E183V | 1 | 1 | 0 | 0 | 183 | E | V | 4 | CONSERVATION | null | false | false | null | null | 5,441,524 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.211031 | 0.05916 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875730,"numValue":-0.211030708072591,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875731,"numValue":0.0591603049657899,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463359 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,359 | train | mutant | 5,055,018 | 5,060,731 | 5,061,684 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E183Y | E183Y | 1 | 1 | 0 | 0 | 183 | E | Y | 4 | CONSERVATION | null | false | false | null | null | 5,441,526 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.5878 | 0.226937 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875734,"numValue":-0.58780044262019,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875735,"numValue":0.226937452962626,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462416,"numValue":4.0,"position":183,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463361 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,361 | train | mutant | 5,054,784 | 5,060,731 | 5,061,450 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184A | S184A | 1 | 1 | 0 | 0 | 184 | S | A | 5 | CONSERVATION | null | false | false | null | null | 5,441,292 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.4693 | 0.108668 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875266,"numValue":-0.469300115802722,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875267,"numValue":0.108667933500028,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463362 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,362 | train | mutant | 5,054,785 | 5,060,731 | 5,061,451 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184C | S184C | 1 | 1 | 0 | 0 | 184 | S | C | 5 | CONSERVATION | null | false | false | null | null | 5,441,293 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.453121 | 0.116963 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875268,"numValue":-0.453120999079803,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875269,"numValue":0.116963334990698,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463363 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,363 | train | mutant | 5,054,786 | 5,060,731 | 5,061,452 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184D | S184D | 1 | 1 | 0 | 0 | 184 | S | D | 5 | CONSERVATION | null | false | false | null | null | 5,441,294 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.500509 | 0.153535 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875270,"numValue":-0.500509292549918,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875271,"numValue":0.153535095567174,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463364 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,364 | train | mutant | 5,054,787 | 5,060,731 | 5,061,453 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184E | S184E | 1 | 1 | 0 | 0 | 184 | S | E | 5 | CONSERVATION | null | false | false | null | null | 5,441,295 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.957847 | 0.224257 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875272,"numValue":-0.957847074963707,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875273,"numValue":0.224256831442793,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463365 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,365 | train | mutant | 5,054,788 | 5,060,731 | 5,061,454 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184F | S184F | 1 | 1 | 0 | 0 | 184 | S | F | 5 | CONSERVATION | null | false | false | null | null | 5,441,296 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.800298 | 0.140801 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875274,"numValue":-0.800298293765408,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875275,"numValue":0.140800722749449,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463366 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,366 | train | mutant | 5,054,789 | 5,060,731 | 5,061,455 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184G | S184G | 1 | 1 | 0 | 0 | 184 | S | G | 5 | CONSERVATION | null | false | false | null | null | 5,441,297 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.478678 | 0.063312 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875276,"numValue":-0.478678109135486,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875277,"numValue":0.0633124558556991,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463367 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,367 | train | mutant | 5,054,790 | 5,060,731 | 5,061,456 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184H | S184H | 1 | 1 | 0 | 0 | 184 | S | H | 5 | CONSERVATION | null | false | false | null | null | 5,441,298 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.108814 | 0.124184 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875278,"numValue":-0.108814015720758,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875279,"numValue":0.12418425322408,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463368 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,368 | train | mutant | 5,054,791 | 5,060,731 | 5,061,457 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184I | S184I | 1 | 1 | 0 | 0 | 184 | S | I | 5 | CONSERVATION | null | false | false | null | null | 5,441,299 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.812602 | 0.273012 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875280,"numValue":-0.812602081575875,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875281,"numValue":0.273012474930028,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463369 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,369 | train | mutant | 5,054,792 | 5,060,731 | 5,061,458 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184K | S184K | 1 | 1 | 0 | 0 | 184 | S | K | 5 | CONSERVATION | null | false | false | null | null | 5,441,300 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.538418 | 0.195278 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875282,"numValue":-0.538418458842148,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875283,"numValue":0.195278409376589,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463370 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,370 | train | mutant | 5,054,793 | 5,060,731 | 5,061,459 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184L | S184L | 1 | 1 | 0 | 0 | 184 | S | L | 5 | CONSERVATION | null | false | false | null | null | 5,441,301 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.816144 | 0.100786 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875284,"numValue":-0.816144064651598,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875285,"numValue":0.100785878293015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463371 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,371 | train | mutant | 5,054,794 | 5,060,731 | 5,061,460 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184M | S184M | 1 | 1 | 0 | 0 | 184 | S | M | 5 | CONSERVATION | null | false | false | null | null | 5,441,302 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.526261 | 0.124663 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875286,"numValue":-0.526260689405288,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875287,"numValue":0.124662595880424,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463372 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,372 | train | mutant | 5,054,795 | 5,060,731 | 5,061,461 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184N | S184N | 1 | 1 | 0 | 0 | 184 | S | N | 5 | CONSERVATION | null | false | false | null | null | 5,441,303 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.161467 | 0.163865 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875288,"numValue":0.161466823837005,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875289,"numValue":0.163864857984043,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463373 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,373 | train | mutant | 5,054,796 | 5,060,731 | 5,061,462 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184P | S184P | 1 | 1 | 0 | 0 | 184 | S | P | 5 | CONSERVATION | null | false | false | null | null | 5,441,304 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.773812 | 0.145227 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875290,"numValue":-0.773812208049047,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875291,"numValue":0.145226605415992,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463374 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,374 | train | mutant | 5,054,797 | 5,060,731 | 5,061,463 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184Q | S184Q | 1 | 1 | 0 | 0 | 184 | S | Q | 5 | CONSERVATION | null | false | false | null | null | 5,441,305 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.250912 | 0.101432 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875292,"numValue":-0.250911537414814,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875293,"numValue":0.101431500415405,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463375 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,375 | train | mutant | 5,054,798 | 5,060,731 | 5,061,464 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184R | S184R | 1 | 1 | 0 | 0 | 184 | S | R | 5 | CONSERVATION | null | false | false | null | null | 5,441,306 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.528643 | 0.058293 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875294,"numValue":-0.528643464089584,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875295,"numValue":0.0582934972501842,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463376 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,376 | train | mutant | 5,054,999 | 5,060,731 | 5,061,665 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184T | S184T | 1 | 1 | 0 | 0 | 184 | S | T | 5 | CONSERVATION | null | false | false | null | null | 5,441,507 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.097792 | 0.079884 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875696,"numValue":-0.0977920866277784,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875697,"numValue":0.0798837982335097,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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