row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:5463377 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,377 | train | mutant | 5,055,000 | 5,060,731 | 5,061,666 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184V | S184V | 1 | 1 | 0 | 0 | 184 | S | V | 5 | CONSERVATION | null | false | false | null | null | 5,441,508 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.42872 | 0.067712 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875698,"numValue":-0.428719713517953,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875699,"numValue":0.0677121739706447,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463378 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,378 | train | mutant | 5,055,001 | 5,060,731 | 5,061,667 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S184W | S184W | 1 | 1 | 0 | 0 | 184 | S | W | 5 | CONSERVATION | null | false | false | null | null | 5,441,509 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.87445 | 0.1236 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875700,"numValue":-0.874449807780251,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875701,"numValue":0.123599732799784,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462417,"numValue":5.0,"position":184,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463380 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,380 | train | mutant | 5,054,799 | 5,060,731 | 5,061,465 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delQ185 | delQ185 | 1 | 0 | 1 | 0 | 185 | Q | - | 7 | CONSERVATION | null | false | false | null | null | 5,441,307 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.595823 | 0.14725 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875296,"numValue":-0.595822833806733,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875297,"numValue":0.147250367719532,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463381 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,381 | train | mutant | 5,054,800 | 5,060,731 | 5,061,466 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185A | Q185A | 1 | 1 | 0 | 0 | 185 | Q | A | 7 | CONSERVATION | null | false | false | null | null | 5,441,308 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.191465 | 0.060678 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875298,"numValue":-0.191465395257595,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875299,"numValue":0.0606782767341877,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463382 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,382 | train | mutant | 5,054,801 | 5,060,731 | 5,061,467 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185C | Q185C | 1 | 1 | 0 | 0 | 185 | Q | C | 7 | CONSERVATION | null | false | false | null | null | 5,441,309 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.27171 | 0.072121 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875300,"numValue":-0.271709865897096,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875301,"numValue":0.0721210733020855,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463384 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,384 | train | mutant | 5,054,803 | 5,060,731 | 5,061,469 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185E | Q185E | 1 | 1 | 0 | 0 | 185 | Q | E | 7 | CONSERVATION | null | false | false | null | null | 5,441,311 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.115637 | 0.072448 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875304,"numValue":0.11563735791022,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875305,"numValue":0.0724477151907473,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463385 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,385 | train | mutant | 5,054,804 | 5,060,731 | 5,061,470 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185F | Q185F | 1 | 1 | 0 | 0 | 185 | Q | F | 7 | CONSERVATION | null | false | false | null | null | 5,441,312 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.028742 | 0.59705 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875306,"numValue":-1.02874221962932,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875307,"numValue":0.597050103232819,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463386 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,386 | train | mutant | 5,054,805 | 5,060,731 | 5,061,471 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185G | Q185G | 1 | 1 | 0 | 0 | 185 | Q | G | 7 | CONSERVATION | null | false | false | null | null | 5,441,313 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.627036 | 0.065814 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875308,"numValue":-0.627035969075645,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875309,"numValue":0.0658140628080125,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463387 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,387 | train | mutant | 5,054,806 | 5,060,731 | 5,061,472 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185H | Q185H | 1 | 1 | 0 | 0 | 185 | Q | H | 7 | CONSERVATION | null | false | false | null | null | 5,441,314 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.009095 | 0.096262 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875310,"numValue":0.00909502287722275,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875311,"numValue":0.0962621818318219,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463388 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,388 | train | mutant | 5,054,807 | 5,060,731 | 5,061,473 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185I | Q185I | 1 | 1 | 0 | 0 | 185 | Q | I | 7 | CONSERVATION | null | false | false | null | null | 5,441,315 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.976958 | 0.426768 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875312,"numValue":-0.97695805164115,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875313,"numValue":0.426767843076537,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463389 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,389 | train | mutant | 5,054,808 | 5,060,731 | 5,061,474 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185K | Q185K | 1 | 1 | 0 | 0 | 185 | Q | K | 7 | CONSERVATION | null | false | false | null | null | 5,441,316 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.625758 | 0.150221 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875314,"numValue":-0.625758388115496,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875315,"numValue":0.150220535948724,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463390 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,390 | train | mutant | 5,054,809 | 5,060,731 | 5,061,475 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185L | Q185L | 1 | 1 | 0 | 0 | 185 | Q | L | 7 | CONSERVATION | null | false | false | null | null | 5,441,317 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.632713 | 0.077265 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875316,"numValue":-0.632712999992817,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875317,"numValue":0.0772650445772642,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463391 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,391 | train | mutant | 5,054,810 | 5,060,731 | 5,061,476 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185M | Q185M | 1 | 1 | 0 | 0 | 185 | Q | M | 7 | CONSERVATION | null | false | false | null | null | 5,441,318 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.544837 | 0.115624 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875318,"numValue":-0.544837137956876,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875319,"numValue":0.115623758472713,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463392 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,392 | train | mutant | 5,054,811 | 5,060,731 | 5,061,477 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185N | Q185N | 1 | 1 | 0 | 0 | 185 | Q | N | 7 | CONSERVATION | null | false | false | null | null | 5,441,319 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.141302 | 0.107239 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875320,"numValue":0.141301986523468,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875321,"numValue":0.107239098702068,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463393 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,393 | train | mutant | 5,054,812 | 5,060,731 | 5,061,478 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185P | Q185P | 1 | 1 | 0 | 0 | 185 | Q | P | 7 | CONSERVATION | null | false | false | null | null | 5,441,320 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.987259 | 0.202203 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875322,"numValue":-0.987259402087641,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875323,"numValue":0.202203268493918,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463394 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,394 | train | mutant | 5,054,993 | 5,060,731 | 5,061,659 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185R | Q185R | 1 | 1 | 0 | 0 | 185 | Q | R | 7 | CONSERVATION | null | false | false | null | null | 5,441,501 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.691206 | 0.070964 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875684,"numValue":-0.691206223817691,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875685,"numValue":0.0709640357128891,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463395 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,395 | train | mutant | 5,054,994 | 5,060,731 | 5,061,660 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185S | Q185S | 1 | 1 | 0 | 0 | 185 | Q | S | 7 | CONSERVATION | null | false | false | null | null | 5,441,502 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.216297 | 0.0586 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875686,"numValue":-0.216296818896833,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875687,"numValue":0.0585996505966115,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463396 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,396 | train | mutant | 5,054,995 | 5,060,731 | 5,061,661 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185T | Q185T | 1 | 1 | 0 | 0 | 185 | Q | T | 7 | CONSERVATION | null | false | false | null | null | 5,441,503 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.658736 | 0.105697 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875688,"numValue":-0.658736449445448,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875689,"numValue":0.105696999105342,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463397 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,397 | train | mutant | 5,054,996 | 5,060,731 | 5,061,662 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185V | Q185V | 1 | 1 | 0 | 0 | 185 | Q | V | 7 | CONSERVATION | null | false | false | null | null | 5,441,504 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.573501 | 0.070609 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875690,"numValue":-0.573500666005317,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875691,"numValue":0.0706089818538491,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463398 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,398 | train | mutant | 5,054,997 | 5,060,731 | 5,061,663 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185W | Q185W | 1 | 1 | 0 | 0 | 185 | Q | W | 7 | CONSERVATION | null | false | false | null | null | 5,441,505 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.615134 | 0.082046 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875692,"numValue":-0.615133524289441,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875693,"numValue":0.0820460449499718,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463399 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,399 | train | mutant | 5,054,998 | 5,060,731 | 5,061,664 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q185Y | Q185Y | 1 | 1 | 0 | 0 | 185 | Q | Y | 7 | CONSERVATION | null | false | false | null | null | 5,441,506 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.332186 | 0.179957 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875694,"numValue":-0.332186372948612,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875695,"numValue":0.179957334159089,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462418,"numValue":7.0,"position":185,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463400 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,400 | train | mutant | 5,054,813 | 5,060,731 | 5,061,479 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delS186 | delS186 | 1 | 0 | 1 | 0 | 186 | S | - | 4 | CONSERVATION | null | false | false | null | null | 5,441,321 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.874534 | 0.360418 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875324,"numValue":-0.874534207294055,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875325,"numValue":0.360418166741554,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463401 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,401 | train | mutant | 5,054,814 | 5,060,731 | 5,061,480 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186A | S186A | 1 | 1 | 0 | 0 | 186 | S | A | 4 | CONSERVATION | null | false | false | null | null | 5,441,322 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.063142 | 0.076233 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875326,"numValue":-0.0631416137201085,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875327,"numValue":0.0762331473519804,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463402 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,402 | train | mutant | 5,054,815 | 5,060,731 | 5,061,481 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186C | S186C | 1 | 1 | 0 | 0 | 186 | S | C | 4 | CONSERVATION | null | false | false | null | null | 5,441,323 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.256573 | 0.090453 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875328,"numValue":-0.256572989633621,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875329,"numValue":0.0904530512141728,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463403 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,403 | train | mutant | 5,054,816 | 5,060,731 | 5,061,482 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186D | S186D | 1 | 1 | 0 | 0 | 186 | S | D | 4 | CONSERVATION | null | false | false | null | null | 5,441,324 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.33833 | 0.125828 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875330,"numValue":-0.338330062498354,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875331,"numValue":0.125827614360176,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463404 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,404 | train | mutant | 5,054,817 | 5,060,731 | 5,061,483 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186E | S186E | 1 | 1 | 0 | 0 | 186 | S | E | 4 | CONSERVATION | null | false | false | null | null | 5,441,325 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.217908 | 0.085905 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875332,"numValue":-0.217908320317831,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875333,"numValue":0.0859053482341881,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463405 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,405 | train | mutant | 5,054,818 | 5,060,731 | 5,061,484 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186F | S186F | 1 | 1 | 0 | 0 | 186 | S | F | 4 | CONSERVATION | null | false | false | null | null | 5,441,326 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.551449 | 0.115888 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875334,"numValue":-0.551449146164424,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875335,"numValue":0.115887638638045,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463406 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,406 | train | mutant | 5,054,819 | 5,060,731 | 5,061,485 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186G | S186G | 1 | 1 | 0 | 0 | 186 | S | G | 4 | CONSERVATION | null | false | false | null | null | 5,441,327 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.066544 | 0.043307 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875336,"numValue":0.0665440269817948,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875337,"numValue":0.043306623420881,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463407 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,407 | train | mutant | 5,054,820 | 5,060,731 | 5,061,486 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186H | S186H | 1 | 1 | 0 | 0 | 186 | S | H | 4 | CONSERVATION | null | false | false | null | null | 5,441,328 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.143622 | 0.157666 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875338,"numValue":-0.143622191025808,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875339,"numValue":0.157665685283158,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463408 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,408 | train | mutant | 5,054,821 | 5,060,731 | 5,061,487 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186I | S186I | 1 | 1 | 0 | 0 | 186 | S | I | 4 | CONSERVATION | null | false | false | null | null | 5,441,329 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.627905 | 0.180667 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875340,"numValue":-0.62790486459222,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875341,"numValue":0.18066731418292,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463409 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,409 | train | mutant | 5,054,822 | 5,060,731 | 5,061,488 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186K | S186K | 1 | 1 | 0 | 0 | 186 | S | K | 4 | CONSERVATION | null | false | false | null | null | 5,441,330 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.288791 | 0.109057 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875342,"numValue":-0.288790823252804,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875343,"numValue":0.109057400959143,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463410 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,410 | train | mutant | 5,054,823 | 5,060,731 | 5,061,489 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186L | S186L | 1 | 1 | 0 | 0 | 186 | S | L | 4 | CONSERVATION | null | false | false | null | null | 5,441,331 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.112287 | 0.046181 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875344,"numValue":-0.112287299290579,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875345,"numValue":0.0461806634195083,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463411 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,411 | train | mutant | 5,054,824 | 5,060,731 | 5,061,490 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186M | S186M | 1 | 1 | 0 | 0 | 186 | S | M | 4 | CONSERVATION | null | false | false | null | null | 5,441,332 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.266195 | 0.095133 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875346,"numValue":-0.266195453605886,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875347,"numValue":0.0951329815888836,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463412 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,412 | train | mutant | 5,054,825 | 5,060,731 | 5,061,491 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186N | S186N | 1 | 1 | 0 | 0 | 186 | S | N | 4 | CONSERVATION | null | false | false | null | null | 5,441,333 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.022101 | 0.150825 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875348,"numValue":-0.0221013205979603,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875349,"numValue":0.150825104370096,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463413 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,413 | train | mutant | 5,054,826 | 5,060,731 | 5,061,492 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186P | S186P | 1 | 1 | 0 | 0 | 186 | S | P | 4 | CONSERVATION | null | false | false | null | null | 5,441,334 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.319774 | 0.115261 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875350,"numValue":0.319773853485215,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875351,"numValue":0.11526104295874,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463414 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,414 | train | mutant | 5,054,827 | 5,060,731 | 5,061,493 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186Q | S186Q | 1 | 1 | 0 | 0 | 186 | S | Q | 4 | CONSERVATION | null | false | false | null | null | 5,441,335 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.016054 | 0.109155 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875352,"numValue":-0.0160537209705082,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875353,"numValue":0.109154895518171,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463415 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,415 | train | mutant | 5,054,828 | 5,060,731 | 5,061,494 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186R | S186R | 1 | 1 | 0 | 0 | 186 | S | R | 4 | CONSERVATION | null | false | false | null | null | 5,441,336 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.024661 | 0.04535 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875354,"numValue":-0.0246609518169694,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875355,"numValue":0.0453495717853172,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463416 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,416 | train | mutant | 5,054,989 | 5,060,731 | 5,061,655 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186T | S186T | 1 | 1 | 0 | 0 | 186 | S | T | 4 | CONSERVATION | null | false | false | null | null | 5,441,497 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.048336 | 0.081251 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875676,"numValue":-0.0483361040325046,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875677,"numValue":0.0812510844035042,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463417 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,417 | train | mutant | 5,054,990 | 5,060,731 | 5,061,656 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186V | S186V | 1 | 1 | 0 | 0 | 186 | S | V | 4 | CONSERVATION | null | false | false | null | null | 5,441,498 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.516974 | 0.07666 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875678,"numValue":-0.516974189001854,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875679,"numValue":0.0766603484616434,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463418 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,418 | train | mutant | 5,054,991 | 5,060,731 | 5,061,657 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186W | S186W | 1 | 1 | 0 | 0 | 186 | S | W | 4 | CONSERVATION | null | false | false | null | null | 5,441,499 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.302313 | 0.076924 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875680,"numValue":-0.302313324974681,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875681,"numValue":0.0769243563212245,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463419 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,419 | train | mutant | 5,054,992 | 5,060,731 | 5,061,658 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | S186Y | S186Y | 1 | 1 | 0 | 0 | 186 | S | Y | 4 | CONSERVATION | null | false | false | null | null | 5,441,500 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.166782 | 0.086449 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875682,"numValue":-0.16678209694707,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875683,"numValue":0.0864490703459636,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462419,"numValue":4.0,"position":186,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463420 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,420 | train | mutant | 5,054,829 | 5,060,731 | 5,061,495 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delY187 | delY187 | 1 | 0 | 1 | 0 | 187 | Y | - | 4 | CONSERVATION | null | false | false | null | null | 5,441,337 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.976716 | 0.237429 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875356,"numValue":-0.976715943345254,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875357,"numValue":0.237428876298591,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463421 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,421 | train | mutant | 5,054,830 | 5,060,731 | 5,061,496 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187A | Y187A | 1 | 1 | 0 | 0 | 187 | Y | A | 4 | CONSERVATION | null | false | false | null | null | 5,441,338 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.201952 | 0.057073 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875358,"numValue":0.201952285447724,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875359,"numValue":0.0570734042408856,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463422 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,422 | train | mutant | 5,054,831 | 5,060,731 | 5,061,497 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187C | Y187C | 1 | 1 | 0 | 0 | 187 | Y | C | 4 | CONSERVATION | null | false | false | null | null | 5,441,339 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.17674 | 0.08367 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875360,"numValue":0.176739694475548,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875361,"numValue":0.0836704434901073,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463423 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,423 | train | mutant | 5,054,832 | 5,060,731 | 5,061,498 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187D | Y187D | 1 | 1 | 0 | 0 | 187 | Y | D | 4 | CONSERVATION | null | false | false | null | null | 5,441,340 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.210176 | 0.089952 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875362,"numValue":0.210175795076269,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875363,"numValue":0.0899523620642733,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463424 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,424 | train | mutant | 5,054,833 | 5,060,731 | 5,061,499 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187E | Y187E | 1 | 1 | 0 | 0 | 187 | Y | E | 4 | CONSERVATION | null | false | false | null | null | 5,441,341 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.249458 | 0.106391 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875364,"numValue":0.249457738391196,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875365,"numValue":0.106391400430808,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463425 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,425 | train | mutant | 5,054,834 | 5,060,731 | 5,061,500 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187F | Y187F | 1 | 1 | 0 | 0 | 187 | Y | F | 4 | CONSERVATION | null | false | false | null | null | 5,441,342 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.340838 | 0.133873 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875366,"numValue":-0.340838041393687,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875367,"numValue":0.133872990511519,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463426 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,426 | train | mutant | 5,054,835 | 5,060,731 | 5,061,501 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187G | Y187G | 1 | 1 | 0 | 0 | 187 | Y | G | 4 | CONSERVATION | null | false | false | null | null | 5,441,343 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.150875 | 0.047944 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875368,"numValue":0.150874585891541,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875369,"numValue":0.0479440379954238,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463427 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,427 | train | mutant | 5,054,836 | 5,060,731 | 5,061,502 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187H | Y187H | 1 | 1 | 0 | 0 | 187 | Y | H | 4 | CONSERVATION | null | false | false | null | null | 5,441,344 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.026889 | 0.090483 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875370,"numValue":0.026889216460108,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875371,"numValue":0.0904833147511598,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463428 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,428 | train | mutant | 5,054,837 | 5,060,731 | 5,061,503 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187I | Y187I | 1 | 1 | 0 | 0 | 187 | Y | I | 4 | CONSERVATION | null | false | false | null | null | 5,441,345 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.099783 | 0.125355 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875372,"numValue":-0.0997834784392251,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875373,"numValue":0.125354571015161,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463429 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,429 | train | mutant | 5,054,838 | 5,060,731 | 5,061,504 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187K | Y187K | 1 | 1 | 0 | 0 | 187 | Y | K | 4 | CONSERVATION | null | false | false | null | null | 5,441,346 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.221168 | 0.097541 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875374,"numValue":0.221168354492004,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875375,"numValue":0.0975409758873354,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463430 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,430 | train | mutant | 5,054,839 | 5,060,731 | 5,061,505 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187L | Y187L | 1 | 1 | 0 | 0 | 187 | Y | L | 4 | CONSERVATION | null | false | false | null | null | 5,441,347 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.026665 | 0.042643 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875376,"numValue":0.0266651130533051,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875377,"numValue":0.0426425047865391,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463431 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,431 | train | mutant | 5,054,840 | 5,060,731 | 5,061,506 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187M | Y187M | 1 | 1 | 0 | 0 | 187 | Y | M | 4 | CONSERVATION | null | false | false | null | null | 5,441,348 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.103324 | 0.072169 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875378,"numValue":-0.103324439960958,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875379,"numValue":0.0721693417281661,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463432 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,432 | train | mutant | 5,054,841 | 5,060,731 | 5,061,507 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187N | Y187N | 1 | 1 | 0 | 0 | 187 | Y | N | 4 | CONSERVATION | null | false | false | null | null | 5,441,349 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.138581 | 0.109145 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875380,"numValue":0.138580822079613,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875381,"numValue":0.109145382296629,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463433 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,433 | train | mutant | 5,054,842 | 5,060,731 | 5,061,508 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187P | Y187P | 1 | 1 | 0 | 0 | 187 | Y | P | 4 | CONSERVATION | null | false | false | null | null | 5,441,350 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.081298 | 0.065313 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875382,"numValue":-0.0812984589698426,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875383,"numValue":0.0653126074926197,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463434 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,434 | train | mutant | 5,054,843 | 5,060,731 | 5,061,509 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187Q | Y187Q | 1 | 1 | 0 | 0 | 187 | Y | Q | 4 | CONSERVATION | null | false | false | null | null | 5,441,351 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.264969 | 0.061967 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875384,"numValue":0.264969397275164,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875385,"numValue":0.0619674140238613,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463435 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,435 | train | mutant | 5,054,844 | 5,060,731 | 5,061,510 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187R | Y187R | 1 | 1 | 0 | 0 | 187 | Y | R | 4 | CONSERVATION | null | false | false | null | null | 5,441,352 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.030688 | 0.04494 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875386,"numValue":-0.0306881203645989,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875387,"numValue":0.0449400244055633,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463436 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,436 | train | mutant | 5,054,845 | 5,060,731 | 5,061,511 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187S | Y187S | 1 | 1 | 0 | 0 | 187 | Y | S | 4 | CONSERVATION | null | false | false | null | null | 5,441,353 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.219052 | 0.052823 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875388,"numValue":0.21905246078789,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875389,"numValue":0.0528234587104637,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463437 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,437 | train | mutant | 5,054,846 | 5,060,731 | 5,061,512 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y187T | Y187T | 1 | 1 | 0 | 0 | 187 | Y | T | 4 | CONSERVATION | null | false | false | null | null | 5,441,354 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.138406 | 0.069882 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875390,"numValue":0.138405880958633,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875391,"numValue":0.0698820184949158,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462420,"numValue":4.0,"position":187,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463440 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,440 | train | mutant | 5,054,849 | 5,060,731 | 5,061,515 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delL188 | delL188 | 1 | 0 | 1 | 0 | 188 | L | - | 9 | CONSERVATION | null | false | false | null | null | 5,441,357 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.064494 | 0.376485 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875396,"numValue":-1.06449373619805,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875397,"numValue":0.3764847848312,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463441 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,441 | train | mutant | 5,054,850 | 5,060,731 | 5,061,516 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188A | L188A | 1 | 1 | 0 | 0 | 188 | L | A | 9 | CONSERVATION | null | false | false | null | null | 5,441,358 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.670863 | 0.092472 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875398,"numValue":-0.670863380721201,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875399,"numValue":0.0924721526776287,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463442 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,442 | train | mutant | 5,054,851 | 5,060,731 | 5,061,517 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188C | L188C | 1 | 1 | 0 | 0 | 188 | L | C | 9 | CONSERVATION | null | false | false | null | null | 5,441,359 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.839264 | 0.275222 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875400,"numValue":-0.839263874578709,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875401,"numValue":0.275222479295575,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463443 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,443 | train | mutant | 5,054,852 | 5,060,731 | 5,061,518 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188D | L188D | 1 | 1 | 0 | 0 | 188 | L | D | 9 | CONSERVATION | null | false | false | null | null | 5,441,360 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.819163 | 0.279457 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875402,"numValue":-0.819162884389617,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875403,"numValue":0.279456629047409,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463444 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,444 | train | mutant | 5,054,853 | 5,060,731 | 5,061,519 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188E | L188E | 1 | 1 | 0 | 0 | 188 | L | E | 9 | CONSERVATION | null | false | false | null | null | 5,441,361 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.561487 | 0.136613 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875404,"numValue":-0.561487063375454,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875405,"numValue":0.136613053704211,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463447 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,447 | train | mutant | 5,054,856 | 5,060,731 | 5,061,522 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188H | L188H | 1 | 1 | 0 | 0 | 188 | L | H | 9 | CONSERVATION | null | false | false | null | null | 5,441,364 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.610567 | 0.231889 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875410,"numValue":-0.610567433337616,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875411,"numValue":0.2318891805461,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463448 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,448 | train | mutant | 5,054,857 | 5,060,731 | 5,061,523 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188I | L188I | 1 | 1 | 0 | 0 | 188 | L | I | 9 | CONSERVATION | null | false | false | null | null | 5,441,365 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875412,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875413,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463449 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,449 | train | mutant | 5,054,858 | 5,060,731 | 5,061,524 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188K | L188K | 1 | 1 | 0 | 0 | 188 | L | K | 9 | CONSERVATION | null | false | false | null | null | 5,441,366 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.944229 | 0.386517 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875414,"numValue":-0.944228508858389,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875415,"numValue":0.386516764259657,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463450 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,450 | train | mutant | 5,054,979 | 5,060,731 | 5,061,645 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188M | L188M | 1 | 1 | 0 | 0 | 188 | L | M | 9 | CONSERVATION | null | false | false | null | null | 5,441,487 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.646711 | 0.228261 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875656,"numValue":-0.646711226638936,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875657,"numValue":0.228260876158127,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463452 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,452 | train | mutant | 5,054,981 | 5,060,731 | 5,061,647 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188P | L188P | 1 | 1 | 0 | 0 | 188 | L | P | 9 | CONSERVATION | null | false | false | null | null | 5,441,489 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.694851 | 0.10133 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875660,"numValue":-0.694850809222398,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875661,"numValue":0.101329600404791,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463453 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,453 | train | mutant | 5,054,982 | 5,060,731 | 5,061,648 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188Q | L188Q | 1 | 1 | 0 | 0 | 188 | L | Q | 9 | CONSERVATION | null | false | false | null | null | 5,441,490 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.651198 | 0.127848 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875662,"numValue":-0.651198466392071,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875663,"numValue":0.127848184307494,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463455 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,455 | train | mutant | 5,054,984 | 5,060,731 | 5,061,650 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188S | L188S | 1 | 1 | 0 | 0 | 188 | L | S | 9 | CONSERVATION | null | false | false | null | null | 5,441,492 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.669005 | 0.088675 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875666,"numValue":-0.669004918622849,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875667,"numValue":0.0886746534098754,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463456 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,456 | train | mutant | 5,054,985 | 5,060,731 | 5,061,651 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188T | L188T | 1 | 1 | 0 | 0 | 188 | L | T | 9 | CONSERVATION | null | false | false | null | null | 5,441,493 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.92405 | 0.352266 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875668,"numValue":-0.924050225340445,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875669,"numValue":0.352265718962516,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463457 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,457 | train | mutant | 5,054,986 | 5,060,731 | 5,061,652 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188V | L188V | 1 | 1 | 0 | 0 | 188 | L | V | 9 | CONSERVATION | null | false | false | null | null | 5,441,494 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.407668 | 0.076641 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875670,"numValue":-0.407668167340121,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875671,"numValue":0.0766410027829365,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463458 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,458 | train | mutant | 5,054,987 | 5,060,731 | 5,061,653 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188W | L188W | 1 | 1 | 0 | 0 | 188 | L | W | 9 | CONSERVATION | null | false | false | null | null | 5,441,495 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.867534 | 0.121496 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875672,"numValue":-0.867534366113777,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875673,"numValue":0.121495842355065,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463459 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,459 | train | mutant | 5,054,988 | 5,060,731 | 5,061,654 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L188Y | L188Y | 1 | 1 | 0 | 0 | 188 | L | Y | 9 | CONSERVATION | null | false | false | null | null | 5,441,496 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.706859 | 0.689693 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875674,"numValue":-0.706858665611061,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875675,"numValue":0.689692600038468,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462421,"numValue":9.0,"position":188,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463460 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,460 | train | mutant | 5,054,859 | 5,060,731 | 5,061,525 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delV189 | delV189 | 1 | 0 | 1 | 0 | 189 | V | - | 8 | CONSERVATION | null | false | false | null | null | 5,441,367 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.815465 | 0.218325 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875416,"numValue":-0.815465050483123,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875417,"numValue":0.218324858957712,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463461 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,461 | train | mutant | 5,054,860 | 5,060,731 | 5,061,526 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189A | V189A | 1 | 1 | 0 | 0 | 189 | V | A | 8 | CONSERVATION | null | false | false | null | null | 5,441,368 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.698215 | 0.080442 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875418,"numValue":-0.698214658820919,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875419,"numValue":0.0804415028655387,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463462 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,462 | train | mutant | 5,054,861 | 5,060,731 | 5,061,527 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189C | V189C | 1 | 1 | 0 | 0 | 189 | V | C | 8 | CONSERVATION | null | false | false | null | null | 5,441,369 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.49717 | 0.154943 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875420,"numValue":-0.497169960247184,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875421,"numValue":0.154942669272693,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463463 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,463 | train | mutant | 5,054,862 | 5,060,731 | 5,061,528 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189D | V189D | 1 | 1 | 0 | 0 | 189 | V | D | 8 | CONSERVATION | null | false | false | null | null | 5,441,370 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.312137 | 0.116543 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875422,"numValue":-0.312137290471695,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875423,"numValue":0.116542901676226,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463464 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,464 | train | mutant | 5,054,863 | 5,060,731 | 5,061,529 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189E | V189E | 1 | 1 | 0 | 0 | 189 | V | E | 8 | CONSERVATION | null | false | false | null | null | 5,441,371 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.837945 | 0.166528 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875424,"numValue":-0.83794541868949,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875425,"numValue":0.1665283046274,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463465 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,465 | train | mutant | 5,054,864 | 5,060,731 | 5,061,530 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189F | V189F | 1 | 1 | 0 | 0 | 189 | V | F | 8 | CONSERVATION | null | false | false | null | null | 5,441,372 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.636525 | 0.205829 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875426,"numValue":-0.636524545627948,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875427,"numValue":0.205828572067043,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463466 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,466 | train | mutant | 5,054,865 | 5,060,731 | 5,061,531 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189G | V189G | 1 | 1 | 0 | 0 | 189 | V | G | 8 | CONSERVATION | null | false | false | null | null | 5,441,373 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.586899 | 0.074998 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875428,"numValue":-0.586898985070148,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875429,"numValue":0.0749982801180853,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463467 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,467 | train | mutant | 5,054,866 | 5,060,731 | 5,061,532 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189H | V189H | 1 | 1 | 0 | 0 | 189 | V | H | 8 | CONSERVATION | null | false | false | null | null | 5,441,374 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.959426 | 0.353147 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875430,"numValue":-0.959425822809864,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875431,"numValue":0.353147000821234,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463468 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,468 | train | mutant | 5,054,867 | 5,060,731 | 5,061,533 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189I | V189I | 1 | 1 | 0 | 0 | 189 | V | I | 8 | CONSERVATION | null | false | false | null | null | 5,441,375 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.056049 | 0.092025 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875432,"numValue":-0.0560494751367326,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875433,"numValue":0.0920250312651388,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463469 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,469 | train | mutant | 5,054,868 | 5,060,731 | 5,061,534 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189K | V189K | 1 | 1 | 0 | 0 | 189 | V | K | 8 | CONSERVATION | null | false | false | null | null | 5,441,376 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.597632 | 0.173374 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875434,"numValue":-0.597632005925013,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875435,"numValue":0.173373674074795,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463470 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,470 | train | mutant | 5,054,869 | 5,060,731 | 5,061,535 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189L | V189L | 1 | 1 | 0 | 0 | 189 | V | L | 8 | CONSERVATION | null | false | false | null | null | 5,441,377 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.270316 | 0.072298 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875436,"numValue":-0.270316147017581,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875437,"numValue":0.0722981213781721,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463472 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,472 | train | mutant | 5,054,871 | 5,060,731 | 5,061,537 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189N | V189N | 1 | 1 | 0 | 0 | 189 | V | N | 8 | CONSERVATION | null | false | false | null | null | 5,441,379 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875440,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875441,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463473 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,473 | train | mutant | 5,054,872 | 5,060,731 | 5,061,538 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189P | V189P | 1 | 1 | 0 | 0 | 189 | V | P | 8 | CONSERVATION | null | false | false | null | null | 5,441,380 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.632053 | 0.101207 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875442,"numValue":-0.632053395350174,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875443,"numValue":0.101207460855727,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463474 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,474 | train | mutant | 5,054,873 | 5,060,731 | 5,061,539 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189Q | V189Q | 1 | 1 | 0 | 0 | 189 | V | Q | 8 | CONSERVATION | null | false | false | null | null | 5,441,381 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.951701 | 0.291904 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875444,"numValue":-0.951701284843571,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875445,"numValue":0.291903945193628,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463475 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,475 | train | mutant | 5,054,874 | 5,060,731 | 5,061,540 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189R | V189R | 1 | 1 | 0 | 0 | 189 | V | R | 8 | CONSERVATION | null | false | false | null | null | 5,441,382 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.920026 | 0.131367 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875446,"numValue":-0.920026113473898,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875447,"numValue":0.131366799335671,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463476 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,476 | train | mutant | 5,054,875 | 5,060,731 | 5,061,541 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189S | V189S | 1 | 1 | 0 | 0 | 189 | V | S | 8 | CONSERVATION | null | false | false | null | null | 5,441,383 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.049112 | 0.254087 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875448,"numValue":-1.0491121977537,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875449,"numValue":0.254087421078969,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463477 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,477 | train | mutant | 5,054,876 | 5,060,731 | 5,061,542 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189T | V189T | 1 | 1 | 0 | 0 | 189 | V | T | 8 | CONSERVATION | null | false | false | null | null | 5,441,384 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.558077 | 0.124726 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875450,"numValue":-0.558076796917461,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875451,"numValue":0.124725676839376,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463478 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,478 | train | mutant | 5,054,977 | 5,060,731 | 5,061,643 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189W | V189W | 1 | 1 | 0 | 0 | 189 | V | W | 8 | CONSERVATION | null | false | false | null | null | 5,441,485 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.611139 | 0.196819 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875652,"numValue":-0.611138545865779,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875653,"numValue":0.196819040489452,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463479 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,479 | train | mutant | 5,054,978 | 5,060,731 | 5,061,644 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V189Y | V189Y | 1 | 1 | 0 | 0 | 189 | V | Y | 8 | CONSERVATION | null | false | false | null | null | 5,441,486 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.537623 | 0.2116 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875654,"numValue":-0.537623242907183,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875655,"numValue":0.211600096728394,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462422,"numValue":8.0,"position":189,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463480 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,480 | train | mutant | 5,054,877 | 5,060,731 | 5,061,543 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delE190 | delE190 | 1 | 0 | 1 | 0 | 190 | E | - | 4 | CONSERVATION | null | false | false | null | null | 5,441,385 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.561859 | 0.288614 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875452,"numValue":-0.561858781333974,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875453,"numValue":0.288613519788219,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463481 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,481 | train | mutant | 5,054,878 | 5,060,731 | 5,061,544 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190A | E190A | 1 | 1 | 0 | 0 | 190 | E | A | 4 | CONSERVATION | null | false | false | null | null | 5,441,386 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.20899 | 0.068615 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875454,"numValue":-0.208990153975321,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875455,"numValue":0.0686147807689269,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463482 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,482 | train | mutant | 5,054,879 | 5,060,731 | 5,061,545 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190C | E190C | 1 | 1 | 0 | 0 | 190 | E | C | 4 | CONSERVATION | null | false | false | null | null | 5,441,387 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.616021 | 0.182604 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875456,"numValue":-0.61602099931923,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875457,"numValue":0.182604052855842,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463483 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,483 | train | mutant | 5,054,880 | 5,060,731 | 5,061,546 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190D | E190D | 1 | 1 | 0 | 0 | 190 | E | D | 4 | CONSERVATION | null | false | false | null | null | 5,441,388 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.1153 | 0.108111 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875458,"numValue":-0.115299606621904,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875459,"numValue":0.108110995033492,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463484 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,484 | train | mutant | 5,054,961 | 5,060,731 | 5,061,627 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190F | E190F | 1 | 1 | 0 | 0 | 190 | E | F | 4 | CONSERVATION | null | false | false | null | null | 5,441,469 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.147324 | 0.224392 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875620,"numValue":-0.147324047301142,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875621,"numValue":0.224392059652368,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463485 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,485 | train | mutant | 5,054,962 | 5,060,731 | 5,061,628 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190G | E190G | 1 | 1 | 0 | 0 | 190 | E | G | 4 | CONSERVATION | null | false | false | null | null | 5,441,470 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.481249 | 0.049391 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875622,"numValue":-0.481248658212775,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875623,"numValue":0.0493910245308633,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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