row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:5463486 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,486 | train | mutant | 5,054,963 | 5,060,731 | 5,061,629 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190H | E190H | 1 | 1 | 0 | 0 | 190 | E | H | 4 | CONSERVATION | null | false | false | null | null | 5,441,471 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.364912 | 0.192669 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875624,"numValue":-0.36491217428988,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875625,"numValue":0.192669296636134,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463487 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,487 | train | mutant | 5,054,964 | 5,060,731 | 5,061,630 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190I | E190I | 1 | 1 | 0 | 0 | 190 | E | I | 4 | CONSERVATION | null | false | false | null | null | 5,441,472 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.478656 | 0.180733 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875626,"numValue":-0.47865633726605,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875627,"numValue":0.180732885179726,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463489 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,489 | train | mutant | 5,054,966 | 5,060,731 | 5,061,632 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190L | E190L | 1 | 1 | 0 | 0 | 190 | E | L | 4 | CONSERVATION | null | false | false | null | null | 5,441,474 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.427608 | 0.080232 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875630,"numValue":-0.427607879692863,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875631,"numValue":0.0802319566031095,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463490 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,490 | train | mutant | 5,054,967 | 5,060,731 | 5,061,633 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190M | E190M | 1 | 1 | 0 | 0 | 190 | E | M | 4 | CONSERVATION | null | false | false | null | null | 5,441,475 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.243659 | 0.137572 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875632,"numValue":-0.243658504077836,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875633,"numValue":0.137571973666254,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463492 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,492 | train | mutant | 5,054,969 | 5,060,731 | 5,061,635 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190P | E190P | 1 | 1 | 0 | 0 | 190 | E | P | 4 | CONSERVATION | null | false | false | null | null | 5,441,477 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.660213 | 0.14446 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875636,"numValue":-0.660212658809746,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875637,"numValue":0.144459992992778,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463493 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,493 | train | mutant | 5,054,970 | 5,060,731 | 5,061,636 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190Q | E190Q | 1 | 1 | 0 | 0 | 190 | E | Q | 4 | CONSERVATION | null | false | false | null | null | 5,441,478 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.124335 | 0.05683 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875638,"numValue":-0.124334613202149,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875639,"numValue":0.0568295720726293,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463496 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,496 | train | mutant | 5,054,973 | 5,060,731 | 5,061,639 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190T | E190T | 1 | 1 | 0 | 0 | 190 | E | T | 4 | CONSERVATION | null | false | false | null | null | 5,441,481 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.630182 | 0.194069 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875644,"numValue":-0.630182163826933,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875645,"numValue":0.194069080992472,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463497 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,497 | train | mutant | 5,054,974 | 5,060,731 | 5,061,640 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190V | E190V | 1 | 1 | 0 | 0 | 190 | E | V | 4 | CONSERVATION | null | false | false | null | null | 5,441,482 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.658219 | 0.080337 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875646,"numValue":-0.658219160043193,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875647,"numValue":0.0803371766641953,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463498 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,498 | train | mutant | 5,054,975 | 5,060,731 | 5,061,641 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190W | E190W | 1 | 1 | 0 | 0 | 190 | E | W | 4 | CONSERVATION | null | false | false | null | null | 5,441,483 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.398692 | 0.092285 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875648,"numValue":-0.398692091655739,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875649,"numValue":0.0922850806030042,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463499 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,499 | train | mutant | 5,054,976 | 5,060,731 | 5,061,642 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E190Y | E190Y | 1 | 1 | 0 | 0 | 190 | E | Y | 4 | CONSERVATION | null | false | false | null | null | 5,441,484 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.490532 | 0.137466 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875650,"numValue":-0.490532030107111,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875651,"numValue":0.137466370522421,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462423,"numValue":4.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463500 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,500 | train | mutant | 5,054,881 | 5,060,731 | 5,061,547 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delD191 | delD191 | 1 | 0 | 1 | 0 | 191 | D | - | 8 | CONSERVATION | null | false | false | null | null | 5,441,389 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.89781 | 0.213938 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875460,"numValue":-0.897810226234305,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875461,"numValue":0.213938242272702,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463501 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,501 | train | mutant | 5,054,882 | 5,060,731 | 5,061,548 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191A | D191A | 1 | 1 | 0 | 0 | 191 | D | A | 8 | CONSERVATION | null | false | false | null | null | 5,441,390 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.286359 | 0.085327 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875462,"numValue":-0.286358886282685,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875463,"numValue":0.0853270209809632,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463502 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,502 | train | mutant | 5,054,883 | 5,060,731 | 5,061,549 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191C | D191C | 1 | 1 | 0 | 0 | 191 | D | C | 8 | CONSERVATION | null | false | false | null | null | 5,441,391 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.123547 | 0.114343 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875464,"numValue":-0.123546739686495,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875465,"numValue":0.114343240544839,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463503 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,503 | train | mutant | 5,054,944 | 5,060,731 | 5,061,610 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191E | D191E | 1 | 1 | 0 | 0 | 191 | D | E | 8 | CONSERVATION | null | false | false | null | null | 5,441,452 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.0451 | 0.094488 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875586,"numValue":-0.045099693294376,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875587,"numValue":0.0944882533262357,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463505 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,505 | train | mutant | 5,054,946 | 5,060,731 | 5,061,612 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191G | D191G | 1 | 1 | 0 | 0 | 191 | D | G | 8 | CONSERVATION | null | false | false | null | null | 5,441,454 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.228174 | 0.057981 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875590,"numValue":-0.228173660986135,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875591,"numValue":0.0579806399556901,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463506 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,506 | train | mutant | 5,054,947 | 5,060,731 | 5,061,613 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191H | D191H | 1 | 1 | 0 | 0 | 191 | D | H | 8 | CONSERVATION | null | false | false | null | null | 5,441,455 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.033786 | 0.119968 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875592,"numValue":-0.0337859828426815,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875593,"numValue":0.119968236055589,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463507 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,507 | train | mutant | 5,054,948 | 5,060,731 | 5,061,614 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191I | D191I | 1 | 1 | 0 | 0 | 191 | D | I | 8 | CONSERVATION | null | false | false | null | null | 5,441,456 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.186036 | 0.184787 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875594,"numValue":-0.186035835794773,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875595,"numValue":0.184787049887749,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463508 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,508 | train | mutant | 5,054,949 | 5,060,731 | 5,061,615 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191K | D191K | 1 | 1 | 0 | 0 | 191 | D | K | 8 | CONSERVATION | null | false | false | null | null | 5,441,457 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.302839 | 0.073462 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875596,"numValue":-0.302839169891612,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875597,"numValue":0.073462245998182,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463509 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,509 | train | mutant | 5,054,950 | 5,060,731 | 5,061,616 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191L | D191L | 1 | 1 | 0 | 0 | 191 | D | L | 8 | CONSERVATION | null | false | false | null | null | 5,441,458 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.167378 | 0.042529 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875598,"numValue":-0.167378429089388,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875599,"numValue":0.0425291761406488,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463511 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,511 | train | mutant | 5,054,952 | 5,060,731 | 5,061,618 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191N | D191N | 1 | 1 | 0 | 0 | 191 | D | N | 8 | CONSERVATION | null | false | false | null | null | 5,441,460 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.29142 | 0.097845 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875602,"numValue":-0.291419537060462,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875603,"numValue":0.0978452712824413,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463512 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,512 | train | mutant | 5,054,953 | 5,060,731 | 5,061,619 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191P | D191P | 1 | 1 | 0 | 0 | 191 | D | P | 8 | CONSERVATION | null | false | false | null | null | 5,441,461 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.687139 | 0.102979 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875604,"numValue":-0.687138970449157,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875605,"numValue":0.102978516240713,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463513 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,513 | train | mutant | 5,054,954 | 5,060,731 | 5,061,620 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191Q | D191Q | 1 | 1 | 0 | 0 | 191 | D | Q | 8 | CONSERVATION | null | false | false | null | null | 5,441,462 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.137397 | 0.060334 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875606,"numValue":-0.137397096392398,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875607,"numValue":0.0603339300379172,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463515 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,515 | train | mutant | 5,054,956 | 5,060,731 | 5,061,622 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191S | D191S | 1 | 1 | 0 | 0 | 191 | D | S | 8 | CONSERVATION | null | false | false | null | null | 5,441,464 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.118698 | 0.041454 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875610,"numValue":-0.11869755058488,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875611,"numValue":0.0414538117930427,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463516 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,516 | train | mutant | 5,054,957 | 5,060,731 | 5,061,623 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191T | D191T | 1 | 1 | 0 | 0 | 191 | D | T | 8 | CONSERVATION | null | false | false | null | null | 5,441,465 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.339851 | 0.083442 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875612,"numValue":-0.339850517919893,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875613,"numValue":0.0834420623259667,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463517 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,517 | train | mutant | 5,054,958 | 5,060,731 | 5,061,624 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191V | D191V | 1 | 1 | 0 | 0 | 191 | D | V | 8 | CONSERVATION | null | false | false | null | null | 5,441,466 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.449974 | 0.082851 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875614,"numValue":-0.449974102010147,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875615,"numValue":0.0828514125777239,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463518 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,518 | train | mutant | 5,054,959 | 5,060,731 | 5,061,625 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191W | D191W | 1 | 1 | 0 | 0 | 191 | D | W | 8 | CONSERVATION | null | false | false | null | null | 5,441,467 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.140994 | 0.060094 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875616,"numValue":-0.140993604912398,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875617,"numValue":0.0600941904703378,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463519 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,519 | train | mutant | 5,054,960 | 5,060,731 | 5,061,626 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D191Y | D191Y | 1 | 1 | 0 | 0 | 191 | D | Y | 8 | CONSERVATION | null | false | false | null | null | 5,441,468 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.218318 | 0.112963 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875618,"numValue":-0.218318218856769,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875619,"numValue":0.11296267417296,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462424,"numValue":8.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463520 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,520 | train | mutant | 5,054,884 | 5,060,731 | 5,061,550 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delL192 | delL192 | 1 | 0 | 1 | 0 | 192 | L | - | 9 | CONSERVATION | null | false | false | null | null | 5,441,392 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.753049 | 0.194454 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875466,"numValue":-0.753048548555339,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875467,"numValue":0.194454143000001,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463521 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,521 | train | mutant | 5,054,885 | 5,060,731 | 5,061,551 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192A | L192A | 1 | 1 | 0 | 0 | 192 | L | A | 9 | CONSERVATION | null | false | false | null | null | 5,441,393 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.726405 | 0.108837 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875468,"numValue":-0.72640463274735,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875469,"numValue":0.108836936838434,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463523 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,523 | train | mutant | 5,054,887 | 5,060,731 | 5,061,553 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192D | L192D | 1 | 1 | 0 | 0 | 192 | L | D | 9 | CONSERVATION | null | false | false | null | null | 5,441,395 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.507701 | 0.230204 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875472,"numValue":-0.507701032647429,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875473,"numValue":0.230203552613622,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463524 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,524 | train | mutant | 5,054,888 | 5,060,731 | 5,061,554 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192E | L192E | 1 | 1 | 0 | 0 | 192 | L | E | 9 | CONSERVATION | null | false | false | null | null | 5,441,396 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.773576 | 0.178797 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875474,"numValue":-0.7735759736886,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875475,"numValue":0.17879723190792,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463525 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,525 | train | mutant | 5,054,889 | 5,060,731 | 5,061,555 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192F | L192F | 1 | 1 | 0 | 0 | 192 | L | F | 9 | CONSERVATION | null | false | false | null | null | 5,441,397 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.678301 | 0.161235 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875476,"numValue":-0.678301187636324,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875477,"numValue":0.161235441858015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463526 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,526 | train | mutant | 5,054,890 | 5,060,731 | 5,061,556 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192G | L192G | 1 | 1 | 0 | 0 | 192 | L | G | 9 | CONSERVATION | null | false | false | null | null | 5,441,398 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.882428 | 0.107688 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875478,"numValue":-0.882427505979682,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875479,"numValue":0.107688199375416,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463527 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,527 | train | mutant | 5,054,891 | 5,060,731 | 5,061,557 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192H | L192H | 1 | 1 | 0 | 0 | 192 | L | H | 9 | CONSERVATION | null | false | false | null | null | 5,441,399 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875480,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875481,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463528 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,528 | train | mutant | 5,054,892 | 5,060,731 | 5,061,558 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192I | L192I | 1 | 1 | 0 | 0 | 192 | L | I | 9 | CONSERVATION | null | false | false | null | null | 5,441,400 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.454741 | 0.242735 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875482,"numValue":-0.454740864474103,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875483,"numValue":0.242735274658358,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463529 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,529 | train | mutant | 5,054,893 | 5,060,731 | 5,061,559 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192K | L192K | 1 | 1 | 0 | 0 | 192 | L | K | 9 | CONSERVATION | null | false | false | null | null | 5,441,401 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.856679 | 0.203644 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875484,"numValue":-0.856679410020647,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875485,"numValue":0.203643659621403,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463530 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,530 | train | mutant | 5,054,934 | 5,060,731 | 5,061,600 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192M | L192M | 1 | 1 | 0 | 0 | 192 | L | M | 9 | CONSERVATION | null | false | false | null | null | 5,441,442 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.66751 | 0.18901 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875566,"numValue":-0.667510321286711,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875567,"numValue":0.18901009023993,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463531 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,531 | train | mutant | 5,054,935 | 5,060,731 | 5,061,601 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192N | L192N | 1 | 1 | 0 | 0 | 192 | L | N | 9 | CONSERVATION | null | false | false | null | null | 5,441,443 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.688474 | 0.379456 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875568,"numValue":-0.688473503044311,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875569,"numValue":0.379455527684512,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463533 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,533 | train | mutant | 5,054,937 | 5,060,731 | 5,061,603 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192Q | L192Q | 1 | 1 | 0 | 0 | 192 | L | Q | 9 | CONSERVATION | null | false | false | null | null | 5,441,445 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.705854 | 0.173576 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875572,"numValue":-0.705853775719417,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875573,"numValue":0.173576005612162,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463534 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,534 | train | mutant | 5,054,938 | 5,060,731 | 5,061,604 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192R | L192R | 1 | 1 | 0 | 0 | 192 | L | R | 9 | CONSERVATION | null | false | false | null | null | 5,441,446 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.750869 | 0.074268 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875574,"numValue":-0.750868616185406,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875575,"numValue":0.0742678690144318,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463535 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,535 | train | mutant | 5,054,939 | 5,060,731 | 5,061,605 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192S | L192S | 1 | 1 | 0 | 0 | 192 | L | S | 9 | CONSERVATION | null | false | false | null | null | 5,441,447 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.913593 | 0.141412 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875576,"numValue":-0.913592826137097,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875577,"numValue":0.14141173973039,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463536 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,536 | train | mutant | 5,054,940 | 5,060,731 | 5,061,606 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192T | L192T | 1 | 1 | 0 | 0 | 192 | L | T | 9 | CONSERVATION | null | false | false | null | null | 5,441,448 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.848311 | 0.246549 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875578,"numValue":-0.848311222808108,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875579,"numValue":0.246548735707223,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463537 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,537 | train | mutant | 5,054,941 | 5,060,731 | 5,061,607 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192V | L192V | 1 | 1 | 0 | 0 | 192 | L | V | 9 | CONSERVATION | null | false | false | null | null | 5,441,449 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.775499 | 0.147905 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875580,"numValue":-0.775498729841268,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875581,"numValue":0.147904992286469,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463538 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,538 | train | mutant | 5,054,942 | 5,060,731 | 5,061,608 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192W | L192W | 1 | 1 | 0 | 0 | 192 | L | W | 9 | CONSERVATION | null | false | false | null | null | 5,441,450 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.057676 | 0.217716 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875582,"numValue":-1.05767626794403,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875583,"numValue":0.217715757390504,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463539 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,539 | train | mutant | 5,054,943 | 5,060,731 | 5,061,609 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L192Y | L192Y | 1 | 1 | 0 | 0 | 192 | L | Y | 9 | CONSERVATION | null | false | false | null | null | 5,441,451 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.886235 | 0.179937 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875584,"numValue":-0.886234503784139,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875585,"numValue":0.179936839232143,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462425,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463540 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,540 | train | mutant | 5,054,894 | 5,060,731 | 5,061,560 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delE193 | delE193 | 1 | 0 | 1 | 0 | 193 | E | - | 8 | CONSERVATION | null | false | false | null | null | 5,441,402 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.225467 | 0.180059 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875486,"numValue":-0.225467181380902,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875487,"numValue":0.18005859569846,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463541 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,541 | train | mutant | 5,054,895 | 5,060,731 | 5,061,561 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193A | E193A | 1 | 1 | 0 | 0 | 193 | E | A | 8 | CONSERVATION | null | false | false | null | null | 5,441,403 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.282739 | 0.079306 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875488,"numValue":-0.282738818173765,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875489,"numValue":0.0793059179101559,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463542 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,542 | train | mutant | 5,054,896 | 5,060,731 | 5,061,562 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193C | E193C | 1 | 1 | 0 | 0 | 193 | E | C | 8 | CONSERVATION | null | false | false | null | null | 5,441,404 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.346987 | 0.078989 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875490,"numValue":-0.346987221796131,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875491,"numValue":0.0789885977016631,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463543 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,543 | train | mutant | 5,054,897 | 5,060,731 | 5,061,563 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193D | E193D | 1 | 1 | 0 | 0 | 193 | E | D | 8 | CONSERVATION | null | false | false | null | null | 5,441,405 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.165001 | 0.087857 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875492,"numValue":-0.165001400646292,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875493,"numValue":0.0878570909813542,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463545 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,545 | train | mutant | 5,054,919 | 5,060,731 | 5,061,585 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193G | E193G | 1 | 1 | 0 | 0 | 193 | E | G | 8 | CONSERVATION | null | false | false | null | null | 5,441,427 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.316775 | 0.053045 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875536,"numValue":-0.316774890202898,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875537,"numValue":0.0530451359265375,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463546 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,546 | train | mutant | 5,054,920 | 5,060,731 | 5,061,586 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193H | E193H | 1 | 1 | 0 | 0 | 193 | E | H | 8 | CONSERVATION | null | false | false | null | null | 5,441,428 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.017635 | 0.342048 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875538,"numValue":0.017634575771772,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875539,"numValue":0.342048263637546,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463547 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,547 | train | mutant | 5,054,921 | 5,060,731 | 5,061,587 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193I | E193I | 1 | 1 | 0 | 0 | 193 | E | I | 8 | CONSERVATION | null | false | false | null | null | 5,441,429 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.240093 | 0.30956 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875540,"numValue":-0.240093280648814,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875541,"numValue":0.309560228987712,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463548 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,548 | train | mutant | 5,054,922 | 5,060,731 | 5,061,588 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193K | E193K | 1 | 1 | 0 | 0 | 193 | E | K | 8 | CONSERVATION | null | false | false | null | null | 5,441,430 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.750863 | 0.207692 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875542,"numValue":-0.750863125332703,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875543,"numValue":0.207691822699728,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463550 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,550 | train | mutant | 5,054,924 | 5,060,731 | 5,061,590 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193M | E193M | 1 | 1 | 0 | 0 | 193 | E | M | 8 | CONSERVATION | null | false | false | null | null | 5,441,432 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.325488 | 0.135773 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875546,"numValue":-0.325488107275938,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875547,"numValue":0.135772570158014,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463552 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,552 | train | mutant | 5,054,926 | 5,060,731 | 5,061,592 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193P | E193P | 1 | 1 | 0 | 0 | 193 | E | P | 8 | CONSERVATION | null | false | false | null | null | 5,441,434 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.46704 | 0.102066 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875550,"numValue":-0.467040438374356,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875551,"numValue":0.102066013138142,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463553 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,553 | train | mutant | 5,054,927 | 5,060,731 | 5,061,593 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193Q | E193Q | 1 | 1 | 0 | 0 | 193 | E | Q | 8 | CONSERVATION | null | false | false | null | null | 5,441,435 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.114558 | 0.083566 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875552,"numValue":-0.114557703035851,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875553,"numValue":0.0835663726772616,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463554 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,554 | train | mutant | 5,054,928 | 5,060,731 | 5,061,594 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193R | E193R | 1 | 1 | 0 | 0 | 193 | E | R | 8 | CONSERVATION | null | false | false | null | null | 5,441,436 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.460973 | 0.054071 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875554,"numValue":-0.460973046138326,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875555,"numValue":0.0540711719857972,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463555 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,555 | train | mutant | 5,054,929 | 5,060,731 | 5,061,595 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193S | E193S | 1 | 1 | 0 | 0 | 193 | E | S | 8 | CONSERVATION | null | false | false | null | null | 5,441,437 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.204453 | 0.058046 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875556,"numValue":-0.204452538840999,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875557,"numValue":0.0580460577193967,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463556 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,556 | train | mutant | 5,054,930 | 5,060,731 | 5,061,596 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193T | E193T | 1 | 1 | 0 | 0 | 193 | E | T | 8 | CONSERVATION | null | false | false | null | null | 5,441,438 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.172168 | 0.139601 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875558,"numValue":-0.172168240365269,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875559,"numValue":0.139600652198376,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463557 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,557 | train | mutant | 5,054,931 | 5,060,731 | 5,061,597 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193V | E193V | 1 | 1 | 0 | 0 | 193 | E | V | 8 | CONSERVATION | null | false | false | null | null | 5,441,439 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.409232 | 0.066863 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875560,"numValue":-0.409232421889029,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875561,"numValue":0.0668633902982698,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463559 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,559 | train | mutant | 5,054,933 | 5,060,731 | 5,061,599 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E193Y | E193Y | 1 | 1 | 0 | 0 | 193 | E | Y | 8 | CONSERVATION | null | false | false | null | null | 5,441,441 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.531675 | 0.151285 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875564,"numValue":-0.531675372488114,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875565,"numValue":0.151284612124729,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462426,"numValue":8.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463560 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,560 | train | mutant | 5,054,898 | 5,060,731 | 5,061,564 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delR194 | delR194 | 1 | 0 | 1 | 0 | 194 | R | - | 4 | CONSERVATION | null | false | false | null | null | 5,441,406 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875494,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875495,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463561 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,561 | train | mutant | 5,054,899 | 5,060,731 | 5,061,565 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194A | R194A | 1 | 1 | 0 | 0 | 194 | R | A | 4 | CONSERVATION | null | false | false | null | null | 5,441,407 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875496,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875497,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463562 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,562 | train | mutant | 5,054,900 | 5,060,731 | 5,061,566 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194C | R194C | 1 | 1 | 0 | 0 | 194 | R | C | 4 | CONSERVATION | null | false | false | null | null | 5,441,408 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875498,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875499,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463563 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,563 | train | mutant | 5,054,901 | 5,060,731 | 5,061,567 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194D | R194D | 1 | 1 | 0 | 0 | 194 | R | D | 4 | CONSERVATION | null | false | false | null | null | 5,441,409 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875500,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875501,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463565 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,565 | train | mutant | 5,054,903 | 5,060,731 | 5,061,569 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194F | R194F | 1 | 1 | 0 | 0 | 194 | R | F | 4 | CONSERVATION | null | false | false | null | null | 5,441,411 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875504,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875505,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463566 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,566 | train | mutant | 5,054,904 | 5,060,731 | 5,061,570 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194G | R194G | 1 | 1 | 0 | 0 | 194 | R | G | 4 | CONSERVATION | null | false | false | null | null | 5,441,412 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875506,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875507,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463567 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,567 | train | mutant | 5,054,905 | 5,060,731 | 5,061,571 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194H | R194H | 1 | 1 | 0 | 0 | 194 | R | H | 4 | CONSERVATION | null | false | false | null | null | 5,441,413 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875508,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875509,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463568 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,568 | train | mutant | 5,054,906 | 5,060,731 | 5,061,572 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194I | R194I | 1 | 1 | 0 | 0 | 194 | R | I | 4 | CONSERVATION | null | false | false | null | null | 5,441,414 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875510,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875511,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463569 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,569 | train | mutant | 5,054,907 | 5,060,731 | 5,061,573 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194K | R194K | 1 | 1 | 0 | 0 | 194 | R | K | 4 | CONSERVATION | null | false | false | null | null | 5,441,415 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875512,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875513,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463570 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,570 | train | mutant | 5,054,908 | 5,060,731 | 5,061,574 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194L | R194L | 1 | 1 | 0 | 0 | 194 | R | L | 4 | CONSERVATION | null | false | false | null | null | 5,441,416 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875514,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875515,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463571 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,571 | train | mutant | 5,054,909 | 5,060,731 | 5,061,575 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194M | R194M | 1 | 1 | 0 | 0 | 194 | R | M | 4 | CONSERVATION | null | false | false | null | null | 5,441,417 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875516,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875517,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463572 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,572 | train | mutant | 5,054,910 | 5,060,731 | 5,061,576 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194N | R194N | 1 | 1 | 0 | 0 | 194 | R | N | 4 | CONSERVATION | null | false | false | null | null | 5,441,418 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875518,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875519,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463573 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,573 | train | mutant | 5,054,911 | 5,060,731 | 5,061,577 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194P | R194P | 1 | 1 | 0 | 0 | 194 | R | P | 4 | CONSERVATION | null | false | false | null | null | 5,441,419 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875520,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875521,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463574 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,574 | train | mutant | 5,054,912 | 5,060,731 | 5,061,578 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194Q | R194Q | 1 | 1 | 0 | 0 | 194 | R | Q | 4 | CONSERVATION | null | false | false | null | null | 5,441,420 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875522,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875523,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463575 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,575 | train | mutant | 5,054,913 | 5,060,731 | 5,061,579 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194S | R194S | 1 | 1 | 0 | 0 | 194 | R | S | 4 | CONSERVATION | null | false | false | null | null | 5,441,421 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875524,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875525,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463576 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,576 | train | mutant | 5,054,914 | 5,060,731 | 5,061,580 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194T | R194T | 1 | 1 | 0 | 0 | 194 | R | T | 4 | CONSERVATION | null | false | false | null | null | 5,441,422 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875526,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875527,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463578 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,578 | train | mutant | 5,054,916 | 5,060,731 | 5,061,582 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194W | R194W | 1 | 1 | 0 | 0 | 194 | R | W | 4 | CONSERVATION | null | false | false | null | null | 5,441,424 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875530,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875531,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463579 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,579 | train | mutant | 5,054,917 | 5,060,731 | 5,061,583 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R194Y | R194Y | 1 | 1 | 0 | 0 | 194 | R | Y | 4 | CONSERVATION | null | false | false | null | null | 5,441,425 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12875532,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12875533,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462427,"numValue":4.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463580 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,580 | train | mutant | 5,057,412 | 5,064,078 | 5,064,079 | 508 | 507 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | delK368 | delK368 | 1 | 0 | 1 | 0 | 368 | K | - | 8 | CONSERVATION | null | false | false | null | null | 5,455,887 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12904456,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12904457,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463581 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,581 | train | mutant | 5,057,413 | 5,064,078 | 5,064,080 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368A | K368A | 1 | 1 | 0 | 0 | 368 | K | A | 8 | CONSERVATION | null | false | false | null | null | 5,455,888 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12904458,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12904459,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463582 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,582 | train | mutant | 5,057,414 | 5,064,078 | 5,064,081 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368C | K368C | 1 | 1 | 0 | 0 | 368 | K | C | 8 | CONSERVATION | null | false | false | null | null | 5,455,889 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.774696 | 0.343928 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12904460,"numValue":-0.774695969337547,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12904461,"numValue":0.34392752759922,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463583 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,583 | train | mutant | 5,057,415 | 5,064,078 | 5,064,082 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368D | K368D | 1 | 1 | 0 | 0 | 368 | K | D | 8 | CONSERVATION | null | false | false | null | null | 5,455,890 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.995423 | 0.171805 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12904462,"numValue":-0.995422810569672,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12904463,"numValue":0.171804938432445,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463584 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,584 | train | mutant | 5,057,416 | 5,064,078 | 5,064,083 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368E | K368E | 1 | 1 | 0 | 0 | 368 | K | E | 8 | CONSERVATION | null | false | false | null | null | 5,455,891 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.13616 | 0.08585 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12904464,"numValue":-0.136160467356473,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12904465,"numValue":0.0858499914365119,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463586 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,586 | train | mutant | 5,057,418 | 5,064,078 | 5,064,085 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368G | K368G | 1 | 1 | 0 | 0 | 368 | K | G | 8 | CONSERVATION | null | false | false | null | null | 5,455,893 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.572655 | 0.197477 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12904468,"numValue":-0.572655343452226,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12904469,"numValue":0.197477289649638,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463587 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,587 | train | mutant | 5,057,419 | 5,064,078 | 5,064,086 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368H | K368H | 1 | 1 | 0 | 0 | 368 | K | H | 8 | CONSERVATION | null | false | false | null | null | 5,455,894 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12904470,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12904471,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463588 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,588 | train | mutant | 5,057,420 | 5,064,078 | 5,064,087 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368I | K368I | 1 | 1 | 0 | 0 | 368 | K | I | 8 | CONSERVATION | null | false | false | null | null | 5,455,895 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12904472,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12904473,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463589 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,589 | train | mutant | 5,058,119 | 5,064,078 | 5,064,786 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368L | K368L | 1 | 1 | 0 | 0 | 368 | K | L | 8 | CONSERVATION | null | false | false | null | null | 5,456,596 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.211001 | 0.212476 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12905874,"numValue":-0.211001261278026,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12905875,"numValue":0.212476140136368,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463590 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,590 | train | mutant | 5,058,120 | 5,064,078 | 5,064,787 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368M | K368M | 1 | 1 | 0 | 0 | 368 | K | M | 8 | CONSERVATION | null | false | false | null | null | 5,456,597 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.898926 | 0.556614 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12905876,"numValue":0.898926421020791,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12905877,"numValue":0.556614149082781,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463592 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,592 | train | mutant | 5,058,122 | 5,064,078 | 5,064,789 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368P | K368P | 1 | 1 | 0 | 0 | 368 | K | P | 8 | CONSERVATION | null | false | false | null | null | 5,456,599 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.512594 | 0.714962 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12905880,"numValue":-1.51259359375953,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12905881,"numValue":0.714962369289406,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463593 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,593 | train | mutant | 5,058,123 | 5,064,078 | 5,064,790 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368Q | K368Q | 1 | 1 | 0 | 0 | 368 | K | Q | 8 | CONSERVATION | null | false | false | null | null | 5,456,600 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12905882,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12905883,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463594 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,594 | train | mutant | 5,058,124 | 5,064,078 | 5,064,791 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368R | K368R | 1 | 1 | 0 | 0 | 368 | K | R | 8 | CONSERVATION | null | false | false | null | null | 5,456,601 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12905884,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12905885,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463595 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,595 | train | mutant | 5,058,125 | 5,064,078 | 5,064,792 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368S | K368S | 1 | 1 | 0 | 0 | 368 | K | S | 8 | CONSERVATION | null | false | false | null | null | 5,456,602 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.401084 | 0.217908 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12905886,"numValue":-0.401083527786791,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12905887,"numValue":0.217908403750385,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463596 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,596 | train | mutant | 5,058,126 | 5,064,078 | 5,064,793 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368T | K368T | 1 | 1 | 0 | 0 | 368 | K | T | 8 | CONSERVATION | null | false | false | null | null | 5,456,603 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12905888,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12905889,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463597 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,597 | train | mutant | 5,058,127 | 5,064,078 | 5,064,794 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368V | K368V | 1 | 1 | 0 | 0 | 368 | K | V | 8 | CONSERVATION | null | false | false | null | null | 5,456,604 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.825342 | 0.2831 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12905890,"numValue":-0.825342477470446,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12905891,"numValue":0.283099759974116,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463598 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,598 | train | mutant | 5,058,128 | 5,064,078 | 5,064,795 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368W | K368W | 1 | 1 | 0 | 0 | 368 | K | W | 8 | CONSERVATION | null | false | false | null | null | 5,456,605 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.47344 | 0.916746 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12905892,"numValue":-1.47343987032605,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12905893,"numValue":0.916746392416795,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463599 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,599 | train | mutant | 5,058,129 | 5,064,078 | 5,064,796 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | K368Y | K368Y | 1 | 1 | 0 | 0 | 368 | K | Y | 8 | CONSERVATION | null | false | false | null | null | 5,456,606 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12905894,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12905895,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462796,"numValue":8.0,"position":368,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463600 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,600 | train | mutant | 5,057,421 | 5,064,078 | 5,064,088 | 508 | 507 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | delG369 | delG369 | 1 | 0 | 1 | 0 | 369 | G | - | 7 | CONSERVATION | null | false | false | null | null | 5,455,896 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.905102 | 0.660571 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12904474,"numValue":-1.90510155800474,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12904475,"numValue":0.660570802604454,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462797,"numValue":7.0,"position":369,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463601 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,601 | train | mutant | 5,057,422 | 5,064,078 | 5,064,089 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | G369A | G369A | 1 | 1 | 0 | 0 | 369 | G | A | 7 | CONSERVATION | null | false | false | null | null | 5,455,897 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.132672 | 0.101101 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12904476,"numValue":-0.132672011562352,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12904477,"numValue":0.101100782225835,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462797,"numValue":7.0,"position":369,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5463602 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,463,602 | train | mutant | 5,057,423 | 5,064,078 | 5,064,090 | 508 | 508 | 8,259 | Tesmin | Homo sapiens | 1 | 8259 | Tesmin | Homo sapiens | 1 | Q9Y4I5 | IPR005172|IPR028307|IPR033467 | G369C | G369C | 1 | 1 | 0 | 0 | 369 | G | C | 7 | CONSERVATION | null | false | false | null | null | 5,455,898 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.447515 | 0.353007 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12904478,"numValue":-0.447515209834977,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12904479,"numValue":0.353007240088744,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462797,"numValue":7.0,"position":369,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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