row_id
string
dataset_id
string
source_dataset
string
source_file
string
source_table
string
source_sha
string
row_index
int64
split
string
subject_type
string
entry_id
int64
sequence_id
int64
target_sequence_id
int64
source_sequence_length
int64
target_sequence_length
int64
protein_id
int64
protein_name
string
organism
string
isoform
int64
protein_ids
string
protein_names
string
organisms
string
isoforms
string
uniprot_accessions
string
interpro_accessions
string
ec_numbers
string
megascale_ids
string
other_references
string
mutations
string
substitutions
string
deletions
string
insertions
string
mutation_count
int64
substitution_count
int64
deletion_count
int64
insertion_count
int64
first_position
int64
first_source_aa
string
first_target_aa
string
conservation
float64
feature_types
string
pdb_ids
string
afdb_ids
string
structure_ids
string
structure_methods
string
structure_resolution_min
float64
residue_positions
string
residue_chain_names
string
residue_secondary_structures
string
residue_in_pocket_any
bool
residue_in_tunnel_any
bool
residue_asa_mean
float64
residue_bfactor_mean
float64
experiment_id
int64
experiment_dataset
string
ph
float64
measure
string
method
string
buffer
string
buffer_conc
string
exp_temperature
float64
ion
string
ion_conc
string
pdb_chain_mutation
string
tm
float64
dtm
float64
dg
float64
dg_text
string
ddg
float64
dh
float64
dcp
float64
dhvh
float64
cm
float64
m_value
float64
trypsin_ml
float64
chymotrypsin_ml
float64
stabilizing
float64
stabilizing_text
string
domainome_fitness
float64
domainome_fitness_std
float64
domainome_ddg
float64
domainome_ddg_std
float64
reversibility
string
state
string
measurement_types
string
measurement_datasets
string
annotation_types
string
publication_id
string
publication_type
string
publication_title
string
publication_year
int64
publication_doi
string
publication_pmid
string
publication_journal
string
publication_url
string
publication_author_count
int64
publication_authors
string
annotations_json
string
measurements_json
string
features_json
string
fireprotdb:7915
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,915
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,019
ProTherm
7
CD
GdnHCl
Sodium phosphate
50 mM
5
NaCl
150 mM
null
null
10.24
null
null
null
null
null
1.82
null
null
null
null
null
null
null
yes
DG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
1558
ARTICLE
Probing the folding mechanism of a leucine zipper peptide by stopped-flow circular dichroism spectroscopy.
1,995
10.1021/bi00039a042
7548036
Biochemistry;34;12812-9
5
Luo J|Bilsel O|Matthews C R|Jones B E|Zitzewitz J A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":5.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUF...
[{"datasets":[],"id":79748,"numValue":10.24,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":79749,"numValue":1.82,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":79750,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
fireprotdb:7916
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,916
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,093
ProTherm
7
CD
Thermal
sodium phosphate
10 mM
null
55
null
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes
TM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC
18
ARTICLE
An intrahelical salt bridge within the trigger site stabilizes the GCN4 leucine zipper.
2,001
10.1074/jbc.M010492200
11134036
J Biol Chem;276;13685-8
6
Frank S|Schulthess T|Landwehr R|Lustig A|Kammerer R A|Jaravine V A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"}]
[{"datasets":[],"id":79978,"numValue":55.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":79979,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
fireprotdb:7917
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,917
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,525
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
22
null
null
null
17.21
0.17
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":81179,"numValue":22.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81180,"numValue":17.21,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":81181,"numValue":0.17,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":81182,"numValue":4.0,"references":[]...
fireprotdb:7918
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,918
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,526
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
22.1
null
null
null
17.5
0.14
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":81184,"numValue":22.1,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81185,"numValue":17.5,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":81186,"numValue":0.14,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":81187,"numValue":4.0,"references":[],...
fireprotdb:7919
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,919
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,527
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
22
null
null
null
17.11
0.14
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":81189,"numValue":22.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81190,"numValue":17.11,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":81191,"numValue":0.14,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":81192,"numValue":4.0,"references":[]...
fireprotdb:7920
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,920
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,528
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
21.9
null
null
null
17.11
0.14
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":81194,"numValue":21.9,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81195,"numValue":17.11,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":81196,"numValue":0.14,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":81197,"numValue":4.0,"references":[]...
fireprotdb:7921
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,921
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,529
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
22.3
null
null
null
17.73
0.1
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":81199,"numValue":22.3,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81200,"numValue":17.73,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":81201,"numValue":0.1,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":81202,"numValue":4.0,"references":[],...
fireprotdb:7922
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,922
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,530
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
50.4
null
null
null
28.68
0.29
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":81204,"numValue":50.4,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81205,"numValue":28.68,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":81206,"numValue":0.29,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":81207,"numValue":4.0,"references":[]...
fireprotdb:7924
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,924
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,532
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
49
null
null
null
25.81
0.19
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":81214,"numValue":49.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81215,"numValue":25.81,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":81216,"numValue":0.19,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":81217,"numValue":4.0,"references":[]...
fireprotdb:7925
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,925
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,533
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
48.3
null
null
null
null
0.19
24.86
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DCP|DHVH|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":81219,"numValue":48.3,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81220,"numValue":0.19,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":81221,"numValue":24.86,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":81222,"numValue":4.0,"references":...
fireprotdb:7926
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,926
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,534
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
47.7
null
null
null
24.14
0.17
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":81224,"numValue":47.7,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81225,"numValue":24.14,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":81226,"numValue":0.17,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":81227,"numValue":4.0,"references":[]...
fireprotdb:7927
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,927
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,535
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
64.2
null
null
null
59.75
0.5
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":81229,"numValue":64.2,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81230,"numValue":59.75,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":81231,"numValue":0.5,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":81232,"numValue":4.0,"references":[],...
fireprotdb:7928
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,928
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,536
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
67.7
null
null
null
60.95
0.6
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":81234,"numValue":67.7,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81235,"numValue":60.95,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":81236,"numValue":0.6,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":81237,"numValue":4.0,"references":[],...
fireprotdb:7929
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,929
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,537
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
71.6
null
null
null
61.9
0.6
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":81239,"numValue":71.6,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81240,"numValue":61.9,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":81241,"numValue":0.6,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":81242,"numValue":4.0,"references":[],"...
fireprotdb:7930
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,930
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,538
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
75.2
null
null
null
62.14
0.5
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":81244,"numValue":75.2,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81245,"numValue":62.14,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":81246,"numValue":0.5,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":81247,"numValue":4.0,"references":[],...
fireprotdb:7931
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,931
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
22,539
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
77.9
null
null
null
62.14
0.41
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":81249,"numValue":77.9,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81250,"numValue":62.14,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":81251,"numValue":0.41,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":81252,"numValue":4.0,"references":[]...
fireprotdb:7932
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,932
train
sequence
128
128
-1
281
-1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
0
0
0
0
-1
null
null
false
false
null
null
27,246
ProTherm
7
CD
Urea
Sodium phosphate
50mM
15
NaCl
150 mM
null
null
10.1
null
null
null
null
null
0.94
null
null
null
null
null
null
null
Unknown
DG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
867
ARTICLE
Salt-bridges can stabilize but do not accelerate the folding of the homodimeric coiled-coil peptide GCN4-p1.
2,004
10.1016/j.jmb.2003.12.069
15037063
J Mol Biol;336;989-96
3
Matthews C Robert|Ibarra-Molero Beatriz|Zitzewitz Jill A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":15.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50mM","type":"BUFFE...
[{"datasets":[],"id":95581,"numValue":10.1,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":95582,"numValue":0.94,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":95583,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
fireprotdb:7935
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,935
train
mutant
7,358
128
8,028
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
R249V|Y265W
R249V|Y265W
2
2
0
0
249
R
V
9
CONSERVATION
2ZTA
320
null
249|265
A|B
L|H
true
true
142.395092
35.552368
15,736
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
2ZTA_A:R1V 2ZTA_A:Y17W
45.6
-3.6
null
null
22.47
0.33
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DTM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":57760,"numValue":45.6,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57761,"numValue":-3.6,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57762,"numValue":22.47,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":57763,"numValue":0.33,"references":[...
[{"id":8359,"numValue":9.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8375,"numValue":5.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7936
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,936
train
mutant
7,358
128
8,028
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
R249V|Y265W
R249V|Y265W
2
2
0
0
249
R
V
9
CONSERVATION
2ZTA
320
null
249|265
A|B
L|H
true
true
142.395092
35.552368
15,737
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
2ZTA_A:R1V 2ZTA_A:Y17W
43.5
-5.5
null
null
21.75
0.43
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DTM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":57766,"numValue":43.5,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57767,"numValue":-5.5,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57768,"numValue":21.75,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":57769,"numValue":0.43,"references":[...
[{"id":8359,"numValue":9.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8375,"numValue":5.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7937
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,937
train
mutant
7,358
128
8,028
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
R249V|Y265W
R249V|Y265W
2
2
0
0
249
R
V
9
CONSERVATION
2ZTA
320
null
249|265
A|B
L|H
true
true
142.395092
35.552368
15,741
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
2ZTA_A:R1V 2ZTA_A:Y17W
65.5
-6.1
null
null
48.76
0.69
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DTM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":57790,"numValue":65.5,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57791,"numValue":-6.1,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57792,"numValue":48.76,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":57793,"numValue":0.69,"references":[...
[{"id":8359,"numValue":9.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8375,"numValue":5.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7938
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,938
train
mutant
7,358
128
8,028
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
R249V|Y265W
R249V|Y265W
2
2
0
0
249
R
V
9
CONSERVATION
2ZTA
320
null
249|265
A|B
L|H
true
true
142.395092
35.552368
15,742
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
2ZTA_A:R1V 2ZTA_A:Y17W
65.6
-6
null
null
48.28
0.6
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DTM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":57796,"numValue":65.6,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57797,"numValue":-6.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57798,"numValue":48.28,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":57799,"numValue":0.6,"references":[]...
[{"id":8359,"numValue":9.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8375,"numValue":5.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7939
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,939
train
mutant
7,357
128
8,027
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
M250V|Y265W
M250V|Y265W
2
2
0
0
250
M
V
9
CONSERVATION
2ZTA
320
null
250|265
A|B
H
true
false
108.153446
31.168334
15,730
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
2ZTA_A:M2V 2ZTA_A:Y17W
18
-4
null
null
15.77
0.17
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DTM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":57724,"numValue":18.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57725,"numValue":-4.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57726,"numValue":15.77,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":57727,"numValue":0.17,"references":[...
[{"id":8360,"numValue":9.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8375,"numValue":5.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7941
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,941
train
mutant
7,357
128
8,027
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
M250V|Y265W
M250V|Y265W
2
2
0
0
250
M
V
9
CONSERVATION
2ZTA
320
null
250|265
A|B
H
true
false
108.153446
31.168334
15,732
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
2ZTA_A:M2V 2ZTA_A:Y17W
17.9
-4.1
null
null
15.54
0.14
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DTM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":57736,"numValue":17.9,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57737,"numValue":-4.1,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57738,"numValue":15.54,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":57739,"numValue":0.14,"references":[...
[{"id":8360,"numValue":9.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8375,"numValue":5.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7943
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,943
train
mutant
7,357
128
8,027
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
M250V|Y265W
M250V|Y265W
2
2
0
0
250
M
V
9
CONSERVATION
2ZTA
320
null
250|265
A|B
H
true
false
108.153446
31.168334
15,734
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
2ZTA_A:M2V 2ZTA_A:Y17W
56.7
7.7
null
null
24.62
0.24
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DTM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":57748,"numValue":56.7,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57749,"numValue":7.7,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57750,"numValue":24.62,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":57751,"numValue":0.24,"references":[]...
[{"id":8360,"numValue":9.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8375,"numValue":5.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7944
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,944
train
mutant
7,357
128
8,027
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
M250V|Y265W
M250V|Y265W
2
2
0
0
250
M
V
9
CONSERVATION
2ZTA
320
null
250|265
A|B
H
true
false
108.153446
31.168334
15,735
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
2ZTA_A:M2V 2ZTA_A:Y17W
55.7
7.4
null
null
22.23
0.24
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DTM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":57754,"numValue":55.7,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57755,"numValue":7.4,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57756,"numValue":22.23,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":57757,"numValue":0.24,"references":[]...
[{"id":8360,"numValue":9.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8375,"numValue":5.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7945
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,945
train
mutant
7,357
128
8,027
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
M250V|Y265W
M250V|Y265W
2
2
0
0
250
M
V
9
CONSERVATION
2ZTA
320
null
250|265
A|B
H
true
false
108.153446
31.168334
15,738
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
2ZTA_A:M2V 2ZTA_A:Y17W
66.2
-1.5
null
null
54.97
0.55
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DTM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":57772,"numValue":66.2,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57773,"numValue":-1.5,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57774,"numValue":54.97,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":57775,"numValue":0.55,"references":[...
[{"id":8360,"numValue":9.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8375,"numValue":5.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7946
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,946
train
mutant
7,357
128
8,027
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
M250V|Y265W
M250V|Y265W
2
2
0
0
250
M
V
9
CONSERVATION
2ZTA
320
null
250|265
A|B
H
true
false
108.153446
31.168334
15,739
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
2ZTA_A:M2V 2ZTA_A:Y17W
69.3
-2.3
null
null
55.45
0.55
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DTM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":57778,"numValue":69.3,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57779,"numValue":-2.3,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57780,"numValue":55.45,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":57781,"numValue":0.55,"references":[...
[{"id":8360,"numValue":9.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8375,"numValue":5.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7947
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,947
train
mutant
7,357
128
8,027
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
M250V|Y265W
M250V|Y265W
2
2
0
0
250
M
V
9
CONSERVATION
2ZTA
320
null
250|265
A|B
H
true
false
108.153446
31.168334
15,740
ProTherm
7.4
DSC
Thermal
sodium phosphate
30 mM
null
NaCl
100 mM
2ZTA_A:M2V 2ZTA_A:Y17W
71.7
-3.5
null
null
54.73
0.5
null
null
null
null
null
null
null
null
null
null
yes
4.0
TM|DTM|DH|DCP|STATE|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
943
ARTICLE
Unfolding of a leucine zipper is not a simple two-state transition.
2,002
10.1016/s0022-2836(02)00699-x
12206769
J Mol Biol;321;891-908
2
Dragan Anatoly I|Privalov Peter L
[{"numValue":7.4,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"IO...
[{"datasets":[],"id":57784,"numValue":71.7,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57785,"numValue":-3.5,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57786,"numValue":54.73,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":57787,"numValue":0.5,"references":[]...
[{"id":8360,"numValue":9.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8375,"numValue":5.0,"position":265,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7948
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,948
train
mutant
6,390
128
7,024
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
K256A
K256A
1
1
0
0
256
K
A
8
CONSERVATION
2ZTA
320
null
256
A|B
H
true
true
88.420308
23.607222
13,767
ProTherm
7
CD
Urea
Sodium phosphate
50mM
15
NaCl
150 mM
2ZTA_A:K8A
null
null
9.71
0.39
null
null
null
null
0.91
null
null
null
null
null
null
null
Unknown
DG|DDG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
867
ARTICLE
Salt-bridges can stabilize but do not accelerate the folding of the homodimeric coiled-coil peptide GCN4-p1.
2,004
10.1016/j.jmb.2003.12.069
15037063
J Mol Biol;336;989-96
3
Matthews C Robert|Ibarra-Molero Beatriz|Zitzewitz Jill A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":15.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50mM","type":"BUFFE...
[{"datasets":[],"id":50817,"numValue":9.71,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":50818,"numValue":0.39,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":50819,"numValue":0.91,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":50820,"numValue":null,"references":[],...
[{"id":8366,"numValue":8.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7949
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,949
train
mutant
8,156
128
8,886
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
K256A|E259Q
K256A|E259Q
2
2
0
0
256
K
A
8
CONSERVATION
2ZTA
320
null
256|259
A|B
H
true
true
93.015785
24.650833
17,362
ProTherm
7
CD
Urea
Sodium phosphate
50mM
15
NaCl
150 mM
2ZTA_A:K8A 2ZTA_A:E11Q
null
null
9.53
0.57
null
null
null
null
0.94
null
null
null
null
null
null
null
Unknown
DG|DDG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
867
ARTICLE
Salt-bridges can stabilize but do not accelerate the folding of the homodimeric coiled-coil peptide GCN4-p1.
2,004
10.1016/j.jmb.2003.12.069
15037063
J Mol Biol;336;989-96
3
Matthews C Robert|Ibarra-Molero Beatriz|Zitzewitz Jill A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":15.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50mM","type":"BUFFE...
[{"datasets":[],"id":64116,"numValue":9.53,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":64117,"numValue":0.57,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":64118,"numValue":0.94,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":64119,"numValue":null,"references":[],...
[{"id":8366,"numValue":8.0,"position":256,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8369,"numValue":4.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7950
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,950
train
mutant
6,965
128
7,616
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
V257I|N264I|V271N|V278I
V257I|N264I|V271N|V278I
4
4
0
0
257
V
I
9
CONSERVATION
2ZTA
320
null
257|264|271|278
A|B
H
true
true
25.580718
29.69442
14,827
ProTherm
7
CD
Thermal
Potassium phosphate
10 mM
null
2ZTA_A:V9I 2ZTA_A:N16I 2ZTA_A:V23N 2ZTA_A:V30I
79.5
null
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes(>95%)
TM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
919
ARTICLE
The contribution of buried polar groups to the conformational stability of the GCN4 coiled coil.
2,000
10.1006/jmbi.2000.3936
10903875
J Mol Biol;300;1377-87
4
Zhu H|Scholtz J M|Celinski S A|Hu J C
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"2ZTA_A:V9I 2ZT...
[{"datasets":[],"id":54739,"numValue":79.5,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54740,"numValue":null,"references":[],"strValue":"yes(>95%)","type":"REVERSIBILITY"}]
[{"id":8367,"numValue":9.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8374,"numValue":9.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8381,"numValue":9.0,"position":271,"positionArray":null,"positionRang...
fireprotdb:7951
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,951
train
mutant
6,965
128
7,616
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
V257I|N264I|V271N|V278I
V257I|N264I|V271N|V278I
4
4
0
0
257
V
I
9
CONSERVATION
2ZTA
320
null
257|264|271|278
A|B
H
true
true
25.580718
29.69442
14,957
ProTherm
7
CD
Thermal
Potassium phosphate
10 mM
60
2ZTA_A:V9I 2ZTA_A:N16I 2ZTA_A:V23N 2ZTA_A:V30I
null
null
9.9
null
null
null
null
null
null
null
null
null
null
null
null
null
yes(>95%)
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
919
ARTICLE
The contribution of buried polar groups to the conformational stability of the GCN4 coiled coil.
2,000
10.1006/jmbi.2000.3936
10903875
J Mol Biol;300;1377-87
4
Zhu H|Scholtz J M|Celinski S A|Hu J C
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":60.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type"...
[{"datasets":[],"id":55074,"numValue":9.9,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":55075,"numValue":null,"references":[],"strValue":"yes(>95%)","type":"REVERSIBILITY"}]
[{"id":8367,"numValue":9.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8374,"numValue":9.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8381,"numValue":9.0,"position":271,"positionArray":null,"positionRang...
fireprotdb:7952
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,952
train
mutant
6,966
128
7,617
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
V257I|V271I|V278I
V257I|V271I|V278I
3
3
0
0
257
V
I
9
CONSERVATION
2ZTA
320
null
257|271|278
A|B
H
true
true
32.853528
32.78381
14,828
ProTherm
7
CD
Thermal
Potassium phosphate
10 mM
null
2ZTA_A:V9I 2ZTA_A:V23I 2ZTA_A:V30I
69.5
null
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes(>95%)
TM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
919
ARTICLE
The contribution of buried polar groups to the conformational stability of the GCN4 coiled coil.
2,000
10.1006/jmbi.2000.3936
10903875
J Mol Biol;300;1377-87
4
Zhu H|Scholtz J M|Celinski S A|Hu J C
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"2ZTA_A:V9I 2ZT...
[{"datasets":[],"id":54741,"numValue":69.5,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54742,"numValue":null,"references":[],"strValue":"yes(>95%)","type":"REVERSIBILITY"}]
[{"id":8367,"numValue":9.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8381,"numValue":9.0,"position":271,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8388,"numValue":9.0,"position":278,"positionArray":null,"positionRang...
fireprotdb:7954
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,954
train
mutant
6,967
128
7,618
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
V257I|N264I|V271N|V278N
V257I|N264I|V271N|V278N
4
4
0
0
257
V
I
9
CONSERVATION
2ZTA
320
null
257|264|271|278
A|B
H
true
true
25.580718
29.69442
14,829
ProTherm
7
CD
Thermal
Potassium phosphate
10 mM
null
2ZTA_A:V9I 2ZTA_A:N16I 2ZTA_A:V23N 2ZTA_A:V30N
64
null
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes(>95%)
TM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
919
ARTICLE
The contribution of buried polar groups to the conformational stability of the GCN4 coiled coil.
2,000
10.1006/jmbi.2000.3936
10903875
J Mol Biol;300;1377-87
4
Zhu H|Scholtz J M|Celinski S A|Hu J C
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"2ZTA_A:V9I 2ZT...
[{"datasets":[],"id":54743,"numValue":64.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54744,"numValue":null,"references":[],"strValue":"yes(>95%)","type":"REVERSIBILITY"}]
[{"id":8367,"numValue":9.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8374,"numValue":9.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8381,"numValue":9.0,"position":271,"positionArray":null,"positionRang...
fireprotdb:7955
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,955
train
mutant
6,967
128
7,618
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
V257I|N264I|V271N|V278N
V257I|N264I|V271N|V278N
4
4
0
0
257
V
I
9
CONSERVATION
2ZTA
320
null
257|264|271|278
A|B
H
true
true
25.580718
29.69442
14,959
ProTherm
7
CD
Thermal
Potassium phosphate
10 mM
60
2ZTA_A:V9I 2ZTA_A:N16I 2ZTA_A:V23N 2ZTA_A:V30N
null
null
7.3
null
null
null
null
null
null
null
null
null
null
null
null
null
yes(>95%)
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
919
ARTICLE
The contribution of buried polar groups to the conformational stability of the GCN4 coiled coil.
2,000
10.1006/jmbi.2000.3936
10903875
J Mol Biol;300;1377-87
4
Zhu H|Scholtz J M|Celinski S A|Hu J C
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":60.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type"...
[{"datasets":[],"id":55078,"numValue":7.3,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":55079,"numValue":null,"references":[],"strValue":"yes(>95%)","type":"REVERSIBILITY"}]
[{"id":8367,"numValue":9.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8374,"numValue":9.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8381,"numValue":9.0,"position":271,"positionArray":null,"positionRang...
fireprotdb:7956
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,956
train
mutant
6,968
128
7,619
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
V257I|V271N|V278I
V257I|V271N|V278I
3
3
0
0
257
V
I
9
CONSERVATION
2ZTA
320
null
257|271|278
A|B
H
true
true
32.853528
32.78381
14,830
ProTherm
7
CD
Thermal
Potassium phosphate
10 mM
null
2ZTA_A:V9I 2ZTA_A:V23N 2ZTA_A:V30I
52.5
null
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes(>95%)
TM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
919
ARTICLE
The contribution of buried polar groups to the conformational stability of the GCN4 coiled coil.
2,000
10.1006/jmbi.2000.3936
10903875
J Mol Biol;300;1377-87
4
Zhu H|Scholtz J M|Celinski S A|Hu J C
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"2ZTA_A:V9I 2ZT...
[{"datasets":[],"id":54745,"numValue":52.5,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54746,"numValue":null,"references":[],"strValue":"yes(>95%)","type":"REVERSIBILITY"}]
[{"id":8367,"numValue":9.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8381,"numValue":9.0,"position":271,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8388,"numValue":9.0,"position":278,"positionArray":null,"positionRang...
fireprotdb:7957
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,957
train
mutant
6,968
128
7,619
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
V257I|V271N|V278I
V257I|V271N|V278I
3
3
0
0
257
V
I
9
CONSERVATION
2ZTA
320
null
257|271|278
A|B
H
true
true
32.853528
32.78381
14,960
ProTherm
7
CD
Thermal
Potassium phosphate
10 mM
60
2ZTA_A:V9I 2ZTA_A:V23N 2ZTA_A:V30I
null
null
5.5
null
null
null
null
null
null
null
null
null
null
null
null
null
yes(>95%)
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
919
ARTICLE
The contribution of buried polar groups to the conformational stability of the GCN4 coiled coil.
2,000
10.1006/jmbi.2000.3936
10903875
J Mol Biol;300;1377-87
4
Zhu H|Scholtz J M|Celinski S A|Hu J C
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":60.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type"...
[{"datasets":[],"id":55080,"numValue":5.5,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":55081,"numValue":null,"references":[],"strValue":"yes(>95%)","type":"REVERSIBILITY"}]
[{"id":8367,"numValue":9.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8381,"numValue":9.0,"position":271,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8388,"numValue":9.0,"position":278,"positionArray":null,"positionRang...
fireprotdb:7958
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,958
train
mutant
6,969
128
7,620
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
V257I|V271I|V278N
V257I|V271I|V278N
3
3
0
0
257
V
I
9
CONSERVATION
2ZTA
320
null
257|271|278
A|B
H
true
true
32.853528
32.78381
14,831
ProTherm
7
CD
Thermal
Potassium phosphate
10 mM
null
2ZTA_A:V9I 2ZTA_A:V23I 2ZTA_A:V30N
50.6
null
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes(>95%)
TM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
919
ARTICLE
The contribution of buried polar groups to the conformational stability of the GCN4 coiled coil.
2,000
10.1006/jmbi.2000.3936
10903875
J Mol Biol;300;1377-87
4
Zhu H|Scholtz J M|Celinski S A|Hu J C
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"2ZTA_A:V9I 2ZT...
[{"datasets":[],"id":54747,"numValue":50.6,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54748,"numValue":null,"references":[],"strValue":"yes(>95%)","type":"REVERSIBILITY"}]
[{"id":8367,"numValue":9.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8381,"numValue":9.0,"position":271,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8388,"numValue":9.0,"position":278,"positionArray":null,"positionRang...
fireprotdb:7959
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,959
train
mutant
6,969
128
7,620
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
V257I|V271I|V278N
V257I|V271I|V278N
3
3
0
0
257
V
I
9
CONSERVATION
2ZTA
320
null
257|271|278
A|B
H
true
true
32.853528
32.78381
14,961
ProTherm
7
CD
Thermal
Potassium phosphate
10 mM
60
2ZTA_A:V9I 2ZTA_A:V23I 2ZTA_A:V30N
null
null
5.3
null
null
null
null
null
null
null
null
null
null
null
null
null
yes(>95%)
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
919
ARTICLE
The contribution of buried polar groups to the conformational stability of the GCN4 coiled coil.
2,000
10.1006/jmbi.2000.3936
10903875
J Mol Biol;300;1377-87
4
Zhu H|Scholtz J M|Celinski S A|Hu J C
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":60.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type"...
[{"datasets":[],"id":55082,"numValue":5.3,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":55083,"numValue":null,"references":[],"strValue":"yes(>95%)","type":"REVERSIBILITY"}]
[{"id":8367,"numValue":9.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8381,"numValue":9.0,"position":271,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8388,"numValue":9.0,"position":278,"positionArray":null,"positionRang...
fireprotdb:7960
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,960
train
mutant
6,970
128
7,621
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
V257N|N264I|V271N|V278I
V257N|N264I|V271N|V278I
4
4
0
0
257
V
N
9
CONSERVATION
2ZTA
320
null
257|264|271|278
A|B
H
true
true
25.580718
29.69442
14,832
ProTherm
7
CD
Thermal
Potassium phosphate
10 mM
null
2ZTA_A:V9N 2ZTA_A:N16I 2ZTA_A:V23N 2ZTA_A:V30I
45
null
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes(>95%)
TM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
919
ARTICLE
The contribution of buried polar groups to the conformational stability of the GCN4 coiled coil.
2,000
10.1006/jmbi.2000.3936
10903875
J Mol Biol;300;1377-87
4
Zhu H|Scholtz J M|Celinski S A|Hu J C
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"2ZTA_A:V9N 2ZT...
[{"datasets":[],"id":54749,"numValue":45.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54750,"numValue":null,"references":[],"strValue":"yes(>95%)","type":"REVERSIBILITY"}]
[{"id":8367,"numValue":9.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8374,"numValue":9.0,"position":264,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8381,"numValue":9.0,"position":271,"positionArray":null,"positionRang...
fireprotdb:7962
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,962
train
mutant
6,971
128
7,622
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
V257N|V271N|V278I
V257N|V271N|V278I
3
3
0
0
257
V
N
9
CONSERVATION
2ZTA
320
null
257|271|278
A|B
H
true
true
32.853528
32.78381
14,833
ProTherm
7
CD
Thermal
Potassium phosphate
10 mM
null
2ZTA_A:V9N 2ZTA_A:V23N 2ZTA_A:V30I
21.2
null
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes(>95%)
TM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
919
ARTICLE
The contribution of buried polar groups to the conformational stability of the GCN4 coiled coil.
2,000
10.1006/jmbi.2000.3936
10903875
J Mol Biol;300;1377-87
4
Zhu H|Scholtz J M|Celinski S A|Hu J C
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"2ZTA_A:V9N 2ZT...
[{"datasets":[],"id":54751,"numValue":21.2,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54752,"numValue":null,"references":[],"strValue":"yes(>95%)","type":"REVERSIBILITY"}]
[{"id":8367,"numValue":9.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8381,"numValue":9.0,"position":271,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8388,"numValue":9.0,"position":278,"positionArray":null,"positionRang...
fireprotdb:7963
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,963
train
mutant
6,971
128
7,622
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
V257N|V271N|V278I
V257N|V271N|V278I
3
3
0
0
257
V
N
9
CONSERVATION
2ZTA
320
null
257|271|278
A|B
H
true
true
32.853528
32.78381
14,963
ProTherm
7
CD
Thermal
Potassium phosphate
10 mM
60
2ZTA_A:V9N 2ZTA_A:V23N 2ZTA_A:V30I
null
null
0.6
null
null
null
null
null
null
null
null
null
null
null
null
null
yes(>95%)
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
919
ARTICLE
The contribution of buried polar groups to the conformational stability of the GCN4 coiled coil.
2,000
10.1006/jmbi.2000.3936
10903875
J Mol Biol;300;1377-87
4
Zhu H|Scholtz J M|Celinski S A|Hu J C
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":60.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type"...
[{"datasets":[],"id":55086,"numValue":0.6,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":55087,"numValue":null,"references":[],"strValue":"yes(>95%)","type":"REVERSIBILITY"}]
[{"id":8367,"numValue":9.0,"position":257,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8381,"numValue":9.0,"position":271,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8388,"numValue":9.0,"position":278,"positionArray":null,"positionRang...
fireprotdb:7964
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,964
train
mutant
114
128
129
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
E259A
E259A
1
1
0
0
259
E
A
4
CONSERVATION
2ZTA
320
null
259
A|B
H
true
false
97.611261
25.694445
226
ProTherm
7
CD
Thermal
sodium phosphate
10 mM
null
2ZTA_A:E11A
51
null
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes
TM|REVERSIBILITY
AUTOMUTE_S1925.csv|EASE-MM_S1676.csv|I_Mutant2.0_S1948.csv|I_Mutant2.0_S2087.csv|iPTREE-STAB_S1859.csv|M47andM8_S2760.csv|Saraboji_S1396.csv|STRUM_Q3421.csv|SVM-WIN31_SVM-3D12_S1634.csv|SVM-WIN31_SVM-3D12_S1681.csv
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
18
ARTICLE
An intrahelical salt bridge within the trigger site stabilizes the GCN4 leucine zipper.
2,001
10.1074/jbc.M010492200
11134036
J Biol Chem;276;13685-8
6
Frank S|Schulthess T|Landwehr R|Lustig A|Kammerer R A|Jaravine V A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"2ZTA_A:E11A","typ...
[{"datasets":["AUTOMUTE_S1925.csv","EASE-MM_S1676.csv","I_Mutant2.0_S1948.csv","I_Mutant2.0_S2087.csv","iPTREE-STAB_S1859.csv","M47andM8_S2760.csv","Saraboji_S1396.csv","STRUM_Q3421.csv","SVM-WIN31_SVM-3D12_S1634.csv","SVM-WIN31_SVM-3D12_S1681.csv"],"id":943,"numValue":51.0,"references":[],"strValue":null,"type":"TM"},...
[{"id":8369,"numValue":4.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7965
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,965
train
mutant
6,391
128
7,025
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
E259Q
E259Q
1
1
0
0
259
E
Q
4
CONSERVATION
2ZTA
320
null
259
A|B
H
true
false
97.611261
25.694445
13,768
ProTherm
7
CD
Urea
Sodium phosphate
50mM
15
NaCl
150 mM
2ZTA_A:E11Q
null
null
9.36
0.74
null
null
null
null
1.02
null
null
null
null
null
null
null
Unknown
DG|DDG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
867
ARTICLE
Salt-bridges can stabilize but do not accelerate the folding of the homodimeric coiled-coil peptide GCN4-p1.
2,004
10.1016/j.jmb.2003.12.069
15037063
J Mol Biol;336;989-96
3
Matthews C Robert|Ibarra-Molero Beatriz|Zitzewitz Jill A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":15.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50mM","type":"BUFFE...
[{"datasets":[],"id":50821,"numValue":9.36,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":50822,"numValue":0.74,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":50823,"numValue":1.02,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":50824,"numValue":null,"references":[],...
[{"id":8369,"numValue":4.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7966
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,966
train
mutant
7,292
128
7,962
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
E259A|R273A
E259A|R273A
2
2
0
0
259
E
A
4
CONSERVATION
2ZTA
320
null
259|273
A|B
H
true
false
113.649764
37.545177
15,649
ProTherm
7
CD
Thermal
sodium phosphate
10 mM
null
2ZTA_A:E11A 2ZTA_A:R25A
35
null
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes
TM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
18
ARTICLE
An intrahelical salt bridge within the trigger site stabilizes the GCN4 leucine zipper.
2,001
10.1074/jbc.M010492200
11134036
J Biol Chem;276;13685-8
6
Frank S|Schulthess T|Landwehr R|Lustig A|Kammerer R A|Jaravine V A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"2ZTA_A:E11A 2ZTA_...
[{"datasets":[],"id":57434,"numValue":35.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57435,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8369,"numValue":4.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8383,"numValue":7.0,"position":273,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7967
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,967
train
mutant
8,157
128
8,887
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
E259Q|K263A
E259Q|K263A
2
2
0
0
259
E
Q
4
CONSERVATION
2ZTA
320
null
259|263
A|B
H
true
false
94.99286
26.5675
17,363
ProTherm
7
CD
Urea
Sodium phosphate
50mM
15
NaCl
150 mM
2ZTA_A:E11Q 2ZTA_A:K15A
null
null
9.96
0.14
null
null
null
null
0.97
null
null
null
null
null
null
null
Unknown
DG|DDG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
867
ARTICLE
Salt-bridges can stabilize but do not accelerate the folding of the homodimeric coiled-coil peptide GCN4-p1.
2,004
10.1016/j.jmb.2003.12.069
15037063
J Mol Biol;336;989-96
3
Matthews C Robert|Ibarra-Molero Beatriz|Zitzewitz Jill A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":15.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50mM","type":"BUFFE...
[{"datasets":[],"id":64120,"numValue":9.96,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":64121,"numValue":0.14,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":64122,"numValue":0.97,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":64123,"numValue":null,"references":[],...
[{"id":8369,"numValue":4.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8373,"numValue":5.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7968
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,968
train
mutant
8,161
128
8,891
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
E259Q|E268Q|E270Q
E259Q|E268Q|E270Q
3
3
0
0
259
E
Q
4
CONSERVATION
2ZTA
320
null
259|268|270
A|B
H
true
false
66.535739
31.147778
17,367
ProTherm
7
CD
Urea
Sodium phosphate
50mM
15
NaCl
150 mM
2ZTA_A:E11Q 2ZTA_A:E20Q 2ZTA_A:E22Q
null
null
7.73
2.37
null
null
null
null
1.15
null
null
null
null
null
null
null
Unknown
DG|DDG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
867
ARTICLE
Salt-bridges can stabilize but do not accelerate the folding of the homodimeric coiled-coil peptide GCN4-p1.
2,004
10.1016/j.jmb.2003.12.069
15037063
J Mol Biol;336;989-96
3
Matthews C Robert|Ibarra-Molero Beatriz|Zitzewitz Jill A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":15.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50mM","type":"BUFFE...
[{"datasets":[],"id":64136,"numValue":7.73,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":64137,"numValue":2.37,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":64138,"numValue":1.15,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":64139,"numValue":null,"references":[],...
[{"id":8369,"numValue":4.0,"position":259,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8378,"numValue":8.0,"position":268,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8380,"numValue":9.0,"position":270,"positionArray":null,"positionRang...
fireprotdb:7969
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,969
train
mutant
6,871
128
7,513
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262R|H266E|N269R
S262R|H266E|N269R
3
3
0
0
262
S
R
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
14,701
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
null
NaCl
150 mM
2ZTA_A:S14R 2ZTA_A:H18E 2ZTA_A:N21R
67
22
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION...
[{"datasets":[],"id":54368,"numValue":67.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54369,"numValue":22.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":54370,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7970
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,970
train
mutant
6,871
128
7,513
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262R|H266E|N269R
S262R|H266E|N269R
3
3
0
0
262
S
R
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
15,085
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
45
NaCl
150 mM
2ZTA_A:S14R 2ZTA_A:H18E 2ZTA_A:N21R
null
null
null
-1.72
null
1.35
null
null
null
null
null
null
null
null
null
null
yes
DCP|DDG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":45.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"B...
[{"datasets":[],"id":55373,"numValue":1.35,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":55374,"numValue":-1.72,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":55375,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7971
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,971
train
mutant
6,872
128
7,514
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262R|H266E|N269A
S262R|H266E|N269A
3
3
0
0
262
S
R
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
14,702
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
null
NaCl
150 mM
2ZTA_A:S14R 2ZTA_A:H18E 2ZTA_A:N21A
67
21
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION...
[{"datasets":[],"id":54371,"numValue":67.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54372,"numValue":21.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":54373,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7972
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,972
train
mutant
6,872
128
7,514
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262R|H266E|N269A
S262R|H266E|N269A
3
3
0
0
262
S
R
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
15,086
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
45
NaCl
150 mM
2ZTA_A:S14R 2ZTA_A:H18E 2ZTA_A:N21A
null
null
null
-1.64
null
1.35
null
null
null
null
null
null
null
null
null
null
yes
DCP|DDG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":45.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"B...
[{"datasets":[],"id":55376,"numValue":1.35,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":55377,"numValue":-1.64,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":55378,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7973
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,973
train
mutant
6,873
128
7,515
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262A|H266A|N269R
S262A|H266A|N269R
3
3
0
0
262
S
A
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
14,703
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
null
NaCl
150 mM
2ZTA_A:S14A 2ZTA_A:H18A 2ZTA_A:N21R
67
16
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION...
[{"datasets":[],"id":54374,"numValue":67.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54375,"numValue":16.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":54376,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7974
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,974
train
mutant
6,873
128
7,515
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262A|H266A|N269R
S262A|H266A|N269R
3
3
0
0
262
S
A
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
15,087
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
45
NaCl
150 mM
2ZTA_A:S14A 2ZTA_A:H18A 2ZTA_A:N21R
null
null
null
-1.23
null
1.35
null
null
null
null
null
null
null
null
null
null
yes
DCP|DDG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":45.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"B...
[{"datasets":[],"id":55379,"numValue":1.35,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":55380,"numValue":-1.23,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":55381,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7975
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,975
train
mutant
6,874
128
7,516
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262R|H266A|N269R
S262R|H266A|N269R
3
3
0
0
262
S
R
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
14,704
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
null
NaCl
150 mM
2ZTA_A:S14R 2ZTA_A:H18A 2ZTA_A:N21R
67
15
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION...
[{"datasets":[],"id":54377,"numValue":67.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54378,"numValue":15.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":54379,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7976
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,976
train
mutant
6,874
128
7,516
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262R|H266A|N269R
S262R|H266A|N269R
3
3
0
0
262
S
R
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
15,088
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
45
NaCl
150 mM
2ZTA_A:S14R 2ZTA_A:H18A 2ZTA_A:N21R
null
null
null
-1.15
null
1.35
null
null
null
null
null
null
null
null
null
null
yes
DCP|DDG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":45.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"B...
[{"datasets":[],"id":55382,"numValue":1.35,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":55383,"numValue":-1.15,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":55384,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7977
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,977
train
mutant
6,875
128
7,517
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262A|H266E|N269R
S262A|H266E|N269R
3
3
0
0
262
S
A
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
14,705
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
null
NaCl
150 mM
2ZTA_A:S14A 2ZTA_A:H18E 2ZTA_A:N21R
67
15
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION...
[{"datasets":[],"id":54380,"numValue":67.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54381,"numValue":15.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":54382,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7978
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,978
train
mutant
6,875
128
7,517
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262A|H266E|N269R
S262A|H266E|N269R
3
3
0
0
262
S
A
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
15,089
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
45
NaCl
150 mM
2ZTA_A:S14A 2ZTA_A:H18E 2ZTA_A:N21R
null
null
null
-1.15
null
1.35
null
null
null
null
null
null
null
null
null
null
yes
DCP|DDG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":45.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"B...
[{"datasets":[],"id":55385,"numValue":1.35,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":55386,"numValue":-1.15,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":55387,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7979
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,979
train
mutant
6,876
128
7,518
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262R|H266A|N269A
S262R|H266A|N269A
3
3
0
0
262
S
R
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
14,706
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
null
NaCl
150 mM
2ZTA_A:S14R 2ZTA_A:H18A 2ZTA_A:N21A
67
14
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION...
[{"datasets":[],"id":54383,"numValue":67.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54384,"numValue":14.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":54385,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7980
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,980
train
mutant
6,876
128
7,518
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262R|H266A|N269A
S262R|H266A|N269A
3
3
0
0
262
S
R
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
15,090
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
45
NaCl
150 mM
2ZTA_A:S14R 2ZTA_A:H18A 2ZTA_A:N21A
null
null
null
-1.07
null
1.35
null
null
null
null
null
null
null
null
null
null
yes
DCP|DDG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":45.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"B...
[{"datasets":[],"id":55388,"numValue":1.35,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":55389,"numValue":-1.07,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":55390,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7981
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,981
train
mutant
6,877
128
7,519
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262A|H266A|N269A
S262A|H266A|N269A
3
3
0
0
262
S
A
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
14,707
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
null
NaCl
150 mM
2ZTA_A:S14A 2ZTA_A:H18A 2ZTA_A:N21A
67
14
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION...
[{"datasets":[],"id":54386,"numValue":67.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54387,"numValue":14.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":54388,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7982
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,982
train
mutant
6,877
128
7,519
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262A|H266A|N269A
S262A|H266A|N269A
3
3
0
0
262
S
A
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
15,091
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
45
NaCl
150 mM
2ZTA_A:S14A 2ZTA_A:H18A 2ZTA_A:N21A
null
null
null
-1.07
null
1.35
null
null
null
null
null
null
null
null
null
null
yes
DCP|DDG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":45.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"B...
[{"datasets":[],"id":55391,"numValue":1.35,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":55392,"numValue":-1.07,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":55393,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7983
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,983
train
mutant
6,878
128
7,520
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262A|H266E|N269A
S262A|H266E|N269A
3
3
0
0
262
S
A
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
14,708
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
null
NaCl
150 mM
2ZTA_A:S14A 2ZTA_A:H18E 2ZTA_A:N21A
67
10
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION...
[{"datasets":[],"id":54389,"numValue":67.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54390,"numValue":10.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":54391,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7984
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,984
train
mutant
6,878
128
7,520
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
S262A|H266E|N269A
S262A|H266E|N269A
3
3
0
0
262
S
A
4
CONSERVATION
2ZTA
320
null
262|266|269
A|B
H
false
false
90.002229
27.496305
15,092
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
45
NaCl
150 mM
2ZTA_A:S14A 2ZTA_A:H18E 2ZTA_A:N21A
null
null
null
-0.76
null
1.35
null
null
null
null
null
null
null
null
null
null
yes
DCP|DDG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":45.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"B...
[{"datasets":[],"id":55394,"numValue":1.35,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":55395,"numValue":-0.76,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":55396,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8372,"numValue":4.0,"position":262,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRang...
fireprotdb:7985
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,985
train
mutant
6,392
128
7,026
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
K263A
K263A
1
1
0
0
263
K
A
5
CONSERVATION
2ZTA
320
null
263
A|B
H
false
false
92.37446
27.440556
13,769
ProTherm
7
CD
Urea
Sodium phosphate
50mM
15
NaCl
150 mM
2ZTA_A:K15A
null
null
9.69
0.41
null
null
null
null
0.88
null
null
null
null
null
null
null
Unknown
DG|DDG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
867
ARTICLE
Salt-bridges can stabilize but do not accelerate the folding of the homodimeric coiled-coil peptide GCN4-p1.
2,004
10.1016/j.jmb.2003.12.069
15037063
J Mol Biol;336;989-96
3
Matthews C Robert|Ibarra-Molero Beatriz|Zitzewitz Jill A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":15.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50mM","type":"BUFFE...
[{"datasets":[],"id":50825,"numValue":9.69,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":50826,"numValue":0.41,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":50827,"numValue":0.88,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":50828,"numValue":null,"references":[],...
[{"id":8373,"numValue":5.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7986
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,986
train
mutant
8,158
128
8,888
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
K263A|E268Q
K263A|E268Q
2
2
0
0
263
K
A
5
CONSERVATION
2ZTA
320
null
263|268
A|B
H
false
false
82.042057
29.044167
17,364
ProTherm
7
CD
Urea
Sodium phosphate
50mM
15
NaCl
150 mM
2ZTA_A:K15A 2ZTA_A:E20Q
null
null
10.92
-0.82
null
null
null
null
0.96
null
null
null
null
null
null
null
Unknown
DG|DDG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
867
ARTICLE
Salt-bridges can stabilize but do not accelerate the folding of the homodimeric coiled-coil peptide GCN4-p1.
2,004
10.1016/j.jmb.2003.12.069
15037063
J Mol Biol;336;989-96
3
Matthews C Robert|Ibarra-Molero Beatriz|Zitzewitz Jill A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":15.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50mM","type":"BUFFE...
[{"datasets":[],"id":64124,"numValue":10.92,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":64125,"numValue":-0.82,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":64126,"numValue":0.96,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":64127,"numValue":null,"references":[...
[{"id":8373,"numValue":5.0,"position":263,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8378,"numValue":8.0,"position":268,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7988
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,988
train
mutant
6,879
128
7,521
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
H266R|N269E
H266R|N269E
2
2
0
0
266
H
R
4
CONSERVATION
2ZTA
320
null
266|269
A|B
H
false
false
100.000302
30.244875
15,093
ProTherm
7
CD
Thermal
Sodium phosphate
50 mM
45
NaCl
150 mM
2ZTA_A:H18R 2ZTA_A:N21E
null
null
null
-0.22
null
1.35
null
null
null
null
null
null
null
null
null
null
yes
DCP|DDG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
908
ARTICLE
Surface salt bridges stabilize the GCN4 leucine zipper.
1,998
10.1002/pro.5560071121
9828010
Protein Sci;7;2431-7
4
Lu M|Kallenbach N R|Spek E J|Bui A H
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":45.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"B...
[{"datasets":[],"id":55397,"numValue":1.35,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":55398,"numValue":-0.22,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":55399,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8376,"numValue":4.0,"position":266,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8379,"numValue":5.0,"position":269,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7990
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,990
train
mutant
8,160
128
8,890
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
E268Q|E270Q
E268Q|E270Q
2
2
0
0
268
E
Q
8
CONSERVATION
2ZTA
320
null
268|270
A|B
H
false
false
50.997979
33.874444
17,366
ProTherm
7
CD
Urea
Sodium phosphate
50mM
15
NaCl
150 mM
2ZTA_A:E20Q 2ZTA_A:E22Q
null
null
8.38
1.72
null
null
null
null
1.06
null
null
null
null
null
null
null
Unknown
DG|DDG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
867
ARTICLE
Salt-bridges can stabilize but do not accelerate the folding of the homodimeric coiled-coil peptide GCN4-p1.
2,004
10.1016/j.jmb.2003.12.069
15037063
J Mol Biol;336;989-96
3
Matthews C Robert|Ibarra-Molero Beatriz|Zitzewitz Jill A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":15.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50mM","type":"BUFFE...
[{"datasets":[],"id":64132,"numValue":8.38,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":64133,"numValue":1.72,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":64134,"numValue":1.06,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":64135,"numValue":null,"references":[],...
[{"id":8378,"numValue":8.0,"position":268,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8380,"numValue":9.0,"position":270,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7992
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,992
train
mutant
8,159
128
8,889
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
E270Q|K275A
E270Q|K275A
2
2
0
0
270
E
Q
9
CONSERVATION
2ZTA
320
null
270|275
A|B
H
false
false
66.067543
43.550556
17,365
ProTherm
7
CD
Urea
Sodium phosphate
50mM
15
NaCl
150 mM
2ZTA_A:E22Q 2ZTA_A:K27A
null
null
7.3
2.8
null
null
null
null
0.98
null
null
null
null
null
null
null
Unknown
DG|DDG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
867
ARTICLE
Salt-bridges can stabilize but do not accelerate the folding of the homodimeric coiled-coil peptide GCN4-p1.
2,004
10.1016/j.jmb.2003.12.069
15037063
J Mol Biol;336;989-96
3
Matthews C Robert|Ibarra-Molero Beatriz|Zitzewitz Jill A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":15.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50mM","type":"BUFFE...
[{"datasets":[],"id":64128,"numValue":7.3,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":64129,"numValue":2.8,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":64130,"numValue":0.98,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":64131,"numValue":null,"references":[],"s...
[{"id":8380,"numValue":9.0,"position":270,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8385,"numValue":6.0,"position":275,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7993
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,993
train
mutant
115
128
130
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
R273A
R273A
1
1
0
0
273
R
A
7
CONSERVATION
2ZTA
320
null
273
A|B
H
false
false
129.688267
49.395909
227
ProTherm
7
CD
Thermal
sodium phosphate
10 mM
null
2ZTA_A:R25A
37
null
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes
TM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
18
ARTICLE
An intrahelical salt bridge within the trigger site stabilizes the GCN4 leucine zipper.
2,001
10.1074/jbc.M010492200
11134036
J Biol Chem;276;13685-8
6
Frank S|Schulthess T|Landwehr R|Lustig A|Kammerer R A|Jaravine V A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"2ZTA_A:R25A","typ...
[{"datasets":[],"id":945,"numValue":37.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":946,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
[{"id":8383,"numValue":7.0,"position":273,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7994
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,994
train
mutant
115
128
130
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
R273A
R273A
1
1
0
0
273
R
A
7
CONSERVATION
2ZTA
320
null
273
A|B
H
false
false
129.688267
49.395909
13,772
ProTherm
7
CD
Urea
Sodium phosphate
50mM
15
NaCl
150 mM
2ZTA_A:R25A
null
null
8.44
1.66
null
null
null
null
0.98
null
null
null
null
null
null
null
Unknown
DG|DDG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
867
ARTICLE
Salt-bridges can stabilize but do not accelerate the folding of the homodimeric coiled-coil peptide GCN4-p1.
2,004
10.1016/j.jmb.2003.12.069
15037063
J Mol Biol;336;989-96
3
Matthews C Robert|Ibarra-Molero Beatriz|Zitzewitz Jill A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":15.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50mM","type":"BUFFE...
[{"datasets":[],"id":50837,"numValue":8.44,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":50838,"numValue":1.66,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":50839,"numValue":0.98,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":50840,"numValue":null,"references":[],...
[{"id":8383,"numValue":7.0,"position":273,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7995
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,995
train
mutant
6,395
128
7,029
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
K275A
K275A
1
1
0
0
275
K
A
6
CONSERVATION
2ZTA
320
null
275
A|B
H
false
false
101.848783
50
13,773
ProTherm
7
CD
Urea
Sodium phosphate
50mM
15
NaCl
150 mM
2ZTA_A:K27A
null
null
9.19
0.91
null
null
null
null
0.96
null
null
null
null
null
null
null
Unknown
DG|DDG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
867
ARTICLE
Salt-bridges can stabilize but do not accelerate the folding of the homodimeric coiled-coil peptide GCN4-p1.
2,004
10.1016/j.jmb.2003.12.069
15037063
J Mol Biol;336;989-96
3
Matthews C Robert|Ibarra-Molero Beatriz|Zitzewitz Jill A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":15.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50mM","type":"BUFFE...
[{"datasets":[],"id":50841,"numValue":9.19,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":50842,"numValue":0.91,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":50843,"numValue":0.96,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":50844,"numValue":null,"references":[],...
[{"id":8385,"numValue":6.0,"position":275,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7996
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,996
train
mutant
6,396
128
7,030
281
281
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
15
General control transcription factor GCN4
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
1
P03069
IPR050946|IPR004827|IPR046347
K276A
K276A
1
1
0
0
276
K
A
6
CONSERVATION
2ZTA
320
null
276
A|B
H
false
false
162.732222
58.008333
13,774
ProTherm
7
CD
Urea
Sodium phosphate
50mM
15
NaCl
150 mM
2ZTA_A:K28A
null
null
10.04
0.06
null
null
null
null
0.88
null
null
null
null
null
null
null
Unknown
DG|DDG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
867
ARTICLE
Salt-bridges can stabilize but do not accelerate the folding of the homodimeric coiled-coil peptide GCN4-p1.
2,004
10.1016/j.jmb.2003.12.069
15037063
J Mol Biol;336;989-96
3
Matthews C Robert|Ibarra-Molero Beatriz|Zitzewitz Jill A
[{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":15.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"Sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50mM","type":"BUFFE...
[{"datasets":[],"id":50845,"numValue":10.04,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":50846,"numValue":0.06,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":50847,"numValue":0.88,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":50848,"numValue":null,"references":[]...
[{"id":8386,"numValue":6.0,"position":276,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:7997
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,997
train
sequence
131
131
-1
211
-1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
0
0
0
0
-1
null
null
false
false
null
null
22,106
ProTherm
6
CD
Thermal
phosphate
50 mM
null
Na2SO4
0.4 M
63.7
null
null
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
TM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"Na2SO4","type":"ION"},{"...
[{"datasets":[],"id":80016,"numValue":63.7,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":80017,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
fireprotdb:7999
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
7,999
train
sequence
131
131
-1
211
-1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
0
0
0
0
-1
null
null
false
false
null
null
22,542
ProTherm
6
CD
Thermal
sodium phosphate
50 mM
null
Na2SO4
0.4 M
60.1
null
null
null
null
null
33.1
null
null
null
null
null
null
null
null
null
yes
TM|DHVH|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
1619
ARTICLE
Cooperative interactions and a non-native buried Trp in the unfolded state of an SH3 domain.
2,002
10.1016/s0022-2836(02)00741-6
12215422
J Mol Biol;322;163-78
3
Crowhurst Karin A|Tollinger Martin|Forman-Kay Julie D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"Na2SO4","type":"I...
[{"datasets":[],"id":81261,"numValue":60.1,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81262,"numValue":33.1,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":81263,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
fireprotdb:8000
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,000
train
sequence
131
131
-1
211
-1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
0
0
0
0
-1
null
null
false
false
null
null
25,544
ProTherm
6
CD
Thermal
phosphate
50 mM
25
Na2SO4
0.4 M
null
null
1.8
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_C...
[{"datasets":[],"id":89810,"numValue":1.8,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":89811,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
fireprotdb:8001
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,001
train
sequence
131
131
-1
211
-1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
0
0
0
0
-1
null
null
false
false
null
null
27,348
ProTherm
6
Fluorescence
GdnHCl
sodium phosphate
50 mM
5
Na2SO4
0.4 M
null
null
2.18
null
null
null
null
null
1.39
null
null
null
null
null
null
null
yes
DG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
1619
ARTICLE
Cooperative interactions and a non-native buried Trp in the unfolded state of an SH3 domain.
2,002
10.1016/s0022-2836(02)00741-6
12215422
J Mol Biol;322;163-78
3
Crowhurst Karin A|Tollinger Martin|Forman-Kay Julie D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":5.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","...
[{"datasets":[],"id":95934,"numValue":2.18,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":95935,"numValue":1.39,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":95936,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
fireprotdb:8002
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,002
train
sequence
131
131
-1
211
-1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
0
0
0
0
-1
null
null
false
false
null
null
27,349
ProTherm
6
CD
GdnHCl
sodium phosphate
50 mM
5
null
null
1.47
null
null
null
null
null
3.48
null
null
null
null
null
null
null
yes
DG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC
1619
ARTICLE
Cooperative interactions and a non-native buried Trp in the unfolded state of an SH3 domain.
2,002
10.1016/s0022-2836(02)00741-6
12215422
J Mol Biol;322;163-78
3
Crowhurst Karin A|Tollinger Martin|Forman-Kay Julie D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":5.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUF...
[{"datasets":[],"id":95937,"numValue":1.47,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":95938,"numValue":3.48,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":95939,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
fireprotdb:8003
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,003
train
mutant
116
131
132
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22G
T22G
1
1
0
0
22
T
G
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
228
ProTherm
6
CD
Thermal
phosphate
50 mM
null
Na2SO4
0.4 M
2A36_A:T22G
84.8
21.1
null
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"Na2SO4","type":"ION"},{"...
[{"datasets":[],"id":947,"numValue":84.8,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":948,"numValue":21.1,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":949,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8004
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,004
train
mutant
116
131
132
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22G
T22G
1
1
0
0
22
T
G
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
8,606
ProTherm
6
CD
Thermal
phosphate
50 mM
25
Na2SO4
0.4 M
2A36_A:T22G
null
null
4.2
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_C...
[{"datasets":[],"id":29206,"numValue":4.2,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":29207,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8005
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,005
train
mutant
116
131
132
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22G
T22G
1
1
0
0
22
T
G
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
12,997
ProTherm
6
Fluorescence
GdnHCl
phosphate
50 mM
20
2A36_A:T22G
null
null
4
-3.6
null
null
null
null
2.2
null
null
null
null
null
null
null
Unknown
DG|DDG|M|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION
194
ARTICLE
P61A mutation in the factor for inversion stimulation results in a thermostable dimeric intermediate.
2,005
10.1021/bi050640k
16274219
Biochemistry;44;14715-24
3
Meinhold Derrick|Boswell Sarah|Col?n Wilfredo
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":20.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":...
[{"datasets":[],"id":47457,"numValue":4.0,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":47458,"numValue":-3.6,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":47459,"numValue":2.2,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":47460,"numValue":null,"references":[],"s...
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8006
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,006
train
mutant
117
131
133
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22D
T22D
1
1
0
0
22
T
D
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
229
ProTherm
6
CD
Thermal
phosphate
50 mM
null
Na2SO4
0.4 M
2A36_A:T22D
73.1
9.4
null
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"Na2SO4","type":"ION"},{"...
[{"datasets":[],"id":950,"numValue":73.1,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":951,"numValue":9.4,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":952,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8007
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,007
train
mutant
117
131
133
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22D
T22D
1
1
0
0
22
T
D
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
8,607
ProTherm
6
CD
Thermal
phosphate
50 mM
25
Na2SO4
0.4 M
2A36_A:T22D
null
null
3.3
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_C...
[{"datasets":[],"id":29208,"numValue":3.3,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":29209,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8009
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,009
train
mutant
118
131
134
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22N
T22N
1
1
0
0
22
T
N
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
8,608
ProTherm
6
CD
Thermal
phosphate
50 mM
25
Na2SO4
0.4 M
2A36_A:T22N
null
null
3.1
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_C...
[{"datasets":[],"id":29210,"numValue":3.1,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":29211,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8010
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,010
train
mutant
119
131
135
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22F
T22F
1
1
0
0
22
T
F
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
231
ProTherm
6
CD
Thermal
phosphate
50 mM
null
Na2SO4
0.4 M
2A36_A:T22F
66.7
3
null
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"Na2SO4","type":"ION"},{"...
[{"datasets":[],"id":956,"numValue":66.7,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":957,"numValue":3.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":958,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8011
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,011
train
mutant
119
131
135
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22F
T22F
1
1
0
0
22
T
F
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
8,609
ProTherm
6
CD
Thermal
phosphate
50 mM
25
Na2SO4
0.4 M
2A36_A:T22F
null
null
3.1
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_C...
[{"datasets":[],"id":29212,"numValue":3.1,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":29213,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8012
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,012
train
mutant
120
131
136
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22S
T22S
1
1
0
0
22
T
S
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
232
ProTherm
6
CD
Thermal
phosphate
50 mM
null
Na2SO4
0.4 M
2A36_A:T22S
63.5
-0.2
null
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"Na2SO4","type":"ION"},{"...
[{"datasets":[],"id":959,"numValue":63.5,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":960,"numValue":-0.2,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":961,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8013
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,013
train
mutant
120
131
136
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22S
T22S
1
1
0
0
22
T
S
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
8,610
ProTherm
6
CD
Thermal
phosphate
50 mM
25
Na2SO4
0.4 M
2A36_A:T22S
null
null
2.4
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_C...
[{"datasets":[],"id":29214,"numValue":2.4,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":29215,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8014
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,014
train
mutant
121
131
137
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22A
T22A
1
1
0
0
22
T
A
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
233
ProTherm
6
CD
Thermal
phosphate
50 mM
null
Na2SO4
0.4 M
2A36_A:T22A
66.9
3.2
null
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"Na2SO4","type":"ION"},{"...
[{"datasets":[],"id":962,"numValue":66.9,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":963,"numValue":3.2,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":964,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8015
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,015
train
mutant
121
131
137
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22A
T22A
1
1
0
0
22
T
A
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
8,611
ProTherm
6
CD
Thermal
phosphate
50 mM
25
Na2SO4
0.4 M
2A36_A:T22A
null
null
2.2
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_C...
[{"datasets":[],"id":29216,"numValue":2.2,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":29217,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8016
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,016
train
mutant
122
131
138
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22L
T22L
1
1
0
0
22
T
L
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
234
ProTherm
6
CD
Thermal
phosphate
50 mM
null
Na2SO4
0.4 M
2A36_A:T22L
58
-5.7
null
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"Na2SO4","type":"ION"},{"...
[{"datasets":[],"id":965,"numValue":58.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":966,"numValue":-5.7,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":967,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8018
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,018
train
mutant
123
131
139
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22K
T22K
1
1
0
0
22
T
K
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
235
ProTherm
6
CD
Thermal
phosphate
50 mM
null
Na2SO4
0.4 M
2A36_A:T22K
65
1.3
null
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"Na2SO4","type":"ION"},{"...
[{"datasets":[],"id":968,"numValue":65.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":969,"numValue":1.3,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":970,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8019
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,019
train
mutant
123
131
139
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22K
T22K
1
1
0
0
22
T
K
5
CONSERVATION
2A36
79
null
22
A
T
false
false
73.623969
null
8,613
ProTherm
6
CD
Thermal
phosphate
50 mM
25
Na2SO4
0.4 M
2A36_A:T22K
null
null
1.8
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_C...
[{"datasets":[],"id":29220,"numValue":1.8,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":29221,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8020
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,020
train
mutant
7,293
131
7,963
211
211
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
16
Growth factor receptor-bound protein 2
Drosophila melanogaster
1
Q08012
IPR043539|IPR000980|IPR036860|IPR036028|IPR001452
T22G|Q23D
T22G|Q23D
2
2
0
0
22
T
G
5
CONSERVATION
2A36
79
null
22|23
A
T|E
true
false
65.800627
null
15,650
ProTherm
6
CD
Thermal
phosphate
50 mM
null
Na2SO4
0.4 M
2A36_A:T22G 2A36_A:Q23D
88.9
25.2
null
null
null
null
null
null
null
null
null
null
null
null
null
null
Unknown
TM|DTM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION
19
ARTICLE
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states.
2,001
10.1006/jmbi.2001.4521
11273710
J Mol Biol;307;913-28
4
Mok Y K|Elisseeva E L|Davidson A R|Forman-Kay J D
[{"numValue":6.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"Na2SO4","type":"ION"},{"...
[{"datasets":[],"id":57436,"numValue":88.9,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57437,"numValue":25.2,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57438,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}]
[{"id":8413,"numValue":5.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":8414,"numValue":5.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}]
fireprotdb:8021
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,021
train
sequence
142
142
-1
155
-1
17
Fibroblast growth factor 1
Homo sapiens
1
17
Fibroblast growth factor 1
Homo sapiens
1
P05230
IPR002209|IPR008996
0
0
0
0
-1
null
null
false
false
null
null
19,735
ProTherm
6.6
DSC
Thermal
GuHCl/ADA
0.7 M
null
39.45
null
null
null
61.5
null
null
null
null
null
null
null
null
null
null
null
yes
TM|DH|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC
395
ARTICLE
Thermodynamic characterization of mutants of human fibroblast growth factor 1 with an increased physiological half-life.
2,000
10.1021/bi9927742
10852713
Biochemistry;39;7153-8
4
Blaber M|Khurana A|Culajay J F|Blaber S I
[{"numValue":6.6,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"GuHCl/ADA","type":"BUFFER"},{"numValue":null,"strValue":"0.7 M","type":"BUFFER_CONC"}]
[{"datasets":[],"id":72560,"numValue":39.45,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":72561,"numValue":61.5,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":72562,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
fireprotdb:8022
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,022
train
sequence
142
142
-1
155
-1
17
Fibroblast growth factor 1
Homo sapiens
1
17
Fibroblast growth factor 1
Homo sapiens
1
P05230
IPR002209|IPR008996
0
0
0
0
-1
null
null
false
false
null
null
19,736
ProTherm
6.6
DSC
Thermal
GuHCl/ADA
0.7 M
null
25
null
null
null
null
null
null
null
null
null
null
null
null
null
null
null
yes
TM|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC
395
ARTICLE
Thermodynamic characterization of mutants of human fibroblast growth factor 1 with an increased physiological half-life.
2,000
10.1021/bi9927742
10852713
Biochemistry;39;7153-8
4
Blaber M|Khurana A|Culajay J F|Blaber S I
[{"numValue":6.6,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"GuHCl/ADA","type":"BUFFER"},{"numValue":null,"strValue":"0.7 M","type":"BUFFER_CONC"}]
[{"datasets":[],"id":72563,"numValue":25.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":72564,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
fireprotdb:8023
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,023
train
sequence
142
142
-1
155
-1
17
Fibroblast growth factor 1
Homo sapiens
1
17
Fibroblast growth factor 1
Homo sapiens
1
P05230
IPR002209|IPR008996
0
0
0
0
-1
null
null
false
false
null
null
21,314
ProTherm
6.6
DSC
GdnHCl
GuHCl/ADA
0.7 M
25
null
null
4.97
null
null
null
null
null
null
null
null
null
null
null
null
null
yes
DG|REVERSIBILITY
PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC
395
ARTICLE
Thermodynamic characterization of mutants of human fibroblast growth factor 1 with an increased physiological half-life.
2,000
10.1021/bi9927742
10852713
Biochemistry;39;7153-8
4
Blaber M|Khurana A|Culajay J F|Blaber S I
[{"numValue":6.6,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"GuHCl/ADA","type":"BUFFER"},{"numValue":null,"strValue":"0.7 M","type":"BUFFER_C...
[{"datasets":[],"id":77540,"numValue":4.97,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":77541,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}]
fireprotdb:8024
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,024
train
sequence
142
142
-1
155
-1
17
Fibroblast growth factor 1
Homo sapiens
1
17
Fibroblast growth factor 1
Homo sapiens
1
P05230
IPR002209|IPR008996
0
0
0
0
-1
null
null
false
false
null
null
22,108
ProTherm
6.6
DSC
Thermal
N-(2-acetamido)iminodiacetic acid(ADA)
20 mM
null
NaCl
100 mM
40.05
null
null
null
62.38
null
56.14
null
null
null
null
null
null
null
null
null
yes
TM|DH|DHVH|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC
20
ARTICLE
Stabilization of hen egg white lysozyme by a cavity-filling mutation.
2,001
10.1110/ps.37401
11266617
Protein Sci;10;313-20
5
Ueda T|Imoto T|Ohmura T|Ootsuka K|Saito M
[{"numValue":6.6,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"N-(2-acetamido)iminodiacetic acid(ADA)","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type":"BUFFER_CONC"},{"numValue":null,"strVa...
[{"datasets":[],"id":80020,"numValue":40.05,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":80021,"numValue":62.38,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":80022,"numValue":56.14,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":80023,"numValue":null,"references...
fireprotdb:8025
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,025
train
sequence
142
142
-1
155
-1
17
Fibroblast growth factor 1
Homo sapiens
1
17
Fibroblast growth factor 1
Homo sapiens
1
P05230
IPR002209|IPR008996
0
0
0
0
-1
null
null
false
false
null
null
22,995
ProTherm
7.3
Fluorescence
Thermal
H3PO4
25 mM
null
39.8
null
null
null
null
null
66.2
null
null
null
null
null
null
null
null
null
Yes
TM|DHVH|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC
180
ARTICLE
Design of fully active FGF-1 variants with increased stability.
2,004
10.1093/protein/gzh076
15469994
Protein Eng Des Sel;17;603-11
4
Krowarsch Daniel|Otlewski Jacek|Zakrzewska Malgorzata|Wiedlocha Antoni
[{"numValue":7.3,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"H3PO4","type":"BUFFER"},{"numValue":null,"strValue":"25 mM","type":"BUFFER_CONC"}]
[{"datasets":[],"id":82609,"numValue":39.8,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":82610,"numValue":66.2,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":82611,"numValue":null,"references":[],"strValue":"Yes","type":"REVERSIBILITY"}]
fireprotdb:8026
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,026
train
sequence
142
142
-1
155
-1
17
Fibroblast growth factor 1
Homo sapiens
1
17
Fibroblast growth factor 1
Homo sapiens
1
P05230
IPR002209|IPR008996
0
0
0
0
-1
null
null
false
false
null
null
22,996
ProTherm
7.3
CD
Thermal
H3PO4
25 mM
null
40.7
null
null
null
null
null
67.7
null
null
null
null
null
null
null
null
null
Yes
TM|DHVH|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER|BUFFER_CONC
180
ARTICLE
Design of fully active FGF-1 variants with increased stability.
2,004
10.1093/protein/gzh076
15469994
Protein Eng Des Sel;17;603-11
4
Krowarsch Daniel|Otlewski Jacek|Zakrzewska Malgorzata|Wiedlocha Antoni
[{"numValue":7.3,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"H3PO4","type":"BUFFER"},{"numValue":null,"strValue":"25 mM","type":"BUFFER_CONC"}]
[{"datasets":[],"id":82612,"numValue":40.7,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":82613,"numValue":67.7,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":82614,"numValue":null,"references":[],"strValue":"Yes","type":"REVERSIBILITY"}]
fireprotdb:8027
fireprotdb
LiteFold/FireProtDB
labeled/fireprotdb/fireprotdb_search_all.jsonl
tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl
79354b4f8754e21c3eb41aaf3dd63ba34ae750cd
8,027
train
sequence
142
142
-1
155
-1
17
Fibroblast growth factor 1
Homo sapiens
1
17
Fibroblast growth factor 1
Homo sapiens
1
P05230
IPR002209|IPR008996
0
0
0
0
-1
null
null
false
false
null
null
23,861
ProTherm
6.6
DSC
Thermal
ADA (N-(2-acetamide)iminodiaceticacid)
null
39.75
null
null
null
65.73
null
null
null
null
null
null
null
null
null
null
null
Yes (>80%)
TM|DH|REVERSIBILITY
PH|MEASURE|METHOD|BUFFER
235
ARTICLE
The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
2,009
10.1016/j.jmb.2009.08.026
19695265
J Mol Biol;393;113-27
2
Lee Jihun|Blaber Michael
[{"numValue":6.6,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"ADA (N-(2-acetamide)iminodiaceticacid)","type":"BUFFER"}]
[{"datasets":[],"id":85151,"numValue":39.75,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":85152,"numValue":65.73,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":85153,"numValue":null,"references":[],"strValue":"Yes (>80%)","type":"REVERSIBILITY"}]