LiteFold/GO · Datasets at Hugging Face

GO:0000138

138

Golgi trans cisterna

cellular_component

The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed.

[ "ISBN:0815316194" ]

null

[ "late Golgi" ]

[ "RELATED" ]

[]

[ "GO:0031985" ]

[]

[ "GO:0031985" ]

[]

null

false

true

7

GO:0000139

139

Golgi membrane

cellular_component

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

[ "GOC:mah" ]

null

[ "Golgi apparatus membrane" ]

[ "EXACT" ]

[]

[ "GO:0098588" ]

[ "part_of GO:0005794" ]

[ "part_of" ]

[ "GO:0005794" ]

[ "GO:0005794", "GO:0098588" ]

[]

null

false

true

8

GO:0000140

140

acylglycerone-phosphate reductase (NADP+) activity

molecular_function

Catalysis of the reaction: 1-hexadecanoyl-sn-glycero-3-phosphate + NADP+ = 1-hexadecanoylglycerone 3-phosphate + H+ + NADPH.

[ "RHEA:17341" ]

null

[ "1-acyldihydroxyacetone-phosphate reductase activity", "1-palmitoylglycerol-3-phosphate:NADP+ oxidoreductase activity", "acyldihydroxyacetone phosphate reductase activity", "palmitoyl dihydroxyacetone phosphate reductase activity", "palmitoyl-dihydroxyacetone-phosphate reductase activity", "palmitoyldihyd...

[ "EXACT", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED" ]

[]

[ "EC:1.1.1.101", "MetaCyc:ACYLGLYCERONE-PHOSPHATE-REDUCTASE-RXN", "MetaCyc:RXN-15046", "Reactome:R-HSA-75883 \"DHRS7B reduces GO3P to HXDG3P\"", "RHEA:17341", "RHEA:36175" ]

[ "GO:0016616" ]

[]

[ "GO:0016616" ]

[]

[ "skos:exactMatch EC:1.1.1.101", "skos:exactMatch MetaCyc:ACYLGLYCERONE-PHOSPHATE-REDUCTASE-RXN", "skos:exactMatch RHEA:17341", "skos:narrowMatch MetaCyc:RXN-15046", "skos:narrowMatch RHEA:36175", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28070\" xsd:anyURI", "term_tracker_i...

null

false

true

3

GO:0000142

142

cellular bud neck contractile ring

cellular_component

A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane at the mother-bud neck in mitotic cells that divide by budding in preparation for completing cytokinesis. An example of this structure is found in Saccharomyces cerevisiae.

[ "GOC:krc", "PMID:16009555" ]

null

[ "neck ring" ]

[ "EXACT" ]

[]

[ "GO:0110085" ]

[ "part_of GO:0005935" ]

[ "part_of" ]

[ "GO:0005935" ]

[ "GO:0005935", "GO:0110085" ]

[ "GO:0005826", "part_of GO:0005935" ]

[]

null

false

true

3

GO:0000144

144

cellular bud neck septin ring

cellular_component

A ring-shaped structure that forms at the site of cytokinesis in the bud neck of a budding cell; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. In S. cerevisiae, this structure forms at the time of bud emergence and the septins show a high ...

[ "GOC:krc", "PMID:16009555" ]

null

[]

[ "GO:0000399", "GO:0005940", "GO:0032161" ]

[]

[ "GO:0000399", "GO:0005940", "GO:0032161" ]

[ "GO:0005940", "part_of GO:0005935" ]

[]

null

false

true

9

GO:0000145

145

exocyst

cellular_component

A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals.

[ "GOC:cilia", "PMID:15292201", "PMID:27243008", "PMID:9700152" ]

null

[ "exocyst complex", "Sec6/8 complex" ]

[ "EXACT", "EXACT" ]

[]

[ "Wikipedia:Exocyst" ]

[ "GO:0099023" ]

[ "part_of GO:0005938" ]

[ "part_of" ]

[ "GO:0005938" ]

[ "GO:0005938", "GO:0099023" ]

[]

null

false

true

5

GO:0000146

146

microfilament motor activity

molecular_function

A motor activity that generates movement along a microfilament, driven by ATP hydrolysis.

[ "PMID:29716949" ]

null

[ "actin filament motor activity", "actin-activated ATPase activity", "actin-dependent ATPase activity", "actin-filament motor activity", "muscle motor activity", "myosin ATPase activity" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "NARROW", "RELATED" ]

[ "GO:0030898" ]

[]

[ "EC:5.6.1.8", "Reactome:R-HSA-2316352 \"SLC2A4 (GLUT4) vesicle translocates and docks at the plasma membrane\"", "Reactome:R-HSA-432237 \"Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane\"", "Reactome:R-HSA-9023171 \"Insulin secretory granule translocates across the corti...

[ "GO:0003774", "GO:0120544", "GO:0140657" ]

[]

[ "GO:0003774", "GO:0120544", "GO:0140657" ]

[]

[ "skos:exactMatch EC:5.6.1.8", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20877\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29690\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI", ...

null

false

true

8

GO:0000147

147

actin cortical patch assembly

biological_process

Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.

[ "GOC:mah" ]

null

[]

[ "GO:0022607", "GO:0030866", "GO:0044396" ]

[]

[ "GO:0022607", "GO:0030866", "GO:0044396" ]

[]

null

false

true

2

GO:0000148

148

1,3-beta-D-glucan synthase complex

cellular_component

A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a (1->3)-beta-D-glucan chain.

[ "PMID:7983071" ]

null

[ "(1->3)-beta-glucan synthase complex", "1,3-beta-glucan synthase complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:1990234" ]

[]

[ "GO:1990234" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28315\" xsd:anyURI" ]

null

false

true

2

GO:0000149

149

SNARE binding

molecular_function

Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.

[ "PMID:12642621" ]

null

[ "SNAP receptor binding" ]

[ "EXACT" ]

[]

[ "goslim_chembl" ]

[ "Reactome:R-HSA-210426 \"Glutamate synaptic vesicle docking and priming\"", "Reactome:R-HSA-210430 \"Release of L-Glutamate at the synapse\"", "Reactome:R-HSA-265166 \"Exocytosis of Insulin\"", "Reactome:R-HSA-372505 \"Acetylcholine synaptic vesicle docking and priming\"", "Reactome:R-HSA-372529 \"Release o...

[ "GO:0005515" ]

[]

[ "GO:0005515" ]

[]

null

false

true

5

GO:0000150

150

DNA strand exchange activity

molecular_function

Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.

[ "GOC:elh" ]

Note that this term represents activities that do not break or form phosphodiester bonds, and is therefore not a parent of 'site-specific recombinase activity ; GO:0009009'.

[ "RecA-family recombinase activity", "recombinase activity", "strand exchange activity", "strand transferase" ]

[ "RELATED", "EXACT", "RELATED", "NARROW" ]

[]

[ "goslim_metagenomics" ]

[ "Reactome:R-HSA-912458 \"Formation of meiotic heteroduplex\"" ]

[ "GO:0140097" ]

[ "part_of GO:0006310" ]

[ "part_of" ]

[ "GO:0006310" ]

[ "GO:0006310", "GO:0140097" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20964\" xsd:anyURI" ]

null

false

true

8

GO:0000151

151

ubiquitin ligase complex

cellular_component

A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.

[ "GOC:jh2", "PMID:9529603" ]

null

[]

[ "goslim_pir" ]

[]

[ "GO:0140535", "GO:1990234" ]

[]

[ "GO:0140535", "GO:1990234" ]

[]

null

false

true

1

GO:0000152

152

nuclear ubiquitin ligase complex

cellular_component

A ubiquitin ligase complex found in the nucleus.

[ "GOC:mah" ]

null

[]

[ "GO:0000151", "GO:0140513" ]

[]

[ "GO:0000151", "GO:0140513" ]

[ "GO:0000151", "part_of GO:0005634" ]

[]

null

false

true

4

GO:0000153

153

cytoplasmic ubiquitin ligase complex

cellular_component

A ubiquitin ligase complex found in the cytoplasm.

[ "GOC:mah" ]

null

[]

[ "GO:0000151" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0000151", "GO:0005737" ]

[ "GO:0000151", "part_of GO:0005737" ]

[]

null

false

true

2

GO:0000154

154

rRNA modification

biological_process

The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically.

[ "GOC:curators" ]

The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specifi...

[ "rRNA editing" ]

[ "NARROW" ]

[ "GO:0016548" ]

[]

[ "Reactome:R-HSA-6790901 \"rRNA modification in the nucleus and cytosol\"", "Reactome:R-HSA-6793080 \"rRNA modification in the mitochondrion\"" ]

[ "GO:0006364", "GO:0009451" ]

[]

[ "GO:0006364", "GO:0009451" ]

[]

null

false

true

2

GO:0000155

155

phosphorelay sensor kinase activity

molecular_function

Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. T...

[ "GOC:bf", "GOC:mcc", "PMID:10966457", "PMID:20223701", "PMID:31386843", "PMID:9191038" ]

null

[ "two-component sensor activity", "two-component sensor molecule", "two-component system sensor activity" ]

[ "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:0004673", "GO:0140299" ]

[ "part_of GO:0000160" ]

[ "part_of" ]

[ "GO:0000160" ]

[ "GO:0000160", "GO:0004673", "GO:0140299" ]

[]

[ "skos:broadMatch EC:2.7.13.3", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28061\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]

null

false

true

9

GO:0000156

156

phosphorelay response regulator activity

molecular_function

Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulato...

[ "GOC:bf", "PMID:10966457", "PMID:11842140" ]

null

[ "two-component response regulator activity" ]

[ "NARROW" ]

[]

[ "GO:0060089" ]

[ "part_of GO:0000160" ]

[ "part_of" ]

[ "GO:0000160" ]

[ "GO:0000160", "GO:0060089" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/15611\" xsd:anyURI" ]

null

false

true

9

GO:0000159

159

protein phosphatase type 2A complex

cellular_component

A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regula...

[ "GOC:mah", "ISBN:0198547684", "PMID:17245430" ]

null

[ "PP2A complex", "PP2A-pi", "PP2a-protector", "protein phosphatase 2 complex" ]

[ "EXACT", "NARROW", "NARROW", "RELATED" ]

[]

[ "GO:0008287" ]

[]

[ "GO:0008287" ]

[]

null

false

true

3

GO:0000161

161

obsolete osmosensory signaling MAPK cascade

biological_process

OBSOLETE. A MAPK cascade that starts with the activation of a Ssk2/Win1 family MAP3K, which activates a Pbs2/Wis1 family MAP2K, resulting in the activation of a Hog1/Sty1 family MAPK. Hog1 then translocates from the cytosol into the nucleus where it affects the expression of a large number of genes. This cascade is act...

[ "PMID:17604854", "PMID:32794416", "PMID:9561267" ]

This term was obsoleted because it represents the same process as p38MAPK cascade ; GO:0038066.

[ "activation of MAPK activity involved in osmosensory signaling pathway", "activation of MAPKK activity during osmolarity sensing", "activation of MAPKK activity involved in osmosensory signaling pathway", "activation of MAPKKK activity during osmolarity sensing", "activation of MAPKKK activity involved in o...

[ "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "EXACT", "EXACT", "EXACT", "EXACT", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "EXACT", "NARROW" ]

[ "GO:0000167", "GO:0000168", "GO:0000169", "GO:0000173", "GO:0007233" ]

[]

[ "GO:0038066" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20380\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26610\" xsd:anyURI" ]

null

true

7

GO:0000162

162

L-tryptophan biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of L-tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; L-tryptophan is synthesized from chorismate via anthranilate.

[ "GOC:mah", "ISBN:0471331309", "MetaCyc:TRPSYN-PWY" ]

null

[ "aromatic amino acid family biosynthetic process, anthranilate pathway", "L-tryptophan anabolism", "L-tryptophan biosynthesis", "tryptophan biosynthetic process", "tryptophan formation", "tryptophan synthesis" ]

[ "EXACT", "EXACT", "EXACT", "RELATED", "EXACT", "RELATED" ]

[ "GO:0009096" ]

[]

[ "MetaCyc:TRPSYN-PWY" ]

[ "GO:0006568", "GO:0009073", "GO:0046219", "GO:1902223" ]

[]

[ "GO:0006568", "GO:0009073", "GO:0046219", "GO:1902223" ]

[]

null

false

true

9

GO:0000164

164

protein phosphatase type 1 complex

cellular_component

A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity.

[ "GOC:mah", "GOC:ssd" ]

null

[]

[ "GO:0008287" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0005737", "GO:0008287" ]

[]

null

false

true

4

GO:0000165

165

MAPK cascade

biological_process

An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the down...

[ "PMID:20811974", "PMID:9561267" ]

MAPK cascades lie downstream of many cell surface receptors and cooperate in transmitting various extracellular signals to the nucleus. One way by which the specificity of each cascade is regulated is through the existence of several distinct components in each tier of the different cascades. The cascades are typically...

[ "ERK/MAPK cascade", "MAP kinase cascade", "MAP kinase kinase kinase cascade", "MAPK signal transduction", "MAPK signaling", "MAPK signalling", "MAPKKK cascade", "MAPKKK cascade during sporulation", "mitogen-activated protein kinase cascade" ]

[ "NARROW", "EXACT", "EXACT", "EXACT", "RELATED", "RELATED", "EXACT", "NARROW", "EXACT" ]

[ "GO:0007255" ]

[]

[ "Reactome:R-HSA-169893 \"Prolonged ERK activation events\"", "Reactome:R-HSA-5673001 \"RAF/MAP kinase cascade\"", "Wikipedia:MAPK_cascade", "Wikipedia:Mitogen-activated_protein_kinase" ]

[ "GO:0141124" ]

[]

[ "GO:0141124" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26806\" xsd:anyURI" ]

null

false

true

4

GO:0000166

166

nucleotide binding

molecular_function

Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.

[ "GOC:mah", "ISBN:0198547684" ]

null

[]

[ "goslim_chembl", "goslim_metagenomics", "goslim_pir", "goslim_plant" ]

[]

[ "GO:1901265", "GO:1901363" ]

[]

[ "GO:1901265", "GO:1901363" ]

[]

null

false

true

2

GO:0000170

170

obsolete sphingosine hydroxylase activity

molecular_function

OBSOLETE. Catalysis of the hydroxylation of sphingolipid long chain bases.

[ "PMID:9556590" ]

The reason for obsoletion is that this term is equivalent to sphingolipid C4-monooxygenase activity.

[]

[ "GO:0102772" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29717\" xsd:anyURI" ]

null

true

8

GO:0000171

171

ribonuclease MRP activity

molecular_function

Catalysis of the site-specific cleavage of RNA by a catalytic RNA-mediated mechanism; substrates include the A3 site in the ITS1 of pre-rRNA.

[ "PMID:17881380" ]

null

[ "RNase MRP" ]

[ "EXACT" ]

[]

[ "Wikipedia:RNase_MRP" ]

[ "GO:0004521", "GO:0016788" ]

[]

[ "GO:0004521", "GO:0016788" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22261\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24408\" xsd:anyURI" ]

null

false

true

4

GO:0000172

172

ribonuclease MRP complex

cellular_component

A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the ...

[ "GOC:sgd_curators", "PMID:10690410", "PMID:14729943", "PMID:7510714" ]

null

[ "ribonuclease mitochondrial RNA processing complex", "RNase MRP complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0005732", "GO:1902555" ]

[]

[ "GO:0005732", "GO:1902555" ]

[]

null

false

true

1

GO:0000174

174

obsolete inactivation of MAPK (mating sensu Saccharomyces)

biological_process

OBSOLETE. Downregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces.

[ "PMID:9561267" ]

This term was made obsolete because it is a gene product specific term.

[ "inactivation of MAPK (mating sensu Saccharomyces)" ]

[ "EXACT" ]

[]

[ "GO:0000750" ]

[]

null

true

8

GO:0000175

175

3'-5'-RNA exonuclease activity

molecular_function

Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.

[ "GOC:mah", "ISBN:0198547684" ]

null

[ "3'-5' exoribonuclease activity", "3'-5'-exoribonuclease activity" ]

[ "EXACT", "EXACT" ]

[]

[ "Reactome:R-HSA-430028 \"Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion\"", "Reactome:R-HSA-6791222 \"21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA\"", "Reactome:R-HSA-9682603 \"nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotide...

[ "GO:0008408", "GO:0016896" ]

[]

[ "GO:0008408", "GO:0016896" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28062\" xsd:anyURI" ]

null

false

true

9

GO:0000176

176

nuclear exosome (RNase complex)

cellular_component

A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RN...

[ "PMID:17174896", "PMID:20531386", "PMID:26726035" ]

null

[ "eukaryotic exosome multienzyme ribonuclease complex", "nuclear exosome (ribonuclease complex)", "nuclear exosome multienzyme ribonuclease complex" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0000178", "GO:0140513" ]

[ "part_of GO:0031981" ]

[ "part_of" ]

[ "GO:0031981" ]

[ "GO:0000178", "GO:0031981", "GO:0140513" ]

[ "GO:0000178", "part_of GO:0005634" ]

[]

null

false

true

2

GO:0000177

177

cytoplasmic exosome (RNase complex)

cellular_component

A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular...

[ "PMID:17174896", "PMID:20531386", "PMID:26726035" ]

null

[ "cytoplasmic exosome (ribonuclease complex)", "cytoplasmic exosome multienzyme ribonuclease complex", "prokaryotic exosome multienzyme ribonuclease complex" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0000178" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0000178", "GO:0005737" ]

[ "GO:0000178", "part_of GO:0005737" ]

[]

null

false

true

7

GO:0000178

178

exosome (RNase complex)

cellular_component

A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing l...

[ "PMID:17174896", "PMID:20531386", "PMID:26726035" ]

Note that this term should not be confused with 'exosome' used in the context of vesicles released from multivesicular bodies.

[ "exosome (ribonucleasease complex)", "exosome multienzyme ribonuclease complex" ]

[ "EXACT", "EXACT" ]

[]

[ "goslim_pir" ]

[]

[ "GO:1905354" ]

[ "part_of GO:0005622" ]

[ "part_of" ]

[ "GO:0005622" ]

[ "GO:0005622", "GO:1905354" ]

[]

null

false

true

9

GO:0000179

179

rRNA (adenine-N6,N6-)-dimethyltransferase activity

molecular_function

Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor.

[ "ISBN:1555811337", "PMID:10690410" ]

null

[ "18S rRNA dimethylase activity", "dimethyladenosine transferase activity", "S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase activity" ]

[ "EXACT", "EXACT", "EXACT" ]

[ "GO:0043790" ]

[]

[ "Reactome:R-HSA-6790994 \"DIMT1 dimethylates adenosine-1850,1851 of 18S rRNA yielding 6-dimethyladenosine-1850,1851\"", "Reactome:R-HSA-6793066 \"TFB1M dimethylates adenosine-936 and adenosine-937 of 12S rRNA yielding 6-dimethyladenosine-936 and 6-dimethyladenosine-937\"" ]

[ "GO:0008170", "GO:0016433" ]

[]

[ "GO:0008170", "GO:0016433" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14459\" xsd:anyURI" ]

null

false

true

1

GO:0000180

180

obsolete cytosolic large ribosomal subunit

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

This term was made obsolete because more specific children exist.

[ "cytosolic large ribosomal subunit" ]

[ "EXACT" ]

[]

[ "GO:0022625" ]

[]

null

true

1

GO:0000181

181

obsolete cytosolic small ribosomal subunit

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:ai" ]

This term was made obsolete because more specific children exist.

[ "cytosolic small ribosomal subunit" ]

[ "EXACT" ]

[]

[ "GO:0022627" ]

[]

null

true

7

GO:0000182

182

rDNA binding

molecular_function

Binding to a DNA sequence encoding a ribosomal RNA.

[ "GOC:mah" ]

null

[ "ribosomal DNA binding" ]

[ "EXACT" ]

[]

[ "GO:1990837" ]

[]

[ "GO:1990837" ]

[]

null

false

true

2

GO:0000183

183

rDNA heterochromatin formation

biological_process

The formation of heterochromatin at ribosomal DNA, characterized by the modified histone H3K9me3.

[ "PMID:10219245" ]

null

[ "chromatin silencing at rDNA", "chromatin silencing at ribosomal DNA", "heterochromatic silencing at rDNA", "rDNA chromatin silencing", "rDNA heterochromatin assembly" ]

[ "RELATED", "BROAD", "BROAD", "BROAD", "EXACT" ]

[]

[ "Reactome:R-HSA-427359 \"SIRT1 negatively regulates rRNA expression\"", "Reactome:R-HSA-427413 \"NoRC negatively regulates rRNA expression\"" ]

[ "GO:0140718" ]

[ "part_of GO:1990700" ]

[ "part_of" ]

[ "GO:1990700" ]

[ "GO:0140718", "GO:1990700" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19238\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23553\" xsd:anyURI" ]

null

false

true

6

GO:0000184

184

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

biological_process

The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.

[ "GOC:krc", "GOC:ma", "PMID:10025395" ]

null

[ "mRNA breakdown, nonsense-mediated decay", "mRNA catabolic process, nonsense-mediated", "mRNA catabolism, nonsense-mediated", "mRNA degradation, nonsense-mediated decay", "nonsense-mediated mRNA decay", "nuclear mRNA catabolic process, nonsense-mediated decay" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "Reactome:R-HSA-927802 \"Nonsense-Mediated Decay (NMD)\"", "Wikipedia:Nonsense-mediated_decay", "Wikipedia:Nonsense-mediated_mRNA_decay" ]

[ "GO:0000956" ]

[]

[ "GO:0000956" ]

[]

null

false

true

2

GO:0000185

185

obsolete activation of MAPKKK activity

biological_process

OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK).

[ "PMID:9561267" ]

This term was obsoleted because it represents a molecular function.

[ "activation of MAP kinase kinase kinase", "activation of MAP3K activity", "activation of MAPKKK activity during sporulation", "positive regulation of MAP kinase kinase kinase activity", "positive regulation of MAPKKK activity" ]

[ "EXACT", "EXACT", "NARROW", "BROAD", "BROAD" ]

[]

[ "GO:0000165", "GO:0043539" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21307\" xsd:anyURI" ]

null

true

1

GO:0000186

186

obsolete activation of MAPKK activity

biological_process

OBSOLETE. The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK).

[ "PMID:9561267" ]

This term was obsoleted because it represents a molecular function.

[ "activation of MAP kinase kinase activity", "activation of MAP/ERK kinase kinase", "activation of MAP2K activity", "activation of MAPKK activity during sporulation", "positive regulation of MAPKK activity" ]

[ "EXACT", "EXACT", "EXACT", "NARROW", "BROAD" ]

[]

[ "GO:0000165", "GO:0043539" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21307\" xsd:anyURI" ]

null

true

1

GO:0000187

187

obsolete activation of MAPK activity

biological_process

OBSOLETE. The initiation of the activity of the inactive enzyme MAP kinase (MAPK).

[ "PMID:9561267" ]

This term was obsoleted because it represents a molecular function.

[ "activation of MAP kinase", "activation of MAPK activity during sporulation", "MAPK activation" ]

[ "EXACT", "NARROW", "EXACT" ]

[]

[ "GO:0000165", "GO:0043539" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21307\" xsd:anyURI" ]

null

true

4

GO:0000188

188

obsolete inactivation of MAPK activity

biological_process

OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase.

[ "PMID:9561267" ]

This term was obsoleted because it represents a molecular function.

[ "inactivation of MAPK during sporulation", "termination of MAPK activity" ]

[ "NARROW", "EXACT" ]

[]

[ "GO:0000165", "GO:0043539" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21308\" xsd:anyURI" ]

null

true

3

GO:0000189

189

obsolete MAPK import into nucleus

biological_process

OBSOLETE. The directed movement of a MAP kinase to the nucleus upon activation.

[ "PMID:9561267" ]

The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.

[ "nuclear translocation of MAPK" ]

[ "NARROW" ]

[]

[ "GO:0006606" ]

[]

null

true

4

GO:0000190

190

obsolete MAPKKK cascade (pseudohyphal growth)

biological_process

OBSOLETE. MAPKKK cascade involved in transduction of signal promoting pseudohyphal or invasive growth.

[ "PMID:9561267" ]

This term was made obsolete because it is a gene product specific term.

[ "MAPKKK cascade (pseudohyphal growth)" ]

[ "EXACT" ]

[]

null

true

9

GO:0000191

191

obsolete activation of MAPKKK (pseudohyphal growth)

biological_process

OBSOLETE. Upregulation of MAPKKK activity in the context of regulating pseudohyphal or invasive growth.

[ "PMID:9561267" ]

This term was made obsolete because it is a gene product specific term.

[ "activation of MAPKKK (pseudohyphal growth)" ]

[ "EXACT" ]

[]

null

true

7

GO:0000192

192

obsolete activation of MAPKK (pseudohyphal growth)

biological_process

OBSOLETE. Upregulation of a MAP kinase kinase in the context of regulating pseudohyphal or invasive growth.

[ "PMID:9561267" ]

This term was made obsolete because it is a gene product specific term.

[ "activation of MAPKK (pseudohyphal growth)" ]

[ "EXACT" ]

[]

null

true

3

GO:0000193

193

obsolete activation of MAPK (pseudohyphal growth)

biological_process

OBSOLETE. Upregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth.

[ "PMID:9561267" ]

This term was made obsolete because it is a gene product specific term.

[ "activation of MAPK (pseudohyphal growth)" ]

[ "EXACT" ]

[]

null

true

5

GO:0000194

194

obsolete inactivation of MAPK (pseudohyphal growth)

biological_process

OBSOLETE. Downregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth.

[ "PMID:9561267" ]

This term was made obsolete because it is a gene product specific term.

[ "inactivation of MAPK (pseudohyphal growth)" ]

[ "EXACT" ]

[]

null

true

8

GO:0000195

195

obsolete nuclear translocation of MAPK (pseudohyphal growth)

biological_process

OBSOLETE. Movement of a MAP kinase to the nucleus in the context of regulating pseudohyphal or invasive growth.

[ "PMID:9561267" ]

This term was made obsolete because it is a gene product specific term.

[ "nuclear translocation of MAPK (pseudohyphal growth)" ]

[ "EXACT" ]

[]

null

true

8

GO:0000196

196

cell integrity MAPK cascade

biological_process

A MAPK cascade that specifically ensures the maintenance and regulation of cellular structure in response to external signals, including plasma membrane stretching or cell wall alteration, to coordinate cellular responses such as growth, differentiation, and stress adaptation, thereby preserving cell integrity. Contain...

[ "GOC:vw" ]

null

[ "cell integrity MAPK pathway", "cell wall integrity MAPK cascade", "CWI pathway", "Mpk1 cascade", "Pmk1 MAPK cell integrity signaling", "Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway", "PMK1-MAPK signal transduction pathway", "Slt2 cascade" ]

[ "EXACT", "NARROW", "RELATED", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:0051403" ]

[]

[ "GO:0051403" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26610\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28384\" xsd:anyURI" ]

null

false

true

7

GO:0000197

197

obsolete activation of MAPKKK activity involved in cell wall organization or biogenesis

biological_process

OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of cell wall organization or biogenesis.

[ "PMID:9561267" ]

This term was obsoleted because it represents a GO-CAM model.

[ "activation of MAP kinase kinase kinase activity during cell wall biogenesis", "activation of MAPKKK activity involved in cell wall biogenesis", "activation of MAPKKK activity involved in cell wall integrity", "cell wall biogenesis, activation of MAP kinase kinase kinase activity", "cell wall biogenesis, ac...

[ "EXACT", "RELATED", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0000165", "GO:0043539" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20242\" xsd:anyURI" ]

null

true

2

GO:0000198

198

obsolete activation of MAPKK activity involved in cell wall organization or biogenesis

biological_process

OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of cell wall organization or biogenesis.

[ "PMID:9561267" ]

This term was obsoleted because it represents a GO-CAM model.

[ "activation of MAP kinase kinase activity during cell wall biogenesis", "activation of MAPKK activity involved in cell wall biogenesis", "activation of MAPKK activity involved in cell wall integrity", "cell wall biogenesis, activation of MAP kinase kinase activity", "cell wall biogenesis, activation of MAPK...

[ "EXACT", "RELATED", "EXACT", "EXACT", "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20242\" xsd:anyURI" ]

null

true

3

GO:0000199

199

obsolete activation of MAPK activity involved in cell wall organization or biogenesis

biological_process

OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells.

[ "PMID:9561267" ]

This term was obsoleted because it represents a GO-CAM model.

[ "activation of MAPK activity involved in cell wall biogenesis", "activation of MAPK activity involved in cell wall integrity", "cell wall biogenesis, activation of MAPK activity" ]

[ "NARROW", "EXACT", "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20242\" xsd:anyURI" ]

null

true

9

GO:0000200

200

obsolete inactivation of MAPK activity involved in cell wall organization or biogenesis

biological_process

OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase in the context of cell wall organization or biogenesis.

[ "PMID:9561267" ]

This term was obsoleted because it represents a GO-CAM model.

[ "cell wall biogenesis, inactivation of MAPK activity", "cell wall biogenesis, termination of MAPK activity", "inactivation of MAPK activity involved in cell wall integrity", "inactivation of MAPK activity involved in cell wall organization or biogenesis", "termination of MAPK activity during cell wall bioge...

[ "EXACT", "EXACT", "EXACT", "RELATED", "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20242\" xsd:anyURI" ]

null

true

4

GO:0000201

201

obsolete MAPK import into nucleus involved in cell wall organization or biogenesis

biological_process

OBSOLETE. The directed movement of a MAP kinase to the nucleus that occurs in the context of cell wall organization or biogenesis.

[ "PMID:9561267" ]

The reason for obsoletion is that this term represents a GO-CAM model.

[ "cell wall biogenesis, MAPK import into nucleus", "cell wall biogenesis, nuclear translocation of MAPK", "MAPK import into nucleus involved in cell wall biogenesis", "MAPK import into nucleus involved in cell wall integrity", "nuclear translocation of MAPK involved in cell wall biogenesis", "nuclear trans...

[ "EXACT", "NARROW", "NARROW", "EXACT", "NARROW", "NARROW" ]

[]

[ "GO:0006606" ]

[]

null

true

9

GO:0000202

202

obsolete MAPKKK cascade during sporulation (sensu Saccharomyces)

biological_process

OBSOLETE. MAPKKK cascade involved in transduction of signal promoting sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).

[ "PMID:9561267" ]

This term was made obsolete because it is a gene product specific term.

[ "MAPKKK cascade during sporulation (sensu Saccharomyces)" ]

[ "EXACT" ]

[]

null

true

7

GO:0000203

203

obsolete activation of MAPKKK during sporulation (sensu Saccharomyces)

biological_process

OBSOLETE. Upregulation of MAPKKK activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).

[ "PMID:9561267" ]

This term was made obsolete because it is a gene product specific term.

[ "activation of MAPKKK during sporulation (sensu Saccharomyces)" ]

[ "EXACT" ]

[]

null

true

1

GO:0000204

204

obsolete activation of MAPKK during sporulation (sensu Saccharomyces)

biological_process

OBSOLETE. Upregulation of a MAP kinase kinase in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).

[ "PMID:9561267" ]

This term was made obsolete because it is a gene product specific term.

[ "activation of MAPKK during sporulation (sensu Saccharomyces)" ]

[ "EXACT" ]

[]

null

true

5

GO:0000205

205

obsolete activation of MAPK during sporulation (sensu Saccharomyces)

biological_process

OBSOLETE. Upregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).

[ "PMID:9561267" ]

This term was made obsolete because it is a gene product specific term.

[ "activation of MAPK during sporulation (sensu Saccharomyces)" ]

[ "EXACT" ]

[]

null

true

2

GO:0000206

206

obsolete inactivation of MAPK during sporulation (sensu Saccharomyces)

biological_process

OBSOLETE. Downregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).

[ "PMID:9561267" ]

This term was made obsolete because it is a gene product specific term.

[ "inactivation of MAPK during sporulation (sensu Saccharomyces)" ]

[ "EXACT" ]

[]

null

true

1

GO:0000208

208

obsolete MAPK import into nucleus involved in osmosensory signaling pathway

biological_process

OBSOLETE. The directed movement of a MAP kinase to the nucleus during osmolarity sensing.

[ "PMID:9561267" ]

The reason for obsoletion is that this term represents a GO-CAM model.

[ "MAPK import into nucleus during osmolarity sensing", "MAPK import into nucleus involved in osmosensory signalling pathway", "nuclear translocation of MAPK during osmolarity sensing", "nuclear translocation of MAPK involved in osmosensory signaling pathway", "nuclear translocation of MAPK involved in osmose...

[ "EXACT", "EXACT", "EXACT", "NARROW", "NARROW", "EXACT", "NARROW" ]

[]

[ "GO:0006606" ]

[]

null

true

9

GO:0000209

209

protein polyubiquitination

biological_process

Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.

[ "PMID:26906419" ]

null

[ "polyubiquitin", "protein polyubiquitinylation", "protein polyubiquitylation" ]

[ "RELATED", "EXACT", "EXACT" ]

[]

[ "Reactome:R-HSA-983168 \"Antigen processing: Ubiquitination & Proteasome degradation\"" ]

[ "GO:0016567" ]

[]

[ "GO:0016567" ]

[]

null

false

true

9

GO:0000210

210

NAD+ diphosphatase activity

molecular_function

Catalysis of the reaction: NAD+ + H2O = AMP + NMN.

[ "RHEA:11800" ]

null

[ "NAD diphosphatase activity", "NAD pyrophosphatase activity", "NAD(+) pyrophosphatase activity", "NAD+ phosphohydrolase activity", "NAD+ pyrophosphatase activity", "NADP pyrophosphatase activity", "nicotinamide adenine dinucleotide pyrophosphatase activity" ]

[ "BROAD", "BROAD", "EXACT", "EXACT", "EXACT", "RELATED", "RELATED" ]

[]

[ "MetaCyc:NADPYROPHOSPHAT-RXN", "RHEA:11800" ]

[ "GO:0004551" ]

[]

[ "GO:0004551" ]

[]

[ "skos:broadMatch EC:3.6.1.22", "skos:exactMatch RHEA:11800", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19775\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

4

GO:0000211

211

obsolete protein degradation tagging activity

molecular_function

OBSOLETE. Covalent addition of polyubiquitin to another protein, targeting the tagged protein for destruction.

[ "GOC:cl", "ISBN:0815316194" ]

This term was made obsolete because it represents a biological process and a molecular function.

[ "protein degradation tagging activity" ]

[ "EXACT" ]

[]

[ "GO:0005515", "GO:0019941" ]

[]

null

true

8

GO:0000212

212

meiotic spindle organization

biological_process

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle.

[ "GOC:curators", "GOC:mah" ]

null

[ "meiotic spindle organisation", "meiotic spindle organization and biogenesis", "meiotic spindle stabilization", "spindle organization during meiosis" ]

[ "EXACT", "RELATED", "RELATED", "EXACT" ]

[ "GO:0043147" ]

[]

[ "GO:0007051", "GO:1903046" ]

[]

[ "GO:0007051", "GO:1903046" ]

[ "GO:0007051", "part_of GO:0051321" ]

[]

null

false

true

7

GO:0000213

213

tRNA-intron lyase activity

molecular_function

Catalysis of the reaction: pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.

[ "EC:4.6.1.16" ]

null

[ "tRNA splicing endonuclease activity", "tRNA-intron endonuclease activity", "tRNA-intron endoribonuclease activity" ]

[ "RELATED", "EXACT", "EXACT" ]

[]

[ "EC:4.6.1.16", "MetaCyc:3.1.27.9-RXN" ]

[ "GO:0004521", "GO:0004549", "GO:0016849" ]

[]

[ "GO:0004521", "GO:0004549", "GO:0016849" ]

[]

[ "skos:exactMatch EC:4.6.1.16", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24408\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

9

GO:0000214

214

tRNA-intron endonuclease complex

cellular_component

A protein complex that catalyzes the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.

[ "PMID:22391451" ]

null

[ "SEN complex", "tRNA splicing endonuclease complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0140513", "GO:1902555" ]

[]

[ "GO:0140513", "GO:1902555" ]

[]

null

false

true

8

GO:0000215

215

tRNA 2'-phosphotransferase activity

molecular_function

Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate.

[ "EC:2.7.1.160", "PMID:9148937" ]

null

[ "2'-phospho-[ligated tRNA]:NAD+ phosphotransferase activity", "2'-phospho-tRNA:NAD+ phosphotransferase activity", "2'-phosphotransferase activity", "Tpt1", "Tpt1p", "yeast 2'-phosphotransferase activity" ]

[ "RELATED", "RELATED", "BROAD", "RELATED", "RELATED", "NARROW" ]

[ "GO:0008665" ]

[ "goslim_chembl" ]

[ "EC:2.7.1.160", "MetaCyc:2.7.1.160-RXN", "RHEA:23324" ]

[ "GO:0016773", "GO:0140101" ]

[]

[ "GO:0016773", "GO:0140101" ]

[]

[ "skos:exactMatch EC:2.7.1.160", "skos:exactMatch RHEA:23324", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

8

GO:0000216

216

obsolete M/G1 transition of mitotic cell cycle

biological_process

OBSOLETE. Progression from M phase to G1 phase of the mitotic cell cycle.

[ "GOC:mah", "GOC:mtg_cell_cycle" ]

This term was made obsolete because it does not refer to a real biological process.

[ "M/G1 transition of mitotic cell cycle" ]

[ "EXACT" ]

[]

null

true

6

GO:0000217

217

DNA secondary structure binding

molecular_function

Binding to a DNA secondary structure element such as a four-way junction, a bubble, a loop, Y-form DNA, or a double-strand/single-strand junction.

[ "GOC:krc" ]

null

[]

[ "GO:0003677" ]

[]

[ "GO:0003677" ]

[]

null

false

true

5

GO:0000219

219

obsolete vacuolar hydrogen-transporting ATPase

cellular_component

OBSOLETE. (Was not defined before being made obsolete).

[ "GOC:curators" ]

This term was made obsolete because more specific terms were created.

[ "V-ATPase", "vacuolar hydrogen-transporting ATPase" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0016469" ]

[]

null

true

3

GO:0000220

220

vacuolar proton-transporting V-type ATPase, V0 domain

cellular_component

The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.

[ "GOC:mah", "PMID:16449553" ]

Note that this domain often consists of five subunits, although in some mammalian tissues it may have an additional subunit.

[ "vacuolar hydrogen ion-transporting ATPase V0 domain" ]

[ "EXACT" ]

[]

[ "GO:0033179" ]

[ "part_of GO:0016471" ]

[ "part_of" ]

[ "GO:0016471" ]

[ "GO:0016471", "GO:0033179" ]

[ "GO:0033179", "part_of GO:0005774" ]

[]

null

false

true

9

GO:0000221

221

vacuolar proton-transporting V-type ATPase, V1 domain

cellular_component

The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.

[ "GOC:mah", "PMID:16449553" ]

Note that this domain generally consists of eight subunits.

[ "vacuolar hydrogen ion-transporting ATPase V1 domain" ]

[ "EXACT" ]

[]

[ "GO:0033180" ]

[ "part_of GO:0016471" ]

[ "part_of" ]

[ "GO:0016471" ]

[ "GO:0016471", "GO:0033180" ]

[ "GO:0033180", "part_of GO:0005773" ]

[]

null

false

true

3

GO:0000222

222

plasma membrane proton-transporting V-type ATPase, V0 domain

cellular_component

The V0 domain of a proton-transporting V-type ATPase found in the plasma membrane.

[ "GOC:mah" ]

null

[ "plasma membrane hydrogen ion-transporting ATPase V0 domain" ]

[ "EXACT" ]

[]

[ "GO:0033179", "GO:0098797" ]

[ "part_of GO:0033181" ]

[ "part_of" ]

[ "GO:0033181" ]

[ "GO:0033179", "GO:0033181", "GO:0098797" ]

[ "GO:0033179", "part_of GO:0005886" ]

[]

null

false

true

1

GO:0000223

223

plasma membrane proton-transporting V-type ATPase, V1 domain

cellular_component

The V1 domain of a proton-transporting V-type ATPase found in the plasma membrane.

[ "GOC:mah" ]

null

[ "plasma membrane hydrogen ion-transporting ATPase V1 domain" ]

[ "EXACT" ]

[]

[ "GO:0033180", "GO:0098797" ]

[ "part_of GO:0033181" ]

[ "part_of" ]

[ "GO:0033181" ]

[ "GO:0033180", "GO:0033181", "GO:0098797" ]

[ "GO:0033180", "part_of GO:0005886" ]

[]

null

false

true

1

GO:0000224

224

peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity

molecular_function

Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-ac...

[ "EC:3.5.1.52" ]

null

[ "glycopeptidase activity", "glycopeptide N-glycosidase activity", "jack-bean glycopeptidase", "N-glycanase activity", "N-linked-glycopeptide-(N-acetyl-beta-D-glucosaminyl)-L-asparagine amidohydrolase activity", "N-oligosaccharide glycopeptidase activity", "peptide:N-glycanase", "PNGase", "PNGase A",...

[ "BROAD", "BROAD", "NARROW", "RELATED", "RELATED", "RELATED", "RELATED", "EXACT", "RELATED", "RELATED" ]

[]

[ "EC:3.5.1.52", "MetaCyc:3.5.1.52-RXN", "Reactome:R-HSA-8850594 \"Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins\"" ]

[ "GO:0016811" ]

[]

[ "GO:0016811" ]

[]

[ "skos:exactMatch EC:3.5.1.52", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

6

GO:0000225

225

N-acetylglucosaminylphosphatidylinositol deacetylase activity

molecular_function

Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane.

[ "EC:3.5.1.89" ]

null

[ "6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity", "acetylglucosaminylphosphatidylinositol deacetylase activity", "GlcNAc-PI de-N-acetylase activity", "GlcNAc-PI deacetylase activity", "N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity", "N-acet...

[ "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED" ]

[]

[ "EC:3.5.1.89", "MetaCyc:3.1.1.69-RXN", "Reactome:R-HSA-162857 \"N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate\"", "RHEA:11660" ]

[ "GO:0016811", "GO:0019213" ]

[]

[ "GO:0016811", "GO:0019213" ]

[]

[ "skos:exactMatch EC:3.5.1.89", "skos:exactMatch RHEA:11660", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

8

GO:0000226

226

microtubule cytoskeleton organization

biological_process

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.

[ "GOC:mah" ]

null

[ "microtubule cytoskeleton organisation", "microtubule cytoskeleton organization and biogenesis" ]

[ "EXACT", "RELATED" ]

[]

[ "goslim_pombe" ]

[]

[ "GO:0007010", "GO:0007017" ]

[]

[ "GO:0007010", "GO:0007017" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23114\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23195\" xsd:anyURI" ]

null

false

true

5

GO:0000227

227

obsolete oxaloacetate secondary active transmembrane transporter activity

molecular_function

OBSOLETE. Enables the transfer of oxaloacetate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active t...

[ "GOC:mtg_transport" ]

This term was obsoleted because it does not define a specific transport mechanism.

[ "oxaloacetate carrier activity" ]

[ "RELATED" ]

[]

[ "GO:0015131" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27771\" xsd:anyURI" ]

null

true

1

GO:0000229

229

obsolete cytoplasmic chromosome

cellular_component

OBSOLETE. A chromosome found in the cytoplasm.

[ "GOC:mah" ]

This term was obsoleted because it is an unnecessary grouping class.

[ "cytoplasmic interphase chromosome" ]

[ "NARROW" ]

[]

[ "GO:0005694" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22177\" xsd:anyURI" ]

null

true

4

GO:0000230

230

obsolete nuclear mitotic chromosome

cellular_component

OBSOLETE. A chromosome found in the nucleus during mitosis.

[ "GOC:mah" ]

This term was made obsolete because it is based on a temporal division of the cell cycle.

[ "nuclear mitotic chromosome" ]

[ "EXACT" ]

[]

[ "GO:0000794" ]

[]

null

true

3

GO:0000231

231

obsolete cytoplasmic mitotic chromosome

cellular_component

OBSOLETE. A chromosome found in the cytoplasm during mitosis.

[ "GOC:mah" ]

This term was made obsolete because it is based on a temporal division of the cell cycle.

[ "cytoplasmic mitotic chromosome" ]

[ "EXACT" ]

[]

[ "GO:0000793" ]

[]

null

true

5

GO:0000232

232

obsolete nuclear interphase chromosome

cellular_component

OBSOLETE. A chromosome found in the nucleus during interphase.

[ "GOC:mah" ]

This term was made obsolete because it is based on a temporal division of the cell cycle.

[ "nuclear interphase chromosome" ]

[ "EXACT" ]

[]

[ "GO:0000228" ]

[]

null

true

7

GO:0000233

233

obsolete cytoplasmic interphase chromosome

cellular_component

OBSOLETE. A chromosome found in the cytoplasm during interphase.

[ "GOC:mah" ]

This term was made obsolete because it is based on a temporal division of the cell cycle.

[ "cytoplasmic interphase chromosome" ]

[ "EXACT" ]

[]

[ "GO:0005694" ]

[]

null

true

5

GO:0000234

234

phosphoethanolamine N-methyltransferase activity

molecular_function

Catalysis of the reaction: S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-homocysteine + N-methylethanolamine phosphate.

[ "EC:2.1.1.103" ]

null

[ "phosphoethanolamine methyltransferase activity", "S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase activity" ]

[ "RELATED", "RELATED" ]

[]

[ "EC:2.1.1.103", "KEGG_REACTION:R02037", "KEGG_REACTION:R06868", "MetaCyc:2.1.1.103-RXN", "MetaCyc:RXN-5642", "MetaCyc:RXN-5643", "RHEA:20365", "RHEA:25321", "RHEA:25325" ]

[ "GO:0008170", "GO:0008757" ]

[]

[ "GO:0008170", "GO:0008757" ]

[]

[ "skos:exactMatch EC:2.1.1.103", "skos:narrowMatch MetaCyc:2.1.1.103-RXN", "skos:narrowMatch MetaCyc:RXN-5642", "skos:narrowMatch MetaCyc:RXN-5643", "skos:narrowMatch RHEA:20365", "skos:narrowMatch RHEA:25321", "skos:narrowMatch RHEA:25325", "term_tracker_item \"https://github.com/geneontology/go-ontol...

null

false

true

5

GO:0000235

235

astral microtubule

cellular_component

Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.

[ "ISBN:0815316194" ]

null

[]

[ "GO:0005876", "GO:0005881" ]

[ "part_of GO:0005818" ]

[ "part_of" ]

[ "GO:0005818" ]

[ "GO:0005818", "GO:0005876", "GO:0005881" ]

[ "GO:0005876", "part_of GO:0005818" ]

[]

null

false

true

1

GO:0000236

236

mitotic prometaphase

biological_process

The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtu...

[ "GOC:mtg_cell_cycle" ]

Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phas...

[]

[ "gocheck_do_not_annotate" ]

[ "Reactome:R-HSA-68877 \"Mitotic Prometaphase\"" ]

[ "GO:0000087" ]

[]

[ "GO:0000087" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24374\" xsd:anyURI" ]

null

false

true

2

GO:0000237

237

leptotene

biological_process

The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible.

[ "GOC:mtg_cell_cycle" ]

Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phas...

[]

[ "gocheck_do_not_annotate" ]

[ "Wikipedia:Leptotene", "Wikipedia:Meiosis#Leptotene" ]

[ "GO:0098764" ]

[ "part_of GO:0007128" ]

[ "part_of" ]

[ "GO:0007128" ]

[ "GO:0007128", "GO:0098764" ]

[]

null

false

true

1

GO:0000238

238

zygotene

biological_process

The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur.

[ "GOC:mtg_cell_cycle" ]

Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phas...

[]

[ "gocheck_do_not_annotate" ]

[ "Wikipedia:Meiosis#Zygotene", "Wikipedia:Zygotene" ]

[ "GO:0098764" ]

[ "part_of GO:0007128" ]

[ "part_of" ]

[ "GO:0007128" ]

[ "GO:0007128", "GO:0098764" ]

[]

null

false

true

7

GO:0000239

239

pachytene

biological_process

The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome.

[ "GOC:mtg_cell_cycle" ]

Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phas...

[]

[ "gocheck_do_not_annotate" ]

[ "Wikipedia:Meiosis#Pachytene", "Wikipedia:Pachytene" ]

[ "GO:0098764" ]

[ "part_of GO:0007128" ]

[ "part_of" ]

[ "GO:0007128" ]

[ "GO:0007128", "GO:0098764" ]

[]

null

false

true

8

GO:0000240

240

diplotene

biological_process

The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.

[ "GOC:mtg_cell_cycle" ]

Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phas...

[]

[ "gocheck_do_not_annotate" ]

[ "Wikipedia:Diplotene", "Wikipedia:Meiosis#Diplotene" ]

[ "GO:0098764" ]

[ "part_of GO:0007128" ]

[ "part_of" ]

[ "GO:0007128" ]

[ "GO:0007128", "GO:0098764" ]

[]

null

false

true

3

GO:0000241

241

diakinesis

biological_process

The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred.

[ "GOC:mtg_cell_cycle" ]

Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phas...

[]

[ "gocheck_do_not_annotate" ]

[ "Wikipedia:Diakinesis", "Wikipedia:Meiosis#Diakinesis" ]

[ "GO:0098764" ]

[ "part_of GO:0007128" ]

[ "part_of" ]

[ "GO:0007128" ]

[ "GO:0007128", "GO:0098764" ]

[]

null

false

true

1

GO:0000242

242

pericentriolar material

cellular_component

A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome.

[ "GOC:clt", "ISBN:0815316194" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0005813" ]

[ "part_of" ]

[ "GO:0005813" ]

[ "GO:0005813", "GO:0110165" ]

[]

null

false

true

6

GO:0000243

243

commitment complex

cellular_component

A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript.

[ "GOC:krc", "ISBN:0879695897", "PMID:9150140" ]

null

[ "mammalian spliceosomal complex E", "mammalian spliceosomal E complex", "yeast spliceosomal complex CC" ]

[ "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:0005684" ]

[ "has_part GO:0005685" ]

[ "has_part" ]

[ "GO:0005685" ]

[ "GO:0005684", "GO:0005685" ]

[]

null

false

true

2

GO:0000244

244

spliceosomal tri-snRNP complex assembly

biological_process

The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent assoc...

[ "ISBN:0879695897", "PMID:9452384" ]

null

[ "assembly of spliceosomal tri-snRNP", "assembly of spliceosomal tri-snRNP U4/U6.U5", "assembly of spliceosomal tri-snRNP U4atac/U6atac.U5", "snRNP recycling", "spliceosomal tri-snRNP assembly", "spliceosomal tri-snRNP U4/U6.U5 assembly", "spliceosomal tri-snRNP U4atac/U6atac.U5 assembly" ]

[ "EXACT", "NARROW", "NARROW", "BROAD", "EXACT", "NARROW", "NARROW" ]

[ "GO:0000351", "GO:0000355" ]

[]

[ "GO:0000387" ]

[]

[ "GO:0000387" ]

[]

null

false

true

6

GO:0000245

245

spliceosomal complex assembly

biological_process

The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions.

[ "PMID:9476892" ]

null

[ "spliceosome assembly" ]

[ "BROAD" ]

[]

[ "GO:0022618" ]

[ "part_of GO:0000398" ]

[ "part_of" ]

[ "GO:0000398" ]

[ "GO:0000398", "GO:0022618" ]

[]

null

false

true

4

GO:0000246

246

Delta24(24-1) sterol reductase activity

molecular_function

Catalysis of the reaction: ergosterol + NADP+ = ergosta-5,7,22,24(24(1))-tetraen-3beta-ol + H+ + NADPH.

[ "EC:1.3.1.71", "RHEA:18501" ]

null

[ "C-24(28) sterol reductase activity", "D24(24-1)-sterol reductase activity", "delta24(241)-sterol reductase activity", "ergosterol:NADP+ delta24(241)-oxidoreductase activity", "sterol Delta(24(28))-methylene reductase activity", "sterol Delta(24(28))-reductase activity", "sterol delta-24(28) methylene r...

[ "RELATED", "EXACT", "RELATED", "RELATED", "RELATED", "RELATED", "EXACT", "EXACT", "RELATED", "RELATED" ]

[]

[ "EC:1.3.1.71", "KEGG_REACTION:R05641", "MetaCyc:1.3.1.71-RXN", "RHEA:18501" ]

[ "GO:0016628" ]

[]

[ "GO:0016628" ]

[]

[ "skos:exactMatch EC:1.3.1.71", "skos:exactMatch RHEA:18501", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

4

GO:0000247

247

C-8 sterol isomerase activity

molecular_function

Catalysis of the reaction: fecosterol = episterol.

[ "PMID:8988026", "RHEA:33435" ]

null

[ "delta-8-delta-7 sterol isomerase activity" ]

[ "EXACT" ]

[]

[ "MetaCyc:RXN3O-203", "RHEA:33435" ]

[ "GO:0016863" ]

[]

[ "GO:0016863" ]

[]

[ "skos:exactMatch MetaCyc:RXN3O-203", "skos:exactMatch RHEA:33435", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28324\" xsd:anyURI" ]

null

false

true

5

GO:0000248

248

C-5 sterol desaturase activity

molecular_function

Catalysis of the reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+.

[ "GOC:curators" ]

null

[ "sterol-C5-desaturase activity" ]

[ "EXACT" ]

[]

[ "Reactome:R-HSA-195664 \"Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol\"", "Reactome:R-HSA-6807053 \"SC5D desaturates LTHSOL to 7-dehydroCHOL\"" ]

[ "GO:0070704" ]

[]

[ "GO:0070704" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27381\" xsd:anyURI" ]

null

false

true

6

GO:0000249

249

C-22 sterol desaturase (NADPH) activity

molecular_function

Catalysis of the reaction: 5-dehydroepisterol + H+ + NADPH + O2 = ergosta-5,7,22,24(28)-tetraen-3beta-ol + 2 H2O + NADP+. This reaction is the introduction of a double bond between the C-22 and C-23 carbons of certain sterols. Also converts sitosterol and 24-epi-campesterol to stigmasterol and brassicasterol, respectiv...

[ "EC:1.14.19.41" ]

null

[]

[ "EC:1.14.19.41", "MetaCyc:RXN3O-227", "RHEA:33467", "RHEA:46576" ]

[ "GO:0070704" ]

[]

[ "GO:0070704" ]

[]

[ "skos:exactMatch EC:1.14.19.41", "skos:exactMatch MetaCyc:RXN3O-227", "skos:narrowMatch RHEA:33467", "skos:narrowMatch RHEA:46576", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27381\" xsd:anyURI" ]

null

false

true

7

GO:0000250

250

lanosterol synthase activity

molecular_function

Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus.

[ "EC:5.4.99.7", "RHEA:14621" ]

null

[ "(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming)", "2,3-epoxysqualene lanosterol cyclase activity", "2,3-epoxysqualene--lanosterol cyclase activity", "2,3-epoxysqualene-lanosterol cyclase activity", "2,3-oxidosqualene sterol cyclase activity", "2,3-oxidosqualene-lanosterol cyclase activity", ...

[ "RELATED", "RELATED", "RELATED", "EXACT", "BROAD", "RELATED", "RELATED", "EXACT", "RELATED", "EXACT", "EXACT", "RELATED", "BROAD", "RELATED" ]

[]

[ "EC:5.4.99.7", "KEGG_REACTION:R03199", "MetaCyc:LANOSTEROL-SYNTHASE-RXN", "Reactome:R-HSA-191366 \"Squalene 2,3-epoxide cyclizes, forming lanosterol\"", "RHEA:14621" ]

[ "GO:0031559" ]

[]

[ "GO:0031559" ]

[]

[ "skos:exactMatch EC:5.4.99.7", "skos:exactMatch RHEA:14621", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

6