go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0000380
380
alternative mRNA splicing, via spliceosome
biological_process
The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
[ "GOC:krc", "PMID:12110900" ]
Note that this process most commonly occurs in cis, selecting or skipping exons from the same primary transcript, but it has also been observed to occur in trans at low frequency, at least in some mammals.
[ "alternative nuclear mRNA splicing, via spliceosome", "splice site selection" ]
[ "EXACT", "BROAD" ]
[]
[]
[]
[ "GO:0000398" ]
[]
[]
[]
[ "GO:0000398" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0000381
381
regulation of alternative mRNA splicing, via spliceosome
biological_process
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
[ "GOC:krc" ]
null
[ "regulation of alternative nuclear mRNA splicing, via spliceosome", "splice site selection" ]
[ "EXACT", "BROAD" ]
[]
[]
[]
[ "GO:0048024" ]
[ "regulates GO:0000380" ]
[ "regulates" ]
[ "GO:0000380" ]
[ "GO:0000380", "GO:0048024" ]
[ "GO:0065007", "regulates GO:0000380" ]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0000384
384
first spliceosomal transesterification activity
molecular_function
Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the ...
[ "GOC:krc", "ISBN:0879695897", "PMID:19239890" ]
null
[ "lariat formation, 5'-splice site cleavage" ]
[ "RELATED" ]
[]
[]
[ "Reactome:R-HSA-9794542 \"Formation of the Spliceosomal C complex containing intron lariat\"" ]
[ "GO:0140098" ]
[ "part_of GO:0000375" ]
[ "part_of" ]
[ "GO:0000375" ]
[ "GO:0000375", "GO:0140098" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0000386
386
second spliceosomal transesterification activity
molecular_function
Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicin...
[ "GOC:krc", "ISBN:0879695897", "PMID:19239890" ]
null
[ "3'-splice site cleavage, exon ligation", "lariat formation, 5'-splice site cleavage" ]
[ "BROAD", "RELATED" ]
[]
[]
[ "Reactome:R-HSA-9770236 \"Formation of the Spliceosomal P complex and exon ligation\"" ]
[ "GO:0140098" ]
[ "part_of GO:0000375" ]
[ "part_of" ]
[ "GO:0000375" ]
[ "GO:0000375", "GO:0140098" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0000387
387
spliceosomal snRNP assembly
biological_process
The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome.
[ "GOC:krc", "GOC:mah", "ISBN:0879695897" ]
null
[ "spliceosomal snRNP biogenesis" ]
[ "RELATED" ]
[]
[]
[ "Reactome:R-HSA-191859 \"snRNP Assembly\"" ]
[ "GO:0022618" ]
[ "part_of GO:0000398" ]
[ "part_of" ]
[ "GO:0000398" ]
[ "GO:0000398", "GO:0022618" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0000388
388
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
biological_process
Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11).
[ "GOC:krc", "ISBN:0879695897" ]
Note that this step represents formation of the A1 complex (yeast) or the B2 complex (mammalian).
[ "3'-splice site cleavage, exon ligation", "spliceosomal A1 complex biosynthesis", "spliceosomal A1 complex formation", "spliceosomal B2 complex biosynthesis", "spliceosomal B2 complex formation", "U12-type spliceosome conformational change to release U4atac and U11", "U2-type spliceosome conformational ...
[ "BROAD", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW" ]
[ "GO:0000396", "GO:0000397" ]
[]
[]
[ "GO:0022618" ]
[ "part_of GO:0000393" ]
[ "part_of" ]
[ "GO:0000393" ]
[ "GO:0000393", "GO:0022618" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0000389
389
mRNA 3'-splice site recognition
biological_process
Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome.
[ "GOC:krc", "ISBN:0879695897" ]
null
[ "nuclear mRNA 3'-splice site recognition", "U12-type nuclear mRNA 3'-splice site recognition", "U2-type nuclear mRNA 3'-splice site recognition" ]
[ "EXACT", "NARROW", "NARROW" ]
[ "GO:0000382", "GO:0000383" ]
[]
[]
[ "GO:0006376" ]
[]
[]
[]
[ "GO:0006376" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0000390
390
spliceosomal complex disassembly
biological_process
Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure.
[ "GOC:krc", "ISBN:0879695897" ]
null
[ "spliceosome complex disassembly", "spliceosome disassembly", "U12-type spliceosome disassembly", "U2-type spliceosome disassembly" ]
[ "EXACT", "BROAD", "NARROW", "NARROW" ]
[ "GO:0000391", "GO:0000392" ]
[]
[]
[ "GO:0032988" ]
[ "part_of GO:0000398" ]
[ "part_of" ]
[ "GO:0000398" ]
[ "GO:0000398", "GO:0032988" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0000393
393
spliceosomal conformational changes to generate catalytic conformation
biological_process
Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation.
[ "GOC:krc" ]
null
[ "3'-splice site cleavage, exon ligation" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0022618" ]
[ "part_of GO:0000398" ]
[ "part_of" ]
[ "GO:0000398" ]
[ "GO:0000398", "GO:0022618" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0000394
394
RNA splicing, via endonucleolytic cleavage and ligation
biological_process
Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
[ "GOC:krc", "ISBN:0879695897" ]
Note that while typically associated with tRNA splicing, this mechanism of splicing is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.
[ "mRNA splicing" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0008380" ]
[]
[]
[]
[ "GO:0008380" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0000398
398
mRNA splicing, via spliceosome
biological_process
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
[ "GOC:krc", "ISBN:0198506732", "ISBN:0879695897" ]
Note that although the many U12-type introns have the sequence AT-AC at the intron termini, some introns with these terminal sequences are spliced by the U2-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. Note that although the maj...
[ "mRNA splicing", "nuclear mRNA splicing via U12-type spliceosome", "nuclear mRNA splicing via U2-type spliceosome", "nuclear mRNA splicing, via spliceosome", "pre-mRNA splicing", "splicing AT-AC intron", "splicing GT-AG intron" ]
[ "BROAD", "NARROW", "NARROW", "EXACT", "BROAD", "RELATED", "RELATED" ]
[ "GO:0006374", "GO:0006375" ]
[]
[ "Reactome:R-HSA-72163 \"mRNA Splicing - Major Pathway\"", "Reactome:R-HSA-72165 \"mRNA Splicing - Minor Pathway\"" ]
[ "GO:0000377", "GO:0006397" ]
[]
[]
[]
[ "GO:0000377", "GO:0006397" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0000399
399
cellular bud neck septin structure
cellular_component
Any of a series of septin structures that are localized in the bud neck of a budding fungal cell during the cell cycle.
[ "GOC:krc" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005935", "part_of GO:0032153" ]
[ "part_of", "part_of" ]
[ "GO:0005935", "GO:0032153" ]
[ "GO:0005935", "GO:0032153", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0000400
400
four-way junction DNA binding
molecular_function
Binding to a DNA segment containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.
[ "GOC:krc", "ISBN:0815332181", "PMID:15563464" ]
null
[ "forked DNA binding", "Holliday junction binding" ]
[ "BROAD", "EXACT" ]
[]
[]
[]
[ "GO:0000217" ]
[]
[]
[]
[ "GO:0000217" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0000401
401
open form four-way junction DNA binding
molecular_function
Binding to a DNA segment containing the open form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The open form of a four-way junction can be diagrammed...
[ "GOC:krc", "ISBN:0815332181", "PMID:15563464" ]
null
[ "open form Holliday junction binding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0000400" ]
[]
[]
[]
[ "GO:0000400" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0000402
402
crossed form four-way junction DNA binding
molecular_function
Binding to a DNA segment containing the crossed form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The crossed form of a four-way junction cannot be d...
[ "GOC:krc", "ISBN:0815332181", "PMID:15563464" ]
null
[ "crossed form Holliday junction binding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0000400" ]
[]
[]
[]
[ "GO:0000400" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0000403
403
Y-form DNA binding
molecular_function
Binding to a DNA segment shaped like a Y. This shape occurs when DNA contains a region of paired double-stranded DNA on one end and a region of unpaired DNA strands on the opposite end.
[ "GOC:elh", "PMID:16781730" ]
null
[ "forked DNA binding", "splayed Y-form DNA binding" ]
[ "BROAD", "EXACT" ]
[]
[]
[]
[ "GO:0000217" ]
[]
[]
[]
[ "GO:0000217" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0000404
404
heteroduplex DNA loop binding
molecular_function
Binding to a DNA segment containing a loop. A loop occurs when DNA contains a large insertion or deletion that causes a region of unpaired single-stranded DNA to loop out, while the rest of the DNA is in a paired double-stranded configuration.
[ "GOC:elh", "PMID:16781730" ]
null
[ "loop DNA binding" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0000217", "GO:0032135" ]
[]
[]
[]
[ "GO:0000217", "GO:0032135" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0000405
405
bubble DNA binding
molecular_function
Binding to DNA segment that contains a bubble. A bubble occurs when DNA contains a region of unpaired, single-stranded DNA flanked on both sides by regions of paired, double-stranded DNA.
[ "GOC:elh", "GOC:vw", "PMID:16781730" ]
null
[]
[]
[]
[]
[]
[ "GO:0000217" ]
[]
[]
[]
[ "GO:0000217" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0000406
406
double-strand/single-strand DNA junction binding
molecular_function
Binding to a DNA segment that contains double-stranded DNA flanked by a region of single-stranded DNA.
[ "GOC:elh", "PMID:16781730" ]
null
[]
[]
[]
[]
[]
[ "GO:0000217" ]
[]
[]
[]
[ "GO:0000217" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0000407
407
phagophore assembly site
cellular_component
Punctate structures proximal to the endoplasmic reticulum which are the sites where the Atg machinery assembles upon autophagy induction.
[ "GOC:elh", "PMID:11689437", "PMID:12048214", "PMID:12554655" ]
null
[ "PAS", "perivacuolar space", "pre-autophagosomal structure" ]
[ "EXACT", "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005737" ]
[ "part_of" ]
[ "GO:0005737" ]
[ "GO:0005737", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0000408
408
EKC/KEOPS complex
cellular_component
A protein complex involved in t6A tRNA modification. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p.
[ "GOC:elh", "GOC:vw", "PMID:16564010", "PMID:16874308", "PMID:21183954", "PMID:23945934" ]
Originally proposed to be involved in transcription as well as promoting telomere uncapping and telomere elongation.
[ "endopeptidase-like kinase chromatin-associated protein complex", "KEOPS/EKC complex", "kinase, putative endopeptidase and other proteins of small size protein complex", "TCTC", "threonyl-carbamoly transferase complex" ]
[ "EXACT", "EXACT", "EXACT", "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:1990234" ]
[]
[]
[]
[ "GO:1990234" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27727\" xsd:anyURI" ]
null
null
false
true
3
GO:0000409
409
regulation of transcription by galactose
biological_process
Any process involving galactose that modulates the frequency, rate or extent or transcription.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0006355" ]
[]
[]
[]
[ "GO:0006355" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0000410
410
carbon catabolite repression of transcription by galactose
biological_process
A transcription regulation process in which the presence of galactose that leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites ...
[ "GOC:mah" ]
null
[ "down regulation of transcription by galactose", "down-regulation of transcription by galactose", "downregulation of transcription by galactose", "inhibition of transcription by galactose" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0000409", "GO:0045013" ]
[]
[]
[]
[ "GO:0000409", "GO:0045013" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0000411
411
positive regulation of transcription by galactose
biological_process
Any process involving galactose that activates or increases the rate of transcription.
[ "GOC:curators" ]
null
[ "activation of transcription by galactose", "stimulation of transcription by galactose", "up regulation of transcription by galactose", "up-regulation of transcription by galactose", "upregulation of transcription by galactose" ]
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0000409", "GO:0045991" ]
[]
[]
[]
[ "GO:0000409", "GO:0045991" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0000412
412
obsolete histone peptidyl-prolyl isomerization
biological_process
OBSOLETE. The modification of a histone by cis-trans isomerization of a proline residue.
[ "GOC:krc" ]
This term was obsoleted because it represents a molecular function.
[ "histone proline isomerization" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]
null
null
true
true
3
GO:0000413
413
protein peptidyl-prolyl isomerization
biological_process
The modification of a protein by cis-trans isomerization of a proline residue.
[ "GOC:krc", "PMID:16959570" ]
null
[ "protein proline isomerization" ]
[ "EXACT" ]
[]
[ "gocheck_obsoletion_candidate" ]
[]
[ "GO:0018208" ]
[]
[]
[]
[ "GO:0018208" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0000414
414
obsolete regulation of histone H3-K36 methylation
biological_process
OBSOLETE. Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3.
[ "GOC:krc" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0140673" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]
null
null
true
true
7
GO:0000415
415
obsolete negative regulation of histone H3-K36 methylation
biological_process
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3.
[ "GOC:krc" ]
This term was obsoleted because it represents a molecular function.
[ "down regulation of histone H3-K36 methylation", "down-regulation of histone H3-K36 methylation", "downregulation of histone H3-K36 methylation", "inhibition of histone H3-K36 methylation" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006338" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]
null
null
true
true
1
GO:0000416
416
obsolete positive regulation of histone H3-K36 methylation
biological_process
OBSOLETE. Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3.
[ "GOC:krc" ]
This term was obsoleted because it represents a molecular function.
[ "activation of histone H3-K36 methylation", "stimulation of histone H3-K36 methylation", "up regulation of histone H3-K36 methylation", "up-regulation of histone H3-K36 methylation", "upregulation of histone H3-K36 methylation" ]
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0046975" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]
null
null
true
true
1
GO:0000417
417
HIR complex
cellular_component
A protein complex proposed to be involved in replication-independent nucleosome assembly, by promoting histone deposition onto DNA. For example, in Saccharomyces, the complex contains Hir1p, Hir2p, Hir3p, and Hpc2p.
[ "GOC:elh", "GOC:mah", "PMID:16303565", "PMID:17180700" ]
null
[ "HIRA complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0000418
418
RNA polymerase IV complex
cellular_component
RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and seco...
[ "GOC:krc", "GOC:mtg_sensu", "PMID:15692015", "PMID:15766525", "PMID:16140984", "PMID:19110459" ]
null
[ "DNA-directed RNA polymerase IV complex", "DNA-directed RNA polymerase IVa complex" ]
[ "EXACT", "EXACT" ]
[ "GO:0000420" ]
[]
[]
[ "GO:0000428", "GO:0140513" ]
[]
[]
[]
[ "GO:0000428", "GO:0140513" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0000419
419
RNA polymerase V complex
cellular_component
RNA polymerase V is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol V is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. Two large subunits com...
[ "GOC:krc", "GOC:mtg_sensu", "PMID:16140984", "PMID:19110459" ]
null
[ "DNA-directed RNA polymerase IVb complex", "DNA-directed RNA polymerase V complex" ]
[ "EXACT", "EXACT" ]
[ "GO:0080137" ]
[]
[]
[ "GO:0000428", "GO:0140513" ]
[]
[]
[]
[ "GO:0000428", "GO:0140513" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0000421
421
autophagosome membrane
cellular_component
The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered.
[ "GOC:autophagy", "GOC:isa_complete" ]
null
[ "autophagic vacuole membrane" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0005774" ]
[ "part_of GO:0005776" ]
[ "part_of" ]
[ "GO:0005776" ]
[ "GO:0005774", "GO:0005776" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0000423
423
mitophagy
biological_process
The selective autophagy process in which a mitochondrion is degraded by macroautophagy.
[ "PMID:15798367" ]
Note that this terms refers to the macroautophagy process and is named by common usage. Be aware that there are a separate micromitophagy and mitophagy by induced vacuole formation processes.
[ "macromitophagy" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-5205647 \"Mitophagy\"", "Wikipedia:Mitophagy" ]
[ "GO:0000422", "GO:0016236" ]
[]
[]
[]
[ "GO:0000422", "GO:0016236" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0000424
424
micromitophagy
biological_process
Degradation of a mitochondrion by microautophagy.
[ "PMID:15798367", "PMID:27003723" ]
Note that this term is not a child of mitophagy because the community generally uses the latter to refer to the macroautophagy of mitochondria.
[]
[]
[]
[]
[]
[ "GO:0000422", "GO:0016237" ]
[]
[]
[]
[ "GO:0000422", "GO:0016237" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25541\" xsd:anyURI" ]
null
null
false
true
1
GO:0000425
425
pexophagy
biological_process
The selective autophagy process in which a peroxisome is degraded by macroautophagy.
[ "GOC:autophagy", "PMID:12914914", "PMID:16973210" ]
null
[ "macropexophagy" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-9664873 \"Pexophagy\"" ]
[ "GO:0016236", "GO:0030242" ]
[]
[]
[]
[ "GO:0016236", "GO:0030242" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0000426
426
micropexophagy
biological_process
Degradation of a peroxisome by microautophagy.
[ "GOC:autophagy", "GOC:pad", "PMID:12914914", "PMID:15350980", "PMID:16973210" ]
Note that this term is not a child of pexophagy because the community usually uses the latter to refer to the macroautohagy process.
[]
[]
[]
[]
[]
[ "GO:0016237", "GO:0030242" ]
[]
[]
[]
[ "GO:0016237", "GO:0030242" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25541\" xsd:anyURI" ]
null
null
false
true
9
GO:0000427
427
plastid-encoded plastid RNA polymerase complex
cellular_component
An RNA polymerase complex containing polypeptides encoded by the plastid genome. Plastid-encoded DNA-directed RNA polymerases resemble eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. Some forms contain multiple additional subunits. An additional sigma factor subun...
[ "GOC:krc", "GOC:mah", "GOC:pj" ]
null
[]
[]
[]
[]
[]
[ "GO:0000428" ]
[ "part_of GO:0009536" ]
[ "part_of" ]
[ "GO:0009536" ]
[ "GO:0000428", "GO:0009536" ]
[ "GO:0000428", "part_of GO:0009536" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0000428
428
DNA-directed RNA polymerase complex
cellular_component
A protein complex that possesses DNA-directed RNA polymerase activity.
[ "GOC:krc" ]
null
[]
[]
[]
[]
[]
[ "GO:0030880" ]
[]
[]
[]
[ "GO:0030880" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0000429
429
carbon catabolite regulation of transcription from RNA polymerase II promoter
biological_process
A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.
[ "GOC:krc", "GOC:mah" ]
null
[ "regulation of transcription from RNA polymerase II promoter by carbon catabolites" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006357", "GO:0045990" ]
[]
[]
[]
[ "GO:0006357", "GO:0045990" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0000431
431
regulation of transcription from RNA polymerase II promoter by galactose
biological_process
Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
[ "GOC:krc" ]
null
[]
[]
[]
[]
[]
[ "GO:0000409", "GO:0000429" ]
[]
[]
[]
[ "GO:0000409", "GO:0000429" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0000432
432
positive regulation of transcription from RNA polymerase II promoter by glucose
biological_process
Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter.
[ "GOC:krc" ]
null
[ "activation of transcription from RNA polymerase II promoter by glucose", "stimulation of transcription from RNA polymerase II promoter by glucose", "up regulation of transcription from RNA polymerase II promoter by glucose", "up-regulation of transcription from RNA polymerase II promoter by glucose", "upre...
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0000430", "GO:0000436", "GO:0046016" ]
[]
[]
[]
[ "GO:0000430", "GO:0000436", "GO:0046016" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0000433
433
carbon catabolite repression of transcription from RNA polymerase II promoter by glucose
biological_process
A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific RNA polymerase II-transcribed genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accum...
[ "GOC:krc" ]
null
[ "down regulation of transcription from RNA polymerase II promoter by glucose", "down-regulation of transcription from RNA polymerase II promoter by glucose", "downregulation of transcription from RNA polymerase II promoter by glucose", "inhibition of transcription from RNA polymerase II promoter by glucose" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0045014", "GO:0061987" ]
[]
[]
[]
[ "GO:0045014", "GO:0061987" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0000434
434
carbon catabolite repression of transcription from RNA polymerase II promoter by galactose
biological_process
Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.
[ "GOC:krc" ]
null
[ "down regulation of transcription from RNA polymerase II promoter by galactose", "down-regulation of transcription from RNA polymerase II promoter by galactose", "downregulation of transcription from RNA polymerase II promoter by galactose", "inhibition of transcription from RNA polymerase II promoter by gala...
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0000410", "GO:0000431", "GO:0000437" ]
[]
[]
[]
[ "GO:0000410", "GO:0000431", "GO:0000437" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0000435
435
positive regulation of transcription from RNA polymerase II promoter by galactose
biological_process
Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter.
[ "GOC:krc" ]
null
[ "activation of transcription from RNA polymerase II promoter by galactose", "stimulation of transcription from RNA polymerase II promoter by galactose", "up regulation of transcription from RNA polymerase II promoter by galactose", "up-regulation of transcription from RNA polymerase II promoter by galactose",...
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0000411", "GO:0000431", "GO:0000436" ]
[]
[]
[]
[ "GO:0000411", "GO:0000431", "GO:0000436" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0000436
436
carbon catabolite activation of transcription from RNA polymerase II promoter
biological_process
Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
[ "GOC:krc" ]
null
[ "positive regulation of transcription from RNA polymerase II promoter by carbon catabolites" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0000429", "GO:0045944", "GO:0045991" ]
[]
[]
[]
[ "GO:0000429", "GO:0045944", "GO:0045991" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0000437
437
carbon catabolite repression of transcription from RNA polymerase II promoter
biological_process
A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.
[ "GOC:krc" ]
null
[ "negative regulation of transcription from RNA polymerase II promoter by carbon catabolites" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0000122", "GO:0000429", "GO:0045013" ]
[]
[]
[]
[ "GO:0000122", "GO:0000429", "GO:0045013" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0000438
438
core TFIIH complex portion of holo TFIIH complex
cellular_component
The core TFIIH complex when it is part of the general transcription factor TFIIH.
[ "GOC:ew", "GOC:krc", "PMID:14500720", "PMID:22308316", "PMID:22572993", "PMID:7813015" ]
null
[ "SSL2-core TFIIH complex portion of holo TFIIH complex" ]
[ "EXACT" ]
[ "GO:0000443" ]
[]
[]
[ "GO:0000439" ]
[ "part_of GO:0005675" ]
[ "part_of" ]
[ "GO:0005675" ]
[ "GO:0000439", "GO:0005675" ]
[ "GO:0000439", "part_of GO:0005675" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0000439
439
transcription factor TFIIH core complex
cellular_component
The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or the nucleotide-excision repair factor 3 complex. In S. cerevisiae/humans the complex is composed of: Ssl2/XPB, Tfb1/p62, Tfb2/p52, Ssl1/p44, Tfb4/p34, Tfb5/p8 and Rad3/XPD.
[ "GOC:ew", "GOC:krc", "PMID:14500720", "PMID:17215295", "PMID:22308316", "PMID:22572993", "PMID:23028141", "PMID:7813015" ]
null
[ "core TFIIH complex", "SSL2-core TFIIH complex" ]
[ "EXACT", "EXACT" ]
[ "GO:0000441" ]
[ "goslim_pir" ]
[]
[ "GO:0090575" ]
[]
[]
[]
[ "GO:0090575" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0000444
444
MIS12/MIND type complex
cellular_component
A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1.
[ "GOC:krc", "PMID:14633972", "PMID:16585270" ]
null
[ "MIND complex", "Mis12 complex", "Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex", "nuclear MIS12/MIND complex" ]
[ "EXACT", "NARROW", "RELATED", "RELATED" ]
[ "GO:0000818" ]
[]
[]
[ "GO:0000940" ]
[]
[]
[]
[ "GO:0000940" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23604\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23605\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25474\" xsd:anyURI" ]
null
null
false
true
4
GO:0000447
447
endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
[ "GOC:curators", "PMID:10690410" ]
null
[ "endonucleolytic cleavage at A2" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0000479" ]
[ "part_of GO:0000462", "part_of GO:0000466" ]
[ "part_of", "part_of" ]
[ "GO:0000462", "GO:0000466" ]
[ "GO:0000462", "GO:0000466", "GO:0000479" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0000448
448
cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Endonucleolytic cleavage within ITS2 between the 5.8S rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
[ "GOC:curators", "PMID:10690410" ]
null
[ "cleavage at C2", "cleavage in ITS2 of tricistronic rRNA transcript to separate 5.8S and LSU rRNAs (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" ]
[ "RELATED", "EXACT" ]
[ "GO:0000490" ]
[]
[]
[ "GO:0000479" ]
[ "part_of GO:0000463", "part_of GO:0000466" ]
[ "part_of", "part_of" ]
[ "GO:0000463", "GO:0000466" ]
[ "GO:0000463", "GO:0000466", "GO:0000479" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0000449
449
endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)
biological_process
Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. For example, primary ribosomal RNA transcripts containing three gene...
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0000450
450
cleavage of bicistronic rRNA transcript (SSU-rRNA, LSU-rRNA)
biological_process
Endonucleolytic cleavage of pre-rRNAs originally produced as a bicistronic rRNA transcript that contains the SSU-rRNA and the LSU-rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with two genes in this order are produced in Archaeal species.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0000451
451
rRNA 2'-O-methylation
biological_process
The addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an rRNA molecule during ribosome biogenesis.
[ "GOC:curators", "ISBN:1555811337" ]
null
[]
[]
[]
[]
[]
[ "GO:0031167" ]
[]
[]
[]
[ "GO:0031167" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0000452
452
snoRNA guided rRNA 2'-O-methylation
biological_process
The posttranscriptional addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of methylation.
[ "GOC:curators", "ISBN:1555811337" ]
null
[ "snoRNA guided rRNA 2'-O-ribose methylation" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0000451" ]
[]
[]
[]
[ "GO:0000451" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0000453
453
obsolete enzyme-directed rRNA 2'-O-methylation
biological_process
OBSOLETE. The addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis where the methylase specifies the site that becomes methylated without using a guide RNA.
[ "GOC:curators", "ISBN:1555811337" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006364" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24318\" xsd:anyURI" ]
null
null
true
true
7
GO:0000454
454
snoRNA guided rRNA pseudouridine synthesis
biological_process
The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation.
[ "GOC:curators", "ISBN:1555811337" ]
null
[]
[]
[]
[]
[]
[ "GO:0031118" ]
[]
[]
[]
[ "GO:0031118" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0000455
455
enzyme-directed rRNA pseudouridine synthesis
biological_process
The intramolecular conversion of uridine to pseudouridine during ribosome biogenesis where the enzyme specifies the site that becomes pseudouridylated without using a guide RNA.
[ "GOC:curators", "ISBN:1555811337" ]
null
[]
[]
[]
[]
[]
[ "GO:0031118" ]
[]
[]
[]
[ "GO:0031118" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0000457
457
endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)
biological_process
Endonucleolytic cleavage to separate a pre-SSU-rRNA from a pre-LSU-rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic r...
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0000449" ]
[ "part_of GO:0002108", "part_of GO:0002109" ]
[ "part_of", "part_of" ]
[ "GO:0002108", "GO:0002109" ]
[ "GO:0000449", "GO:0002108", "GO:0002109" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0000459
459
obsolete exonucleolytic trimming involved in rRNA processing
biological_process
OBSOLETE. Exonucleolytic digestion of a pre-rRNA molecule in the process to generate a mature rRNA molecule.
[ "GOC:curators" ]
The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
[ "exonucleolytic trimming during rRNA processing" ]
[ "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006364" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25184\" xsd:anyURI" ]
null
null
true
true
2
GO:0000460
460
maturation of 5.8S rRNA
biological_process
Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0000461
461
endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Endonucleolytic cleavage at the 3'-end of the SSU-rRNA from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA.
[ "GOC:krc", "PMID:10690410" ]
null
[ "endonucleolytic cleavage at site D" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0000479", "GO:0031125" ]
[ "part_of GO:0000462" ]
[ "part_of" ]
[ "GO:0000462" ]
[ "GO:0000462", "GO:0000479", "GO:0031125" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0000462
462
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5...
[ "GOC:curators" ]
null
[ "maturation of 18S rRNA" ]
[ "NARROW" ]
[ "GO:1990041" ]
[]
[]
[ "GO:0030490" ]
[]
[]
[]
[ "GO:0030490" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0000463
463
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to...
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0000470" ]
[]
[]
[]
[ "GO:0000470" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0000464
464
endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Endonucleolytic cleavage within Internal Transcribed Spacer 1 (ITS1) upstream of the 5.8S rRNA derived from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, ...
[ "GOC:krc", "PMID:10690410" ]
null
[ "endonucleolytic cleavage at A3" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0000479" ]
[ "part_of GO:0000463", "part_of GO:0000466" ]
[ "part_of", "part_of" ]
[ "GO:0000463", "GO:0000466" ]
[ "GO:0000463", "GO:0000466", "GO:0000479" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0000465
465
exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.
[ "GOC:krc", "PMID:10690410" ]
null
[]
[]
[]
[]
[]
[ "GO:0000967" ]
[ "part_of GO:0000466" ]
[ "part_of" ]
[ "GO:0000466" ]
[ "GO:0000466", "GO:0000967" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0000467
467
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.
[ "GOC:krc", "PMID:10690410" ]
null
[]
[]
[]
[]
[]
[ "GO:0031125" ]
[ "part_of GO:0000466" ]
[ "part_of" ]
[ "GO:0000466" ]
[ "GO:0000466", "GO:0031125" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0000468
468
generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Any process involved in generating the mature 3'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
[ "GOC:krc", "PMID:10690410" ]
null
[ "processing at B2" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0031125" ]
[ "part_of GO:0000463" ]
[ "part_of" ]
[ "GO:0000463" ]
[ "GO:0000463", "GO:0031125" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0000469
469
obsolete cleavage involved in rRNA processing
biological_process
OBSOLETE. Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule.
[ "GOC:curators" ]
The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
[ "cleavage during rRNA processing" ]
[ "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006364" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25184\" xsd:anyURI" ]
null
null
true
true
3
GO:0000470
470
maturation of LSU-rRNA
biological_process
Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0006364" ]
[ "part_of GO:0042273" ]
[ "part_of" ]
[ "GO:0042273" ]
[ "GO:0006364", "GO:0042273" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0000471
471
endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Endonucleolytic cleavage within the 3'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of...
[ "GOC:krc", "PMID:10690410" ]
null
[]
[]
[]
[]
[]
[ "GO:0000479" ]
[]
[]
[]
[ "GO:0000479" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0000472
472
endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Endonucleolytic cleavage between the 5'-External Transcribed Spacer (5'-ETS) and the 5' end of the SSU-rRNA of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of...
[ "GOC:curators", "PMID:10690410" ]
null
[ "endonucleolytic cleavage at A1" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0000479", "GO:0000967" ]
[ "part_of GO:0000462" ]
[ "part_of" ]
[ "GO:0000462" ]
[ "GO:0000462", "GO:0000479", "GO:0000967" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0000473
473
maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
biological_process
Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that orde...
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0000470" ]
[]
[]
[]
[ "GO:0000470" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0000474
474
maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
biological_process
Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that orde...
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0030490" ]
[]
[]
[]
[ "GO:0030490" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0000475
475
maturation of 2S rRNA
biological_process
Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0000476
476
maturation of 4.5S rRNA
biological_process
Any process involved in the maturation of a precursor 4.5S ribosomal RNA (rRNA) molecule into a mature 4.5S rRNA molecule.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0000477
477
generation of mature 5'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Cleavage within ITS2 to generate the mature 5'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
[ "GOC:curators", "PMID:10690410" ]
null
[ "processing at C1" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0000967" ]
[ "part_of GO:0000463" ]
[ "part_of" ]
[ "GO:0000463" ]
[ "GO:0000463", "GO:0000967" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0000479
479
endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with three genes, in this order,...
[ "GOC:curators", "PMID:10690410" ]
null
[]
[]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0000480
480
endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is co...
[ "GOC:curators", "PMID:10690410", "PMID:15282326" ]
null
[ "endonucleolytic cleavage at A-prime", "endonucleolytic cleavage at A0" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0000479" ]
[ "part_of GO:0000462" ]
[ "part_of" ]
[ "GO:0000462" ]
[ "GO:0000462", "GO:0000479" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0000481
481
maturation of 5S rRNA
biological_process
Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0000482
482
maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
biological_process
Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to...
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0000481" ]
[]
[]
[]
[ "GO:0000481" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0000483
483
endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
biological_process
Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in t...
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[ "GO:0006364" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0000484
484
cleavage between SSU-rRNA and 5.8S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
biological_process
Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0000483" ]
[ "part_of GO:0000474", "part_of GO:0000487" ]
[ "part_of", "part_of" ]
[ "GO:0000474", "GO:0000487" ]
[ "GO:0000474", "GO:0000483", "GO:0000487" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0000485
485
cleavage between 2S rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
biological_process
Endonucleolytic cleavage between the LSU-rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
[ "GOC:curators", "PMID:768488" ]
null
[]
[]
[]
[]
[]
[ "GO:0000483" ]
[ "part_of GO:0000473", "part_of GO:0000475" ]
[ "part_of", "part_of" ]
[ "GO:0000473", "GO:0000475" ]
[ "GO:0000473", "GO:0000475", "GO:0000483" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0000486
486
cleavage between 5.8S rRNA and 2S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
biological_process
Endonucleolytic cleavage between the 5.8S rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
[ "GOC:curators", "PMID:768488" ]
null
[]
[]
[]
[]
[]
[ "GO:0000483" ]
[ "part_of GO:0000475", "part_of GO:0000487" ]
[ "part_of", "part_of" ]
[ "GO:0000475", "GO:0000487" ]
[ "GO:0000475", "GO:0000483", "GO:0000487" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0000487
487
maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)
biological_process
Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 8.8S rRNA, the 2S rRNA, and the Large Subunit (LSU) in that order f...
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0000460" ]
[]
[]
[]
[ "GO:0000460" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0000488
488
maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)
biological_process
Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in tha...
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0000470" ]
[]
[]
[]
[ "GO:0000470" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0000489
489
maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)
biological_process
Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in tha...
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0030490" ]
[]
[]
[]
[ "GO:0030490" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0000491
491
small nucleolar ribonucleoprotein complex assembly
biological_process
The aggregation, arrangement and bonding together of proteins and a snoRNA to form a small nucleolar ribonucleoprotein (snoRNP) complex.
[ "GOC:krc" ]
null
[ "snoRNP assembly" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0022618" ]
[]
[]
[]
[ "GO:0022618" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0000492
492
box C/D snoRNP assembly
biological_process
The aggregation, arrangement and bonding together of proteins and a box C/D snoRNA to form a box C/D small nucleolar ribonucleoprotein (snoRNP) complex.
[ "GOC:krc" ]
null
[ "box C/D small nucleolar ribonucleoprotein complex assembly" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0000491" ]
[]
[]
[]
[ "GO:0000491" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0000493
493
box H/ACA snoRNP assembly
biological_process
The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex.
[ "GOC:krc", "PMID:12515383" ]
null
[ "box H/ACA small nucleolar ribonucleoprotein complex assembly" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0000491" ]
[]
[]
[]
[ "GO:0000491" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0000494
494
box C/D sno(s)RNA 3'-end processing
biological_process
Any process involved in forming the mature 3' end of a box C/D RNA molecule.
[ "GOC:krc" ]
null
[ "box C/D RNA 3' end processing", "box C/D snoRNA 3'-end processing", "box C/D sRNA 3'-end processing" ]
[ "EXACT", "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0031126", "GO:0034963" ]
[]
[]
[]
[ "GO:0031126", "GO:0034963" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20416\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26930\" xsd:anyURI" ]
null
null
false
true
7
GO:0000495
495
box H/ACA sno(s)RNA 3'-end processing
biological_process
Any process involved in forming the mature 3' end of a box H/ACA RNA molecule.
[ "GOC:krc" ]
null
[ "box H/ACA RNA 3' end processing", "box H/ACA snoRNA 3'-end processing", "box H/ACA sRNA 3'-end processing" ]
[ "EXACT", "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0031126", "GO:0034964" ]
[]
[]
[]
[ "GO:0031126", "GO:0034964" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20416\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26930\" xsd:anyURI" ]
null
null
false
true
3
GO:0000497
497
DNA template activity
molecular_function
Binding to nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target DNA molecule.
[ "GOC:krc" ]
Note that with respect to annotation, "base pairing" and its child terms are intended to be used to annotate the activity of gene products composed of nucleic acid, presumably RNA, to interact with DNA molecules via base pairing. Internal base pairing with itself is considered part of the secondary structure of the mol...
[ "base pairing with DNA" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0003677", "GO:0140489" ]
[]
[]
[]
[ "GO:0003677", "GO:0140489" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0000500
500
RNA polymerase I upstream activating factor complex
cellular_component
A complex required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrrn5p, Rrn9p, Rrn10p, histones H3 and H4, and Uaf30p.
[ "PMID:11500378" ]
null
[ "RNA polymerase I upstream activation factor complex", "UAF" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0000120" ]
[]
[]
[]
[ "GO:0000120" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0000502
502
proteasome complex
cellular_component
A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.
[ "GOC:rb", "Wikipedia:Proteasome" ]
null
[ "26S proteasome", "proteasome" ]
[ "NARROW", "EXACT" ]
[]
[ "goslim_pir" ]
[]
[ "GO:0140535", "GO:1905369" ]
[]
[]
[]
[ "GO:0140535", "GO:1905369" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0000504
504
obsolete proteasome regulatory particle (sensu Bacteria)
cellular_component
OBSOLETE. A multisubunit complex that recognizes and unfolds ubiquitinated proteins, and translocates them to the core complex in an ATP dependent manner. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).
[ "GOC:rb" ]
This term was made obsolete because there is no ubiquitin in bacteria and they do not have proteasome regulatory particles. Instead they have proteasome-activating nucleotidase.
[ "26S proteasome", "proteasome regulatory particle (sensu Bacteria)" ]
[ "NARROW", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
4
GO:0000511
511
H2A-H2B histone complex chaperone activity
molecular_function
A histone chaperone that carries a H2A-H2B histone complex.
[ "PMID:28053344" ]
null
[ "H2A-H2B histone carrier activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140713" ]
[]
[]
[]
[ "GO:0140713" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21733\" xsd:anyURI" ]
pg
2021-09-10T15:22:31Z
false
true
3
GO:0000512
512
lncRNA-mediated post-transcriptional gene silencing
biological_process
A post-transcriptional gene silencing pathway in which regulatory long noncoding RNAs (lncRNAs) elicit silencing of specific target genes, often miRNAs or mRNAs.
[ "PMID:34454184", "PMID:35055152" ]
This term should be applied to lncRNAs and proteins associated with this process and not to the target (miRNAs or mRNAs) of the process.
[ "lncRNA-mediated gene silencing" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0035194" ]
[]
[]
[]
[ "GO:0035194" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23020\" xsd:anyURI" ]
pg
2022-03-16T07:57:55Z
false
true
3