go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0070025
70,025
carbon monoxide binding
molecular_function
Binding to carbon monoxide (CO).
[ "GOC:ecd" ]
null
[ "CO binding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0036094" ]
[]
[]
[]
[ "GO:0036094" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21211\" xsd:anyURI" ]
null
null
false
true
3
GO:0070027
70,027
carbon monoxide sensor activity
molecular_function
Binding to and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO).
[ "GOC:ecd" ]
null
[ "carbon monoxide sensing activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140299" ]
[ "has_part GO:0070025" ]
[ "has_part" ]
[ "GO:0070025" ]
[ "GO:0070025", "GO:0140299" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25267\" xsd:anyURI" ]
null
null
false
true
5
GO:0070028
70,028
obsolete regulation of transcription by carbon monoxide
biological_process
OBSOLETE. Any process involving carbon monoxide that modulates the frequency, rate or extent of transcription.
[ "GOC:ecd" ]
This term was obsoleted because it represents a GO-CAM model.
[ "regulation of transcription by CO" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006357" ]
[]
null
null
true
true
7
GO:0070029
70,029
alphav-beta3 integrin-osteopontin complex
cellular_component
A protein complex that consists of an alphav-beta3 integrin complex bound to osteopontin.
[ "PMID:7532190" ]
null
[ "ITGAV-ITGB3-SPP1 complex" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0098797" ]
[]
[]
[]
[ "GO:0098797" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0070030
70,030
alphav-beta1 integrin-osteopontin complex
cellular_component
A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin.
[ "PMID:7592829" ]
null
[ "ITGAV-ITGB1-SPP1 complex" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0098797" ]
[]
[]
[]
[ "GO:0098797" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0070031
70,031
alphav-beta5 integrin-osteopontin complex
cellular_component
A protein complex that consists of an alphav-beta5 integrin complex bound to osteopontin.
[ "PMID:7592829" ]
null
[ "ITGAV-ITGB5-SPP1 complex" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0098797" ]
[]
[]
[]
[ "GO:0098797" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0070033
70,033
synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex
cellular_component
A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin II (or orthologs thereof).
[ "PMID:7553862" ]
null
[ "SNARE complex (Vamp2, Snap25, Stx1a, Cplx2)", "Vamp2-Snap25-Stx1a-Cplx2 complex" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0070034
70,034
telomerase RNA binding
molecular_function
Binding to the telomerase RNA template.
[ "GOC:krc", "PMID:16884717" ]
null
[ "TERC binding" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0003723" ]
[]
[]
[]
[ "GO:0003723" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0070035
70,035
obsolete purine NTP-dependent helicase activity
molecular_function
OBSOLETE. Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix.
[ "GOC:mah" ]
The reason for obsoletion is that helicases only and always use ATP (although under very specific experimental conditions GTP can perhaps be used; this is not the case in vivo), therefore this term was an unnecessary grouping term.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
2
GO:0070036
70,036
obsolete GTP-dependent helicase activity
molecular_function
OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate, to drive the unwinding of a DNA or RNA helix.
[ "GOC:mah" ]
The reason for obsoletion is that helicases only and always use ATP (although under very specific experimental conditions GTP can perhaps be used; this is not the case in vivo).
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
4
GO:0070037
70,037
rRNA (pseudouridine) methyltransferase activity
molecular_function
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule.
[ "GOC:imk", "GOC:mah" ]
null
[]
[]
[]
[]
[ "Reactome:R-HSA-6790906 \"EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248\"" ]
[ "GO:0008649" ]
[]
[]
[]
[ "GO:0008649" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0070038
70,038
rRNA (pseudouridine-N3-)-methyltransferase activity
molecular_function
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine.
[ "GOC:imk", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0070037" ]
[]
[]
[]
[ "GO:0070037" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0070039
70,039
rRNA (guanosine-2'-O-ribose)-methyltransferase activity
molecular_function
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine.
[ "GOC:imk", "GOC:mah" ]
null
[ "rRNA (guanosine-2'-O-)-methyltransferase activity" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-6793096 \"MRM3 (RNMTL1) methylates guanosine-1370 of 16S rRNA yielding 2'-O-methylguanosine-1370\"", "Reactome:R-HSA-6793122 \"MRM1 methylates guanosine-1145 of 16S rRNA yielding 2'-O-methylguanosine-1145\"" ]
[ "GO:0016435", "GO:0062105" ]
[ "part_of GO:0000451" ]
[ "part_of" ]
[ "GO:0000451" ]
[ "GO:0000451", "GO:0016435", "GO:0062105" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:58956", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
null
null
false
true
8
GO:0070040
70,040
rRNA (adenine(2503)-C2-)-methyltransferase activity
molecular_function
Catalysis of the reaction: adenosine2503 in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine2503 in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine.
[ "GOC:imk", "PMID:20007606", "PMID:20184321", "PMID:21368151", "PMID:21415317", "PMID:21527678", "RHEA:42916" ]
null
[ "rRNA (adenine-C2-)-methyltransferase activity" ]
[ "BROAD" ]
[]
[]
[ "MetaCyc:RXN-11586", "RHEA:42916" ]
[ "GO:0008169", "GO:0016433" ]
[]
[]
[]
[ "GO:0008169", "GO:0016433" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.1.1.192", "skos:exactMatch RHEA:42916", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26114\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28183\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-onto...
null
null
false
true
9
GO:0070041
70,041
rRNA (uridine-C5-)-methyltransferase activity
molecular_function
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.
[ "GOC:imk", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0008169", "GO:0016436" ]
[]
[]
[]
[ "GO:0008169", "GO:0016436" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0070042
70,042
rRNA (uridine-N3-)-methyltransferase activity
molecular_function
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine.
[ "GOC:imk", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0008170", "GO:0016436" ]
[]
[]
[]
[ "GO:0008170", "GO:0016436" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0070043
70,043
rRNA (guanine-N7-)-methyltransferase activity
molecular_function
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.
[ "GOC:imk", "GOC:mah" ]
null
[]
[]
[]
[]
[ "Reactome:R-HSA-6790982 \"WBSCR22:TRMT112 methylates guanosine-1639 of 18S rRNA yielding 7-methylguanosine-1639\"" ]
[ "GO:0008170", "GO:0016435" ]
[ "part_of GO:0070476" ]
[ "part_of" ]
[ "GO:0070476" ]
[ "GO:0008170", "GO:0016435", "GO:0070476" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0070044
70,044
synaptobrevin 2-SNAP-25-syntaxin-1a complex
cellular_component
A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 1a (or orthologs thereof).
[ "PMID:10336434" ]
null
[ "Snap25-Stx1a-Vamp2 complex", "SNARE complex (Snap25, Stx1a, Vamp2)", "SNARE complex (Stx1a, SNAP25, VAMP)", "Stx1a-SNAP25-VAMP complex" ]
[ "NARROW", "NARROW", "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0070045
70,045
synaptobrevin 2-SNAP-25-syntaxin-2 complex
cellular_component
A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 2 (or orthologs thereof).
[ "PMID:10336434" ]
null
[ "SNARE complex (Stx2, Snap25, Vamp2)", "Stx2-Snap25-Vamp2 complex" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0070046
70,046
synaptobrevin 2-SNAP-25-syntaxin-3 complex
cellular_component
A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 3 (or orthologs thereof).
[ "PMID:10336434" ]
null
[ "SNARE complex (Stx3, Snap25, Vamp2)", "Stx3-Snap25-Vamp2 complex" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0070047
70,047
synaptobrevin 2-SNAP-25-syntaxin-4 complex
cellular_component
A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 4 (or orthologs thereof).
[ "PMID:10336434" ]
null
[ "SNARE complex (Stx4, Snap25, Vamp2)", "Stx4-Snap25-Vamp2 complex" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0070050
70,050
neuron cellular homeostasis
biological_process
The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state.
[ "GOC:BHF", "GOC:mah" ]
null
[ "neuron maintenance" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0019725" ]
[]
[]
[]
[ "GO:0019725" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24218\" xsd:anyURI" ]
null
null
false
true
9
GO:0070051
70,051
fibrinogen binding
molecular_function
Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade.
[ "GOC:BHF", "GOC:mah", "GOC:vk" ]
null
[]
[]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0070052
70,052
collagen V binding
molecular_function
Binding to a type V collagen trimer.
[ "GOC:BHF", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0005518" ]
[]
[]
[]
[ "GO:0005518" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0070053
70,053
thrombospondin receptor activity
molecular_function
Combining with thrombospondin and transmitting the signal to initiate a change in cell activity.
[ "GOC:BHF", "GOC:signaling", "GOC:vk" ]
null
[]
[]
[]
[]
[]
[ "GO:0038023" ]
[]
[]
[]
[ "GO:0038023" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0070054
70,054
mRNA splicing, via endonucleolytic cleavage and ligation
biological_process
Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
[ "GOC:krc", "GOC:mah" ]
Note that while typically associated with tRNA splicing, splicing via endonucleolytic cleavages and subsequent ligation of the free exon ends is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.
[ "cytosolic mRNA splicing" ]
[ "RELATED" ]
[ "GO:0061012" ]
[]
[]
[ "GO:0000394", "GO:0006397" ]
[]
[]
[]
[ "GO:0000394", "GO:0006397" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0070055
70,055
obsolete mRNA endonucleolytic cleavage involved in unfolded protein response
biological_process
OBSOLETE. The endonucleolytic cleavage of a mRNA containing an HAC1-type intron at the 5' and 3' splice sites. The cleavage step is part of unconventional mRNA splicing, and contributes to the endoplasmic reticulum unfolded protein response.
[ "GOC:bf", "GOC:krc", "GOC:mah", "PMID:10357823" ]
The reason for obsoletion is that this process represents a single step (molecular function) of the IRE1-mediated unfolded protein response (GO:0036498).
[ "ERN1-mediated XBP-1 mRNA cleavage", "HAC1 mRNA cleavage", "HAC1-type intron splice site recognition and cleavage", "IRE1-mediated XBP-1 mRNA cleavage", "XBP1 mRNA cleavage" ]
[ "RELATED", "NARROW", "NARROW", "NARROW", "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0036498" ]
[]
null
null
true
true
9
GO:0070056
70,056
prospore membrane leading edge
cellular_component
The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization.
[ "GOC:mah", "PMID:14702385" ]
null
[ "forespore membrane leading edge" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0016020" ]
[ "part_of GO:0005628" ]
[ "part_of" ]
[ "GO:0005628" ]
[ "GO:0005628", "GO:0016020" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0070057
70,057
prospore membrane spindle pole body attachment site
cellular_component
The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus.
[ "GOC:mah", "PMID:14702385" ]
null
[ "forespore membrane SPB attachment site", "forespore membrane spindle pole body attachment site", "prospore membrane SPB attachment site" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005628" ]
[ "part_of" ]
[ "GO:0005628" ]
[ "GO:0005628", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0070058
70,058
tRNA gene clustering
biological_process
The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. ce...
[ "GOC:jh", "GOC:mah", "PMID:18708579" ]
null
[]
[]
[]
[]
[]
[ "GO:0051276" ]
[]
[]
[]
[ "GO:0051276" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0070059
70,059
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
biological_process
The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulati...
[ "GOC:mah", "GOC:mtg_apoptosis", "PMID:18701708" ]
null
[ "apoptosis in response to endoplasmic reticulum stress", "apoptosis in response to ER stress", "apoptosis triggered by ER stress", "endoplasmic reticulum stress-induced apoptosis", "ER stress-induced apoptosis", "intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress" ]
[ "BROAD", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0034976", "GO:0097193" ]
[]
[]
[]
[ "GO:0034976", "GO:0097193" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0070060
70,060
'de novo' actin filament nucleation
biological_process
The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament.
[ "GOC:mah", "PMID:17477841" ]
null
[ "formin-mediated actin filament nucleation", "unbranched actin filament nucleation" ]
[ "NARROW", "RELATED" ]
[]
[]
[]
[ "GO:0045010" ]
[]
[]
[]
[ "GO:0045010" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0070061
70,061
fructose binding
molecular_function
Binding to the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.
[ "CHEBI:28757", "GOC:BHF", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0048029" ]
[]
[]
[]
[ "GO:0048029" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0070062
70,062
extracellular exosome
cellular_component
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
[ "GOC:BHF", "GOC:mah", "GOC:vesicles", "PMID:15908444", "PMID:17641064", "PMID:19442504", "PMID:19498381", "PMID:22418571", "PMID:24009894" ]
null
[ "exosome", "extracellular vesicular exosome" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1903561" ]
[]
[]
[]
[ "GO:1903561" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0070063
70,063
RNA polymerase binding
molecular_function
Binding to an RNA polymerase molecule or complex.
[ "GOC:BHF", "GOC:mah", "GOC:txnOH" ]
null
[]
[]
[]
[]
[]
[ "GO:0019899" ]
[]
[]
[]
[ "GO:0019899" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0070065
70,065
cellubrevin-VAMP4-syntaxin-16 complex
cellular_component
A SNARE complex that contains cellubrevin (VAMP3), VAMP4, and syntaxin 16 (or orthologs thereof).
[ "PMID:11839770" ]
null
[ "SNARE complex (Vamp3, Vamp4, Stx16)", "Vamp3-Vamp4-Stx16 complex" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0070066
70,066
cellubrevin-VAMP4-endobrevin-syntaxin-6 complex
cellular_component
A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof).
[ "PMID:11839770" ]
null
[ "SNARE complex (Vamp3, Vamp4, Vam8, Stx6)", "Vamp3-Vamp4-Vam8-Stx6 complex" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0070067
70,067
syntaxin-6-syntaxin-16-Vti1a complex
cellular_component
A SNARE complex that contains syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).
[ "PMID:11839770" ]
null
[]
[]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0070068
70,068
VAMP4-syntaxin-6-syntaxin-16-Vti1a complex
cellular_component
A SNARE complex that contains VAMP4, syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).
[ "PMID:11839770" ]
null
[ "SNARE complex (Vamp4, Stx6, Stx16, Vti1a)", "Vamp4-Stx6-Stx16-Vti1a complex" ]
[ "NARROW", "RELATED" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[ "GO:0031201" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0070070
70,070
proton-transporting V-type ATPase complex assembly
biological_process
The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient.
[ "GOC:mah" ]
null
[ "V-ATPase assembly", "V-ATPase complex assembly" ]
[ "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0070071" ]
[]
[]
[]
[ "GO:0070071" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0070071
70,071
proton-transporting two-sector ATPase complex assembly
biological_process
The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0065003" ]
[]
[]
[]
[ "GO:0065003" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0070072
70,072
vacuolar proton-transporting V-type ATPase complex assembly
biological_process
The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.
[ "GOC:BHF", "GOC:mah" ]
null
[ "V-ATPase assembly", "V-ATPase complex assembly" ]
[ "BROAD", "BROAD" ]
[]
[]
[]
[ "GO:0070070" ]
[]
[]
[]
[ "GO:0070070" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0070073
70,073
clustering of voltage-gated calcium channels
biological_process
The process in which voltage-gated calcium channels become localized together in high densities.
[ "GOC:BHF", "GOC:sart", "PMID:18385325" ]
null
[ "clustering of voltage gated calcium channels", "clustering of voltage-dependent calcium channels", "voltage-gated calcium channel clustering" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0045161" ]
[]
[]
[]
[ "GO:0045161" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0070074
70,074
mononeme
cellular_component
A secretory organelle that forms part of the apical complex; a small, threadlike structure located is close proximity to the subpellicular microtubules. Its contents include a rhomboid protease (PfROM1 in Plasmodium falciparum) that moves from the lateral asymmetric localization to the merozoite apical pole and the pos...
[ "GOC:BHF", "PMID:18048320" ]
null
[]
[]
[]
[]
[]
[ "GO:0043231" ]
[ "part_of GO:0020007" ]
[ "part_of" ]
[ "GO:0020007" ]
[ "GO:0020007", "GO:0043231" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0070075
70,075
tear secretion
biological_process
The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium.
[ "GOC:rph" ]
null
[]
[]
[]
[]
[]
[ "GO:0007589", "GO:0032941" ]
[]
[]
[]
[ "GO:0007589", "GO:0032941" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0070076
70,076
obsolete histone lysine demethylation
biological_process
OBSOLETE. The modification of a histone by the removal of a methyl group from a lysine residue.
[ "GOC:mah" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]
null
null
true
true
6
GO:0070077
70,077
obsolete histone arginine demethylation
biological_process
OBSOLETE. The modification of a histone by the removal of a methyl group from an arginine residue.
[ "GOC:mah" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0032452" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24261\" xsd:anyURI" ]
null
null
true
true
4
GO:0070078
70,078
obsolete histone H3-R2 demethylation
biological_process
OBSOLETE. The modification of histone H3 by the removal of a methyl group from arginine at position 2 of the histone.
[ "GOC:BHF", "GOC:vk" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]
null
null
true
true
8
GO:0070079
70,079
obsolete histone H4-R3 demethylation
biological_process
OBSOLETE. The modification of histone H4 by the removal of a methyl group from arginine at position 3 of the histone.
[ "GOC:BHF", "GOC:vk" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]
null
null
true
true
3
GO:0070080
70,080
titin Z domain binding
molecular_function
Binding to a titin Z protein domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34.
[ "GOC:mah", "InterPro:IPR015129" ]
null
[ "Z repeat domain binding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0019904" ]
[]
[]
[]
[ "GO:0019904" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0070081
70,081
clathrin-sculpted monoamine transport vesicle
cellular_component
A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing monoamines.
[ "GOC:mg2" ]
null
[ "clathrin sculpted monoamine constitutive secretory pathway transport vesicle", "clathrin sculpted monoamine transport vesicle" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0030133", "GO:0060198" ]
[]
[]
[]
[ "GO:0030133", "GO:0060198" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0070082
70,082
clathrin-sculpted monoamine transport vesicle lumen
cellular_component
The volume enclosed by the membrane of the clathrin-sculpted monoamine transport vesicle.
[ "GOC:mg2" ]
null
[ "clathrin sculpted monoamine constitutive secretory pathway transport vesicle lumen", "clathrin sculpted monoamine transport vesicle lumen" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0060205" ]
[ "part_of GO:0070081" ]
[ "part_of" ]
[ "GO:0070081" ]
[ "GO:0060205", "GO:0070081" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0070083
70,083
clathrin-sculpted monoamine transport vesicle membrane
cellular_component
The lipid bilayer surrounding a clathrin-sculpted monoamine transport vesicle.
[ "GOC:mg2" ]
null
[ "clathrin sculpted monoamine constitutive secretory pathway transport vesicle membrane", "clathrin sculpted monoamine transport vesicle membrane" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0030658", "GO:0030665" ]
[ "part_of GO:0070081" ]
[ "part_of" ]
[ "GO:0070081" ]
[ "GO:0030658", "GO:0030665", "GO:0070081" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0070084
70,084
obsolete protein initiator methionine removal
biological_process
OBSOLETE. The protein modification process in which the translation-initiating methionine or formylmethionine residue is removed from a protein.
[ "GOC:imk", "GOC:mah" ]
The reason for obsoletion is that this term represents a molecular function.
[ "removal of initiator methionine from protein" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25210\" xsd:anyURI" ]
null
null
true
true
4
GO:0070085
70,085
obsolete glycosylation
biological_process
OBSOLETE. The covalent attachment and further modification of carbohydrate residues to a substrate molecule.
[ "GOC:hjd", "GOC:mah" ]
The reason for obsoletion is that this term represents a molecular function.
[]
[]
[]
[]
[ "Wikipedia:Glycosylation" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30371\" xsd:anyURI" ]
null
null
true
true
1
GO:0070087
70,087
chromo shadow domain binding
molecular_function
Binding to a chromo shadow domain, a protein domain that is distantly related, and found in association with, the chromo domain.
[ "GOC:BHF", "GOC:vk", "InterPro:IPR008251", "PMID:7667093" ]
null
[ "chromoshadow domain binding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0019904" ]
[]
[]
[]
[ "GO:0019904" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0070088
70,088
polyhydroxyalkanoate granule
cellular_component
An inclusion body located in the cytoplasm of prokaryotes that consists of polyhydroxyalkanoate (PHA) molecules and associated proteins, surrounded by a phospholipid monolayer; the proteins include PHA synthase, PHA depolymerase and 3HB-oligomer hydroxylase, phasins (PhaPs), which are thought to be the major structural...
[ "GOC:mah", "PMID:15762612" ]
null
[ "carbonosome", "PHA granule", "PHB granule" ]
[ "BROAD", "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0016234", "GO:0043231" ]
[ "part_of GO:0005737" ]
[ "part_of" ]
[ "GO:0005737" ]
[ "GO:0005737", "GO:0016234", "GO:0043231" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24423\" xsd:anyURI" ]
null
null
false
true
2
GO:0070089
70,089
chloride-activated potassium channel activity
molecular_function
Enables the transmembrane transfer of a potassium cation by a channel that opens when a chloride ion has been bound by the channel complex or one of its constituent parts.
[ "GOC:kmv", "GOC:mtg_transport" ]
null
[]
[]
[]
[]
[]
[ "GO:0005267", "GO:0022839", "GO:0099094" ]
[]
[]
[]
[ "GO:0005267", "GO:0022839", "GO:0099094" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24605\" xsd:anyURI" ]
null
null
false
true
5
GO:0070090
70,090
metaphase plate
cellular_component
The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0005622" ]
[]
[]
[]
[ "GO:0005622" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0070091
70,091
glucagon secretion
biological_process
The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans).
[ "GOC:BHF", "GOC:rl" ]
null
[]
[]
[]
[]
[]
[ "GO:0030072" ]
[]
[]
[]
[ "GO:0030072" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0070092
70,092
regulation of glucagon secretion
biological_process
Any process that modulates the frequency, rate or extent of the regulated release of glucagon.
[ "GOC:BHF", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0090276" ]
[ "regulates GO:0070091" ]
[ "regulates" ]
[ "GO:0070091" ]
[ "GO:0070091", "GO:0090276" ]
[ "GO:0065007", "regulates GO:0070091" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0070093
70,093
negative regulation of glucagon secretion
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon.
[ "GOC:BHF", "GOC:mah" ]
null
[ "down regulation of glucagon secretion", "down-regulation of glucagon secretion", "downregulation of glucagon secretion", "inhibition of glucagon secretion" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0070092", "GO:0090278" ]
[ "negatively_regulates GO:0070091" ]
[ "negatively_regulates" ]
[ "GO:0070091" ]
[ "GO:0070091", "GO:0070092", "GO:0090278" ]
[ "GO:0065007", "negatively_regulates GO:0070091" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0070094
70,094
positive regulation of glucagon secretion
biological_process
Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon.
[ "GOC:BHF", "GOC:mah" ]
null
[ "activation of glucagon secretion", "stimulation of glucagon secretion", "up regulation of glucagon secretion", "up-regulation of glucagon secretion", "upregulation of glucagon secretion" ]
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0070092", "GO:0090277" ]
[ "positively_regulates GO:0070091" ]
[ "positively_regulates" ]
[ "GO:0070091" ]
[ "GO:0070091", "GO:0070092", "GO:0090277" ]
[ "GO:0065007", "positively_regulates GO:0070091" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0070095
70,095
fructose-6-phosphate binding
molecular_function
Binding to fructose 6-phosphate.
[ "GOC:mah" ]
null
[ "D-fructose 6-phosphate binding", "fructose 6-phosphate binding" ]
[ "NARROW", "EXACT" ]
[]
[]
[]
[ "GO:0043168", "GO:0097367" ]
[]
[]
[]
[ "GO:0043168", "GO:0097367" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0070098
70,098
chemokine-mediated signaling pathway
biological_process
The series of molecular signals initiated by a chemokine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
[ "GOC:mah", "GOC:signaling" ]
null
[ "chemokine-mediated signalling pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0007186", "GO:0019221" ]
[ "part_of GO:1990869" ]
[ "part_of" ]
[ "GO:1990869" ]
[ "GO:0007186", "GO:0019221", "GO:1990869" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26684\" xsd:anyURI" ]
null
null
false
true
7
GO:0070099
70,099
regulation of chemokine-mediated signaling pathway
biological_process
Any process that modulates the rate, frequency or extent of a chemokine-mediated signaling pathway.
[ "GOC:mah" ]
null
[ "regulation of chemokine-mediated signalling pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0001959", "GO:0008277" ]
[ "regulates GO:0070098" ]
[ "regulates" ]
[ "GO:0070098" ]
[ "GO:0001959", "GO:0008277", "GO:0070098" ]
[ "GO:0065007", "regulates GO:0070098" ]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0070100
70,100
negative regulation of chemokine-mediated signaling pathway
biological_process
Any process that decreases the rate, frequency or extent of a chemokine-mediated signaling pathway.
[ "GOC:mah" ]
null
[ "negative regulation of chemokine-mediated signalling pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0001960", "GO:0045744", "GO:0070099" ]
[ "negatively_regulates GO:0070098" ]
[ "negatively_regulates" ]
[ "GO:0070098" ]
[ "GO:0001960", "GO:0045744", "GO:0070098", "GO:0070099" ]
[ "GO:0065007", "negatively_regulates GO:0070098" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0070101
70,101
positive regulation of chemokine-mediated signaling pathway
biological_process
Any process that increases the rate, frequency or extent of a chemokine-mediated signaling pathway.
[ "GOC:mah" ]
null
[ "positive regulation of chemokine-mediated signalling pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0001961", "GO:0045745", "GO:0070099" ]
[ "positively_regulates GO:0070098" ]
[ "positively_regulates" ]
[ "GO:0070098" ]
[ "GO:0001961", "GO:0045745", "GO:0070098", "GO:0070099" ]
[ "GO:0065007", "positively_regulates GO:0070098" ]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0070103
70,103
regulation of interleukin-6-mediated signaling pathway
biological_process
Any process that modulates the rate, frequency or extent of an interleukin-6-mediated signaling pathway.
[ "GOC:BHF", "GOC:mah" ]
null
[ "regulation of IL-6-mediated signaling pathway", "regulation of interleukin-6-mediated signalling pathway" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001959" ]
[ "regulates GO:0070102" ]
[ "regulates" ]
[ "GO:0070102" ]
[ "GO:0001959", "GO:0070102" ]
[ "GO:0065007", "regulates GO:0070102" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0070104
70,104
negative regulation of interleukin-6-mediated signaling pathway
biological_process
Any process that decreases the rate, frequency or extent of an interleukin-6-mediated signaling pathway.
[ "GOC:BHF", "GOC:mah" ]
null
[ "negative regulation of IL-6-mediated signaling pathway", "negative regulation of interleukin-6-mediated signalling pathway" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001960", "GO:0070103" ]
[ "negatively_regulates GO:0070102" ]
[ "negatively_regulates" ]
[ "GO:0070102" ]
[ "GO:0001960", "GO:0070102", "GO:0070103" ]
[ "GO:0065007", "negatively_regulates GO:0070102" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0070105
70,105
positive regulation of interleukin-6-mediated signaling pathway
biological_process
Any process that increases the rate, frequency or extent of an interleukin-6-mediated signaling pathway.
[ "GOC:BHF", "GOC:mah" ]
null
[ "positive regulation of IL-6-mediated signaling pathway", "positive regulation of interleukin-6-mediated signalling pathway" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001961", "GO:0070103" ]
[ "positively_regulates GO:0070102" ]
[ "positively_regulates" ]
[ "GO:0070102" ]
[ "GO:0001961", "GO:0070102", "GO:0070103" ]
[ "GO:0065007", "positively_regulates GO:0070102" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0070106
70,106
interleukin-27-mediated signaling pathway
biological_process
The series of molecular signals initiated by interleukin-27 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
[ "GOC:add", "GOC:BHF", "GOC:mah", "GOC:signaling" ]
null
[ "IL-27-mediated signaling pathway", "IL27RA/IL6ST signaling pathway", "interleukin-27-mediated signalling pathway" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-9020956 \"Interleukin-27 signaling\"" ]
[ "GO:0019221" ]
[]
[]
[]
[ "GO:0019221" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0070107
70,107
regulation of interleukin-27-mediated signaling pathway
biological_process
Any process that modulates the rate, frequency or extent of an interleukin-27-mediated signaling pathway.
[ "GOC:BHF", "GOC:mah" ]
null
[ "regulation of IL-27-mediated signaling pathway", "regulation of IL27RA/IL6ST signaling pathway", "regulation of interleukin-27-mediated signalling pathway" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001959" ]
[ "regulates GO:0070106" ]
[ "regulates" ]
[ "GO:0070106" ]
[ "GO:0001959", "GO:0070106" ]
[ "GO:0065007", "regulates GO:0070106" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0070108
70,108
negative regulation of interleukin-27-mediated signaling pathway
biological_process
Any process that decreases the rate, frequency or extent of an interleukin-27-mediated signaling pathway.
[ "GOC:BHF", "GOC:mah" ]
null
[ "negative regulation of IL-27-mediated signaling pathway", "negative regulation of IL27RA/IL6ST signaling pathway", "negative regulation of interleukin-27-mediated signalling pathway" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001960", "GO:0070107" ]
[ "negatively_regulates GO:0070106" ]
[ "negatively_regulates" ]
[ "GO:0070106" ]
[ "GO:0001960", "GO:0070106", "GO:0070107" ]
[ "GO:0065007", "negatively_regulates GO:0070106" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0070109
70,109
positive regulation of interleukin-27-mediated signaling pathway
biological_process
Any process that increases the rate, frequency or extent of an interleukin-27-mediated signaling pathway.
[ "GOC:BHF", "GOC:mah" ]
null
[ "positive regulation of IL-27-mediated signaling pathway", "positive regulation of IL27RA/IL6ST signaling pathway", "positive regulation of interleukin-27-mediated signalling pathway" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001961", "GO:0070107" ]
[ "positively_regulates GO:0070106" ]
[ "positively_regulates" ]
[ "GO:0070106" ]
[ "GO:0001961", "GO:0070106", "GO:0070107" ]
[ "GO:0065007", "positively_regulates GO:0070106" ]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0070110
70,110
ciliary neurotrophic factor receptor complex
cellular_component
A protein complex that acts as a receptor for the cytokine ciliary neurotrophic factor (CNTF). In humans the receptor complex is a hexamer composed of two molecules each of CNTF and CNTFR and one molecule each of gp130 and LIFR.
[ "GOC:BHF", "GOC:mah", "GOC:rl", "PMID:12707266" ]
null
[]
[]
[]
[]
[]
[ "GO:0098802" ]
[]
[]
[]
[ "GO:0098802" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0070111
70,111
organellar chromatophore
cellular_component
A bacteroid-containing symbiosome in which the bacterial component is a genetically highly reduced cyanobacterium that is photosynthetically active and incapable of an independent existence outside its host. The chromatophore functions as a photosynthetic organelle, and has been found and characterized in the amoeba Pa...
[ "GOC:expert_mm", "PMID:18356055" ]
null
[ "Paulinella-type chromatophore" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0043660" ]
[]
[]
[]
[ "GO:0043660" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0070112
70,112
organellar chromatophore membrane
cellular_component
Either of the lipid bilayers that surround an organellar chromatophore.
[ "GOC:mah" ]
null
[ "Paulinella-type chromatophore membrane" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0030659" ]
[ "part_of GO:0070111" ]
[ "part_of" ]
[ "GO:0070111" ]
[ "GO:0030659", "GO:0070111" ]
[ "GO:0016020", "part_of GO:0070111" ]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0070113
70,113
organellar chromatophore inner membrane
cellular_component
The inner, i.e. lumen-facing, of the two lipid bilayers surrounding an organellar chromatophore.
[ "GOC:mah" ]
null
[ "Paulinella-type chromatophore inner membrane" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0070112" ]
[]
[]
[]
[ "GO:0070112" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0070114
70,114
organellar chromatophore outer membrane
cellular_component
The outer, i.e. cytoplasm-facing, of the two lipid bilayers surrounding an organellar chromatophore.
[ "GOC:mah" ]
null
[ "Paulinella-type chromatophore outer membrane" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0043661", "GO:0070112" ]
[]
[]
[]
[ "GO:0043661", "GO:0070112" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0070115
70,115
organellar chromatophore intermembrane space
cellular_component
The region between the inner and outer lipid bilayers that surround an organellar chromatophore.
[ "GOC:mah" ]
null
[ "Paulinella-type chromatophore intermembrane space" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0070111" ]
[ "part_of" ]
[ "GO:0070111" ]
[ "GO:0070111", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0070116
70,116
organellar chromatophore thylakoid
cellular_component
A thylakoid located in an organellar chromatophore.
[ "GOC:mah" ]
null
[ "Paulinella-type chromatophore thylakoid" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0009579" ]
[ "part_of GO:0070111" ]
[ "part_of" ]
[ "GO:0070111" ]
[ "GO:0009579", "GO:0070111" ]
[ "GO:0009579", "part_of GO:0070111" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0070118
70,118
organellar chromatophore thylakoid membrane
cellular_component
The lipid bilayer membrane of any thylakoid within an organellar chromatophore.
[ "GOC:mah" ]
null
[ "Paulinella-type chromatophore thylakoid membrane" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0042651", "GO:0070112" ]
[ "part_of GO:0070116" ]
[ "part_of" ]
[ "GO:0070116" ]
[ "GO:0042651", "GO:0070112", "GO:0070116" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0070119
70,119
ciliary neurotrophic factor binding
molecular_function
Binding to the cytokine ciliary neurotrophic factor.
[ "GOC:BHF", "GOC:mah" ]
null
[ "CNTF binding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0019955" ]
[]
[]
[]
[ "GO:0019955" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0070120
70,120
ciliary neurotrophic factor-mediated signaling pathway
biological_process
The series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
[ "GOC:BHF", "GOC:mah" ]
null
[ "ciliary neurotrophic factor-mediated signalling pathway", "CNTF-mediated signaling pathway" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0019221" ]
[]
[]
[]
[ "GO:0019221" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0070121
70,121
Kupffer's vesicle development
biological_process
The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.
[ "GOC:dgh" ]
null
[ "KV development" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0048856" ]
[]
[]
[]
[ "GO:0048856" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0070123
70,123
transforming growth factor beta receptor activity, type III
molecular_function
Combining with transforming growth factor beta to initiate a change in cell activity; facilitates ligand binding to type I and type II TGF-beta receptors.
[ "GOC:BHF", "GOC:mah", "PMID:9759503" ]
null
[ "betaglycan", "endoglin", "transforming growth factor beta ligand binding to type III receptor", "type III TGF-beta receptor activity", "type III TGFbeta receptor activity", "type III transforming growth factor beta receptor activity" ]
[ "NARROW", "NARROW", "RELATED", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0005024" ]
[]
[]
[]
[ "GO:0005024" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.7.11.30", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
null
null
false
true
5
GO:0070124
70,124
mitochondrial translational initiation
biological_process
The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
[ "GOC:mah" ]
null
[ "mitochondrial translation initiation" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-5368286 \"Mitochondrial translation initiation\"" ]
[ "GO:0006413" ]
[ "occurs_in GO:0005739", "part_of GO:0032543" ]
[ "occurs_in", "part_of" ]
[ "GO:0005739", "GO:0032543" ]
[ "GO:0005739", "GO:0006413", "GO:0032543" ]
[ "GO:0006413", "occurs_in GO:0005739" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0070125
70,125
mitochondrial translational elongation
biological_process
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
[ "GOC:mah" ]
null
[ "mitochondrial translation elongation" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-5389840 \"Mitochondrial translation elongation\"" ]
[ "GO:0006414" ]
[ "occurs_in GO:0005739", "part_of GO:0032543" ]
[ "occurs_in", "part_of" ]
[ "GO:0005739", "GO:0032543" ]
[ "GO:0005739", "GO:0006414", "GO:0032543" ]
[ "GO:0006414", "occurs_in GO:0005739" ]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0070126
70,126
mitochondrial translational termination
biological_process
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).
[ "GOC:mah", "http://mitogenome.org/index.php/Genetic_Code_of_mitochondria" ]
null
[ "mitochondrial translation termination" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-5419276 \"Mitochondrial translation termination\"", "Reactome:R-HSA-9937383 \"Mitochondrial ribosome-associated quality control\"" ]
[ "GO:0006415" ]
[ "occurs_in GO:0005739", "part_of GO:0032543" ]
[ "occurs_in", "part_of" ]
[ "GO:0005739", "GO:0032543" ]
[ "GO:0005739", "GO:0006415", "GO:0032543" ]
[ "GO:0006415", "occurs_in GO:0005739" ]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0070127
70,127
tRNA aminoacylation for mitochondrial protein translation
biological_process
The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0000959", "GO:0006418" ]
[ "part_of GO:0032543" ]
[ "part_of" ]
[ "GO:0032543" ]
[ "GO:0000959", "GO:0006418", "GO:0032543" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0070129
70,129
regulation of mitochondrial translation
biological_process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
[ "GOC:mah" ]
null
[ "regulation of mitochondrial protein anabolism", "regulation of mitochondrial protein biosynthesis", "regulation of mitochondrial protein formation", "regulation of mitochondrial protein synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006417", "GO:0062125" ]
[ "regulates GO:0032543" ]
[ "regulates" ]
[ "GO:0032543" ]
[ "GO:0006417", "GO:0032543", "GO:0062125" ]
[ "GO:0065007", "regulates GO:0032543" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0070130
70,130
negative regulation of mitochondrial translation
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
[ "GOC:mah" ]
null
[ "negative regulation of mitochondrial protein anabolism", "negative regulation of mitochondrial protein biosynthesis", "negative regulation of mitochondrial protein formation", "negative regulation of mitochondrial protein synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0017148", "GO:0070129" ]
[ "negatively_regulates GO:0032543" ]
[ "negatively_regulates" ]
[ "GO:0032543" ]
[ "GO:0017148", "GO:0032543", "GO:0070129" ]
[ "GO:0065007", "negatively_regulates GO:0032543" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0070131
70,131
positive regulation of mitochondrial translation
biological_process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
[ "GOC:mah" ]
null
[ "positive regulation of mitochondrial protein anabolism", "positive regulation of mitochondrial protein biosynthesis", "positive regulation of mitochondrial protein formation", "positive regulation of mitochondrial protein synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0045727", "GO:0070129" ]
[ "positively_regulates GO:0032543" ]
[ "positively_regulates" ]
[ "GO:0032543" ]
[ "GO:0032543", "GO:0045727", "GO:0070129" ]
[ "GO:0065007", "positively_regulates GO:0032543" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0070132
70,132
regulation of mitochondrial translational initiation
biological_process
Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
[ "GOC:mah" ]
null
[ "regulation of mitochondrial translation initiation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006446", "GO:0070129" ]
[ "regulates GO:0070124" ]
[ "regulates" ]
[ "GO:0070124" ]
[ "GO:0006446", "GO:0070124", "GO:0070129" ]
[ "GO:0065007", "regulates GO:0070124" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0070133
70,133
negative regulation of mitochondrial translational initiation
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
[ "GOC:mah" ]
null
[ "negative regulation of mitochondrial translation initiation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0045947", "GO:0070132" ]
[ "negatively_regulates GO:0070124" ]
[ "negatively_regulates" ]
[ "GO:0070124" ]
[ "GO:0045947", "GO:0070124", "GO:0070132" ]
[ "GO:0065007", "negatively_regulates GO:0070124" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0070134
70,134
positive regulation of mitochondrial translational initiation
biological_process
Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
[ "GOC:mah" ]
null
[ "positive regulation of mitochondrial translation initiation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0045948", "GO:0070131", "GO:0070132" ]
[ "positively_regulates GO:0070124" ]
[ "positively_regulates" ]
[ "GO:0070124" ]
[ "GO:0045948", "GO:0070124", "GO:0070131", "GO:0070132" ]
[ "GO:0065007", "positively_regulates GO:0070124" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0070135
70,135
beta-1,2-oligomannoside metabolic process
biological_process
The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.
[ "GOC:mah", "PMID:18234669" ]
null
[ "beta-1,2-oligomannoside metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0010412" ]
[]
[]
[]
[ "GO:0010412" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0070136
70,136
beta-1,2-oligomannoside biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.
[ "GOC:mah", "PMID:18234669" ]
null
[ "beta-1,2-oligomannoside anabolism", "beta-1,2-oligomannoside biosynthesis", "beta-1,2-oligomannoside formation", "beta-1,2-oligomannoside synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0046354", "GO:0051278", "GO:0070135" ]
[]
[]
[]
[ "GO:0046354", "GO:0051278", "GO:0070135" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0070137
70,137
ubiquitin-like protein-specific endopeptidase activity
molecular_function
Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO).
[ "GOC:mah" ]
null
[ "small conjugating protein-specific endopeptidase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0004197", "GO:0019783" ]
[]
[]
[]
[ "GO:0004197", "GO:0019783" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7