go_id string | go_numeric_id int64 | name string | namespace string | definition string | definition_xrefs list | comment string | synonyms list | synonym_scopes list | alt_ids list | subsets list | xrefs list | is_a_ids list | relationship_edges list | relationship_types list | relationship_target_ids list | parent_ids list | intersection_of list | union_of list | disjoint_from list | replaced_by list | consider list | property_values list | created_by string | creation_date string | is_obsolete bool | in_go_basic bool | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GO:0070025 | 70,025 | carbon monoxide binding | molecular_function | Binding to carbon monoxide (CO). | [
"GOC:ecd"
] | null | [
"CO binding"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0036094"
] | [] | [] | [] | [
"GO:0036094"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21211\" xsd:anyURI"
] | null | null | false | true | 3 |
GO:0070027 | 70,027 | carbon monoxide sensor activity | molecular_function | Binding to and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO). | [
"GOC:ecd"
] | null | [
"carbon monoxide sensing activity"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0140299"
] | [
"has_part GO:0070025"
] | [
"has_part"
] | [
"GO:0070025"
] | [
"GO:0070025",
"GO:0140299"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25267\" xsd:anyURI"
] | null | null | false | true | 5 |
GO:0070028 | 70,028 | obsolete regulation of transcription by carbon monoxide | biological_process | OBSOLETE. Any process involving carbon monoxide that modulates the frequency, rate or extent of transcription. | [
"GOC:ecd"
] | This term was obsoleted because it represents a GO-CAM model. | [
"regulation of transcription by CO"
] | [
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0006357"
] | [] | null | null | true | true | 7 |
GO:0070029 | 70,029 | alphav-beta3 integrin-osteopontin complex | cellular_component | A protein complex that consists of an alphav-beta3 integrin complex bound to osteopontin. | [
"PMID:7532190"
] | null | [
"ITGAV-ITGB3-SPP1 complex"
] | [
"NARROW"
] | [] | [] | [] | [
"GO:0098797"
] | [] | [] | [] | [
"GO:0098797"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0070030 | 70,030 | alphav-beta1 integrin-osteopontin complex | cellular_component | A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin. | [
"PMID:7592829"
] | null | [
"ITGAV-ITGB1-SPP1 complex"
] | [
"NARROW"
] | [] | [] | [] | [
"GO:0098797"
] | [] | [] | [] | [
"GO:0098797"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0070031 | 70,031 | alphav-beta5 integrin-osteopontin complex | cellular_component | A protein complex that consists of an alphav-beta5 integrin complex bound to osteopontin. | [
"PMID:7592829"
] | null | [
"ITGAV-ITGB5-SPP1 complex"
] | [
"NARROW"
] | [] | [] | [] | [
"GO:0098797"
] | [] | [] | [] | [
"GO:0098797"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0070033 | 70,033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex | cellular_component | A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin II (or orthologs thereof). | [
"PMID:7553862"
] | null | [
"SNARE complex (Vamp2, Snap25, Stx1a, Cplx2)",
"Vamp2-Snap25-Stx1a-Cplx2 complex"
] | [
"NARROW",
"NARROW"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0070034 | 70,034 | telomerase RNA binding | molecular_function | Binding to the telomerase RNA template. | [
"GOC:krc",
"PMID:16884717"
] | null | [
"TERC binding"
] | [
"RELATED"
] | [] | [] | [] | [
"GO:0003723"
] | [] | [] | [] | [
"GO:0003723"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0070035 | 70,035 | obsolete purine NTP-dependent helicase activity | molecular_function | OBSOLETE. Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix. | [
"GOC:mah"
] | The reason for obsoletion is that helicases only and always use ATP (although under very specific experimental conditions GTP can perhaps be used; this is not the case in vivo), therefore this term was an unnecessary grouping term. | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | null | null | true | true | 2 |
GO:0070036 | 70,036 | obsolete GTP-dependent helicase activity | molecular_function | OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate, to drive the unwinding of a DNA or RNA helix. | [
"GOC:mah"
] | The reason for obsoletion is that helicases only and always use ATP (although under very specific experimental conditions GTP can perhaps be used; this is not the case in vivo). | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | null | null | true | true | 4 |
GO:0070037 | 70,037 | rRNA (pseudouridine) methyltransferase activity | molecular_function | Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule. | [
"GOC:imk",
"GOC:mah"
] | null | [] | [] | [] | [] | [
"Reactome:R-HSA-6790906 \"EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248\""
] | [
"GO:0008649"
] | [] | [] | [] | [
"GO:0008649"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0070038 | 70,038 | rRNA (pseudouridine-N3-)-methyltransferase activity | molecular_function | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine. | [
"GOC:imk",
"GOC:mah"
] | null | [] | [] | [] | [] | [] | [
"GO:0070037"
] | [] | [] | [] | [
"GO:0070037"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0070039 | 70,039 | rRNA (guanosine-2'-O-ribose)-methyltransferase activity | molecular_function | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine. | [
"GOC:imk",
"GOC:mah"
] | null | [
"rRNA (guanosine-2'-O-)-methyltransferase activity"
] | [
"EXACT"
] | [] | [] | [
"Reactome:R-HSA-6793096 \"MRM3 (RNMTL1) methylates guanosine-1370 of 16S rRNA yielding 2'-O-methylguanosine-1370\"",
"Reactome:R-HSA-6793122 \"MRM1 methylates guanosine-1145 of 16S rRNA yielding 2'-O-methylguanosine-1145\""
] | [
"GO:0016435",
"GO:0062105"
] | [
"part_of GO:0000451"
] | [
"part_of"
] | [
"GO:0000451"
] | [
"GO:0000451",
"GO:0016435",
"GO:0062105"
] | [] | [] | [] | [] | [] | [
"skos:broadMatch RHEA:58956",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI"
] | null | null | false | true | 8 |
GO:0070040 | 70,040 | rRNA (adenine(2503)-C2-)-methyltransferase activity | molecular_function | Catalysis of the reaction: adenosine2503 in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine2503 in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine. | [
"GOC:imk",
"PMID:20007606",
"PMID:20184321",
"PMID:21368151",
"PMID:21415317",
"PMID:21527678",
"RHEA:42916"
] | null | [
"rRNA (adenine-C2-)-methyltransferase activity"
] | [
"BROAD"
] | [] | [] | [
"MetaCyc:RXN-11586",
"RHEA:42916"
] | [
"GO:0008169",
"GO:0016433"
] | [] | [] | [] | [
"GO:0008169",
"GO:0016433"
] | [] | [] | [] | [] | [] | [
"skos:broadMatch EC:2.1.1.192",
"skos:exactMatch RHEA:42916",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26114\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28183\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-onto... | null | null | false | true | 9 |
GO:0070041 | 70,041 | rRNA (uridine-C5-)-methyltransferase activity | molecular_function | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine. | [
"GOC:imk",
"GOC:mah"
] | null | [] | [] | [] | [] | [] | [
"GO:0008169",
"GO:0016436"
] | [] | [] | [] | [
"GO:0008169",
"GO:0016436"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0070042 | 70,042 | rRNA (uridine-N3-)-methyltransferase activity | molecular_function | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine. | [
"GOC:imk",
"GOC:mah"
] | null | [] | [] | [] | [] | [] | [
"GO:0008170",
"GO:0016436"
] | [] | [] | [] | [
"GO:0008170",
"GO:0016436"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0070043 | 70,043 | rRNA (guanine-N7-)-methyltransferase activity | molecular_function | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine. | [
"GOC:imk",
"GOC:mah"
] | null | [] | [] | [] | [] | [
"Reactome:R-HSA-6790982 \"WBSCR22:TRMT112 methylates guanosine-1639 of 18S rRNA yielding 7-methylguanosine-1639\""
] | [
"GO:0008170",
"GO:0016435"
] | [
"part_of GO:0070476"
] | [
"part_of"
] | [
"GO:0070476"
] | [
"GO:0008170",
"GO:0016435",
"GO:0070476"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0070044 | 70,044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex | cellular_component | A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 1a (or orthologs thereof). | [
"PMID:10336434"
] | null | [
"Snap25-Stx1a-Vamp2 complex",
"SNARE complex (Snap25, Stx1a, Vamp2)",
"SNARE complex (Stx1a, SNAP25, VAMP)",
"Stx1a-SNAP25-VAMP complex"
] | [
"NARROW",
"NARROW",
"NARROW",
"NARROW"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0070045 | 70,045 | synaptobrevin 2-SNAP-25-syntaxin-2 complex | cellular_component | A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 2 (or orthologs thereof). | [
"PMID:10336434"
] | null | [
"SNARE complex (Stx2, Snap25, Vamp2)",
"Stx2-Snap25-Vamp2 complex"
] | [
"NARROW",
"NARROW"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0070046 | 70,046 | synaptobrevin 2-SNAP-25-syntaxin-3 complex | cellular_component | A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 3 (or orthologs thereof). | [
"PMID:10336434"
] | null | [
"SNARE complex (Stx3, Snap25, Vamp2)",
"Stx3-Snap25-Vamp2 complex"
] | [
"NARROW",
"NARROW"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0070047 | 70,047 | synaptobrevin 2-SNAP-25-syntaxin-4 complex | cellular_component | A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 4 (or orthologs thereof). | [
"PMID:10336434"
] | null | [
"SNARE complex (Stx4, Snap25, Vamp2)",
"Stx4-Snap25-Vamp2 complex"
] | [
"NARROW",
"NARROW"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0070050 | 70,050 | neuron cellular homeostasis | biological_process | The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state. | [
"GOC:BHF",
"GOC:mah"
] | null | [
"neuron maintenance"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0019725"
] | [] | [] | [] | [
"GO:0019725"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24218\" xsd:anyURI"
] | null | null | false | true | 9 |
GO:0070051 | 70,051 | fibrinogen binding | molecular_function | Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade. | [
"GOC:BHF",
"GOC:mah",
"GOC:vk"
] | null | [] | [] | [] | [] | [] | [
"GO:0044877"
] | [] | [] | [] | [
"GO:0044877"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0070052 | 70,052 | collagen V binding | molecular_function | Binding to a type V collagen trimer. | [
"GOC:BHF",
"GOC:mah"
] | null | [] | [] | [] | [] | [] | [
"GO:0005518"
] | [] | [] | [] | [
"GO:0005518"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0070053 | 70,053 | thrombospondin receptor activity | molecular_function | Combining with thrombospondin and transmitting the signal to initiate a change in cell activity. | [
"GOC:BHF",
"GOC:signaling",
"GOC:vk"
] | null | [] | [] | [] | [] | [] | [
"GO:0038023"
] | [] | [] | [] | [
"GO:0038023"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0070054 | 70,054 | mRNA splicing, via endonucleolytic cleavage and ligation | biological_process | Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons. | [
"GOC:krc",
"GOC:mah"
] | Note that while typically associated with tRNA splicing, splicing via endonucleolytic cleavages and subsequent ligation of the free exon ends is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis. | [
"cytosolic mRNA splicing"
] | [
"RELATED"
] | [
"GO:0061012"
] | [] | [] | [
"GO:0000394",
"GO:0006397"
] | [] | [] | [] | [
"GO:0000394",
"GO:0006397"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0070055 | 70,055 | obsolete mRNA endonucleolytic cleavage involved in unfolded protein response | biological_process | OBSOLETE. The endonucleolytic cleavage of a mRNA containing an HAC1-type intron at the 5' and 3' splice sites. The cleavage step is part of unconventional mRNA splicing, and contributes to the endoplasmic reticulum unfolded protein response. | [
"GOC:bf",
"GOC:krc",
"GOC:mah",
"PMID:10357823"
] | The reason for obsoletion is that this process represents a single step (molecular function) of the IRE1-mediated unfolded protein response (GO:0036498). | [
"ERN1-mediated XBP-1 mRNA cleavage",
"HAC1 mRNA cleavage",
"HAC1-type intron splice site recognition and cleavage",
"IRE1-mediated XBP-1 mRNA cleavage",
"XBP1 mRNA cleavage"
] | [
"RELATED",
"NARROW",
"NARROW",
"NARROW",
"NARROW"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0036498"
] | [] | null | null | true | true | 9 |
GO:0070056 | 70,056 | prospore membrane leading edge | cellular_component | The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization. | [
"GOC:mah",
"PMID:14702385"
] | null | [
"forespore membrane leading edge"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0016020"
] | [
"part_of GO:0005628"
] | [
"part_of"
] | [
"GO:0005628"
] | [
"GO:0005628",
"GO:0016020"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0070057 | 70,057 | prospore membrane spindle pole body attachment site | cellular_component | The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus. | [
"GOC:mah",
"PMID:14702385"
] | null | [
"forespore membrane SPB attachment site",
"forespore membrane spindle pole body attachment site",
"prospore membrane SPB attachment site"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0110165"
] | [
"part_of GO:0005628"
] | [
"part_of"
] | [
"GO:0005628"
] | [
"GO:0005628",
"GO:0110165"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0070058 | 70,058 | tRNA gene clustering | biological_process | The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. ce... | [
"GOC:jh",
"GOC:mah",
"PMID:18708579"
] | null | [] | [] | [] | [] | [] | [
"GO:0051276"
] | [] | [] | [] | [
"GO:0051276"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0070059 | 70,059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | biological_process | The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulati... | [
"GOC:mah",
"GOC:mtg_apoptosis",
"PMID:18701708"
] | null | [
"apoptosis in response to endoplasmic reticulum stress",
"apoptosis in response to ER stress",
"apoptosis triggered by ER stress",
"endoplasmic reticulum stress-induced apoptosis",
"ER stress-induced apoptosis",
"intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress"
] | [
"BROAD",
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0034976",
"GO:0097193"
] | [] | [] | [] | [
"GO:0034976",
"GO:0097193"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0070060 | 70,060 | 'de novo' actin filament nucleation | biological_process | The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament. | [
"GOC:mah",
"PMID:17477841"
] | null | [
"formin-mediated actin filament nucleation",
"unbranched actin filament nucleation"
] | [
"NARROW",
"RELATED"
] | [] | [] | [] | [
"GO:0045010"
] | [] | [] | [] | [
"GO:0045010"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0070061 | 70,061 | fructose binding | molecular_function | Binding to the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose. | [
"CHEBI:28757",
"GOC:BHF",
"GOC:mah"
] | null | [] | [] | [] | [] | [] | [
"GO:0048029"
] | [] | [] | [] | [
"GO:0048029"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0070062 | 70,062 | extracellular exosome | cellular_component | A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. | [
"GOC:BHF",
"GOC:mah",
"GOC:vesicles",
"PMID:15908444",
"PMID:17641064",
"PMID:19442504",
"PMID:19498381",
"PMID:22418571",
"PMID:24009894"
] | null | [
"exosome",
"extracellular vesicular exosome"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:1903561"
] | [] | [] | [] | [
"GO:1903561"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0070063 | 70,063 | RNA polymerase binding | molecular_function | Binding to an RNA polymerase molecule or complex. | [
"GOC:BHF",
"GOC:mah",
"GOC:txnOH"
] | null | [] | [] | [] | [] | [] | [
"GO:0019899"
] | [] | [] | [] | [
"GO:0019899"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0070065 | 70,065 | cellubrevin-VAMP4-syntaxin-16 complex | cellular_component | A SNARE complex that contains cellubrevin (VAMP3), VAMP4, and syntaxin 16 (or orthologs thereof). | [
"PMID:11839770"
] | null | [
"SNARE complex (Vamp3, Vamp4, Stx16)",
"Vamp3-Vamp4-Stx16 complex"
] | [
"NARROW",
"NARROW"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0070066 | 70,066 | cellubrevin-VAMP4-endobrevin-syntaxin-6 complex | cellular_component | A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof). | [
"PMID:11839770"
] | null | [
"SNARE complex (Vamp3, Vamp4, Vam8, Stx6)",
"Vamp3-Vamp4-Vam8-Stx6 complex"
] | [
"NARROW",
"NARROW"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0070067 | 70,067 | syntaxin-6-syntaxin-16-Vti1a complex | cellular_component | A SNARE complex that contains syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof). | [
"PMID:11839770"
] | null | [] | [] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0070068 | 70,068 | VAMP4-syntaxin-6-syntaxin-16-Vti1a complex | cellular_component | A SNARE complex that contains VAMP4, syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof). | [
"PMID:11839770"
] | null | [
"SNARE complex (Vamp4, Stx6, Stx16, Vti1a)",
"Vamp4-Stx6-Stx16-Vti1a complex"
] | [
"NARROW",
"RELATED"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [
"GO:0031201"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0070070 | 70,070 | proton-transporting V-type ATPase complex assembly | biological_process | The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. | [
"GOC:mah"
] | null | [
"V-ATPase assembly",
"V-ATPase complex assembly"
] | [
"RELATED",
"RELATED"
] | [] | [] | [] | [
"GO:0070071"
] | [] | [] | [] | [
"GO:0070071"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0070071 | 70,071 | proton-transporting two-sector ATPase complex assembly | biological_process | The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. | [
"GOC:mah"
] | null | [] | [] | [] | [] | [] | [
"GO:0065003"
] | [] | [] | [] | [
"GO:0065003"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0070072 | 70,072 | vacuolar proton-transporting V-type ATPase complex assembly | biological_process | The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane. | [
"GOC:BHF",
"GOC:mah"
] | null | [
"V-ATPase assembly",
"V-ATPase complex assembly"
] | [
"BROAD",
"BROAD"
] | [] | [] | [] | [
"GO:0070070"
] | [] | [] | [] | [
"GO:0070070"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0070073 | 70,073 | clustering of voltage-gated calcium channels | biological_process | The process in which voltage-gated calcium channels become localized together in high densities. | [
"GOC:BHF",
"GOC:sart",
"PMID:18385325"
] | null | [
"clustering of voltage gated calcium channels",
"clustering of voltage-dependent calcium channels",
"voltage-gated calcium channel clustering"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0045161"
] | [] | [] | [] | [
"GO:0045161"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0070074 | 70,074 | mononeme | cellular_component | A secretory organelle that forms part of the apical complex; a small, threadlike structure located is close proximity to the subpellicular microtubules. Its contents include a rhomboid protease (PfROM1 in Plasmodium falciparum) that moves from the lateral asymmetric localization to the merozoite apical pole and the pos... | [
"GOC:BHF",
"PMID:18048320"
] | null | [] | [] | [] | [] | [] | [
"GO:0043231"
] | [
"part_of GO:0020007"
] | [
"part_of"
] | [
"GO:0020007"
] | [
"GO:0020007",
"GO:0043231"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0070075 | 70,075 | tear secretion | biological_process | The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium. | [
"GOC:rph"
] | null | [] | [] | [] | [] | [] | [
"GO:0007589",
"GO:0032941"
] | [] | [] | [] | [
"GO:0007589",
"GO:0032941"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0070076 | 70,076 | obsolete histone lysine demethylation | biological_process | OBSOLETE. The modification of a histone by the removal of a methyl group from a lysine residue. | [
"GOC:mah"
] | This term was obsoleted because it represents a molecular function. | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI"
] | null | null | true | true | 6 |
GO:0070077 | 70,077 | obsolete histone arginine demethylation | biological_process | OBSOLETE. The modification of a histone by the removal of a methyl group from an arginine residue. | [
"GOC:mah"
] | This term was obsoleted because it represents a molecular function. | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0032452"
] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24261\" xsd:anyURI"
] | null | null | true | true | 4 |
GO:0070078 | 70,078 | obsolete histone H3-R2 demethylation | biological_process | OBSOLETE. The modification of histone H3 by the removal of a methyl group from arginine at position 2 of the histone. | [
"GOC:BHF",
"GOC:vk"
] | This term was obsoleted because it represents a molecular function. | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI"
] | null | null | true | true | 8 |
GO:0070079 | 70,079 | obsolete histone H4-R3 demethylation | biological_process | OBSOLETE. The modification of histone H4 by the removal of a methyl group from arginine at position 3 of the histone. | [
"GOC:BHF",
"GOC:vk"
] | This term was obsoleted because it represents a molecular function. | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI"
] | null | null | true | true | 3 |
GO:0070080 | 70,080 | titin Z domain binding | molecular_function | Binding to a titin Z protein domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34. | [
"GOC:mah",
"InterPro:IPR015129"
] | null | [
"Z repeat domain binding"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0019904"
] | [] | [] | [] | [
"GO:0019904"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0070081 | 70,081 | clathrin-sculpted monoamine transport vesicle | cellular_component | A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing monoamines. | [
"GOC:mg2"
] | null | [
"clathrin sculpted monoamine constitutive secretory pathway transport vesicle",
"clathrin sculpted monoamine transport vesicle"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0030133",
"GO:0060198"
] | [] | [] | [] | [
"GO:0030133",
"GO:0060198"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0070082 | 70,082 | clathrin-sculpted monoamine transport vesicle lumen | cellular_component | The volume enclosed by the membrane of the clathrin-sculpted monoamine transport vesicle. | [
"GOC:mg2"
] | null | [
"clathrin sculpted monoamine constitutive secretory pathway transport vesicle lumen",
"clathrin sculpted monoamine transport vesicle lumen"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0060205"
] | [
"part_of GO:0070081"
] | [
"part_of"
] | [
"GO:0070081"
] | [
"GO:0060205",
"GO:0070081"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0070083 | 70,083 | clathrin-sculpted monoamine transport vesicle membrane | cellular_component | The lipid bilayer surrounding a clathrin-sculpted monoamine transport vesicle. | [
"GOC:mg2"
] | null | [
"clathrin sculpted monoamine constitutive secretory pathway transport vesicle membrane",
"clathrin sculpted monoamine transport vesicle membrane"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0030658",
"GO:0030665"
] | [
"part_of GO:0070081"
] | [
"part_of"
] | [
"GO:0070081"
] | [
"GO:0030658",
"GO:0030665",
"GO:0070081"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0070084 | 70,084 | obsolete protein initiator methionine removal | biological_process | OBSOLETE. The protein modification process in which the translation-initiating methionine or formylmethionine residue is removed from a protein. | [
"GOC:imk",
"GOC:mah"
] | The reason for obsoletion is that this term represents a molecular function. | [
"removal of initiator methionine from protein"
] | [
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25210\" xsd:anyURI"
] | null | null | true | true | 4 |
GO:0070085 | 70,085 | obsolete glycosylation | biological_process | OBSOLETE. The covalent attachment and further modification of carbohydrate residues to a substrate molecule. | [
"GOC:hjd",
"GOC:mah"
] | The reason for obsoletion is that this term represents a molecular function. | [] | [] | [] | [] | [
"Wikipedia:Glycosylation"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30371\" xsd:anyURI"
] | null | null | true | true | 1 |
GO:0070087 | 70,087 | chromo shadow domain binding | molecular_function | Binding to a chromo shadow domain, a protein domain that is distantly related, and found in association with, the chromo domain. | [
"GOC:BHF",
"GOC:vk",
"InterPro:IPR008251",
"PMID:7667093"
] | null | [
"chromoshadow domain binding"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0019904"
] | [] | [] | [] | [
"GO:0019904"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0070088 | 70,088 | polyhydroxyalkanoate granule | cellular_component | An inclusion body located in the cytoplasm of prokaryotes that consists of polyhydroxyalkanoate (PHA) molecules and associated proteins, surrounded by a phospholipid monolayer; the proteins include PHA synthase, PHA depolymerase and 3HB-oligomer hydroxylase, phasins (PhaPs), which are thought to be the major structural... | [
"GOC:mah",
"PMID:15762612"
] | null | [
"carbonosome",
"PHA granule",
"PHB granule"
] | [
"BROAD",
"EXACT",
"NARROW"
] | [] | [] | [] | [
"GO:0016234",
"GO:0043231"
] | [
"part_of GO:0005737"
] | [
"part_of"
] | [
"GO:0005737"
] | [
"GO:0005737",
"GO:0016234",
"GO:0043231"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24423\" xsd:anyURI"
] | null | null | false | true | 2 |
GO:0070089 | 70,089 | chloride-activated potassium channel activity | molecular_function | Enables the transmembrane transfer of a potassium cation by a channel that opens when a chloride ion has been bound by the channel complex or one of its constituent parts. | [
"GOC:kmv",
"GOC:mtg_transport"
] | null | [] | [] | [] | [] | [] | [
"GO:0005267",
"GO:0022839",
"GO:0099094"
] | [] | [] | [] | [
"GO:0005267",
"GO:0022839",
"GO:0099094"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24605\" xsd:anyURI"
] | null | null | false | true | 5 |
GO:0070090 | 70,090 | metaphase plate | cellular_component | The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division. | [
"GOC:mah"
] | null | [] | [] | [] | [] | [] | [
"GO:0005622"
] | [] | [] | [] | [
"GO:0005622"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0070091 | 70,091 | glucagon secretion | biological_process | The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans). | [
"GOC:BHF",
"GOC:rl"
] | null | [] | [] | [] | [] | [] | [
"GO:0030072"
] | [] | [] | [] | [
"GO:0030072"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0070092 | 70,092 | regulation of glucagon secretion | biological_process | Any process that modulates the frequency, rate or extent of the regulated release of glucagon. | [
"GOC:BHF",
"GOC:mah"
] | null | [] | [] | [] | [] | [] | [
"GO:0090276"
] | [
"regulates GO:0070091"
] | [
"regulates"
] | [
"GO:0070091"
] | [
"GO:0070091",
"GO:0090276"
] | [
"GO:0065007",
"regulates GO:0070091"
] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0070093 | 70,093 | negative regulation of glucagon secretion | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon. | [
"GOC:BHF",
"GOC:mah"
] | null | [
"down regulation of glucagon secretion",
"down-regulation of glucagon secretion",
"downregulation of glucagon secretion",
"inhibition of glucagon secretion"
] | [
"EXACT",
"EXACT",
"EXACT",
"NARROW"
] | [] | [] | [] | [
"GO:0070092",
"GO:0090278"
] | [
"negatively_regulates GO:0070091"
] | [
"negatively_regulates"
] | [
"GO:0070091"
] | [
"GO:0070091",
"GO:0070092",
"GO:0090278"
] | [
"GO:0065007",
"negatively_regulates GO:0070091"
] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0070094 | 70,094 | positive regulation of glucagon secretion | biological_process | Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon. | [
"GOC:BHF",
"GOC:mah"
] | null | [
"activation of glucagon secretion",
"stimulation of glucagon secretion",
"up regulation of glucagon secretion",
"up-regulation of glucagon secretion",
"upregulation of glucagon secretion"
] | [
"NARROW",
"NARROW",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0070092",
"GO:0090277"
] | [
"positively_regulates GO:0070091"
] | [
"positively_regulates"
] | [
"GO:0070091"
] | [
"GO:0070091",
"GO:0070092",
"GO:0090277"
] | [
"GO:0065007",
"positively_regulates GO:0070091"
] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0070095 | 70,095 | fructose-6-phosphate binding | molecular_function | Binding to fructose 6-phosphate. | [
"GOC:mah"
] | null | [
"D-fructose 6-phosphate binding",
"fructose 6-phosphate binding"
] | [
"NARROW",
"EXACT"
] | [] | [] | [] | [
"GO:0043168",
"GO:0097367"
] | [] | [] | [] | [
"GO:0043168",
"GO:0097367"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0070098 | 70,098 | chemokine-mediated signaling pathway | biological_process | The series of molecular signals initiated by a chemokine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. | [
"GOC:mah",
"GOC:signaling"
] | null | [
"chemokine-mediated signalling pathway"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0007186",
"GO:0019221"
] | [
"part_of GO:1990869"
] | [
"part_of"
] | [
"GO:1990869"
] | [
"GO:0007186",
"GO:0019221",
"GO:1990869"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26684\" xsd:anyURI"
] | null | null | false | true | 7 |
GO:0070099 | 70,099 | regulation of chemokine-mediated signaling pathway | biological_process | Any process that modulates the rate, frequency or extent of a chemokine-mediated signaling pathway. | [
"GOC:mah"
] | null | [
"regulation of chemokine-mediated signalling pathway"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0001959",
"GO:0008277"
] | [
"regulates GO:0070098"
] | [
"regulates"
] | [
"GO:0070098"
] | [
"GO:0001959",
"GO:0008277",
"GO:0070098"
] | [
"GO:0065007",
"regulates GO:0070098"
] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0070100 | 70,100 | negative regulation of chemokine-mediated signaling pathway | biological_process | Any process that decreases the rate, frequency or extent of a chemokine-mediated signaling pathway. | [
"GOC:mah"
] | null | [
"negative regulation of chemokine-mediated signalling pathway"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0001960",
"GO:0045744",
"GO:0070099"
] | [
"negatively_regulates GO:0070098"
] | [
"negatively_regulates"
] | [
"GO:0070098"
] | [
"GO:0001960",
"GO:0045744",
"GO:0070098",
"GO:0070099"
] | [
"GO:0065007",
"negatively_regulates GO:0070098"
] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0070101 | 70,101 | positive regulation of chemokine-mediated signaling pathway | biological_process | Any process that increases the rate, frequency or extent of a chemokine-mediated signaling pathway. | [
"GOC:mah"
] | null | [
"positive regulation of chemokine-mediated signalling pathway"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0001961",
"GO:0045745",
"GO:0070099"
] | [
"positively_regulates GO:0070098"
] | [
"positively_regulates"
] | [
"GO:0070098"
] | [
"GO:0001961",
"GO:0045745",
"GO:0070098",
"GO:0070099"
] | [
"GO:0065007",
"positively_regulates GO:0070098"
] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0070103 | 70,103 | regulation of interleukin-6-mediated signaling pathway | biological_process | Any process that modulates the rate, frequency or extent of an interleukin-6-mediated signaling pathway. | [
"GOC:BHF",
"GOC:mah"
] | null | [
"regulation of IL-6-mediated signaling pathway",
"regulation of interleukin-6-mediated signalling pathway"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0001959"
] | [
"regulates GO:0070102"
] | [
"regulates"
] | [
"GO:0070102"
] | [
"GO:0001959",
"GO:0070102"
] | [
"GO:0065007",
"regulates GO:0070102"
] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0070104 | 70,104 | negative regulation of interleukin-6-mediated signaling pathway | biological_process | Any process that decreases the rate, frequency or extent of an interleukin-6-mediated signaling pathway. | [
"GOC:BHF",
"GOC:mah"
] | null | [
"negative regulation of IL-6-mediated signaling pathway",
"negative regulation of interleukin-6-mediated signalling pathway"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0001960",
"GO:0070103"
] | [
"negatively_regulates GO:0070102"
] | [
"negatively_regulates"
] | [
"GO:0070102"
] | [
"GO:0001960",
"GO:0070102",
"GO:0070103"
] | [
"GO:0065007",
"negatively_regulates GO:0070102"
] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0070105 | 70,105 | positive regulation of interleukin-6-mediated signaling pathway | biological_process | Any process that increases the rate, frequency or extent of an interleukin-6-mediated signaling pathway. | [
"GOC:BHF",
"GOC:mah"
] | null | [
"positive regulation of IL-6-mediated signaling pathway",
"positive regulation of interleukin-6-mediated signalling pathway"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0001961",
"GO:0070103"
] | [
"positively_regulates GO:0070102"
] | [
"positively_regulates"
] | [
"GO:0070102"
] | [
"GO:0001961",
"GO:0070102",
"GO:0070103"
] | [
"GO:0065007",
"positively_regulates GO:0070102"
] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0070106 | 70,106 | interleukin-27-mediated signaling pathway | biological_process | The series of molecular signals initiated by interleukin-27 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. | [
"GOC:add",
"GOC:BHF",
"GOC:mah",
"GOC:signaling"
] | null | [
"IL-27-mediated signaling pathway",
"IL27RA/IL6ST signaling pathway",
"interleukin-27-mediated signalling pathway"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"Reactome:R-HSA-9020956 \"Interleukin-27 signaling\""
] | [
"GO:0019221"
] | [] | [] | [] | [
"GO:0019221"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0070107 | 70,107 | regulation of interleukin-27-mediated signaling pathway | biological_process | Any process that modulates the rate, frequency or extent of an interleukin-27-mediated signaling pathway. | [
"GOC:BHF",
"GOC:mah"
] | null | [
"regulation of IL-27-mediated signaling pathway",
"regulation of IL27RA/IL6ST signaling pathway",
"regulation of interleukin-27-mediated signalling pathway"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0001959"
] | [
"regulates GO:0070106"
] | [
"regulates"
] | [
"GO:0070106"
] | [
"GO:0001959",
"GO:0070106"
] | [
"GO:0065007",
"regulates GO:0070106"
] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0070108 | 70,108 | negative regulation of interleukin-27-mediated signaling pathway | biological_process | Any process that decreases the rate, frequency or extent of an interleukin-27-mediated signaling pathway. | [
"GOC:BHF",
"GOC:mah"
] | null | [
"negative regulation of IL-27-mediated signaling pathway",
"negative regulation of IL27RA/IL6ST signaling pathway",
"negative regulation of interleukin-27-mediated signalling pathway"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0001960",
"GO:0070107"
] | [
"negatively_regulates GO:0070106"
] | [
"negatively_regulates"
] | [
"GO:0070106"
] | [
"GO:0001960",
"GO:0070106",
"GO:0070107"
] | [
"GO:0065007",
"negatively_regulates GO:0070106"
] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0070109 | 70,109 | positive regulation of interleukin-27-mediated signaling pathway | biological_process | Any process that increases the rate, frequency or extent of an interleukin-27-mediated signaling pathway. | [
"GOC:BHF",
"GOC:mah"
] | null | [
"positive regulation of IL-27-mediated signaling pathway",
"positive regulation of IL27RA/IL6ST signaling pathway",
"positive regulation of interleukin-27-mediated signalling pathway"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0001961",
"GO:0070107"
] | [
"positively_regulates GO:0070106"
] | [
"positively_regulates"
] | [
"GO:0070106"
] | [
"GO:0001961",
"GO:0070106",
"GO:0070107"
] | [
"GO:0065007",
"positively_regulates GO:0070106"
] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0070110 | 70,110 | ciliary neurotrophic factor receptor complex | cellular_component | A protein complex that acts as a receptor for the cytokine ciliary neurotrophic factor (CNTF). In humans the receptor complex is a hexamer composed of two molecules each of CNTF and CNTFR and one molecule each of gp130 and LIFR. | [
"GOC:BHF",
"GOC:mah",
"GOC:rl",
"PMID:12707266"
] | null | [] | [] | [] | [] | [] | [
"GO:0098802"
] | [] | [] | [] | [
"GO:0098802"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0070111 | 70,111 | organellar chromatophore | cellular_component | A bacteroid-containing symbiosome in which the bacterial component is a genetically highly reduced cyanobacterium that is photosynthetically active and incapable of an independent existence outside its host. The chromatophore functions as a photosynthetic organelle, and has been found and characterized in the amoeba Pa... | [
"GOC:expert_mm",
"PMID:18356055"
] | null | [
"Paulinella-type chromatophore"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0043660"
] | [] | [] | [] | [
"GO:0043660"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0070112 | 70,112 | organellar chromatophore membrane | cellular_component | Either of the lipid bilayers that surround an organellar chromatophore. | [
"GOC:mah"
] | null | [
"Paulinella-type chromatophore membrane"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0030659"
] | [
"part_of GO:0070111"
] | [
"part_of"
] | [
"GO:0070111"
] | [
"GO:0030659",
"GO:0070111"
] | [
"GO:0016020",
"part_of GO:0070111"
] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0070113 | 70,113 | organellar chromatophore inner membrane | cellular_component | The inner, i.e. lumen-facing, of the two lipid bilayers surrounding an organellar chromatophore. | [
"GOC:mah"
] | null | [
"Paulinella-type chromatophore inner membrane"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0070112"
] | [] | [] | [] | [
"GO:0070112"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0070114 | 70,114 | organellar chromatophore outer membrane | cellular_component | The outer, i.e. cytoplasm-facing, of the two lipid bilayers surrounding an organellar chromatophore. | [
"GOC:mah"
] | null | [
"Paulinella-type chromatophore outer membrane"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0043661",
"GO:0070112"
] | [] | [] | [] | [
"GO:0043661",
"GO:0070112"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0070115 | 70,115 | organellar chromatophore intermembrane space | cellular_component | The region between the inner and outer lipid bilayers that surround an organellar chromatophore. | [
"GOC:mah"
] | null | [
"Paulinella-type chromatophore intermembrane space"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0110165"
] | [
"part_of GO:0070111"
] | [
"part_of"
] | [
"GO:0070111"
] | [
"GO:0070111",
"GO:0110165"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0070116 | 70,116 | organellar chromatophore thylakoid | cellular_component | A thylakoid located in an organellar chromatophore. | [
"GOC:mah"
] | null | [
"Paulinella-type chromatophore thylakoid"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0009579"
] | [
"part_of GO:0070111"
] | [
"part_of"
] | [
"GO:0070111"
] | [
"GO:0009579",
"GO:0070111"
] | [
"GO:0009579",
"part_of GO:0070111"
] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0070118 | 70,118 | organellar chromatophore thylakoid membrane | cellular_component | The lipid bilayer membrane of any thylakoid within an organellar chromatophore. | [
"GOC:mah"
] | null | [
"Paulinella-type chromatophore thylakoid membrane"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0042651",
"GO:0070112"
] | [
"part_of GO:0070116"
] | [
"part_of"
] | [
"GO:0070116"
] | [
"GO:0042651",
"GO:0070112",
"GO:0070116"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0070119 | 70,119 | ciliary neurotrophic factor binding | molecular_function | Binding to the cytokine ciliary neurotrophic factor. | [
"GOC:BHF",
"GOC:mah"
] | null | [
"CNTF binding"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0019955"
] | [] | [] | [] | [
"GO:0019955"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0070120 | 70,120 | ciliary neurotrophic factor-mediated signaling pathway | biological_process | The series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. | [
"GOC:BHF",
"GOC:mah"
] | null | [
"ciliary neurotrophic factor-mediated signalling pathway",
"CNTF-mediated signaling pathway"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0019221"
] | [] | [] | [] | [
"GO:0019221"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0070121 | 70,121 | Kupffer's vesicle development | biological_process | The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period. | [
"GOC:dgh"
] | null | [
"KV development"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0048856"
] | [] | [] | [] | [
"GO:0048856"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0070123 | 70,123 | transforming growth factor beta receptor activity, type III | molecular_function | Combining with transforming growth factor beta to initiate a change in cell activity; facilitates ligand binding to type I and type II TGF-beta receptors. | [
"GOC:BHF",
"GOC:mah",
"PMID:9759503"
] | null | [
"betaglycan",
"endoglin",
"transforming growth factor beta ligand binding to type III receptor",
"type III TGF-beta receptor activity",
"type III TGFbeta receptor activity",
"type III transforming growth factor beta receptor activity"
] | [
"NARROW",
"NARROW",
"RELATED",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0005024"
] | [] | [] | [] | [
"GO:0005024"
] | [] | [] | [] | [] | [] | [
"skos:broadMatch EC:2.7.11.30",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI"
] | null | null | false | true | 5 |
GO:0070124 | 70,124 | mitochondrial translational initiation | biological_process | The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. | [
"GOC:mah"
] | null | [
"mitochondrial translation initiation"
] | [
"EXACT"
] | [] | [] | [
"Reactome:R-HSA-5368286 \"Mitochondrial translation initiation\""
] | [
"GO:0006413"
] | [
"occurs_in GO:0005739",
"part_of GO:0032543"
] | [
"occurs_in",
"part_of"
] | [
"GO:0005739",
"GO:0032543"
] | [
"GO:0005739",
"GO:0006413",
"GO:0032543"
] | [
"GO:0006413",
"occurs_in GO:0005739"
] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0070125 | 70,125 | mitochondrial translational elongation | biological_process | The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion. | [
"GOC:mah"
] | null | [
"mitochondrial translation elongation"
] | [
"EXACT"
] | [] | [] | [
"Reactome:R-HSA-5389840 \"Mitochondrial translation elongation\""
] | [
"GO:0006414"
] | [
"occurs_in GO:0005739",
"part_of GO:0032543"
] | [
"occurs_in",
"part_of"
] | [
"GO:0005739",
"GO:0032543"
] | [
"GO:0005739",
"GO:0006414",
"GO:0032543"
] | [
"GO:0006414",
"occurs_in GO:0005739"
] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0070126 | 70,126 | mitochondrial translational termination | biological_process | The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa). | [
"GOC:mah",
"http://mitogenome.org/index.php/Genetic_Code_of_mitochondria"
] | null | [
"mitochondrial translation termination"
] | [
"EXACT"
] | [] | [] | [
"Reactome:R-HSA-5419276 \"Mitochondrial translation termination\"",
"Reactome:R-HSA-9937383 \"Mitochondrial ribosome-associated quality control\""
] | [
"GO:0006415"
] | [
"occurs_in GO:0005739",
"part_of GO:0032543"
] | [
"occurs_in",
"part_of"
] | [
"GO:0005739",
"GO:0032543"
] | [
"GO:0005739",
"GO:0006415",
"GO:0032543"
] | [
"GO:0006415",
"occurs_in GO:0005739"
] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0070127 | 70,127 | tRNA aminoacylation for mitochondrial protein translation | biological_process | The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion. | [
"GOC:mah"
] | null | [] | [] | [] | [] | [] | [
"GO:0000959",
"GO:0006418"
] | [
"part_of GO:0032543"
] | [
"part_of"
] | [
"GO:0032543"
] | [
"GO:0000959",
"GO:0006418",
"GO:0032543"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0070129 | 70,129 | regulation of mitochondrial translation | biological_process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. | [
"GOC:mah"
] | null | [
"regulation of mitochondrial protein anabolism",
"regulation of mitochondrial protein biosynthesis",
"regulation of mitochondrial protein formation",
"regulation of mitochondrial protein synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0006417",
"GO:0062125"
] | [
"regulates GO:0032543"
] | [
"regulates"
] | [
"GO:0032543"
] | [
"GO:0006417",
"GO:0032543",
"GO:0062125"
] | [
"GO:0065007",
"regulates GO:0032543"
] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0070130 | 70,130 | negative regulation of mitochondrial translation | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. | [
"GOC:mah"
] | null | [
"negative regulation of mitochondrial protein anabolism",
"negative regulation of mitochondrial protein biosynthesis",
"negative regulation of mitochondrial protein formation",
"negative regulation of mitochondrial protein synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0017148",
"GO:0070129"
] | [
"negatively_regulates GO:0032543"
] | [
"negatively_regulates"
] | [
"GO:0032543"
] | [
"GO:0017148",
"GO:0032543",
"GO:0070129"
] | [
"GO:0065007",
"negatively_regulates GO:0032543"
] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0070131 | 70,131 | positive regulation of mitochondrial translation | biological_process | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. | [
"GOC:mah"
] | null | [
"positive regulation of mitochondrial protein anabolism",
"positive regulation of mitochondrial protein biosynthesis",
"positive regulation of mitochondrial protein formation",
"positive regulation of mitochondrial protein synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0045727",
"GO:0070129"
] | [
"positively_regulates GO:0032543"
] | [
"positively_regulates"
] | [
"GO:0032543"
] | [
"GO:0032543",
"GO:0045727",
"GO:0070129"
] | [
"GO:0065007",
"positively_regulates GO:0032543"
] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0070132 | 70,132 | regulation of mitochondrial translational initiation | biological_process | Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. | [
"GOC:mah"
] | null | [
"regulation of mitochondrial translation initiation"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0006446",
"GO:0070129"
] | [
"regulates GO:0070124"
] | [
"regulates"
] | [
"GO:0070124"
] | [
"GO:0006446",
"GO:0070124",
"GO:0070129"
] | [
"GO:0065007",
"regulates GO:0070124"
] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0070133 | 70,133 | negative regulation of mitochondrial translational initiation | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. | [
"GOC:mah"
] | null | [
"negative regulation of mitochondrial translation initiation"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0045947",
"GO:0070132"
] | [
"negatively_regulates GO:0070124"
] | [
"negatively_regulates"
] | [
"GO:0070124"
] | [
"GO:0045947",
"GO:0070124",
"GO:0070132"
] | [
"GO:0065007",
"negatively_regulates GO:0070124"
] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0070134 | 70,134 | positive regulation of mitochondrial translational initiation | biological_process | Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. | [
"GOC:mah"
] | null | [
"positive regulation of mitochondrial translation initiation"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0045948",
"GO:0070131",
"GO:0070132"
] | [
"positively_regulates GO:0070124"
] | [
"positively_regulates"
] | [
"GO:0070124"
] | [
"GO:0045948",
"GO:0070124",
"GO:0070131",
"GO:0070132"
] | [
"GO:0065007",
"positively_regulates GO:0070124"
] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0070135 | 70,135 | beta-1,2-oligomannoside metabolic process | biological_process | The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan. | [
"GOC:mah",
"PMID:18234669"
] | null | [
"beta-1,2-oligomannoside metabolism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0010412"
] | [] | [] | [] | [
"GO:0010412"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0070136 | 70,136 | beta-1,2-oligomannoside biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan. | [
"GOC:mah",
"PMID:18234669"
] | null | [
"beta-1,2-oligomannoside anabolism",
"beta-1,2-oligomannoside biosynthesis",
"beta-1,2-oligomannoside formation",
"beta-1,2-oligomannoside synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0046354",
"GO:0051278",
"GO:0070135"
] | [] | [] | [] | [
"GO:0046354",
"GO:0051278",
"GO:0070135"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0070137 | 70,137 | ubiquitin-like protein-specific endopeptidase activity | molecular_function | Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO). | [
"GOC:mah"
] | null | [
"small conjugating protein-specific endopeptidase activity"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0004197",
"GO:0019783"
] | [] | [] | [] | [
"GO:0004197",
"GO:0019783"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
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