LiteFold/GO · Datasets at Hugging Face

GO:0097275

97,275

intracellular ammonium homeostasis

biological_process

A homeostatic process involved in the maintenance of a steady state level of ammonium within a cell.

[ "GOC:yaf", "PMID:12695560" ]

null

[ "cellular ammonia homeostasis", "cellular ammonium homeostasis" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0055082", "GO:0097272" ]

[]

[ "GO:0055082", "GO:0097272" ]

[]

pr

2012-03-22T02:54:38Z

false

true

8

GO:0097276

97,276

obsolete cellular creatinine homeostasis

biological_process

OBSOLETE. Any biological process involved in the maintenance of an internal steady state of creatinine at the level of the cell.

[ "GOC:yaf", "PMID:12695560" ]

This term was obsoleted because this process does not exist: creatinine is a waste product, there are no biological processes to maintain its level, although some mutants accumulate excesses.

[]

[ "GO:0003014" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24297\" xsd:anyURI" ]

pr

2012-03-22T02:55:46Z

true

1

GO:0097277

97,277

obsolete cellular urea homeostasis

biological_process

OBSOLETE. Any biological process involved in the maintenance of an internal steady state of urea at the level of the cell.

[ "GOC:yaf", "PMID:12695560" ]

This term was obsoleted because this process does not exist: urea is a waste product, there are no biological processes to maintain its level, although some mutants accumulate excesses.

[]

[ "GO:0003014" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24296\" xsd:anyURI" ]

pr

2012-03-22T02:57:08Z

true

9

GO:0097278

97,278

complement-dependent cytotoxicity

biological_process

Cell killing caused by the membrane attack complex formed following complement activation.

[ "GOC:add", "GOC:rv" ]

null

[]

[ "GO:0001906" ]

[ "has_part GO:0006956" ]

[ "has_part" ]

[ "GO:0006956" ]

[ "GO:0001906", "GO:0006956" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18715\" xsd:anyURI" ]

pr

2012-03-22T05:04:04Z

false

true

8

GO:0097279

97,279

histamine secretion mediated by IgE immunoglobulin

biological_process

Histamine release triggered by the binding of an antigen to an IgE immunoglobulin bound to the cell surface. An example is mast cell histamine degranulation as a result of exposure of mast cell-bound IgE to alder tree pollen.

[ "GOC:add", "GOC:rv" ]

null

[ "histamine secretion mediated by IgE antibody", "Ig-mediated histamine release" ]

[ "EXACT", "BROAD" ]

[]

[ "GO:0097280" ]

[]

[ "GO:0097280" ]

[]

pr

2012-03-22T06:42:13Z

false

true

9

GO:0097280

97,280

histamine secretion mediated by immunoglobulin

biological_process

Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface.

[ "GOC:add", "GOC:rv", "PMID:11490155", "PMID:1719184" ]

null

[]

[ "GO:0002437", "GO:0002441", "GO:0034776" ]

[ "has_part GO:0003823" ]

[ "has_part" ]

[ "GO:0003823" ]

[ "GO:0002437", "GO:0002441", "GO:0003823", "GO:0034776" ]

[]

pr

2012-03-26T01:30:25Z

false

true

6

GO:0097281

97,281

immune complex formation

biological_process

The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of ...

[ "GOC:add", "GOC:rv" ]

null

[ "antibody-mediated agglutination" ]

[ "EXACT" ]

[]

[ "GO:0016064" ]

[ "has_part GO:0003823" ]

[ "has_part" ]

[ "GO:0003823" ]

[ "GO:0003823", "GO:0016064" ]

[]

pr

2012-03-26T01:35:21Z

false

true

1

GO:0097282

97,282

immunoglobulin-mediated neutralization

biological_process

The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin.

[ "GOC:add", "GOC:rv" ]

null

[ "antibody-mediated neutralization" ]

[ "EXACT" ]

[]

[ "GO:0016064" ]

[ "has_part GO:0003823" ]

[ "has_part" ]

[ "GO:0003823" ]

[ "GO:0003823", "GO:0016064" ]

[]

pr

2012-03-26T01:55:24Z

false

true

3

GO:0097283

97,283

keratinocyte apoptotic process

biological_process

Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.

[ "CL:0000312", "GOC:jc", "GOC:mtg_apoptosis", "PMID:10201527" ]

null

[ "keratinocyte apoptosis" ]

[ "NARROW" ]

[]

[ "GO:1904019" ]

[]

[ "GO:1904019" ]

[]

pr

2012-03-29T10:20:51Z

false

true

4

GO:0097284

97,284

hepatocyte apoptotic process

biological_process

Any apoptotic process in a hepatocyte, the main structural component of the liver.

[ "CL:0000182", "GOC:jc", "GOC:mtg_apoptosis", "PMID:15856020" ]

null

[ "hepatocyte apoptosis" ]

[ "NARROW" ]

[]

[ "GO:1904019" ]

[]

[ "GO:1904019" ]

[]

pr

2012-03-29T10:23:21Z

false

true

3

GO:0097285

97,285

obsolete cell-type specific apoptotic process

biological_process

OBSOLETE. Any apoptotic process in a specific cell type.

[ "GOC:mtg_apoptosis" ]

This term was made obsolete because it was an unnecessary grouping term.

[ "cell-type specific apoptosis" ]

[ "NARROW" ]

[]

[ "GO:0006915" ]

[]

pr

2012-03-29T04:00:25Z

true

2

GO:0097287

97,287

7-cyano-7-deazaguanine metabolic process

biological_process

The chemical reactions and pathways involving the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo.

[ "GOC:yaf", "PMID:364423" ]

null

[ "7-cyano-7-deazaguanine metabolism" ]

[ "EXACT" ]

[]

[ "GO:0050898" ]

[]

[ "GO:0050898" ]

[]

pr

2012-04-25T10:50:50Z

false

true

8

GO:0097288

97,288

7-cyano-7-deazaguanine biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo.

[ "GOC:yaf", "PMID:364423" ]

null

[ "7-cyano-7-deazaguanine anabolism", "7-cyano-7-deazaguanine biosynthesis", "7-cyano-7-deazaguanine formation", "7-cyano-7-deazaguanine synthesis" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0080028", "GO:0097287" ]

[]

[ "GO:0080028", "GO:0097287" ]

[]

pr

2012-04-25T10:53:47Z

false

true

4

GO:0097289

97,289

obsolete alpha-ribazole metabolic process

biological_process

OBSOLETE. The chemical reactions and pathways involving alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12).

[ "GOC:yaf" ]

This term was obsoleted because it is an unnecessary grouping class.

[ "alpha-ribazole metabolism" ]

[ "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30524\" xsd:anyURI" ]

pr

2012-04-25T11:49:24Z

true

6

GO:0097290

97,290

obsolete alpha-ribazole biosynthetic process

biological_process

OBSOLETE. The chemical reactions and pathways resulting in the formation of alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12).

[ "GOC:yaf", "MetaCyc:PWY-5508", "MetaCyc:PWY-6269", "UniPathway:UPA00061" ]

This term was obsoleted because it represents a molecular function.

[ "alpha-ribazole anabolism", "alpha-ribazole biosynthesis", "alpha-ribazole formation", "alpha-ribazole synthesis" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0009236", "GO:0043755" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24258\" xsd:anyURI" ]

pr

2012-04-25T11:51:07Z

true

6

GO:0097291

97,291

renal phosphate ion absorption

biological_process

A renal system process in which phosphate ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.

[ "GOC:lb", "PMID:18784102", "PMID:22506049" ]

null

[ "renal phosphate absorption" ]

[ "EXACT" ]

[]

[ "GO:0070293" ]

[]

[ "GO:0070293" ]

[]

pr

2012-04-25T03:34:48Z

false

true

5

GO:0097292

97,292

XMP metabolic process

biological_process

The chemical reactions and pathways involving XMP, xanthosine monophosphate.

[ "GOC:yaf" ]

null

[ "XMP metabolism" ]

[ "EXACT" ]

[]

[ "GO:0009150", "GO:0009167" ]

[]

[ "GO:0009150", "GO:0009167" ]

[]

pr

2012-04-26T09:51:16Z

false

true

7

GO:0097293

97,293

XMP biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate.

[ "GOC:yaf" ]

null

[ "XMP anabolism", "XMP biosynthesis", "XMP formation", "XMP synthesis" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0009152", "GO:0009168", "GO:0097292" ]

[]

[ "GO:0009152", "GO:0009168", "GO:0097292" ]

[]

pr

2012-04-26T09:54:13Z

false

true

4

GO:0097294

97,294

'de novo' XMP biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors.

[ "GOC:yaf", "PMID:27590927" ]

null

[ "'de novo' XMP anabolism", "'de novo' XMP biosynthesis", "'de novo' XMP formation", "'de novo' XMP synthesis" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0097293" ]

[]

[ "GO:0097293" ]

[]

pr

2012-04-26T09:57:49Z

false

true

9

GO:0097295

97,295

morphine biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.

[ "GOC:yaf", "PMID:19567876" ]

null

[ "morphine anabolism", "morphine biosynthesis", "morphine formation", "morphine synthesis" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0033075", "GO:0071272" ]

[]

[ "GO:0033075", "GO:0071272" ]

[]

pr

2012-05-02T09:51:19Z

false

true

6

GO:0097296

97,296

obsolete activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

biological_process

OBSOLETE. Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway.

[ "GOC:mtg_apoptosis" ]

Components of the DISC (death-inducing signaling complex) may be annotated to this term. These include ligand-bound receptors such as FAS/CD95 (though care should be taken because FAS can also act as a non-apoptotic signal transducer), and signaling molecules such as FADD (FAS-associated protein with a death domain), c...

[ "activation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway", "activation of initiator caspase activity" ]

[ "EXACT", "NARROW" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28468\" xsd:anyURI" ]

pr

2012-05-02T03:19:35Z

true

7

GO:0097297

97,297

obsolete activation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

biological_process

OBSOLETE. Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the execution phase of apoptosis.

[ "GOC:mtg_apoptosis" ]

This term was obsoleted because it represents a molecular function.

[ "activation of effector caspase activity" ]

[ "NARROW" ]

[]

[ "GO:0016505" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22455\" xsd:anyURI" ]

pr

2012-05-02T03:23:01Z

true

6

GO:0097298

97,298

regulation of nucleus size

biological_process

Any process that modulates the size of the nucleus.

[ "GOC:al", "GOC:mah", "PMID:19366728" ]

null

[ "regulation of nuclear size", "regulation of nuclear volume" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0032535" ]

[]

[ "GO:0032535" ]

[]

pr

2012-05-03T06:21:43Z

false

true

8

GO:0097299

97,299

obsolete cysteine-type endopeptidase activity involved in plant-type hypersensitive response

molecular_function

OBSOLETE. Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to plant-type hypersensitive response, the rapid, localized death of plant cells in response to in...

[ "GOC:mtg_apoptosis" ]

This term was obsoleted because it represents a GO-CAM model.

[ "metacaspase activity involved in plant-type hypersensitive response" ]

[ "NARROW" ]

[]

pr

2012-05-04T02:09:55Z

true

3

GO:0097300

97,300

programmed necrotic cell death

biological_process

A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.

[ "GOC:mtg_apoptosis", "PMID:21760595" ]

This term may be used when annotating instances of programmed cell death characterized by necrotic morphology where the involvement of RIPK1 and/or RIPK3 is not shown. See PMID:23818611 for some examples.

[ "programmed cell death by necrosis", "regulated necrosis" ]

[ "EXACT", "BROAD" ]

[]

[ "Reactome:R-HSA-5218859 \"Regulated Necrosis\"" ]

[ "GO:0012501" ]

[]

[ "GO:0012501" ]

[]

pr

2012-05-04T03:03:39Z

false

true

2

GO:0097301

97,301

obsolete regulation of potassium ion concentration by positive regulation of transcription from RNA polymerase II promoter

biological_process

OBSOLETE. Any process that regulates the internal concentration of potassium ions at the level of a cell by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.

[ "GOC:dgf", "PMID:20412803" ]

This term was obsoleted because it represents a GO-CAM model.

[ "cellular potassium ion homeostasis by positive regulation of transcription from RNA polymerase II promoter", "potassium ion homeostasis by positive regulation of transcription from RNA polymerase II promoter" ]

[ "EXACT", "BROAD" ]

[]

[ "GO:0045944" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12739\" xsd:anyURI" ]

pr

2012-05-09T09:03:02Z

true

2

GO:0097304

97,304

obsolete lipoprotein biosynthetic process via signal peptide cleavage

biological_process

OBSOLETE. The chemical reactions and pathways by which signal peptide cleavage leads to formation of a water-soluble protein-lipid complex.

[ "GOC:pde", "GOC:yaf", "UniPathway:UPA00665" ]

The reason for obsoletion is that this term represents a molecular function.

[ "lipoprotein biosynthesis (signal peptide cleavage)" ]

[ "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28575\" xsd:anyURI" ]

pr

2012-05-15T01:05:17Z

true

6

GO:0097305

97,305

response to alcohol

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.

[ "GOC:pr", "PMID:24014527" ]

null

[ "process resulting in tolerance to alcohol" ]

[ "NARROW" ]

[ "GO:1990335" ]

[]

[ "GO:1901700" ]

[]

[ "GO:1901700" ]

[]

pr

2012-05-15T03:48:45Z

false

true

7

GO:0097307

97,307

response to farnesol

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.

[ "GOC:pr" ]

null

[]

[ "GO:0033993", "GO:0097305" ]

[]

[ "GO:0033993", "GO:0097305" ]

[]

pr

2012-05-15T03:51:31Z

false

true

2

GO:0097308

97,308

cellular response to farnesol

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.

[ "GOC:di", "PMID:11425711" ]

null

[]

[ "GO:0071396", "GO:0097306", "GO:0097307" ]

[]

[ "GO:0071396", "GO:0097306", "GO:0097307" ]

[]

pr

2012-05-15T03:54:01Z

false

true

3

GO:0097309

97,309

obsolete cap1 mRNA methylation

biological_process

OBSOLETE. Methylation of the ribose of the first nucleotide of a 5'-capped mRNA.

[ "GOC:sp", "PMID:20713356" ]

The reason for obsoletion is that this term represents a molecular function.

[ "cap1 mRNA capping" ]

[ "BROAD" ]

[]

[ "GO:0006370" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26942\" xsd:anyURI" ]

pr

2012-05-23T04:03:13Z

true

1

GO:0097310

97,310

obsolete cap2 mRNA methylation

biological_process

OBSOLETE. Methylation of the ribose of the first and second nucleotides of a 5'-capped mRNA.

[ "GOC:sp", "PMID:20713356" ]

The reason for obsoletion is that this term represents a molecular function.

[ "cap2 mRNA capping" ]

[ "BROAD" ]

[]

[ "GO:0006370" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26942\" xsd:anyURI" ]

pr

2012-05-23T04:05:07Z

true

5

GO:0097311

97,311

bacterial biofilm matrix

cellular_component

A structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.

[ "GOC:imk", "PMID:22571672", "Wikipedia:Biofilm" ]

null

[]

[ "GO:0062039" ]

[]

[ "GO:0062039" ]

[]

pr

2012-05-24T11:20:50Z

false

true

7

GO:0097312

97,312

obsolete bacterial biofilm matrix component

cellular_component

OBSOLETE. Any constituent part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.

[ "GOC:imk", "PMID:22571672", "Wikipedia:Biofilm" ]

Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

[ "biofilm matrix part" ]

[ "EXACT" ]

[]

[ "GO:0097311" ]

[]

pr

2012-05-24T11:22:56Z

true

1

GO:0097313

97,313

bacterial biofilm matrix surface

cellular_component

The external part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.

[ "GOC:imk", "PMID:22571672", "Wikipedia:Biofilm" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0097311" ]

[ "part_of" ]

[ "GO:0097311" ]

[ "GO:0097311", "GO:0110165" ]

[]

pr

2012-05-24T11:25:47Z

false

true

9

GO:0097314

97,314

apoptosome assembly

biological_process

The aggregation, arrangement and bonding together of the apoptosome, a multisubunit protein complex involved in the signaling phase of the apoptotic process.

[ "GOC:mtg_apoptosis" ]

null

[ "apoptosome formation" ]

[ "EXACT" ]

[]

[ "GO:0065003" ]

[ "part_of GO:0097190" ]

[ "part_of" ]

[ "GO:0097190" ]

[ "GO:0065003", "GO:0097190" ]

[]

pr

2012-05-28T03:39:49Z

false

true

6

GO:0097315

97,315

response to N-acetyl-D-glucosamine

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.

[ "GOC:di", "PMID:21700702" ]

null

[]

[ "GO:1901700" ]

[]

[ "GO:1901700" ]

[]

pr

2012-05-30T03:58:54Z

false

true

1

GO:0097316

97,316

cellular response to N-acetyl-D-glucosamine

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.

[ "GOC:di", "PMID:21700702" ]

null

[]

[ "GO:0097315", "GO:1901701" ]

[]

[ "GO:0097315", "GO:1901701" ]

[]

pr

2012-05-30T04:01:02Z

false

true

4

GO:0097317

97,317

invasive growth in response to biotic stimulus

biological_process

The growth of colonies in filamentous chains of cells as a result of a biotic stimulus. An example of this is Candida albicans forming invasive filaments in agar medium in response to a serum stimulus.

[ "GOC:di", "PMID:18679170" ]

null

[]

[ "GO:0036180", "GO:0036267" ]

[]

[ "GO:0036180", "GO:0036267" ]

[]

pr

2012-05-31T10:38:16Z

false

true

8

GO:0097318

97,318

invasive growth in response to abiotic stimulus

biological_process

The growth of colonies in filamentous chains of cells as a result of a abiotic stimulus. An example of this process is found in Candida albicans.

[ "GOC:di", "PMID:18679170" ]

null

[]

[ "GO:0009628", "GO:0036267" ]

[]

[ "GO:0009628", "GO:0036267" ]

[]

pr

2012-05-31T10:39:31Z

false

true

1

GO:0097321

97,321

cell growth mode switching, filamentous to budding

biological_process

The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans.

[ "GOC:di", "PMID:14617167" ]

null

[]

[ "GO:0070784" ]

[]

[ "GO:0070784" ]

[]

pr

2012-06-05T11:28:06Z

false

true

9

GO:0097322

97,322

7SK snRNA binding

molecular_function

Binding to a 7SK small nuclear RNA (7SK snRNA).

[ "GOC:nhn", "PMID:21853533" ]

null

[ "7SK small nuclear RNA binding" ]

[ "EXACT" ]

[]

[ "GO:0017069" ]

[]

[ "GO:0017069" ]

[]

pr

2012-06-05T11:42:23Z

false

true

1

GO:0097323

97,323

B cell adhesion

biological_process

The attachment of a B cell to another cell via adhesion molecules.

[ "GOC:jc" ]

null

[]

[ "GO:0007159" ]

[]

[ "GO:0007159" ]

[]

pr

2012-06-06T01:59:19Z

false

true

3

GO:0097325

97,325

melanocyte proliferation

biological_process

The multiplication or reproduction of melanocytes, resulting in the expansion of a cell population. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.

[ "CL:0000148", "GOC:uh", "PMID:22637532" ]

null

[]

[ "GO:0050673" ]

[]

[ "GO:0050673" ]

[]

pr

2012-06-08T10:10:12Z

false

true

6

GO:0097326

97,326

melanocyte adhesion

biological_process

The attachment of a melanocyte to another cell via adhesion molecules.

[ "CL:0000148", "GOC:uh", "PMID:22637532" ]

null

[]

[ "GO:0090136" ]

[]

[ "GO:0090136" ]

[]

pr

2012-06-08T10:12:03Z

false

true

6

GO:0097327

97,327

response to antineoplastic agent

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms.

[ "GOC:pr" ]

null

[]

[ "GO:0042221" ]

[]

[ "GO:0042221" ]

[]

pr

2012-06-12T10:48:28Z

false

true

1

GO:0097328

97,328

response to carboplatin

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus.

[ "GOC:pr" ]

null

[]

[ "GO:0042221" ]

[]

[ "GO:0042221" ]

[]

pr

2012-06-12T10:50:34Z

false

true

2

GO:0097329

97,329

response to antimetabolite

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces ...

[ "GOC:pr" ]

null

[]

[ "GO:0042221" ]

[]

[ "GO:0042221" ]

[]

pr

2012-06-12T10:52:01Z

false

true

8

GO:0097331

97,331

response to cytarabine

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus.

[ "GOC:pr" ]

null

[]

[ "GO:1901698", "GO:1903416" ]

[]

[ "GO:1901698", "GO:1903416" ]

[]

pr

2012-06-12T10:55:29Z

false

true

5

GO:0097332

97,332

response to antipsychotic drug

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce...

[ "GOC:pr" ]

null

[]

[ "GO:0042221" ]

[]

[ "GO:0042221" ]

[]

pr

2012-06-12T10:58:13Z

false

true

9

GO:0097333

97,333

response to olanzapine

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus.

[ "GOC:pr" ]

null

[]

[ "GO:1901698" ]

[]

[ "GO:1901698" ]

[]

pr

2012-06-12T11:00:04Z

false

true

4

GO:0097334

97,334

response to perphenazine

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piper...

[ "GOC:pr" ]

null

[]

[ "GO:0097305", "GO:1901698" ]

[]

[ "GO:0097305", "GO:1901698" ]

[]

pr

2012-06-12T11:01:14Z

false

true

5

GO:0097335

97,335

response to quetiapine

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quetiapine stimulus.

[ "GOC:pr" ]

null

[]

[ "GO:1901698" ]

[]

[ "GO:1901698" ]

[]

pr

2012-06-12T11:03:22Z

false

true

7

GO:0097336

97,336

response to risperidone

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus.

[ "GOC:pr" ]

null

[]

[ "GO:1901698", "GO:1901700" ]

[]

[ "GO:1901698", "GO:1901700" ]

[]

pr

2012-06-12T11:04:31Z

false

true

8

GO:0097337

97,337

response to ziprasidone

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substi...

[ "GOC:pr" ]

null

[]

[ "GO:1901698" ]

[]

[ "GO:1901698" ]

[]

pr

2012-06-12T11:05:31Z

false

true

3

GO:0097338

97,338

response to clozapine

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus.

[ "GOC:pr" ]

null

[]

[ "GO:1901698" ]

[]

[ "GO:1901698" ]

[]

pr

2012-06-12T11:07:01Z

false

true

7

GO:0097339

97,339

glycolate transmembrane transport

biological_process

The process in which glycolate is transported across a membrane. Glycolate is the anion of hydroxyethanoic acid (glycolic acid).

[ "GOC:am", "PMID:11283302", "PMID:11785976" ]

Note that this term is not intended for use in annotating lateral movement within membranes.

[ "glycolate membrane transport" ]

[ "EXACT" ]

[]

[ "GO:1900866", "GO:1905039" ]

[]

[ "GO:1900866", "GO:1905039" ]

[]

pr

2012-06-12T05:12:35Z

false

true

4

GO:0097340

97,340

obsolete inhibition of cysteine-type endopeptidase activity

biological_process

OBSOLETE. Any process that prevents the activation of an inactive cysteine-type endopeptidase.

[ "GOC:mtg_apoptosis", "PMID:20383739" ]

The reason for obsoletion is that this term represents regulation of a molecular function.

[ "inhibition of caspase activity", "prevention of caspase activity", "prevention of cysteine-type endopeptidase activity" ]

[ "NARROW", "NARROW", "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28468\" xsd:anyURI" ]

pr

2012-06-18T11:23:05Z

true

9

GO:0097341

97,341

zymogen inhibition

biological_process

Any process that prevents the proteolytic processing of an inactive enzyme to an active form.

[ "GOC:mtg_apoptosis", "PMID:20383739" ]

null

[ "prevention of zymogen activation" ]

[ "EXACT" ]

[]

[ "GO:0010955" ]

[]

[ "GO:0010955" ]

[]

pr

2012-06-18T11:25:45Z

false

true

3

GO:0097342

97,342

ripoptosome

cellular_component

A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on se...

[ "GOC:bhm", "GOC:mtg_apoptosis", "PMID:22265414", "PMID:22274400" ]

It has been shown that receptor-mediated necroptotic signaling pathway requires assembly of a ripoptosome protein complex consisting of caspase-8, caspase-10, Fas-associated death domain protein (FADD), casp8 and FADD-like apoptosis regulator (CFLAR) as well as the two receptor-interacting serine/threonine-protein kina...

[ "necrosome", "TNFR1 complex II", "Tnfr1-CII" ]

[ "RELATED", "NARROW", "NARROW" ]

[]

[ "GO:1902494" ]

[ "part_of GO:0005829" ]

[ "part_of" ]

[ "GO:0005829" ]

[ "GO:0005829", "GO:1902494" ]

[]

pr

2012-06-18T12:55:34Z

false

true

9

GO:0097343

97,343

ripoptosome assembly

biological_process

The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, ...

[ "GOC:mtg_apoptosis", "PMID:22274400" ]

null

[]

[ "GO:0065003" ]

[]

[ "GO:0065003" ]

[]

pr

2012-06-18T12:57:20Z

false

true

9

GO:0097344

97,344

obsolete Rix1 complex

cellular_component

OBSOLETE. A protein complex that comprises Rix1p, Ipi1p and Ipi3p, and is required for processing of ITS2 sequences from 35S pre-rRNA. The Rix1 complex has been identified in budding yeast and fission yeast, and members of this complex are conserved in higher eukaryotes.

[ "GOC:vw", "PMID:14759368", "PMID:15260980", "PMID:21385875" ]

redundant, this is the non-catalytic core of Rixosome

[ "IPI complex" ]

[ "EXACT" ]

[]

[ "GO:0120330" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26430\" xsd:anyURI" ]

pr

2012-06-18T01:38:49Z

true

5

GO:0097345

97,345

mitochondrial outer membrane permeabilization

biological_process

The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.

[ "GOC:BHF", "GOC:mtg_apoptosis", "GOC:pg", "PMID:21041309" ]

BAX and BAK are involved in this process, as reviewed in PMID:21760595 (the human proteins have UniProt symbols Q07812 and Q16611 respectively).

[ "mitochondrial outer membrane permeabilization during apoptotic cell death", "mitochondrion outer membrane permeabilization", "MOMP" ]

[ "BROAD", "EXACT", "EXACT" ]

[]

[ "GO:1902110" ]

[ "part_of GO:0097190" ]

[ "part_of" ]

[ "GO:0097190" ]

[ "GO:0097190", "GO:1902110" ]

[]

pr

2012-06-19T04:06:54Z

false

true

3

GO:0097346

97,346

INO80-type complex

cellular_component

A chromatin remodeling protein complex initially purified from S. cerevisiae and containing more than 10 subunits, including the SWR1-related complexes. INO80 (inositol requiring 80)-type complexes have diverse functions, including promoting transcriptional activation and DNA repair.

[ "GOC:rb", "PMID:19355820" ]

null

[]

[ "GO:0070603" ]

[]

[ "GO:0070603" ]

[]

pr

2012-06-20T11:26:55Z

false

true

3

GO:0097347

97,347

TAM protein secretion complex

cellular_component

A heterooligomeric protein complex that spans the bacterial periplasm and enables the secretion of adhesin proteins in Gram-negative bacteria. In Citrobacter rodentium, Salmonella enterica and Escherichia coli, the TAM complex consists of an Omp85-family protein, TamA, in the outer membrane and TamB in the inner membra...

[ "GOC:am", "PMID:22466966" ]

null

[ "translocation and assembly module protein complex" ]

[ "EXACT" ]

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

pr

2012-06-21T10:44:15Z

false

true

7

GO:0097348

97,348

host cell endocytic vesicle membrane

cellular_component

The lipid bilayer surrounding a host cell endocytic vesicle.

[ "GOC:ecd" ]

null

[]

[ "GO:0044162" ]

[]

[ "GO:0044162" ]

[]

pr

2012-06-25T10:31:34Z

false

true

9

GO:0097350

97,350

neutrophil clearance

biological_process

The selective elimination of senescent neutrophils from the body by autoregulatory mechanisms.

[ "GOC:BHF", "PMID:21957127" ]

null

[]

[ "GO:0043277" ]

[ "has_part GO:0006909", "part_of GO:0001780" ]

[ "has_part", "part_of" ]

[ "GO:0006909", "GO:0001780" ]

[ "GO:0001780", "GO:0006909", "GO:0043277" ]

[]

pr

2012-06-27T03:53:38Z

false

true

9

GO:0097351

97,351

toxin sequestering activity

molecular_function

Binding to a toxin to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.

[ "GOC:rs", "PMID:19143615", "PMID:19325885", "PMID:21819231", "PMID:22545240", "PMID:24806488", "Wikipedia:Toxin-antitoxin_system#Type_II" ]

There may be more than one antitoxin to a toxic protein. Instances of this activity are known only in prokaryotes, where the toxic protein may be a ribonuclease, a DNA gyrase, or other.

[ "toxin-antitoxin pair type I binding", "toxin-antitoxin pair type II binding" ]

[ "NARROW", "NARROW" ]

[]

[ "GO:0140313" ]

[]

[ "GO:0140313" ]

[]

pr

2012-06-28T11:41:38Z

false

true

7

GO:0097352

97,352

autophagosome maturation

biological_process

Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling.

[ "GOC:autophagy", "GOC:lf", "PMID:28077293" ]

null

[ "autophagic vacuole fusion", "autophagic vacuole maturation", "autophagosome fusion" ]

[ "EXACT", "EXACT", "RELATED" ]

[ "GO:0000046" ]

[]

[ "GO:0032984" ]

[ "part_of GO:0016236" ]

[ "part_of" ]

[ "GO:0016236" ]

[ "GO:0016236", "GO:0032984" ]

[]

pr

2012-06-28T03:12:18Z

false

true

9

GO:0097354

97,354

prenylation

biological_process

The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added.

[ "GOC:di", "PMID:18029206", "PMID:21351751", "PMID:22123822", "PMID:22642693", "PMID:22660767" ]

null

[]

[ "GO:0008152" ]

[]

[ "GO:0008152" ]

[]

pr

2012-07-03T01:12:19Z

false

true

6

GO:0097355

97,355

protein localization to heterochromatin

biological_process

Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin.

[ "GOC:mah" ]

null

[ "protein localisation to heterochromatin" ]

[ "EXACT" ]

[]

[ "GO:0071168" ]

[]

[ "GO:0071168" ]

[]

pr

2012-07-03T03:19:07Z

false

true

5

GO:0097356

97,356

perinucleolar compartment

cellular_component

The perinucleolar compartment (PNC) is a subnuclear structure associated with, but structurally distinct from, the nucleolus. The PNC contains large amounts of the heterogeneous nuclear ribonucleoprotein complex (hnRNP) called hnRNP 1 (PTB). Many RNA binding proteins as well as RNA polymerase III transcripts are highly...

[ "GOC:vw", "PMID:21385875", "Wikipedia:Perinucleolar_compartment" ]

null

[ "perinucleolar region" ]

[ "EXACT" ]

[]

[ "GO:0110165" ]

[ "part_of GO:0031981" ]

[ "part_of" ]

[ "GO:0031981" ]

[ "GO:0031981", "GO:0110165" ]

[]

pr

2012-07-03T05:11:01Z

false

true

2

GO:0097358

97,358

D-leucyl-tRNA(Leu) deacylase activity

molecular_function

Catalysis of the reaction: D-leucyl-tRNA(Leu) = D-leucine + tRNA(Leu). Removal of a D-leucine from a charged tRNA(Leu).

[ "GOC:se", "PMID:10918062" ]

null

[]

[ "GO:0051499" ]

[]

[ "GO:0051499" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]

pr

2012-07-04T09:18:12Z

false

true

4

GO:0097359

97,359

UDP-glucosylation

biological_process

The covalent attachment of a UDP-glucose residue to a substrate molecule.

[ "GOC:al" ]

null

[]

[ "GO:0006011" ]

[]

[ "GO:0006011" ]

[]

pr

2012-07-06T02:26:35Z

false

true

1

GO:0097360

97,360

chorionic trophoblast cell proliferation

biological_process

The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population.

[ "CL:0011101", "GOC:BHF", "PMID:15150278" ]

null

[]

[ "GO:0008283" ]

[]

[ "GO:0008283" ]

[]

pr

2012-07-19T10:17:37Z

false

true

1

GO:0097361

97,361

cytosolic [4Fe-4S] assembly targeting complex

cellular_component

A protein complex capable of condensing two 2Fe-2S clusters into one 4Fe-4S center in the cytoplasm and nucleus. In humans it consists of MMS19, CIAO1, CIAO2A/CIAO2B, CIAO3. MMS19, CIAO1 and CIAO2A/CIAO2B form a tight 'core' complex, whereas CIAO3 is an 'external' component of this complex.

[ "PMID:23585563", "PMID:23891004", "PMID:34660592" ]

null

[ "CIA complex", "CIA targeting complex", "cytosolic iron-sulfur protein assembly complex" ]

[ "BROAD", "EXACT", "RELATED" ]

[]

[ "GO:0140535", "GO:1990229" ]

[]

[ "GO:0140535", "GO:1990229" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27652\" xsd:anyURI" ]

pr

2012-07-20T02:07:22Z

false

true

2

GO:0097362

97,362

MCM8-MCM9 complex

cellular_component

A hexameric protein complex composed of MCM8 and MCM9 and involved in homologous recombination repair following DNA interstrand cross-links.

[ "GOC:sp", "PMID:22771115", "PMID:22771120" ]

null

[]

[ "GO:0042555" ]

[]

[ "GO:0042555" ]

[]

pr

2012-07-20T02:10:12Z

false

true

7

GO:0097363

97,363

protein O-acetylglucosaminyltransferase activity

molecular_function

Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine, or UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine.

[ "GOC:jsg", "GOC:sart", "PMID:22158438" ]

null

[ "O-GlcNAc transferase", "O-linked N-acetylglucosaminyltransferase", "OGTase", "protein O-GlcNAc transferase activity", "UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "EC:2.4.1.255", "Reactome:R-HSA-8879117 \"POMGNT2 transfers GlcNAc to Man-DAG1\"", "Reactome:R-HSA-9687828 \"O-GlcNAcylation of RIPK3 (TLR4 signaling)\"", "RHEA:48904", "RHEA:48908" ]

[ "GO:0008375", "GO:0140096" ]

[]

[ "GO:0008375", "GO:0140096" ]

[]

[ "skos:exactMatch EC:2.4.1.255", "skos:narrowMatch RHEA:48904", "skos:narrowMatch RHEA:48908", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23320\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

pr

2012-07-24T01:46:51Z

false

true

2

GO:0097364

97,364

obsolete stretch-activated, monoatomic cation-selective, calcium channel activity involved in regulation of action potential

molecular_function

OBSOLETE. Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential.

[ "GOC:BHF", "GOC:mtg_cardiac_conduct_nov11", "PMID:21290758" ]

The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.

[ "stretch-activated, cation-selective, calcium channel activity involved in regulation of action potential" ]

[ "BROAD" ]

[]

[ "GO:0015275" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31205\" xsd:anyURI" ]

pr

2012-07-25T04:08:33Z

true

7

GO:0097365

97,365

obsolete stretch-activated, monoatomic cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential

molecular_function

OBSOLETE. OBSOLETE. Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential in a cardiac muscle cell.

[ "GOC:BHF", "GOC:mtg_cardiac_conduct_nov11", "PMID:21290758" ]

This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.

[ "stretch-activated, cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential" ]

[ "BROAD" ]

[]

[ "GO:0015275" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31205\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]

pr

2012-07-26T02:39:10Z

true

2

GO:0097366

97,366

response to bronchodilator

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes.

[ "GOC:hp" ]

Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.

[ "response to bronchodilator agent", "response to broncholytic agent" ]

[ "EXACT", "RELATED" ]

[]

[ "gocheck_do_not_annotate" ]

[]

[ "GO:0042221" ]

[]

[ "GO:0042221" ]

[]

pr

2012-08-01T16:13:31Z

false

true

1

GO:0097367

97,367

carbohydrate derivative binding

molecular_function

Binding to a carbohydrate derivative.

[ "GOC:pr" ]

null

[]

[ "goslim_agr", "goslim_mouse" ]

[]

[ "GO:0005488" ]

[]

[ "GO:0005488" ]

[]

pr

2012-08-02T13:03:39Z

false

true

1

GO:0097368

97,368

establishment of Sertoli cell barrier

biological_process

Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions.

[ "GOC:sl", "PMID:19509333", "Wikipedia:Blood-testis_barrier" ]

null

[ "establishment of blood-testis barrier", "establishment of BTB", "establishment of SCB" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0060009" ]

[]

[ "GO:0060009" ]

[]

pr

2012-08-02T17:05:55Z

false

true

3

GO:0097370

97,370

obsolete protein O-GlcNAcylation via threonine

biological_process

OBSOLETE. The glycosylation of a protein by addition of N-acetylglucosamine via the O3 atom of peptidyl-threonine, forming O3-N-acetylglucosamine-L-threonine.

[ "GOC:pr", "GOC:sart", "PMID:22158438" ]

The reason for obsoletion is that this term represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29770\" xsd:anyURI" ]

pr

2012-08-06T16:57:37Z

true

5

GO:0097371

97,371

MDM2/MDM4 family protein binding

molecular_function

Binding to a member of the MDM2/MDM4 protein family, comprising negative regulators of p53.

[ "InterPro:IPR016495" ]

null

[]

[ "GO:0005515" ]

[]

[ "GO:0005515" ]

[]

pr

2012-08-08T16:20:59Z

false

true

3

GO:0097372

97,372

histone H3K18 deacetylase activity, NAD-dependent

molecular_function

Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + NAD+ + H2O = histone H3 L-lysine (position 18) + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group attached to a lysine residue in H3K18 to NAD, producing nicotinamide.

[ "GOC:sp", "PMID:22722849", "PMID:28450737" ]

Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...

[ "NAD-dependent histone deacetylase activity (H3-K18 specific)", "NAD-dependent histone H3-K18 deacetylase activity", "NAD-dependent histone H3K18 deacetylase activity" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0017136", "GO:0141050" ]

[]

[ "GO:0017136", "GO:0141050" ]

[]

[ "skos:broadMatch EC:2.3.1.286", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22836\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]

pr

2012-09-05T13:16:39Z

false

true

5

GO:0097373

97,373

MCM core complex

cellular_component

A protein complex that contains Mcm4, Mcm6, and Mcm7 proteins, and possesses DNA helicase activity. In the heterohexameric MCM complex, the Mcm4/6/7 proteins form a stable core, and Mcm2, Mcm3, and Mcm5 are more peripherally associated.

[ "GOC:mah", "PMID:10770926", "PMID:15007098", "PMID:9305914" ]

null

[ "MCM4/6/7 complex" ]

[ "EXACT" ]

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

pr

2012-09-12T10:41:42Z

false

true

2

GO:0097374

97,374

sensory neuron axon guidance

biological_process

The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses.

[ "CL:0000101", "GOC:pr" ]

null

[]

[ "GO:0007411" ]

[]

[ "GO:0007411" ]

[]

pr

2012-10-01T10:16:22Z

false

true

6

GO:0097375

97,375

spinal sensory neuron axon guidance

biological_process

The process in which the migration of an axon growth cone of a spinal sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal sensory neuron is a sensory neuron that project to the spinal cord.

[ "CL:0009000", "GOC:pr", "GOC:yaf" ]

null

[]

[ "GO:0097374" ]

[]

[ "GO:0097374" ]

[]

pr

2012-10-01T10:17:20Z

false

true

6

GO:0097376

97,376

interneuron axon guidance

biological_process

The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain...

[ "CL:0000099", "GOC:pr" ]

null

[]

[ "GO:0007411" ]

[]

[ "GO:0007411" ]

[]

pr

2012-10-01T10:18:35Z

false

true

7

GO:0097377

97,377

spinal cord interneuron axon guidance

biological_process

The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord.

[ "CL:0005000", "GOC:pr" ]

null

[]

[ "GO:0097376" ]

[]

[ "GO:0097376" ]

[]

pr

2012-10-01T10:19:42Z

false

true

7

GO:0097378

97,378

dorsal spinal cord interneuron axon guidance

biological_process

The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A dorsal spinal cord interneuron is an interneuron located in the dorsal part of the spinal cord.

[ "GOC:yaf" ]

null

[ "dorsal interneuron axon guidance" ]

[ "EXACT" ]

[]

[ "GO:0097377" ]

[]

[ "GO:0097377" ]

[]

pr

2012-10-01T10:20:48Z

false

true

4

GO:0097379

97,379

dorsal spinal cord interneuron posterior axon guidance

biological_process

The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs ...

[ "GOC:yaf", "PMID:19545367" ]

null

[ "dorsal interneuron caudal axon projection" ]

[ "RELATED" ]

[]

[ "GO:0033564", "GO:0097378" ]

[]

[ "GO:0033564", "GO:0097378" ]

[]

pr

2012-10-01T10:22:38Z

false

true

9

GO:0097380

97,380

dorsal spinal cord interneuron anterior axon guidance

biological_process

The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs f...

[ "GOC:yaf", "PMID:19545367" ]

null

[ "dorsal interneuron rostral axon projection" ]

[ "RELATED" ]

[]

[ "GO:0033564", "GO:0097378" ]

[]

[ "GO:0033564", "GO:0097378" ]

[]

pr

2012-10-01T10:24:41Z

false

true

5

GO:0097381

97,381

photoreceptor disc membrane

cellular_component

Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ...

[ "GOC:bj", "GOC:krc", "GOC:pde", "PMID:11826267", "PMID:19501669", "PMID:2537204", "PMID:26574505", "PMID:6771304", "PMID:7507907" ]

null

[]

[ "GO:0031090" ]

[ "part_of GO:0001750" ]

[ "part_of" ]

[ "GO:0001750" ]

[ "GO:0001750", "GO:0031090" ]

[]

pr

2012-10-05T11:01:22Z

false

true

6

GO:0097382

97,382

obsolete deoxynucleoside-diphosphatase activity

molecular_function

OBSOLETE. Catalysis of the reaction: a deoxynucleoside diphosphate + H2O = a deoxynucleotide + phosphate.

[ "GOC:pde" ]

This term was obsoleted because it represents an unnecessary grouping class.

[]

[ "GO:0017110" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23401\" xsd:anyURI" ]

pr

2012-10-11T16:03:22Z

true

8

GO:0097383

97,383

dIDP phosphatase activity

molecular_function

Catalysis of the reaction: dIDP + H2O = dIMP + H+ + phosphate.

[ "GOC:pde", "PMID:20385596", "RHEA:35211" ]

null

[ "deoxyinosine-diphosphatase activity" ]

[ "RELATED" ]

[]

[ "Reactome:R-HSA-2509793 \"NUDT16 hydrolyses dIDP to dIMP\"", "RHEA:35211" ]

[ "GO:0017110" ]

[]

[ "GO:0017110" ]

[]

[ "skos:exactMatch RHEA:35211", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

pr

2012-10-11T16:04:40Z

false

true

9

GO:0097384

97,384

obsolete cellular lipid biosynthetic process

biological_process

OBSOLETE. The chemical reactions and pathways resulting in the formation of lipids, as carried out by individual cells.

[ "GOC:pr" ]

The reason for obsoletion is that this term is redundant to GO:008610

[ "cellular lipid anabolism", "cellular lipid biosynthesis", "cellular lipid formation", "cellular lipid synthesis" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0008610" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28975\" xsd:anyURI" ]

pr

2012-10-16T16:47:09Z

true

2

GO:0097385

97,385

programmed necrotic cell death in response to starvation

biological_process

A programmed necrotic cell death occurring as a result of a starvation stimulus (deprivation of nourishment).

[ "GOC:mtg_apoptosis", "GOC:pg", "PMID:13679856" ]

null

[ "necrotic cell death in response to starvation" ]

[ "BROAD" ]

[]

[ "GO:0042594", "GO:0097300" ]

[]

[ "GO:0042594", "GO:0097300" ]

[]

pr

2012-10-22T09:02:18Z

false

true

9

GO:0097386

97,386

glial cell projection

cellular_component

A prolongation or process extending from a glial cell.

[ "GOC:mc" ]

null

[ "glial process", "glial projection" ]

[ "RELATED", "RELATED" ]

[]

[ "GO:0120025" ]

[]

[ "GO:0120025" ]

[]

pr

2012-10-22T13:55:54Z

false

true

4