LiteFold/GO · Datasets at Hugging Face

GO:0097164

97,164

obsolete ammonium ion metabolic process

biological_process

OBSOLETE. The chemical reactions and pathways involving the ammonium ion.

[ "GOC:dhl", "GOC:tb", "PMID:14671018" ]

The reason for obsoletion is that this term was an unnecessary grouping term.

[ "ammonium ion metabolism", "ammonium metabolic process" ]

[ "EXACT", "RELATED" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30537\" xsd:anyURI" ]

pr

2011-09-28T04:21:30Z

true

6

GO:0097165

97,165

nuclear stress granule

cellular_component

A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.

[ "GOC:ans", "PMID:10359787", "PMID:12865437" ]

null

[]

[ "GO:0140168" ]

[]

[ "GO:0140168" ]

[]

pr

2011-09-28T07:49:55Z

false

true

6

GO:0097166

97,166

lens epithelial cell proliferation

biological_process

The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of ...

[ "CL:0002224", "GOC:yaf", "PMID:18423449", "Wikipedia:Lens_%28anatomy%29#Lens_epithelium" ]

null

[]

[ "GO:0050673" ]

[ "part_of GO:0002088" ]

[ "part_of" ]

[ "GO:0002088" ]

[ "GO:0002088", "GO:0050673" ]

[]

pr

2011-09-29T01:27:50Z

false

true

9

GO:0097167

97,167

circadian regulation of translation

biological_process

Any process that modulates the frequency, rate or extent of mRNA translation with a regularity of approximately 24 hours.

[ "GOC:ans", "PMID:17264215" ]

null

[ "regulation of mRNA translation in response to circadian clock" ]

[ "EXACT" ]

[]

[ "GO:0006417", "GO:0007623" ]

[]

[ "GO:0006417", "GO:0007623" ]

[]

pr

2011-09-29T03:13:31Z

false

true

3

GO:0097168

97,168

mesenchymal stem cell proliferation

biological_process

The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.

[ "CL:0000134", "GOC:yaf", "PMID:20626275" ]

null

[ "MSC proliferation" ]

[ "EXACT" ]

[]

[ "GO:0072089" ]

[]

[ "GO:0072089" ]

[]

pr

2011-09-29T04:44:48Z

false

true

4

GO:0097169

97,169

AIM2 inflammasome complex

cellular_component

An inflammasome complex that consists of AIM2, ASC, and caspase-1. AIM2 is a member of the HN-200 protein family that appears to be the sensor of cytosolic double-stranded DNA.

[ "GOC:vp", "PMID:20303873" ]

null

[]

[ "GO:0061702" ]

[]

[ "GO:0061702" ]

[]

pr

2011-10-03T07:36:21Z

false

true

8

GO:0097170

97,170

obsolete ADP-L-glycero-beta-D-manno-heptose metabolic process

biological_process

OBSOLETE. The chemical reactions and pathways involving ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precu...

[ "GOC:yaf" ]

This term was obsoleted because it is an unnecessary grouping class.

[ "ADP-L-glycero-beta-D-manno-heptose metabolism" ]

[ "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30524\" xsd:anyURI" ]

pr

2011-10-03T09:12:58Z

true

5

GO:0097171

97,171

ADP-L-glycero-beta-D-manno-heptose biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-s...

[ "GOC:yaf", "PMID:11751812" ]

null

[ "ADP-L-glycero-beta-D-manno-heptose anabolism", "ADP-L-glycero-beta-D-manno-heptose biosynthesis", "ADP-L-glycero-beta-D-manno-heptose formation", "ADP-L-glycero-beta-D-manno-heptose synthesis" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0009226" ]

[]

[ "GO:0009226" ]

[]

pr

2011-10-03T09:15:03Z

false

true

2

GO:0097172

97,172

N-acetylmuramic acid metabolic process

biological_process

The chemical reactions and pathways involving N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine.

[ "GOC:yaf" ]

null

[ "N-acetylmuramate metabolic process", "N-acetylmuramate metabolism", "N-acetylmuramic acid metabolism" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0019752" ]

[]

[ "GO:0019752" ]

[]

pr

2011-10-07T12:45:24Z

false

true

8

GO:0097173

97,173

N-acetylmuramic acid catabolic process

biological_process

The chemical reactions and pathways resulting in the breakdown of N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine.

[ "GOC:yaf" ]

null

[ "N-acetylmuramate breakdown", "N-acetylmuramate catabolic process", "N-acetylmuramate catabolism", "N-acetylmuramate degradation", "N-acetylmuramic acid breakdown", "N-acetylmuramic acid catabolism", "N-acetylmuramic acid degradation" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0046395", "GO:0097172" ]

[]

[ "GO:0046395", "GO:0097172" ]

[]

pr

2011-10-07T12:48:47Z

false

true

1

GO:0097174

97,174

obsolete 1,6-anhydro-N-acetyl-beta-muramic acid metabolic process

biological_process

OBSOLETE. The chemical reactions and pathways involving 1,6-anhydro-N-acetyl-beta-muramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.

[ "GOC:yaf", "PMID:15901686" ]

This term was obsoleted because it is an unnecessary grouping class.

[ "1,6-anhydro-N-acetyl-beta-muramate metabolic process", "1,6-anhydro-N-acetyl-beta-muramate metabolism", "1,6-anhydro-N-acetyl-beta-muramic acid metabolism", "1,6-anhydro-N-acetylmuramic acid metabolic process", "1,6-anhydro-N-acetylmuramic acid metabolism" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30524\" xsd:anyURI" ]

pr

2011-10-07T12:54:36Z

true

4

GO:0097175

97,175

1,6-anhydro-N-acetyl-beta-muramic acid catabolic process

biological_process

The chemical reactions and pathways resulting in the breakdown of 1,6-anhydro-N-acetylmuramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.

[ "GOC:yaf", "PMID:15901686" ]

null

[ "1,6-anhydro-N-acetyl-beta-muramate breakdown", "1,6-anhydro-N-acetyl-beta-muramate catabolic process", "1,6-anhydro-N-acetyl-beta-muramate catabolism", "1,6-anhydro-N-acetyl-beta-muramate degradation", "1,6-anhydro-N-acetyl-beta-muramic acid breakdown", "1,6-anhydro-N-acetyl-beta-muramic acid catabolism"...

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0072329" ]

[]

[ "GO:0072329" ]

[]

pr

2011-10-07T12:58:32Z

false

true

7

GO:0097176

97,176

epoxide metabolic process

biological_process

The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers.

[ "GOC:rs", "PMID:15822179" ]

null

[ "epoxide metabolism" ]

[ "EXACT" ]

[]

[ "GO:0008152" ]

[]

[ "GO:0008152" ]

[]

pr

2011-10-10T11:29:49Z

false

true

6

GO:0097177

97,177

mitochondrial ribosome binding

molecular_function

Binding to a mitochondrial ribosome.

[ "GOC:ans", "PMID:20739282" ]

null

[]

[ "GO:0043022" ]

[]

[ "GO:0043022" ]

[]

pr

2011-10-11T03:03:03Z

false

true

7

GO:0097178

97,178

ruffle assembly

biological_process

The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as R...

[ "GOC:yaf", "PMID:12556481", "Wikipedia:Membrane_ruffling" ]

null

[ "membrane ruffle formation", "membrane ruffling" ]

[ "EXACT", "EXACT" ]

[]

[ "Wikipedia:Membrane_ruffling" ]

[ "GO:0031529", "GO:0120031" ]

[]

[ "GO:0031529", "GO:0120031" ]

[]

pr

2011-10-16T01:46:09Z

false

true

4

GO:0097179

97,179

protease inhibitor complex

cellular_component

A heterodimeric protein complex that contains a protease inhibitor and a protease; formation of the complex inhibits protease activity.

[ "GOC:ans", "PMID:6323392" ]

null

[ "peptidase inhibitor complex" ]

[ "BROAD" ]

[]

[ "GO:1904090" ]

[]

[ "GO:1904090" ]

[]

pr

2011-10-16T08:53:44Z

false

true

9

GO:0097180

97,180

serine protease inhibitor complex

cellular_component

A heterodimeric protein complex that contains a serine protease inhibitor and a protease; formation of the complex inhibits serine protease activity.

[ "GOC:ans", "PMID:6323392" ]

null

[ "serine-type endopeptidase inhibitor complex", "serpin complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0097179" ]

[]

[ "GO:0097179" ]

[]

pr

2011-10-16T08:55:17Z

false

true

6

GO:0097181

97,181

protein C inhibitor-coagulation factor V complex

cellular_component

A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor V (F5); formation of the complex inhibits the serine protease activity of coagulation factor V.

[ "GOC:ans", "PMID:6323392" ]

null

[ "PCI-coagulation factor V complex", "plasma serine protease inhibitor-coagulation factor V complex", "protein C inhibitor-F5 complex", "serpin A5-coagulation factor V complex", "SERPINA5-coagulation factor V complex" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0097180" ]

[]

[ "GO:0097180" ]

[]

pr

2011-10-16T08:57:03Z

false

true

7

GO:0097182

97,182

protein C inhibitor-coagulation factor Xa complex

cellular_component

A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor Xa (F10); formation of the complex inhibits the serine protease activity of coagulation factor Xa.

[ "GOC:ans", "PMID:6323392" ]

null

[ "PCI-coagulation factor Xa complex", "plasma serine protease inhibitor-coagulation factor Xa complex", "serpin A5-coagulation factor Xa complex", "SERPINA5-coagulation factor Xa complex" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0097180" ]

[]

[ "GO:0097180" ]

[]

pr

2011-10-16T09:01:29Z

false

true

7

GO:0097183

97,183

protein C inhibitor-coagulation factor XI complex

cellular_component

A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor XI (F11); formation of the complex inhibits the serine protease activity of coagulation factor XI.

[ "GOC:ans", "PMID:2844223" ]

null

[ "PCI-coagulation factor XI complex", "plasma serine protease inhibitor-coagulation factor XI complex", "protein C inhibitor-F11 complex", "serpin A5-coagulation factor XI complex", "SERPINA5-coagulation factor XI complex" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0097180" ]

[]

[ "GO:0097180" ]

[]

pr

2011-10-16T09:03:22Z

false

true

9

GO:0097184

97,184

response to azide

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.

[ "GOC:yaf", "PMID:16846222" ]

null

[]

[ "GO:1901698" ]

[]

[ "GO:1901698" ]

[]

pr

2011-11-16T10:00:58Z

false

true

5

GO:0097185

97,185

cellular response to azide

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.

[ "GOC:yaf", "PMID:16846222" ]

null

[]

[ "GO:0097184", "GO:1901699" ]

[]

[ "GO:0097184", "GO:1901699" ]

[]

pr

2011-11-16T10:04:41Z

false

true

9

GO:0097186

97,186

amelogenesis

biological_process

The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage.

[ "GOC:cjm", "GOC:sl", "PMID:10206335", "PMID:21196346" ]

null

[ "enamel development" ]

[ "EXACT" ]

[]

[ "GO:0042475", "GO:0048646" ]

[]

[ "GO:0042475", "GO:0048646" ]

[]

pr

2011-11-21T09:01:24Z

false

true

4

GO:0097187

97,187

dentinogenesis

biological_process

The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin.

[ "GOC:cjm", "GOC:sl", "PMID:10206335", "PMID:21196346" ]

null

[ "dentin development", "dentine development" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0042475", "GO:0048646" ]

[]

[ "GO:0042475", "GO:0048646" ]

[]

pr

2011-11-21T09:04:17Z

false

true

4

GO:0097188

97,188

dentin mineralization

biological_process

The process in which calcium salts are deposited into the calcareous tooth structure known as dentin.

[ "GOC:sl", "PMID:10206335", "PMID:21196346" ]

null

[ "dentine mineralization" ]

[ "EXACT" ]

[]

[ "GO:0034505" ]

[ "part_of GO:0097187" ]

[ "part_of" ]

[ "GO:0097187" ]

[ "GO:0034505", "GO:0097187" ]

[]

pr

2011-11-21T09:05:43Z

false

true

6

GO:0097189

97,189

apoptotic body

cellular_component

A vesicle containing parts of a dying cell. Apoptotic bodies can be formed during the execution phase of the apoptotic process, when the cell's cytoskeleton breaks up and causes the membrane to bulge outward. These bulges may separate from the cell, taking a portion of cytoplasm with them, to become apoptotic bodies. T...

[ "GOC:mtg_apoptosis", "GOC:vesicles", "PMID:15242875", "PMID:24223256", "Wikipedia:Apoptosis", "Wikipedia:Bleb_(cell_biology)" ]

null

[ "apoptotic bleb", "apoptotic vesicle" ]

[ "RELATED", "EXACT" ]

[]

[ "GO:1903561" ]

[]

[ "GO:1903561" ]

[]

pr

2011-11-22T08:05:20Z

false

true

1

GO:0097190

97,190

apoptotic signaling pathway

biological_process

The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.

[ "GOC:mtg_apoptosis" ]

This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to disti...

[ "apoptotic signalling pathway", "induction of apoptosis by extracellular signals" ]

[ "EXACT", "EXACT" ]

[ "GO:0008624" ]

[]

[ "Reactome:R-HSA-111459 \"Activation of caspases through apoptosome-mediated cleavage\"", "Reactome:R-HSA-193681 \"Ceramide signalling\"", "Reactome:R-HSA-204998 \"Cell death signalling via NRAGE, NRIF and NADE\"", "Reactome:R-HSA-75157 \"FasL/ CD95L signaling\"" ]

[ "GO:0007165" ]

[ "part_of GO:0006915" ]

[ "part_of" ]

[ "GO:0006915" ]

[ "GO:0006915", "GO:0007165" ]

[]

pr

2011-11-23T09:30:23Z

false

true

3

GO:0097191

97,191

extrinsic apoptotic signaling pathway

biological_process

The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ...

[ "GOC:mtg_apoptosis", "GOC:yaf", "PMID:17340152" ]

Fas acts as a death receptor with a role in apoptosis, but can also act as a non-apoptotic signal transducer.

[ "death receptor-mediated apoptosis", "extrinsic apoptosis", "extrinsic apoptotic pathway", "extrinsic apoptotic signaling pathway in presence of ligand", "extrinsic apoptotic signalling pathway" ]

[ "NARROW", "NARROW", "EXACT", "NARROW", "EXACT" ]

[]

[ "Reactome:R-HSA-5357769 \"Caspase activation via extrinsic apoptotic signalling pathway\"" ]

[ "GO:0007166", "GO:0097190" ]

[]

[ "GO:0007166", "GO:0097190" ]

[]

pr

2011-11-23T09:34:28Z

false

true

5

GO:0097192

97,192

extrinsic apoptotic signaling pathway in absence of ligand

biological_process

The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.

[ "GOC:mtg_apoptosis", "PMID:15044679", "PMID:20816705" ]

For dependence receptors, absence of a ligand or withdrawal of a ligand from a receptor acts as a signal. An example of 'extrinsic apoptotic signaling pathway in absence of ligand' is withdrawal of a growth factor such as NGF, even if traditionally apoptosis induced via growth factor withdrawal has been classified as a...

[ "dependence receptor signaling pathway", "extrinsic apoptosis in absence of ligand", "extrinsic apoptotic signalling pathway in absence of ligand" ]

[ "RELATED", "NARROW", "EXACT" ]

[]

[ "Reactome:R-HSA-418889 \"Caspase activation via Dependence Receptors in the absence of ligand\"" ]

[ "GO:0038034", "GO:0097191" ]

[]

[ "GO:0038034", "GO:0097191" ]

[]

pr

2011-11-23T09:37:09Z

false

true

9

GO:0097193

97,193

intrinsic apoptotic signaling pathway

biological_process

The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The int...

[ "GOC:mtg_apoptosis", "GOC:yaf", "PMID:11919192", "PMID:17340152", "PMID:18852119" ]

The signals that start intrinsic apoptosis may come from extracellular sources (e.g. oxidative stress, UV exposure), but the reception of the signal and thus the signaling pathway start inside the cell (as a result of DNA damage, redox imbalance, etc.). Examples are ZPR9 (ZNF622) and ASK1 (MAP3K5) (UniProt symbols Q969...

[ "induction of apoptosis by intracellular signals", "intrinsic apoptosis", "intrinsic apoptotic pathway", "intrinsic apoptotic signalling pathway", "mitochondrial-mediated apoptotic pathway" ]

[ "RELATED", "NARROW", "EXACT", "EXACT", "EXACT" ]

[ "GO:0008629" ]

[]

[ "Reactome:R-HSA-109606 \"Intrinsic Pathway for Apoptosis\"" ]

[ "GO:0035556", "GO:0097190" ]

[]

[ "GO:0035556", "GO:0097190" ]

[]

pr

2011-11-23T09:40:50Z

false

true

3

GO:0097195

97,195

pilomotor reflex

biological_process

The reflex process in which the arrectores pilorum (hair follicle) muscles contract and cause the hair to stand erect.

[ "GOC:BHF", "PMID:21335239", "Wikipedia:Pilomotor_reflex" ]

null

[ "goosebump reflex", "horripilation", "piloerection" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0060004" ]

[]

[ "GO:0060004" ]

[]

pr

2011-12-01T05:08:14Z

false

true

8

GO:0097196

97,196

Shu complex

cellular_component

A protein complex involved in error-free DNA post-replication repair (PRR). In Saccharomyces cerevisiae the complex contains Csm2p, Psy3p, Shu1p, and Shu2p.

[ "GOC:jh", "PMID:15654096", "PMID:19496932" ]

null

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

pr

2011-12-01T05:11:08Z

false

true

5

GO:0097198

97,198

obsolete histone H3-K36 trimethylation

biological_process

OBSOLETE. The modification of histone H3 by addition of three methyl groups to lysine at position 36 of the histone.

[ "GOC:se", "PMID:17948059" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]

pr

2011-12-05T01:19:45Z

true

7

GO:0097200

97,200

obsolete cysteine-type endopeptidase activity involved in execution phase of apoptosis

molecular_function

OBSOLETE. Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis.

[ "GOC:mtg_apoptosis", "Wikipedia:Caspase" ]

Examples of gene products that may be annotated to this term include CASP3, CASP6 and CASP7, also called effector (or executioner) caspases.\nThe reason for obsoletion is that this term represents a GO-CAM model.

[ "effector caspase activity", "executioner caspase activity" ]

[ "NARROW", "NARROW" ]

[]

[ "GO:0004197" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28468\" xsd:anyURI" ]

pr

2011-12-12T01:46:06Z

true

2

GO:0097201

97,201

obsolete negative regulation of transcription from RNA polymerase II promoter in response to stress

biological_process

OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

[ "GOC:rn", "PMID:11027285", "PMID:15575969", "PMID:16556235", "PMID:18086556", "PMID:18627600" ]

This term was obsoleted because it represents a GO-CAM model.

[]

[ "GO:0000122", "GO:0033554" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26004\" xsd:anyURI" ]

pr

2011-12-14T09:16:22Z

true

4

GO:0097203

97,203

phagocytic cup lip

cellular_component

The tip or margin of the progressing circular lamella that engulfs a particle during phagocytosis. When the two lips of the cup fuse it is converted into a phagosome.

[ "GOC:pf", "PMID:20200225" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0001891" ]

[ "part_of" ]

[ "GO:0001891" ]

[ "GO:0001891", "GO:0110165" ]

[]

pr

2011-12-21T10:26:41Z

false

true

3

GO:0097204

97,204

phagocytic cup base

cellular_component

The older part of the phagocytic cup where the actin cytoskeleton disassembles, allowing early incoming and outgoing vesicular trafficking.

[ "GOC:pf", "PMID:20200225" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0001891" ]

[ "part_of" ]

[ "GO:0001891" ]

[ "GO:0001891", "GO:0110165" ]

[]

pr

2011-12-21T10:29:07Z

false

true

1

GO:0097205

97,205

renal filtration

biological_process

A renal system process in which fluid circulating through the body is filtered through a barrier system.

[ "GOC:pr", "GOC:sart" ]

null

[]

[ "GO:0003014" ]

[]

[ "GO:0003014" ]

[]

pr

2012-01-03T03:10:17Z

false

true

6

GO:0097206

97,206

nephrocyte filtration

biological_process

The process by which hemolymph is filtered based on size and charge through a nephrocyte filtration barrier formed by the basement membrane and nephrocyte diaphragm.

[ "GOC:sart", "PMID:18971929" ]

null

[]

[ "GO:0097205" ]

[]

[ "GO:0097205" ]

[]

pr

2012-01-03T03:13:31Z

false

true

5

GO:0097207

97,207

bud dormancy process

biological_process

A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a bud. Bud dormancy is a suspension of most physiological activity and growth that can be reactivated. It may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. The e...

[ "GOC:PO_curators", "PO_REF:00009" ]

Bud dormancy may precede dormancy of the whole plant.

[ "bud dormancy" ]

[ "RELATED" ]

[]

[ "GO:0022611", "GO:0032501" ]

[]

[ "GO:0022611", "GO:0032501" ]

[]

pr

2012-01-04T01:18:24Z

false

true

1

GO:0097208

97,208

alveolar lamellar body

cellular_component

A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.

[ "GOC:cjm", "Wikipedia:Lamellar_granule" ]

null

[]

[ "GO:0042599" ]

[]

[ "GO:0042599" ]

[]

pr

2012-01-04T02:33:04Z

false

true

5

GO:0097209

97,209

epidermal lamellar body

cellular_component

A specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function.

[ "GOC:cjm", "Wikipedia:Lamellar_granule" ]

null

[]

[ "GO:0042599" ]

[]

[ "GO:0042599" ]

[]

pr

2012-01-04T02:34:27Z

false

true

1

GO:0097210

97,210

response to gonadotropin-releasing hormone

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stim...

[ "GOC:yaf", "PMID:15976007" ]

null

[ "response to GnRH" ]

[ "EXACT" ]

[]

[ "GO:0043434" ]

[]

[ "GO:0043434" ]

[]

pr

2012-01-09T08:48:56Z

false

true

8

GO:0097211

97,211

cellular response to gonadotropin-releasing hormone

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone...

[ "GOC:yaf", "PMID:15976007" ]

null

[ "cellular response to GnRH", "cellular response to gonadotrophin-releasing hormone" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0071375", "GO:0097210" ]

[]

[ "GO:0071375", "GO:0097210" ]

[]

pr

2012-01-09T08:51:23Z

false

true

6

GO:0097212

97,212

lysosomal membrane organization

biological_process

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.

[ "GOC:yaf", "PMID:20544854" ]

null

[ "lysosomal membrane organisation", "lysosome membrane organization" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0061024" ]

[ "part_of GO:0007040" ]

[ "part_of" ]

[ "GO:0007040" ]

[ "GO:0007040", "GO:0061024" ]

[]

pr

2012-01-12T10:16:15Z

false

true

6

GO:0097213

97,213

regulation of lysosomal membrane permeability

biological_process

Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.

[ "GOC:yaf", "PMID:20544854" ]

null

[ "regulation of lysosome membrane permeability" ]

[ "EXACT" ]

[]

[ "GO:0090559" ]

[]

[ "GO:0090559" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31294\" xsd:anyURI" ]

pr

2012-01-12T10:19:44Z

false

true

8

GO:0097215

97,215

negative regulation of lysosomal membrane permeability

biological_process

Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.

[ "GOC:yaf", "PMID:20544854" ]

null

[ "negative regulation of lysosome membrane permeability" ]

[ "EXACT" ]

[]

[ "GO:0097213", "GO:1905709" ]

[]

[ "GO:0097213", "GO:1905709" ]

[]

pr

2012-01-12T10:23:42Z

false

true

4

GO:0097217

97,217

sieve area

cellular_component

A pit-like area in the cell wall of a sieve element; contains pores lined with callose and occupied by strands of protoplasmic material that interconnect the protoplasts of contiguous sieve elements.

[ "ISBN:0471738433", "POC:curators" ]

Part of a sieve element (PO:0025406).

[]

[ "GO:0110165" ]

[ "part_of GO:0009505" ]

[ "part_of" ]

[ "GO:0009505" ]

[ "GO:0009505", "GO:0110165" ]

[]

pr

2012-01-13T05:39:03Z

false

true

1

GO:0097218

97,218

sieve plate

cellular_component

A part of the cell wall of a sieve tube member that bears one or more highly specialized sieve areas.

[ "ISBN:0471738433", "POC:curators" ]

Typical of angiosperms. Part of sieve tube member (PO:0000289).

[]

[ "GO:0110165" ]

[ "has_part GO:0097217", "part_of GO:0009505" ]

[ "has_part", "part_of" ]

[ "GO:0097217", "GO:0009505" ]

[ "GO:0009505", "GO:0097217", "GO:0110165" ]

[]

pr

2012-01-13T05:42:48Z

false

true

4

GO:0097219

97,219

compound sieve plate

cellular_component

A sieve plate that contains several specialized sieve areas in either a scalariform or reticulate arrangement.

[ "ISBN:0471738433", "POC:curators" ]

Often located on an end wall of a sieve tube member. Unspecialized sieve areas may occur on other parts of the cell.

[]

[ "GO:0097218" ]

[]

[ "GO:0097218" ]

[]

pr

2012-01-13T05:45:23Z

false

true

6

GO:0097220

97,220

simple sieve plate

cellular_component

A sieve plate that contains a single specialized sieve area.

[ "ISBN:0471738433", "POC:curators" ]

Often located on an end wall of a sieve tube member. Unspecialized sieve areas may occur on other parts of the cell.

[]

[ "GO:0097218" ]

[]

[ "GO:0097218" ]

[]

pr

2012-01-13T05:46:46Z

false

true

9

GO:0097221

97,221

M/G1 phase-specific MADS box-forkhead transcription factor complex

cellular_component

A protein complex that contains a MADS-box protein and two forkhead domain proteins, and binds to and regulates transcription from promoters of genes transcribed during the M/G1 transition of the cell cycle. In Schizosaccharomyces pombe, the complex contains the MADS-box protein Mbx1 and two forkhead proteins, Sep1 and...

[ "GOC:mah", "PMID:18057023" ]

null

[ "PBF complex", "PBF transcription complex", "PCB binding factor complex", "pombe cell cycle box binding factor complex" ]

[ "NARROW", "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:0090575" ]

[]

[ "GO:0090575" ]

[]

pr

2012-01-18T08:18:27Z

false

true

3

GO:0097222

97,222

mitochondrial mRNA polyadenylation

biological_process

The enzymatic addition of a sequence of 40-60 adenylyl residues at the 3' end of a eukaryotic mitochondrial mRNA primary transcript. Mitochondria contain both stabilizing and destabilizing poly(A) tails.

[ "GOC:ans", "PMID:18083837" ]

null

[]

[ "GO:0000963" ]

[]

[ "GO:0000963" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28229\" xsd:anyURI" ]

pr

2012-01-24T02:47:19Z

false

true

2

GO:0097223

97,223

obsolete sperm part

cellular_component

OBSOLETE. Any constituent part of a sperm, a mature male germ cell that develops from a spermatid.

[ "GOC:cjm" ]

Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

[]

pr

2012-01-25T01:19:35Z

true

4

GO:0097224

97,224

obsolete sperm connecting piece

cellular_component

OBSOLETE. The segment of the sperm flagellum that attaches to the implantation fossa of the nucleus in the sperm head; from the remnant of the centriole at this point, the axoneme extends throughout the length of the flagellum.

[ "GOC:cjm", "MP:0009830" ]

The reason for obsoletion is that this term is equivalent to GO:0120212 sperm head-tail coupling apparatus.

[]

[ "GO:0120212" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28003\" xsd:anyURI" ]

pr

2012-01-25T01:21:02Z

true

3

GO:0097225

97,225

sperm midpiece

cellular_component

The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates ...

[ "GOC:cjm", "MP:0009831" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0036126" ]

[ "part_of" ]

[ "GO:0036126" ]

[ "GO:0036126", "GO:0110165" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22313\" xsd:anyURI" ]

pr

2012-01-25T01:23:41Z

false

true

6

GO:0097227

97,227

sperm annulus

cellular_component

The ring-like, filamentous structure located at the distal end of the midpiece of the sperm flagellum; the annulus is thought to form a diffusion barrier between the midpiece and the principal piece and serve as a stabilizing structure for tail rigidity.

[ "GOC:cjm", "MP:0009834" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0036126" ]

[ "part_of" ]

[ "GO:0036126" ]

[ "GO:0036126", "GO:0110165" ]

[]

pr

2012-01-25T01:26:17Z

false

true

8

GO:0097228

97,228

sperm principal piece

cellular_component

The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The prin...

[ "GOC:cjm", "MP:0009836" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0036126" ]

[ "part_of" ]

[ "GO:0036126" ]

[ "GO:0036126", "GO:0110165" ]

[]

pr

2012-01-25T01:27:27Z

false

true

1

GO:0097229

97,229

sperm end piece

cellular_component

The short tip of the sperm flagellum, adjacent to the sperm principal piece and furthest from the sperm head, which contains only the axoneme surrounded by the plasma membrane.

[ "GOC:cjm", "GOC:sart", "MP:0009837" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0036126" ]

[ "part_of" ]

[ "GO:0036126" ]

[ "GO:0036126", "GO:0110165" ]

[]

pr

2012-01-25T01:29:04Z

false

true

1

GO:0097230

97,230

cell motility in response to potassium ion

biological_process

Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a potassium ion stimulus.

[ "GOC:pf", "PMID:19363786", "PMID:21239624" ]

null

[ "K+ facilitation of cell motility", "potassium ion facilitation of cell motility" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0048870" ]

[ "part_of GO:0035865" ]

[ "part_of" ]

[ "GO:0035865" ]

[ "GO:0035865", "GO:0048870" ]

[]

pr

2012-01-25T04:39:45Z

false

true

9

GO:0097231

97,231

cell motility in response to calcium ion

biological_process

Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a calcium ion stimulus.

[ "GOC:pf", "PMID:19363786", "PMID:21239624", "PMID:8937985" ]

null

[ "Ca2+ facilitation of cell motility", "calcium ion facilitation of cell motility" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0048870" ]

[ "part_of GO:0071277" ]

[ "part_of" ]

[ "GO:0071277" ]

[ "GO:0048870", "GO:0071277" ]

[]

pr

2012-01-25T04:42:45Z

false

true

1

GO:0097232

97,232

lamellar body membrane

cellular_component

The lipid bilayer surrounding a lamellar body. A lamellar body is a membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has som...

[ "GOC:sl", "PMID:11940594" ]

null

[]

[ "GO:0030667" ]

[ "part_of GO:0042599" ]

[ "part_of" ]

[ "GO:0042599" ]

[ "GO:0030667", "GO:0042599" ]

[]

pr

2012-01-26T10:28:42Z

false

true

5

GO:0097233

97,233

alveolar lamellar body membrane

cellular_component

The lipid bilayer surrounding an alveolar lamellar body, a specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.

[ "GOC:sl", "PMID:11940594" ]

null

[]

[ "GO:0097232" ]

[ "part_of GO:0097208" ]

[ "part_of" ]

[ "GO:0097208" ]

[ "GO:0097208", "GO:0097232" ]

[]

pr

2012-01-26T10:30:24Z

false

true

8

GO:0097234

97,234

epidermal lamellar body membrane

cellular_component

The lipid bilayer surrounding an epidermal lamellar body, a specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function.

[ "GOC:sl", "PMID:11940594" ]

null

[]

[ "GO:0097232" ]

[ "part_of GO:0097209" ]

[ "part_of" ]

[ "GO:0097209" ]

[ "GO:0097209", "GO:0097232" ]

[]

pr

2012-01-26T10:32:13Z

false

true

9

GO:0097235

97,235

obsolete positive regulation of fatty acid beta-oxidation by positive regulation of transcription from RNA polymerase II promoter

biological_process

OBSOLETE. Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.

[ "GOC:dgf", "PMID:1899286" ]

This term was obsoleted because it represents a GO-CAM model.

[]

pr

2012-02-01T05:07:12Z

true

9

GO:0097236

97,236

obsolete positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation

biological_process

OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of zinc ions.

[ "GOC:dgf", "PMID:19702872" ]

This term was obsoleted because it represents a GO-CAM model.

[]

[ "GO:0034224", "GO:0045944" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12739\" xsd:anyURI" ]

pr

2012-02-01T09:33:11Z

true

3

GO:0097237

97,237

cellular response to toxic substance

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.

[ "GOC:pr" ]

null

[]

[ "GO:0009636", "GO:0070887" ]

[]

[ "GO:0009636", "GO:0070887" ]

[]

pr

2012-02-02T12:23:31Z

false

true

3

GO:0097238

97,238

cellular response to methylglyoxal

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.

[ "GOC:pr" ]

null

[]

[ "GO:0051595", "GO:0110096", "GO:1901655" ]

[]

[ "GO:0051595", "GO:0110096", "GO:1901655" ]

[]

pr

2012-02-02T12:26:35Z

false

true

8

GO:0097239

97,239

obsolete positive regulation of transcription from RNA polymerase II promoter in response to methylglyoxal

biological_process

OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a methylglyoxal stimulus.

[ "GOC:dgf", "PMID:15773992" ]

This term was obsoleted because it represents a GO-CAM model.

[]

[ "GO:0045944" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12739\" xsd:anyURI" ]

pr

2012-02-02T12:28:46Z

true

4

GO:0097240

97,240

chromosome attachment to the nuclear envelope

biological_process

The process in which chromatin is anchored to the nuclear envelope.

[ "GOC:vw", "PMID:31635174" ]

null

[ "attachment of chromatin to nuclear envelope" ]

[ "RELATED" ]

[]

[ "GO:0022402", "GO:0050000" ]

[]

[ "GO:0022402", "GO:0050000" ]

[]

pr

2012-02-07T01:11:37Z

false

true

2

GO:0097241

97,241

hematopoietic stem cell migration to bone marrow

biological_process

The orderly movement of a hematopoietic stem cell into the bone marrow, and its subsequent positioning within defined functional compartments in that microenvironment. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune sys...

[ "CL:0000037", "GOC:yaf", "PMID:17368745" ]

null

[ "hematopoietic stem cell homing", "hemopoietic stem cell migration to bone marrow", "progenitor cell homing" ]

[ "BROAD", "EXACT", "BROAD" ]

[]

[ "GO:0035701" ]

[]

[ "GO:0035701" ]

[]

pr

2012-02-09T01:08:32Z

false

true

8

GO:0097242

97,242

amyloid-beta clearance

biological_process

The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors.

[ "GOC:aruk", "GOC:bc", "GOC:BHF", "PMID:18289866", "PMID:19098903", "PMID:26005850" ]

null

[ "beta-amyloid clearance" ]

[ "EXACT" ]

[]

[ "GO:0032501" ]

[]

[ "GO:0032501" ]

[]

pr

2012-02-16T05:32:29Z

false

true

4

GO:0097243

97,243

flavonoid binding

molecular_function

Binding to a flavonoid, a compound containing two or more aromatic rings, each bearing at least one aromatic hydroxyl and connected with a carbon bridge.

[ "GOC:sl", "PMID:20599706" ]

null

[]

[ "GO:0005488" ]

[]

[ "GO:0005488" ]

[]

pr

2012-02-17T03:49:16Z

false

true

3

GO:0097244

97,244

flavonol binding

molecular_function

Binding to a flavonol, a flavonoid that contains a 3-hydroxy-2-phenylchromen-4-one backbone.

[ "GOC:sl" ]

null

[]

[ "GO:0043168", "GO:0097243" ]

[]

[ "GO:0043168", "GO:0097243" ]

[]

pr

2012-02-17T03:50:45Z

false

true

3

GO:0097246

97,246

catechin binding

molecular_function

Binding to a catechin, a polyphenolic antioxidant plant metabolite with a flavonoid or flavan-3-ol structure.

[ "GOC:sl" ]

null

[]

[ "GO:0097245" ]

[]

[ "GO:0097245" ]

[]

pr

2012-02-17T03:53:54Z

false

true

1

GO:0097248

97,248

maintenance of protein location in cell cortex of cell tip

biological_process

A process in which a protein or protein complex is maintained in a specific location in the cell cortex of a cell tip, and is prevented from moving elsewhere. The cell cortex of a cell tip is the region directly beneath the plasma membrane at either end of the longest axis of a cylindrical or elongated cell.

[ "GOC:al", "PMID:19646873" ]

null

[]

[ "GO:0032065" ]

[]

[ "GO:0032065" ]

[]

pr

2012-02-20T04:27:31Z

false

true

9

GO:0097250

97,250

mitochondrial respirasome assembly

biological_process

The aggregation, arrangement and bonding together of respiratory enzyme complexes I, III and IV of the mitochondrial inner membrane to form a large supercomplex.

[ "PMID:30030361", "PMID:32311046" ]

null

[ "mitochondrial respiratory chain supercomplex assembly", "mitochondrial respiratory supercomplex assembly" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0007005", "GO:0033108" ]

[]

[ "GO:0007005", "GO:0033108" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12846\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29227\" xsd:anyURI" ]

pr

2012-02-23T05:18:41Z

false

true

6

GO:0097251

97,251

leukotriene B4 biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.

[ "GOC:yaf" ]

null

[ "leukotriene B4 anabolism", "leukotriene B4 biosynthesis", "leukotriene B4 formation", "leukotriene B4 synthesis", "LTB4 anabolism", "LTB4 biosynthesis", "LTB4 formation", "LTB4 synthesis" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0019370", "GO:0036102", "GO:0042759", "GO:1901570" ]

[]

[ "GO:0019370", "GO:0036102", "GO:0042759", "GO:1901570" ]

[]

pr

2012-02-24T09:34:01Z

false

true

9

GO:0097252

97,252

oligodendrocyte apoptotic process

biological_process

Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons.

[ "CL:0000128", "GOC:mtg_apoptosis", "GOC:yaf", "PMID:16723520" ]

null

[ "oligodendrocyte apoptosis" ]

[ "NARROW" ]

[]

[ "GO:0034349" ]

[]

[ "GO:0034349" ]

[]

pr

2012-03-05T10:51:15Z

false

true

2

GO:0097253

97,253

beta-hydroxybutyrate transmembrane transporter activity

molecular_function

Enables the transfer of beta-hydroxybutyrate from one side of a membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid.

[ "GOC:dsf", "PMID:22302940" ]

null

[ "(R)-3-hydroxybutyrate transmembrane transporter activity", "3-hydroxybutanoic acid transmembrane transporter activity" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0015245", "GO:0015665" ]

[]

[ "GO:0015245", "GO:0015665" ]

[]

pr

2012-03-05T01:22:37Z

false

true

2

GO:0097254

97,254

renal tubular secretion

biological_process

The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs.

[ "GOC:rph", "PMID:25287933", "Wikipedia:Renal_secretion#Secretion" ]

null

[]

[ "GO:0003014", "GO:0007588" ]

[]

[ "GO:0003014", "GO:0007588" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22368\" xsd:anyURI" ]

pr

2012-03-05T02:03:58Z

false

true

5

GO:0097255

97,255

R2TP complex

cellular_component

A highly conserved protein complex comprised of two ATP-dependent DNA helicases (Rvb1p and Rvb2p in yeast, Pontin52 and Reptin52 in humans), Pih1p in yeast or PIH1D1 in humans, and Tah1 in yeast or RPAP3 in humans. The complex associates with Hsp90 and is thought to have a role in assembly of large protein or protein/n...

[ "GOC:mcc", "PMID:15766533", "PMID:21925213" ]

null

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

pr

2012-03-06T11:16:33Z

false

true

2

GO:0097256

97,256

phenyllactate dehydrogenase (NAD+) activity

molecular_function

Catalysis of the reaction: (R)-3-phenyllactate + NAD+ = 3-phenylpyruvate + H+ + NADH.

[ "GOC:pde", "PMID:10849007", "RHEA:38351" ]

This enzymatic activity is usually negligible, but may become prominent when phenylalanine levels are abnormally high as in the human disease phenylketonuria (PKU).

[]

[ "RHEA:38351" ]

[ "GO:0140175" ]

[]

[ "GO:0140175" ]

[]

[ "skos:broadMatch EC:1.1.1.110", "skos:exactMatch RHEA:38351", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21412\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28070\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-onto...

pr

2012-03-07T11:39:39Z

false

true

6

GO:0097257

97,257

leukotriene B4 12-hydroxy dehydrogenase activity

molecular_function

Catalysis of the reaction: leukotriene B4 + NADP+ = 12-oxo-leukotriene B4 + NADPH + H+.

[ "GOC:mw", "KEGG_REACTION:R03864", "PMID:8394361", "PMID:9461497" ]

null

[ "leukotriene B4 12-hydroxydehydrogenase activity" ]

[ "EXACT" ]

[]

[ "Reactome:R-HSA-2161567 \"LTB4 is oxidised to 12-oxoLTB4 by PTGR1\"", "RHEA:50608" ]

[ "GO:0016614" ]

[]

[ "GO:0016614" ]

[]

[ "skos:exactMatch RHEA:50608", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

pr

2012-03-07T02:07:41Z

false

true

9

GO:0097258

97,258

20-hydroxy-leukotriene B4 omega oxidase activity

molecular_function

Catalysis of the reaction: 20-hydroxy-leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-oxo-leukotriene B4 + H+ + 2 H2O + oxidized [NADPH-hemoprotein reductase].

[ "GOC:mw", "PMID:2836406", "PMID:9675028", "RHEA:48668" ]

null

[ "20-hydroxy-leukotriene B4 omega-oxidase activity", "20-hydroxy-leukotriene B4 omega-oxidation" ]

[ "EXACT", "RELATED" ]

[]

[ "Reactome:R-HSA-2161745 \"20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3\"", "RHEA:48668" ]

[ "GO:0004497", "GO:0016614" ]

[]

[ "GO:0004497", "GO:0016614" ]

[]

[ "skos:exactMatch RHEA:48668", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

pr

2012-03-07T03:37:53Z

false

true

1

GO:0097260

97,260

obsolete eoxin A4 synthase activity

molecular_function

OBSOLETE. Catalysis of the reaction: leukotriene A4 = eoxin A4.

[ "GOC:mw", "PMID:18184802", "PMID:18647347" ]

The reason for obsoletion is that this term is equivalent to leukotriene-C4 synthase activity.

[]

[ "GO:0004464" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29695\" xsd:anyURI" ]

pr

2012-03-08T02:57:23Z

true

8

GO:0097261

97,261

eoxin C4 synthase activity

molecular_function

Catalysis of the reaction: eoxin A4 + glutathione = eoxin C4.

[ "GOC:mw", "PMID:18184802", "PMID:18647347" ]

null

[]

[ "Reactome:R-HSA-2161768 \"EXA4 is converted to EXC4 by LTC4S\"" ]

[ "GO:0016846" ]

[]

[ "GO:0016846" ]

[]

pr

2012-03-08T02:59:00Z

false

true

1

GO:0097262

97,262

eoxin D4 synthase activity

molecular_function

Catalysis of the reaction: eoxin C4 = eoxin D4 + 5-L-glutamyl amino acid.

[ "GOC:mw", "PMID:18184802", "PMID:18647347" ]

null

[]

[ "Reactome:R-HSA-2161945 \"EXC4 is converted to EXD4 by GGT\"" ]

[ "GO:0016755" ]

[]

[ "GO:0016755" ]

[]

pr

2012-03-08T03:01:00Z

false

true

8

GO:0097263

97,263

eoxin E4 synthase activity

molecular_function

Catalysis of the reaction: eoxin D4 + H20 = eoxin E4 + glycine.

[ "GOC:mw", "PMID:18184802", "PMID:18647347" ]

null

[]

[ "Reactome:R-HSA-2161868 \"EXD4 is converted to EXE4 by DPEP\"" ]

[ "GO:0008238" ]

[]

[ "GO:0008238" ]

[]

pr

2012-03-08T03:02:48Z

false

true

1

GO:0097264

97,264

self proteolysis

biological_process

The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.

[ "GOC:yaf", "PMID:18676612", "PMID:19144634" ]

null

[ "autolysis", "self-proteolysis" ]

[ "BROAD", "EXACT" ]

[]

[ "GO:0006508" ]

[]

[ "GO:0006508" ]

[]

pr

2012-03-09T12:43:24Z

false

true

1

GO:0097265

97,265

5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity

molecular_function

Catalysis of the reaction: 5-HETE + NADP+ = 5-oxo-ETE + NADPH + H+.

[ "GOC:mw", "PMID:1326548" ]

null

[ "5(S)-HETE dehydrogenase activity", "5-HETE dehydrogenase activity", "5-hydroxy-eicosatetraenoic acid dehydrogenase activity" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "Reactome:R-HSA-2161776 \"5S-HETE is oxidised to 5-oxoETE by 5-HEDH\"" ]

[ "GO:0016616" ]

[]

[ "GO:0016616" ]

[]

pr

2012-03-09T12:46:02Z

false

true

3

GO:0097266

97,266

phenylacetyl-CoA 1,2-epoxidase activity

molecular_function

Catalysis of the reaction: phenylacetyl-CoA + H+ + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+.

[ "EC:1.14.13.149", "GOC:bf", "GOC:gk", "PMID:20660314", "PMID:21247899" ]

null

[ "phenylacetyl-CoA epoxidase activity", "phenylacetyl-CoA monooxygenase activity", "ring 1,2-phenylacetyl-CoA epoxidase activity" ]

[ "EXACT", "RELATED", "RELATED" ]

[]

[ "EC:1.14.13.149", "KEGG_REACTION:R09838", "RHEA:32171" ]

[ "GO:0016709" ]

[]

[ "GO:0016709" ]

[]

[ "skos:exactMatch EC:1.14.13.149", "skos:exactMatch RHEA:32171", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

pr

2012-03-13T09:22:47Z

false

true

3

GO:0097267

97,267

omega-hydroxylase P450 pathway

biological_process

The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation.

[ "GOC:mw", "PMID:10681399" ]

null

[ "P450 omega-hydroxylase pathway" ]

[ "EXACT" ]

[]

[ "Reactome:R-HSA-2142816 \"Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)\"" ]

[ "GO:0019369" ]

[]

[ "GO:0019369" ]

[]

pr

2012-03-15T12:58:15Z

false

true

2

GO:0097268

97,268

cytoophidium

cellular_component

A filamentous, membrane-less subcellular structure composed primarily of polymerized metabolic enzymes, most notably cytidine triphosphate synthase (CTPS). Cytoophidia are evolutionarily conserved structures found across archaea, bacteria, and eukaryotes.

[ "PMID:20513629", "PMID:21930098", "PMID:37248970", "Wikipedia:CTP_synthase#Cytoophidium" ]

null

[]

[ "GO:0099512" ]

[]

[ "GO:0099512" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30793\" xsd:anyURI" ]

pr

2012-03-15T01:00:20Z

false

true

1

GO:0097269

97,269

all-trans-decaprenyl-diphosphate synthase activity

molecular_function

Catalysis of the reaction: 7 isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = all-trans-decaprenyl diphosphate + 7 diphosphate.

[ "PMID:16262699", "RHEA:27802" ]

null

[ "(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity", "2-trans,6-trans-farnesyl diphosphate activity", "decaprenyl pyrophosphate synthetase activity", "decaprenyl-diphosphate synthase activity", "polyprenylpyrophosphate synthetase activity", "terpenoidallyltransferase a...

[ "EXACT", "EXACT", "BROAD", "BROAD", "BROAD", "BROAD", "BROAD", "BROAD" ]

[]

[ "EC:2.5.1.91", "Reactome:R-HSA-2162253 \"PDSS1,2 ligates FPP to IPPP\"", "RHEA:27802" ]

[ "GO:0120531" ]

[]

[ "GO:0120531" ]

[]

[ "skos:exactMatch EC:2.5.1.91", "skos:exactMatch RHEA:27802", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20661\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29264\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontol...

pr

2012-03-20T01:00:23Z

false

true

5

GO:0097270

97,270

dishabituation

biological_process

The temporary recovery of response to a stimulus when a novel stimulus is added.

[ "GOC:kmv", "PMID:11390637", "Wikipedia:Habituation" ]

null

[]

[ "GO:0046958" ]

[]

[ "GO:0046958" ]

[]

pr

2012-03-20T01:39:25Z

false

true

9

GO:0097271

97,271

protein localization to bud neck

biological_process

A process in which a protein is transported to, or maintained at, a location within a cellular bud neck.

[ "GOC:rb", "PMID:22344253" ]

null

[ "protein localisation to bud neck", "protein localization to cellular bud neck" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0008104" ]

[]

[ "GO:0008104" ]

[]

pr

2012-03-20T03:39:20Z

false

true

5

GO:0097272

97,272

ammonium homeostasis

biological_process

Any biological process involved in the maintenance of an internal steady state of ammonium.

[ "GOC:yaf", "PMID:12695560" ]

null

[ "ammonia homeostasis" ]

[ "EXACT" ]

[]

[ "GO:0098771" ]

[]

[ "GO:0098771" ]

[]

pr

2012-03-22T02:51:22Z

false

true

3

GO:0097273

97,273

obsolete creatinine homeostasis

biological_process

OBSOLETE. Any biological process involved in the maintenance of an internal steady state of creatinine.

[ "GOC:yaf", "PMID:12695560" ]

This term was obsoleted because this process does not exist: creatinine is a waste product, there are no biological processes to maintain its level, although some mutants accumulate excesses.

[]

[ "GO:0003014" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24297\" xsd:anyURI" ]

pr

2012-03-22T02:52:50Z

true

6

GO:0097274

97,274

obsolete urea homeostasis

biological_process

OBSOLETE. Any biological process involved in the maintenance of an internal steady state of urea.

[ "GOC:yaf", "PMID:12695560" ]

This term was obsoleted because this process does not exist: urea is a waste product, there are no biological processes to maintain its level, although some mutants accumulate excesses.

[]

[ "GO:0003014" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24296\" xsd:anyURI" ]

pr

2012-03-22T02:53:39Z

true

8