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go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0098913
98,913
membrane depolarization during ventricular cardiac muscle cell action potential
biological_process
The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
[ "GOC:dph", "GOC:mtg_cardiac_conduct_nov11", "GOC:tb" ]
null
[ "electrocardiogram QRS complex", "ventricular depolarization" ]
[ "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0086012" ]
[ "part_of GO:0086005" ]
[ "part_of" ]
[ "GO:0086005" ]
[ "GO:0086005", "GO:0086012" ]
[ "GO:0051899", "part_of GO:0086005" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0098915
98,915
membrane repolarization during ventricular cardiac muscle cell action potential
biological_process
The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
[ "GOC:BHF", "GOC:dph", "GOC:mtg_cardiac_conduct_nov11", "GOC:tb" ]
null
[ "electrocardiogram T wave", "regulation of ventricular cardiac muscle repolarization", "ventricular repolarization" ]
[ "RELATED", "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0086013", "GO:0099625" ]
[ "part_of GO:0086005" ]
[ "part_of" ]
[ "GO:0086005" ]
[ "GO:0086005", "GO:0086013", "GO:0099625" ]
[ "GO:0086009", "part_of GO:0086005" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0098916
98,916
anterograde trans-synaptic signaling
biological_process
Cell-cell signaling from pre to post-synapse, across the synaptic cleft.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0099537" ]
[]
[]
[]
[ "GO:0099537" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0098917
98,917
retrograde trans-synaptic signaling
biological_process
Cell-cell signaling from post to pre-synapse, across the synaptic cleft.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0099537" ]
[]
[]
[]
[ "GO:0099537" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0098918
98,918
structural constituent of synapse
molecular_function
The action of a molecule that contributes to the structural integrity of a synapse.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0005198" ]
[ "occurs_in GO:0045202", "part_of GO:0050808" ]
[ "occurs_in", "part_of" ]
[ "GO:0045202", "GO:0050808" ]
[ "GO:0005198", "GO:0045202", "GO:0050808" ]
[ "GO:0005198", "occurs_in GO:0045202", "part_of GO:0050808" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0098919
98,919
structural constituent of postsynaptic density
molecular_function
The action of a molecule that contributes to the structural integrity of a postsynaptic density.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098879" ]
[ "occurs_in GO:0014069", "part_of GO:0099562" ]
[ "occurs_in", "part_of" ]
[ "GO:0014069", "GO:0099562" ]
[ "GO:0014069", "GO:0098879", "GO:0099562" ]
[ "GO:0005198", "occurs_in GO:0014069", "part_of GO:0099562" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0098920
98,920
retrograde trans-synaptic signaling by lipid
biological_process
Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098917", "GO:0099541" ]
[]
[]
[]
[ "GO:0098917", "GO:0099541" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0098921
98,921
retrograde trans-synaptic signaling by endocannabinoid
biological_process
Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an endocannabinoid ligand.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098920", "GO:0099542" ]
[]
[]
[]
[ "GO:0098920", "GO:0099542" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0098922
98,922
extrinsic component of dense core granule membrane
cellular_component
The component of the dense core granule membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0031312" ]
[ "part_of GO:0032127" ]
[ "part_of" ]
[ "GO:0032127" ]
[ "GO:0031312", "GO:0032127" ]
[ "GO:0019898", "part_of GO:0032127" ]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0098923
98,923
retrograde trans-synaptic signaling by soluble gas
biological_process
Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098917", "GO:0099543" ]
[]
[]
[]
[ "GO:0098917", "GO:0099543" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0098924
98,924
retrograde trans-synaptic signaling by nitric oxide
biological_process
Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098923", "GO:0099548" ]
[]
[]
[]
[ "GO:0098923", "GO:0099548" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0098925
98,925
retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission
biological_process
Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.
[ "GOC:dos" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098924", "GO:0099555" ]
[]
[]
[]
[ "GO:0098924", "GO:0099555" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0098926
98,926
postsynaptic signal transduction
biological_process
Signal transduction in which the initial step occurs in a postsynapse.
[ "GOC:dos" ]
null
[ "postsynaptic signaling pathway" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0007165" ]
[ "part_of GO:0099536" ]
[ "part_of" ]
[ "GO:0099536" ]
[ "GO:0007165", "GO:0099536" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0098927
98,927
vesicle-mediated transport between endosomal compartments
biological_process
A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome.
[ "GOC:dos", "PMID:10930469" ]
null
[]
[]
[]
[]
[]
[ "GO:0010496", "GO:0016197" ]
[]
[]
[]
[ "GO:0010496", "GO:0016197" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26386\" xsd:anyURI" ]
null
null
false
true
4
GO:0098928
98,928
presynaptic signal transduction
biological_process
Signal transduction in which the initial step occurs in a presynapse.
[ "GOC:dos" ]
null
[ "presynaptic signaling pathway" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0007165" ]
[]
[]
[]
[ "GO:0007165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0098929
98,929
obsolete extrinsic component of spine apparatus membrane
cellular_component
OBSOLETE. The component of the spine apparatus membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
[ "GOC:dos" ]
This term was obsoleted because it represents protein topology, not a cellular component.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0098897" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]
null
null
true
true
8
GO:0098930
98,930
axonal transport
biological_process
The directed movement of organelles or molecules along microtubules in axons.
[ "ISBN:0815316194" ]
null
[ "axon cargo transport", "axoplasmic transport" ]
[ "EXACT", "EXACT" ]
[]
[ "goslim_synapse" ]
[ "Wikipedia:Axoplasmic_transport" ]
[ "GO:0008088" ]
[ "occurs_in GO:0030424" ]
[ "occurs_in" ]
[ "GO:0030424" ]
[ "GO:0008088", "GO:0030424" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0098931
98,931
virion attachment to host cell flagellum
biological_process
The process by which a virion attaches to a the host cell flagellum. Some DNA bacterial viruses use flagella to attach to the host cell. This contact with the flagellum facilitates concentration of phage particles around the entry receptor on the bacterial cell surface.
[ "GOC:dos", "VZ:3949" ]
null
[]
[]
[]
[]
[ "VZ:3949" ]
[ "GO:0019062" ]
[]
[]
[]
[ "GO:0019062" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0098932
98,932
symbiont entry into host cell via disruption of host cell wall peptidoglycan
biological_process
The disruption by a symbiont of host cell wall peptidoglycans to allow entry into the host cell.
[ "GOC:dos", "VZ:3940" ]
null
[ "catabolism of host cell wall peptidoglycan by virus", "degradation of host cell wall peptidoglycan by virus", "degradation of host peptidoglycans during virus entry", "disassembly by virus of host cell wall peptidoglycan", "disruption by virus of host cell wall peptidoglycan during virus entry" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "VZ:3940" ]
[ "GO:0052009" ]
[ "part_of GO:0046718" ]
[ "part_of" ]
[ "GO:0046718" ]
[ "GO:0046718", "GO:0052009" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26670\" xsd:anyURI" ]
null
null
false
true
5
GO:0098933
98,933
symbiont-mediated disruption of host cell envelope
biological_process
The process in which a symbiont effects a change that impairs the structure or function of the host cell envelope. The host is defined as the larger of the organisms involved in a symbiotic interaction.
[ "ISBN:0198547684" ]
null
[ "disruption by symbiont of host cell envelope" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0052008" ]
[]
[]
[]
[ "GO:0052008" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0098934
98,934
retrograde dendritic transport
biological_process
The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098935" ]
[ "occurs_in GO:0032839" ]
[ "occurs_in" ]
[ "GO:0032839" ]
[ "GO:0032839", "GO:0098935" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0098935
98,935
dendritic transport
biological_process
The directed movement of organelles or molecules along microtubules in dendrites.
[ "ISBN:0815316194" ]
null
[ "dendrite cargo transport" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0008088" ]
[ "occurs_in GO:0030425" ]
[ "occurs_in" ]
[ "GO:0030425" ]
[ "GO:0008088", "GO:0030425" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0098936
98,936
obsolete intrinsic component of postsynaptic membrane
cellular_component
OBSOLETE. The component of the postsynaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
[ "GOC:dos", "GOC:mah" ]
This term was obsoleted because it represents protein topology, not a cellular component.
[ "intrinsic to postsynaptic membrane" ]
[ "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0045211" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]
null
null
true
true
3
GO:0098937
98,937
anterograde dendritic transport
biological_process
The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites.
[ "ISBN:0815316194" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098935" ]
[ "occurs_in GO:0032839" ]
[ "occurs_in" ]
[ "GO:0032839" ]
[ "GO:0032839", "GO:0098935" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0098938
98,938
actin cytoskeleton of dendritic spine
cellular_component
The actin cytoskeleton that is part of a dendritic spine.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098836", "GO:0098871" ]
[]
[]
[]
[ "GO:0098836", "GO:0098871" ]
[ "GO:0015629", "part_of GO:0043197" ]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0098939
98,939
dendritic transport of mitochondrion
biological_process
The directed movement of mitochondria along microtubules in nerve cell dendrites.
[ "GOC:ai" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0047497", "GO:0098935" ]
[ "occurs_in GO:0032839" ]
[ "occurs_in" ]
[ "GO:0032839" ]
[ "GO:0032839", "GO:0047497", "GO:0098935" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0098940
98,940
anterograde trans-synaptic signaling by nitric oxide
biological_process
Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098916", "GO:0099548" ]
[]
[]
[]
[ "GO:0098916", "GO:0099548" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0098941
98,941
anterograde trans-synaptic signaling by trans-synaptic protein complex
biological_process
Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098916", "GO:0099545" ]
[]
[]
[]
[ "GO:0098916", "GO:0099545" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0098942
98,942
retrograde trans-synaptic signaling by trans-synaptic protein complex
biological_process
Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098917", "GO:0099545" ]
[]
[]
[]
[ "GO:0098917", "GO:0099545" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0098943
98,943
neurotransmitter receptor transport, postsynaptic endosome to lysosome
biological_process
The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation.
[ "GOC:dos" ]
null
[ "postsynaptic neurotransmitter receptor endosomal trafficking" ]
[ "BROAD" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0006886", "GO:0008333", "GO:0061462", "GO:0072666", "GO:0099637" ]
[]
[]
[]
[ "GO:0006886", "GO:0008333", "GO:0061462", "GO:0072666", "GO:0099637" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0098944
98,944
postsynaptic recycling endosome membrane
cellular_component
The lipid bilayer surrounding a postsynaptic recycling endosome.
[ "GOC:pz" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098895" ]
[ "part_of GO:0098837" ]
[ "part_of" ]
[ "GO:0098837" ]
[ "GO:0098837", "GO:0098895" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0098945
98,945
obsolete intrinsic component of presynaptic active zone membrane
cellular_component
OBSOLETE. The component of the presynaptic active zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
[ "GOC:dos", "GOC:mah" ]
This term was obsoleted because it represents protein topology, not a cellular component.
[ "intrinsic to presynaptic active zone membrane" ]
[ "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0048787" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]
null
null
true
true
1
GO:0098946
98,946
obsolete intrinsic component of presynaptic endocytic zone membrane
cellular_component
OBSOLETE. The component of the presynaptic endocytic zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane...
[ "GOC:dos", "GOC:mah" ]
This term was obsoleted because it represents protein topology, not a cellular component.
[ "intrinsic to presynaptic active zone membrane" ]
[ "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0098835" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]
null
null
true
true
1
GO:0098947
98,947
obsolete intrinsic component of postsynaptic endocytic zone membrane
cellular_component
OBSOLETE. The component of the postsynaptic endocytic zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membran...
[ "GOC:dos", "GOC:mah" ]
This term was obsoleted because it represents protein topology, not a cellular component.
[ "intrinsic to postsynaptic active zone membrane" ]
[ "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0098844" ]
[]
[]
null
null
true
true
2
GO:0098949
98,949
obsolete intrinsic component of postsynaptic endosome membrane
cellular_component
OBSOLETE. The component of the postsynaptic endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
[ "GOC:dos", "GOC:mah" ]
This term was obsoleted because it represents protein topology, not a cellular component.
[ "intrinsic to postsynaptic endosome membrane" ]
[ "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0098895" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]
null
null
true
true
3
GO:0098950
98,950
obsolete intrinsic component of postsynaptic early endosome membrane
cellular_component
OBSOLETE. The component of the postsynaptic early endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membran...
[ "GOC:dos", "GOC:mah" ]
This term was obsoleted because it represents protein topology, not a cellular component.
[ "intrinsic to postsynaptic early endosome membrane" ]
[ "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0098896" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]
null
null
true
true
7
GO:0098951
98,951
obsolete intrinsic component of postsynaptic recycling endosome membrane
cellular_component
OBSOLETE. The component of the postsynaptic recycling endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the mem...
[ "GOC:dos", "GOC:mah" ]
This term was obsoleted because it represents protein topology, not a cellular component.
[ "intrinsic to postsynaptic recycling endosome membrane" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0098944" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]
null
null
true
true
9
GO:0098952
98,952
obsolete intrinsic component of spine apparatus membrane
cellular_component
OBSOLETE. The component of the spine apparatus membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
[ "GOC:dos", "GOC:mah" ]
This term was obsoleted because it represents protein topology, not a cellular component.
[ "intrinsic to spine apparatus membrane" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0098897" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]
null
null
true
true
2
GO:0098953
98,953
receptor diffusion trapping
biological_process
The process by which a membrane receptor, diffusing freely within the plasma membeane, becomes trapped in some plasma membrane region. This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix.
[ "PMID:18832033" ]
null
[]
[]
[]
[]
[]
[ "GO:0051668" ]
[ "occurs_in GO:0005886" ]
[ "occurs_in" ]
[ "GO:0005886" ]
[ "GO:0005886", "GO:0051668" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0098954
98,954
presynaptic endosome membrane
cellular_component
The lipid bilayer surrounding a presynaptic endosome.
[ "GOC:pz" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0010008" ]
[ "part_of GO:0098830" ]
[ "part_of" ]
[ "GO:0098830" ]
[ "GO:0010008", "GO:0098830" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0098955
98,955
obsolete intrinsic component of presynaptic endosome membrane
cellular_component
OBSOLETE. The component of the presynaptic endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
[ "GOC:dos", "GOC:mah" ]
This term was obsoleted because it represents protein topology, not a cellular component.
[ "intrinsic to presynaptic endosome membrane" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0098954" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]
null
null
true
true
9
GO:0098957
98,957
anterograde axonal transport of mitochondrion
biological_process
The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.
[ "GOC:dos" ]
null
[ "anterograde axon transport of mitochondria" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0008089", "GO:0019896" ]
[]
[]
[]
[ "GO:0008089", "GO:0019896" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0098958
98,958
retrograde axonal transport of mitochondrion
biological_process
The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse.
[ "GOC:dos" ]
null
[ "retrograde axon transport of mitochondria" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0008090", "GO:0019896" ]
[]
[]
[]
[ "GO:0008090", "GO:0019896" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0098959
98,959
retrograde dendritic transport of mitochondrion
biological_process
The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse.
[ "GOC:dos" ]
null
[ "retrograde dendrite transport of mitochondria" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098939" ]
[]
[]
[]
[ "GO:0098939" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0098960
98,960
postsynaptic neurotransmitter receptor activity
molecular_function
Neurotransmitter receptor activity occurring in the postsynaptic membrane during synaptic transmission.
[ "GOC:dos", "GOC:signaling" ]
null
[ "neurotransmitter receptor activity involved in chemical synaptic transmission" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0030594" ]
[ "occurs_in GO:0045211", "part_of GO:0099565" ]
[ "occurs_in", "part_of" ]
[ "GO:0045211", "GO:0099565" ]
[ "GO:0030594", "GO:0045211", "GO:0099565" ]
[ "GO:0030594", "part_of GO:0007268" ]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0098961
98,961
dendritic transport of ribonucleoprotein complex
biological_process
The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites.
[ "GOC:dos" ]
null
[ "dendritic transport of RNP complex" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098935" ]
[ "occurs_in GO:0032839" ]
[ "occurs_in" ]
[ "GO:0032839" ]
[ "GO:0032839", "GO:0098935" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0098962
98,962
obsolete regulation of postsynaptic neurotransmitter receptor activity
biological_process
OBSOLETE. Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector function such as ion selectivity or pore opening/closing in ionotropic receptors.
[ "GOC:dos" ]
This term was obsoleted because it represents a molecular function. Consider molecular function regulator activity ; GO:0098772 or a child.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22455\" xsd:anyURI" ]
null
null
true
true
3
GO:0098963
98,963
dendritic transport of messenger ribonucleoprotein complex
biological_process
The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites.
[ "GOC:dos" ]
null
[ "dendritic transport of mRNA RNP complex" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098935" ]
[]
[]
[]
[ "GO:0098935" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0098964
98,964
anterograde dendritic transport of messenger ribonucleoprotein complex
biological_process
The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites towards the postsynapse.
[ "GOC:dos" ]
null
[ "anterograde dendritic transport of mRNA RNP complex" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098937" ]
[]
[]
[]
[ "GO:0098937" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0098965
98,965
extracellular matrix of synaptic cleft
cellular_component
The portion of the extracellular matrix that lies within the synaptic cleft.
[ "GOC:dos" ]
null
[ "ECM of synaptic cleft", "synaptic cleft ECM" ]
[ "EXACT", "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0140047" ]
[ "part_of GO:0099535" ]
[ "part_of" ]
[ "GO:0099535" ]
[ "GO:0099535", "GO:0140047" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0098966
98,966
perisynaptic extracellular matrix
cellular_component
The portion of the extracellular matrix that lies within the perisynaptic space.
[ "GOC:dos" ]
null
[ "extrasynaptic extracellular matrix", "perisynaptic ECM" ]
[ "EXACT", "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099535" ]
[]
[]
[]
[ "GO:0099535" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0098967
98,967
exocytic insertion of neurotransmitter receptor to postsynaptic membrane
biological_process
The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion.
[ "PMID:19503082" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0006887", "GO:0099072" ]
[ "part_of GO:0098969" ]
[ "part_of" ]
[ "GO:0098969" ]
[ "GO:0006887", "GO:0098969", "GO:0099072" ]
[ "GO:0006887", "part_of GO:0098969" ]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0098968
98,968
neurotransmitter receptor transport postsynaptic membrane to endosome
biological_process
Vesicle-mediated transport of a neurotransmitter receptor complex from the postsynaptic membrane to the postsynaptic early endosome.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0016192", "GO:0097120" ]
[]
[]
[]
[ "GO:0016192", "GO:0097120" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0098969
98,969
neurotransmitter receptor transport to postsynaptic membrane
biological_process
The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0097120", "GO:0098877", "GO:0099072", "GO:1903539", "GO:1903540" ]
[]
[]
[]
[ "GO:0097120", "GO:0098877", "GO:0099072", "GO:1903539", "GO:1903540" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0098970
98,970
postsynaptic neurotransmitter receptor diffusion trapping
biological_process
The process by which diffusing neurotransmitter receptor becomes trapped at the postsynaptic specialization membrane. This is typically due to interaction with components of the post-synaptic specialization.
[ "PMID:18832033" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0097120", "GO:0099072", "GO:0099628" ]
[ "occurs_in GO:0045211", "occurs_in GO:0099634" ]
[ "occurs_in", "occurs_in" ]
[ "GO:0045211", "GO:0099634" ]
[ "GO:0045211", "GO:0097120", "GO:0099072", "GO:0099628", "GO:0099634" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0098971
98,971
anterograde dendritic transport of neurotransmitter receptor complex
biological_process
The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0097120", "GO:0098937" ]
[]
[]
[]
[ "GO:0097120", "GO:0098937" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0098972
98,972
anterograde dendritic transport of mitochondrion
biological_process
The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098937", "GO:0098939" ]
[]
[]
[]
[ "GO:0098937", "GO:0098939" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0098973
98,973
structural constituent of postsynaptic actin cytoskeleton
molecular_function
The action of a molecule that contributes to the structural integrity of a postsynaptic actin cytoskeleton.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0005200", "GO:0099186" ]
[ "occurs_in GO:0098871", "part_of GO:0098974" ]
[ "occurs_in", "part_of" ]
[ "GO:0098871", "GO:0098974" ]
[ "GO:0005200", "GO:0098871", "GO:0098974", "GO:0099186" ]
[ "GO:0005198", "occurs_in GO:0098871", "part_of GO:0098974" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0098974
98,974
postsynaptic actin cytoskeleton organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0030036", "GO:0099188" ]
[]
[]
[]
[ "GO:0030036", "GO:0099188" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0098975
98,975
postsynapse of neuromuscular junction
cellular_component
The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma.
[ "GOC:dos", "Wikipedia:Neuromuscular_junction&oldid=723623502" ]
null
[]
[]
[]
[]
[]
[ "GO:0098794" ]
[ "part_of GO:0031594" ]
[ "part_of" ]
[ "GO:0031594" ]
[ "GO:0031594", "GO:0098794" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0098976
98,976
excitatory chemical synaptic transmission
biological_process
Synaptic transmission that results in an excitatory postsynaptic potential.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0007268" ]
[ "has_part GO:0060079" ]
[ "has_part" ]
[ "GO:0060079" ]
[ "GO:0007268", "GO:0060079" ]
[ "GO:0007268", "has_part GO:0060079" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0098977
98,977
inhibitory chemical synaptic transmission
biological_process
Synaptic transmission that results in an inhibitory postsynaptic potential.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0007268" ]
[ "has_part GO:0060080" ]
[ "has_part" ]
[ "GO:0060080" ]
[ "GO:0007268", "GO:0060080" ]
[ "GO:0007268", "has_part GO:0060080" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0098978
98,978
glutamatergic synapse
cellular_component
A synapse that uses glutamate as a neurotransmitter.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0045202" ]
[]
[]
[]
[ "GO:0045202" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0098979
98,979
polyadic synapse
cellular_component
A synapse consisting of a single presynapse and multiple postsynapses. These postsynapses may come from the same cell of from different cells. Polyadic synapses are common in arthropod and nematode central nervous systems.
[ "PMID:26780543" ]
null
[]
[]
[]
[]
[]
[ "GO:0045202" ]
[]
[]
[]
[ "GO:0045202" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0098980
98,980
presynaptic density
cellular_component
An electron dense specialization of the presynaptic active zone cytoskeleton.
[ "GOC:dos", "PMID:26780543" ]
null
[]
[]
[]
[]
[]
[ "GO:0048788" ]
[]
[]
[]
[ "GO:0048788" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0098981
98,981
cholinergic synapse
cellular_component
A synapse that uses acetylcholine as a neurotransmitter.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0045202" ]
[]
[]
[]
[ "GO:0045202" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0098982
98,982
GABA-ergic synapse
cellular_component
A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0045202" ]
[]
[]
[]
[ "GO:0045202" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0098983
98,983
symmetric, GABA-ergic, inhibitory synapse
cellular_component
A neuron to neuron synapse that lacks an electron dense postsynaptic specialization, uses GABA as a neurotransmitter and whose activity results in inhibitory postsynaptic potentials.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0032280", "GO:0060077", "GO:0098982" ]
[]
[]
[]
[ "GO:0032280", "GO:0060077", "GO:0098982" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0098985
98,985
asymmetric, glutamatergic, excitatory synapse
cellular_component
A neuron to neuron synapse with a postsynaptic density, that uses glutamate as a neurotransmitter and whose activity results in excitatory postsynaptic potentials.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0032279", "GO:0060076", "GO:0098978" ]
[]
[]
[]
[ "GO:0032279", "GO:0060076", "GO:0098978" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0098986
98,986
T-bar
cellular_component
A T-shaped presynpatic density. These are common in arhropod central nervous systems.
[ "GOC:dos", "PMID:26780543" ]
null
[]
[]
[]
[]
[]
[ "GO:0098980" ]
[]
[]
[]
[ "GO:0098980" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0098987
98,987
regulation of modification of synapse structure, modulating synaptic transmission
biological_process
Any process that regulates the modification of synaptic structure and as a result regulates synaptic transmission.
[ "GOC:dos" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0050804", "GO:1905244" ]
[]
[]
[]
[ "GO:0050804", "GO:1905244" ]
[ "GO:1905244", "regulates GO:0007268" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0098988
98,988
G protein-coupled glutamate receptor activity
molecular_function
Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.
[ "GOC:dos" ]
null
[ "G-protein coupled glutamate receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0004930", "GO:0008066" ]
[]
[]
[]
[ "GO:0004930", "GO:0008066" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0098989
98,989
NMDA selective glutamate receptor signaling pathway
biological_process
The series of molecular signals initiated by glutamate binding to an NMDA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription.
[ "GOC:dos", "ISBN:9780071120005" ]
null
[]
[]
[]
[]
[]
[ "GO:0035235" ]
[ "has_part GO:0004972" ]
[ "has_part" ]
[ "GO:0004972" ]
[ "GO:0004972", "GO:0035235" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0098990
98,990
AMPA selective glutamate receptor signaling pathway
biological_process
The series of molecular signals initiated by glutamate binding to an AMPA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription.
[ "GOC:dos", "ISBN:9780071120005" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0035235" ]
[ "has_part GO:0004971" ]
[ "has_part" ]
[ "GO:0004971" ]
[ "GO:0004971", "GO:0035235" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0098991
98,991
kainate selective glutamate receptor signaling pathway
biological_process
The series of molecular signals initiated by glutamate binding to an kainate-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, ending with the regulation of a downstream cellular process, e.g. transcription.
[ "GOC:signaling", "ISBN:9780071120005" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0035235" ]
[ "has_part GO:0015277" ]
[ "has_part" ]
[ "GO:0015277" ]
[ "GO:0015277", "GO:0035235" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0098992
98,992
neuronal dense core vesicle
cellular_component
A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.
[ "GOC:dos", "ISBN:978-0-07-181001-2", "Wikipedia:Neuropeptide&oldid=713905176" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0031045" ]
[]
[]
[]
[ "GO:0031045" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0098993
98,993
obsolete anchored component of synaptic vesicle membrane
cellular_component
OBSOLETE. The component of the synaptic vesicle membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
[ "GOC:dos" ]
This term was obsoleted because it represents protein topology, not a cellular component.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0030672" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]
null
null
true
true
9
GO:0098994
98,994
symbiont entry into host cell via disruption of host cell envelope
biological_process
The disruption by a symbiont of host cell envelope components to allow entry into the host cell.
[ "GOC:dos" ]
null
[ "disruption of host cell envelope during viral entry" ]
[ "EXACT" ]
[]
[]
[ "VZ:3938" ]
[ "GO:0098933" ]
[ "part_of GO:0046718" ]
[ "part_of" ]
[ "GO:0046718" ]
[ "GO:0046718", "GO:0098933" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26670\" xsd:anyURI" ]
null
null
false
true
1
GO:0098996
98,996
symbiont entry into host cell via disruption of host cell glycocalyx
biological_process
The disruption by a symbiont of host cell capsule to allow entry into the host cell.
[ "GOC:dos" ]
null
[ "catabolism of host glycocalyx during viral entry", "degradation of host capsule during virus entry", "degradation of host glycocalyx during viral entry", "disassembly of glycocalyx during viral entry", "disruption of host cell glycocalyx during viral entry", "symbiont entry into host cell by disruption o...
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "VZ:3938" ]
[ "GO:0098933" ]
[ "part_of GO:0046718" ]
[ "part_of" ]
[ "GO:0046718" ]
[ "GO:0046718", "GO:0098933" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26670\" xsd:anyURI" ]
null
null
false
true
2
GO:0098997
98,997
fusion of virus membrane with host outer membrane
biological_process
Fusion of a viral membrane with the host cell outer membrane during viral entry.
[ "GOC:dos", "VZ:3941" ]
null
[ "fusion of viral membrane with host outer membrane", "viral envelope fusion", "viral envelope fusion with host outer membrane", "viral penetration via membrane fusion", "viral-cell fusion molecule activity" ]
[ "RELATED", "BROAD", "EXACT", "BROAD", "RELATED" ]
[]
[]
[ "VZ:3941 \"Fusion of virus membrane with host cell membrane\"" ]
[ "GO:0019064" ]
[]
[]
[]
[ "GO:0019064" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0098998
98,998
extrinsic component of postsynaptic early endosome membrane
cellular_component
The component of the postsynaptic early endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
[ "GOC:autophagy", "GOC:mf" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098999" ]
[ "part_of GO:0098896" ]
[ "part_of" ]
[ "GO:0098896" ]
[ "GO:0098896", "GO:0098999" ]
[ "GO:0019898", "part_of GO:0098896" ]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0098999
98,999
extrinsic component of postsynaptic endosome membrane
cellular_component
The component of the postsynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
[ "GOC:autophagy", "GOC:mf" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0031313" ]
[ "part_of GO:0098895" ]
[ "part_of" ]
[ "GO:0098895" ]
[ "GO:0031313", "GO:0098895" ]
[ "GO:0019898", "part_of GO:0098895" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0099000
99,000
symbiont genome ejection through host cell envelope, contractile tail mechanism
biological_process
Entry of a symbiont's genome into the host cell through the host cell envelope via a contractile tail ejection system consisting of a baseplate, a central tube and an external contractile sheath. Upon binding to the host cell surface, the baseplate changes its conformation and triggers sheath contraction, driving the r...
[ "GOC:dos", "PMID:26283379", "VZ:3950" ]
null
[ "viral contractile tail ejection system", "viral genome ejection through host cell envelope, contractile tail mechanism" ]
[ "EXACT", "RELATED" ]
[]
[]
[ "VZ:3950 \"Viral contractile tail ejection system\"" ]
[ "GO:0039678" ]
[]
[]
[]
[ "GO:0039678" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26670\" xsd:anyURI" ]
null
null
false
true
5
GO:0099001
99,001
symbiont genome ejection through host cell envelope, long flexible tail mechanism
biological_process
Entry of a symbiont's genome into the host cell through the host cell envelope via a long, flexible tail ejection system consisting a baseplate, a central tube and a terminator complex which attaches the tail to the phage capsid. Upon binding to the host cell surface, the baseplate changes its conformation and triggers...
[ "GOC:dos", "PMID:22297512", "VZ:3952" ]
null
[ "viral genome ejection through host cell envelope, long flexible tail mechanism", "viral long flexible tail ejection system" ]
[ "RELATED", "EXACT" ]
[]
[]
[ "VZ:3952 \"Viral long flexible tail ejection system\"" ]
[ "GO:0039678" ]
[]
[]
[]
[ "GO:0039678" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26670\" xsd:anyURI" ]
null
null
false
true
9
GO:0099002
99,002
symbiont genome ejection through host cell envelope, short tail mechanism
biological_process
Entry of a symbiont's genome into the host cell through the host cell envelope via a short tail ejection system consisting a central tube, the connector which attaches the tail to the phage capsid and releases inner core proteins. Upon binding to the host cell surface, the phage displays a tube-like extension of its sh...
[ "GOC:dos", "PMID:22297513", "VZ:3954" ]
null
[ "viral genome ejection through host cell envelope, short tail mechanism", "viral short tail ejection system" ]
[ "RELATED", "EXACT" ]
[]
[]
[ "VZ:3954 \"Viral short tail ejection system\"" ]
[ "GO:0039678" ]
[]
[]
[]
[ "GO:0039678" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26670\" xsd:anyURI" ]
null
null
false
true
3
GO:0099003
99,003
vesicle-mediated transport in synapse
biological_process
Any vesicle-mediated transport that occurs in a synapse.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0016192" ]
[ "occurs_in GO:0045202" ]
[ "occurs_in" ]
[ "GO:0045202" ]
[ "GO:0016192", "GO:0045202" ]
[ "GO:0016192", "occurs_in GO:0045202" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0099004
99,004
obsolete calmodulin dependent kinase signaling pathway
biological_process
OBSOLETE. Any signal transduction pathway involving calmodulin dependent kinase activity.
[ "GOC:dos" ]
This term was obsoleted because it does not represent a defined siagnling pathway.
[ "CAMK signaling pathway" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0061762" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28069\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28158\" xsd:anyURI" ]
null
null
true
true
5
GO:0099005
99,005
extrinsic component of postsynaptic recycling endosome membrane
cellular_component
The component of the postsynaptic recycling endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
[ "GOC:autophagy", "GOC:mf" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098999" ]
[ "part_of GO:0098944" ]
[ "part_of" ]
[ "GO:0098944" ]
[ "GO:0098944", "GO:0098999" ]
[ "GO:0019898", "part_of GO:0098944" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0099006
99,006
symbiont entry into host cell via permeabilization of endosomal membrane
biological_process
The entry of a symbiont into a host cell, following endocytosis, via permeabilization of the endosomal membrane by membrane penetration protein(s) of the symbiont. This process mediates the entry of some non-enveloped virus into eukaryotic cells. In some cases, viral membrane-penetration protein requires to be activate...
[ "PMID:15329727", "PMID:25055856" ]
null
[ "viral entry via permeabilization of endosomal membrane" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0140267" ]
[]
[]
[]
[ "GO:0140267" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26670\" xsd:anyURI" ]
null
null
false
true
1
GO:0099007
99,007
extrinsic component of presynaptic endosome membrane
cellular_component
The component of the presynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
[ "GOC:autophagy", "GOC:mf" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0031313" ]
[ "part_of GO:0098954" ]
[ "part_of" ]
[ "GO:0098954" ]
[ "GO:0031313", "GO:0098954" ]
[ "GO:0019898", "part_of GO:0098954" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0099008
99,008
symbiont entry into host cell via permeabilization of inner membrane
biological_process
The entry of a symbiont into the cytoplasm of a host cell, following fusion with the outer membrane, via permeabilization of the plasma (inner) membrane. This process mediates the entry of some non-enveloped viruses into prokaryotic cells. In the case of some double stranded RNA viruses of prokaryotes this occurs via i...
[ "PMID:15795287", "PMID:20427561" ]
null
[ "viral entry via permeabilization of inner membrane" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0140267" ]
[]
[]
[]
[ "GO:0140267" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26670\" xsd:anyURI" ]
null
null
false
true
9
GO:0099009
99,009
viral genome circularization
biological_process
The circularization of a viral genome following infection of a host cell. This is common amongst bacterial viruses to protect the viral genome ends from nucleases, to convert the linear genome to an integrative precursor or to give rise to the replicative form of the genome. It can be mediated by covalent closure of th...
[ "PMID:11894948", "PMID:15489417", "PMID:19523475", "PMID:319596", "VZ:3968" ]
null
[]
[]
[]
[]
[ "VZ:3968 \"Viral genome circularization\"" ]
[ "GO:0016032" ]
[]
[]
[]
[ "GO:0016032" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0099010
99,010
modification of postsynaptic structure
biological_process
Any process that modifies the structure of a postsynapse.
[ "GOC:dos" ]
This class does not cover assembly or disassembly of postsynapses, only the modification/remodelling of existing ones.
[ "synapse remodelling" ]
[ "BROAD" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099563" ]
[]
[]
[]
[ "GO:0099563" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0099011
99,011
neuronal dense core vesicle exocytosis
biological_process
The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels.
[ "GOC:kmv", "PMID:17553987", "PMID:24653208" ]
null
[]
[]
[]
[]
[]
[ "GO:1990504" ]
[]
[]
[]
[ "GO:1990504" ]
[]
[]
[]
[]
[]
[]
kmv
null
false
true
2
GO:0099012
99,012
neuronal dense core vesicle membrane
cellular_component
The lipid bilayer surrounding a neuronal dense core vesicle.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0032127" ]
[ "part_of GO:0098992" ]
[ "part_of" ]
[ "GO:0098992" ]
[ "GO:0032127", "GO:0098992" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0099013
99,013
neuronal dense core vesicle lumen
cellular_component
The volume enclosed by a neuronal dense core vesicle membrane.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098898" ]
[ "part_of GO:0098992" ]
[ "part_of" ]
[ "GO:0098992" ]
[ "GO:0098898", "GO:0098992" ]
[ "GO:0060205", "part_of GO:0098992" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0099014
99,014
neuronal dense core vesicle organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0061109" ]
[]
[]
[]
[ "GO:0061109" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0099015
99,015
degradation of host chromosome by virus
biological_process
The catabolic breakdown of the DNA of a host chromosome by a virus. This occurs during infection of bacteria by some phages. It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis.
[ "PMID:163355", "PMID:335083", "PMID:3972821", "PMID:5263754", "VZ:3947" ]
null
[]
[]
[]
[]
[ "VZ:3947" ]
[ "GO:0016032" ]
[ "part_of GO:0039693" ]
[ "part_of" ]
[ "GO:0039693" ]
[ "GO:0016032", "GO:0039693" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0099016
99,016
symbiont-mediated evasion of DNA end degradation by host
biological_process
A process by which a symbiont evades and ends degradation of its DNA when free DNA ends are exposed. DNA ends are exposed during the life cycle of some viruses and these are targeted by host cells to destroy the virus. For example, some bacteriophages encode proteins that bind to free viral DNA ends, protecting them fr...
[ "GOC:dos", "PMID:11894948", "PMID:16949369", "VZ:3963" ]
null
[ "DNA end degradation evasion by virus", "evasion by virus of DNA end degradation", "evasion of DNA end degradation by host" ]
[ "EXACT", "RELATED", "EXACT" ]
[]
[]
[ "VZ:3963" ]
[ "GO:0141177" ]
[]
[]
[]
[ "GO:0141177" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23043\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26686\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27250\" xsd:anyURI" ]
null
null
false
true
7
GO:0099017
99,017
maintenance of protein localization at cell tip
biological_process
Any process in which localization of a protein is maintained at the cell tip.
[ "GOC:dos", "GOC:vw", "PMID:12894167" ]
null
[ "maintenance of protein location at cell tip" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0032507" ]
[ "occurs_in GO:0051286" ]
[ "occurs_in" ]
[ "GO:0051286" ]
[ "GO:0032507", "GO:0051286" ]
[ "GO:0045185", "occurs_in GO:0051286" ]
[]
[]
[]
[]
[]
dos
2016-06-30T15:17:41Z
false
true
9