go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0106015
106,015
negative regulation of inflammatory response to wounding
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:26022821" ]
null
[]
[]
[]
[]
[]
[ "GO:0050728", "GO:0106014", "GO:1903035" ]
[ "negatively_regulates GO:0090594" ]
[ "negatively_regulates" ]
[ "GO:0090594" ]
[ "GO:0050728", "GO:0090594", "GO:0106014", "GO:1903035" ]
[ "GO:0065007", "negatively_regulates GO:0090594" ]
[]
[]
[]
[]
[]
hjd
2017-04-28T20:09:46Z
false
true
2
GO:0106016
106,016
positive regulation of inflammatory response to wounding
biological_process
Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:26022821" ]
null
[]
[]
[]
[]
[]
[ "GO:0050729", "GO:0106014", "GO:1903036" ]
[ "positively_regulates GO:0090594" ]
[ "positively_regulates" ]
[ "GO:0090594" ]
[ "GO:0050729", "GO:0090594", "GO:0106014", "GO:1903036" ]
[ "GO:0065007", "positively_regulates GO:0090594" ]
[]
[]
[]
[]
[]
hjd
2017-04-28T20:16:31Z
false
true
1
GO:0106017
106,017
phosphatidylinositol-3,4-bisphosphate phosphatase activity
molecular_function
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.
[ "GOC:hjd" ]
null
[]
[]
[]
[]
[]
[ "GO:0034593" ]
[]
[]
[]
[ "GO:0034593" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24252\" xsd:anyURI" ]
hjd
2017-05-10T14:08:06Z
false
true
9
GO:0106018
106,018
phosphatidylinositol-3,5-bisphosphate phosphatase activity
molecular_function
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.
[ "GOC:hjd" ]
null
[]
[]
[]
[]
[]
[ "GO:0034593" ]
[]
[]
[]
[ "GO:0034593" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24252\" xsd:anyURI" ]
hjd
2017-05-10T14:19:13Z
false
true
3
GO:0106019
106,019
phosphatidylinositol-4,5-bisphosphate phosphatase activity
molecular_function
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.
[ "GOC:hjd" ]
null
[]
[]
[]
[]
[]
[ "GO:0034593" ]
[]
[]
[]
[ "GO:0034593" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24252\" xsd:anyURI" ]
hjd
2017-05-10T14:22:12Z
false
true
2
GO:0106020
106,020
regulation of vesicle docking
biological_process
Any process that modulates the frequency, rate or extent of vesicle docking.
[ "PMID:22810233" ]
null
[ "regulation of vesicle to membrane docking" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0032879", "GO:0050794" ]
[ "regulates GO:0048278" ]
[ "regulates" ]
[ "GO:0048278" ]
[ "GO:0032879", "GO:0048278", "GO:0050794" ]
[ "GO:0065007", "regulates GO:0048278" ]
[]
[]
[]
[]
[]
hjd
2017-05-16T13:58:54Z
false
true
6
GO:0106021
106,021
negative regulation of vesicle docking
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle docking.
[ "PMID:22810233" ]
null
[ "negative regulation of vesicle to membrane docking" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0048523", "GO:0051051", "GO:0106020" ]
[ "negatively_regulates GO:0048278" ]
[ "negatively_regulates" ]
[ "GO:0048278" ]
[ "GO:0048278", "GO:0048523", "GO:0051051", "GO:0106020" ]
[ "GO:0065007", "negatively_regulates GO:0048278" ]
[]
[]
[]
[]
[]
hjd
2017-05-16T14:05:29Z
false
true
8
GO:0106022
106,022
positive regulation of vesicle docking
biological_process
Any process that activates or increases the frequency, rate or extent of vesicle docking.
[ "PMID:22810233" ]
null
[ "positive regulation of vesicle to membrane docking" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0048522", "GO:0106020" ]
[ "positively_regulates GO:0048278" ]
[ "positively_regulates" ]
[ "GO:0048278" ]
[ "GO:0048278", "GO:0048522", "GO:0106020" ]
[ "GO:0065007", "positively_regulates GO:0048278" ]
[]
[]
[]
[]
[]
hjd
2017-05-16T14:12:32Z
false
true
1
GO:0106023
106,023
regulation of pupariation
biological_process
Any process that modulates the onset of pupariation.
[ "PMID:26510564" ]
null
[]
[]
[]
[]
[]
[ "GO:0048580" ]
[ "regulates GO:0035073" ]
[ "regulates" ]
[ "GO:0035073" ]
[ "GO:0035073", "GO:0048580" ]
[ "GO:0065007", "regulates GO:0035073" ]
[]
[]
[]
[]
[]
hjd
2017-05-24T19:31:39Z
false
true
7
GO:0106024
106,024
negative regulation of pupariation
biological_process
Any process that stops, prevents or reduces the rate of onset of pupariation.
[ "PMID:26510564" ]
null
[]
[]
[]
[]
[]
[ "GO:0048581", "GO:0106023" ]
[ "negatively_regulates GO:0035073" ]
[ "negatively_regulates" ]
[ "GO:0035073" ]
[ "GO:0035073", "GO:0048581", "GO:0106023" ]
[ "GO:0065007", "negatively_regulates GO:0035073" ]
[]
[]
[]
[]
[]
hjd
2017-05-24T19:35:29Z
false
true
8
GO:0106025
106,025
positive regulation of pupariation
biological_process
Any process that activates or increases the frequency, rate or extent of onset of pupariation.
[ "GOC:hjd" ]
null
[]
[]
[]
[]
[]
[ "GO:0051240", "GO:0106023" ]
[ "positively_regulates GO:0035073" ]
[ "positively_regulates" ]
[ "GO:0035073" ]
[ "GO:0035073", "GO:0051240", "GO:0106023" ]
[ "GO:0065007", "positively_regulates GO:0035073" ]
[]
[]
[]
[]
[]
hjd
2017-05-24T19:37:50Z
false
true
3
GO:0106026
106,026
Gly-tRNA(Ala) deacylase activity
molecular_function
Catalysis of the reaction: glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H+.
[ "PMID:28362257", "RHEA:53744" ]
null
[]
[]
[]
[]
[ "RHEA:53744" ]
[ "GO:0002161" ]
[]
[]
[]
[ "GO:0002161" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.1.1.96", "skos:exactMatch RHEA:53744", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29746\" xsd:anyURI" ]
hjd
2017-06-16T17:13:33Z
false
true
4
GO:0106027
106,027
neuron projection organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite.
[ "GOC:aruk", "GOC:bc", "PMID:11585923" ]
null
[]
[]
[]
[]
[]
[ "GO:0120036" ]
[]
[]
[]
[ "GO:0120036" ]
[]
[]
[]
[]
[]
[]
hjd
2017-06-23T18:30:18Z
false
true
3
GO:0106028
106,028
neuron projection retraction
biological_process
The organization process which results in the disassembly (either partial or complete) of constituent parts of a neuron projection. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
[ "GOC:aruk", "GOC:bc", "PMID:11585923" ]
null
[ "neuron projection disassembly" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0106027" ]
[]
[]
[]
[ "GO:0106027" ]
[]
[]
[]
[]
[]
[]
hjd
2017-06-23T18:32:42Z
false
true
9
GO:0106029
106,029
tRNA pseudouridine synthase activity
molecular_function
Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
[ "PMID:11095668" ]
null
[ "transfer ribonucleate pseudouridine synthetase activity", "transfer RNA pseudouridine synthetase activity", "tRNA-pseudouridine synthase activity", "tRNA-uridine isomerase activity", "tRNA-uridine uracilmutase activity" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "RHEA:42964", "RHEA:54572", "RHEA:57876", "RHEA:60556" ]
[ "GO:0009982", "GO:0140101" ]
[]
[]
[]
[ "GO:0009982", "GO:0140101" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:54572", "skos:narrowMatch RHEA:42964", "skos:narrowMatch RHEA:57876", "skos:narrowMatch RHEA:60556", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26797\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI...
hjd
2017-06-26T17:37:30Z
false
true
4
GO:0106030
106,030
neuron projection fasciculation
biological_process
The collection of neuronal projections into a bundle of rods, known as a fascicle.
[ "GOC:aruk", "GOC:bc.", "PMID:12761826" ]
null
[]
[]
[]
[]
[]
[ "GO:0031175" ]
[]
[]
[]
[ "GO:0031175" ]
[]
[]
[]
[]
[]
[]
hjd
2017-06-26T19:43:23Z
false
true
4
GO:0106032
106,032
snRNA pseudouridine synthase activity
molecular_function
Catalysis of the reaction: uridine in snRNA = pseudouridine in snRNA. Conversion of uridine in an snRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
[ "PMID:28432181", "RHEA:51124" ]
null
[]
[]
[]
[]
[ "RHEA:51124" ]
[ "GO:0009982", "GO:0140098" ]
[]
[]
[]
[ "GO:0009982", "GO:0140098" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:51124", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26618\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
hjd
2017-06-28T17:44:20Z
false
true
4
GO:0106034
106,034
obsolete protein maturation by [2Fe-2S] cluster transfer
biological_process
OBSOLETE. The transfer of an assembled [2Fe-2S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
[ "PMID:23615440" ]
The reason for obsoletion is that these BP terms represent MFs.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0051604" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29105\" xsd:anyURI" ]
hjd
2017-07-07T17:24:59Z
true
true
2
GO:0106035
106,035
obsolete protein maturation by [4Fe-4S] cluster transfer
biological_process
OBSOLETE. The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
[ "PMID:23615440" ]
The reason for obsoletion is that these BP terms represent MFs.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0051604" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29105\" xsd:anyURI" ]
hjd
2017-07-07T17:26:10Z
true
true
6
GO:0106036
106,036
assembly of apicomedial cortex actomyosin
biological_process
A process which results in the assembly or arrangement of constituent parts apicomedial cortex actomyosin.
[ "PMID:28263180" ]
null
[]
[]
[]
[]
[]
[ "GO:0030866", "GO:0031032" ]
[]
[]
[]
[ "GO:0030866", "GO:0031032" ]
[]
[]
[]
[]
[]
[]
hjd
2017-07-12T16:57:06Z
false
true
6
GO:0106037
106,037
apicomedial cortex
cellular_component
The region that lies just beneath the plasma membrane in the middle of the apical edge of a cell.
[ "PMID:23831726", "PMID:28263180" ]
null
[ "medioapical cortex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0099738" ]
[ "part_of GO:0045179" ]
[ "part_of" ]
[ "GO:0045179" ]
[ "GO:0045179", "GO:0099738" ]
[]
[]
[]
[]
[]
[]
hjd
2017-07-12T16:59:52Z
false
true
4
GO:0106038
106,038
obsolete vesicle assembly
biological_process
OBSOLETE. A process carried out at the cellular level, which results in the arrangement of constituent parts of a vesicle. Vesicle assembly begins with membrane bending (GO:0097753) and ends with fusion of the vesicle after vesicle scission (GO:0099050).
[ "GOC:aruk", "GOC:bc", "PMID:25898166" ]
This term was made obsolete because it is an exact synonym of 'membrane budding'.
[ "vesicle biosynthesis", "vesicle formation" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
hjd
2017-07-17T13:52:28Z
true
true
6
GO:0106039
106,039
obsolete vesicle fusion involved in vesicle assembly
biological_process
OBSOLETE. A process carried out at the cellular level, which is the final step in vesicle assembly. Vesicle fusion occurs when a newly assembled vesicle closes up, following vesicle vesicle scission (GO:0099050).
[ "GOC:aruk", "GOC:bc", "PMID:25898166" ]
This term was made obsolete becausethat 'fusion' should only be used for two membranes getting joined together, whereas in this case it would be one membrane 'closing/sealing up'.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
hjd
2017-07-17T13:56:31Z
true
true
3
GO:0106040
106,040
regulation of GABA-A receptor activity
biological_process
Any process that modulates the frequency, rate or extent of GABA-A receptor activity.
[ "PMID:24044036" ]
null
[]
[]
[]
[ "gocheck_obsoletion_candidate" ]
[]
[ "GO:0010469" ]
[ "regulates GO:0004890" ]
[ "regulates" ]
[ "GO:0004890" ]
[ "GO:0004890", "GO:0010469" ]
[ "GO:0065007", "regulates GO:0004890" ]
[]
[]
[]
[]
[]
hjd
2017-07-27T18:47:02Z
false
true
6
GO:0106041
106,041
obsolete positive regulation of GABA-A receptor activity
biological_process
OBSOLETE. Any process that activates or increases the frequency, rate or extent of GABA-A receptor activity.
[ "PMID:24044036" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28482\" xsd:anyURI" ]
hjd
2017-07-27T18:51:30Z
true
true
5
GO:0106042
106,042
obsolete negative regulation of GABA-A receptor activity
biological_process
OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of GABA-A receptor activity.
[ "PMID:24044036" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28482\" xsd:anyURI" ]
hjd
2017-07-27T18:55:03Z
true
true
9
GO:0106044
106,044
guanine deglycation
biological_process
The removal of a sugar or dicarbonyl from a glycated guanine.
[ "PMID:28596309" ]
null
[]
[]
[]
[]
[]
[ "GO:0006281" ]
[]
[]
[]
[ "GO:0006281" ]
[]
[]
[]
[]
[]
[]
hjd
2017-08-01T18:15:28Z
false
true
5
GO:0106045
106,045
obsolete guanine deglycation, methylglyoxal removal
biological_process
OBSOLETE. The removal of methylglyoxal from a glycated guanine, to form lactate and a deglycated guanine.
[ "PMID:28596309" ]
The reason for obsoletion is that this term represents a molecular function rather than a biological process.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0036524" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31367\" xsd:anyURI" ]
null
null
true
true
5
GO:0106047
106,047
polyamine deacetylation
biological_process
The modification of acetylpolyamine by the removal of acetyl groups.
[ "PMID:28516954" ]
null
[]
[]
[]
[]
[]
[ "GO:0006595", "GO:0098732" ]
[]
[]
[]
[ "GO:0006595", "GO:0098732" ]
[]
[]
[]
[]
[]
[]
hjd
2017-08-01T18:36:46Z
false
true
5
GO:0106049
106,049
regulation of cellular response to osmotic stress
biological_process
Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress.
[ "PMID:10398679" ]
null
[]
[]
[]
[]
[]
[ "GO:0047484", "GO:0080135" ]
[ "regulates GO:0071470" ]
[ "regulates" ]
[ "GO:0071470" ]
[ "GO:0047484", "GO:0071470", "GO:0080135" ]
[ "GO:0065007", "regulates GO:0071470" ]
[]
[]
[]
[]
[]
hjd
2017-08-04T14:53:47Z
false
true
9
GO:0106050
106,050
obsolete tRNA 2'-O-methyltransferase activity
molecular_function
OBSOLETE. Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide.
[ "PMID:17242307" ]
This term was obsoleted because it is an unnecessray grouping term.
[]
[]
[]
[]
[ "Reactome:R-HSA-6788668 \"TRMT13 2'-O-methylates adenosine-4 in tRNA\"", "Reactome:R-HSA-6788684 \"TRMT13 2'-O-methylates cytidine-4 in tRNA\"", "Reactome:R-HSA-9024159 \"FTSJ1 2'-O-methylates cytidine-32 in tRNA(Phe)\"" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0106339", "GO:0106340" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31519\" xsd:anyURI" ]
hjd
2017-08-11T20:30:31Z
true
true
8
GO:0106054
106,054
obsolete tRNA-uracil-34 sulfurtransferase activity
molecular_function
OBSOLETE. Catalysis of the reaction: uridine34 in tRNA + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 2-thiouridine34 in tRNA + a [TusE sulfur carrier protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+.
[ "PMID:12549933", "PMID:16387657" ]
The reason for obsoletion is that this term is equivalent to GO:0103016 tRNA-uridine 2-sulfurtransferase activity.
[ "tRNA U34 2-thiouridylase", "tRNA U34 thiol-transferase activity", "tRNA-specific 2-thiouridylase" ]
[ "EXACT", "EXACT", "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0103016" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13257\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27928\" xsd:anyURI" ]
hjd
2017-09-05T19:10:12Z
true
true
6
GO:0106055
106,055
mannosyl-oligosaccharide 1,2-alpha-mannosidase complex
cellular_component
A protein complex capable of catalysing the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.
[ "GOC:bhm", "PMID:21700223" ]
An example is MNL1 (P38888) in Saccharomyces cerevisiae. PMID:19124653 (by physical interaction evidence).
[]
[]
[]
[]
[]
[ "GO:0140534", "GO:1902494" ]
[ "part_of GO:0005788" ]
[ "part_of" ]
[ "GO:0005788" ]
[ "GO:0005788", "GO:0140534", "GO:1902494" ]
[]
[]
[]
[]
[]
[]
hjd
2017-09-14T15:23:28Z
false
true
4
GO:0106056
106,056
regulation of calcineurin-mediated signaling
biological_process
Any process that modulates the frequency, rate or extent of calcineurin-mediated signaling.
[ "PMID:25081204" ]
null
[]
[]
[]
[]
[]
[ "GO:0050848" ]
[ "regulates GO:0097720" ]
[ "regulates" ]
[ "GO:0097720" ]
[ "GO:0050848", "GO:0097720" ]
[ "GO:0065007", "regulates GO:0097720" ]
[]
[]
[]
[]
[]
hjd
2017-09-18T16:44:05Z
false
true
8
GO:0106057
106,057
negative regulation of calcineurin-mediated signaling
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated signaling.
[ "PMID:25081204" ]
null
[]
[]
[]
[]
[]
[ "GO:0050849", "GO:0106056" ]
[ "negatively_regulates GO:0097720" ]
[ "negatively_regulates" ]
[ "GO:0097720" ]
[ "GO:0050849", "GO:0097720", "GO:0106056" ]
[ "GO:0065007", "negatively_regulates GO:0097720" ]
[]
[]
[]
[]
[]
hjd
2017-09-18T16:50:11Z
false
true
8
GO:0106058
106,058
positive regulation of calcineurin-mediated signaling
biological_process
Any process that activates or increases the frequency, rate or extent of calcineurin-mediated signaling.
[ "PMID:25081204" ]
null
[]
[]
[]
[]
[]
[ "GO:0050850", "GO:0106056" ]
[ "positively_regulates GO:0097720" ]
[ "positively_regulates" ]
[ "GO:0097720" ]
[ "GO:0050850", "GO:0097720", "GO:0106056" ]
[ "GO:0065007", "positively_regulates GO:0097720" ]
[]
[]
[]
[]
[]
hjd
2017-09-18T16:57:06Z
false
true
2
GO:0106059
106,059
tRNA (cytidine(56)-2'-O-ribose)-methyltransferase activity
molecular_function
Catalysis of the reaction: S-adenosyl-L-methionine + cytidine56 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine56 in tRNA.
[ "RHEA:42968" ]
null
[ "tRNA (cytidine 56-2'-O)-methyltransferase activity", "tRNA (cytidine(56)-2'-O)-methyltransferase activity" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "EC:2.1.1.206", "MetaCyc:RXN-11869", "RHEA:42968" ]
[ "GO:0016427" ]
[]
[]
[]
[ "GO:0016427" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.1.1.206", "skos:exactMatch RHEA:42968", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24771\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26018\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-onto...
hjd
2017-10-05T19:02:22Z
false
true
4
GO:0106061
106,061
negative regulation of exit from meiosis
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of exit from meiosis.
[ "GOC:al", "PMID:11493649" ]
null
[]
[]
[]
[]
[]
[ "GO:0106060", "GO:1901994" ]
[ "negatively_regulates GO:1990947" ]
[ "negatively_regulates" ]
[ "GO:1990947" ]
[ "GO:0106060", "GO:1901994", "GO:1990947" ]
[ "GO:0065007", "negatively_regulates GO:1990947" ]
[]
[]
[]
[]
[]
hjd
2017-10-18T16:51:15Z
false
true
5
GO:0106063
106,063
G protein-coupled folate receptor activity
molecular_function
Combining with folate and transmitting the signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.
[ "PMID:26906738" ]
null
[ "G-protein coupled folate receptor activity", "G-protein coupled folic acid receptor activity" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0004930" ]
[]
[]
[]
[ "GO:0004930" ]
[]
[]
[]
[]
[]
[]
hjd
2017-10-27T17:10:07Z
false
true
6
GO:0106064
106,064
regulation of cobalamin metabolic process
biological_process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
[ "PMID:29056341" ]
null
[]
[]
[]
[]
[]
[ "GO:1901401" ]
[ "regulates GO:0009235" ]
[ "regulates" ]
[ "GO:0009235" ]
[ "GO:0009235", "GO:1901401" ]
[ "GO:0065007", "regulates GO:0009235" ]
[]
[]
[]
[]
[]
hjd
2017-10-27T17:33:05Z
false
true
8
GO:0106068
106,068
SUMO ligase complex
cellular_component
A protein ligase complex that enables protein sumoylation. Consists of a SUMO-protein transferase and other proteins that may confer substrate specificity of the complex.
[ "PMID:16847351" ]
null
[ "SUMO transferase complex", "SUMO-protein ligase complex", "Sumoylation complex" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1990234" ]
[]
[]
[]
[ "GO:1990234" ]
[]
[]
[]
[]
[]
[]
hjd
2017-11-22T18:46:00Z
false
true
6
GO:0106069
106,069
synapsis initiation complex
cellular_component
A SUMO-E3 ligase complex capable of promoting synapsis, the meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase.
[ "PMID:16847351" ]
null
[]
[]
[]
[]
[]
[ "GO:0106068", "GO:0140513" ]
[ "part_of GO:0000794" ]
[ "part_of" ]
[ "GO:0000794" ]
[ "GO:0000794", "GO:0106068", "GO:0140513" ]
[]
[]
[]
[]
[]
[]
hjd
2017-11-22T18:50:26Z
false
true
3
GO:0106070
106,070
regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
biological_process
Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.
[ "GOC:hjd", "PMID:19246489" ]
null
[ "regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0008277" ]
[ "regulates GO:0007189" ]
[ "regulates" ]
[ "GO:0007189" ]
[ "GO:0007189", "GO:0008277" ]
[ "GO:0065007", "regulates GO:0007189" ]
[]
[]
[]
[]
[]
hjd
2017-11-28T18:28:22Z
false
true
7
GO:0106071
106,071
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
biological_process
Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.
[ "GOC:hjd", "PMID:19246489" ]
null
[ "positive regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0045745", "GO:0106070" ]
[ "positively_regulates GO:0007189" ]
[ "positively_regulates" ]
[ "GO:0007189" ]
[ "GO:0007189", "GO:0045745", "GO:0106070" ]
[ "GO:0065007", "positively_regulates GO:0007189" ]
[]
[]
[]
[]
[]
hjd
2017-11-28T18:38:52Z
false
true
4
GO:0106072
106,072
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.
[ "GOC:hjd", "PMID:19246489" ]
null
[ "negative regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0045744", "GO:0106070" ]
[ "negatively_regulates GO:0007189" ]
[ "negatively_regulates" ]
[ "GO:0007189" ]
[ "GO:0007189", "GO:0045744", "GO:0106070" ]
[ "GO:0065007", "negatively_regulates GO:0007189" ]
[]
[]
[]
[]
[]
hjd
2017-11-28T18:41:31Z
false
true
5
GO:0106073
106,073
dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity
molecular_function
Catalysis of the addition of the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
[ "GOC:ha", "PMID:9597543" ]
null
[]
[]
[]
[]
[ "EC:2.4.1.256", "MetaCyc:RXN-5472", "RHEA:29543" ]
[ "GO:0004583" ]
[]
[]
[]
[ "GO:0004583" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.4.1.256", "skos:exactMatch RHEA:29543", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28029\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
hjd
2017-11-28T19:16:37Z
false
true
9
GO:0106074
106,074
aminoacyl-tRNA metabolism involved in translational fidelity
biological_process
Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation.
[ "GOC:hjd" ]
null
[ "aminoacyl-tRNA correction", "aminoacyl-tRNA editin", "aminoacyl-tRNA proofreading" ]
[ "RELATED", "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0006399", "GO:0006450" ]
[]
[]
[]
[ "GO:0006399", "GO:0006450" ]
[]
[]
[]
[]
[]
[]
hjd
2017-11-29T17:48:39Z
false
true
8
GO:0106075
106,075
peptide N-succinyltransferase activity
molecular_function
Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: succinyl-CoA + peptide = CoA + N-succinylpeptide.
[ "PMID:29211711" ]
null
[]
[]
[]
[]
[]
[ "GO:0016410" ]
[]
[]
[]
[ "GO:0016410" ]
[]
[]
[]
[]
[]
[]
hjd
2017-12-15T18:23:58Z
false
true
7
GO:0106076
106,076
peptide-lysine-N-succinyltransferase activity
molecular_function
Catalysis of the reaction: succinyl-CoA + lysine in peptide = CoA + N-succinyl-lysine-peptide.
[ "PMID:29211711" ]
null
[]
[]
[]
[]
[]
[ "GO:0106075" ]
[]
[]
[]
[ "GO:0106075" ]
[]
[]
[]
[]
[]
[]
hjd
2017-12-15T18:25:16Z
false
true
5
GO:0106077
106,077
obsolete histone succinylation
biological_process
OBSOLETE. The modification of a histone by the addition of an succinyl group.
[ "PMID:29211711" ]
The reason for obsoletion is that this term represents a Molecular Function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27014\" xsd:anyURI" ]
hjd
2017-12-15T18:27:16Z
true
true
9
GO:0106078
106,078
histone succinyltransferase activity
molecular_function
Catalysis of the reaction: succinyl-CoA + histone = CoA + succinyl-histone.
[ "PMID:29211711" ]
null
[]
[]
[]
[]
[]
[ "GO:0106075", "GO:0140993" ]
[]
[]
[]
[ "GO:0106075", "GO:0140993" ]
[]
[]
[]
[]
[]
[]
hjd
2017-12-15T18:29:40Z
false
true
5
GO:0106080
106,080
GATOR1 complex binding
molecular_function
Binding to a GATOR1 complex.
[ "PMID:28199306" ]
null
[]
[]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[]
[]
[]
hjd
2017-12-22T14:49:54Z
false
true
6
GO:0106081
106,081
maltose import across plasma membrane
biological_process
The directed movement of maltose from outside of a cell, across the plasma membrane and into the cytosol.
[ "PMID:11136464" ]
null
[]
[]
[]
[]
[]
[ "GO:0098704", "GO:1904981" ]
[]
[]
[]
[ "GO:0098704", "GO:1904981" ]
[]
[]
[]
[]
[]
[]
hjd
2017-12-28T18:14:16Z
false
true
5
GO:0106082
106,082
sucrose import across plasma membrane
biological_process
The directed movement of sucrose from outside of a cell, across the plasma membrane and into the cytosol.
[ "PMID:11136464" ]
null
[]
[]
[]
[]
[]
[ "GO:0098704", "GO:1904982" ]
[]
[]
[]
[ "GO:0098704", "GO:1904982" ]
[]
[]
[]
[]
[]
[]
hjd
2017-12-28T18:16:29Z
false
true
3
GO:0106083
106,083
nuclear membrane protein complex
cellular_component
Any protein complex that is part of the nuclear membrane.
[ "GOC:lnp", "PMID:28356353" ]
null
[]
[]
[]
[]
[]
[ "GO:0098796", "GO:0140513" ]
[ "part_of GO:0005635" ]
[ "part_of" ]
[ "GO:0005635" ]
[ "GO:0005635", "GO:0098796", "GO:0140513" ]
[]
[]
[]
[]
[]
[]
hjd
2018-01-05T19:51:26Z
false
true
8
GO:0106084
106,084
mitotic nuclear membrane microtubule tethering complex
cellular_component
A protein complex capable of interacting with the spindle pole body and the nuclear envelope, in order to embed the spindle pole body in the nuclear envelope at fusion sites of the inner and outer nuclear membrane.
[ "GOC:lnp", "PMID:28356353" ]
In S. cerevisae Mps2-Bpb1 is the membrane anchor sub complex and Spc29 is the spindle pole body linker molecule.
[ "Mps2-Bbp1-Spc29 complex", "nuclear membrane mitotic spindle pole body tethering complex" ]
[ "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0106094" ]
[]
[]
[]
[ "GO:0106094" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14829\" xsd:anyURI" ]
hjd
2018-01-05T19:55:37Z
false
true
2
GO:0106088
106,088
obsolete regulation of cell adhesion involved in sprouting angiogenesis
biological_process
OBSOLETE. Any process that modulates the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:24177325" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31330\" xsd:anyURI" ]
hjd
2018-01-22T18:24:12Z
true
true
7
GO:0106089
106,089
negative regulation of cell adhesion involved in sprouting angiogenesis
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:24177325" ]
null
[]
[]
[]
[]
[]
[ "GO:0007162", "GO:1903671" ]
[ "negatively_regulates GO:0120078" ]
[ "negatively_regulates" ]
[ "GO:0120078" ]
[ "GO:0007162", "GO:0120078", "GO:1903671" ]
[ "GO:0065007", "negatively_regulates GO:0120078" ]
[]
[]
[]
[]
[]
hjd
2018-01-22T18:28:08Z
false
true
9
GO:0106092
106,092
obsolete glial cell projection elongation involved in axon ensheathment
biological_process
OBSOLETE. The extension of a glial cell process or projection to wrap around an axon.
[ "GOC:ha", "PMID:27131624" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]
hjd
2018-01-26T19:43:00Z
true
true
8
GO:0106093
106,093
EDS1 disease-resistance complex
cellular_component
A plant complex involved in basal disease resistance and resistance (R) gene-mediated effector triggered immunity (ETI). Regulates accumulation of the hormone salicylic acid (SA) which is a necessary component of systemic immunity. Involved in responds to bacteria, viruses and oomycetes.
[ "GOC:bhm", "PMID:11574472", "PMID:16040633" ]
Interacts with the R genes triggering ETI and systemic resistance.
[ "EDS1-PAD4 complex", "EDS1-PAD4-SAG101 complex", "EDS1-SAG101 complex" ]
[ "NARROW", "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[]
[]
[]
hjd
2018-01-29T20:02:47Z
false
true
5
GO:0106094
106,094
nuclear membrane microtubule tethering complex
cellular_component
A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links thereby links the nuclear lumen to cytoplasmic microtubules.
[ "GOC:vw", "PMID:19225124" ]
null
[]
[]
[]
[]
[]
[ "GO:0106083" ]
[]
[]
[]
[ "GO:0106083" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14829\" xsd:anyURI" ]
hjd
2018-02-02T18:58:35Z
false
true
3
GO:0106095
106,095
m7G(5')pppN diphosphatase complex
cellular_component
A homodimeric protein complex that catalyzes the reaction: 7-methylguanosine-5'-triphospho-5'-pholynucleotide + H20 = 7-methylguanosine-5'-phosphate + polynucleotide.
[ "GOC:lnp", "PMID:22985415", "PMID:26258763" ]
null
[ "7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase enzyme", "DCS1 decapping scavenger complex", "M(7)G(5')pppN pyrophosphatase enzyme", "m7G(5')pppN diphosphatase enzyme", "m7G(5')pppN pyrophosphatase enzyme" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1903293" ]
[]
[]
[]
[ "GO:1903293" ]
[]
[]
[]
[]
[]
[]
hjd
2018-02-07T17:52:03Z
false
true
4
GO:0106096
106,096
response to ceramide
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus.
[ "PMID:18006463" ]
null
[]
[]
[]
[]
[]
[ "GO:0033993" ]
[]
[]
[]
[ "GO:0033993" ]
[]
[]
[]
[]
[]
[]
hjd
2018-02-12T19:48:43Z
false
true
5
GO:0106097
106,097
cellular response to ceramide
biological_process
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus.
[ "PMID:18006463" ]
null
[]
[]
[]
[]
[]
[ "GO:0071396" ]
[]
[]
[]
[ "GO:0071396" ]
[]
[]
[]
[]
[]
[]
hjd
2018-02-12T19:52:55Z
false
true
2
GO:0106098
106,098
NAGS/NAGK complex
cellular_component
A protein complex that acts both as N-acetylglutamate synthase (NAGS) catalysing the production of N-Acetylglutamate from glutamate and acetyl-CoA, and as N-acetylglutamate kinase (NAGK) catalysing the reaction ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate.
[ "GOC:lnp", "PMID:11553611" ]
null
[]
[]
[]
[]
[]
[ "GO:0031248", "GO:0061695", "GO:0098798" ]
[ "part_of GO:0005759" ]
[ "part_of" ]
[ "GO:0005759" ]
[ "GO:0005759", "GO:0031248", "GO:0061695", "GO:0098798" ]
[]
[]
[]
[]
[]
[]
hjd
2018-02-15T00:22:31Z
false
true
3
GO:0106099
106,099
2-keto-3-deoxy-L-rhamnonate aldolase activity
molecular_function
Catalysis of the reaction 2-dehydro-3-deoxy-L-rhamnonate = pyruvate + (S)-lactaldehyde.
[ "EC:4.1.2.53", "GOC:imk", "PMID:18754683" ]
null
[]
[]
[]
[]
[ "EC:4.1.2.53", "RHEA:25784" ]
[ "GO:0016832" ]
[]
[]
[]
[ "GO:0016832" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:4.1.2.53", "skos:exactMatch RHEA:25784", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
hjd
2018-02-15T16:12:17Z
false
true
4
GO:0106100
106,100
beta-pinacene synthase activity
molecular_function
Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate = beta-pinacene + diphosphate.
[ "PMID:28696553", "RHEA:58172" ]
null
[]
[]
[]
[]
[ "EC:4.2.3.200", "MetaCyc:RXN-20045", "RHEA:58172" ]
[ "GO:0010333" ]
[]
[]
[]
[ "GO:0010333" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:4.2.3.200", "skos:exactMatch MetaCyc:RXN-20045", "skos:exactMatch RHEA:58172", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30910\" xsd:anyURI" ]
hjd
2018-02-15T16:51:59Z
false
true
8
GO:0106101
106,101
ER-dependent peroxisome localization
biological_process
A process in which a protein is transported to, or maintained at, a location in a peroxisome via the endoplasmic reticulum.
[ "GOC:pga", "PMID:19479899", "PMID:26408931" ]
null
[]
[]
[]
[]
[]
[ "GO:0072662" ]
[]
[]
[]
[ "GO:0072662" ]
[]
[]
[]
[]
[]
[]
hjd
2018-02-15T17:54:20Z
false
true
2
GO:0106103
106,103
COPII vesicles tethering complex
cellular_component
A protein complex that resides in the cis-golgi membrane and plays a role in the tethering of COPII vesicles, through an interaction with vesicle tethering proteins (p115 in H. Sapiens and Uso1 S. cerevisiae), granting the cis-Golgi and endoplasmic reticulum to Golgi vesicle-mediated transport. It is composed by GRASP6...
[ "GOC:lnp", "PMID:21482742", "PMID:9628863" ]
null
[ "Bug1-Grh1 complex", "GRASP65-GM130 complex" ]
[ "NARROW", "EXACT" ]
[]
[]
[]
[ "GO:0098796", "GO:0099023" ]
[ "part_of GO:0033106" ]
[ "part_of" ]
[ "GO:0033106" ]
[ "GO:0033106", "GO:0098796", "GO:0099023" ]
[]
[]
[]
[]
[]
[]
hjd
2018-02-15T23:36:12Z
false
true
6
GO:0106104
106,104
regulation of glutamate receptor clustering
biological_process
Any process that modulates the frequency, rate or extent of glutamate receptor clustering.
[ "GOC:ha", "PMID:28455372" ]
null
[]
[]
[]
[]
[]
[ "GO:1903909" ]
[ "regulates GO:0097688" ]
[ "regulates" ]
[ "GO:0097688" ]
[ "GO:0097688", "GO:1903909" ]
[ "GO:0065007", "regulates GO:0097688" ]
[]
[]
[]
[]
[]
hjd
2018-03-06T15:54:33Z
false
true
3
GO:0106105
106,105
Ala-tRNA(Thr) deacylase activity
molecular_function
Catalysis of the reaction: L-alanyl-tRNA(Thr) + H2O = tRNA(Thr) + L-alanine + H+.
[ "PMID:29410408", "RHEA:17793" ]
null
[ "L-alanyl-tRNA(Thr) deacylase" ]
[ "EXACT" ]
[]
[]
[ "RHEA:17793" ]
[ "GO:0002161" ]
[]
[]
[]
[ "GO:0002161" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:17793", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29746\" xsd:anyURI" ]
hjd
2018-03-14T22:03:29Z
false
true
9
GO:0106106
106,106
cold-induced thermogenesis
biological_process
The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature.
[ "PMID:27876809" ]
null
[ "CIT" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:1990845" ]
[]
[]
[]
[ "GO:1990845" ]
[]
[]
[]
[]
[]
[]
hjd
2018-03-21T20:30:52Z
false
true
7
GO:0106107
106,107
regulation of (R)-mevalonic acid biosynthetic process
biological_process
Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:24296663" ]
null
[]
[]
[]
[]
[]
[ "GO:0009889", "GO:0062012" ]
[ "regulates GO:1901737" ]
[ "regulates" ]
[ "GO:1901737" ]
[ "GO:0009889", "GO:0062012", "GO:1901737" ]
[ "GO:0065007", "regulates GO:1901737" ]
[]
[]
[]
[]
[]
hjd
2018-03-27T14:08:59Z
false
true
6
GO:0106108
106,108
negative regulation of (R)-mevalonic acid biosynthetic process
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:24296663" ]
null
[]
[]
[]
[]
[]
[ "GO:0009890", "GO:0062014", "GO:0106107" ]
[ "negatively_regulates GO:1901737" ]
[ "negatively_regulates" ]
[ "GO:1901737" ]
[ "GO:0009890", "GO:0062014", "GO:0106107", "GO:1901737" ]
[ "GO:0065007", "negatively_regulates GO:1901737" ]
[]
[]
[]
[]
[]
hjd
2018-03-27T14:15:55Z
false
true
9
GO:0106109
106,109
positive regulation of (R)-mevalonic acid biosynthetic process
biological_process
Any process that activates or increases the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:24296663" ]
null
[]
[]
[]
[]
[]
[ "GO:0009891", "GO:0062013", "GO:0106107" ]
[ "positively_regulates GO:1901737" ]
[ "positively_regulates" ]
[ "GO:1901737" ]
[ "GO:0009891", "GO:0062013", "GO:0106107", "GO:1901737" ]
[ "GO:0065007", "positively_regulates GO:1901737" ]
[]
[]
[]
[]
[]
hjd
2018-03-27T14:20:47Z
false
true
7
GO:0106110
106,110
vomitoxin biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, also known as deoxynivalenol, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats.
[ "https://doi.org/10.1007/BF03356188", "PMID:19333439", "PMID:25680507", "PMID:25758923", "PMID:8637056" ]
null
[ "deoxynivalenol biosynthetic process", "DON biosynthetic process", "vomitoxin anabolism", "vomitoxin biosynthesis", "vomitoxin formation", "vomitoxin synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0016106", "GO:0034309", "GO:0042181", "GO:0043386", "GO:0046173", "GO:0097176", "GO:0120255", "GO:1901503", "GO:1902653" ]
[]
[]
[]
[ "GO:0016106", "GO:0034309", "GO:0042181", "GO:0043386", "GO:0046173", "GO:0097176", "GO:0120255", "GO:1901503", "GO:1902653" ]
[]
[]
[]
[]
[]
[]
hjd
2018-04-16T19:06:06Z
false
true
2
GO:0106111
106,111
obsolete regulation of mitotic cohesin ssDNA (lagging strand) loading
biological_process
OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.
[ "PMID:29358048" ]
The reason for obsoletion is that this term represents the regulation of a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23400\" xsd:anyURI" ]
hjd
2018-04-18T14:36:47Z
true
true
8
GO:0106112
106,112
obsolete negative regulation of mitotic cohesin ssDNA (lagging strand) loading
biological_process
OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.
[ "PMID:29358048" ]
The reason for obsoletion is that this term represents the regulation of a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23400\" xsd:anyURI" ]
hjd
2018-04-18T14:41:50Z
true
true
1
GO:0106113
106,113
obsolete positive regulation of mitotic cohesin ssDNA (lagging strand) loading
biological_process
OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.
[ "PMID:29358048" ]
The reason for obsoletion is that this term represents the regulation of a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23400\" xsd:anyURI" ]
hjd
2018-04-18T14:46:03Z
true
true
3
GO:0106114
106,114
obsolete regulation of mitotic cohesin dsDNA (leading strand) loading
biological_process
OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.
[ "PMID:29358048" ]
The reason for obsoletion is that this term represents the regulation of a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23400\" xsd:anyURI" ]
hjd
2018-04-18T14:48:13Z
true
true
3
GO:0106116
106,116
obsolete positive regulation of mitotic cohesin dsDNA (leading strand) loading
biological_process
OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.
[ "PMID:29358048" ]
The reason for obsoletion is that this term represents the regulation of a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23400\" xsd:anyURI" ]
hjd
2018-04-18T14:52:21Z
true
true
4
GO:0106117
106,117
acidocalcisome organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an acidocalcisome. An acidocalcisome is an electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cati...
[ "GO:0020022", "PMID:25964650", "PMID:26523947" ]
null
[ "acidocalcisome biogenesis", "acidocalcisome organisation", "acidocalcisome organization and biogenesis", "metachromatic granule organization", "polyphosphate vacuole organization", "volutin granule organization" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0006996" ]
[]
[]
[]
[ "GO:0006996" ]
[]
[]
[]
[]
[]
[]
hjd
2018-04-19T17:18:01Z
false
true
4
GO:0106118
106,118
regulation of sterol biosynthetic process
biological_process
Any process that modulates the frequency, rate or extent of a sterol biosynthetic process.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:16459310" ]
null
[]
[]
[]
[]
[]
[ "GO:0050810" ]
[ "regulates GO:0016126" ]
[ "regulates" ]
[ "GO:0016126" ]
[ "GO:0016126", "GO:0050810" ]
[ "GO:0065007", "regulates GO:0016126" ]
[]
[]
[]
[]
[]
hjd
2018-04-19T17:41:06Z
false
true
2
GO:0106119
106,119
negative regulation of sterol biosynthetic process
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of a sterol biosynthetic process.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:16459310" ]
null
[]
[]
[]
[]
[]
[ "GO:0010894", "GO:0106118" ]
[ "negatively_regulates GO:0016126" ]
[ "negatively_regulates" ]
[ "GO:0016126" ]
[ "GO:0010894", "GO:0016126", "GO:0106118" ]
[ "GO:0065007", "negatively_regulates GO:0016126" ]
[]
[]
[]
[]
[]
hjd
2018-04-19T17:44:46Z
false
true
5
GO:0106121
106,121
positive regulation of cobalamin metabolic process
biological_process
Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process.
[ "PMID:29056341" ]
null
[]
[]
[]
[]
[]
[ "GO:0009893", "GO:0106064" ]
[ "positively_regulates GO:0009235" ]
[ "positively_regulates" ]
[ "GO:0009235" ]
[ "GO:0009235", "GO:0009893", "GO:0106064" ]
[ "GO:0065007", "positively_regulates GO:0009235" ]
[]
[]
[]
[]
[]
hjd
2018-05-01T18:07:12Z
false
true
4
GO:0106122
106,122
negative regulation of cobalamin metabolic process
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process.
[ "PMID:29056341" ]
null
[]
[]
[]
[]
[]
[ "GO:0009892", "GO:0106064" ]
[ "negatively_regulates GO:0009235" ]
[ "negatively_regulates" ]
[ "GO:0009235" ]
[ "GO:0009235", "GO:0009892", "GO:0106064" ]
[ "GO:0065007", "negatively_regulates GO:0009235" ]
[]
[]
[]
[]
[]
hjd
2018-05-01T18:12:48Z
false
true
6
GO:0106123
106,123
reservosome
cellular_component
A large membrane-bound endocytic organelle present only in members of the Schizotrypanum subgenus of the Trypanosoma genus and is defined as the site of storage of endocytosed macromolecules and lysosomal enzymes. It is found at the posterior end of epimastigote forms of Trypanosoma cruzi, but absent in amastigotes and...
[ "GOC:ach", "PMID:12204365", "PMID:15521631", "PMID:1845219", "PMID:19288526", "PMID:21818313", "PMID:22425988" ]
null
[]
[]
[]
[]
[]
[ "GO:0000322", "GO:0000323" ]
[]
[]
[]
[ "GO:0000322", "GO:0000323" ]
[]
[]
[]
[]
[]
[]
hjd
2018-05-03T17:48:59Z
false
true
7
GO:0106124
106,124
reservosome lumen
cellular_component
The volume enclosed by the membranes of a reservosome.
[ "GOC:ach", "PMID:12204365", "PMID:15521631", "PMID:18452191", "PMID:19288526", "PMID:21818313", "PMID:22425988" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0106123" ]
[ "part_of" ]
[ "GO:0106123" ]
[ "GO:0106123", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
hjd
2018-05-03T17:54:46Z
false
true
1
GO:0106125
106,125
reservosome matrix
cellular_component
A matrix composed of planar membranes, vesicles and lipid inclusions within the reservosome.
[ "GOC:ach", "PMID:12204365", "PMID:15521631", "PMID:18452191", "PMID:19288526", "PMID:21818313", "PMID:22425988" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0106123" ]
[ "part_of" ]
[ "GO:0106123" ]
[ "GO:0106123", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
hjd
2018-05-03T18:00:03Z
false
true
8
GO:0106126
106,126
reservosome membrane
cellular_component
The lipid bilayer surrounding a reservosome.
[ "GOC:ach", "PMID:12204365", "PMID:15521631", "PMID:18452191", "PMID:19288526", "PMID:21818313", "PMID:22425988" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0106123" ]
[ "part_of" ]
[ "GO:0106123" ]
[ "GO:0106123", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
hjd
2018-05-03T18:01:26Z
false
true
1
GO:0106128
106,128
negative regulation of store-operated calcium entry
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium entry.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:23447642" ]
null
[]
[]
[]
[]
[]
[ "GO:0051926", "GO:2001256" ]
[ "negatively_regulates GO:0002115" ]
[ "negatively_regulates" ]
[ "GO:0002115" ]
[ "GO:0002115", "GO:0051926", "GO:2001256" ]
[ "GO:0065007", "negatively_regulates GO:0002115" ]
[]
[]
[]
[]
[]
hjd
2018-05-10T18:59:12Z
false
true
2
GO:0106130
106,130
purine phosphoribosyltransferase activity
molecular_function
Catalysis of the reaction: RMP + diphosphate = R + 5-phospho-alpha-D-ribose 1-diphosphate.
[ "PMID:5123876" ]
null
[]
[]
[]
[]
[ "Reactome:R-HSA-74215 \"HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP\"", "Reactome:R-HSA-9734274 \"Defective HPRT1 does not convert guanine or hypoxanthine to GMP or IMP\"", "Reactome:R-HSA-9748951 \"HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP\"" ]
[ "GO:0016763" ]
[]
[]
[]
[ "GO:0016763" ]
[]
[]
[]
[]
[]
[]
hjd
2018-06-14T17:38:53Z
false
true
3
GO:0106134
106,134
positive regulation of cardiac muscle cell contraction
biological_process
Any process that activates or increases the frequency, rate or extent of cardiac muscle cell contraction.
[ "PMID:19525381" ]
null
[]
[]
[]
[]
[]
[ "GO:0086004", "GO:1903116" ]
[ "positively_regulates GO:0086003" ]
[ "positively_regulates" ]
[ "GO:0086003" ]
[ "GO:0086003", "GO:0086004", "GO:1903116" ]
[ "GO:0065007", "positively_regulates GO:0086003" ]
[]
[]
[]
[]
[]
hjd
2018-07-26T16:05:16Z
false
true
6
GO:0106136
106,136
lectin-induced modified bacterial internalization
biological_process
The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by secretion of lectins which bind to the bacterial surface. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
[ "GOC:rjd", "PMID:30049880" ]
null
[ "LIMBI" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0051702" ]
[]
[]
[]
[ "GO:0051702" ]
[]
[]
[]
[]
[]
[]
hjd
2018-08-09T17:27:18Z
false
true
2
GO:0106137
106,137
IkappaB kinase complex binding
molecular_function
Binding to a IkappaB kinase complex.
[ "GOC:pga", "PMID:12492477" ]
null
[]
[]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[]
[]
[]
hjd
2018-08-15T14:05:10Z
false
true
3
GO:0106138
106,138
Sec61 translocon complex binding
molecular_function
Binding to a Sec61 translocon complex.
[ "GOC:pga", "PMID:9792704" ]
null
[]
[]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[]
[]
[]
hjd
2018-08-15T14:50:29Z
false
true
2
GO:0106139
106,139
symbiont cell surface
cellular_component
The cell surface of a secondary, endosymbiont organism with which the first organism is interacting. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
[ "GOC:rjd", "PMID:30049880" ]
null
[ "endosymbiont cell surface" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0044217" ]
[]
[]
[]
[ "GO:0044217" ]
[]
[]
[]
[]
[]
[]
hjd
2018-08-15T18:56:57Z
false
true
6
GO:0106140
106,140
P-TEFb complex binding
molecular_function
Binding to a P-TEFb complex.
[ "GOC:pga", "PMID:18391197" ]
null
[]
[]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[]
[]
[]
hjd
2018-08-17T18:17:50Z
false
true
8
GO:0106141
106,141
flavin prenyltransferase activity
molecular_function
Catalysis of the reaction: dimethylallyl phosphate + FMNH2 = phosphate + prenyl-FMNH2.
[ "PMID:26083743", "RHEA:37743" ]
null
[]
[]
[]
[]
[ "EC:2.5.1.129", "RHEA:37743" ]
[ "GO:0004659" ]
[]
[]
[]
[ "GO:0004659" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.5.1.129", "skos:exactMatch RHEA:37743", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20661\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
hjd
2018-08-17T18:50:00Z
false
true
3
GO:0106142
106,142
rRNA (adenine-N1-)-methyltransferase activity
molecular_function
Catalysis of the reaction: S-adenosyl-L-methionine + adenine(645) in 25S rRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine(645) in 25S rRNA.
[ "EC:2.1.1.287", "PMID:23180764" ]
The m(1)A modification at position 645 in the large rRNA is highly conserved in eukaryotes.
[ "25S rRNA (adenine(645)-N(1))-methyltransferase", "25S rRNA m(1)A(645) methyltransferase" ]
[ "RELATED", "RELATED" ]
[]
[]
[ "EC:2.1.1.287", "RHEA:43792" ]
[ "GO:0016433" ]
[]
[]
[]
[ "GO:0016433" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.1.1.287", "skos:exactMatch RHEA:43792", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
hjd
2018-08-22T20:13:21Z
false
true
5