ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000005884 | ITGA3 | Integrin subunit alpha 3 | [
"P26006"
] | 17 | 50055968-50090481 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008572",
"CAB018594"
] | [
"CD49c",
"GAP-B3",
"MSK18",
"VCA-2",
"VLA3a"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [
"Integrin",
"Receptor"
] | [
"Cancer-related genes",
"Disease variant",
"Epidermolysis bullosa"
] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 15 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 108 | 4 |
ENSG00000005889 | ZFX | Zinc finger protein X-linked | [
"P17010"
] | X | 24149173-24216255 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA001748",
"HPA003877",
"HPA071863"
] | [
"ZNF926"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Nucleoli"
] | [] | [] | Approved | Supported | null | null | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 25: Non-specific - Transcription | Cluster 36: Non-specific - mRNA processing | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 109 | 8 |
ENSG00000005893 | LAMP2 | Lysosomal associated membrane protein 2 | [
"P13473"
] | X | 120426148-120469365 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005272",
"HPA029100"
] | [
"CD107b"
] | [
"CD markers",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Autophagy"
] | [] | [
"Disease variant",
"Glycogen storage disease"
] | [
"Endoplasmic reticulum",
"Vesicles",
"Plasma membrane"
] | [] | [] | [] | Supported | Supported | null | 29 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 11: White matter - Signal transduction | Cluster 36: Non-specific - mRNA processing | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 110 | 1 |
ENSG00000005961 | ITGA2B | Integrin subunit alpha 2b | [
"P08514"
] | 17 | 44372180-44389649 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB018611",
"HPA031168",
"HPA031169",
"HPA031170",
"HPA031171"
] | [
"CD41",
"CD41B",
"GP2B",
"PPP1R93"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"CD markers",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [
"Integrin",
"Receptor"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Enhanced | null | 8 | null | null | Cluster 41: Basophils - Unknown function | Cluster 48: Non-specific - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 47: Platelets - Hemostasis | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in some | 59 | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in many | 4 | Immune cell enriched | Detected in some | 14 | 0 | 0 | 0 | [] | [] | [] | 111 | 1 |
ENSG00000005981 | ASB4 | Ankyrin repeat and SOCS box containing 4 | [
"Q9Y574"
] | 7 | 95478444-95540233 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA055240"
] | [
"ASB-4"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 7 | null | null | null | Cluster 13: Oligodendrocytes - Mixed function | Cluster 65: Non-specific - Unknown function | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 112 | 7 |
ENSG00000006007 | GDE1 | Glycerophosphodiester phosphodiesterase 1 | [
"Q9NZC3"
] | 16 | 19501693-19522123 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA077420"
] | [
"MIR16"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [
"Vesicles"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | Approved | null | null | 7 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 11: White matter - Signal transduction | Cluster 54: Non-specific - Transcription | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 4 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 113 | 7 |
ENSG00000006015 | REX1BD | Required for excision 1-B domain containing | [
"Q96EN9"
] | 19 | 18588685-18592337 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043414"
] | [
"C19orf60",
"FLJ20850",
"FLJ30108",
"FLJ34606",
"FLJ37391"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 14 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 14: Neurons - Synaptic function | Cluster 23: Non-specific - Transcription | Cluster 65: Non-specific - Cell growth & division | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 114 | 6 |
ENSG00000006016 | CRLF1 | Cytokine receptor like factor 1 | [
"O75462"
] | 19 | 18572220-18607741 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041493",
"HPA041793"
] | [
"CISS",
"CISS1",
"CLF",
"CLF-1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Receptor"
] | [
"Disease variant"
] | [] | [] | [
"Secreted in other tissues"
] | [
"Receptor"
] | null | Approved | null | 40 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 7 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 115 | 3 |
ENSG00000006025 | OSBPL7 | Oxysterol binding protein like 7 | [
"Q9BZF2"
] | 17 | 47807372-47821834 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036076",
"HPA053083",
"HPA073967"
] | [
"MGC71150",
"ORP7"
] | [
"Predicted intracellular proteins"
] | [
"Lipid transport",
"Transport"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Uncertain | null | 1 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 32: Cerebral cortex - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 68: Foveolar cells - Mucosal defense | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 116 | 6 |
ENSG00000006042 | TMEM98 | Transmembrane protein 98 | [
"Q9Y2Y6"
] | 17 | 32927910-32945106 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040473",
"HPA053385"
] | [
"DKFZP564K1964"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Supported | Uncertain | null | 7 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 64: Connective tissue cells - ECM organization | Cluster 99: Retinal pigment epithelial cells - Retinol metabolism | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Immune cell enriched | Detected in single | 12 | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 117 | 2 |
ENSG00000006047 | YBX2 | Y-box binding protein 2 | [
"Q9Y2T7"
] | 17 | 7288263-7294639 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB012332",
"HPA053904",
"HPA056744"
] | [
"Contrin",
"CSDA3",
"MSY2"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"DNA-binding",
"RNA-binding"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 11 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in many | 87 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Rectum Adenocarcinoma"
] | [
"Rectum Adenocarcinoma"
] | 118 | 3 |
ENSG00000006062 | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14 | [
"Q99558"
] | 17 | 45263119-45317029 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027269",
"HPA027270"
] | [
"FTDCR1B",
"HS",
"HSNIK",
"NIK"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Disease variant"
] | [
"Vesicles",
"Cytosol"
] | [
"Nucleoplasm",
"Nucleoli fibrillar center"
] | [] | [] | Supported | Approved | null | 72 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 38: Sub-cortical - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 82: Dendritic cells - Antigen presentation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 120 | 5 |
ENSG00000006071 | ABCC8 | ATP binding cassette subfamily C member 8 | [
"Q09428"
] | 11 | 17392498-17476894 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB011451",
"HPA042318"
] | [
"ABC36",
"HHF1",
"HI",
"HRINS",
"MRP8",
"PHHI",
"SUR",
"SUR1",
"TNDM2"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [
"Receptor"
] | [
"Diabetes mellitus",
"Disease variant",
"FDA approved drug targets"
] | [
"Nucleoli",
"Golgi apparatus"
] | [
"Cytosol",
"Principal piece"
] | [] | [] | Approved | Approved | null | null | No | null | null | Cluster 24: Neurons - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 70: Non-specific - Protein processing | Group enriched | Detected in many | 4 | Cancer enriched | Detected in single | 9 | Cancer enriched | Detected in some | 7 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 121 | 2 |
ENSG00000006118 | TMEM132A | Transmembrane protein 132A | [
"Q24JP5"
] | 11 | 60924460-60937159 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051979",
"HPA060492"
] | [
"FLJ20539",
"GBP",
"HSPA5BP1"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Enhanced | Supported | null | No | No | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 27: Breast cancer - Unknown function | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 123 | 9 |
ENSG00000006128 | TAC1 | Tachykinin precursor 1 | [
"P20366"
] | 7 | 97732084-97740472 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014429"
] | [
"NKNA",
"NPK",
"TAC2"
] | [
"Predicted secreted proteins"
] | [] | [
"Neuropeptide",
"Neurotransmitter"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Neuropeptide"
] | null | Enhanced | null | 3 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 69: Skin cancer - ECM organization | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in many | 5 | Cancer enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 125 | 3 |
ENSG00000006194 | ZNF263 | Zinc finger protein 263 | [
"O14978"
] | 16 | 3283283-3301401 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035085",
"HPA035086"
] | [
"FPM315",
"ZKSCAN12",
"ZSCAN44"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm",
"Mitotic spindle"
] | [] | [] | Supported | Approved | null | 26 | Yes | No | Cluster 45: Eosinophils - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 54: Non-specific - Transcription | Cluster 103: Non-specific - Basic cellular processes | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 126 | 3 |
ENSG00000006282 | SPATA20 | Spermatogenesis associated 20 | [
"Q8TB22"
] | 17 | 50543058-50555852 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA027144",
"HPA031442"
] | [
"FLJ21347",
"SSP411",
"Tisp78"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Differentiation",
"Spermatogenesis"
] | [
"Developmental protein"
] | [] | [
"Principal piece"
] | [] | [
"Secreted in male reproductive system"
] | [
"Developmental protein"
] | Approved | Enhanced | null | 1 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 38: Sub-cortical - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 8 | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 128 | 1 |
ENSG00000006283 | CACNA1G | Calcium voltage-gated channel subunit alpha1 G | [
"O43497"
] | 17 | 50560715-50627474 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA004714"
] | [
"Cav3.1",
"NBR13"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins",
"Voltage-gated ion channels"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calcium channel",
"Ion channel",
"Voltage-gated channel"
] | [
"Disease variant",
"FDA approved drug targets",
"Neurodegeneration",
"Spinocerebellar ataxia"
] | [
"Nucleoplasm",
"Acrosome",
"Equatorial segment",
"Perinuclear theca"
] | [
"Nuclear bodies",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 129 | 5 |
ENSG00000006327 | TNFRSF12A | TNF receptor superfamily member 12A | [
"Q9NP84"
] | 16 | 3018445-3022383 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA007853"
] | [
"CD266",
"FN14",
"TweakR"
] | [
"Cancer-related genes",
"CD markers",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Angiogenesis",
"Apoptosis",
"Cell adhesion",
"Differentiation"
] | [
"Developmental protein",
"Receptor"
] | [
"Cancer-related genes"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 7 | null | Yes | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 12: Non-specific - Vasculature | Cluster 15: Kidney cancer - Membrane components | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 8 | 4 | 0 | 4 | [
"Skin Cutaneous Melanoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 130 | 7 |
ENSG00000006377 | DLX6 | Distal-less homeobox 6 | [
"P56179"
] | 7 | 97005553-97011040 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA030608",
"HPA061460"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"Developmental protein",
"DNA-binding"
] | [] | [
"Nuclear bodies"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 10: Ciliated cells - Ion channel activity | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 5 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 131 | 3 |
ENSG00000006432 | MAP3K9 | Mitogen-activated protein kinase kinase kinase 9 | [
"P80192"
] | 14 | 70722526-70809534 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000942"
] | [
"MEKK9",
"MLK1",
"PRKE1"
] | [
"Disease related genes",
"Enzymes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Stress response",
"Transcription",
"Transcription regulation"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [
"Intracellular and membrane"
] | [
"Transcription"
] | Approved | Approved | null | 13 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Rectum Adenocarcinoma"
] | [
"Rectum Adenocarcinoma"
] | 132 | 6 |
ENSG00000006451 | RALA | RAS like proto-oncogene A | [
"P11233"
] | 7 | 39623565-39708120 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047037",
"HPA065232"
] | [
"RAL"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Cell cycle",
"Cell division",
"Exocytosis"
] | [
"Hydrolase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Plasma membrane"
] | [
"Focal adhesion sites"
] | [] | [] | Supported | Approved | null | 27 | null | null | Cluster 11: T-cells - Unknown function | Cluster 7: Non-specific - Ribosome | Cluster 67: Non-specific - Unknown function | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 133 | 8 |
ENSG00000006453 | BAIAP2L1 | BAR/IMD domain containing adaptor protein 2 like 1 | [
"Q9UHR4"
] | 7 | 98291650-98401090 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019484",
"HPA021257",
"HPA023874",
"HPA029503"
] | [
"IRTKS"
] | [
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Enhanced | Enhanced | null | 30 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 39: Non-specific - Transcription | Cluster 68: Foveolar cells - Mucosal defense | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 134 | 8 |
ENSG00000006459 | KDM7A | Lysine demethylase 7A | [
"Q6ZMT4"
] | 7 | 140084746-140176983 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA012114"
] | [
"JHDM1D",
"KIAA1718"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Dioxygenase",
"Oxidoreductase"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli"
] | [] | [] | Approved | Uncertain | null | 1 | Yes | No | Cluster 7: Non-specific - Innate immune response | Cluster 25: Non-specific - Transcription | Cluster 32: Non-specific - Cell proliferation | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 135 | 5 |
ENSG00000006468 | ETV1 | ETS variant transcription factor 1 | [
"P50549"
] | 7 | 13891229-13991425 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA068389",
"HPA077249"
] | [
"ER81"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | Supported | 12 | No | No | null | Cluster 15: Non-specific - Transcription | Cluster 60: Prostate cancer - Unknown function | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 136 | 2 |
ENSG00000006530 | AGK | Acylglycerol kinase | [
"Q53H12"
] | 7 | 141551278-141655244 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020959",
"HPA053471"
] | [
"FLJ10842",
"MULK"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Kinase",
"Transferase"
] | [
"Cardiomyopathy",
"Cataract",
"Disease variant",
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [
"Vesicles"
] | [] | [] | Supported | Supported | null | 29 | null | null | Cluster 15: NK-cells - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 39: Non-specific - Transcription | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Prostate Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Prostate Adenocarcinoma"
] | 137 | 8 |
ENSG00000006534 | ALDH3B1 | Aldehyde dehydrogenase 3 family member B1 | [
"P43353"
] | 11 | 68008578-68029282 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038525"
] | [
"ALDH7"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Oxidoreductase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 34 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 7: Liver cancer - Metabolism | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 138 | 7 |
ENSG00000006555 | TTC22 | Tetratricopeptide repeat domain 22 | [
"Q5TAA0"
] | 1 | 54779712-54801323 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA035072"
] | [
"FLJ20619"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 7: Liver cancer - Metabolism | Cluster 84: Apical squamous epithelium - Cornification | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in many | 5 | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 139 | 4 |
ENSG00000006576 | PHTF2 | Putative homeodomain transcription factor 2 | [
"Q8N3S3"
] | 7 | 77798773-77957503 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA012312"
] | [
"DKFZp434D166"
] | [
"Predicted membrane proteins",
"Transcription factors"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 53: Neurons - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 4 | 0 | 4 | [] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Thyroid Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Thyroid Carcinoma"
] | 140 | 5 |
ENSG00000006606 | CCL26 | C-C motif chemokine ligand 26 | [
"Q9Y258"
] | 7 | 75769533-75789896 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"eotaxin-3",
"IMAC",
"MIP-4a",
"MIP-4alpha",
"SCYA26",
"TSC-1"
] | [
"Human disease related genes",
"Predicted secreted proteins"
] | [
"Chemotaxis",
"Inflammatory response"
] | [
"Cytokine"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Chemokine"
] | null | null | null | 6 | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 110: Mural cells - ECM organization | Cluster 1: Choroid plexus - Transmembrane transport | Group enriched | Detected in many | 4 | Cancer enriched | Detected in many | 6 | Group enriched | Detected in many | 4 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 141 | 6 |
ENSG00000006607 | FARP2 | FERM, ARH/RhoGEF and pleckstrin domain protein 2 | [
"O94887"
] | 2 | 241356285-241494841 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031226",
"HPA055592"
] | [
"FIR",
"FRG",
"KIAA0793",
"PLEKHC3"
] | [
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 11 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 6: Non-specific - Immune response | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 82: Dendritic cells - Antigen presentation | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 142 | 2 |
ENSG00000006611 | USH1C | USH1 protein network component harmonin | [
"Q9Y6N9"
] | 11 | 17493895-17544416 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013690",
"HPA027398",
"HPA027492",
"HPA028033"
] | [
"AIE-75",
"DFNB18",
"harmonin",
"NY-CO-37",
"NY-CO-38",
"PDZ-73",
"PDZ73",
"PDZD7C"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Hearing"
] | [] | [
"Cancer-related genes",
"Deafness",
"Non-syndromic deafness",
"Retinitis pigmentosa",
"Usher syndrome"
] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 9 | No | null | null | Cluster 28: Oligodendrocytes - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 26: Kidney & Intestine - Metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 143 | 6 |
ENSG00000006634 | DBF4 | DBF4 zinc finger | [
"Q9UBU7"
] | 7 | 87876216-87909553 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042923"
] | [
"ASK",
"chif",
"DBF4A",
"ZDBF1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"DNA replication"
] | [] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [] | [] | [] | Supported | null | null | 15 | Yes | Yes | null | Cluster 48: Non-specific - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in single | 24 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in some | null | Group enriched | Detected in many | 4 | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 145 | 4 |
ENSG00000006638 | TBXA2R | Thromboxane A2 receptor | [
"P21731"
] | 19 | 3594507-3606875 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA077366"
] | [] | [
"Disease related genes",
"G-protein coupled receptors",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"Disease variant"
] | [
"Plasma membrane"
] | [
"Nuclear speckles"
] | [] | [] | Supported | null | null | 20 | null | null | Cluster 34: B-cells - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 47: Platelets - Hemostasis | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enriched | Detected in many | 4 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 146 | 4 |
ENSG00000006652 | IFRD1 | Interferon related developmental regulator 1 | [
"O00458"
] | 7 | 112422887-112481017 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024122",
"HPA072413"
] | [
"PC4",
"TIS7"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Differentiation"
] | [
"Developmental protein"
] | [] | [
"Plasma membrane"
] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 2 | No | No | Cluster 21: Neutrophils - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 7: Liver cancer - Metabolism | Cluster 102: Non-specific - Mixed function | Cluster 8: Pancreas - Proteolysis | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 4 | 3 | 0 | 3 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 147 | 6 |
ENSG00000006659 | LGALS14 | Galectin 14 | [
"Q8TCE9"
] | 19 | 39704481-39709444 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065180"
] | [
"CLC2",
"PPL13"
] | [
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 43 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func. | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enriched | Detected in single | 65 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in some | 12 | Cell type enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 148 | 8 |
ENSG00000006695 | COX10 | Cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 | [
"Q12887"
] | 17 | 14069490-14231736 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA032005",
"HPA032006"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Heme biosynthesis",
"Lipid metabolism"
] | [
"Transferase"
] | [
"Disease variant",
"Leigh syndrome",
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [
"Nucleoli",
"Cytosol"
] | [] | [] | Supported | Supported | null | 3 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 23: Choroid plexus - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 55: Myocytes - Oxidative muscle function | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 149 | 4 |
ENSG00000006712 | PAF1 | PAF1 homolog, Paf1/RNA polymerase II complex component | [
"Q8N7H5"
] | 19 | 39385629-39391154 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041875",
"HPA071954"
] | [
"F23149_1",
"FLJ11123",
"PD2"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Wnt signaling pathway"
] | [] | [
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [
"Nucleoli fibrillar center",
"Vesicles"
] | [] | [] | Supported | Approved | null | 79 | null | null | Cluster 32: Basophils - Transcription | Cluster 6: Non-specific - Immune response | Cluster 4: Non-specific - Transcription | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 151 | 5 |
ENSG00000006715 | VPS41 | VPS41 subunit of HOPS complex | [
"P49754"
] | 7 | 38722974-38932394 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA020080",
"HPA020299"
] | [
"HVSP41"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Autophagy",
"Protein transport",
"Transport"
] | [] | [
"Disease variant",
"Neurodegeneration",
"Spinocerebellar ataxia"
] | [] | [] | [] | [] | null | Approved | null | 22 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 67: Non-specific - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 152 | 1 |
ENSG00000006740 | ARHGAP44 | Rho GTPase activating protein 44 | [
"Q17R89"
] | 17 | 12789498-12991643 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038814"
] | [
"KIAA0672",
"RICH-2",
"RICH2"
] | [
"Predicted intracellular proteins"
] | [
"Exocytosis"
] | [
"GTPase activation"
] | [] | [] | [] | [] | [] | null | Approved | null | 15 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 46: Lymphoma - Humoral immune response | Cluster 109: Neurons - Neuronal signaling | Cluster 10: Brain - Synaptic signal transduction | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Colon Adenocarcinoma"
] | [] | [
"Colon Adenocarcinoma"
] | 153 | 9 |
ENSG00000006744 | ELAC2 | ElaC ribonuclease Z 2 | [
"Q9BQ52"
] | 17 | 12991612-13018065 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019535"
] | [
"FLJ10530",
"HPC2"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [
"Endonuclease",
"Hydrolase",
"Nuclease"
] | [
"Disease variant",
"Primary mitochondrial disease",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 26 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 27: Non-specific - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 154 | 7 |
ENSG00000006747 | SCIN | Scinderin | [
"Q9Y6U3"
] | 7 | 12570577-12660182 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020518",
"HPA024264"
] | [
"KIAA1905"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin capping",
"Actin-binding"
] | [] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 6 | No | No | null | Cluster 20: Macrophages & Microglia - Immune response | Cluster 15: Kidney cancer - Membrane components | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 26: Kidney & Intestine - Metabolism | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 4 | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [] | [
"Rectum Adenocarcinoma"
] | [
"Rectum Adenocarcinoma"
] | 155 | 3 |
ENSG00000006756 | ARSD | Arylsulfatase D | [
"P51689"
] | X | 2903972-2929349 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA004694",
"HPA063835"
] | [
"ASD"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Hydrolase"
] | [] | [
"Vesicles",
"Lipid droplets"
] | [] | [] | [] | Approved | Approved | null | null | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 8: Immune cells - Immune response | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 60: Stomach - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 156 | 7 |
ENSG00000006757 | PNPLA4 | Patatin like phospholipase domain containing 4 | [
"P41247"
] | X | 7898247-7927739 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003656"
] | [
"DXS1283E",
"GS2",
"iPLA2eta"
] | [
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Lipid degradation",
"Lipid metabolism"
] | [
"Hydrolase"
] | [
"Primary mitochondrial disease"
] | [] | [] | [] | [] | null | Approved | null | 5 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 46: Brainstem - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 97: Non-specific - Cellular respiration | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 157 | 2 |
ENSG00000006831 | ADIPOR2 | Adiponectin receptor 2 | [
"Q86V24"
] | 12 | 1688574-1788674 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043737"
] | [
"ACDCR2",
"PAQR2"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Receptor"
] | [] | [] | [] | [] | [] | null | Approved | null | 5 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 38: Non-specific - Transcription | Cluster 104: Brain endothelial cells - Blood brain barrier | Cluster 68: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 159 | 8 |
ENSG00000006837 | CDKL3 | Cyclin dependent kinase like 3 | [
"Q8IVW4"
] | 5 | 134286350-134371047 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA027751"
] | [
"NKIAMRE"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Uncertain | null | null | 23 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 105: Non-specific - Mixed function | Cluster 67: Testis - Mixed function | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 160 | 1 |
ENSG00000007001 | UPP2 | Uridine phosphorylase 2 | [
"O95045"
] | 2 | 157876702-158136154 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035225",
"HPA035226"
] | [
"UDRPASE2",
"UP2",
"UPASE2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles",
"Mitochondria"
] | [] | [] | Approved | null | null | 3 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 76: Non-specific - Metabolism | Group enriched | Detected in some | 15 | Not detected | Not detected | null | Group enriched | Detected in some | 4 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 161 | 8 |
ENSG00000007038 | PRSS21 | Serine protease 21 | [
"Q9Y6M0"
] | 16 | 2817180-2826304 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008477"
] | [
"ESP-1",
"TEST1"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [] | [
"Cytosol",
"Mid piece",
"Principal piece"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Approved | Enhanced | null | 1 | null | null | Cluster 46: Basophils - Proteolysis | null | Cluster 47: Leukemia - Hemostasis | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in many | 5 | 0 | 0 | 0 | [] | [] | [] | 162 | 5 |
ENSG00000007047 | MARK4 | Microtubule affinity regulating kinase 4 | [
"Q96L34"
] | 19 | 45079288-45305284 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039186"
] | [
"FLJ90097",
"KIAA1860",
"MARKL1",
"Nbla00650",
"PAR-1D"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Cilium biogenesis/degradation",
"Mitosis"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 23 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | 163 | 2 |
ENSG00000007062 | PROM1 | Prominin 1 | [
"O43490"
] | 4 | 15963076-16084378 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004922",
"CAB011525",
"HPA031053",
"CAB080375",
"CAB080376"
] | [
"AC133",
"CD133",
"CORD12",
"MCDR2",
"PROML1",
"RP41",
"STGD4"
] | [
"CD markers",
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Cone-rod dystrophy",
"Disease variant",
"Retinitis pigmentosa",
"Stargardt disease"
] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Enhanced | null | 7 | null | null | null | Cluster 47: Endothelial cells - Vasculature | Cluster 10: Ciliated cells - Ion channel activity | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 164 | 2 |
ENSG00000007080 | CCDC124 | Coiled-coil domain containing 124 | [
"Q96CT7"
] | 19 | 17933015-17943991 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041708",
"HPA046765"
] | [
"Lso2",
"oxs1"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division"
] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Enhanced | Supported | null | 35 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 23: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 165 | 9 |
ENSG00000007129 | CEACAM21 | CEA cell adhesion molecule 21 | [
"Q3KPI0"
] | 19 | 41549518-41586844 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA043411"
] | [
"FLJ13540",
"R29124_1"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 35: RS4;11 - Unknown function | Cluster 102: Non-specific - Mixed function | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in some | null | Group enriched | Detected in some | 8 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 166 | 8 |
ENSG00000007168 | PAFAH1B1 | Platelet activating factor acetylhydrolase 1b regulatory subunit 1 | [
"P43034"
] | 17 | 2593210-2685615 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004489",
"HPA020036"
] | [
"LIS1",
"MDCR",
"MDS",
"NudF",
"PAFAH"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Differentiation",
"Lipid degradation",
"Lipid metabolism",
"Mitosis",
"Neurogenesis",
"Transport"
] | [
"Developmental protein"
] | [
"Disease variant",
"Lissencephaly"
] | [
"Centrosome"
] | [
"Mid piece"
] | [] | [] | Supported | Approved | null | 85 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 1: Neurons - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 167 | 5 |
ENSG00000007171 | NOS2 | Nitric oxide synthase 2 | [
"P35228"
] | 17 | 27756766-27800529 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002014"
] | [
"HEP-NOS",
"iNOS",
"NOS",
"NOS2A"
] | [
"Cancer-related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Calmodulin-binding",
"Oxidoreductase"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | 11 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 77: Intestine - Digestion | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 4 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 168 | 3 |
ENSG00000007174 | DNAH9 | Dynein axonemal heavy chain 9 | [
"Q9NYC9"
] | 17 | 11598470-11969748 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020639",
"HPA052641"
] | [
"DNAH17L",
"Dnahc9",
"DNAL1",
"DYH9",
"HL-20",
"HL20",
"KIAA0357"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [
"Motor protein"
] | [
"Ciliopathy",
"Disease variant",
"Kartagener syndrome",
"Primary ciliary dyskinesia"
] | [
"Flagellar centriole",
"End piece"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 1 | null | null | null | Cluster 3: Choroid plexus - Cilium | Cluster 69: Skin cancer - ECM organization | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | 169 | 9 |
ENSG00000007202 | BLTP2 | Bridge-like lipid transfer protein family member 2 | [
"Q14667"
] | 17 | 28614446-28645454 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042781"
] | [
"BCOX",
"BCOX1",
"CT101",
"DKFZp686M0843",
"FMP27",
"Hob",
"KIAA0100",
"MGC111488"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nuclear speckles",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 4 | No | No | Cluster 13: Non-specific - Mitochondria | Cluster 49: Hindbrain - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 170 | 4 |
ENSG00000007237 | GAS7 | Growth arrest specific 7 | [
"O60861"
] | 17 | 9910606-10198606 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004838",
"HPA064678"
] | [
"KIAA0394",
"MGC1348"
] | [
"Cancer-related genes",
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein"
] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Plasma membrane"
] | [
"Actin filaments",
"Focal adhesion sites"
] | [] | [] | Approved | Enhanced | null | 7 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 53: Neurons - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in all | 4 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in all | 4 | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 172 | 2 |
ENSG00000007255 | TRAPPC6A | Trafficking protein particle complex subunit 6A | [
"O75865"
] | 19 | 45162928-45178237 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043043"
] | [
"HSPC289",
"MGC2650",
"TRS33"
] | [
"Predicted intracellular proteins"
] | [
"ER-Golgi transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 9 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 13: Oligodendrocytes - Mixed function | Cluster 41: Non-specific - Nucleosome assembly | Cluster 97: Non-specific - Cellular respiration | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 173 | 2 |
ENSG00000007264 | MATK | Megakaryocyte-associated tyrosine kinase | [
"P42679"
] | 19 | 3777970-3802129 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004847",
"HPA066547"
] | [
"CHK",
"CTK",
"DKFZp434N1212",
"HHYLTK",
"HYL",
"HYLTK",
"Lsk",
"MGC1708",
"MGC2101"
] | [
"Cancer-related genes",
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes"
] | [
"Microtubules"
] | [
"Cytokinetic bridge",
"Mitotic spindle",
"Centriolar satellite",
"Cytosol"
] | [] | [] | Approved | Approved | null | 11 | Yes | null | Cluster 15: NK-cells - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 5 | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Breast Invasive Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 174 | 8 |
ENSG00000007306 | CEACAM7 | CEA cell adhesion molecule 7 | [
"Q14002"
] | 19 | 41673303-41706976 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA069621",
"HPA073910"
] | [
"CEA",
"CGM2"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 1 | null | null | null | null | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 17: Intestine - Digestion | Tissue enriched | Detected in some | 9 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 10 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 175 | 1 |
ENSG00000007312 | CD79B | CD79b molecule | [
"P40259"
] | 17 | 63928738-63932336 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA009178",
"CAB009751",
"HPA044107"
] | [
"B29",
"Ig-beta",
"IGB",
"Igbeta"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted membrane proteins"
] | [
"Adaptive immunity",
"Immunity"
] | [
"Receptor"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 4 | null | null | Cluster 23: B-cells - Immunoglobulins | null | Cluster 46: Lymphoma - Humoral immune response | Cluster 102: Non-specific - Mixed function | Cluster 18: Lymphoid tissue - Immune response | Tissue enriched | Detected in many | 4 | Cancer enriched | Detected in some | 6 | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in some | 7 | Group enriched | Detected in all | 4 | 7 | 0 | 7 | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | 176 | 3 |
ENSG00000007314 | SCN4A | Sodium voltage-gated channel alpha subunit 4 | [
"P35499"
] | 17 | 63938554-63972918 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA070997"
] | [
"HYKPP",
"HYPP",
"Nav1.4",
"SkM1"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Sodium transport",
"Transport"
] | [
"Ion channel",
"Sodium channel",
"Voltage-gated channel"
] | [
"Congenital myasthenic syndrome",
"Disease variant",
"FDA approved drug targets"
] | [
"Golgi apparatus"
] | [] | [] | [] | Uncertain | null | null | null | null | null | null | null | Cluster 33: Sarcoma - Muscle contraction | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 19: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 177 | 1 |
ENSG00000007341 | ST7L | Suppression of tumorigenicity 7 like | [
"Q8TDW4"
] | 1 | 112523514-112620825 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA042324",
"HPA075418"
] | [
"FAM4B",
"FLJ20284",
"ST7R",
"STLR"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Centrosome"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 30: Non-specific - DNA binding | Cluster 31: Non-specific - Transcription | Cluster 37: Non-specific - mRNA processing | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Skin Cutaneous Melanoma"
] | [
"Skin Cutaneous Melanoma"
] | 178 | 6 |
ENSG00000007350 | TKTL1 | Transketolase like 1 | [
"P51854"
] | X | 154295795-154330350 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000505",
"HPA029155",
"CAB032191"
] | [
"TKR",
"TKT2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Developmental protein",
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 1 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 12: Non-specific - Vasculature | Cluster 51: Myeloma - Immunoglobulins | Cluster 106: Spermatogonia - Spermatogonial differentiation | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in some | 33 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in many | 6 | Group enriched | Detected in some | 11 | Group enriched | Detected in many | 5 | 0 | 0 | 0 | [] | [] | [] | 179 | 5 |
ENSG00000007372 | PAX6 | Paired box 6 | [
"P26367"
] | 11 | 31784779-31817961 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030775",
"CAB034143"
] | [
"AN",
"AN1",
"AN2",
"D11S812E",
"WAGR"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transcription factors"
] | [
"Differentiation",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding",
"Repressor"
] | [
"Disease variant",
"Peters anomaly"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | Supported | 98 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 5: Rhabdoid - Unknown function | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in some | 8 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 180 | 8 |
ENSG00000007376 | RPUSD1 | RNA pseudouridine synthase domain containing 1 | [
"Q9UJJ7"
] | 16 | 784974-788397 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041144",
"HPA041938"
] | [
"C16orf40",
"MGC19600",
"RLUCL"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm",
"Cell Junctions",
"Cytosol"
] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 32: Cerebral cortex - Mixed function | Cluster 54: Non-specific - Transcription | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 181 | 2 |
ENSG00000007384 | RHBDF1 | Rhomboid 5 homolog 1 | [
"Q96CC6"
] | 16 | 58059-76355 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA077399"
] | [
"C16orf8",
"Dist1",
"EGFR-RS",
"FLJ2235",
"iRhom1"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Protein transport",
"Transport"
] | [
"Growth factor binding"
] | [] | [
"Vesicles"
] | [] | [] | [] | Uncertain | null | null | null | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Rectum Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 182 | 1 |
ENSG00000007392 | LUC7L | LUC7 like | [
"Q9NQ29"
] | 16 | 188969-229463 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA056424",
"HPA069321"
] | [
"hLuc7B1",
"Luc7",
"LUC7B1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Mitochondria"
] | [] | [] | Approved | Supported | null | 34 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 35: RS4;11 - Unknown function | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 183 | 8 |
ENSG00000007402 | CACNA2D2 | Calcium voltage-gated channel auxiliary subunit alpha2delta 2 | [
"Q9NY47"
] | 3 | 50362613-50504244 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034771"
] | [
"alpha2delta-2",
"KIAA0558"
] | [
"Disease related genes",
"FDA approved drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calcium channel",
"Ion channel",
"Voltage-gated channel"
] | [
"Disease variant",
"Epilepsy",
"FDA approved drug targets"
] | [
"Cytosol"
] | [
"Plasma membrane",
"Flagellar centriole",
"Mid piece"
] | [] | [] | Approved | Enhanced | null | 1 | null | null | Cluster 11: T-cells - Unknown function | Cluster 1: Neurons - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 81: Alveolar cells - Lung function | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 184 | 9 |
ENSG00000007516 | BAIAP3 | BAI1 associated protein 3 | [
"O94812"
] | 16 | 1333638-1349441 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015627",
"HPA015979"
] | [
"BAP3",
"KIAA0734"
] | [
"Predicted intracellular proteins"
] | [
"Exocytosis",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | Supported | 3 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 70: DU4475 - Unknown function | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 20: Pituitary gland - Hormone signaling | Group enriched | Detected in many | 10 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 185 | 7 |
ENSG00000007520 | TSR3 | TSR3 ribosome maturation factor | [
"Q9UJK0"
] | 16 | 1349240-1351878 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040760",
"HPA046265"
] | [
"C16orf42",
"MGC24381"
] | [
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis",
"rRNA processing"
] | [
"Transferase"
] | [] | [
"Cytosol"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Uncertain | null | 5 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 19: Astrocytes - Mixed function | Cluster 54: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 186 | 7 |
ENSG00000007541 | PIGQ | Phosphatidylinositol glycan anchor biosynthesis class Q | [
"Q9BRB3"
] | 16 | 566995-584109 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039105",
"HPA039828",
"HPA061414"
] | [
"GPI1",
"hGPI1"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"GPI-anchor biosynthesis"
] | [] | [
"Disease variant",
"Epilepsy"
] | [
"Golgi apparatus",
"Vesicles"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 10 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 32: Cerebral cortex - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 187 | 2 |
ENSG00000007545 | CRAMP1 | Cramped chromatin regulator homolog 1 | [
"Q96RY5"
] | 16 | 1612337-1677908 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041752"
] | [
"CRAMP1L",
"KIAA1426"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 3 | No | No | null | Cluster 15: Non-specific - Transcription | Cluster 54: Non-specific - Transcription | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 188 | 5 |
ENSG00000007866 | TEAD3 | TEA domain transcription factor 3 | [
"Q99594"
] | 6 | 35473597-35497079 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA028906"
] | [
"ETFR-1",
"TEAD5",
"TEF-5"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 13 | null | null | null | Cluster 44: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 189 | 2 |
ENSG00000007908 | SELE | Selectin E | [
"P16581"
] | 1 | 169722640-169764705 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002143"
] | [
"CD62E",
"ELAM",
"ELAM1",
"ESEL"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"CD markers",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Enhanced | null | 3 | null | null | null | Cluster 12: Non-specific - Vasculature | Cluster 27: Breast cancer - Unknown function | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Not detected | Not detected | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in some | 26 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 190 | 8 |
ENSG00000007923 | DNAJC11 | DnaJ heat shock protein family (Hsp40) member C11 | [
"Q9NVH1"
] | 1 | 6634168-6701924 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023707",
"HPA028705"
] | [
"FLJ10737"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Chaperone"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Uncertain | null | 44 | No | No | Cluster 13: Non-specific - Mitochondria | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 37: Non-specific - mRNA processing | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 191 | 8 |
ENSG00000007933 | FMO3 | Flavin containing dimethylaniline monoxygenase 3 | [
"P31513"
] | 1 | 171090901-171117819 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA013750"
] | [
"FMOII"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Monooxygenase",
"Oxidoreductase"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 3 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 40 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in many | 8 | Cell type enriched | Detected in some | 12 | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 192 | 3 |
ENSG00000007944 | MYLIP | Myosin regulatory light chain interacting protein | [
"Q8WY64"
] | 6 | 16129086-16148248 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"IDOL",
"MIR"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [] | [] | [] | [] | null | null | null | 40 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 11: White matter - Signal transduction | Cluster 46: Lymphoma - Humoral immune response | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 5 | 2 | 4 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 193 | 1 |
ENSG00000007952 | NOX1 | NADPH oxidase 1 | [
"Q9Y5S8"
] | X | 100843324-100874359 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"GP91-2",
"MOX1",
"NOH-1",
"NOH-1L",
"NOH1"
] | [
"Disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Electron transport",
"Transport"
] | [
"Oxidoreductase"
] | [] | [] | [] | [] | [] | null | null | null | 2 | null | null | null | null | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 17: Intestine - Digestion | Tissue enriched | Detected in some | 24 | Cancer enriched | Detected in some | 7 | Group enriched | Detected in many | 19 | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 194 | 3 |
ENSG00000007968 | E2F2 | E2F transcription factor 2 | [
"Q14209"
] | 1 | 23506438-23531233 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB016313"
] | [
"E2F-2"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Cell cycle",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 14 | null | Yes | Cluster 42: Non-specific - Vesicular transport | null | Cluster 46: Lymphoma - Humoral immune response | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 44: Bone marrow - Nuclear processes | Group enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in some | 6 | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Head and Neck Squamous Cell Carcinoma",
"Stomach Adenocarcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 195 | 4 |
ENSG00000008018 | PSMB1 | Proteasome 20S subunit beta 1 | [
"P20618"
] | 6 | 170535120-170553307 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029635",
"HPA029637",
"CAB033911"
] | [
"HC5",
"PMSB1"
] | [
"Enzymes",
"Essential proteins",
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction"
] | [] | [
"Deafness",
"FDA approved drug targets",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 253 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 21: Non-specific - Metabolism | Cluster 28: Non-specific - Nuclear processes | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [] | [
"Bladder Urothelial Carcinoma",
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 196 | 7 |
ENSG00000008056 | SYN1 | Synapsin I | [
"P17600"
] | X | 47571901-47619857 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000397",
"CAB021929"
] | [
"MRX50"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [] | [] | [] | [] | null | Enhanced | null | 8 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in many | 8 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in all | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Stomach Adenocarcinoma"
] | [
"Stomach Adenocarcinoma"
] | 197 | 6 |
ENSG00000008083 | JARID2 | Jumonji and AT-rich interaction domain containing 2 | [
"Q92833"
] | 6 | 15246069-15522042 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA063889",
"CAB069890"
] | [
"JMJ"
] | [
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Developmental protein",
"Repressor"
] | [
"Intellectual disability"
] | [
"Nucleoplasm",
"Mitochondria"
] | [] | [] | [] | Supported | Approved | null | 14 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 15: Non-specific - Transcription | Cluster 34: Testis cancer - Unknown function | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 198 | 5 |
ENSG00000008086 | CDKL5 | Cyclin dependent kinase like 5 | [
"O76039"
] | X | 18425583-18653629 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002847",
"CAB011577"
] | [
"CFAP247",
"EIEE2",
"STK9"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 6 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 1: Neuronal - Visual perception | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 199 | 2 |
ENSG00000008118 | CAMK1G | Calcium/calmodulin dependent protein kinase IG | [
"Q96NX5"
] | 1 | 209583714-209613939 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA077157"
] | [
"CLICKIII",
"dJ272L16.1",
"VWS1"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Allosteric enzyme",
"Calmodulin-binding",
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Primary cilium",
"Basal body"
] | [] | [] | Approved | null | null | 4 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 65: Brain - Transcription | Tissue enhanced | Detected in some | null | Group enriched | Detected in some | 5 | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 200 | 5 |
ENSG00000008128 | CDK11A | Cyclin dependent kinase 11A | [
"Q9UQ88"
] | 1 | 1702379-1724357 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010467",
"HPA025061",
"HPA073626"
] | [
"CDC2L2",
"CDC2L3",
"CDK11-p110",
"CDK11-p46",
"CDK11-p58",
"p58GTA",
"PITSLRE"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Cell cycle"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nuclear speckles"
] | [
"Cytosol"
] | [] | [] | Supported | Supported | null | 22 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 47: Leukemia - Hemostasis | Cluster 102: Non-specific - Mixed function | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 201 | 2 |
ENSG00000008130 | NADK | NAD kinase | [
"O95544"
] | 1 | 1751232-1780457 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048909",
"HPA053368"
] | [
"FLJ13052"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 21 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 27: Non-specific - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Ovary Serous Cystadenocarcinoma"
] | 202 | 2 |
ENSG00000008196 | TFAP2B | Transcription factor AP-2 beta | [
"Q92481"
] | 6 | 50818723-50847619 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034683",
"HPA062942"
] | [
"AP-2beta",
"AP2-B"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Enhanced | null | 4 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in some | null | Group enriched | Detected in some | 10 | Cancer enriched | Detected in some | 11 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 203 | 9 |
ENSG00000008226 | DLEC1 | DLEC1 cilia and flagella associated protein | [
"Q9Y238"
] | 3 | 38039205-38124025 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019077"
] | [
"CFAP81",
"DLC1",
"FAP81"
] | [
"Disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis"
] | [] | [
"Tumor suppressor"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | null | null | null | null | Cluster 3: Choroid plexus - Cilium | Cluster 65: Non-specific - Unknown function | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Low cancer specificity | Detected in some | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 205 | 6 |
ENSG00000008256 | CYTH3 | Cytohesin 3 | [
"O43739"
] | 7 | 6161776-6272644 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA013979"
] | [
"ARNO3",
"cytohesin-3",
"GRP1",
"PSCD3"
] | [
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Uncertain | null | 10 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 53: Neurons - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enriched | Detected in all | 5 | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 206 | 9 |
ENSG00000008277 | ADAM22 | ADAM metallopeptidase domain 22 | [
"Q9P0K1"
] | 7 | 87934143-88202889 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA050325",
"CAB079064"
] | [
"MDC2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [
"Receptor"
] | [
"Disease variant",
"Epilepsy"
] | [
"Cell Junctions"
] | [] | [] | [] | Approved | null | Supported | 6 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in many | 5 | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 5 | 0 | 5 | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Thyroid Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Thyroid Carcinoma"
] | 207 | 2 |
ENSG00000008282 | SYPL1 | Synaptophysin like 1 | [
"Q16563"
] | 7 | 106090505-106112589 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA014141"
] | [
"SYPL"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 16 | null | null | Cluster 32: Basophils - Transcription | Cluster 30: White matter - Myelination | Cluster 46: Lymphoma - Humoral immune response | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 208 | 8 |
ENSG00000008283 | CYB561 | Cytochrome b561 | [
"P49447"
] | 17 | 63432304-63446354 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014753"
] | [
"CYB561A1",
"FRRS2"
] | [
"Disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Electron transport",
"Transport"
] | [
"Translocase"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 49 | null | null | Cluster 15: NK-cells - Unknown function | Cluster 1: Neurons - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 2 | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme"
] | 209 | 7 |
ENSG00000008294 | SPAG9 | Sperm associated antigen 9 | [
"O60271"
] | 17 | 50962174-51120868 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040446",
"HPA061458"
] | [
"CT89",
"FLJ13450",
"FLJ14006",
"FLJ26141",
"FLJ34602",
"HLC4",
"HSS",
"JIP-4",
"JIP4",
"JLP",
"KIAA0516",
"MGC117291",
"MGC14967",
"MGC74461",
"PHET",
"PIG6",
"SYD1"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Centriolar satellite",
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 22 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Group enriched | Detected in many | 6 | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 210 | 4 |
ENSG00000008300 | CELSR3 | Cadherin EGF LAG seven-pass G-type receptor 3 | [
"Q9NYQ7"
] | 3 | 48636463-48662886 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA062866"
] | [
"ADGRC3",
"CDHF11",
"EGFL1",
"FMI1",
"HFMI1",
"MEGF2"
] | [
"G-protein coupled receptors",
"Plasma proteins",
"Predicted membrane proteins"
] | [] | [
"Developmental protein",
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [] | [] | [] | [] | null | Approved | null | 2 | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 211 | 7 |
ENSG00000008311 | AASS | Aminoadipate-semialdehyde synthase | [
"Q9UDR5"
] | 7 | 122064583-122144308 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020637",
"HPA020728",
"HPA020734"
] | [
"LKRSDH",
"LORSDH"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Multifunctional enzyme",
"Oxidoreductase"
] | [] | [
"Mitochondria"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | Approved | Enhanced | null | 1 | Yes | No | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 72: Neuronal - Signal transduction | Cluster 103: Non-specific - Basic cellular processes | Cluster 31: Liver - Metabolism & Coagulation | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 212 | 7 |
ENSG00000008323 | PLEKHG6 | Pleckstrin homology and RhoGEF domain containing G6 | [
"Q3KR16"
] | 12 | 6310436-6328506 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041459",
"HPA058230"
] | [
"FLJ10665",
"MYOGEF"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Cell Junctions"
] | [
"Centrosome"
] | [] | [] | Supported | Uncertain | null | 1 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 19: Astrocytes - Mixed function | Cluster 34: Testis cancer - Unknown function | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 213 | 4 |
ENSG00000008324 | SS18L2 | SS18 like 2 | [
"Q9UHA2"
] | 3 | 42581840-42596934 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047377"
] | [
"KIAA-iso"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli",
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 22 | Yes | No | Cluster 39: T-cells - T-cell receptor | Cluster 28: Oligodendrocytes - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 214 | 5 |
ENSG00000008382 | MPND | MPN domain containing | [
"Q8N594"
] | 19 | 4343527-4360086 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043274",
"HPA045475"
] | [
"FLJ14981"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [
"Nucleoli rim"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 15 | No | No | Cluster 10: Non-specific - Membrane trafficking | Cluster 37: Neurons - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Stomach Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 215 | 1 |
ENSG00000008394 | MGST1 | Microsomal glutathione S-transferase 1 | [
"P10620"
] | 12 | 16347142-16609259 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044840"
] | [
"GST12",
"MGST-I",
"PMAN"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [
"Transferase"
] | [] | [
"Mitochondria"
] | [
"Endoplasmic reticulum"
] | [] | [] | Approved | Enhanced | null | 11 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 46: Brainstem - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 81: Alveolar cells - Lung function | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 216 | 1 |
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