ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000013293 | SLC7A14 | Solute carrier family 7 member 14 | [
"Q8TBB6"
] | 3 | 170459548-170586075 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045929"
] | [
"KIAA1613",
"PPP1R142"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Amino-acid transport",
"Transport"
] | [] | [
"Retinitis pigmentosa"
] | [
"Vesicles",
"Cytosol"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | Approved | Approved | null | 41 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 27: Cerebellum - Synaptic function | Group enriched | Detected in some | 4 | Cancer enriched | Detected in some | 6 | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 326 | 7 |
ENSG00000013297 | CLDN11 | Claudin 11 | [
"O75508"
] | 3 | 170418868-170454733 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009789",
"HPA013166",
"HPA013657"
] | [
"OSP",
"OTM"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [] | [
"Leukodystrophy"
] | [
"Lipid droplets",
"Cell Junctions"
] | [] | [] | [] | Approved | Enhanced | null | 9 | null | null | null | Cluster 30: White matter - Myelination | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 3: Oligodendrocytes - Myelination | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in some | 5 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 327 | 9 |
ENSG00000013364 | MVP | Major vault protein | [
"Q14764"
] | 16 | 29820394-29848039 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002321",
"CAB002752",
"CAB022717",
"HPA064740"
] | [
"LRP",
"VAULT1"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Transporters"
] | [
"mRNA transport",
"Protein transport",
"Translocation",
"Transport"
] | [
"Ribonucleoprotein"
] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 15 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 6: Non-specific - Immune response | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 329 | 6 |
ENSG00000013374 | NUB1 | Negative regulator of ubiquitin like proteins 1 | [
"Q9Y5A7"
] | 7 | 151341772-151378449 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021220",
"HPA050722",
"HPA053648"
] | [
"BS4",
"NUB1L",
"NYREN18"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | [] | Enhanced | Approved | null | 19 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 49: Hindbrain - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 82: Dendritic cells - Antigen presentation | Cluster 47: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 330 | 9 |
ENSG00000013375 | PGM3 | Phosphoglucomutase 3 | [
"O95394"
] | 6 | 83147324-83193936 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004998",
"HPA029759",
"HPA029760"
] | [
"AGM1",
"DKFZP434B187",
"PAGM"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism"
] | [
"Isomerase"
] | [
"Disease variant"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 14 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 28: Non-specific - Nuclear processes | Cluster 8: Non-specific - Secretory pathway | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 331 | 3 |
ENSG00000013392 | RWDD2A | RWD domain containing 2A | [
"Q9UIY3"
] | 6 | 83193357-83198935 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030105",
"HPA030106",
"HPA030107"
] | [
"dJ747H23.2",
"MGC13523",
"RWDD2"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | 4 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 60: Prostate cancer - Unknown function | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 332 | 2 |
ENSG00000013441 | CLK1 | CDC like kinase 1 | [
"P49759"
] | 2 | 200853009-200864691 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB033141",
"HPA062405"
] | [] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [] | [
"Nucleoplasm",
"Nuclear membrane"
] | [] | [] | [] | Supported | Approved | null | 20 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 75: Non-specific - Chaperones and protein folding | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 333 | 1 |
ENSG00000013503 | POLR3B | RNA polymerase III subunit B | [
"Q9NW08"
] | 12 | 106357748-106510198 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036466"
] | [
"C128",
"FLJ10388",
"RPC2"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"RNA polymerase related proteins"
] | [
"Antiviral defense",
"Immunity",
"Innate immunity",
"Transcription"
] | [
"Nucleotidyltransferase",
"Transferase"
] | [
"Charcot-Marie-Tooth disease",
"Disease variant",
"Leukodystrophy",
"Neurodegeneration",
"Neuropathy"
] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | Supported | null | 106 | null | null | Cluster 32: Basophils - Transcription | Cluster 31: Non-specific - Transcription | Cluster 38: Non-specific - Transcription | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 334 | 4 |
ENSG00000013523 | ANGEL1 | Angel homolog 1 | [
"Q9UNK9"
] | 14 | 76786009-76826246 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000948"
] | [
"Ccr4e",
"KIAA0759"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Approved | Uncertain | null | 8 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 20: Macrophages & Microglia - Immune response | Cluster 30: Non-specific - Gene expression regulation | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 335 | 9 |
ENSG00000013561 | RNF14 | Ring finger protein 14 | [
"Q9UBS8"
] | 5 | 141958328-141990292 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008716",
"HPA064746"
] | [
"ARA54",
"HFB30",
"TRIAD2"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 19 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 27: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 336 | 2 |
ENSG00000013563 | DNASE1L1 | Deoxyribonuclease 1 like 1 | [
"P49184"
] | X | 154401236-154412112 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA072635"
] | [
"DNAS1L1",
"DNASEX",
"DNL1L",
"XIB"
] | [
"Predicted intracellular proteins"
] | [] | [
"Endonuclease",
"Hydrolase",
"Nuclease"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Approved | null | 71 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 42: Choroid plexus - Mitochondria | Cluster 36: Non-specific - mRNA processing | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 337 | 4 |
ENSG00000013583 | HEBP1 | Heme binding protein 1 | [
"Q9NRV9"
] | 12 | 12974870-13000265 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA056417",
"HPA075277"
] | [
"HBP",
"HEBP"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | null | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 27: Non-specific - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 339 | 9 |
ENSG00000013588 | GPRC5A | G protein-coupled receptor class C group 5 member A | [
"Q8NFJ5"
] | 12 | 12891559-12917937 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007928",
"HPA046526"
] | [
"PEIG-1",
"RAI3",
"RAIG1",
"TIG1"
] | [
"G-protein coupled receptors",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"Tumor suppressor"
] | [
"Vesicles"
] | [
"Plasma membrane",
"Primary cilium",
"Primary cilium tip"
] | [] | [] | Supported | Enhanced | null | 6 | null | Yes | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 13: Lung - Secretion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 5 | 4 | 0 | 4 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 340 | 4 |
ENSG00000013619 | MAMLD1 | Mastermind like domain containing 1 | [
"Q13495"
] | X | 150361422-150514178 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003923"
] | [
"CG1",
"CXorf6",
"F18"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Golgi apparatus",
"Centrosome"
] | [] | [] | Supported | Uncertain | null | null | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 54: Non-specific - Transcription | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 341 | 3 |
ENSG00000013725 | CD6 | CD6 molecule | [
"P30203"
] | 11 | 60971680-61020377 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002489",
"CAB016252"
] | [
"Tp120"
] | [
"CD markers",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Adaptive immunity",
"Cell adhesion",
"Immunity",
"Innate immunity"
] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"Immunity"
] | null | Enhanced | null | 7 | null | null | Cluster 11: T-cells - Unknown function | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 59: Leukemia - T-cell receptor | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 10 | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in many | 7 | Group enriched | Detected in many | 33 | 5 | 0 | 5 | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | [] | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | 342 | 1 |
ENSG00000013810 | TACC3 | Transforming acidic coiled-coil containing protein 3 | [
"Q9Y6A5"
] | 4 | 1712858-1745171 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005781",
"HPA006050",
"CAB010111",
"HPA022039"
] | [
"ERIC-1",
"ERIC1",
"maskin",
"Tacc4"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [
"Centriolar satellite",
"Cytosol"
] | [
"Golgi apparatus",
"Mitotic spindle",
"Basal body"
] | [] | [] | Approved | Enhanced | null | 39 | Yes | Yes | Cluster 35: Neutrophils - Protein binding | Cluster 23: Choroid plexus - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 5 | 6 | 2 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 343 | 4 |
ENSG00000014123 | UFL1 | UFM1 specific ligase 1 | [
"O94874"
] | 6 | 96521595-96555276 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030558",
"HPA030559",
"HPA030560"
] | [
"KIAA0776",
"Maxer",
"NLBP",
"RCAD"
] | [
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Enhanced | null | 61 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 28: Non-specific - Nuclear processes | Cluster 8: Non-specific - Secretory pathway | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 344 | 2 |
ENSG00000014138 | POLA2 | DNA polymerase alpha 2, accessory subunit | [
"Q14181"
] | 11 | 65261913-65305959 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037570"
] | [
"FLJ21662"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"DNA replication"
] | [] | [] | [
"Nucleoplasm"
] | [
"Basal body",
"Cytosol"
] | [] | [] | Supported | Supported | null | 17 | null | Yes | Cluster 13: Non-specific - Mitochondria | Cluster 6: Non-specific - Immune response | Cluster 24: Non-specific - Unknown function | Cluster 102: Non-specific - Mixed function | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 345 | 4 |
ENSG00000014164 | ZC3H3 | Zinc finger CCCH-type containing 3 | [
"Q8IXZ2"
] | 8 | 143437659-143541447 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA023658",
"HPA050577"
] | [
"KIAA0150",
"ZC3HDC3"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA transport",
"Transport"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 124 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 48: Non-specific - Mixed function | Cluster 40: Non-specific - Unknown function | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 346 | 5 |
ENSG00000014216 | CAPN1 | Calpain 1 | [
"P07384"
] | 11 | 65180566-65212006 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005992"
] | [
"CANP",
"CANPL1",
"muCANP",
"muCL"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Disease variant",
"Hereditary spastic paraplegia",
"Neurodegeneration"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 36 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 49: Hindbrain - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 347 | 3 |
ENSG00000014257 | ACP3 | Acid phosphatase 3 | [
"P15309"
] | 3 | 132317369-132368302 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000071",
"HPA004335",
"HPA063916"
] | [
"ACP-3",
"ACPP",
"PAP",
"TM-PAP"
] | [
"Cancer-related genes",
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Lipid metabolism"
] | [
"Hydrolase"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Enhanced | null | 2 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 55: Non-specific - Transcription | Cluster 60: Prostate cancer - Unknown function | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 38: Non-specific - Basic cellular processes | Tissue enriched | Detected in many | 79 | Cancer enriched | Detected in many | 36 | Cancer enriched | Detected in many | 268 | Cell type enriched | Detected in many | 90 | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 348 | 7 |
ENSG00000014641 | MDH1 | Malate dehydrogenase 1 | [
"P40925"
] | 2 | 63588609-63607197 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027296",
"CAB047333",
"HPA054276"
] | [] | [
"Cancer-related genes",
"Citric acid cycle related proteins",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Tricarboxylic acid cycle"
] | [
"Oxidoreductase"
] | [
"Cancer-related genes",
"Disease variant",
"Epilepsy"
] | [
"Centrosome",
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 16 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 7: Liver cancer - Metabolism | Cluster 97: Non-specific - Cellular respiration | Cluster 41: Striated muscle - Muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Lung Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 349 | 8 |
ENSG00000014824 | SLC30A9 | Solute carrier family 30 member 9 | [
"Q6PML9"
] | 4 | 41990502-42090461 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004014"
] | [
"C4orf1",
"GAC63",
"HUEL",
"ZNT9"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Ion transport",
"Transcription",
"Transcription regulation",
"Transport",
"Zinc transport"
] | [] | [
"Disease variant"
] | [
"Mitochondria"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 25 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 14: Neurons - Synaptic function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 72: Kidney - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 350 | 5 |
ENSG00000014914 | MTMR11 | Myotubularin related protein 11 | [
"A4FU01"
] | 1 | 149928651-149936879 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA030351",
"HPA072906"
] | [
"CRA"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Centrosome"
] | [] | [] | [] | Approved | Enhanced | null | null | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 3: Choroid plexus - Cilium | Cluster 5: Rhabdoid - Unknown function | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 351 | 7 |
ENSG00000014919 | COX15 | Cytochrome c oxidase assembly homolog COX15 | [
"Q7KZN9"
] | 10 | 99710868-99732127 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037727",
"HPA037728",
"HPA066096"
] | [
"CEMCOX2"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Heme biosynthesis"
] | [
"Oxidoreductase"
] | [
"Disease variant",
"Leigh syndrome",
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Uncertain | null | 28 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 21: Non-specific - Metabolism | Cluster 52: Non-specific - Mitochondria | Cluster 105: Non-specific - Mixed function | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 352 | 2 |
ENSG00000015153 | YAF2 | YY1 associated factor 2 | [
"Q8IY57"
] | 12 | 42157104-42238349 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026867"
] | [] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 71 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 14: Neurons - Synaptic function | Cluster 38: Non-specific - Transcription | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 41: Striated muscle - Muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 354 | 8 |
ENSG00000015171 | ZMYND11 | Zinc finger MYND-type containing 11 | [
"Q15326"
] | 10 | 130088-254637 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015816"
] | [
"BRAM1",
"BS69"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"DNA-binding",
"Repressor"
] | [
"Intellectual disability",
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 26 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 13: Oligodendrocytes - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 7: Non-specific - Transcription | Cluster 33: Thyroid gland - Tissue development | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 355 | 8 |
ENSG00000015285 | WAS | WASP actin nucleation promoting factor | [
"P42768"
] | X | 48676596-48691431 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002022",
"CAB004290"
] | [
"IMD2",
"THC",
"WASP",
"WASPA"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes",
"Disease variant"
] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 52 | null | null | Cluster 19: Eosinophils - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 28 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Skin Cutaneous Melanoma"
] | [] | [
"Skin Cutaneous Melanoma"
] | 356 | 7 |
ENSG00000015413 | DPEP1 | Dipeptidase 1 | [
"P16444"
] | 16 | 89613308-89638456 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA009426",
"HPA012783"
] | [] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Dipeptidase",
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"FDA approved drug targets"
] | [
"Nucleoplasm",
"Cell Junctions"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Approved | Enhanced | null | 21 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 60: Stomach - Digestion | Group enriched | Detected in many | 8 | Cancer enriched | Detected in many | 5 | Group enriched | Detected in many | 5 | Group enriched | Detected in many | 8 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 357 | 2 |
ENSG00000015475 | BID | BH3 interacting domain death agonist | [
"P55957"
] | 22 | 17734138-17774770 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000722",
"CAB003771"
] | [] | [
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Cytosol"
] | [
"Mitochondria"
] | [] | [] | Supported | Enhanced | null | 32 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 24: Neurons - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 358 | 8 |
ENSG00000015479 | MATR3 | Matrin 3 | [
"P43243"
] | 5 | 139293674-139331677 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB033552",
"HPA036564",
"HPA036565"
] | [
"KIAA0723",
"MGC9105",
"MPD2",
"VCPDM"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Immunity",
"Innate immunity"
] | [
"RNA-binding"
] | [
"Amyotrophic lateral sclerosis",
"Disease variant",
"Neurodegeneration"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Supported | null | 134 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 31: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 47: Platelets - Hemostasis | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 359 | 2 |
ENSG00000015520 | NPC1L1 | NPC1 like intracellular cholesterol transporter 1 | [
"Q9UHC9"
] | 7 | 44512535-44541330 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB070127",
"CAB070128"
] | [
"SLC65A2"
] | [
"FDA approved drug targets",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Cholesterol metabolism",
"Lipid metabolism",
"Steroid metabolism",
"Sterol metabolism",
"Transport"
] | [] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 77: Intestine - Digestion | Group enriched | Detected in some | 9 | Group enriched | Detected in some | 6 | Group enriched | Detected in many | 6 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 360 | 4 |
ENSG00000015532 | XYLT2 | Xylosyltransferase 2 | [
"Q9H1B5"
] | 17 | 50346126-50363138 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"PXYLT2",
"XT-II"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [
"Disease variant"
] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | null | null | 12 | null | null | Cluster 11: T-cells - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 27: Breast cancer - Unknown function | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 60: Stomach - Digestion | Tissue enriched | Detected in all | 6 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 361 | 2 |
ENSG00000015592 | STMN4 | Stathmin 4 | [
"Q9H169"
] | 8 | 27235308-27258420 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA027765"
] | [
"RB3"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [
"Vesicles"
] | [] | [] | Uncertain | null | null | 1 | null | null | null | Cluster 30: White matter - Myelination | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in some | 21 | Cancer enriched | Detected in some | 5 | Cancer enriched | Detected in some | 27 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | 363 | 2 |
ENSG00000015676 | NUDCD3 | NudC domain containing 3 | [
"Q8IVD9"
] | 7 | 44379119-44490658 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019136",
"HPA019528",
"HPA019529"
] | [
"KIAA1068",
"NudCL"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Primary cilium",
"Primary cilium tip",
"Principal piece"
] | [] | [] | Approved | Enhanced | null | 59 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 33: Neurons - Mixed function | Cluster 67: Non-specific - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 364 | 3 |
ENSG00000016082 | ISL1 | ISL LIM homeobox 1 | [
"P61371"
] | 5 | 51383448-51394730 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048613",
"HPA057416"
] | [
"Isl-1",
"ISLET1"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear speckles",
"Mitochondria"
] | [] | [] | Approved | Approved | null | 16 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 42: Retina - Visual perception | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 7 | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 365 | 2 |
ENSG00000016391 | CHDH | Choline dehydrogenase | [
"Q8NE62"
] | 3 | 53812335-53846419 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036632",
"HPA036633",
"HPA058130"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [] | [
"Mitochondria"
] | [
"Nucleoli"
] | [] | [] | Approved | Enhanced | null | 4 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 19: Astrocytes - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 95: Tuft cells - Chemosensory signaling | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 14 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 366 | 8 |
ENSG00000016402 | IL20RA | Interleukin 20 receptor subunit alpha | [
"Q9UHF4"
] | 6 | 136999971-137045180 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB024990",
"HPA042281"
] | [
"IL-20R1",
"ZCYTOR7"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe"
] | 367 | 5 |
ENSG00000016490 | CLCA1 | Chloride channel accessory 1 | [
"A8K7I4"
] | 1 | 86468368-86500259 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052787",
"HPA059301"
] | [
"CaCC",
"CLCRG1"
] | [
"Predicted secreted proteins",
"Transporters"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [] | [] | [
"Secreted to digestive system"
] | [
"Transport"
] | null | Enhanced | null | null | null | null | null | null | Cluster 66: Non-specific - Mitochondria | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 77: Intestine - Digestion | Tissue enriched | Detected in some | 13 | Cancer enriched | Detected in some | 7 | Group enriched | Detected in some | 11 | Cell type enriched | Detected in some | 234 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 368 | 6 |
ENSG00000016864 | GLT8D1 | Glycosyltransferase 8 domain containing 1 | [
"Q68CQ7"
] | 3 | 52694486-52706032 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008808",
"HPA010588"
] | [
"AD-017",
"FLJ14611"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [] | [
"Golgi apparatus"
] | [
"Centrosome"
] | [] | [] | Approved | Approved | null | 28 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 23: Choroid plexus - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 370 | 7 |
ENSG00000017260 | ATP2C1 | ATPase secretory pathway Ca2+ transporting 1 | [
"P98194"
] | 3 | 130850595-131016712 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010207",
"HPA035116",
"HPA069684"
] | [
"ATP2C1A",
"BCPM",
"KIAA1347",
"PMR1",
"SPCA1"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Translocase"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | Supported | null | 4 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 371 | 5 |
ENSG00000017427 | IGF1 | Insulin like growth factor 1 | [
"P05019"
] | 12 | 102395874-102481744 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048946"
] | [
"IGF",
"IGF-I",
"IGF1A",
"IGFI"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [] | [
"Growth factor"
] | [
"Deafness",
"Dwarfism",
"Intellectual disability"
] | [] | [] | [
"Secreted to blood"
] | [
"Growth factor"
] | null | Approved | null | 7 | null | null | Cluster 17: B-cells - Immunoglobulins | Cluster 24: Neurons - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Group enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 372 | 7 |
ENSG00000017483 | SLC38A5 | Solute carrier family 38 member 5 | [
"Q8WUX1"
] | X | 48458537-48470260 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047411"
] | [
"JM24",
"SN2"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Vesicles",
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 9 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 47: Endothelial cells - Vasculature | Cluster 51: Myeloma - Immunoglobulins | Cluster 104: Brain endothelial cells - Blood brain barrier | Cluster 8: Pancreas - Proteolysis | Tissue enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [
"Glioblastoma Multiforme"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 373 | 9 |
ENSG00000017797 | RALBP1 | RalA binding protein 1 | [
"Q15311"
] | 18 | 9475009-9538114 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007622",
"CAB046010",
"HPA046651"
] | [
"RIP",
"RIP1",
"RLIP76"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins",
"Transporters"
] | [
"Transport"
] | [
"GTPase activation",
"Translocase"
] | [] | [
"Nucleoplasm",
"Plasma membrane"
] | [
"Nuclear bodies"
] | [] | [] | Supported | Approved | null | 104 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 55: Non-specific - Transcription | Cluster 13: Non-specific - Mixed function | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 58: Skin - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enriched | Detected in all | 10 | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 374 | 8 |
ENSG00000018189 | RUFY3 | RUN and FYVE domain containing 3 | [
"Q7L099"
] | 4 | 70704204-70808619 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022952",
"HPA022970"
] | [
"KIAA0871",
"RIPx",
"Singar1",
"ZFYVE30"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein"
] | [
"Oncogene"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 5 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 28: Oligodendrocytes - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 375 | 1 |
ENSG00000018236 | CNTN1 | Contactin 1 | [
"Q12860"
] | 12 | 40692439-41072415 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025200",
"HPA070467"
] | [
"F3",
"GP135"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell adhesion",
"Notch signaling pathway"
] | [] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Cell adhesion"
] | null | Enhanced | Approved | 6 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 14: Neurons - Synaptic function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 6 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 376 | 9 |
ENSG00000018280 | SLC11A1 | Solute carrier family 11 member 1 | [
"P49279"
] | 2 | 218382029-218396894 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA029590",
"HPA050378",
"HPA068540"
] | [
"LSH",
"NRAMP",
"NRAMP1"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Iron transport",
"Transport"
] | [] | [] | [
"Mitochondria"
] | [
"Nucleoli"
] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 12: Non-specific - Vasculature | Cluster 47: Leukemia - Hemostasis | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 5: Spleen - Immune response | Tissue enhanced | Detected in many | null | Not detected | Not detected | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 6 | Group enriched | Detected in some | 7 | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 377 | 1 |
ENSG00000018408 | WWTR1 | WW domain containing transcription regulator 1 | [
"Q9GZV5"
] | 3 | 149517235-149736714 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007415",
"CAB017483",
"CAB068248"
] | [
"DKFZp586I1419",
"TAZ"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 55 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 39: Astrocytes - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 378 | 5 |
ENSG00000018610 | STEEP1 | STING1 ER exit protein 1 | [
"Q9H5V9"
] | X | 119538149-119565409 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038245",
"HPA038617",
"HPA064831"
] | [
"CXorf56",
"FLJ22965"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Centrosome"
] | [] | [] | Supported | Uncertain | null | 7 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 36: Non-specific - mRNA processing | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 380 | 6 |
ENSG00000018625 | ATP1A2 | ATPase Na+/K+ transporting subunit alpha 2 | [
"P50993"
] | 1 | 160115759-160143591 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022230"
] | [
"FHM2",
"MHP2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Potassium transport",
"Sodium transport",
"Sodium/potassium transport",
"Transport"
] | [
"Translocase"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [] | [] | [] | [] | null | Enhanced | null | 11 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 22: Non-specific - Basic cellular functions | Cluster 25: Non-specific - Basic cellular processes | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in many | 20 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 381 | 9 |
ENSG00000018699 | TTC27 | Tetratricopeptide repeat domain 27 | [
"Q6P3X3"
] | 2 | 32628032-32821051 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031246"
] | [
"FLJ20272"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [
"Nucleoli"
] | [] | [] | Approved | Approved | null | 31 | No | No | Cluster 43: Non-specific - Transcription & Translation | Cluster 11: White matter - Signal transduction | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 7: Non-specific - Transcription | Cluster 57: Testis - Spermatogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 4 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 382 | 6 |
ENSG00000018869 | ZNF582 | Zinc finger protein 582 | [
"Q96NG8"
] | 19 | 56375846-56393538 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [
"HPA028858"
] | [
"FLJ30927"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 1 | No | No | Cluster 22: Eosinophils - Transcription | Cluster 55: Non-specific - Transcription | Cluster 4: Non-specific - Transcription | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 383 | 8 |
ENSG00000019102 | VSIG2 | V-set and immunoglobulin domain containing 2 | [
"Q96IQ7"
] | 11 | 124747474-124752255 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035919",
"HPA050147"
] | [
"CTH",
"CTXL"
] | [
"Predicted membrane proteins"
] | [
"Lipid metabolism"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Enhanced | null | 5 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 68: Foveolar cells - Mucosal defense | Cluster 17: Intestine - Digestion | Tissue enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 384 | 2 |
ENSG00000019169 | MARCO | Macrophage receptor with collagenous structure | [
"Q9UEW3"
] | 2 | 118942194-118994660 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA063793"
] | [
"SCARA2",
"SR-A6"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Immunity",
"Innate immunity"
] | [
"Receptor"
] | [] | [
"Golgi apparatus"
] | [
"Vesicles"
] | [] | [] | Approved | Enhanced | null | null | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 12: Non-specific - Vasculature | Cluster 50: Lymphoma - Unknown function | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in some | 15 | Group enriched | Detected in some | 4 | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 386 | 1 |
ENSG00000019186 | CYP24A1 | Cytochrome P450 family 24 subfamily A member 1 | [
"Q07973"
] | 20 | 54153446-54173986 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022261"
] | [
"CP24",
"CYP24",
"lncBCAS1-4_1",
"P450-CC24"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Monooxygenase",
"Oxidoreductase"
] | [
"Disease variant"
] | [
"Mitochondria"
] | [] | [] | [] | Approved | Enhanced | null | 35 | null | Yes | Cluster 11: T-cells - Unknown function | Cluster 1: Neurons - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 72: Kidney - Transmembrane transport | Group enriched | Detected in some | 5 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Breast Invasive Carcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 387 | 9 |
ENSG00000019485 | PRDM11 | PR/SET domain 11 | [
"Q9NQV5"
] | 11 | 45095806-45235110 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA057072"
] | [
"PFM8"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Methyltransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | 388 | 4 |
ENSG00000019505 | SYT13 | Synaptotagmin 13 | [
"Q7L8C5"
] | 11 | 45240302-45286341 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046224",
"HPA056602"
] | [
"KIAA1427"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | Uncertain | null | null | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 15: Kidney cancer - Membrane components | Cluster 96: Enteroendocrine cells - Neuropeptide signaling | Cluster 10: Brain - Synaptic signal transduction | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 389 | 3 |
ENSG00000019549 | SNAI2 | Snail family transcriptional repressor 2 | [
"O43623"
] | 8 | 48917598-48921740 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000971",
"CAB011671",
"HPA065884"
] | [
"SLUG",
"SLUGH",
"SLUGH1",
"SNAIL2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding",
"Repressor"
] | [
"Deafness",
"Waardenburg syndrome"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Supported | null | 17 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 44: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 390 | 8 |
ENSG00000019582 | CD74 | CD74 molecule | [
"P04233"
] | 5 | 150401637-150412969 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002506",
"HPA010592",
"CAB079994"
] | [
"CLIP",
"DHLAG"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Predicted secreted proteins",
"Transporters"
] | [
"Adaptive immunity",
"Immunity"
] | [
"Chaperone"
] | [
"Cancer-related genes"
] | [
"Golgi apparatus"
] | [] | [
"Secreted to blood"
] | [
"Immunity"
] | Supported | Enhanced | null | 19 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 21: Lymphoma - Adaptive immune response | Cluster 82: Dendritic cells - Antigen presentation | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in all | null | Group enriched | Detected in many | 7 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 5 | 1 | 0 | 1 | [
"Breast Invasive Carcinoma"
] | [] | [
"Breast Invasive Carcinoma"
] | 391 | 8 |
ENSG00000019991 | HGF | Hepatocyte growth factor | [
"P14210"
] | 7 | 81699010-81770438 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010333",
"HPA040360",
"HPA044088"
] | [
"DFNB39",
"F-TCF",
"HGFB",
"HPTA",
"SF"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [] | [
"Growth factor",
"Serine protease homolog"
] | [
"Cancer-related genes",
"Deafness",
"Non-syndromic deafness"
] | [] | [] | [
"Secreted to blood"
] | [
"Growth factor"
] | null | Approved | null | 5 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 24: Neurons - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 108: Fibroblasts - ECM organization | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enriched | Detected in many | 10 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 5 | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 392 | 7 |
ENSG00000019995 | ZRANB1 | Zinc finger RANBP2-type containing 1 | [
"Q9UGI0"
] | 10 | 124942123-124988189 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029239",
"HPA029240",
"HPA029241"
] | [
"TRABID"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway",
"Wnt signaling pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 345 | null | null | Cluster 24: Non-specific - Transcription | Cluster 16: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 393 | 4 |
ENSG00000020129 | NCDN | Neurochondrin | [
"Q9UBB6"
] | 1 | 35557473-35567274 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023676"
] | [
"NCDN-1",
"NCDN-2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | Supported | 28 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 33: Neurons - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in all | 25 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 394 | 6 |
ENSG00000020181 | ADGRA2 | Adhesion G protein-coupled receptor A2 | [
"Q96PE1"
] | 8 | 37784191-37844896 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008984",
"HPA012393"
] | [
"DKFZp434C211",
"DKFZp434J0911",
"FLJ14390",
"GPR124",
"KIAA1531",
"TEM5"
] | [
"G-protein coupled receptors",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Angiogenesis",
"Wnt signaling pathway"
] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [
"Plasma membrane"
] | [
"Vesicles"
] | [] | [] | Supported | Uncertain | null | 4 | null | null | null | Cluster 32: Cerebral cortex - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 110: Mural cells - ECM organization | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 395 | 1 |
ENSG00000020426 | MNAT1 | MNAT1 component of CDK activating kinase | [
"P51948"
] | 14 | 60734742-60969965 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000701",
"HPA001154",
"CAB004495"
] | [
"MAT1",
"RNF66"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 47 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 34: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 397 | 5 |
ENSG00000020577 | SAMD4A | Sterile alpha motif domain containing 4A | [
"Q9UPU9"
] | 14 | 54566117-54793315 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043061",
"HPA065309"
] | [
"DKFZP434H0350",
"hSmaug1",
"KIAA1053",
"SAMD4",
"Smaug",
"SMG",
"SMGA"
] | [
"Predicted intracellular proteins"
] | [
"Translation regulation"
] | [
"Repressor"
] | [] | [
"Cell Junctions"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 13 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 3: Rhabdoid - Membrane components | Cluster 103: Non-specific - Basic cellular processes | Cluster 67: Testis - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 398 | 9 |
ENSG00000020633 | RUNX3 | RUNX family transcription factor 3 | [
"Q13761"
] | 1 | 24899511-24965121 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004195",
"CAB025416",
"HPA059006"
] | [
"AML2",
"CBFA3",
"PEBP2A3"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 24 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 20: Macrophages & Microglia - Immune response | Cluster 55: Lymphoma - Immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma"
] | 399 | 2 |
ENSG00000020922 | MRE11 | MRE11 homolog, double strand break repair nuclease | [
"P49959"
] | 11 | 94415570-94493885 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002691",
"CAB004081"
] | [
"ATLD",
"MRE11A"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Host-virus interaction",
"Meiosis"
] | [
"Endonuclease",
"Exonuclease",
"Hydrolase",
"Nuclease"
] | [
"Cancer-related genes",
"Ciliopathy",
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 83 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 46: Brainstem - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 400 | 2 |
ENSG00000021300 | PLEKHB1 | Pleckstrin homology domain containing B1 | [
"Q9UF11"
] | 11 | 73646178-73662819 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"KPL1",
"PHR1",
"PHRET1"
] | [
"Predicted intracellular proteins"
] | [] | [
"Developmental protein"
] | [] | [] | [] | [] | [] | null | null | null | 5 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 19: Astrocytes - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | 401 | 1 |
ENSG00000021355 | SERPINB1 | Serpin family B member 1 | [
"P30740"
] | 6 | 2832332-2841959 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018871",
"HPA018882",
"HPA052642"
] | [
"EI",
"ELANH2",
"LEI",
"MNEI",
"PI2"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Protease inhibitor",
"Serine protease inhibitor"
] | [] | [
"Cytoplasmic bodies"
] | [] | [
"Secreted to blood"
] | [
"Enzyme inhibitor"
] | Supported | Enhanced | null | 2 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 402 | 6 |
ENSG00000021488 | SLC7A9 | Solute carrier family 7 member 9 | [
"P82251"
] | 19 | 32830509-32869767 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042591"
] | [
"CSNU3"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Amino-acid transport",
"Transport"
] | [] | [
"Cystinuria",
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 1 | null | null | null | null | Cluster 10: Ciliated cells - Ion channel activity | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 26: Kidney & Intestine - Metabolism | Group enriched | Detected in some | 6 | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 8 | Cell type enriched | Detected in many | 9 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 404 | 6 |
ENSG00000021574 | SPAST | Spastin | [
"Q9UBP0"
] | 2 | 32063556-32157637 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017311"
] | [
"ADPSP",
"FSP2",
"KIAA1083",
"SPG4"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Cell cycle",
"Cell division",
"Differentiation",
"Neurogenesis"
] | [
"Allosteric enzyme",
"Developmental protein",
"Isomerase"
] | [
"Disease variant",
"Hereditary spastic paraplegia",
"Neurodegeneration"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 17 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 405 | 9 |
ENSG00000021645 | NRXN3 | Neurexin 3 | [
"Q9HDB5",
"Q9Y4C0"
] | 14 | 78170373-79868291 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002727"
] | [
"C14orf60",
"KIAA0743"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Angiogenesis",
"Cell adhesion"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 2: Neurons - Nucleosome | Cluster 64: Connective tissue cells - ECM organization | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in many | 6 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 406 | 6 |
ENSG00000021762 | OSBPL5 | Oxysterol binding protein like 5 | [
"Q9H0X9"
] | 11 | 3087107-3166739 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038335",
"HPA038712",
"HPA058727"
] | [
"KIAA1534",
"OBPH1",
"ORP5"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Lipid transport",
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Enhanced | Approved | null | 7 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 49: Hindbrain - Mixed function | Cluster 70: DU4475 - Unknown function | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 407 | 4 |
ENSG00000021776 | AQR | Aquarius intron-binding spliceosomal factor | [
"O60306"
] | 15 | 34851782-34969742 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040624",
"HPA055647"
] | [
"fSAP164",
"IBP160",
"KIAA0560"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Helicase",
"Hydrolase",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | null | null | 85 | No | No | Cluster 22: Eosinophils - Transcription | Cluster 31: Non-specific - Transcription | Cluster 58: Non-specific - Nuclear processes | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 408 | 9 |
ENSG00000021826 | CPS1 | Carbamoyl-phosphate synthase 1 | [
"P31327"
] | 2 | 210477682-210679107 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB003781",
"HPA021400"
] | [
"GATD6"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Urea cycle"
] | [
"Allosteric enzyme",
"Ligase"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Nucleoli",
"Nucleoli rim"
] | [
"Mid piece",
"Principal piece"
] | [] | [] | Supported | Enhanced | null | 4 | null | null | null | Cluster 30: White matter - Myelination | Cluster 7: Liver cancer - Metabolism | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 16 | Cell type enriched | Detected in many | 20 | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 409 | 7 |
ENSG00000021852 | C8B | Complement C8 beta chain | [
"P07358"
] | 1 | 56929207-56974383 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023694"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Complement alternate pathway",
"Complement pathway",
"Cytolysis",
"Immunity",
"Innate immunity"
] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"Complement pathway"
] | null | Supported | null | 1 | null | null | null | null | Cluster 18: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 126 | Cancer enriched | Detected in single | 11 | Cancer enriched | Detected in some | 93 | Cell type enriched | Detected in some | 17 | Immune cell enriched | Detected in single | 23 | 1 | 2 | 0 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 410 | 1 |
ENSG00000022267 | FHL1 | Four and a half LIM domains 1 | [
"Q13642"
] | X | 136146702-136211359 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001040",
"HPA001391",
"CAB020817"
] | [
"bA535K18.1",
"FHL1B",
"FLH1A",
"KYO-T",
"MGC111107",
"SLIM1",
"XMPMA"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Differentiation"
] | [
"Developmental protein"
] | [
"Disease variant",
"Emery-Dreifuss muscular dystrophy"
] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Uncertain | Enhanced | null | 34 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 14: Neurons - Synaptic function | Cluster 64: Connective tissue cells - ECM organization | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 30: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in all | 7 | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 411 | 5 |
ENSG00000022277 | RTF2 | Replication termination factor 2 | [
"Q9BY42"
] | 20 | 56468585-56519449 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053986"
] | [
"C20orf43",
"CDAO5",
"HSPC164",
"RTFDC1"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | [] | Supported | Approved | null | 14 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 412 | 7 |
ENSG00000022355 | GABRA1 | Gamma-aminobutyric acid type A receptor subunit alpha1 | [
"P14867"
] | 5 | 161847063-161899981 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022502",
"HPA029363",
"HPA055746"
] | [
"EJM5"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Chloride channel",
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"Disease variant",
"Epilepsy",
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | Supported | 14 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 70: DU4475 - Unknown function | Cluster 109: Neurons - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Group enriched | Detected in some | 30 | Cancer enriched | Detected in single | 7 | Cancer enhanced | Detected in single | null | Group enriched | Detected in some | 7 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 413 | 1 |
ENSG00000022556 | NLRP2 | NLR family pyrin domain containing 2 | [
"Q9NX02"
] | 19 | 54953130-55001142 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021183"
] | [
"CLR19.9",
"FLJ20510",
"NALP2",
"NBS1",
"PAN1",
"PYPAF2"
] | [
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Immunity",
"Inflammatory response",
"Innate immunity"
] | [] | [
"Disease variant"
] | [
"Golgi apparatus",
"Vesicles",
"Cytosol"
] | [] | [] | [] | Supported | null | null | 5 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 15: Kidney cancer - Membrane components | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 414 | 1 |
ENSG00000022567 | SLC45A4 | Solute carrier family 45 member 4 | [
"Q5BKX6"
] | 8 | 141207166-141308305 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023154"
] | [
"KIAA1126"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Symport",
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 40: Non-specific - Unknown function | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 7 | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 415 | 9 |
ENSG00000022840 | RNF10 | Ring finger protein 10 | [
"Q8N5U6"
] | 12 | 120533480-120577588 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052643"
] | [
"KIAA0262",
"RIE2"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway"
] | [
"DNA-binding",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Mitochondria"
] | [] | [] | Approved | Approved | null | 39 | No | No | Cluster 42: Non-specific - Vesicular transport | Cluster 7: Non-specific - Ribosome | Cluster 38: Non-specific - Transcription | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 416 | 2 |
ENSG00000022976 | ZNF839 | Zinc finger protein 839 | [
"A8K0R7"
] | 14 | 102317377-102342702 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA020434"
] | [
"C14orf131"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 30: Non-specific - DNA binding | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 30: Non-specific - Gene expression regulation | Cluster 7: Non-specific - Transcription | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 417 | 6 |
ENSG00000023041 | ZDHHC6 | Zinc finger DHHC-type palmitoyltransferase 6 | [
"Q9H6R6"
] | 10 | 112424428-112447572 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014357"
] | [
"FLJ21952",
"ZNF376"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [
"Acyltransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Approved | null | 2 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 50: Non-specific - Nucleic acid binding | Cluster 52: Non-specific - Mitochondria | Cluster 57: Podocytes - Glomerular filtration | Cluster 72: Kidney - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 418 | 7 |
ENSG00000023171 | GRAMD1B | GRAM domain containing 1B | [
"Q3KR37"
] | 11 | 123358428-123627774 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008557",
"HPA075204"
] | [
"KIAA1201",
"LINC01059"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Lipid transport",
"Transport"
] | [] | [] | [
"Endoplasmic reticulum",
"Plasma membrane"
] | [
"Vesicles"
] | [] | [] | Supported | Approved | null | 7 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 5: Non-specific - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 4 | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 419 | 4 |
ENSG00000023191 | RNH1 | Ribonuclease/angiogenin inhibitor 1 | [
"P13489"
] | 11 | 494512-507300 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039223",
"HPA040781"
] | [
"RAI",
"RNH"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant"
] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | Enhanced | null | 33 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 30: White matter - Myelination | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 420 | 3 |
ENSG00000023228 | NDUFS1 | NADH:ubiquinone oxidoreductase core subunit S1 | [
"P28331"
] | 2 | 206114817-206159509 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064605",
"CAB070844"
] | [
"CI-75k"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Electron transport",
"Respiratory chain",
"Transport"
] | [
"Oxidoreductase",
"Translocase"
] | [
"Disease variant",
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 71 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 23: Choroid plexus - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 102: Non-specific - Mixed function | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 421 | 3 |
ENSG00000023318 | ERP44 | Endoplasmic reticulum protein 44 | [
"Q9BS26"
] | 9 | 99979185-100099052 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001318"
] | [
"KIAA0573",
"PDIA10",
"TXNDC4"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Stress response"
] | [
"Chaperone"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Other"
] | null | Supported | null | 28 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 2: Neurons - Nucleosome | Cluster 63: Non-specific - Protein processing | Cluster 8: Non-specific - Secretory pathway | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 423 | 8 |
ENSG00000023330 | ALAS1 | 5'-aminolevulinate synthase 1 | [
"P13196"
] | 3 | 52198086-52214327 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017498",
"HPA035860"
] | [
"ALAS",
"ALAS-H",
"ALAS3"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Heme biosynthesis"
] | [
"Acyltransferase",
"Transferase"
] | [] | [
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 44 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 12: Non-specific - Vasculature | Cluster 71: Lymphoma - Inflammatory response | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 424 | 4 |
ENSG00000023445 | BIRC3 | Baculoviral IAP repeat containing 3 | [
"Q13489"
] | 11 | 102317450-102339403 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002317"
] | [
"API2",
"c-IAP2",
"cIAP2",
"hiap-1",
"MALT2",
"MIHC",
"RNF49"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | Approved | 83 | null | null | Cluster 16: Non-specific - Cell proliferation | Cluster 23: Choroid plexus - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 82: Dendritic cells - Antigen presentation | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 3 | 0 | 3 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | 425 | 2 |
ENSG00000023516 | AKAP11 | A-kinase anchoring protein 11 | [
"Q9UKA4"
] | 13 | 42272152-42323261 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039089"
] | [
"AKAP220",
"DKFZp781I12161",
"FLJ11304",
"KIAA0629",
"PPP1R44",
"PRKA11"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli",
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 35 | null | null | Cluster 32: Basophils - Transcription | Cluster 14: Neurons - Synaptic function | Cluster 19: Non-specific - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 46: Brain & retina - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 426 | 6 |
ENSG00000023572 | GLRX2 | Glutaredoxin 2 | [
"Q9NS18"
] | 1 | 193090866-193106114 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023087",
"HPA057224"
] | [
"bA101E13.1",
"GRX2"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Electron transport",
"Transport"
] | [] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Supported | Supported | null | 2 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 45: Non-specific - Nuclear processes | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 14 | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 427 | 4 |
ENSG00000023608 | SNAPC1 | Small nuclear RNA activating complex polypeptide 1 | [
"Q16533"
] | 14 | 61762420-61796428 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA067076",
"HPA072276"
] | [
"PTFgamma",
"SNAP43"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | null | null | 23 | null | null | Cluster 24: Non-specific - Transcription | Cluster 25: Non-specific - Transcription | Cluster 72: Neuronal - Signal transduction | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 428 | 4 |
ENSG00000023697 | DERA | Deoxyribose-phosphate aldolase | [
"Q9Y315"
] | 12 | 15911302-16037381 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055897"
] | [
"CGI-26",
"DEOC"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Lyase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 6 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 8: Immune cells - Immune response | Cluster 38: Non-specific - Transcription | Cluster 47: Platelets - Hemostasis | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 429 | 4 |
ENSG00000023734 | STRAP | Serine/threonine kinase receptor associated protein | [
"Q9Y3F4"
] | 12 | 15882387-15903478 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027320",
"HPA055557",
"HPA073876"
] | [
"MAWD",
"pt-wd",
"UNRIP"
] | [
"Cancer-related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [
"Cell Junctions"
] | [] | [] | Supported | Approved | null | 73 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 14: Neurons - Synaptic function | Cluster 38: Non-specific - Transcription | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 6 | 2 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 430 | 7 |
ENSG00000023839 | ABCC2 | ATP binding cassette subfamily C member 2 | [
"Q92887"
] | 10 | 99782640-99852594 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA071145"
] | [
"CMOAT",
"cMRP",
"DJS",
"MRP2"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Lipid transport",
"Transport"
] | [
"Translocase"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | 15 | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 7: Liver cancer - Metabolism | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | 431 | 3 |
ENSG00000023892 | DEF6 | DEF6 guanine nucleotide exchange factor | [
"Q9H4E7"
] | 6 | 35297818-35321771 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038975",
"HPA038976"
] | [
"IBP",
"SLAT",
"SWAP70L"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 20 | Yes | null | Cluster 33: Non-specific - ATP binding | Cluster 20: Macrophages & Microglia - Immune response | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Breast Invasive Carcinoma"
] | [] | [
"Breast Invasive Carcinoma"
] | 432 | 3 |
ENSG00000023902 | PLEKHO1 | Pleckstrin homology domain containing O1 | [
"Q53GL0"
] | 1 | 150149183-150164720 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA061018"
] | [
"CKIP-1",
"OC120"
] | [
"Predicted intracellular proteins"
] | [] | [] | [
"Tumor suppressor"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | null | null | 34 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 35: RS4;11 - Unknown function | Cluster 47: Platelets - Hemostasis | Cluster 74: Non-specific - Signal transduction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 433 | 3 |
ENSG00000023909 | GCLM | Glutamate-cysteine ligase modifier subunit | [
"P48507"
] | 1 | 93885199-93909456 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009568",
"HPA023696",
"CAB040554"
] | [
"GLCLR"
] | [
"Cancer-related genes",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Glutathione biosynthesis"
] | [] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Uncertain | null | 8 | null | null | Cluster 1: T-cells - Unknown function | Cluster 49: Hindbrain - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Cancer enriched | Detected in all | 9 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 5 | 0 | 5 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 434 | 7 |
ENSG00000024048 | UBR2 | Ubiquitin protein ligase E3 component n-recognin 2 | [
"Q8IWV8"
] | 6 | 42564029-42693505 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA027869",
"HPA027880"
] | [
"bA49A4.1",
"C6orf133",
"dJ392M17.3",
"KIAA0349"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Plasma membrane"
] | [] | [] | Approved | Approved | null | 10 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 31: Non-specific - Transcription | Cluster 28: Non-specific - Nuclear processes | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 435 | 1 |
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