ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000008405 | CRY1 | Cryptochrome circadian regulator 1 | [
"Q16526"
] | 12 | 106991364-107093549 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB018762"
] | [
"PHLL1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"Sensory transduction",
"Transcription",
"Transcription regulation"
] | [
"Photoreceptor protein",
"Receptor",
"Repressor"
] | [] | [
"Nucleoplasm",
"Nuclear membrane",
"Microtubules"
] | [] | [] | [] | Supported | Approved | null | 33 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 25: Non-specific - Transcription | Cluster 72: Neuronal - Signal transduction | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 47: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 217 | 9 |
ENSG00000008438 | PGLYRP1 | Peptidoglycan recognition protein 1 | [
"O75594"
] | 19 | 46019153-46023053 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045702",
"HPA070227"
] | [
"PGLYRP",
"PGRP",
"PGRP-S",
"PGRPS",
"TAG7",
"TNFSF3L"
] | [
"Metabolic proteins",
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Immunity",
"Innate immunity"
] | [
"Antibiotic",
"Antimicrobial"
] | [] | [
"Vesicles"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Secreted to blood"
] | [
"Immunity"
] | Approved | Enhanced | null | 2 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in some | 14 | Low cancer specificity | Detected in some | null | Not detected | Not detected | null | Group enriched | Detected in some | 78 | Group enriched | Detected in some | 202 | 0 | 0 | 0 | [] | [] | [] | 218 | 3 |
ENSG00000008441 | NFIX | Nuclear factor I X | [
"Q14938"
] | 19 | 12995475-13098796 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007533"
] | [
"NF1A"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"DNA replication",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 159 | null | null | Cluster 24: Non-specific - Transcription | Cluster 34: Non-specific - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 108: Fibroblasts - ECM organization | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 219 | 2 |
ENSG00000008513 | ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | [
"Q11201"
] | 8 | 133454848-133571940 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040466"
] | [
"SIAT4A",
"SIATFL",
"ST3GalA.1",
"ST3O"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Glycosyltransferase",
"Transferase"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Approved | null | 4 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 51: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 103: Non-specific - Basic cellular processes | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 220 | 6 |
ENSG00000008516 | MMP25 | Matrix metallopeptidase 25 | [
"Q9NPA2"
] | 16 | 3046062-3060726 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025177",
"HPA055640"
] | [
"MMP20",
"MMPL1",
"MT6-MMP"
] | [
"Enzymes",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [
"Plasma membrane"
] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | Supported | Uncertain | null | null | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 47: Endothelial cells - Vasculature | Cluster 49: HMC-1 - Innate immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 66: Lymphoid tissue - Immune response | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in many | 4 | Cell type enriched | Detected in many | 8 | Group enriched | Detected in some | 5 | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 221 | 2 |
ENSG00000008710 | PKD1 | Polycystin 1, transient receptor potential channel interacting | [
"P98161"
] | 16 | 2088708-2135898 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB046448"
] | [
"PBP",
"Pc-1",
"TRPP1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins",
"Transporters"
] | [
"Wnt signaling pathway"
] | [] | [
"Ciliopathy",
"Disease variant"
] | [] | [] | [
"Secreted - unknown location"
] | [
"Other"
] | null | Approved | null | 12 | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 64: Non-specific - Transcription | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 223 | 8 |
ENSG00000008838 | MED24 | Mediator complex subunit 24 | [
"O75448"
] | 17 | 40019097-40061215 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CRSP100",
"CRSP4",
"DRIP100",
"KIAA0130",
"MED5",
"THRAP4",
"TRAP100"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [] | [] | [] | [] | [] | null | null | null | 86 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 51: Neurons - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 225 | 5 |
ENSG00000008853 | RHOBTB2 | Rho related BTB domain containing 2 | [
"Q9BYZ6"
] | 8 | 22987417-23020509 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA060938"
] | [
"DBC2",
"KIAA0717"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [
"Disease variant",
"Epilepsy"
] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Approved | null | 7 | null | null | Cluster 32: Basophils - Transcription | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 46: Lymphoma - Humoral immune response | Cluster 81: Alveolar cells - Lung function | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Prostate Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Prostate Adenocarcinoma"
] | 226 | 1 |
ENSG00000008869 | HEATR5B | HEAT repeat containing 5B | [
"Q9P2D3"
] | 2 | 36968383-37084372 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036369",
"HPA042025"
] | [
"DKFZp686P15184",
"KIAA1414",
"p200",
"p200a"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Golgi apparatus",
"Vesicles"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Approved | null | 12 | null | null | Cluster 32: Basophils - Transcription | Cluster 9: Non-specific - Receptor signaling | Cluster 55: Lymphoma - Immune response | Cluster 7: Non-specific - Transcription | Cluster 32: Retina & Lymphoid tissues - Signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 227 | 3 |
ENSG00000008952 | SEC62 | SEC62 homolog, preprotein translocation factor | [
"Q99442"
] | 3 | 169966635-169998373 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA014059",
"HPA061450"
] | [
"Dtrp1",
"HTP1",
"TLOC1"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Protein transport",
"Translocation",
"Transport"
] | [] | [] | [
"Endoplasmic reticulum"
] | [
"Intermediate filaments"
] | [] | [] | Approved | Approved | null | 60 | null | null | Cluster 24: Non-specific - Transcription | Cluster 28: Oligodendrocytes - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 8: Non-specific - Secretory pathway | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 228 | 1 |
ENSG00000008988 | RPS20 | Ribosomal protein S20 | [
"P60866"
] | 8 | 56067254-56074510 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003570"
] | [
"S20",
"uS10"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 197 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 229 | 6 |
ENSG00000009307 | CSDE1 | Cold shock domain containing E1 | [
"O75534"
] | 1 | 114716913-114758676 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018846",
"HPA052221"
] | [
"D1S155E",
"UNR"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"RNA-binding"
] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [
"Endoplasmic reticulum",
"Golgi apparatus",
"Plasma membrane"
] | [] | [] | Supported | Supported | null | 26 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 230 | 8 |
ENSG00000009335 | UBE3C | Ubiquitin protein ligase E3C | [
"Q15386"
] | 7 | 157138916-157269370 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039915",
"HPA076403"
] | [
"KIAA0010",
"KIAA10"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Intellectual disability"
] | [
"Cytosol"
] | [
"Vesicles",
"Lipid droplets"
] | [] | [] | Approved | Approved | null | 71 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 50: Non-specific - Nucleic acid binding | Cluster 39: Non-specific - Transcription | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 231 | 1 |
ENSG00000009413 | REV3L | REV3 like, DNA directed polymerase zeta catalytic subunit | [
"O60673"
] | 6 | 111299028-111483715 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA064853",
"HPA069382"
] | [
"POLZ",
"REV3"
] | [
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"DNA replication"
] | [
"DNA-binding",
"DNA-directed DNA polymerase",
"Nucleotidyltransferase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 7 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 28: Non-specific - Nuclear processes | Cluster 108: Fibroblasts - ECM organization | Cluster 42: Retina - Visual perception | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Colon Adenocarcinoma",
"Kidney Chromophobe"
] | [
"Colon Adenocarcinoma",
"Kidney Chromophobe"
] | 232 | 9 |
ENSG00000009694 | TENM1 | Teneurin transmembrane protein 1 | [
"Q9UKZ4"
] | X | 124375903-125204312 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002848",
"HPA063910"
] | [
"ODZ1",
"ODZ3",
"TEN-M1",
"TEN1",
"TNM"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Stress response",
"Transcription",
"Transcription regulation"
] | [
"Neuropeptide",
"Repressor"
] | [] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | [] | Approved | Uncertain | null | 2 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 12: Bone cancer - Neuronal signaling | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 233 | 2 |
ENSG00000009709 | PAX7 | Paired box 7 | [
"P23759"
] | 1 | 18630846-18748866 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"Hup1"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Myogenesis",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant",
"Proto-oncogene"
] | [] | [] | [] | [] | null | null | null | 7 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 30: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in some | 4 | Cancer enriched | Detected in some | 9 | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in some | 39 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 234 | 4 |
ENSG00000009724 | MASP2 | MBL associated serine protease 2 | [
"O00187"
] | 1 | 11022009-11047239 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029313",
"HPA029314"
] | [
"MAP-2",
"Map19",
"MASP1P1",
"sMAP"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted secreted proteins"
] | [
"Complement pathway",
"Immunity",
"Innate immunity"
] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Disease variant"
] | [
"Golgi apparatus"
] | [] | [
"Secreted to blood"
] | [
"Complement pathway"
] | Supported | Uncertain | null | 6 | null | null | null | Cluster 2: Neurons - Nucleosome | Cluster 18: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 31: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 57 | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in some | 144 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 235 | 3 |
ENSG00000009765 | IYD | Iodotyrosine deiodinase | [
"Q6PHW0"
] | 6 | 150368892-150405969 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA059627"
] | [
"C6orf71",
"DEHAL1",
"dJ422F24.1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins"
] | [] | [
"Oxidoreductase"
] | [
"Congenital hypothyroidism",
"Disease variant"
] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 1 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 48: Non-specific - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 33: Thyroid gland - Tissue development | Tissue enriched | Detected in some | 14 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in many | 17 | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 236 | 3 |
ENSG00000009780 | FAM76A | Family with sequence similarity 76 member A | [
"Q8TAV0"
] | 1 | 27725961-27763116 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA044762",
"HPA077897"
] | [
"MGC34648"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 1 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 9: Non-specific - Receptor signaling | Cluster 37: Non-specific - mRNA processing | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 40: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 237 | 2 |
ENSG00000009790 | TRAF3IP3 | TRAF3 interacting protein 3 | [
"Q9Y228"
] | 1 | 209756032-209782320 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040796"
] | [
"T3JAM"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Uncertain | Enhanced | null | 66 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 59: Leukemia - T-cell receptor | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enriched | Detected in many | 4 | Group enriched | Detected in some | 17 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma"
] | 238 | 8 |
ENSG00000009830 | POMT2 | Protein O-mannosyltransferase 2 | [
"Q9UKY4"
] | 14 | 77274956-77320883 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003663"
] | [
"LGMD2N"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [
"Congenital muscular dystrophy",
"Dystroglycanopathy",
"Limb-girdle muscular dystrophy",
"Lissencephaly"
] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 3 | null | null | null | Cluster 13: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 239 | 1 |
ENSG00000009844 | VTA1 | Vesicle trafficking 1 | [
"Q9NP79"
] | 6 | 142147162-142224685 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030968",
"HPA030969"
] | [
"C6orf55",
"HSPC228",
"My012"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Nucleoplasm",
"Vesicles",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 33 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 34: Non-specific - Mixed function | Cluster 28: Non-specific - Nuclear processes | Cluster 7: Non-specific - Transcription | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 240 | 6 |
ENSG00000009950 | MLXIPL | MLX interacting protein like | [
"Q9NP71"
] | 7 | 73593194-73624543 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064640"
] | [
"bHLHd14",
"CHREBP",
"MIO",
"MONDOB",
"WBSCR14",
"WS-bHLH"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [
"Williams-Beuren syndrome"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 5 | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 89: Adipocytes - Lipid metabolism | Cluster 31: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 7 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 241 | 6 |
ENSG00000009954 | BAZ1B | Bromodomain adjacent to zinc finger domain 1B | [
"Q9UIG0"
] | 7 | 73440406-73522293 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB037081",
"CAB037158",
"HPA058068"
] | [
"WBSCR10",
"WBSCR9",
"WSTF"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"DNA damage",
"Transcription",
"Transcription regulation"
] | [
"Kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Williams-Beuren syndrome"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 56 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 55: Non-specific - Transcription | Cluster 39: Non-specific - Transcription | Cluster 27: Non-specific - Cell proliferation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 242 | 1 |
ENSG00000010030 | ETV7 | ETS variant transcription factor 7 | [
"Q9Y603"
] | 6 | 36354091-36387800 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029033"
] | [
"TEL-2",
"TEL2"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 7 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 8: Immune cells - Immune response | Cluster 31: Non-specific - Antiviral immune response | Cluster 106: Spermatogonia - Spermatogonial differentiation | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 3 | 0 | 3 | [
"Head and Neck Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 244 | 8 |
ENSG00000010072 | SPRTN | SprT-like N-terminal domain | [
"Q9H040"
] | 1 | 231337104-231355023 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA025073"
] | [
"C1orf124",
"DKFZP547N043",
"DVC1",
"Spartan"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 46 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 55: Non-specific - Transcription | Cluster 45: Non-specific - Nuclear processes | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 245 | 6 |
ENSG00000010165 | METTL13 | Methyltransferase 13, eEF1A lysine and N-terminal methyltransferase | [
"Q8N6R0"
] | 1 | 171781660-171814023 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA025057",
"HPA044498",
"HPA053705"
] | [
"CGI-01",
"DFNM1",
"EEF1AKNMT",
"FEAT",
"KIAA0859",
"METTL13"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Methyltransferase",
"Multifunctional enzyme",
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 8 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 45: Non-specific - Nuclear processes | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 246 | 9 |
ENSG00000010244 | ZNF207 | Zinc finger protein 207 | [
"O43670"
] | 17 | 32350132-32381885 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017013",
"HPA063908"
] | [
"BuGZ"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Chromosome partition",
"Mitosis"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 10 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 6 | 2 | 5 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 248 | 7 |
ENSG00000010256 | UQCRC1 | Ubiquinol-cytochrome c reductase core protein 1 | [
"P31930"
] | 3 | 48599002-48610976 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002815",
"HPA003525",
"CAB033782"
] | [
"D3S3191",
"QCR1",
"UQCR1"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Electron transport",
"Respiratory chain",
"Transport"
] | [] | [
"Disease variant",
"Neuropathy",
"Parkinsonism"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 56 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 45: Non-specific - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 249 | 6 |
ENSG00000010270 | STARD3NL | STARD3 N-terminal like | [
"O95772"
] | 7 | 38178245-38230670 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019204"
] | [
"MENTHO",
"MGC3251"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | Enhanced | null | 3 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 67: Non-specific - Unknown function | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 43: Placenta - Pregnancy hormone signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 250 | 7 |
ENSG00000010278 | CD9 | CD9 molecule | [
"P21926"
] | 12 | 6199715-6238271 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002490"
] | [
"BA2",
"MIC3",
"MRP-1",
"P24",
"TSPAN29"
] | [
"Cancer-related genes",
"CD markers",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Cell adhesion",
"Fertilization"
] | [] | [
"Cancer-related genes"
] | [
"Plasma membrane"
] | [] | [
"Intracellular and membrane"
] | [
"Cell adhesion"
] | Supported | Supported | null | 20 | null | null | Cluster 41: Basophils - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 26 | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 251 | 4 |
ENSG00000010282 | HHATL | Hedgehog acyltransferase like | [
"Q9HCP6"
] | 3 | 42692663-42702824 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018174"
] | [
"C3orf3",
"GUP1",
"KIAA1173",
"MBOAT3",
"MSTP002",
"OACT3"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 13 | null | null | null | Cluster 28: Oligodendrocytes - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 41: Striated muscle - Muscle contraction | Group enriched | Detected in many | 8 | Cancer enriched | Detected in single | 15 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 252 | 6 |
ENSG00000010292 | NCAPD2 | Non-SMC condensin I complex subunit D2 | [
"Q15021"
] | 12 | 6493356-6531955 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB012423",
"HPA036947",
"HPA037363"
] | [
"CAP-D2",
"CNAP1",
"hCAP-D2",
"KIAA0159"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA condensation",
"Mitosis"
] | [] | [
"Disease variant",
"Primary microcephaly"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Nucleoli",
"Primary cilium",
"Centriolar satellite",
"Basal body"
] | [] | [] | Supported | Approved | null | 37 | null | Yes | Cluster 3: Non-specific - Nuclear processes | Cluster 11: White matter - Signal transduction | Cluster 38: Non-specific - Transcription | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 253 | 9 |
ENSG00000010295 | IFFO1 | Intermediate filament family orphan 1 | [
"Q0D2I5"
] | 12 | 6538961-6556073 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA069344"
] | [
"HOM-TES-103",
"IFFO"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 9 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 37: Neurons - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 254 | 8 |
ENSG00000010310 | GIPR | Gastric inhibitory polypeptide receptor | [
"P48546"
] | 19 | 45668221-45683722 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB022710",
"HPA068054"
] | [] | [
"G-protein coupled receptors",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [
"Vesicles"
] | [] | [] | [] | Uncertain | Uncertain | null | 3 | null | null | null | Cluster 26: Oligodendrocytes - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 96: Enteroendocrine cells - Neuropeptide signaling | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Breast Invasive Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 255 | 5 |
ENSG00000010318 | PHF7 | PHD finger protein 7 | [
"Q9BWX1"
] | 3 | 52410660-52423641 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036283",
"HPA070305"
] | [
"HSPC226",
"NYD-SP6"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm",
"Nuclear speckles"
] | [
"Golgi apparatus"
] | [] | [] | Supported | Enhanced | null | 5 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 37: Neurons - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 6: Testis - Spermatogenesis | Tissue enriched | Detected in many | 213 | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 256 | 5 |
ENSG00000010319 | SEMA3G | Semaphorin 3G | [
"Q9NS98"
] | 3 | 52433035-52445103 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001761"
] | [
"FLJ00014",
"sem2"
] | [
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"Developmental protein"
] | null | Uncertain | null | 1 | null | null | null | Cluster 25: Non-specific - Transcription | Cluster 18: Liver cancer - Metabolism | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 15 | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 257 | 5 |
ENSG00000010322 | NISCH | Nischarin | [
"Q9Y2I1"
] | 3 | 52455118-52493068 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA023189"
] | [
"I-1",
"IRAS",
"KIAA0975"
] | [
"Essential proteins",
"FDA approved drug targets",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [
"Receptor"
] | [
"FDA approved drug targets"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Vesicles",
"Microtubules",
"Cytokinetic bridge"
] | [] | [] | Approved | Approved | null | 37 | Yes | null | Cluster 30: Non-specific - DNA binding | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 8: Non-specific - Basic cellular processes | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 64: Non-specific - Transcription | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 258 | 8 |
ENSG00000010327 | STAB1 | Stabilin 1 | [
"Q9NY15"
] | 3 | 52495338-52524495 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA005434"
] | [
"CLEVER-1",
"FEEL-1",
"FELE-1",
"FEX1",
"KIAA0246",
"SCARH2",
"STAB-1"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Inflammatory response"
] | [
"Receptor"
] | [
"Disease variant"
] | [
"Cytosol"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 12: Non-specific - Vasculature | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 5: Spleen - Immune response | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in single | 65 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 59 | 2 | 0 | 3 | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 259 | 7 |
ENSG00000010361 | FUZ | Fuzzy planar cell polarity protein | [
"Q9BT04"
] | 19 | 49806866-49817376 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041779",
"HPA042196"
] | [
"CPLANE3",
"FLJ22688",
"Fy"
] | [
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cilium biogenesis/degradation",
"Protein transport",
"Transport"
] | [
"Developmental protein"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 8 | No | null | Cluster 29: Non-specific - Unknown function | Cluster 39: Astrocytes - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 260 | 3 |
ENSG00000010379 | SLC6A13 | Solute carrier family 6 member 13 | [
"Q9NSD5"
] | 12 | 220621-262873 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036449",
"HPA052726"
] | [
"GAT2"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Neurotransmitter transport",
"Symport",
"Transport"
] | [] | [] | [
"Mitochondria"
] | [
"Nucleoplasm",
"Nucleoli",
"Cytosol"
] | [] | [] | Supported | null | null | null | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 35: RS4;11 - Unknown function | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 72: Kidney - Transmembrane transport | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 16 | Group enriched | Detected in some | 14 | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 261 | 1 |
ENSG00000010404 | IDS | Iduronate 2-sulfatase | [
"P22304"
] | X | 149476988-149521096 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA078003"
] | [
"ID2S",
"SIDS"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [
"Disease variant",
"Mucopolysaccharidosis"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Approved | null | 61 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 51: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 109: Neurons - Neuronal signaling | Cluster 73: Brain - Neuronal signaling | Tissue enriched | Detected in all | 6 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 262 | 2 |
ENSG00000010438 | PRSS3 | Serine protease 3 | [
"P35030"
] | 9 | 33750679-33799231 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA062452",
"HPA063471"
] | [
"PRSS4",
"TRY3",
"TRY4"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Digestion"
] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [] | [
"Vesicles"
] | [
"Endoplasmic reticulum"
] | [
"Secreted to digestive system"
] | [
"Enzyme"
] | Approved | Supported | null | null | null | null | Cluster 46: Basophils - Proteolysis | Cluster 24: Neurons - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion | Cluster 8: Pancreas - Proteolysis | Tissue enriched | Detected in many | 238 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 6 | Group enriched | Detected in many | 5 | Immune cell enriched | Detected in some | 104 | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 263 | 9 |
ENSG00000010539 | ZNF200 | Zinc finger protein 200 | [
"P98182"
] | 16 | 3222325-3236221 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018981",
"HPA059310"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Uncertain | null | 2 | No | No | Cluster 4: Neutrophils - Degranulation | Cluster 35: Non-specific - DNA binding | Cluster 54: Non-specific - Transcription | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 39: Testis - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 264 | 1 |
ENSG00000010610 | CD4 | CD4 molecule | [
"P01730"
] | 12 | 6786858-6820799 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000011",
"HPA004252",
"HPA004472",
"CAB068180"
] | [] | [
"CD markers",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Adaptive immunity",
"Host-virus interaction",
"Immunity"
] | [
"Host cell receptor for virus entry",
"Receptor"
] | [
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 10 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 51: Myeloma - Immunoglobulins | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in all | null | Group enriched | Detected in some | 35 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 18 | 0 | 0 | 0 | [] | [] | [] | 265 | 4 |
ENSG00000010626 | LRRC23 | Leucine rich repeat containing 23 | [
"Q53EV4"
] | 12 | 6873569-6914241 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037766",
"HPA057533"
] | [
"B7",
"LRPB7"
] | [
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant"
] | [
"Nucleoli",
"Nucleoli rim"
] | [] | [] | [] | Approved | Enhanced | null | 1 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 3: Choroid plexus - Cilium | Cluster 27: Breast cancer - Unknown function | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 266 | 6 |
ENSG00000010671 | BTK | Bruton tyrosine kinase | [
"Q06187"
] | X | 101349338-101390796 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001198",
"HPA002028",
"CAB016689",
"CAB080300"
] | [
"AGMX1",
"ATK",
"IMD1",
"PSCTK1",
"XLA"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Adaptive immunity",
"Apoptosis",
"Immunity",
"Innate immunity",
"Transcription",
"Transcription regulation"
] | [
"Kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes",
"Disease variant",
"Dwarfism",
"FDA approved drug targets"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 41 | null | null | Cluster 32: Basophils - Transcription | Cluster 20: Macrophages & Microglia - Immune response | Cluster 49: HMC-1 - Innate immune response | Cluster 58: Mast cells - Allergic inflammatory responses | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 93 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 4 | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | 267 | 2 |
ENSG00000010704 | HFE | Homeostatic iron regulator | [
"Q30201"
] | 6 | 26087281-26098343 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017276",
"HPA053470"
] | [
"HFE1",
"HLA-H"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [
"Ion transport",
"Iron transport",
"Transport"
] | [] | [
"Disease variant"
] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 6 | No | No | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 36: Choroid plexus - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 268 | 6 |
ENSG00000010803 | SCMH1 | Scm polycomb group protein homolog 1 | [
"Q96GD3"
] | 1 | 41027202-41242306 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048898",
"HPA053292"
] | [
"Scml3"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Cytosol"
] | [] | [] | Supported | null | null | 15 | No | No | Cluster 5: Non-specific - Cell proliferation | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 37: Non-specific - mRNA processing | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 269 | 8 |
ENSG00000010818 | HIVEP2 | HIVEP zinc finger 2 | [
"P31629"
] | 6 | 142751469-142956698 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055954"
] | [
"HIV-EP2",
"MBP-2",
"MIBP1",
"Schnurri-2",
"ZAS2",
"ZNF40B"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 7 | null | null | Cluster 11: T-cells - Unknown function | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 6: Leukemia - Signal transduction | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 271 | 8 |
ENSG00000010932 | FMO1 | Flavin containing dimethylaniline monoxygenase 1 | [
"Q01740"
] | 1 | 171248471-171285978 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA078132"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [
"Monooxygenase",
"Oxidoreductase"
] | [] | [] | [] | [] | [] | null | Approved | null | 5 | null | null | null | null | Cluster 44: Connective tissue cells - ECM organization | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 72: Kidney - Transmembrane transport | Tissue enriched | Detected in many | 10 | Cancer enhanced | Detected in single | null | Group enriched | Detected in many | 8 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Stomach Adenocarcinoma"
] | 272 | 8 |
ENSG00000011009 | LYPLA2 | Lysophospholipase 2 | [
"O95372"
] | 1 | 23791145-23795539 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA063151"
] | [
"APT-2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | null | null | 3 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 36: Choroid plexus - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 274 | 8 |
ENSG00000011021 | CLCN6 | Chloride voltage-gated channel 6 | [
"P51797"
] | 1 | 11806096-11848079 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA032097"
] | [
"CLC-6",
"KIAA0046"
] | [
"Disease related genes",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Antiport",
"Ion transport",
"Transport"
] | [] | [
"Disease variant",
"Neurodegeneration",
"Neuronal ceroid lipofuscinosis"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Uncertain | Approved | null | null | No | No | Cluster 23: B-cells - Immunoglobulins | Cluster 45: Non-specific - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 275 | 8 |
ENSG00000011028 | MRC2 | Mannose receptor C type 2 | [
"Q9UBG0"
] | 17 | 62627670-62693597 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041991"
] | [
"CD280",
"CLEC13E",
"ENDO180",
"KIAA0709"
] | [
"CD markers",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Endocytosis"
] | [
"Receptor"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 7 | null | null | null | Cluster 8: Immune cells - Immune response | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 276 | 5 |
ENSG00000011052 | NME1-NME2 | NME1-NME2 readthrough | [] | 17 | 51153590-51171744 | Evidence at protein level | Evidence at protein level | null | null | [
"CAB002169",
"HPA008467",
"HPA041113",
"CAB076057"
] | [
"NM23-LV",
"NMELV"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 7 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 27: Breast cancer - Unknown function | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 277 | 9 |
ENSG00000011083 | SLC6A7 | Solute carrier family 6 member 7 | [
"Q99884"
] | 5 | 150190062-150222788 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA028907",
"HPA063773"
] | [
"PROT"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Amino-acid transport",
"Neurotransmitter transport",
"Symport",
"Transport"
] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in some | 12 | Cancer enhanced | Detected in single | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 278 | 4 |
ENSG00000011105 | TSPAN9 | Tetraspanin 9 | [
"O75954"
] | 12 | 3077355-3286564 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA014002"
] | [
"NET-5"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Nucleoplasm",
"Golgi apparatus"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 1 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 33: Sarcoma - Muscle contraction | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 64: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 279 | 1 |
ENSG00000011114 | BTBD7 | BTB domain containing 7 | [
"Q9P203"
] | 14 | 93237550-93333092 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049926",
"HPA053406"
] | [
"FLJ10648",
"FUP1"
] | [
"Predicted intracellular proteins"
] | [] | [
"Developmental protein"
] | [] | [
"Focal adhesion sites"
] | [] | [] | [] | Approved | Uncertain | null | 1 | null | null | Cluster 32: Basophils - Transcription | Cluster 25: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 102: Non-specific - Mixed function | Cluster 47: Testis - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 280 | 4 |
ENSG00000011132 | APBA3 | Amyloid beta precursor protein binding family A member 3 | [
"O96018"
] | 19 | 3750772-3761692 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045577"
] | [
"mint3",
"X11L2"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 33 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 11: White matter - Signal transduction | Cluster 23: Non-specific - Transcription | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 281 | 9 |
ENSG00000011143 | MKS1 | MKS transition zone complex subunit 1 | [
"Q9NXB0"
] | 17 | 58205441-58219605 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021372",
"HPA021812"
] | [
"BBS13",
"FLJ20345",
"MKS",
"POC12"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Cilium biogenesis/degradation"
] | [] | [
"Bardet-Biedl syndrome",
"Ciliopathy",
"Disease variant",
"Intellectual disability",
"Joubert syndrome",
"Meckel syndrome",
"Obesity"
] | [
"Nucleoplasm",
"Nucleoli",
"Basal body"
] | [] | [] | [] | Approved | Enhanced | null | 23 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 27: Breast cancer - Unknown function | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 282 | 7 |
ENSG00000011198 | ABHD5 | Abhydrolase domain containing 5, lysophosphatidic acid acyltransferase | [
"Q8WTS1"
] | 3 | 43690108-43734371 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB020685",
"HPA035851",
"HPA035852"
] | [
"CGI-58",
"NCIE2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid metabolism",
"Phospholipid biosynthesis",
"Phospholipid metabolism"
] | [
"Acyltransferase",
"Transferase"
] | [
"Cataract",
"Deafness",
"Disease variant",
"Ichthyosis"
] | [
"Vesicles",
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 20 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 58: Skin - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 283 | 2 |
ENSG00000011201 | ANOS1 | Anosmin 1 | [
"P23352"
] | X | 8528874-8732137 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"ADMLX",
"KAL",
"KAL1",
"KALIG-1",
"WFDC19"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted secreted proteins"
] | [
"Cell adhesion",
"Chemotaxis"
] | [
"Heparin-binding",
"Protease inhibitor",
"Serine protease inhibitor"
] | [
"Disease variant",
"Hypogonadotropic hypogonadism",
"Kallmann syndrome"
] | [] | [] | [
"Secreted in brain"
] | [
"Cell adhesion"
] | null | null | null | 5 | null | null | null | Cluster 22: Non-specific - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 284 | 3 |
ENSG00000011243 | AKAP8L | A-kinase anchoring protein 8 like | [
"Q9ULX6"
] | 19 | 15380050-15419141 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042485",
"HPA042546"
] | [
"HAP95",
"NAKAP95"
] | [
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"mRNA processing",
"mRNA splicing",
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Enhanced | null | 77 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 34: Non-specific - Mixed function | Cluster 40: Non-specific - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 285 | 5 |
ENSG00000011258 | MBTD1 | Mbt domain containing 1 | [
"Q05BQ5"
] | 17 | 51177425-51260163 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021876"
] | [
"FLJ20055",
"SA49P01"
] | [
"Disease related genes",
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 44 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 31: Non-specific - Transcription | Cluster 27: Breast cancer - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Immune cell enhanced | Detected in single | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Rectum Adenocarcinoma"
] | 286 | 6 |
ENSG00000011260 | UTP18 | UTP18 small subunit processome component | [
"Q9Y5J1"
] | 17 | 51260546-51297936 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052378"
] | [
"CGI-48",
"WDR50"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"rRNA processing"
] | [] | [] | [
"Nucleoli",
"Nucleoli rim"
] | [
"Nucleoplasm",
"Nuclear membrane"
] | [] | [] | Supported | Approved | null | 33 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 31: Non-specific - Transcription | Cluster 27: Breast cancer - Unknown function | Cluster 17: Non-specific - RNA processing | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 287 | 1 |
ENSG00000011295 | TTC19 | Tetratricopeptide repeat domain 19 | [
"Q6DKK2"
] | 17 | 15999784-16045015 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023010",
"HPA052380"
] | [
"FLJ20343",
"MGC19520"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Electron transport",
"Respiratory chain",
"Transport"
] | [] | [
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Enhanced | null | 55 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 42: Non-specific - Unknown function | Cluster 103: Non-specific - Basic cellular processes | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 289 | 5 |
ENSG00000011304 | PTBP1 | Polypyrimidine tract binding protein 1 | [
"P26599"
] | 19 | 797075-812327 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013507"
] | [
"HNRNP-I",
"HNRPI",
"pPTB",
"PTB",
"PTB-1",
"PTB2",
"PTB3",
"PTB4"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Activator",
"Repressor",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 69 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 42: Choroid plexus - Mitochondria | Cluster 23: Non-specific - Transcription | Cluster 20: Non-specific - Transcription regulation | Cluster 60: Stomach - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 290 | 7 |
ENSG00000011332 | DPF1 | Double PHD fingers 1 | [
"Q92782"
] | 19 | 38211006-38229714 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049148"
] | [
"BAF45b",
"NEUD4",
"neuro-d4",
"SMARCG1"
] | [
"Predicted intracellular proteins"
] | [
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Mitochondria"
] | [] | [] | Approved | Enhanced | Approved | 30 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 73: Brain - Neuronal signaling | Tissue enriched | Detected in some | 13 | Cancer enhanced | Detected in all | null | Group enriched | Detected in many | 6 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 291 | 8 |
ENSG00000011347 | SYT7 | Synaptotagmin 7 | [
"O43581"
] | 11 | 61513714-61581148 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012869"
] | [
"IPCA-7",
"MGC150517",
"PCANAP7",
"SYT-VII"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Exocytosis"
] | [
"Calmodulin-binding"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 2 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 292 | 2 |
ENSG00000011405 | PIK3C2A | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha | [
"O00443"
] | 11 | 17077730-17207986 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037641",
"HPA037642"
] | [
"PI3K-C2alpha"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Endocytosis",
"Exocytosis",
"Lipid metabolism"
] | [
"Kinase",
"Transferase"
] | [
"Cataract",
"Disease variant",
"Dwarfism"
] | [
"Nucleoplasm"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 49 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 54: Immune cells - T cell receptor | Cluster 24: Non-specific - Unknown function | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 294 | 6 |
ENSG00000011422 | PLAUR | Plasminogen activator, urokinase receptor | [
"Q03405"
] | 19 | 43646095-43670547 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050843",
"CAB073533"
] | [
"CD87",
"UPAR",
"URKR"
] | [
"Cancer-related genes",
"CD markers",
"FDA approved drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [] | [
"Intracellular and membrane"
] | [
"Receptor"
] | Supported | Uncertain | null | 5 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 12: Non-specific - Vasculature | Cluster 72: Neuronal - Signal transduction | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in all | 6 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 3 | 0 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 295 | 9 |
ENSG00000011426 | ANLN | Anillin, actin binding protein | [
"Q9NQW6"
] | 7 | 36389821-36453791 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005680",
"CAB033902",
"HPA050556",
"CAB062547",
"CAB068175"
] | [
"ANILLIN",
"scra",
"Scraps"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [
"Actin-binding"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Midbody"
] | [] | [] | Supported | Enhanced | null | 571 | Yes | Yes | null | Cluster 28: Oligodendrocytes - Mixed function | Cluster 67: Non-specific - Unknown function | Cluster 27: Non-specific - Cell proliferation | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 7 | 8 | 3 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 296 | 5 |
ENSG00000011451 | WIZ | WIZ zinc finger | [
"O95785"
] | 19 | 15419978-15449956 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022923",
"HPA023774"
] | [
"ZNF803"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 48 | null | No | null | Cluster 51: Neurons - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in single | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 297 | 7 |
ENSG00000011454 | RABGAP1 | RAB GTPase activating protein 1 | [
"Q9Y3P9"
] | 9 | 122940833-123104866 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064860",
"HPA072273"
] | [
"GAPCenA",
"TBC1D11"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell cycle"
] | [
"GTPase activation"
] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 22 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 14: Neurons - Synaptic function | Cluster 43: Non-specific - Basic cellular processes | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 298 | 4 |
ENSG00000011465 | DCN | Decorin | [
"P07585"
] | 12 | 91140484-91183217 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003315",
"CAB017118",
"HPA064736",
"CAB068930"
] | [
"DSPG2",
"SLRR1B"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [
"Cancer-related genes",
"Corneal dystrophy"
] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | null | Enhanced | null | 6 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 8: Immune cells - Immune response | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Cancer enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 9 | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 299 | 2 |
ENSG00000011478 | QPCTL | Glutaminyl-peptide cyclotransferase like | [
"Q9NXS2"
] | 19 | 45692403-45703989 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040797"
] | [
"FLJ20084"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Acyltransferase",
"Transferase"
] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | Approved | null | 2 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 63: Non-specific - Protein processing | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 300 | 5 |
ENSG00000011485 | PPP5C | Protein phosphatase 5 catalytic subunit | [
"P53041"
] | 19 | 46347087-46392981 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022641",
"HPA029065",
"HPA056933"
] | [
"PP5",
"PPP5"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"Hydrolase",
"Protein phosphatase"
] | [
"Alzheimer disease",
"Amyloidosis",
"Neurodegeneration"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 62 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 4: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | 301 | 7 |
ENSG00000011523 | CEP68 | Centrosomal protein 68 | [
"Q76N32"
] | 2 | 65056354-65087004 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040493",
"HPA040620"
] | [
"KIAA0582"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Centriolar satellite"
] | [
"Cell Junctions",
"Basal body",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 8 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 38: Sub-cortical - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 302 | 9 |
ENSG00000011566 | MAP4K3 | Mitogen-activated protein kinase kinase kinase kinase 3 | [
"Q8IVH8"
] | 2 | 39249266-39437301 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030380"
] | [
"GLK",
"MAPKKKK3",
"RAB8IPL1"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Cancer-related genes"
] | [
"Centriolar satellite"
] | [] | [] | [] | Approved | Approved | null | 11 | null | null | null | Cluster 31: Non-specific - Transcription | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 303 | 4 |
ENSG00000011590 | ZBTB32 | Zinc finger and BTB domain containing 32 | [
"Q9Y2Y4"
] | 19 | 35704558-35717038 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA076730"
] | [
"FAXF",
"FAZF",
"Rog",
"TZFP",
"ZNF538"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 10 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 55: Lymphoma - Immune response | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in some | 15 | Group enriched | Detected in some | 4 | Not detected | Not detected | null | Group enriched | Detected in many | 5 | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 304 | 6 |
ENSG00000011600 | TYROBP | Transmembrane immune signaling adaptor TYROBP | [
"O43914"
] | 19 | 35904401-35908295 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009493",
"HPA041899"
] | [
"DAP12",
"KARAP",
"PLO-SL",
"PLOSL"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Immunity"
] | [] | [] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 7 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 49: HMC-1 - Innate immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in all | null | Cancer enriched | Detected in some | 26 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Skin Cutaneous Melanoma"
] | [] | [
"Skin Cutaneous Melanoma"
] | 305 | 5 |
ENSG00000011638 | LDAF1 | Lipid droplet assembly factor 1 | [
"Q96B96"
] | 16 | 21158377-21180616 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA018033",
"HPA063509"
] | [
"promethin",
"TMEM159"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 12 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 55: Myocytes - Oxidative muscle function | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 306 | 4 |
ENSG00000011677 | GABRA3 | Gamma-aminobutyric acid type A receptor subunit alpha3 | [
"P34903"
] | X | 152166234-152451315 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000839",
"HPA029363"
] | [] | [
"FDA approved drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Chloride channel",
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"Disease variant",
"Epilepsy",
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | Supported | null | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 32: Non-specific - Cell proliferation | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 1: Choroid plexus - Transmembrane transport | Group enriched | Detected in some | 7 | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in many | 6 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 307 | 8 |
ENSG00000012048 | BRCA1 | BRCA1 DNA repair associated | [
"P38398"
] | 17 | 43044295-43170245 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB001946",
"HPA004840",
"HPA034966",
"HPA057371",
"CAB080453",
"CAB080454"
] | [
"BRCC1",
"FANCS",
"PPP1R53",
"RNF53"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"DNA damage",
"DNA recombination",
"DNA repair",
"Fatty acid biosynthesis",
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid metabolism",
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway"
] | [
"Activator",
"DNA-binding",
"Transferase"
] | [
"Cancer-related genes",
"Disease variant",
"Fanconi anemia",
"Tumor suppressor"
] | [
"Nuclear bodies"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Supported | null | 389 | null | Yes | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 11: White matter - Signal transduction | Cluster 27: Breast cancer - Unknown function | Cluster 27: Non-specific - Cell proliferation | Cluster 51: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 3 | 4 | 1 | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 308 | 2 |
ENSG00000012061 | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit | [
"P07992"
] | 19 | 45407334-45478828 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004390",
"HPA029773",
"HPA050182",
"CAB072859",
"CAB072860"
] | [
"RAD10"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"DNA-binding"
] | [
"Cancer-related genes",
"Cataract"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 31 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 45: Non-specific - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 309 | 4 |
ENSG00000012124 | CD22 | CD22 molecule | [
"P20273"
] | 19 | 35319261-35347361 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002418",
"HPA024353",
"HPA066523"
] | [
"SIGLEC-2",
"SIGLEC2"
] | [
"CD markers",
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | 9 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 11: White matter - Signal transduction | Cluster 46: Lymphoma - Humoral immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 9 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 24 | 1 | 0 | 1 | [
"Prostate Adenocarcinoma"
] | [] | [
"Prostate Adenocarcinoma"
] | 310 | 2 |
ENSG00000012171 | SEMA3B | Semaphorin 3B | [
"Q13214"
] | 3 | 50267558-50277546 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030651"
] | [
"LUCA-1",
"SemA",
"sema5",
"SEMAA",
"semaV"
] | [
"Cancer-related genes",
"Essential proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [
"Cancer-related genes"
] | [] | [] | [
"Secreted in other tissues"
] | [
"Developmental protein"
] | null | Uncertain | null | null | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 69: Skin cancer - ECM organization | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 311 | 1 |
ENSG00000012174 | MBTPS2 | Membrane bound transcription factor peptidase, site 2 | [
"O43462"
] | X | 21839617-21885423 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA005494",
"CAB009486"
] | [
"KFSD",
"S2P"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Cholesterol metabolism",
"Lipid metabolism",
"Steroid metabolism",
"Sterol metabolism"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Disease variant",
"Ichthyosis",
"Osteogenesis imperfecta",
"Palmoplantar keratoderma"
] | [
"Nucleoplasm",
"Mitochondria",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 50: Non-specific - Nucleic acid binding | Cluster 36: Non-specific - mRNA processing | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 28: Liver & Adrenal gland - Secretion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 312 | 4 |
ENSG00000012211 | PRICKLE3 | Prickle planar cell polarity protein 3 | [
"O43900"
] | X | 49174802-49186528 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000998"
] | [
"LMO6"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [
"Developmental protein"
] | [
"Disease variant",
"Leber hereditary optic neuropathy",
"Primary mitochondrial disease"
] | [] | [] | [] | [] | null | Uncertain | null | 19 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 36: Non-specific - mRNA processing | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 313 | 8 |
ENSG00000012223 | LTF | Lactotransferrin | [
"P02788"
] | 3 | 46435645-46485234 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB008646",
"CAB016201",
"HPA057177",
"HPA059976"
] | [
"HLF2"
] | [
"Cancer-related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Immunity",
"Ion transport",
"Iron transport",
"Osteogenesis",
"Transcription",
"Transcription regulation",
"Transport"
] | [
"Antibiotic",
"Antimicrobial",
"DNA-binding",
"Heparin-binding",
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Cancer-related genes"
] | [] | [] | [
"Secreted to blood"
] | [
"Transport"
] | null | Enhanced | null | 20 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 46: Brainstem - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 15: Bone marrow - Innate immune response | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 23 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 314 | 3 |
ENSG00000012232 | EXTL3 | Exostosin like glycosyltransferase 3 | [
"O43909"
] | 8 | 28600469-28756561 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB025387"
] | [
"botv",
"REGR"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosyltransferase",
"Receptor",
"Transferase"
] | [
"Disease variant",
"Dwarfism",
"Intellectual disability"
] | [] | [] | [] | [] | null | Approved | null | 40 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 38: Sub-cortical - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 41: Striated muscle - Muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 315 | 8 |
ENSG00000012504 | NR1H4 | Nuclear receptor subfamily 1 group H member 4 | [
"Q96RI1"
] | 12 | 100473708-100564414 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047699"
] | [
"FXR",
"HRR-1",
"HRR1",
"RIP14"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Nuclear receptors",
"Predicted intracellular proteins",
"Transcription factors",
"Transporters"
] | [
"Immunity",
"Inflammatory response",
"Innate immunity",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Receptor",
"Repressor"
] | [
"Disease variant",
"FDA approved drug targets",
"Intrahepatic cholestasis"
] | [
"Nucleoplasm",
"Nuclear speckles"
] | [
"Primary cilium tip",
"Cytosol"
] | [] | [] | Supported | null | null | 13 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in some | null | Group enriched | Detected in some | 4 | Group enriched | Detected in many | 10 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 316 | 3 |
ENSG00000012660 | ELOVL5 | ELOVL fatty acid elongase 5 | [
"Q9NYP7"
] | 6 | 53267398-53349179 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017042",
"HPA047752",
"HPA054197"
] | [
"dJ483K16.1",
"HELO1",
"SCA38"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Fatty acid biosynthesis",
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid metabolism"
] | [
"Transferase"
] | [
"Disease variant",
"Neurodegeneration",
"Spinocerebellar ataxia"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Enhanced | Enhanced | null | 25 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 317 | 6 |
ENSG00000012779 | ALOX5 | Arachidonate 5-lipoxygenase | [
"P09917"
] | 10 | 45374176-45446119 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA071285"
] | [
"5-LOX"
] | [
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Leukotriene biosynthesis",
"Lipid metabolism"
] | [
"Dioxygenase",
"Hydrolase",
"Oxidoreductase"
] | [
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 21 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 25: Non-specific - Transcription | Cluster 46: Lymphoma - Humoral immune response | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 5: Spleen - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in some | 6 | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 318 | 7 |
ENSG00000012817 | KDM5D | Lysine demethylase 5D | [
"Q9BY66"
] | Y | 19703865-19744939 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049086"
] | [
"HY",
"HYA",
"JARID1D",
"KIAA0234",
"SMCY"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Dioxygenase",
"Oxidoreductase"
] | [] | [
"Nucleoli fibrillar center"
] | [] | [] | [] | Approved | null | null | 4 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 47: Leukemia - Hemostasis | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 5: Spleen - Immune response | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 319 | 6 |
ENSG00000012822 | CALCOCO1 | Calcium binding and coiled-coil domain 1 | [
"Q9P1Z2"
] | 12 | 53708517-53727745 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038313",
"HPA038314"
] | [
"calphoglin",
"Cocoa",
"KIAA1536"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Wnt signaling pathway"
] | [
"Activator"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 33 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 64: Connective tissue cells - ECM organization | Cluster 7: Non-specific - Transcription | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 320 | 1 |
ENSG00000012963 | UBR7 | Ubiquitin protein ligase E3 component n-recognin 7 | [
"Q8N806"
] | 14 | 93207241-93229215 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000861"
] | [
"C14orf130"
] | [
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 23 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 34: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 51: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 16 | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 321 | 9 |
ENSG00000012983 | MAP4K5 | Mitogen-activated protein kinase kinase kinase kinase 5 | [
"Q9Y4K4"
] | 14 | 50418501-50561126 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036696",
"HPA078030"
] | [
"GCKR",
"KHS",
"KHS1"
] | [
"Enzymes",
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Cytosol"
] | [
"Plasma membrane",
"Primary cilium"
] | [] | [] | Supported | Uncertain | null | 16 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 28: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 55: Breast - Lactation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Group enriched | Detected in many | 6 | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 322 | 3 |
ENSG00000013016 | EHD3 | EH domain containing 3 | [
"Q9NZN3"
] | 2 | 31234152-31269451 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049890",
"HPA049986",
"HPA066751"
] | [
"PAST3"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation",
"Protein transport",
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [
"Primary cilium",
"Primary cilium transition zone"
] | [] | [] | Supported | Approved | null | 14 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 51: Neurons - Mixed function | Cluster 20: Myeloma - Immune response | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 10: Brain - Synaptic signal transduction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 323 | 9 |
ENSG00000013288 | MAN2B2 | Mannosidase alpha class 2B member 2 | [
"Q9Y2E5"
] | 4 | 6575189-6623362 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"EpMAN",
"KIAA0935"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Glycosidase",
"Hydrolase"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | null | null | 10 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 23: Choroid plexus - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 108: Fibroblasts - ECM organization | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 325 | 7 |
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