ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000101916
TLR8
Toll like receptor 8
[ "Q9NR97" ]
X
12906620-12923169
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001608" ]
[ "CD288", "hTLR8" ]
[ "CD markers", "Disease related genes", "Predicted membrane proteins" ]
[ "Immunity", "Inflammatory response", "Innate immunity" ]
[ "Receptor" ]
[ "Disease variant" ]
[]
[]
[]
[]
null
Enhanced
null
1
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 20: Macrophages & Microglia - Immune response
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in some
4
Group enriched
Detected in some
73
0
0
0
[]
[]
[]
2,567
5
ENSG00000101928
MOSPD1
Motile sperm domain containing 1
[ "Q9UJG1" ]
X
134887632-134915257
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA031158" ]
[ "dJ473B4" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Differentiation" ]
[]
[]
[ "Nucleoplasm", "Vesicles" ]
[]
[]
[]
Approved
Approved
null
1
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 21: Non-specific - Metabolism
Cluster 36: Non-specific - mRNA processing
Cluster 84: Apical squamous epithelium - Cornification
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
2,568
5
ENSG00000101935
AMMECR1
AMMECR nuclear protein 1
[ "Q9Y4X0" ]
X
110194186-110440318
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000590", "HPA051762" ]
[]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Alport syndrome", "Deafness", "Disease variant", "Elliptocytosis", "Hereditary hemolytic anemia", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Mitochondria" ]
[]
[]
Supported
Uncertain
null
9
null
null
Cluster 16: Non-specific - Cell proliferation
Cluster 23: Choroid plexus - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
4
Low immune cell specificity
Detected in many
null
2
0
2
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
2,569
5
ENSG00000101938
CHRDL1
Chordin like 1
[ "Q9BU40" ]
X
110673856-110795819
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA000226", "HPA000250" ]
[ "CHL", "MGC1", "NRLN1" ]
[ "Disease related genes", "Human disease related genes", "Predicted secreted proteins" ]
[ "Differentiation", "Neurogenesis", "Osteogenesis" ]
[ "Developmental protein" ]
[ "Disease variant" ]
[]
[]
[ "Secreted in other tissues" ]
[ "Developmental protein" ]
null
Approved
null
null
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 44: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
2,570
7
ENSG00000101940
WDR13
WD repeat domain 13
[ "Q9H1Z4" ]
X
48590042-48608869
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000913" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Plasma membrane", "Centriolar satellite" ]
[]
[]
Supported
Supported
null
1
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 51: Neurons - Mixed function
Cluster 36: Non-specific - mRNA processing
Cluster 97: Non-specific - Cellular respiration
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma" ]
2,571
1
ENSG00000101945
SUV39H1
SUV39H1 histone lysine methyltransferase
[ "O43463" ]
X
48695554-48709016
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "KMT1A", "SUV39H" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Biological rhythms", "Cell cycle", "Differentiation", "Host-virus interaction", "rRNA processing", "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "Methyltransferase", "Repressor", "Transferase" ]
[]
[]
[]
[]
[]
null
null
null
147
null
Yes
Cluster 3: Non-specific - Nuclear processes
Cluster 1: Neurons - Mixed function
Cluster 36: Non-specific - mRNA processing
Cluster 27: Non-specific - Cell proliferation
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
2,572
5
ENSG00000101951
PAGE4
PAGE family member 4
[ "O60829" ]
X
49829260-49834264
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023880" ]
[ "CT16.7", "GAGEC1", "PAGE-4" ]
[ "Cancer-related genes", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[ "Cancer-related genes" ]
[ "Vesicles" ]
[ "Golgi apparatus" ]
[]
[]
Approved
Enhanced
null
2
null
null
null
null
Cluster 5: Rhabdoid - Unknown function
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 22: Epididymis - Mixed function
Group enriched
Detected in many
6
Group enriched
Detected in some
5
Group enriched
Detected in some
13
Group enriched
Detected in some
52
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,573
3
ENSG00000101955
SRPX
Sushi repeat containing protein X-linked
[ "P78539" ]
X
38149336-38220924
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "ETX1", "SRPX1" ]
[ "Plasma proteins", "Predicted secreted proteins" ]
[ "Cell adhesion" ]
[]
[]
[]
[]
[ "Secreted - unknown location" ]
[ "Cell adhesion" ]
null
null
null
3
null
null
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
Cluster 44: Non-specific - Mixed function
Cluster 44: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in all
5
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
49
3
0
3
[]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Rectum Adenocarcinoma" ]
2,574
2
ENSG00000101958
GLRA2
Glycine receptor alpha 2
[ "P23416" ]
X
14529298-14731812
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB070422", "HPA078885" ]
[ "GLR" ]
[ "Disease related genes", "FDA approved drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport" ]
[ "Chloride channel", "Ion channel", "Ligand-gated ion channel", "Receptor" ]
[ "Disease variant", "FDA approved drug targets", "Intellectual disability" ]
[ "Vesicles", "Plasma membrane" ]
[]
[]
[]
Approved
Approved
null
null
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 40: Non-specific - Unknown function
Cluster 109: Neurons - Neuronal signaling
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,575
4
ENSG00000101966
XIAP
X-linked inhibitor of apoptosis
[ "P98170" ]
X
123859712-123913972
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB009203", "HPA042428", "HPA047020" ]
[ "API3", "BIRC4", "hILP", "ILP-1" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Apoptosis", "Ubl conjugation pathway", "Wnt signaling pathway" ]
[ "Protease inhibitor", "Thiol protease inhibitor", "Transferase" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[ "Nucleoplasm", "Cytosol" ]
[ "Nucleoli", "Plasma membrane" ]
[]
[]
Supported
Approved
null
163
null
null
Cluster 30: Non-specific - DNA binding
Cluster 21: Non-specific - Metabolism
Cluster 36: Non-specific - mRNA processing
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 42: Retina - Visual perception
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,576
4
ENSG00000101972
STAG2
Stromal antigen 2
[ "Q8N3U4" ]
X
123960212-124422664
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA002857" ]
[ "SA-2", "SA2", "SCC3B" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Chromosome partition", "Meiosis", "Mitosis" ]
[]
[ "Cancer-related genes", "Disease variant", "Holoprosencephaly" ]
[ "Nucleoplasm", "Nucleoli", "Nucleoli fibrillar center" ]
[]
[]
[]
Supported
Supported
null
55
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 55: Non-specific - Transcription
Cluster 36: Non-specific - mRNA processing
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 80: Thymus - Adaptive immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,577
4
ENSG00000101974
ATP11C
ATPase phospholipid transporting 11C
[ "Q8NB49" ]
X
139726346-139945276
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA030830" ]
[ "ATPIG", "ATPIQ" ]
[ "Disease related genes", "Enzymes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Lipid transport", "Transport" ]
[ "Translocase" ]
[ "Disease variant", "Hereditary hemolytic anemia" ]
[]
[]
[]
[]
null
Approved
null
13
null
null
Cluster 14: Non-specific - Unknown function
Cluster 44: Non-specific - Mixed function
Cluster 12: Bone cancer - Neuronal signaling
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 45: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in single
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,578
3
ENSG00000101977
MCF2
MCF.2 cell line derived transforming sequence
[ "P10911" ]
X
139581770-139708216
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB010423" ]
[ "ARHGEF21", "DBL" ]
[ "Disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Guanine-nucleotide releasing factor" ]
[ "Proto-oncogene" ]
[ "Plasma membrane", "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Supported
null
null
6
null
null
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 7: Liver cancer - Metabolism
Cluster 43: Sertoli cells - Spermatogenesis microenvironment
Cluster 4: Adrenal gland - Steroid metabolism
Tissue enhanced
Detected in many
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
2,579
9
ENSG00000101981
F9
Coagulation factor IX
[ "P00740" ]
X
139530739-139563459
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FIX" ]
[ "Candidate cardiovascular disease genes", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted secreted proteins" ]
[ "Blood coagulation", "Hemostasis" ]
[ "Hydrolase", "Protease", "Serine protease" ]
[ "Disease variant", "FDA approved drug targets", "Hemophilia", "Thrombophilia" ]
[]
[]
[ "Secreted to blood" ]
[ "Blood coagulation" ]
null
null
null
null
null
null
null
null
Cluster 10: Ciliated cells - Ion channel activity
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in single
2,787
Not detected
Not detected
null
Cancer enriched
Detected in single
823
Cell type enriched
Detected in some
104
Not detected in immune cells
Not detected
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
2,580
9
ENSG00000101986
ABCD1
ATP binding cassette subfamily D member 1
[ "P33897" ]
X
153724856-153744755
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA035214" ]
[ "adrenoleukodystrophy", "ALD", "ALDP", "AMN" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[ "Hydrolase", "Translocase" ]
[ "Disease variant" ]
[]
[]
[]
[]
null
Approved
null
9
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 18: Non-specific - Mixed function
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
2,581
1
ENSG00000101997
CCDC22
Coiled-coil domain containing 22
[ "O60826" ]
X
49235470-49250520
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000229", "HPA000888", "HPA075980" ]
[ "CXorf37", "JM1" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]
[ "Protein transport", "Transport", "Ubl conjugation pathway" ]
[]
[ "Disease variant", "Intellectual disability" ]
[ "Endoplasmic reticulum" ]
[ "Vesicles" ]
[]
[]
Approved
Uncertain
Approved
109
null
null
Cluster 29: Non-specific - Unknown function
Cluster 6: Non-specific - Immune response
Cluster 36: Non-specific - mRNA processing
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
2,582
6
ENSG00000102001
CACNA1F
Calcium voltage-gated channel subunit alpha1 F
[ "O60840" ]
X
49205063-49233371
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA068379" ]
[ "AIED", "Cav1.4", "CORDX3", "CSNB2", "CSNB2A", "CSNBX2", "JM8", "JMC8", "OA2" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Calcium transport", "Ion transport", "Sensory transduction", "Transport", "Vision" ]
[ "Calcium channel", "Ion channel", "Voltage-gated channel" ]
[ "Cone-rod dystrophy", "Congenital stationary night blindness", "Disease variant", "FDA approved drug targets" ]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 48: Non-specific - Mixed function
Cluster 1: Neuronal - Visual perception
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in some
61
Low cancer specificity
Detected in single
null
Low cancer specificity
Detected in some
null
Group enriched
Detected in some
6
Immune cell enhanced
Detected in single
null
0
0
0
[]
[]
[]
2,583
5
ENSG00000102003
SYP
Synaptophysin
[ "P08247" ]
X
49187815-49200218
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB000076", "HPA002858", "CAB055505", "CAB078999", "HPA079659" ]
[ "MRX96" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[]
[]
[ "Disease variant", "Intellectual disability" ]
[]
[]
[]
[]
null
Enhanced
Supported
67
null
null
Cluster 20: Non-specific - DNA binding
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
6
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
2
0
2
[ "Lung Adenocarcinoma" ]
[ "Rectum Adenocarcinoma" ]
[ "Lung Adenocarcinoma", "Rectum Adenocarcinoma" ]
2,584
7
ENSG00000102007
PLP2
Proteolipid protein 2
[ "Q04941" ]
X
49171898-49175235
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042415" ]
[ "A4", "A4-LSB", "MGC126187" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[]
[]
[]
[]
null
Approved
null
59
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 12: Non-specific - Vasculature
Cluster 36: Non-specific - mRNA processing
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
2,585
9
ENSG00000102010
BMX
BMX non-receptor tyrosine kinase
[ "P51813" ]
X
15464246-15556529
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001048", "CAB032495" ]
[ "ETK", "PSCTK3" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Apoptosis", "Cell adhesion", "Stress response" ]
[ "Kinase", "Transferase", "Tyrosine-protein kinase" ]
[]
[ "Plasma membrane" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Enhanced
null
14
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 42: Choroid plexus - Mitochondria
Cluster 24: Non-specific - Unknown function
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 50: Epididymis - Male reproductive secretion
Tissue enriched
Detected in many
11
Group enriched
Detected in some
6
Cancer enhanced
Detected in many
null
Cell type enriched
Detected in many
4
Immune cell enriched
Detected in single
16
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,586
6
ENSG00000102021
LUZP4
Leucine zipper protein 4
[ "Q9P127" ]
X
115289715-115307563
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046436", "HPA051999" ]
[ "CT-8", "CT28", "HOM-TES-85" ]
[ "Predicted intracellular proteins" ]
[ "mRNA transport", "Transport" ]
[ "RNA-binding" ]
[]
[]
[]
[]
[]
null
Enhanced
null
24
null
null
null
null
Cluster 51: Myeloma - Immunoglobulins
Cluster 106: Spermatogonia - Spermatogonial differentiation
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in single
77
Cancer enhanced
Detected in single
null
Cancer enriched
Detected in some
8
Group enriched
Detected in some
27
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,587
3
ENSG00000102024
PLS3
Plastin 3
[ "P13797" ]
X
115561174-115650861
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA000895", "HPA020433", "HPA076083" ]
[ "T-plastin" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Actin-binding" ]
[ "Disease variant", "Osteoporosis" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
19
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 28: Oligodendrocytes - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
5
3
0
3
[]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
2,588
4
ENSG00000102032
RENBP
Renin binding protein
[ "P51606" ]
X
153935269-153944687
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000428", "HPA000522" ]
[ "RBP", "RNBP" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Isomerase" ]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
Cluster 19: Eosinophils - Unknown function
Cluster 27: Non-specific - Mixed function
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 5: Spleen - Immune response
Tissue enhanced
Detected in many
null
Group enriched
Detected in many
7
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
3
0
3
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
2,590
6
ENSG00000102034
ELF4
E74 like ETS transcription factor 4
[ "Q99607" ]
X
130063955-130110716
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA058595", "HPA060277" ]
[ "ELFR", "MEF" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[ "Cancer-related genes", "Disease variant", "Proto-oncogene" ]
[ "Nuclear bodies" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Enhanced
null
3
null
null
Cluster 33: Non-specific - ATP binding
Cluster 6: Non-specific - Immune response
Cluster 36: Non-specific - mRNA processing
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 15: Bone marrow - Innate immune response
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
2,591
9
ENSG00000102038
SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
[ "P28370" ]
X
129446501-129523500
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003335", "HPA064712" ]
[ "hSNF2L", "ISWI", "NURF140", "SNF2L", "SNF2L1", "SNF2LB", "SWI" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "Chromatin regulator", "Hydrolase" ]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Supported
Uncertain
null
56
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 21: Non-specific - Metabolism
Cluster 5: Rhabdoid - Unknown function
Cluster 94: Gonadal somatic cells - Mixed function
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
3
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma", "Stomach Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma", "Stomach Adenocarcinoma" ]
2,592
9
ENSG00000102043
MTMR8
Myotubularin related protein 8
[ "Q96EF0" ]
X
64268081-64395452
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FLJ20126" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Lipid metabolism" ]
[ "Hydrolase" ]
[]
[]
[]
[]
[]
null
null
null
6
null
null
Cluster 33: Non-specific - ATP binding
Cluster 44: Non-specific - Mixed function
Cluster 36: Non-specific - mRNA processing
Cluster 7: Non-specific - Transcription
Cluster 38: Non-specific - Basic cellular processes
Low tissue specificity
Detected in some
null
Low cancer specificity
Detected in some
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
2,593
9
ENSG00000102048
ASB9
Ankyrin repeat and SOCS box containing 9
[ "Q96DX5" ]
X
15235288-15270467
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003014", "HPA003060", "CAB004997" ]
[ "DKFZP564L0862", "FLJ20636", "MGC4954" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
43
null
null
Cluster 33: Non-specific - ATP binding
Cluster 6: Non-specific - Immune response
Cluster 69: Skin cancer - ECM organization
Cluster 106: Spermatogonia - Spermatogonial differentiation
Cluster 57: Testis - Spermatogenesis
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
2,594
2
ENSG00000102053
ZC3H12B
Zinc finger CCCH-type containing 12B
[ "Q5HYM0" ]
X
65034788-65507887
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA000836" ]
[ "CXorf32", "MCPIP2" ]
[ "Predicted intracellular proteins" ]
[]
[ "Endonuclease", "Hydrolase", "Nuclease" ]
[]
[ "Nucleoli fibrillar center" ]
[ "Golgi apparatus" ]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 36: Non-specific - mRNA processing
Cluster 7: Non-specific - Transcription
Cluster 65: Brain - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in some
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,595
3
ENSG00000102054
RBBP7
RB binding protein 7, chromatin remodeling factor
[ "Q16576" ]
X
16839283-16870362
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB037084", "HPA060710", "HPA060724" ]
[ "RbAp46" ]
[ "Predicted intracellular proteins" ]
[ "DNA replication", "Transcription", "Transcription regulation" ]
[ "Chaperone", "Chromatin regulator", "Repressor" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Supported
null
206
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 31: Non-specific - Transcription
Cluster 36: Non-specific - mRNA processing
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
2,596
3
ENSG00000102055
PPP1R2C
PPP1R2C family member C
[ "O14990" ]
X
42777366-42778163
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "I-4", "PPP1R2P9" ]
[ "Predicted intracellular proteins" ]
[]
[ "Protein phosphatase inhibitor" ]
[]
[]
[]
[]
[]
null
null
null
3
null
null
null
null
null
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in single
209
Not detected
Not detected
null
Cancer enriched
Detected in single
24
Group enriched
Detected in some
10
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,597
5
ENSG00000102057
KCND1
Potassium voltage-gated channel subfamily D member 1
[ "Q9NSA2" ]
X
48961378-48971844
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000524", "HPA001066" ]
[ "Kv4.1" ]
[ "FDA approved drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Ion transport", "Potassium transport", "Transport" ]
[ "Ion channel", "Potassium channel", "Voltage-gated channel" ]
[ "FDA approved drug targets" ]
[ "Nucleoplasm" ]
[]
[]
[]
Uncertain
Supported
null
null
Yes
No
null
Cluster 25: Non-specific - Transcription
Cluster 51: Myeloma - Immunoglobulins
Cluster 108: Fibroblasts - ECM organization
Cluster 64: Non-specific - Transcription
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
2,598
2
ENSG00000102076
OPN1LW
Opsin 1, long wave sensitive
[ "P04000" ]
X
154144243-154159032
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "CBBM", "CBP", "COD5", "RCP" ]
[ "Disease related genes", "G-protein coupled receptors", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Sensory transduction", "Vision" ]
[ "G-protein coupled receptor", "Photoreceptor protein", "Receptor", "Retinal protein", "Transducer" ]
[ "Disease variant" ]
[]
[]
[]
[]
null
null
null
1
null
null
null
null
null
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in single
2,378
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
206
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,599
4
ENSG00000102078
SLC25A14
Solute carrier family 25 member 14
[ "O95258" ]
X
130339888-130373361
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA060316" ]
[ "BMCP1", "UCP5" ]
[ "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
null
null
1
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 14: Neurons - Synaptic function
Cluster 36: Non-specific - mRNA processing
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 1: Choroid plexus - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
2,600
2
ENSG00000102081
FMR1
Fragile X messenger ribonucleoprotein 1
[ "Q06787" ]
X
147911919-147951125
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB012444", "HPA050118", "HPA056084" ]
[ "FMRP", "FRAXA", "MGC87458", "POF", "POF1" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "DNA damage", "Host-virus interaction", "mRNA processing", "mRNA splicing", "mRNA transport", "Neurogenesis", "RNA-mediated gene silencing", "Translation regulation", "Transport" ]
[ "Activator", "Repressor", "Ribonucleoprotein", "RNA-binding" ]
[ "Disease variant", "Intellectual disability", "Neurodegeneration", "Premature ovarian failure" ]
[ "Cytosol" ]
[]
[]
[]
Enhanced
Approved
null
81
null
null
Cluster 33: Non-specific - ATP binding
Cluster 55: Non-specific - Transcription
Cluster 36: Non-specific - mRNA processing
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,601
7
ENSG00000102096
PIM2
Pim-2 proto-oncogene, serine/threonine kinase
[ "Q9P1W9" ]
X
48913182-48919024
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000285" ]
[]
[ "Cancer-related genes", "Enzymes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Apoptosis", "Cell cycle" ]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[ "Cancer-related genes", "Proto-oncogene" ]
[ "Cytosol" ]
[]
[]
[]
Approved
null
null
5
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 29: Forebrain - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 67: Plasma cells - Plasma cell differentiation
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in all
null
Cancer enriched
Detected in all
4
Cancer enriched
Detected in all
7
Cell type enriched
Detected in many
5
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
2,602
1
ENSG00000102098
SCML2
Scm polycomb group protein like 2
[ "Q9UQR0" ]
X
18239313-18354688
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001662", "HPA064713" ]
[]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Repressor" ]
[]
[ "Nucleoli", "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
15
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 31: Non-specific - Transcription
Cluster 6: Leukemia - Signal transduction
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
6
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
2,603
4
ENSG00000102100
SLC35A2
Solute carrier family 35 member A2
[ "P78381" ]
X
48903180-48911958
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036087" ]
[ "UGALT", "UGAT", "UGT", "UGT1", "UGT2", "UGTL" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Antiport", "Sugar transport", "Transport" ]
[]
[ "Congenital disorder of glycosylation", "Disease variant", "Epilepsy" ]
[ "Golgi apparatus" ]
[]
[]
[]
Supported
Approved
null
3
null
null
Cluster 29: Non-specific - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 36: Non-specific - mRNA processing
Cluster 4: Breast lactating luminal cells - Lactation
Cluster 60: Stomach - Digestion
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
2,604
2
ENSG00000102103
PQBP1
Polyglutamine binding protein 1
[ "O60828" ]
X
48890197-48903402
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001880" ]
[ "MRX2", "MRX55", "MRXS3", "MRXS8", "RENS1", "SHS" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Immunity", "Innate immunity", "mRNA processing", "mRNA splicing", "Transcription", "Transcription regulation" ]
[]
[ "Intellectual disability" ]
[ "Nucleoplasm", "Nuclear speckles", "Primary cilium" ]
[ "Microtubules", "Basal body", "Cytosol" ]
[]
[]
Supported
Supported
null
31
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 45: Non-specific - Mixed function
Cluster 36: Non-specific - mRNA processing
Cluster 15: Non-specific - Protein processing
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]
2,605
3
ENSG00000102104
RS1
Retinoschisin 1
[ "O15537" ]
X
18639688-18672108
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA059546" ]
[ "RS", "XLRS1" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted secreted proteins", "Transporters" ]
[ "Cell adhesion", "Sensory transduction", "Vision" ]
[]
[ "Disease variant" ]
[]
[]
[ "Secreted in other tissues" ]
[ "Cell adhesion" ]
null
Enhanced
null
null
null
null
null
null
Cluster 1: Neuronal - Visual perception
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in single
203
Cancer enhanced
Detected in single
null
Not detected
Not detected
null
Group enriched
Detected in some
12
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,606
3
ENSG00000102119
EMD
Emerin
[ "P50402" ]
X
154379273-154381574
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000609", "CAB001545", "CAB002029", "CAB058694", "CAB062552" ]
[ "LEMD5", "STA" ]
[ "Disease related genes", "Human disease related genes", "Predicted membrane proteins" ]
[]
[ "Actin-binding" ]
[ "Cardiomyopathy", "Disease variant", "Emery-Dreifuss muscular dystrophy" ]
[ "Nuclear membrane" ]
[ "Endoplasmic reticulum" ]
[]
[]
Enhanced
Supported
null
194
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 21: Non-specific - Metabolism
Cluster 36: Non-specific - mRNA processing
Cluster 103: Non-specific - Basic cellular processes
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Prostate Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Prostate Adenocarcinoma" ]
2,608
9
ENSG00000102125
TAFAZZIN
Tafazzin, phospholipid-lysophospholipid transacylase
[ "Q16635" ]
X
154411524-154421726
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039557" ]
[ "BTHS", "CMD3A", "EFE", "EFE2", "G4.5", "TAZ", "TAZ1" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Lipid metabolism" ]
[ "Acyltransferase", "Transferase" ]
[ "Cardiomyopathy", "Disease variant" ]
[]
[]
[]
[]
null
Approved
null
10
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 6: Non-specific - Immune response
Cluster 36: Non-specific - mRNA processing
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,609
7
ENSG00000102128
RAB40AL
RAB40A like
[ "P0C0E4" ]
X
102937272-102938300
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA076172" ]
[ "RAR2", "RLGP" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Hydrolase" ]
[]
[ "Vesicles" ]
[]
[]
[]
Uncertain
null
null
2
null
null
null
Cluster 24: Neurons - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 43: Sertoli cells - Spermatogenesis microenvironment
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in single
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,610
1
ENSG00000102144
PGK1
Phosphoglycerate kinase 1
[ "P00558" ]
X
77910739-78129295
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB010065", "HPA045385", "HPA073644", "HPA073656" ]
[]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Glycolysis" ]
[ "Kinase", "Transferase" ]
[ "Disease variant", "Hereditary hemolytic anemia" ]
[ "Mid piece", "Principal piece", "End piece" ]
[]
[]
[]
Approved
Approved
null
47
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 45: Non-specific - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
7
0
7
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
2,611
2
ENSG00000102158
MAGT1
Magnesium transporter 1
[ "Q9H0U3" ]
X
77825747-77899271
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA049851" ]
[ "DKFZp564K142", "IAP", "MRX95", "OST3B", "SLC58A1" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[]
[ "Congenital disorder of glycosylation", "Disease variant" ]
[]
[]
[ "Intracellular and membrane" ]
[ "Transport" ]
null
Approved
null
62
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 30: White matter - Myelination
Cluster 36: Non-specific - mRNA processing
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
2,613
6
ENSG00000102172
SMS
Spermine synthase
[ "P52788" ]
X
21940709-21994837
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA029849", "HPA029852" ]
[ "MRSR", "SPMSY", "SpS", "SRS" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Polyamine biosynthesis" ]
[ "Transferase" ]
[ "Intellectual disability" ]
[ "Nuclear bodies" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
5
No
No
Cluster 7: Non-specific - Innate immune response
Cluster 14: Neurons - Synaptic function
Cluster 36: Non-specific - mRNA processing
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 4: Adrenal gland - Steroid metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
7
2
6
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Breast Invasive Carcinoma", "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Breast Invasive Carcinoma", "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
2,614
3
ENSG00000102178
UBL4A
Ubiquitin like 4A
[ "P11441" ]
X
154483717-154486615
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003617" ]
[ "DXS254E", "GDX", "GET5", "MDY2", "TMA24", "UBL4" ]
[ "Predicted intracellular proteins" ]
[ "Transport" ]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
53
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 36: Non-specific - mRNA processing
Cluster 47: Platelets - Hemostasis
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
5
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
2,616
4
ENSG00000102181
CD99L2
CD99 molecule like 2
[ "Q8TCZ2" ]
X
150766336-150898816
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038782", "HPA038783", "HPA061400" ]
[ "CD99B", "MIC2L1" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins" ]
[ "Cell adhesion" ]
[]
[]
[ "Plasma membrane" ]
[]
[ "Secreted in other tissues" ]
[ "Cell adhesion" ]
Approved
Enhanced
null
11
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 46: Skeletal myocytes - Muscle structure & formation
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
2,617
5
ENSG00000102189
EEA1
Early endosome antigen 1
[ "Q15075" ]
12
92770637-92929331
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005861", "CAB018782", "HPA038158", "HPA038159" ]
[ "ZFYVE2" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Supported
Supported
null
33
null
null
null
Cluster 26: Oligodendrocytes - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe" ]
2,618
9
ENSG00000102218
RP2
RP2 activator of ARL3 GTPase
[ "O75695" ]
X
46837043-46882358
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000234", "HPA000909" ]
[ "NM23-H10", "NME10", "TBCCD2" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[ "GTPase activation" ]
[ "Disease variant", "Retinitis pigmentosa" ]
[ "Plasma membrane", "Mid piece", "Principal piece", "End piece" ]
[ "Nucleoplasm", "Nuclear bodies", "Vesicles", "Cytosol", "Acrosome" ]
[]
[]
Approved
Uncertain
null
39
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 22: Non-specific - Mixed function
Cluster 36: Non-specific - mRNA processing
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 44: Bone marrow - Nuclear processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
2,620
7
ENSG00000102221
JADE3
Jade family PHD finger 3
[ "Q92613" ]
X
46912276-47061242
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006007", "HPA064697" ]
[ "JADE-3", "KIAA0215", "PHF16" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Nucleoli" ]
[]
[]
[]
Approved
Uncertain
null
16
null
null
Cluster 14: Non-specific - Unknown function
Cluster 30: White matter - Myelination
Cluster 36: Non-specific - mRNA processing
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
3
2
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
2,621
2
ENSG00000102225
CDK16
Cyclin dependent kinase 16
[ "Q00536" ]
X
47217860-47229997
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000974", "HPA001366", "CAB016535" ]
[ "FLJ16665", "PCTAIRE", "PCTAIRE1", "PCTGAIRE", "PCTK1" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Microtubules", "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Supported
Approved
null
35
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 32: Cerebral cortex - Mixed function
Cluster 36: Non-specific - mRNA processing
Cluster 65: Non-specific - Cell growth & division
Cluster 19: Skeletal muscle - Striated muscle contraction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
2,622
2
ENSG00000102226
USP11
Ubiquitin specific peptidase 11
[ "P51784" ]
X
47232866-47248328
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003103", "HPA037536" ]
[ "UHX1" ]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Host-virus interaction", "Ubl conjugation pathway" ]
[ "Hydrolase", "Protease", "Thiol protease" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Enhanced
Supported
109
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 36: Non-specific - mRNA processing
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 65: Brain - Transcription
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
2,623
6
ENSG00000102230
PCYT1B
Phosphate cytidylyltransferase 1B, choline
[ "Q9Y5K3" ]
X
24558087-24672677
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA006367" ]
[ "CCT-beta", "CCTbeta", "CTB" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Lipid biosynthesis", "Lipid metabolism", "Phospholipid biosynthesis", "Phospholipid metabolism" ]
[ "Nucleotidyltransferase", "Transferase" ]
[]
[]
[]
[]
[]
null
Uncertain
null
2
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 47: Platelets - Hemostasis
Cluster 73: Brain - Neuronal signaling
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
4
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,624
2
ENSG00000102239
BRS3
Bombesin receptor subtype 3
[ "P32247" ]
X
136487947-136493780
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "BB3", "BB3R", "BBR3" ]
[ "G-protein coupled receptors", "Plasma proteins", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 40: Non-specific - Unknown function
Cluster 10: Epididymal principal cells - Sperm maturation microenvironment
Cluster 50: Epididymis - Male reproductive secretion
Tissue enriched
Detected in some
21
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
9
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,625
7
ENSG00000102241
HTATSF1
HIV-1 Tat specific factor 1
[ "O43719" ]
X
136497079-136512346
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000504" ]
[ "TAT-SF1" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "mRNA processing", "mRNA splicing", "Transcription", "Transcription regulation" ]
[ "Activator", "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Supported
null
41
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 36: Non-specific - mRNA processing
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
2,626
8
ENSG00000102243
VGLL1
Vestigial like family member 1
[ "Q99990" ]
X
136532215-136556807
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042403", "HPA064616" ]
[ "TDU", "TONDU" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Supported
null
17
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 43: Placenta - Pregnancy hormone signaling
Tissue enriched
Detected in many
9
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in many
5
Group enriched
Detected in some
28
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,627
1
ENSG00000102245
CD40LG
CD40 ligand
[ "P29965" ]
X
136648158-136660390
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045827", "HPA072480" ]
[ "CD154", "CD40-L", "CD40L", "gp39", "hCD40L", "HIGM1", "IMD3", "T-BAM", "TNFSF5", "TRAP" ]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "CD markers", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins" ]
[]
[ "Cytokine" ]
[ "Cancer-related genes", "Disease variant" ]
[ "Golgi apparatus", "Plasma membrane" ]
[]
[ "Secreted to blood" ]
[ "Cytokine" ]
Approved
Enhanced
null
1
null
null
Cluster 11: T-cells - Unknown function
Cluster 6: Non-specific - Immune response
Cluster 59: Leukemia - T-cell receptor
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 51: Lymphoid tissue - Adaptive immune response
Tissue enhanced
Detected in some
null
Cancer enriched
Detected in single
7
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in some
null
Group enriched
Detected in many
5
1
0
1
[ "Breast Invasive Carcinoma" ]
[]
[ "Breast Invasive Carcinoma" ]
2,628
5
ENSG00000102265
TIMP1
TIMP metallopeptidase inhibitor 1
[ "P01033" ]
X
47582408-47586789
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB022360", "HPA053417", "CAB080273" ]
[ "CLGI", "EPO", "TIMP" ]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Growth factor", "Metalloenzyme inhibitor", "Metalloprotease inhibitor", "Protease inhibitor" ]
[ "Cancer-related genes" ]
[ "Golgi apparatus", "Vesicles" ]
[]
[ "Secreted to blood" ]
[ "Growth factor" ]
Approved
Approved
null
20
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 12: Non-specific - Vasculature
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
2,629
7
ENSG00000102271
KLHL4
Kelch like family member 4
[ "Q9C0H6" ]
X
87517409-87670050
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029192" ]
[ "DKELCHL", "KHL4", "KIAA1687" ]
[ "Predicted intracellular proteins" ]
[]
[ "Actin-binding" ]
[]
[ "Microtubules", "Primary cilium" ]
[ "Cytokinetic bridge", "Mitotic spindle", "Centriolar satellite", "Centrosome", "Basal body" ]
[]
[]
Supported
Approved
null
6
Yes
null
null
Cluster 11: White matter - Signal transduction
Cluster 48: Adipocytes & Endothelial cells - Angiogenesis
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 4: Adrenal gland - Steroid metabolism
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in some
9
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,630
4
ENSG00000102290
PCDH11X
Protocadherin 11 X-linked
[ "Q9BZA7" ]
X
91779261-92623230
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA000432", "HPA077495" ]
[ "PCDH-X", "PCDH11", "PCDHX", "PPP1R119" ]
[ "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[]
[ "Plasma membrane" ]
[ "Vesicles", "Cytosol" ]
[]
[]
Approved
Approved
null
1
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 3: Rhabdoid - Membrane components
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in single
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
2,632
3
ENSG00000102302
FGD1
FYVE, RhoGEF and PH domain containing 1
[ "P98174" ]
X
54445454-54496234
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000911", "HPA076516" ]
[ "FGDY", "ZFYVE3" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Guanine-nucleotide releasing factor" ]
[ "Disease variant" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Enhanced
Approved
null
2
null
null
null
Cluster 29: Forebrain - Mixed function
Cluster 36: Non-specific - mRNA processing
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
2,633
6
ENSG00000102312
PORCN
Porcupine O-acyltransferase
[ "Q9H237" ]
X
48508959-48520814
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049215", "HPA058413" ]
[ "DHOF", "MG61", "por", "PORC", "PPN" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Wnt signaling pathway" ]
[ "Acyltransferase", "Transferase" ]
[ "Disease variant" ]
[ "Vesicles" ]
[]
[]
[]
Approved
Enhanced
null
null
null
null
Cluster 33: Non-specific - ATP binding
Cluster 51: Neurons - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 4: Adrenal gland - Steroid metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
2,635
2
ENSG00000102313
ITIH6
Inter-alpha-trypsin inhibitor heavy chain family member 6
[ "Q6UXX5" ]
X
54748918-54798255
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA000506" ]
[ "ITIH5L", "UNQ6369" ]
[ "Predicted secreted proteins" ]
[]
[ "Protease inhibitor", "Serine protease inhibitor" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Enzyme inhibitor" ]
null
Uncertain
null
6
null
null
null
null
Cluster 69: Skin cancer - ECM organization
Cluster 36: Skeletal myocytes - Muscle excitation & contraction
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in single
null
Cancer enriched
Detected in single
11
Cancer enriched
Detected in some
8
Cell type enriched
Detected in some
27
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,636
2
ENSG00000102316
MAGED2
MAGE family member D2
[ "Q9UNF1" ]
X
54807599-54816015
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031572", "HPA031573" ]
[ "11B6", "BCG1", "HCA10", "JCL-1", "MAGE-D2", "MAGED", "MGC8386" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Tumor antigen" ]
[ "Bartter syndrome", "Cancer-related genes", "Disease variant" ]
[ "Nucleoplasm", "Nucleoli", "Cytosol" ]
[]
[]
[]
Enhanced
Approved
null
26
No
No
Cluster 42: Non-specific - Vesicular transport
Cluster 49: Hindbrain - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 108: Fibroblasts - ECM organization
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
2,637
2
ENSG00000102349
KLF8
KLF transcription factor 8
[ "O95600" ]
X
56232356-56291531
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA071740" ]
[ "BKLF3", "DXS741", "ZNF741" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
null
null
10
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 31: Non-specific - Transcription
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 58: Skin - Keratinization
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
0
0
0
[]
[]
[]
2,639
5
ENSG00000102359
SRPX2
Sushi repeat containing protein X-linked 2
[ "O60687" ]
X
100644195-100675788
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038786" ]
[ "SRPUL" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Angiogenesis", "Cell adhesion" ]
[]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[]
[]
[ "Secreted to blood" ]
[ "Cell adhesion" ]
null
Approved
null
null
null
null
null
Cluster 46: Brainstem - Mixed function
Cluster 44: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
4
0
4
[ "Rectum Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Stomach Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Rectum Adenocarcinoma", "Stomach Adenocarcinoma" ]
2,640
8
ENSG00000102362
SYTL4
Synaptotagmin like 4
[ "Q96C24" ]
X
100671783-100732123
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA001475", "HPA001589", "HPA075138" ]
[]
[ "Predicted intracellular proteins", "Transporters" ]
[]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Approved
null
39
null
Yes
Cluster 35: Neutrophils - Protein binding
Cluster 46: Brainstem - Mixed function
Cluster 49: HMC-1 - Innate immune response
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
0
0
0
[]
[]
[]
2,641
9
ENSG00000102383
ZDHHC15
Zinc finger DHHC-type palmitoyltransferase 15
[ "Q96MV8" ]
X
75368427-75523502
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003618", "HPA064901" ]
[ "DHHC15", "FLJ31812", "MRX91" ]
[ "Disease related genes", "Enzymes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted membrane proteins" ]
[]
[ "Acyltransferase", "Transferase" ]
[ "Intellectual disability" ]
[ "Nuclear speckles" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
50
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 65: Brain - Transcription
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,642
9
ENSG00000102384
CENPI
Centromere protein I
[ "Q92674" ]
X
101098188-101166126
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA068902", "HPA071514" ]
[ "CENP-I", "FSHPRH1", "LRPR1", "Mis6" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nuclear bodies" ]
[ "Nucleoplasm" ]
[]
[]
Supported
null
null
15
null
Yes
Cluster 7: Non-specific - Innate immune response
Cluster 6: Non-specific - Immune response
Cluster 36: Non-specific - mRNA processing
Cluster 27: Non-specific - Cell proliferation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
4
2
3
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
2,643
8
ENSG00000102385
DRP2
Dystrophin related protein 2
[ "Q13474" ]
X
101219769-101264502
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA002949" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nuclear speckles", "Plasma membrane" ]
[]
[]
[]
Approved
null
null
2
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 48: Adipocytes & Endothelial cells - Angiogenesis
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 78: Brain - Neuronal signaling
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Cancer enhanced
Detected in single
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
2,644
2
ENSG00000102387
TAF7L
TATA-box binding protein associated factor 7 like
[ "Q5H9L4" ]
X
101268253-101293057
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA001879", "HPA072008" ]
[ "CT40", "TAF2Q" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis", "Transcription", "Transcription regulation" ]
[ "Developmental protein" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
4
null
null
null
Cluster 23: Choroid plexus - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 43: Sertoli cells - Spermatogenesis microenvironment
Cluster 56: Ciliated tissues - Cilium organization
Tissue enriched
Detected in some
8
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enriched
Detected in some
5
Not detected in immune cells
Not detected
null
1
0
1
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
2,645
4
ENSG00000102390
PBDC1
Polysaccharide biosynthesis domain containing 1
[ "Q9BVG4" ]
X
76173040-76178314
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003155" ]
[ "CXorf26", "MGC874" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Nucleoli", "Cytosol" ]
[]
[]
Approved
Uncertain
null
4
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 36: Non-specific - mRNA processing
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 49: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
2,646
9
ENSG00000102393
GLA
Galactosidase alpha
[ "P06280" ]
X
101393273-101408012
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000237", "HPA000966" ]
[ "GALA" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Lipid metabolism" ]
[ "Glycosidase", "Hydrolase" ]
[ "Disease variant" ]
[]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
null
Enhanced
null
10
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 21: Non-specific - Metabolism
Cluster 7: Liver cancer - Metabolism
Cluster 103: Non-specific - Basic cellular processes
Cluster 69: Parathyroid gland - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
2,647
3
ENSG00000102401
ARMCX3
Armadillo repeat containing X-linked 3
[ "Q9UH62" ]
X
101622797-101627843
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA000325", "HPA000967", "HPA001530" ]
[ "ALEX3", "GASP6" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Golgi apparatus", "Cytosol" ]
[]
[]
Approved
Uncertain
null
17
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 27: Non-specific - Mixed function
Cluster 36: Non-specific - mRNA processing
Cluster 58: Mast cells - Allergic inflammatory responses
Cluster 38: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
2,648
1
ENSG00000102409
BEX4
Brain expressed X-linked 4
[ "Q9NWD9" ]
X
103215108-103217246
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045105", "HPA051935" ]
[ "BEXL1", "FLJ10097" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Supported
Uncertain
null
1
null
null
Cluster 41: Basophils - Unknown function
Cluster 14: Neurons - Synaptic function
Cluster 47: Leukemia - Hemostasis
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
6
0
6
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
2,649
3
ENSG00000102445
RUBCNL
Rubicon like autophagy enhancer
[ "Q9H714" ]
13
46334681-46438190
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA026614" ]
[ "C13orf18", "FLJ21562", "KIAA0226L", "PACER" ]
[ "Predicted intracellular proteins" ]
[ "Autophagy", "Lipid metabolism" ]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
4
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 20: Macrophages & Microglia - Immune response
Cluster 46: Lymphoma - Humoral immune response
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 18: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in many
5
Group enriched
Detected in many
5
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
15
2
0
2
[ "Bladder Urothelial Carcinoma", "Colon Adenocarcinoma" ]
[]
[ "Bladder Urothelial Carcinoma", "Colon Adenocarcinoma" ]
2,650
5
ENSG00000102452
NALCN
Sodium leak channel, non-selective
[ "Q8IZF0" ]
13
101053776-101416508
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA031889", "HPA031890", "HPA031958" ]
[ "bA430M15.1", "CanIon", "VGCNL1" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Sodium transport", "Transport" ]
[ "Ion channel", "Sodium channel", "Voltage-gated channel" ]
[ "Disease variant", "Neurodegeneration" ]
[ "Microtubules", "Primary cilium", "Cytosol" ]
[ "Nucleoli", "Plasma membrane", "Cytokinetic bridge", "Mitotic spindle" ]
[]
[]
Uncertain
Approved
null
1
Yes
null
Cluster 32: Basophils - Transcription
Cluster 34: Non-specific - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
5
1
0
1
[]
[ "Stomach Adenocarcinoma" ]
[ "Stomach Adenocarcinoma" ]
2,651
1
ENSG00000102466
FGF14
Fibroblast growth factor 14
[ "Q92915" ]
13
101710804-102402457
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA049828" ]
[ "FHF4", "SCA27" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[ "Growth factor" ]
[ "Disease variant", "Neurodegeneration", "Spinocerebellar ataxia" ]
[ "Nucleoli fibrillar center" ]
[]
[]
[]
Approved
null
null
2
null
null
null
Cluster 2: Neurons - Nucleosome
Cluster 10: Ciliated cells - Ion channel activity
Cluster 2: Cerebellar granular cells - Neuronal signaling
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,652
8
ENSG00000102468
HTR2A
5-hydroxytryptamine receptor 2A
[ "P28223" ]
13
46831546-46897076
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA014011" ]
[ "5-HT2A", "HTR2" ]
[ "FDA approved drug targets", "G-protein coupled receptors", "Human disease related genes", "Predicted membrane proteins", "Transporters" ]
[ "Behavior", "Host-virus interaction" ]
[ "G-protein coupled receptor", "Host cell receptor for virus entry", "Receptor", "Transducer" ]
[ "FDA approved drug targets" ]
[]
[]
[]
[]
null
Enhanced
null
5
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 2: Mucus-secreting cells - Unknown function
Cluster 109: Neurons - Neuronal signaling
Cluster 73: Brain - Neuronal signaling
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in single
null
Cancer enhanced
Detected in single
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,653
3
ENSG00000102471
NDFIP2
Nedd4 family interacting protein 2
[ "Q9NV92" ]
13
79481155-79556077
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA009160" ]
[ "KIAA1165", "N4wbp5a" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Supported
Uncertain
null
10
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 51: Neurons - Mixed function
Cluster 19: Non-specific - Unknown function
Cluster 84: Apical squamous epithelium - Cornification
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Head and Neck Squamous Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
2,654
6
ENSG00000102524
TNFSF13B
TNF superfamily member 13b
[ "Q9Y275" ]
13
108251240-108308484
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB009188", "HPA030526" ]
[ "BAFF", "BLYS", "CD257", "TALL-1", "TALL1", "THANK", "TNFSF20" ]
[ "Cancer-related genes", "CD markers", "FDA approved drug targets", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins" ]
[ "Immunity" ]
[ "Cytokine" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[ "Plasma membrane" ]
[ "Vesicles", "Focal adhesion sites" ]
[ "Secreted to blood" ]
[ "Cytokine" ]
Supported
Enhanced
null
27
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 8: Immune cells - Immune response
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in some
10
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,655
1
ENSG00000102531
FNDC3A
Fibronectin type III domain containing 3A
[ "Q9Y2H6" ]
13
48975912-49209779
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA008927", "HPA012555", "HPA012825" ]
[ "bA203I16.5", "FNDC3", "KIAA0970" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Golgi apparatus", "Centrosome" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
10
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 19: Non-specific - Unknown function
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
2,656
5
ENSG00000102539
MLNR
Motilin receptor
[ "O43193" ]
13
49220338-49222377
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA070324" ]
[ "GPR38" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
null
null
null
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 44: Bone marrow - Nuclear processes
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Cancer enriched
Detected in single
5
Cell type enhanced
Detected in single
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,657
2
ENSG00000102543
CDADC1
Cytidine and dCMP deaminase domain containing 1
[ "Q9BWV3" ]
13
49247925-49293485
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA047615", "HPA058314" ]
[ "NYD-SP15" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
null
No
No
Cluster 42: Non-specific - Vesicular transport
Cluster 38: Sub-cortical - Mixed function
Cluster 19: Non-specific - Unknown function
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
4
Immune cell enriched
Detected in many
5
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
2,658
4
ENSG00000102547
CAB39L
Calcium binding protein 39 like
[ "Q9H9S4" ]
13
49308650-49444064
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB003686", "HPA045954", "HPA076632" ]
[ "bA103J18.3", "FLJ12577", "MO2L" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Approved
null
6
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 3: Choroid plexus - Cilium
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid
Cluster 1: Choroid plexus - Transmembrane transport
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
2,659
4
ENSG00000102554
KLF5
KLF transcription factor 5
[ "Q13887" ]
13
73054976-73077541
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040398" ]
[ "BTEB2", "CKLF", "IKLF" ]
[ "Cancer-related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm" ]
[ "Golgi apparatus", "Vesicles" ]
[]
[]
Supported
Approved
null
38
null
null
Cluster 46: Basophils - Proteolysis
Cluster 33: Neurons - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in some
20
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
2,660
1
ENSG00000102572
STK24
Serine/threonine kinase 24
[ "Q9Y6E0" ]
13
98445185-98577940
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA026435", "HPA026502" ]
[ "MST-3", "MST3", "MST3B", "STE20", "STK3" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Apoptosis" ]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nucleoli", "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
57
No
No
Cluster 10: Non-specific - Membrane trafficking
Cluster 23: Choroid plexus - Mixed function
Cluster 19: Non-specific - Unknown function
Cluster 103: Non-specific - Basic cellular processes
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
4
4
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
2,661
3
ENSG00000102575
ACP5
Acid phosphatase 5, tartrate resistant
[ "P13686" ]
19
11574653-11579993
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002584", "HPA057655", "HPA059463" ]
[ "HPAP", "TRAcP", "TRAP" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[ "Disease variant" ]
[ "Cytosol" ]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Uncertain
Enhanced
null
2
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 12: Non-specific - Vasculature
Cluster 69: Skin cancer - ECM organization
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 5: Spleen - Immune response
Tissue enhanced
Detected in all
null
Cancer enriched
Detected in many
7
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,662
6
ENSG00000102580
DNAJC3
DnaJ heat shock protein family (Hsp40) member C3
[ "Q13217" ]
13
95677139-95794988
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039336", "HPA041326" ]
[ "ERdj6", "HP58", "P58", "p58(IPK)", "P58IPK", "PRKRI" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Antiviral defense", "Stress response", "Translation regulation", "Unfolded protein response" ]
[ "Chaperone", "Repressor" ]
[ "Deafness", "Diabetes mellitus", "Neurodegeneration", "Neuropathy" ]
[ "Endoplasmic reticulum" ]
[]
[ "Intracellular and membrane" ]
[ "Defense" ]
Approved
Uncertain
null
34
null
null
Cluster 41: Basophils - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 63: Non-specific - Protein processing
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,663
8
ENSG00000102595
UGGT2
UDP-glucose glycoprotein glucosyltransferase 2
[ "Q9NYU1" ]
13
95801580-96053482
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA047955" ]
[ "FLJ10873", "FLJ11485", "HUGT2", "MGC117360", "MGC150689", "MGC87276", "UGCGL2" ]
[ "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Glycosyltransferase", "Transferase" ]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
null
Uncertain
null
19
null
null
Cluster 25: Non-specific - Unknown function
Cluster 9: Non-specific - Receptor signaling
Cluster 19: Non-specific - Unknown function
Cluster 7: Non-specific - Transcription
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Group enriched
Detected in many
4
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
2,664
9
ENSG00000102606
ARHGEF7
Rho guanine nucleotide exchange factor 7
[ "Q14155" ]
13
111114559-111305737
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA004744" ]
[ "BETA-PIX", "COOL1", "DKFZp686C12170", "DKFZp761K1021", "KIAA0142", "Nbla10314", "P50", "P50BP", "P85", "P85COOL1", "P85SPR", "PAK3", "PIXB" ]
[ "Predicted intracellular proteins" ]
[ "Neurogenesis" ]
[ "Guanine-nucleotide releasing factor" ]
[]
[]
[]
[]
[]
null
Approved
null
66
null
null
Cluster 22: Eosinophils - Transcription
Cluster 34: Non-specific - Mixed function
Cluster 19: Non-specific - Unknown function
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Bladder Urothelial Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Bladder Urothelial Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
2,665
5
ENSG00000102678
FGF9
Fibroblast growth factor 9
[ "P31371" ]
13
21671073-21704498
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA067007" ]
[]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted secreted proteins", "RAS pathway related proteins" ]
[ "Differentiation" ]
[ "Developmental protein", "Growth factor", "Heparin-binding", "Mitogen" ]
[ "Cancer-related genes", "Deafness", "Disease variant" ]
[]
[]
[ "Secreted in other tissues" ]
[ "Growth factor" ]
null
Enhanced
Approved
1
null
null
null
Cluster 37: Neurons - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 11: Muller glia cells - Retinal homeostasis
Cluster 36: Brain & Liver - Signaling
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in some
5
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
2,666
8
ENSG00000102683
SGCG
Sarcoglycan gamma
[ "Q13326" ]
13
23180979-23325162
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA007476" ]
[ "A4", "DAGA4", "DMDA", "DMDA1", "LGMD2C", "MAM", "MGC130048", "SCARMD2", "SCG3", "TYPE" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted membrane proteins" ]
[]
[]
[ "Disease variant", "Limb-girdle muscular dystrophy" ]
[]
[]
[]
[]
null
Enhanced
null
14
null
null
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 5: Rhabdoid - Unknown function
Cluster 46: Skeletal myocytes - Muscle structure & formation
Cluster 41: Striated muscle - Muscle contraction
Group enriched
Detected in many
10
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,667
7
ENSG00000102710
SUPT20H
SPT20 homolog, SAGA complex component
[ "Q8NEM7" ]
13
37009312-37059713
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038906", "HPA038907" ]
[ "bA421P11.4", "C13orf19", "FAM48A", "P38IP", "SPT20" ]
[ "Predicted intracellular proteins" ]
[ "Autophagy", "Gastrulation" ]
[ "Developmental protein" ]
[]
[ "Nucleoli fibrillar center" ]
[]
[]
[]
Approved
Uncertain
null
59
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 55: Non-specific - Transcription
Cluster 19: Non-specific - Unknown function
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 39: Testis - Nuclear processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
2,669
1
ENSG00000102738
MRPS31
Mitochondrial ribosomal protein S31
[ "Q92665" ]
13
40729128-40771190
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039083", "HPA046344" ]
[ "IMOGN38" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[]
[ "Mitochondria" ]
[ "Nucleoli" ]
[]
[]
Supported
Uncertain
null
98
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 28: Oligodendrocytes - Mixed function
Cluster 19: Non-specific - Unknown function
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
2,670
5
ENSG00000102743
SLC25A15
Solute carrier family 25 member 15
[ "Q9Y619" ]
13
40789412-40812460
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042146" ]
[ "D13S327", "HHH", "ORC1", "ORNT1" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[]
[ "Disease variant" ]
[]
[]
[]
[]
null
Approved
null
20
null
null
Cluster 20: Non-specific - DNA binding
Cluster 26: Oligodendrocytes - Mixed function
Cluster 19: Non-specific - Unknown function
Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio
Cluster 45: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Liver Hepatocellular Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
2,671
8
ENSG00000102753
KPNA3
Karyopherin subunit alpha 3
[ "O00505" ]
13
49699320-49792682
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046852", "HPA077643" ]
[ "hSRP1", "IPOA4", "SRP1gamma", "SRP4" ]
[ "Human disease related genes", "Predicted intracellular proteins", "Transporters" ]
[ "Host-virus interaction", "Protein transport", "Transport", "Viral penetration into host nucleus", "Virus entry into host cell" ]
[]
[ "Disease variant", "Hereditary spastic paraplegia", "Neurodegeneration" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
112
null
null
Cluster 33: Non-specific - ATP binding
Cluster 27: Non-specific - Mixed function
Cluster 19: Non-specific - Unknown function
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,672
7
ENSG00000102755
FLT1
Fms related receptor tyrosine kinase 1
[ "P17948" ]
13
28300346-28495145
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011740", "HPA014290", "CAB068189", "CAB068190" ]
[ "FLT", "VEGFR1" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "FDA approved drug targets", "Plasma proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins" ]
[ "Angiogenesis", "Chemotaxis", "Differentiation" ]
[ "Developmental protein", "Kinase", "Receptor", "Transferase", "Tyrosine-protein kinase" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[ "Plasma membrane" ]
[ "Actin filaments", "Cytosol" ]
[ "Secreted to blood" ]
[ "Receptor" ]
Supported
Enhanced
null
21
null
null
null
Cluster 47: Endothelial cells - Vasculature
Cluster 49: HMC-1 - Innate immune response
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 43: Placenta - Pregnancy hormone signaling
Tissue enriched
Detected in many
9
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
2,673
5
ENSG00000102760
RGCC
Regulator of cell cycle
[ "Q9H4X1" ]
13
41457550-41470871
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035638", "HPA063701" ]
[ "bA157L14.2", "C13orf15", "RGC-32", "RGC32" ]
[ "Predicted intracellular proteins" ]
[ "Cell cycle" ]
[]
[]
[ "Nucleoplasm" ]
[ "Nucleoli" ]
[]
[]
Supported
Enhanced
null
3
No
No
Cluster 31: T-cells - T-cell receptor
Cluster 13: Oligodendrocytes - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
2,674
7
ENSG00000102763
VWA8
Von Willebrand factor A domain containing 8
[ "A3KMH1" ]
13
41566835-41961120
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039075", "HPA045478" ]
[ "KIAA0564", "P7BP2" ]
[ "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Retinitis pigmentosa" ]
[ "Vesicles", "Lipid droplets" ]
[]
[]
[]
Approved
Uncertain
null
20
null
null
Cluster 1: T-cells - Unknown function
Cluster 50: Non-specific - Nucleic acid binding
Cluster 19: Non-specific - Unknown function
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
2,675
1