ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000100629 | CEP128 | Centrosomal protein 128 | [
"Q6ZU80"
] | 14 | 80476983-80959517 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001116",
"HPA005846",
"HPA018498"
] | [
"C14orf145",
"C14orf61"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Centrosome"
] | [] | [] | [] | Supported | Uncertain | null | 14 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 54: Immune cells - T cell receptor | Cluster 51: Myeloma - Immunoglobulins | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 80: Thymus - Adaptive immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 2,339 | 9 |
ENSG00000100632 | ERH | ERH mRNA splicing and mitosis factor | [
"P84090"
] | 14 | 69380128-69398299 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002567"
] | [
"DROER"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 65 | null | Yes | Cluster 30: Non-specific - DNA binding | Cluster 21: Non-specific - Metabolism | Cluster 30: Non-specific - Gene expression regulation | Cluster 97: Non-specific - Cellular respiration | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,340 | 5 |
ENSG00000100647 | SUSD6 | Sushi domain containing 6 | [
"Q92537"
] | 14 | 69611596-69715144 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003419",
"HPA030464"
] | [
"KIAA0247"
] | [
"Predicted membrane proteins"
] | [] | [] | [
"Tumor suppressor"
] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 7 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 25: Non-specific - Transcription | Cluster 70: DU4475 - Unknown function | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,342 | 5 |
ENSG00000100650 | SRSF5 | Serine and arginine rich splicing factor 5 | [
"Q13243"
] | 14 | 69726900-69772005 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043484",
"HPA056523"
] | [
"HRS",
"SFRS5",
"SRP40"
] | [
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Cytosol"
] | [] | [] | Supported | Approved | null | 122 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 42: Choroid plexus - Mitochondria | Cluster 30: Non-specific - Gene expression regulation | Cluster 84: Apical squamous epithelium - Cornification | Cluster 15: Bone marrow - Innate immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,343 | 8 |
ENSG00000100652 | SLC10A1 | Solute carrier family 10 member 1 | [
"Q14973"
] | 14 | 69775416-69797241 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042727"
] | [
"NTCP",
"NTCP1"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Host-virus interaction",
"Ion transport",
"Lipid transport",
"Sodium transport",
"Symport",
"Transport"
] | [
"Host cell receptor for virus entry",
"Receptor"
] | [
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Approved | null | 85 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 34: Testis cancer - Unknown function | Cluster 20: Non-specific - Transcription regulation | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in single | 1,060 | Not detected | Not detected | null | Cancer enriched | Detected in single | 343 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 2,344 | 2 |
ENSG00000100664 | EIF5 | Eukaryotic translation initiation factor 5 | [
"P55010"
] | 14 | 103333544-103345025 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000867",
"CAB004226"
] | [] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"GTPase activation",
"Initiation factor"
] | [] | [
"Cytosol"
] | [
"Plasma membrane",
"Primary cilium",
"Primary cilium tip"
] | [] | [] | Approved | Supported | null | 96 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 27: Non-specific - Mixed function | Cluster 20: Myeloma - Immune response | Cluster 20: Non-specific - Transcription regulation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 2,345 | 8 |
ENSG00000100665 | SERPINA4 | Serpin family A member 4 | [
"P29622"
] | 14 | 94561442-94569913 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003607",
"HPA068939"
] | [
"KAL",
"KLST",
"KST",
"PI4"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Protease inhibitor",
"Serine protease inhibitor"
] | [] | [
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Enzyme inhibitor"
] | Uncertain | Approved | null | 3 | null | null | null | null | Cluster 18: Liver cancer - Metabolism | Cluster 97: Non-specific - Cellular respiration | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 4 | Group enriched | Detected in some | 5 | Group enriched | Detected in many | 8 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,346 | 4 |
ENSG00000100678 | SLC8A3 | Solute carrier family 8 member A3 | [
"P57103"
] | 14 | 70044215-70189480 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001669"
] | [
"NCX3"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Calcium transport",
"Ion transport",
"Sodium transport",
"Transport"
] | [
"Calmodulin-binding"
] | [] | [
"Cytosol",
"Acrosome",
"End piece"
] | [
"Nucleoplasm",
"Centrosome"
] | [] | [] | Supported | null | null | null | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 19: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in some | 10 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in single | 8 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,347 | 7 |
ENSG00000100697 | DICER1 | Dicer 1, ribonuclease III | [
"Q9UPY3"
] | 14 | 95086228-95158010 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000694",
"CAB068185"
] | [
"Dicer",
"HERNA",
"K12H4.8-LIKE",
"KIAA0928",
"MNG1"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"RNA-mediated gene silencing"
] | [
"Endonuclease",
"Helicase",
"Hydrolase",
"Nuclease",
"RNA-binding"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 62 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 11: White matter - Signal transduction | Cluster 30: Non-specific - Gene expression regulation | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,348 | 9 |
ENSG00000100711 | ZFYVE21 | Zinc finger FYVE-type containing 21 | [
"Q9BQ24"
] | 14 | 103715730-103733668 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA055721"
] | [
"MGC2550",
"ZF21"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 26 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 2,349 | 4 |
ENSG00000100714 | MTHFD1 | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 | [
"P11586"
] | 14 | 64388031-64463457 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000704",
"HPA001290",
"HPA015006",
"HPA050052"
] | [
"MTHFC",
"MTHFD"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"One-carbon metabolism"
] | [
"Hydrolase",
"Ligase",
"Multifunctional enzyme",
"Oxidoreductase"
] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 20 | null | Yes | Cluster 14: Non-specific - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 89: Adipocytes - Lipid metabolism | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in all | 6 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,350 | 3 |
ENSG00000100721 | TCL1A | TCL1 family AKT coactivator A | [
"P56279"
] | 14 | 95709947-95714196 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004045",
"HPA016604"
] | [
"TCL1"
] | [
"Cancer-related genes",
"Disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Endoplasmic reticulum",
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | Enhanced | null | 50 | null | null | Cluster 34: B-cells - Unknown function | null | Cluster 46: Lymphoma - Humoral immune response | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 18: Lymphoid tissue - Immune response | Tissue enriched | Detected in some | 13 | Group enriched | Detected in some | 187 | Cancer enriched | Detected in many | 21 | Cell type enriched | Detected in some | 4 | Group enriched | Detected in many | 295 | 2 | 0 | 2 | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma"
] | 2,351 | 2 |
ENSG00000100722 | ZC3H14 | Zinc finger CCCH-type containing 14 | [
"Q6PJT7"
] | 14 | 88562970-88627596 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049798",
"HPA053510"
] | [
"FLJ11806",
"NY-REN-37",
"UKp68"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis"
] | [
"RNA-binding"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nuclear speckles"
] | [
"Nucleoli",
"Nucleoli rim"
] | [] | [] | Enhanced | Enhanced | null | 8 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 31: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 47: Testis - Mixed function | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 2,352 | 9 |
ENSG00000100726 | TELO2 | Telomere maintenance 2 | [
"Q9Y4R8"
] | 16 | 1493344-1510457 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041348",
"HPA041473"
] | [
"hCLK2",
"KIAA0683",
"TEL2"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Nuclear bodies",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 44 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 25: Non-specific - Transcription | Cluster 54: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 2,353 | 2 |
ENSG00000100731 | PCNX1 | Pecanex 1 | [
"Q96RV3"
] | 14 | 70907405-71115382 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048970",
"HPA053532"
] | [
"KIAA0805",
"KIAA0995",
"PCNX",
"PCNXL1",
"pecanex"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | null | null | null | Cluster 33: Non-specific - ATP binding | Cluster 14: Neurons - Synaptic function | Cluster 30: Non-specific - Gene expression regulation | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 4 | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 2,354 | 6 |
ENSG00000100739 | BDKRB1 | Bradykinin receptor B1 | [
"P46663"
] | 14 | 96256210-96268967 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002935"
] | [
"B1BKR",
"BKR1",
"bradyb1"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 72: Neuronal - Signal transduction | Cluster 17: Non-specific - RNA processing | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,355 | 2 |
ENSG00000100744 | GSKIP | GSK3B interacting protein | [
"Q9P0R6"
] | 14 | 96363452-96387288 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043054",
"HPA046782"
] | [
"C14orf129"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus",
"Vesicles"
] | [
"Nucleoli"
] | [] | [] | Approved | Approved | null | 10 | No | No | Cluster 5: Non-specific - Cell proliferation | Cluster 14: Neurons - Synaptic function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 42: Retina - Visual perception | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,356 | 3 |
ENSG00000100749 | VRK1 | VRK serine/threonine kinase 1 | [
"Q99986"
] | 14 | 96797304-96954846 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000660",
"HPA017929"
] | [] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell cycle",
"Cell division",
"Host-virus interaction",
"Mitosis"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 58 | Yes | No | Cluster 5: Non-specific - Cell proliferation | Cluster 34: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,357 | 2 |
ENSG00000100764 | PSMC1 | Proteasome 26S subunit, ATPase 1 | [
"P62191"
] | 14 | 90256527-90275429 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000872",
"HPA016885"
] | [
"p56",
"RPT2",
"S4"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Deafness",
"Intellectual disability"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 180 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 21: Non-specific - Metabolism | Cluster 30: Non-specific - Gene expression regulation | Cluster 15: Non-specific - Protein processing | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,358 | 4 |
ENSG00000100784 | RPS6KA5 | Ribosomal protein S6 kinase A5 | [
"O75582"
] | 14 | 90847861-91060641 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001274",
"HPA001780",
"CAB025458"
] | [
"MSK1",
"RLPK"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Inflammatory response",
"Stress response"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 25 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 15: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 2,360 | 8 |
ENSG00000100796 | PPP4R3A | Protein phosphatase 4 regulatory subunit 3A | [
"Q6IN85"
] | 14 | 91457508-91510554 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002568",
"HPA063917"
] | [
"FLFL1",
"FLJ20707",
"KIAA2010",
"MSTP033",
"PP4R3",
"SMEK1",
"smk-1",
"smk1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear speckles",
"Cytosol"
] | [] | [] | Supported | Approved | null | 31 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 55: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 15: Bone marrow - Innate immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 2,361 | 4 |
ENSG00000100802 | C14orf93 | Chromosome 14 open reading frame 93 | [
"Q9H972"
] | 14 | 22985894-23010166 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002569"
] | [
"FLJ12154",
"RTFC"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | Approved | Approved | null | 4 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 46: Brainstem - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 96: Enteroendocrine cells - Neuropeptide signaling | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 2,362 | 4 |
ENSG00000100804 | PSMB5 | Proteasome 20S subunit beta 5 | [
"P28074"
] | 14 | 23016543-23035230 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049518",
"HPA061796"
] | [
"MB1"
] | [
"Enzymes",
"Essential proteins",
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction"
] | [
"Hydrolase",
"Protease",
"Threonine protease"
] | [
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [
"Centrosome",
"Mid piece",
"Principal piece"
] | [] | [] | Supported | Approved | null | 119 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 27: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 97: Non-specific - Cellular respiration | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 6 | 2 | 5 | [
"Colon Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Colon Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 2,363 | 2 |
ENSG00000100811 | YY1 | YY1 transcription factor | [
"P25490"
] | 14 | 100238298-100282788 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000597",
"HPA001119",
"CAB009392"
] | [
"DELTA",
"INO80S",
"NF-E1",
"UCRBP",
"YIN-YANG-1"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"DNA damage",
"DNA recombination",
"DNA repair",
"Spermatogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Nucleoli fibrillar center",
"Nuclear bodies"
] | [] | [] | Supported | Supported | null | 176 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 17: Non-specific - RNA processing | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,364 | 5 |
ENSG00000100813 | ACIN1 | Apoptotic chromatin condensation inducer 1 | [
"Q9UKV3"
] | 14 | 23058564-23095614 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000657"
] | [
"ACINUS",
"fSAP152",
"KIAA0670"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Apoptosis",
"mRNA processing",
"mRNA splicing"
] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Supported | null | 83 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 6: Non-specific - Immune response | Cluster 30: Non-specific - Gene expression regulation | Cluster 17: Non-specific - RNA processing | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,365 | 3 |
ENSG00000100814 | CCNB1IP1 | Cyclin B1 interacting protein 1 | [
"Q9NPC3"
] | 14 | 20311368-20333312 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"C14orf18",
"HEI10"
] | [
"Cancer-related genes",
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Meiosis",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | null | null | 16 | null | null | Cluster 18: Non-specific - Translation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 25: Non-specific - Ribosome | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,366 | 2 |
ENSG00000100815 | TRIP11 | Thyroid hormone receptor interactor 11 | [
"Q15643"
] | 14 | 91965991-92040896 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002570"
] | [
"CEV14",
"GMAP-210",
"GMAP210",
"Trip230"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes",
"Disease variant",
"Dwarfism"
] | [
"Golgi apparatus"
] | [
"Primary cilium"
] | [] | [] | Supported | Supported | null | 20 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 50: Non-specific - Nucleic acid binding | Cluster 30: Non-specific - Gene expression regulation | Cluster 8: Non-specific - Secretory pathway | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 2,367 | 3 |
ENSG00000100836 | PABPN1 | Poly(A) binding protein nuclear 1 | [
"Q86U42"
] | 14 | 23321457-23326163 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000637",
"HPA079093"
] | [
"OPMD",
"PAB2",
"PABP2"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing"
] | [
"RNA-binding"
] | [
"Disease variant"
] | [
"Nucleoplasm",
"Nuclear speckles"
] | [] | [] | [] | Supported | Supported | null | 21 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 30: Non-specific - Gene expression regulation | Cluster 102: Non-specific - Mixed function | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,369 | 1 |
ENSG00000100842 | EFS | Embryonal Fyn-associated substrate | [
"O43281"
] | 14 | 23356403-23365752 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001581",
"HPA001790"
] | [
"CASS3",
"EFS1",
"EFS2",
"HEFS",
"SIN"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Uncertain | Approved | null | 16 | No | null | null | Cluster 11: White matter - Signal transduction | Cluster 12: Bone cancer - Neuronal signaling | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 2,370 | 7 |
ENSG00000100852 | ARHGAP5 | Rho GTPase activating protein 5 | [
"Q13017"
] | 14 | 32076114-32159728 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046993",
"HPA056507"
] | [
"GFI2",
"p190-B",
"p190BRhoGAP",
"RhoGAP5"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 12 | null | null | Cluster 24: Non-specific - Transcription | Cluster 55: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 42: Retina - Visual perception | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 2,371 | 5 |
ENSG00000100865 | CINP | Cyclin dependent kinase 2 interacting protein | [
"Q9BW66"
] | 14 | 102341102-102362916 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"MGC849"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA damage",
"DNA repair",
"DNA replication",
"Ribosome biogenesis"
] | [] | [] | [] | [] | [] | [] | null | null | null | 44 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 28: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe"
] | 2,372 | 2 |
ENSG00000100867 | DHRS2 | Dehydrogenase/reductase 2 | [
"Q13268"
] | 14 | 23630115-23645639 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053915",
"HPA069551"
] | [
"HEP27",
"SDR25C1"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [] | [
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 3 | No | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 27: Breast cancer - Unknown function | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in many | 6 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,373 | 1 |
ENSG00000100883 | SRP54 | Signal recognition particle 54 | [
"P61011"
] | 14 | 34981957-35029686 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048977",
"HPA062044"
] | [] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [] | [
"Hydrolase",
"Ribonucleoprotein",
"RNA-binding"
] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 54 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 21: Non-specific - Metabolism | Cluster 30: Non-specific - Gene expression regulation | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 4 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,374 | 9 |
ENSG00000100888 | CHD8 | Chromodomain helicase DNA binding protein 8 | [
"Q9HCK8"
] | 14 | 21385194-21456126 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052186",
"HPA076133"
] | [
"DUPLIN",
"HELSNF1",
"KIAA1564"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Wnt signaling pathway"
] | [
"Activator",
"Chromatin regulator",
"DNA-binding",
"Hydrolase",
"Repressor"
] | [
"Autism",
"Autism spectrum disorder",
"Cancer-related genes",
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Plasma membrane",
"Primary cilium",
"Primary cilium tip"
] | [] | [] | Supported | null | null | 62 | null | null | Cluster 41: Basophils - Unknown function | Cluster 16: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 7: Non-specific - Transcription | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,376 | 9 |
ENSG00000100889 | PCK2 | Phosphoenolpyruvate carboxykinase 2, mitochondrial | [
"Q16822"
] | 14 | 24094053-24110598 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB018734",
"HPA051162",
"HPA053502"
] | [
"PEPCK",
"PEPCK2"
] | [
"Citric acid cycle related proteins",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Gluconeogenesis"
] | [
"Decarboxylase",
"Lyase"
] | [
"Disease variant"
] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Enhanced | null | 6 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 13: Non-specific - Mixed function | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 26: Kidney & Intestine - Metabolism | Group enriched | Detected in all | 6 | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 2,377 | 6 |
ENSG00000100890 | PRORP | Protein only RNase P catalytic subunit | [
"O15091"
] | 14 | 35121846-35277622 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020459"
] | [
"KIAA0391",
"MRPP3"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [
"Hydrolase",
"Nuclease"
] | [
"Disease variant",
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 2 | null | null | Cluster 39: T-cells - T-cell receptor | Cluster 50: Non-specific - Nucleic acid binding | Cluster 30: Non-specific - Gene expression regulation | Cluster 22: Non-specific - Basic cellular functions | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in some | 5 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,378 | 7 |
ENSG00000100897 | DCAF11 | DDB1 and CUL4 associated factor 11 | [
"Q8TEB1"
] | 14 | 24114195-24125242 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003583",
"HPA031157"
] | [
"GL014",
"PRO2389",
"WDR23"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 38 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 51: Neurons - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 22: Non-specific - Basic cellular functions | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 2,379 | 7 |
ENSG00000100902 | PSMA6 | Proteasome 20S subunit alpha 6 | [
"P60900"
] | 14 | 35278633-35317493 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003049"
] | [
"IOTA",
"MGC22756",
"MGC2333",
"MGC23846",
"p27K",
"PROS27"
] | [
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Primary cilium",
"Primary cilium tip",
"Cytosol",
"Perinuclear theca",
"Calyx",
"Connecting piece",
"Flagellar centriole",
"Mid piece",
"End piece"
] | [] | [] | Supported | Approved | null | 156 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 21: Non-specific - Metabolism | Cluster 30: Non-specific - Gene expression regulation | Cluster 22: Non-specific - Basic cellular functions | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 6 | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,380 | 4 |
ENSG00000100906 | NFKBIA | NFKB inhibitor alpha | [
"P25963"
] | 14 | 35401079-35404749 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB003815",
"HPA029207"
] | [
"IkappaBalpha",
"IKBA",
"MAD-3",
"NFKBI"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Host-virus interaction"
] | [] | [
"Cancer-related genes",
"Disease variant",
"Ectodermal dysplasia"
] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 107 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 12: Non-specific - Vasculature | Cluster 55: Lymphoma - Immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,381 | 2 |
ENSG00000100908 | EMC9 | ER membrane protein complex subunit 9 | [
"Q9Y3B6"
] | 14 | 24138959-24141591 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA078254"
] | [
"C14orf122",
"CGI-112",
"FAM158A"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 145 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 23: Choroid plexus - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 2,382 | 2 |
ENSG00000100911 | PSME2 | Proteasome activator subunit 2 | [
"Q9UL46"
] | 14 | 24143362-24147570 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA062661",
"CAB080614"
] | [
"PA28beta"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 65 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 22: Non-specific - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Breast Invasive Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,383 | 3 |
ENSG00000100916 | BRMS1L | BRMS1 like transcriptional repressor | [
"Q5PSV4"
] | 14 | 35826338-35932325 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046623"
] | [
"BRMS1",
"FLJ39177",
"MGC11296"
] | [
"Predicted intracellular proteins"
] | [
"Growth regulation",
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 44 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 20: Non-specific - Transcription regulation | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,384 | 8 |
ENSG00000100918 | REC8 | REC8 meiotic recombination protein | [
"O95072"
] | 14 | 24171853-24180257 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031727",
"HPA031729"
] | [
"kleisin-alpha",
"REC8L1",
"Rec8p"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Chromosome partition",
"Meiosis"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 15 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 49: Hindbrain - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 64: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 5 | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,385 | 6 |
ENSG00000100934 | SEC23A | SEC23 homolog A, COPII coat complex component | [
"Q15436"
] | 14 | 39031919-39109646 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA069974"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [] | [
"Disease variant"
] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 66 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 23: Choroid plexus - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 8: Non-specific - Secretory pathway | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Skin Cutaneous Melanoma"
] | 2,387 | 5 |
ENSG00000100938 | GMPR2 | Guanosine monophosphate reductase 2 | [
"Q9P2T1"
] | 14 | 24232422-24239242 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000904",
"HPA067884",
"HPA068782"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Purine metabolism"
] | [
"Oxidoreductase"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli"
] | [] | [] | Approved | Approved | null | 6 | No | No | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 45: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,388 | 4 |
ENSG00000100941 | PNN | Pinin, desmosome associated protein | [
"Q9H307"
] | 14 | 39175183-39183220 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001378"
] | [
"memA"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"mRNA processing",
"mRNA splicing",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Tumor suppressor"
] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Supported | null | 107 | null | null | Cluster 24: Non-specific - Transcription | Cluster 6: Non-specific - Immune response | Cluster 30: Non-specific - Gene expression regulation | Cluster 17: Non-specific - RNA processing | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Rectum Adenocarcinoma"
] | [
"Prostate Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Prostate Adenocarcinoma",
"Rectum Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 2,389 | 2 |
ENSG00000100968 | NFATC4 | Nuclear factor of activated T cells 4 | [
"Q14934"
] | 14 | 24365673-24379604 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031641",
"CAB032859",
"HPA076526"
] | [
"NFAT3"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [] | [
"Nuclear speckles",
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 4 | No | No | null | Cluster 44: Non-specific - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 22: Non-specific - Basic cellular functions | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,391 | 7 |
ENSG00000100982 | PCIF1 | Phosphorylated CTD interacting factor 1 | [
"Q9H4Z3"
] | 20 | 45934683-45948023 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049517"
] | [
"bA465L10.1",
"C20orf67",
"CAPAM",
"PPP1R121"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Methyltransferase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Microtubules",
"Cytokinetic bridge"
] | [] | [] | Supported | Enhanced | null | 2 | Yes | No | Cluster 41: Basophils - Unknown function | Cluster 25: Non-specific - Transcription | Cluster 62: Non-specific - Plasma proteins | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Bladder Urothelial Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma"
] | 2,393 | 5 |
ENSG00000100983 | GSS | Glutathione synthetase | [
"P48637"
] | 20 | 34928432-34956027 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054508",
"HPA059315"
] | [] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Glutathione biosynthesis"
] | [
"Ligase"
] | [
"Disease variant",
"FDA approved drug targets",
"Hereditary hemolytic anemia"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 1 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 14: Neurons - Synaptic function | Cluster 62: Non-specific - Plasma proteins | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,394 | 2 |
ENSG00000100985 | MMP9 | Matrix metallopeptidase 9 | [
"P14780"
] | 20 | 46008908-46016561 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000348",
"HPA001238",
"HPA063909",
"CAB068199",
"CAB068200",
"CAB068201"
] | [
"CLG4B"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted secreted proteins"
] | [
"Collagen degradation"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | Approved | Enhanced | null | 9 | null | null | Cluster 4: Neutrophils - Degranulation | Cluster 12: Non-specific - Vasculature | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 15: Bone marrow - Innate immune response | Group enriched | Detected in many | 11 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in some | 6 | Immune cell enriched | Detected in some | 127 | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,395 | 7 |
ENSG00000100987 | VSX1 | Visual system homeobox 1 | [
"Q9NZR4"
] | 20 | 25070885-25082141 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA079607"
] | [
"PPCD",
"PPCD1",
"PPD"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Sensory transduction",
"Transcription",
"Transcription regulation",
"Vision"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Corneal dystrophy",
"Disease variant"
] | [
"Nucleoli"
] | [] | [] | [] | Approved | null | null | 2 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in some | 8 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 16 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 2,396 | 7 |
ENSG00000100991 | TRPC4AP | Transient receptor potential cation channel subfamily C member 4 associated protein | [
"Q8TEL6"
] | 20 | 35002404-35092807 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051197",
"HPA065061"
] | [
"C20orf188",
"dJ756N5.2",
"DKFZp586C1223",
"DKFZP727M231",
"PPP1R158",
"TRRP4AP"
] | [
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Ubl conjugation pathway"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 16 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 28: Oligodendrocytes - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 2,397 | 5 |
ENSG00000100994 | PYGB | Glycogen phosphorylase B | [
"P11216"
] | 20 | 25248085-25298012 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031067"
] | [] | [
"Candidate cardiovascular disease genes",
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism",
"Glycogen metabolism"
] | [
"Allosteric enzyme",
"Glycosyltransferase",
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 27 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 45: Non-specific - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,398 | 7 |
ENSG00000100997 | ABHD12 | Abhydrolase domain containing 12, lysophospholipase | [
"Q8N2K0"
] | 20 | 25294742-25390835 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026866"
] | [
"ABHD12A",
"BEM46L2",
"C20orf22",
"dJ965G21.2",
"DKFZP434P106"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Lipid metabolism"
] | [
"Hydrolase"
] | [
"Cataract",
"Deafness",
"Disease variant",
"Neuropathy",
"Retinitis pigmentosa"
] | [] | [] | [] | [] | null | Uncertain | null | 10 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func. | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,399 | 1 |
ENSG00000101003 | GINS1 | GINS complex subunit 1 | [
"Q14691"
] | 20 | 25391008-25452700 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051185"
] | [
"KIAA0186",
"PSF1"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"DNA replication"
] | [] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 19 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 62: Non-specific - Plasma proteins | Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 5 | 2 | 4 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 2,401 | 9 |
ENSG00000101004 | NINL | Ninein like | [
"Q9Y2I6"
] | 20 | 25451594-25585531 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000686"
] | [
"KIAA0980",
"NLP"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles",
"Primary cilium"
] | [
"Nucleoplasm",
"Microtubules",
"Cytokinetic bridge",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 99 | Yes | No | null | Cluster 44: Non-specific - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 2,402 | 5 |
ENSG00000101017 | CD40 | CD40 molecule | [
"P25942"
] | 20 | 46118271-46129863 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002495",
"HPA031567",
"HPA031568",
"CAB072868",
"CAB080468"
] | [
"Bp50",
"p50",
"TNFRSF5"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Immunity"
] | [
"Receptor"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Vesicles"
] | [
"Plasma membrane"
] | [
"Secreted to blood"
] | [
"Receptor"
] | Approved | Enhanced | null | 76 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 42: Choroid plexus - Mitochondria | Cluster 55: Lymphoma - Immune response | Cluster 82: Dendritic cells - Antigen presentation | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 2,403 | 6 |
ENSG00000101019 | UQCC1 | Ubiquinol-cytochrome c reductase complex assembly factor 1 | [
"Q9NVA1"
] | 20 | 35302566-35412031 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034875"
] | [
"BFZB",
"C20orf44",
"CBP3",
"FLJ10850",
"UQCC"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [
"Nucleoplasm",
"Actin filaments"
] | [] | [] | Approved | Approved | null | 27 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 62: Non-specific - Plasma proteins | Cluster 55: Myocytes - Oxidative muscle function | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,404 | 1 |
ENSG00000101040 | ZMYND8 | Zinc finger MYND-type containing 8 | [
"Q9ULU4"
] | 20 | 47209214-47356889 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020949",
"HPA051579"
] | [
"KIAA1125",
"PRKCBP1",
"RACK7"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator"
] | [
"Disease variant",
"Tumor suppressor"
] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 46 | null | null | Cluster 32: Basophils - Transcription | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 5: Rhabdoid - Unknown function | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,405 | 6 |
ENSG00000101049 | SGK2 | Serum/glucocorticoid regulated kinase 2 | [
"Q9HBY8"
] | 20 | 43558968-43588237 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008859",
"HPA011387"
] | [] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 6 | null | null | null | Cluster 30: White matter - Myelination | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 26: Kidney & Intestine - Metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,406 | 2 |
ENSG00000101052 | IFT52 | Intraflagellar transport 52 | [
"Q9Y366"
] | 20 | 43590937-43647299 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA063367",
"HPA067423"
] | [
"C20orf9",
"CGI-53",
"dJ1028D15.1",
"NGD2",
"NGD5"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [
"Ciliopathy",
"Disease variant"
] | [
"Microtubules"
] | [
"Primary cilium",
"Basal body",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 37 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 62: Non-specific - Plasma proteins | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,407 | 3 |
ENSG00000101057 | MYBL2 | MYB proto-oncogene like 2 | [
"P10244"
] | 20 | 43667019-43716495 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017114",
"HPA030530",
"HPA055416"
] | [
"B-MYB",
"BMYB"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 35 | Yes | Yes | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | null | Cluster 62: Non-specific - Plasma proteins | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | Cluster 44: Bone marrow - Nuclear processes | Group enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Cancer enriched | Detected in all | 5 | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 34 | 5 | 6 | 2 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,408 | 4 |
ENSG00000101074 | R3HDML | R3H domain containing like | [
"Q9H3Y0"
] | 20 | 44337043-44351238 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | [
"HPA062414",
"HPA070264"
] | [
"dJ881L22.3"
] | [
"Predicted secreted proteins"
] | [] | [
"Protease inhibitor"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [
"Secreted - unknown location"
] | [
"Enzyme inhibitor"
] | Approved | Enhanced | null | 1 | null | null | null | Cluster 34: Non-specific - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 7: Small intestine - Absorption and Digestion | Tissue enriched | Detected in single | 5 | Cancer enriched | Detected in some | 4 | Group enriched | Detected in some | 6 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,409 | 2 |
ENSG00000101076 | HNF4A | Hepatocyte nuclear factor 4 alpha | [
"P41235"
] | 20 | 44355699-44432845 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004712",
"CAB019417"
] | [
"HNF4",
"MODY",
"MODY1",
"NR2A1",
"TCF14"
] | [
"Disease related genes",
"Human disease related genes",
"Nuclear receptors",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Receptor",
"Repressor"
] | [
"Diabetes mellitus",
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 38 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 77: Intestine - Digestion | Group enriched | Detected in some | 4 | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,410 | 1 |
ENSG00000101082 | SLA2 | Src like adaptor 2 | [
"Q9H6Q3"
] | 20 | 36612318-36646196 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA053746",
"HPA058217"
] | [
"C20orf156",
"FLJ21992",
"SLAP-2"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Golgi apparatus",
"Vesicles"
] | [] | [] | [] | Approved | null | null | 6 | No | null | Cluster 3: Non-specific - Nuclear processes | Cluster 48: Non-specific - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in some | 9 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 6 | 1 | 0 | 1 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 2,412 | 5 |
ENSG00000101084 | RAB5IF | RAB5 interacting factor | [
"Q9BUV8"
] | 20 | 36605779-36612557 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA057387",
"HPA076106"
] | [
"C20orf24",
"PNAS-11",
"RCAF1",
"RIP5"
] | [
"Disease related genes",
"Predicted membrane proteins"
] | [] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Uncertain | null | 10 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 7: Liver cancer - Metabolism | Cluster 84: Apical squamous epithelium - Cornification | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 2,413 | 7 |
ENSG00000101096 | NFATC2 | Nuclear factor of activated T cells 2 | [
"Q13469"
] | 20 | 51386957-51562831 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008789",
"CAB018567",
"HPA024369"
] | [
"NF-ATP",
"NFAT1",
"NFATp"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 22 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 3: Choroid plexus - Cilium | Cluster 69: Skin cancer - ECM organization | Cluster 103: Non-specific - Basic cellular processes | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 2,414 | 1 |
ENSG00000101098 | RIMS4 | Regulating synaptic membrane exocytosis 4 | [
"Q9H426"
] | 20 | 44751808-44810546 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA060928"
] | [
"C20orf190",
"dJ781B1.3"
] | [
"Predicted intracellular proteins"
] | [
"Exocytosis",
"Neurotransmitter transport",
"Transport"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,415 | 3 |
ENSG00000101104 | PABPC1L | Poly(A) binding protein cytoplasmic 1 like | [
"Q4VXU2"
] | 20 | 44910060-44959035 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA066650"
] | [
"C20orf119",
"dJ1069P2.3",
"ePAB",
"PABPC1L1"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Oogenesis"
] | [
"RNA-binding"
] | [
"Disease variant"
] | [
"Cytosol"
] | [
"Nuclear bodies"
] | [] | [] | Approved | null | null | 1 | null | Yes | null | Cluster 17: Choroid plexus - Cilium | Cluster 56: Non-specific - Sensory perception | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Prostate Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Prostate Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 2,416 | 7 |
ENSG00000101115 | SALL4 | Spalt like transcription factor 4 | [
"Q9UJQ4"
] | 20 | 51782331-51802521 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015291",
"HPA015791"
] | [
"dJ1112F19.1",
"ZNF797"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [
"Cancer-related genes",
"Deafness",
"Disease variant",
"Oncogene"
] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Supported | Enhanced | null | 9 | Yes | No | null | Cluster 55: Non-specific - Transcription | Cluster 34: Testis cancer - Unknown function | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 21: Testis - Mixed function | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 14 | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 9 | 0 | 0 | 0 | [] | [] | [] | 2,418 | 8 |
ENSG00000101126 | ADNP | Activity dependent neuroprotector homeobox | [
"Q9H2P0"
] | 20 | 50888916-50931437 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006371",
"HPA050560"
] | [
"ADNP1",
"KIAA0784"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [
"Autism spectrum disorder",
"Cancer-related genes",
"Intellectual disability"
] | [
"Nucleoplasm",
"Centrosome"
] | [
"Primary cilium",
"Primary cilium tip",
"Basal body"
] | [] | [] | Approved | Supported | null | 42 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 31: Non-specific - Transcription | Cluster 62: Non-specific - Plasma proteins | Cluster 7: Non-specific - Transcription | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,419 | 1 |
ENSG00000101132 | PFDN4 | Prefoldin subunit 4 | [
"Q9NQP4"
] | 20 | 54208087-54228052 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA024055"
] | [
"C-1",
"C1",
"PFD4"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Chaperone"
] | [] | [] | [] | [] | [] | null | Approved | null | 45 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 1: Neurons - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 97: Non-specific - Cellular respiration | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,420 | 8 |
ENSG00000101134 | DOK5 | Docking protein 5 | [
"Q9P104"
] | 20 | 54475593-54651169 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054460",
"HPA065235"
] | [
"C20orf180",
"dJ805C22.1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Focal adhesion sites"
] | [] | [] | [] | Approved | Uncertain | null | 1 | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 64: Connective tissue cells - ECM organization | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 62: Skeletal muscle - Muscle contraction | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,421 | 6 |
ENSG00000101138 | CSTF1 | Cleavage stimulation factor subunit 1 | [
"Q05048"
] | 20 | 56392371-56406362 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB019270",
"HPA047275",
"HPA065000"
] | [] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 22 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 55: Non-specific - Transcription | Cluster 62: Non-specific - Plasma proteins | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,422 | 2 |
ENSG00000101144 | BMP7 | Bone morphogenetic protein 7 | [
"P18075"
] | 20 | 57168753-57266641 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA061339"
] | [
"OP-1"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Chondrogenesis",
"Differentiation",
"Osteogenesis"
] | [
"Cytokine",
"Developmental protein",
"Growth factor"
] | [] | [
"Vesicles"
] | [
"Nucleoplasm"
] | [
"Secreted to blood"
] | [
"Cytokine"
] | Approved | null | null | 23 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 33: Thyroid gland - Tissue development | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,423 | 5 |
ENSG00000101150 | TPD52L2 | TPD52 like 2 | [
"O43399"
] | 20 | 63865228-63891545 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047489"
] | [
"D54",
"hD54",
"TPD54"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 21 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 27: Non-specific - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 102: Non-specific - Mixed function | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Thyroid Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Thyroid Carcinoma"
] | 2,425 | 3 |
ENSG00000101152 | DNAJC5 | DnaJ heat shock protein family (Hsp40) member C5 | [
"Q9H3Z4"
] | 20 | 63895126-63936031 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012737",
"HPA012781",
"HPA013154"
] | [
"CLN4",
"DNAJC5A",
"FLJ00118",
"FLJ13070"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [
"Chaperone"
] | [
"Disease variant",
"Neurodegeneration",
"Neuronal ceroid lipofuscinosis"
] | [
"Vesicles"
] | [
"Golgi apparatus",
"Perinuclear theca",
"Principal piece",
"End piece"
] | [] | [] | Supported | Approved | null | 34 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 1: Neurons - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 102: Non-specific - Mixed function | Cluster 10: Brain - Synaptic signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,426 | 6 |
ENSG00000101158 | NELFCD | Negative elongation factor complex member C/D | [
"Q8IXH7"
] | 20 | 58981208-58995133 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050641",
"HPA066262",
"HPA074936"
] | [
"HSPC130",
"NELF-C",
"NELF-D",
"TH1",
"TH1L"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Repressor",
"RNA-binding"
] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 22 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,427 | 5 |
ENSG00000101160 | CTSZ | Cathepsin Z | [
"Q9UBR2"
] | 20 | 58985686-59008238 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025114",
"HPA049876",
"HPA053504"
] | [
"CTSX"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Vesicles"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Supported | Supported | null | 17 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 21: Non-specific - Metabolism | Cluster 15: Kidney cancer - Membrane components | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 28: Liver & Adrenal gland - Secretion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 2,428 | 3 |
ENSG00000101161 | PRPF6 | Pre-mRNA processing factor 6 | [
"O94906"
] | 20 | 63981132-64033100 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047106"
] | [
"ANT-1",
"bB152O15.1",
"C20orf14",
"hPrp6",
"Prp6",
"RP60",
"SNRNP102",
"TOM",
"U5-102K"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [
"Disease variant",
"Retinitis pigmentosa"
] | [
"Nucleoplasm",
"Nuclear speckles",
"Basal body"
] | [
"Vesicles",
"Centrosome",
"Cytosol"
] | [] | [] | Supported | Supported | null | 142 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 55: Non-specific - Transcription | Cluster 62: Non-specific - Plasma proteins | Cluster 17: Non-specific - RNA processing | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,429 | 8 |
ENSG00000101162 | TUBB1 | Tubulin beta 1 class VI | [
"Q9H4B7"
] | 20 | 59019429-59026654 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004286",
"HPA043640",
"HPA046280"
] | [
"dJ543J19.4"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [] | [] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Microtubules"
] | [
"Cytokinetic bridge",
"Mitotic spindle",
"Primary cilium",
"Primary cilium tip",
"Basal body",
"Flagellar centriole",
"Principal piece",
"End piece"
] | [] | [] | Supported | Approved | null | 19 | Yes | null | Cluster 21: Neutrophils - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 47: Leukemia - Hemostasis | Cluster 47: Platelets - Hemostasis | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 9 | Group enriched | Detected in many | 17 | 0 | 0 | 0 | [] | [] | [] | 2,430 | 1 |
ENSG00000101166 | PRELID3B | PRELI domain containing 3B | [
"Q9Y3B1"
] | 20 | 59033145-59042809 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047721"
] | [
"C20orf45",
"dJ543J19.5",
"SLMO2"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 4 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 21: Non-specific - Metabolism | Cluster 62: Non-specific - Plasma proteins | Cluster 84: Apical squamous epithelium - Cornification | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Rectum Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Rectum Adenocarcinoma"
] | 2,431 | 5 |
ENSG00000101180 | HRH3 | Histamine receptor H3 | [
"Q9Y5N1"
] | 20 | 62214960-62220278 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"GPCR97"
] | [
"FDA approved drug targets",
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | null | null | 1 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 109: Neurons - Neuronal signaling | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in some | 28 | Group enriched | Detected in some | 5 | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,432 | 9 |
ENSG00000101181 | MTG2 | Mitochondrial ribosome associated GTPase 2 | [
"Q9H4K7"
] | 20 | 62183028-62203568 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047379"
] | [
"dJ1005F21.2",
"FLJ10741",
"GTPBP5",
"ObgH1"
] | [
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis",
"Translation regulation"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 48 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 25: Non-specific - Transcription | Cluster 62: Non-specific - Plasma proteins | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Prostate Adenocarcinoma"
] | [
"Prostate Adenocarcinoma"
] | 2,433 | 5 |
ENSG00000101182 | PSMA7 | Proteasome 20S subunit alpha 7 | [
"O14818"
] | 20 | 62136733-62143440 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB046007",
"CAB046008",
"HPA047266",
"HPA071263"
] | [
"C6",
"HSPC",
"RC6-1",
"XAPC7"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction"
] | [] | [] | [
"Vesicles",
"Principal piece"
] | [] | [] | [] | Uncertain | Approved | null | 160 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,434 | 6 |
ENSG00000101187 | SLCO4A1 | Solute carrier organic anion transporter family member 4A1 | [
"Q96BD0"
] | 20 | 62642503-62685785 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030669",
"HPA030670"
] | [
"OATP-E",
"OATP4A1",
"SLC21A12"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [] | [] | [
"Cell Junctions"
] | [] | [] | [] | Supported | Uncertain | null | 2 | null | null | Cluster 16: Non-specific - Cell proliferation | Cluster 47: Endothelial cells - Vasculature | Cluster 15: Kidney cancer - Membrane components | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 3 | 0 | 3 | [
"Stomach Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 2,435 | 5 |
ENSG00000101188 | NTSR1 | Neurotensin receptor 1 | [
"P30989"
] | 20 | 62708836-62762771 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050299"
] | [
"NTR"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [
"Plasma membrane"
] | [] | [] | [] | Supported | null | null | 22 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 77: Intestine - Digestion | Tissue enriched | Detected in some | 7 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,436 | 3 |
ENSG00000101189 | MRGBP | MRG domain binding protein | [
"Q9NV56"
] | 20 | 62796473-62801729 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017012"
] | [
"C20orf20",
"Eaf7",
"FLJ10914",
"MRG15BP"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Growth regulation",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Chromatin regulator"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 63 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 37: Neurons - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 67: Testis - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in some | null | 3 | 0 | 3 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,437 | 1 |
ENSG00000101190 | TCFL5 | Transcription factor like 5 | [
"Q9UL49"
] | 20 | 62841005-62861822 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA055223",
"HPA076419"
] | [
"bHLHe82",
"CHA",
"E2BP-1",
"Figlb"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Spermatogenesis",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 1 | null | null | Cluster 19: Eosinophils - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Thyroid Carcinoma"
] | [
"Kidney Chromophobe",
"Thyroid Carcinoma"
] | 2,438 | 2 |
ENSG00000101191 | DIDO1 | Death inducer-obliterator 1 | [
"Q9BTC0"
] | 20 | 62877738-62937952 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004374",
"HPA049904"
] | [
"BYE1",
"C20orf158",
"DATF1",
"DIO-1",
"DIO1",
"dJ885L7.8",
"FLJ11265",
"KIAA0333"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Nucleoplasm"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Approved | Supported | null | 42 | No | No | Cluster 5: Non-specific - Cell proliferation | Cluster 6: Non-specific - Immune response | Cluster 62: Non-specific - Plasma proteins | Cluster 7: Non-specific - Transcription | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Bladder Urothelial Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma"
] | 2,439 | 7 |
ENSG00000101193 | GID8 | GID complex subunit 8 homolog | [
"Q9NWU2"
] | 20 | 62938147-62948475 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049929",
"HPA055047"
] | [
"bA305P22.1",
"C20orf11",
"FLJ20602",
"TWA1"
] | [
"Predicted intracellular proteins"
] | [
"Wnt signaling pathway"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cell Junctions"
] | [] | [] | Supported | Approved | null | 83 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 62: Non-specific - Plasma proteins | Cluster 84: Apical squamous epithelium - Cornification | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,440 | 9 |
ENSG00000101194 | SLC17A9 | Solute carrier family 17 member 9 | [
"Q9BYT1"
] | 20 | 62952707-62969585 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047470"
] | [
"C20orf59",
"FLJ23412",
"VNUT"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | null | 6 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 2,441 | 7 |
ENSG00000101197 | BIRC7 | Baculoviral IAP repeat containing 7 | [
"Q96CA5"
] | 20 | 63235883-63240495 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047850",
"HPA061283"
] | [
"KIAP",
"ML-IAP",
"mliap",
"RNF50"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Ubl conjugation pathway"
] | [
"Protease inhibitor",
"Thiol protease inhibitor",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Centrosome",
"Cytosol"
] | [] | [] | Enhanced | null | null | 45 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 39: Astrocytes - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in many | 5 | Cancer enriched | Detected in many | 8 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 2,442 | 1 |
ENSG00000101198 | NKAIN4 | Sodium/potassium transporting ATPase interacting 4 | [
"Q8IVV8"
] | 20 | 63240784-63272694 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA029876"
] | [
"bA261N11.2",
"C20orf58",
"FAM77A"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 78: Brain - Neuronal signaling | Group enriched | Detected in some | 24 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 7 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 2,443 | 9 |
ENSG00000101199 | ARFGAP1 | ADP ribosylation factor GTPase activating protein 1 | [
"Q8N6T3"
] | 20 | 63272785-63289790 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051019",
"HPA056273"
] | [
"ARF1GAP",
"bA261N11.3",
"FLJ10767"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [
"GTPase activation"
] | [] | [
"Golgi apparatus"
] | [
"Nuclear membrane",
"Vesicles",
"Primary cilium",
"Cytosol"
] | [] | [] | Approved | Approved | null | 16 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 32: Cerebral cortex - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 5 | [
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 2,444 | 6 |
ENSG00000101200 | AVP | Arginine vasopressin | [
"P01185"
] | 20 | 3082556-3084724 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025318",
"HPA071892"
] | [
"ADH",
"ARVP"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted secreted proteins"
] | [
"Host-virus interaction"
] | [
"Hormone",
"Vasoactive",
"Vasoconstrictor"
] | [
"Diabetes insipidus",
"Disease variant"
] | [] | [] | [
"Secreted to blood"
] | [
"Hormone"
] | null | Enhanced | Supported | 2 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 47: Leukemia - Hemostasis | Cluster 109: Neurons - Neuronal signaling | Cluster 36: Brain & Liver - Signaling | Tissue enriched | Detected in some | 747 | Cancer enriched | Detected in single | 108 | Not detected | Not detected | null | Group enriched | Detected in some | 5 | Immune cell enriched | Detected in single | 6 | 0 | 0 | 0 | [] | [] | [] | 2,445 | 1 |
ENSG00000101203 | COL20A1 | Collagen type XX alpha 1 chain | [
"Q9P218"
] | 20 | 63293186-63334851 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA060109"
] | [
"KIAA1510"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Golgi apparatus",
"Vesicles"
] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | Approved | null | null | 1 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 78: Brain - Neuronal signaling | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in single | null | Cancer enriched | Detected in some | 21 | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,446 | 5 |
ENSG00000101204 | CHRNA4 | Cholinergic receptor nicotinic alpha 4 subunit | [
"P43681"
] | 20 | 63343223-63378401 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB034064",
"HPA046054"
] | [
"BFNC",
"EBN",
"EBN1"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"Disease variant",
"Epilepsy",
"FDA approved drug targets"
] | [
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | 5 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | Cluster 31: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 6 | Cancer enhanced | Detected in single | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 2,447 | 8 |
ENSG00000101210 | EEF1A2 | Eukaryotic translation elongation factor 1 alpha 2 | [
"Q05639"
] | 20 | 63488013-63499239 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB034019",
"HPA051759",
"HPA053862",
"HPA056990"
] | [
"EEF1AL",
"HS1",
"STN",
"STNL"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Elongation factor",
"Hydrolase"
] | [
"Autism spectrum disorder",
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 60 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 27: Breast cancer - Unknown function | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Colon Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Colon Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 2,448 | 5 |
ENSG00000101213 | PTK6 | Protein tyrosine kinase 6 | [
"Q13882"
] | 20 | 63528001-63537376 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB032952",
"HPA036070",
"HPA036071"
] | [
"BRK"
] | [
"Cancer-related genes",
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Plasma membrane",
"Cytosol"
] | [] | [] | Supported | Approved | null | 41 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in many | 4 | Immune cell enhanced | Detected in single | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,449 | 7 |
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