ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000101216 | GMEB2 | Glucocorticoid modulatory element binding protein 2 | [
"Q9UKD1"
] | 20 | 63587602-63627101 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA009706",
"HPA067455"
] | [
"KIAA1269",
"P79PIF",
"PIF79"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | Approved | null | 19 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 62: Non-specific - Plasma proteins | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 2,450 | 9 |
ENSG00000101220 | C20orf27 | Chromosome 20 open reading frame 27 | [
"Q9GZN8"
] | 20 | 3753508-3767781 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047483"
] | [
"FLJ20550"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [
"Secreted in other tissues"
] | [
"No annotated function"
] | Approved | Approved | null | 6 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 33: Neurons - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 5 | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,451 | 3 |
ENSG00000101222 | SPEF1 | Sperm flagellar 1 | [
"Q9Y4P9"
] | 20 | 3777504-3781448 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050786"
] | [
"C20orf28",
"CLAMP",
"DKFZP434I114",
"SPEF1A"
] | [
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [
"Actin-binding"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 4 | null | null | null | Cluster 17: Choroid plexus - Cilium | Cluster 10: Ciliated cells - Ion channel activity | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 1: Choroid plexus - Transmembrane transport | Group enriched | Detected in some | 6 | Not detected | Not detected | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 2,452 | 3 |
ENSG00000101224 | CDC25B | Cell division cycle 25B | [
"P30305"
] | 20 | 3786772-3806121 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038892",
"HPA038893",
"HPA075215"
] | [] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [
"Hydrolase",
"Protein phosphatase"
] | [
"Cancer-related genes"
] | [
"Vesicles"
] | [
"Mitotic spindle"
] | [] | [] | Uncertain | Enhanced | null | 34 | Yes | Yes | Cluster 5: Non-specific - Cell proliferation | Cluster 15: Non-specific - Transcription | Cluster 62: Non-specific - Plasma proteins | Cluster 27: Non-specific - Cell proliferation | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,453 | 8 |
ENSG00000101230 | ISM1 | Isthmin 1 | [
"B1AKI9"
] | 20 | 13221274-13300651 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [] | [
"bA149I18.1",
"C20orf82"
] | [
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted in other tissues"
] | [
"No annotated function"
] | null | null | null | null | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 70: DU4475 - Unknown function | Cluster 108: Fibroblasts - ECM organization | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 3 | 0 | 3 | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 2,454 | 4 |
ENSG00000101236 | RNF24 | Ring finger protein 24 | [
"Q9Y225"
] | 20 | 3927309-4015558 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011900"
] | [
"G1L"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | Approved | null | 2 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,455 | 8 |
ENSG00000101246 | ARFRP1 | ADP ribosylation factor related protein 1 | [
"Q13795"
] | 20 | 63698642-63708025 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047028",
"HPA050634"
] | [
"ARL18",
"ARP",
"Arp1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | Approved | null | 4 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 27: Non-specific - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 97: Non-specific - Cellular respiration | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,456 | 4 |
ENSG00000101247 | NDUFAF5 | NADH:ubiquinone oxidoreductase complex assembly factor 5 | [
"Q5TEU4"
] | 20 | 13785007-13821580 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051184"
] | [
"C20orf7",
"dJ842G6.1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Methyltransferase",
"Oxidoreductase",
"Transferase"
] | [
"Disease variant",
"Leigh syndrome",
"Primary mitochondrial disease"
] | [] | [] | [] | [] | null | Uncertain | null | 10 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 55: Myocytes - Oxidative muscle function | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,457 | 2 |
ENSG00000101265 | RASSF2 | Ras association domain family member 2 | [
"P50749"
] | 20 | 4780023-4823608 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051200"
] | [
"CENP-34",
"KIAA0168"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [] | [
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [
"Golgi apparatus",
"Plasma membrane",
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 39 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 30: White matter - Myelination | Cluster 55: Lymphoma - Immune response | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in all | 5 | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,460 | 9 |
ENSG00000101276 | SLC52A3 | Solute carrier family 52 member 3 | [
"Q9NQ40"
] | 20 | 760080-776015 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049391",
"HPA059078"
] | [
"bA371L19.1",
"C20orf54",
"hRFT2",
"RFVT3"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [
"Deafness",
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | null | Cluster 47: Endothelial cells - Vasculature | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 21: Testis - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 4 | 0 | 4 | [
"Stomach Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 2,462 | 4 |
ENSG00000101280 | ANGPT4 | Angiopoietin 4 | [
"Q9Y264"
] | 20 | 869900-916334 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013260",
"CAB013305"
] | [] | [
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [
"Angiogenesis"
] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"Developmental protein"
] | null | Uncertain | null | null | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 34: Testis cancer - Unknown function | Cluster 110: Mural cells - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Not detected | Not detected | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Bladder Urothelial Carcinoma"
] | [
"Bladder Urothelial Carcinoma"
] | 2,463 | 1 |
ENSG00000101290 | CDS2 | CDP-diacylglycerol synthase 2 | [
"O95674"
] | 20 | 5126879-5197887 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019698"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Lipid biosynthesis",
"Lipid metabolism",
"Phospholipid biosynthesis",
"Phospholipid metabolism"
] | [
"Nucleotidyltransferase",
"Transferase"
] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Approved | null | 68 | No | No | Cluster 35: Neutrophils - Protein binding | Cluster 1: Neurons - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 46: Brain & retina - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,465 | 2 |
ENSG00000101292 | PROKR2 | Prokineticin receptor 2 | [
"Q8NFJ6"
] | 20 | 5299218-5316954 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047281"
] | [
"dJ680N4.3",
"GPR73b",
"GPR73L1",
"GPRg2",
"KAL3",
"PKR2"
] | [
"Disease related genes",
"G-protein coupled receptors",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"Disease variant",
"Hypogonadotropic hypogonadism",
"Kallmann syndrome"
] | [] | [] | [] | [] | null | Uncertain | null | 5 | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 27: Breast cancer - Unknown function | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in single | null | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in some | 6 | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 2,466 | 4 |
ENSG00000101294 | HM13 | Histocompatibility minor 13 | [
"Q8TCT9"
] | 20 | 31514410-31577923 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045089",
"HPA056062"
] | [
"dJ324O17.1",
"H13",
"IMP1",
"IMPAS",
"PSENL3",
"PSL3",
"SPP",
"SPPL1"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Hydrolase",
"Protease"
] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Enhanced | null | 12 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 15: Kidney cancer - Membrane components | Cluster 8: Non-specific - Secretory pathway | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 4 | 1 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,467 | 8 |
ENSG00000101298 | SNPH | Syntaphilin | [
"O15079"
] | 20 | 1266280-1309328 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049393"
] | [
"bA314N13.5"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [
"Cytokinetic bridge"
] | [] | [] | Uncertain | Approved | null | 5 | Yes | No | Cluster 43: Non-specific - Transcription & Translation | Cluster 32: Cerebral cortex - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 109: Neurons - Neuronal signaling | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in many | 6 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,468 | 1 |
ENSG00000101306 | MYLK2 | Myosin light chain kinase 2 | [
"Q9H1R3"
] | 20 | 31819308-31834689 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA059704",
"HPA059890"
] | [
"KMLC",
"MLCK2",
"skMLCK"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Calmodulin-binding",
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Cardiomyopathy",
"Disease variant"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Enhanced | null | 14 | null | null | null | null | Cluster 38: Non-specific - Transcription | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enriched | Detected in some | 12 | Low cancer specificity | Detected in some | null | Cancer enhanced | Detected in single | null | Cell type enriched | Detected in some | 14 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,469 | 2 |
ENSG00000101307 | SIRPB1 | Signal regulatory protein beta 1 | [
"O00241",
"Q5TFQ8"
] | 20 | 1561385-1620061 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047463"
] | [
"CD172b",
"SIRP-BETA-1"
] | [
"CD markers",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Vesicles"
] | [
"Centrosome"
] | [] | [] | Uncertain | Uncertain | null | 4 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 34: Non-specific - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 2,470 | 8 |
ENSG00000101310 | SEC23B | SEC23 homolog B, COPII coat complex component | [
"Q15437"
] | 20 | 18507520-18561415 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008216",
"HPA069974"
] | [
"CDA-II",
"CDAII",
"CDAN2",
"HEMPAS"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [] | [
"Congenital dyserythropoietic anemia",
"Disease variant",
"Hereditary hemolytic anemia"
] | [
"Endoplasmic reticulum",
"Vesicles",
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 43 | null | Yes | Cluster 10: Non-specific - Membrane trafficking | Cluster 28: Oligodendrocytes - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 8: Pancreas - Proteolysis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Lung Squamous Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | 2,471 | 6 |
ENSG00000101311 | FERMT1 | FERM domain containing kindlin 1 | [
"Q9BQL6"
] | 20 | 6074845-6123214 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039778",
"HPA041966"
] | [
"C20orf42",
"FLJ20116",
"KIND1",
"UNC112A",
"URP1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell adhesion"
] | [] | [
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 49: Hindbrain - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 2,472 | 2 |
ENSG00000101323 | HAO1 | Hydroxyacid oxidase 1 | [
"Q9UJM8"
] | 20 | 7882985-7940458 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049552",
"HPA072442"
] | [
"GOX",
"GOX1"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Amino-acid biosynthesis"
] | [
"Oxidoreductase"
] | [
"FDA approved drug targets"
] | [
"Vesicles"
] | [] | [] | [] | Supported | Enhanced | null | null | null | null | null | null | Cluster 7: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in single | 584 | Not detected | Not detected | null | Cancer enriched | Detected in single | 179 | Cell type enriched | Detected in some | 34 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,473 | 8 |
ENSG00000101327 | PDYN | Prodynorphin | [
"P01213"
] | 20 | 1978757-1994285 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053342",
"CAB079777"
] | [
"ADCA",
"PENKB",
"SCA23"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted secreted proteins",
"Transporters"
] | [] | [
"Endorphin",
"Neuropeptide",
"Neurotransmitter",
"Opioid peptide"
] | [
"Disease variant",
"Neurodegeneration",
"Spinocerebellar ataxia"
] | [] | [] | [
"Secreted in brain"
] | [
"Neuropeptide"
] | null | Enhanced | Supported | 4 | null | null | null | Cluster 29: Forebrain - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in some | 12 | Cancer enriched | Detected in single | 12 | Group enriched | Detected in some | 20 | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,474 | 3 |
ENSG00000101331 | CCM2L | CCM2 like scaffold protein | [
"Q9NUG4"
] | 20 | 32010438-32032180 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008434",
"HPA071063"
] | [
"C20orf160",
"dJ310O13.5"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 3 | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 5: Spleen - Immune response | Tissue enriched | Detected in many | 6 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,475 | 7 |
ENSG00000101333 | PLCB4 | Phospholipase C beta 4 | [
"Q15147"
] | 20 | 9067825-9504593 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA007951"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Lipid degradation",
"Lipid metabolism"
] | [
"Hydrolase",
"Transducer"
] | [
"Disease variant"
] | [
"Plasma membrane",
"Microtubules",
"Primary cilium",
"Basal body"
] | [
"Nucleoplasm",
"Actin filaments",
"Cytokinetic bridge",
"Centrosome",
"Acrosome",
"Equatorial segment",
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | Uncertain | Approved | null | 1 | Yes | null | Cluster 2: Dendritic cells - Unknown function | Cluster 25: Non-specific - Transcription | Cluster 15: Kidney cancer - Membrane components | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 4 | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Lung Squamous Cell Carcinoma"
] | 2,476 | 2 |
ENSG00000101335 | MYL9 | Myosin light chain 9 | [
"P24844"
] | 20 | 36541497-36551447 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039262",
"HPA045244",
"HPA059197"
] | [
"LC20",
"MLC2",
"MRLC1",
"MYRL2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Motor protein",
"Muscle protein",
"Myosin"
] | [] | [] | [] | [] | [] | null | Supported | null | 17 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 64: Connective tissue cells - ECM organization | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 2,477 | 4 |
ENSG00000101336 | HCK | HCK proto-oncogene, Src family tyrosine kinase | [
"P08631"
] | 20 | 32052197-32101856 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005195",
"HPA035534",
"HPA063768"
] | [
"JTK9"
] | [
"Disease related genes",
"Enzymes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Exocytosis",
"Host-virus interaction",
"Immunity",
"Inflammatory response",
"Innate immunity",
"Phagocytosis"
] | [
"Kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Proto-oncogene"
] | [
"Vesicles"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | Supported | Approved | null | 47 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 20: Macrophages & Microglia - Immune response | Cluster 55: Lymphoma - Immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 7 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 16 | 0 | 0 | 0 | [] | [] | [] | 2,478 | 3 |
ENSG00000101343 | CRNKL1 | Crooked neck pre-mRNA splicing factor 1 | [
"Q9BZJ0"
] | 20 | 20034368-20056046 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CLF",
"Clf1",
"CRN",
"SYF3"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [] | [] | [] | [] | [] | null | null | null | 69 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 55: Non-specific - Transcription | Cluster 62: Non-specific - Plasma proteins | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,481 | 2 |
ENSG00000101346 | POFUT1 | Protein O-fucosyltransferase 1 | [
"Q9H488"
] | 20 | 32207855-32238658 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054519",
"HPA059935"
] | [
"FUT12",
"KIAA0180",
"O-Fuc-T",
"O-FUT"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism",
"Fucose metabolism",
"Notch signaling pathway"
] | [
"Glycosyltransferase",
"Transferase"
] | [] | [
"Centrosome"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Approved | Approved | null | 3 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 44: Non-specific - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 26: Kidney & Intestine - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | 2,482 | 7 |
ENSG00000101347 | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 | [
"Q9Y3Z3"
] | 20 | 36890229-36951893 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047072"
] | [
"AGS5",
"HDDC1",
"Mg11",
"MOP-5",
"SBBI88"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"DNA damage",
"DNA repair",
"DNA replication",
"Host-virus interaction",
"Immunity",
"Innate immunity"
] | [
"Allosteric enzyme",
"Hydrolase"
] | [
"Aicardi-Goutieres syndrome",
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Plasma membrane"
] | [] | [] | Supported | Enhanced | null | 28 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 20: Macrophages & Microglia - Immune response | Cluster 44: Connective tissue cells - ECM organization | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,483 | 2 |
ENSG00000101349 | PAK5 | P21 (RAC1) activated kinase 5 | [
"Q9P286"
] | 20 | 9537370-9839076 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020444",
"HPA071060"
] | [
"KIAA1264",
"PAK7"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Apoptosis"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear membrane",
"Mitochondria",
"Cytosol"
] | [] | [] | Supported | Approved | null | 41 | null | null | null | Cluster 2: Neurons - Nucleosome | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Group enriched | Detected in some | 6 | Cancer enriched | Detected in single | 5 | Group enriched | Detected in some | 4 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 2,484 | 6 |
ENSG00000101350 | KIF3B | Kinesin family member 3B | [
"O15066"
] | 20 | 32277651-32335011 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007119"
] | [
"FLA8",
"KIAA0359",
"KLP-11"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Motor protein"
] | [
"Ciliopathy",
"Disease variant",
"Retinitis pigmentosa"
] | [
"Nucleoplasm",
"Primary cilium tip",
"Flagellar centriole"
] | [
"Cytosol",
"Connecting piece"
] | [] | [] | Approved | Approved | null | 15 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 62: Non-specific - Plasma proteins | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 2,485 | 5 |
ENSG00000101353 | MROH8 | Maestro heat like repeat family member 8 | [] | 20 | 37101226-37179588 | Evidence at transcript level | Evidence at transcript level | null | null | [
"HPA058316",
"HPA060298"
] | [
"C20orf131",
"C20orf132",
"dJ621N11.3",
"dJ621N11.4"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Approved | Approved | null | null | null | null | Cluster 30: Non-specific - DNA binding | Cluster 31: Non-specific - Transcription | Cluster 6: Leukemia - Signal transduction | Cluster 55: Myocytes - Oxidative muscle function | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 2,486 | 7 |
ENSG00000101361 | NOP56 | NOP56 ribonucleoprotein | [
"O00567"
] | 20 | 2652593-2658393 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049918",
"CAB075757"
] | [
"NOL5A",
"SCA36"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis"
] | [
"Ribonucleoprotein"
] | [
"Neurodegeneration",
"Spinocerebellar ataxia"
] | [
"Nucleoli fibrillar center"
] | [] | [] | [] | Enhanced | Supported | null | 169 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 14: Neurons - Synaptic function | Cluster 62: Non-specific - Plasma proteins | Cluster 17: Non-specific - RNA processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,487 | 6 |
ENSG00000101363 | MANBAL | Mannosidase beta like | [
"Q9NQG1"
] | 20 | 37289649-37317260 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA052348"
] | [
"dJ1141E15.2"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 20 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 27: Non-specific - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,488 | 6 |
ENSG00000101365 | IDH3B | Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta | [
"O43837"
] | 20 | 2658395-2664219 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049387",
"HPA054180"
] | [
"RP46"
] | [
"Citric acid cycle related proteins",
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Tricarboxylic acid cycle"
] | [] | [
"Disease variant",
"Retinitis pigmentosa"
] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Supported | null | 5 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 62: Non-specific - Plasma proteins | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,489 | 7 |
ENSG00000101367 | MAPRE1 | Microtubule associated protein RP/EB family member 1 | [
"Q15691"
] | 20 | 32819954-32850405 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003600",
"CAB009337",
"CAB019391"
] | [
"EB1"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [
"Centrosome",
"Cytosol"
] | [
"Basal body"
] | [] | [] | Supported | Supported | null | 386 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 27: Non-specific - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,490 | 7 |
ENSG00000101400 | SNTA1 | Syntrophin alpha 1 | [
"Q13424"
] | 20 | 33407957-33443763 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB037059",
"HPA067154"
] | [
"LQT12",
"SNT1",
"TACIP1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding",
"Calmodulin-binding"
] | [
"Disease variant",
"Long QT syndrome"
] | [] | [] | [] | [] | null | Approved | null | 20 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 19: Astrocytes - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 2,493 | 1 |
ENSG00000101405 | OXT | Oxytocin/neurophysin I prepropeptide | [
"P01178"
] | 20 | 3071620-3072517 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA071892"
] | [
"OT",
"OT-NPI",
"OXT-NPI"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Hormone"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Hormone"
] | null | Supported | Supported | 1 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 18: Liver cancer - Metabolism | Cluster 109: Neurons - Neuronal signaling | Cluster 36: Brain & Liver - Signaling | Tissue enriched | Detected in some | 153 | Cancer enriched | Detected in single | 4 | Cancer enriched | Detected in some | 4 | Cell type enriched | Detected in some | 7 | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 2,494 | 7 |
ENSG00000101407 | TTI1 | TELO2 interacting protein 1 | [
"O43156"
] | 20 | 37983007-38033461 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB034230",
"HPA068338"
] | [
"KIAA0406",
"smg-10"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Vesicles"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 51 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 9: Non-specific - Receptor signaling | Cluster 62: Non-specific - Plasma proteins | Cluster 7: Non-specific - Transcription | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,495 | 6 |
ENSG00000101412 | E2F1 | E2F transcription factor 1 | [
"Q01094"
] | 20 | 33675477-33686385 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000329",
"HPA008003",
"CAB019308",
"HPA029735"
] | [
"RBBP3",
"RBP3"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Apoptosis",
"Cell cycle",
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Centrosome"
] | [] | [] | Supported | Enhanced | null | 105 | null | Yes | null | Cluster 34: Non-specific - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 47: Platelets - Hemostasis | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 6 | 2 | 5 | [
"Thyroid Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Thyroid Carcinoma"
] | 2,496 | 7 |
ENSG00000101413 | RPRD1B | Regulation of nuclear pre-mRNA domain containing 1B | [
"Q9NQG5"
] | 20 | 38033725-38127780 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA066290",
"HPA070590",
"HPA072645"
] | [
"C20orf77",
"CREPT",
"dJ1057B20.2",
"DKFZp434P0735",
"FLJ44520",
"K-H",
"Kub5-Hera",
"NET60"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 70 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 55: Non-specific - Transcription | Cluster 62: Non-specific - Plasma proteins | Cluster 7: Non-specific - Transcription | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 2,497 | 9 |
ENSG00000101417 | PXMP4 | Peroxisomal membrane protein 4 | [
"Q9Y6I8"
] | 20 | 33702758-33720319 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA050077"
] | [
"PMP24"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Peroxisomes"
] | [
"Nucleoli fibrillar center"
] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 34: Non-specific - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 81: Alveolar cells - Lung function | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 2,498 | 7 |
ENSG00000101421 | CHMP4B | Charged multivesicular body protein 4B | [
"Q9H444"
] | 20 | 33811348-33854366 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041401",
"HPA051751"
] | [
"C20orf178",
"dJ553F4.4",
"Shax1",
"SNF7-2",
"VPS32B"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Protein transport",
"Transport"
] | [] | [
"Cataract",
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 74 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 62: Non-specific - Plasma proteins | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,499 | 3 |
ENSG00000101425 | BPI | Bactericidal permeability increasing protein | [
"P17213"
] | 20 | 38304150-38337505 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA061284"
] | [
"BPIFD1"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins",
"Transporters"
] | [
"Immunity",
"Innate immunity"
] | [
"Antibiotic",
"Antimicrobial"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Immunity"
] | null | Enhanced | null | 3 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | null | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in some | 87 | Cancer enriched | Detected in some | 4 | Low cancer specificity | Detected in single | null | Group enriched | Detected in some | 4 | Group enriched | Detected in some | 17 | 1 | 0 | 1 | [
"Breast Invasive Carcinoma"
] | [] | [
"Breast Invasive Carcinoma"
] | 2,500 | 3 |
ENSG00000101435 | CST9L | Cystatin 9 like | [
"Q9H4G1"
] | 20 | 23564732-23568484 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"bA218C14.1",
"CTES7B"
] | [
"Predicted secreted proteins"
] | [] | [
"Protease inhibitor",
"Thiol protease inhibitor"
] | [] | [] | [] | [
"Secreted in male reproductive system"
] | [
"Enzyme inhibitor"
] | null | null | null | 25 | null | null | null | null | Cluster 27: Breast cancer - Unknown function | Cluster 10: Epididymal principal cells - Sperm maturation microenvironment | Cluster 22: Epididymis - Mixed function | Group enriched | Detected in some | 295 | Not detected | Not detected | null | Group enriched | Detected in some | 7 | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,501 | 5 |
ENSG00000101439 | CST3 | Cystatin C | [
"P01034"
] | 20 | 23626706-23638473 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000118",
"HPA013143"
] | [] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Protease inhibitor",
"Thiol protease inhibitor"
] | [
"Age-related macular degeneration",
"Amyloidosis",
"Cancer-related genes",
"Disease variant"
] | [
"Golgi apparatus",
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Enzyme inhibitor"
] | Supported | Enhanced | null | 14 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 39: Astrocytes - Mixed function | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 82: Dendritic cells - Antigen presentation | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in all | null | Group enriched | Detected in all | 7 | 3 | 0 | 3 | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,503 | 7 |
ENSG00000101440 | ASIP | Agouti signaling protein | [
"P42127"
] | 20 | 34194569-34269344 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048636"
] | [
"AGTIL",
"ASP"
] | [
"Predicted secreted proteins"
] | [] | [] | [
"Obesity"
] | [
"Vesicles"
] | [
"Flagellar centriole",
"Mid piece"
] | [
"Secreted to blood"
] | [
"No annotated function"
] | Approved | Uncertain | null | null | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 12: Bone cancer - Neuronal signaling | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 75: Ovary - Mixed function | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 340 | 1 | 2 | 0 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,504 | 6 |
ENSG00000101441 | CST4 | Cystatin S | [
"P01036"
] | 20 | 23685640-23689038 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043706",
"HPA044763"
] | [] | [
"Predicted secreted proteins"
] | [] | [
"Protease inhibitor",
"Thiol protease inhibitor"
] | [] | [] | [] | [
"Secreted to digestive system"
] | [
"Enzyme inhibitor"
] | null | Supported | null | 20 | null | null | null | null | Cluster 27: Breast cancer - Unknown function | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 82: Salivary gland - Secretion | Tissue enriched | Detected in some | 514 | Group enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in some | 64 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 2,505 | 1 |
ENSG00000101442 | ACTR5 | Actin related protein 5 | [
"Q9H9F9"
] | 20 | 38748460-38772520 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042676"
] | [
"Arp5",
"FLJ12785",
"INO80M"
] | [
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA recombination",
"DNA repair",
"Transcription",
"Transcription regulation"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 51 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 34: Non-specific - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,506 | 9 |
ENSG00000101443 | WFDC2 | WAP four-disulfide core domain 2 | [
"Q14508"
] | 20 | 45469753-45481532 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042302"
] | [
"dJ461P17.6",
"EDDM4",
"HE4",
"WAP5"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Aspartic protease inhibitor",
"Protease inhibitor",
"Serine protease inhibitor",
"Thiol protease inhibitor"
] | [
"Cancer-related genes",
"Disease variant"
] | [] | [] | [
"Secreted in other tissues"
] | [
"Enzyme inhibitor"
] | null | Enhanced | null | 16 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 38: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | 2,507 | 5 |
ENSG00000101444 | AHCY | Adenosylhomocysteinase | [
"P23526"
] | 20 | 34280268-34311802 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041225",
"HPA044675"
] | [
"AdoHcyase",
"SAHH"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"One-carbon metabolism"
] | [
"Hydrolase"
] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 27 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 27: Non-specific - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 65: Non-specific - Cell growth & division | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,508 | 3 |
ENSG00000101447 | FAM83D | Family with sequence similarity 83 member D | [
"Q9H4H8"
] | 20 | 38926312-38953106 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049333",
"HPA060854"
] | [
"C20orf129",
"CHICA",
"dJ616B8.3"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [
"Proto-oncogene"
] | [
"Mitotic spindle"
] | [
"Microtubules",
"Cytokinetic bridge",
"Cytosol"
] | [] | [] | Supported | null | null | 26 | Yes | Yes | Cluster 16: Non-specific - Cell proliferation | Cluster 53: Neurons - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 84: Apical squamous epithelium - Cornification | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 5 | 4 | 3 | [] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,511 | 3 |
ENSG00000101448 | EPPIN | Epididymal peptidase inhibitor | [
"O95925"
] | 20 | 45540626-45547752 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA067335"
] | [
"CT71",
"dJ461P17.2",
"EPPIN1",
"EPPIN2",
"EPPIN3",
"SPINLW1",
"WAP7",
"WFDC7"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Antimicrobial",
"Protease inhibitor",
"Serine protease inhibitor"
] | [] | [] | [] | [
"Secreted in male reproductive system"
] | [
"Enzyme inhibitor"
] | null | Supported | null | 2 | null | null | null | Cluster 9: Non-specific - Receptor signaling | Cluster 72: Neuronal - Signal transduction | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 22: Epididymis - Mixed function | Tissue enriched | Detected in some | 4 | Low cancer specificity | Detected in single | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Uterine Corpus Endometrial Carcinoma"
] | [
"Uterine Corpus Endometrial Carcinoma"
] | 2,512 | 9 |
ENSG00000101457 | DNTTIP1 | Deoxynucleotidyltransferase terminal interacting protein 1 | [
"Q9H147"
] | 20 | 45791954-45811427 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045496"
] | [
"C20orf167",
"dJ447F3.4",
"Tdif1"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoli",
"Nucleoli rim",
"Mitotic chromosome"
] | [
"Nucleoplasm"
] | [] | [] | Supported | null | null | 35 | Yes | No | Cluster 21: Neutrophils - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 3 | 4 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,514 | 8 |
ENSG00000101460 | MAP1LC3A | Microtubule associated protein 1 light chain 3 alpha | [
"Q9H492"
] | 20 | 34546854-34560345 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007649",
"CAB037174",
"HPA042824",
"HPA052474",
"HPA052484"
] | [
"ATG8E",
"LC3",
"LC3A",
"MAP1ALC3",
"MAP1BLC3"
] | [
"Predicted intracellular proteins"
] | [
"Autophagy",
"Ubl conjugation pathway"
] | [] | [] | [
"Vesicles"
] | [
"Basal body",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 95 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 1: Neurons - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in all | 7 | 3 | 0 | 3 | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,515 | 8 |
ENSG00000101463 | SYNDIG1 | Synapse differentiation inducing 1 | [
"Q9H7V2"
] | 20 | 24469629-24666616 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044271",
"HPA059267"
] | [
"C20orf39",
"DSPC2",
"FLJ14220",
"IFITMD5",
"TMEM90B"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Enhanced | null | null | 14 | null | null | null | Cluster 30: White matter - Myelination | Cluster 1: Neuronal - Visual perception | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in many | 8 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Thyroid Carcinoma"
] | [
"Thyroid Carcinoma"
] | 2,516 | 8 |
ENSG00000101464 | PIGU | Phosphatidylinositol glycan anchor biosynthesis class U | [
"Q9H490"
] | 20 | 34560542-34698790 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041706",
"HPA046766"
] | [
"bA346K17.2",
"CDC91L1",
"GAB1"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"GPI-anchor biosynthesis"
] | [] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 6 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 7: Non-specific - Transcription | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,517 | 8 |
ENSG00000101473 | ACOT8 | Acyl-CoA thioesterase 8 | [
"O14734"
] | 20 | 45841721-45857405 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010261"
] | [
"hACTE-III",
"hTE",
"NAP1",
"PTE-2",
"PTE1"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Fatty acid metabolism",
"Host-virus interaction",
"Lipid metabolism",
"Peroxisome biogenesis"
] | [
"Hydrolase",
"Serine esterase"
] | [] | [
"Vesicles"
] | [
"Mitochondria"
] | [] | [] | Supported | Approved | null | 9 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 14: Neurons - Synaptic function | Cluster 62: Non-specific - Plasma proteins | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,519 | 9 |
ENSG00000101474 | APMAP | Adipocyte plasma membrane associated protein | [
"Q9HDC9"
] | 20 | 24962925-24992751 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA012863",
"HPA064700"
] | [
"BSCv",
"C20orf3"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Approved | null | 13 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 25: Non-specific - Transcription | Cluster 62: Non-specific - Plasma proteins | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 2,520 | 7 |
ENSG00000101489 | CELF4 | CUGBP Elav-like family member 4 | [
"Q9BZC1"
] | 18 | 37243040-37565827 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA013322",
"HPA037986"
] | [
"BRUNOL4"
] | [
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Activator",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | null | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 109: Neurons - Neuronal signaling | Cluster 10: Brain - Synaptic signal transduction | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Uterine Corpus Endometrial Carcinoma"
] | [
"Uterine Corpus Endometrial Carcinoma"
] | 2,521 | 4 |
ENSG00000101493 | ZNF516 | Zinc finger protein 516 | [
"Q92618"
] | 18 | 76357682-76495242 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA015792"
] | [
"HsT287",
"KIAA0222"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 24 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 38: Sub-cortical - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,522 | 3 |
ENSG00000101542 | CDH20 | Cadherin 20 | [
"Q9HBT6"
] | 18 | 61333430-61555779 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [] | [
"Cdh7",
"CDH7L3"
] | [
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 13: Oligodendrocytes - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Cancer enriched | Detected in single | 15 | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 23 | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 2,523 | 9 |
ENSG00000101546 | RBFA | Ribosome binding factor A | [
"Q8N0V3"
] | 18 | 80034389-80050651 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040485",
"HPA041479"
] | [
"C18orf22",
"FLJ21172",
"HsT169"
] | [
"Predicted intracellular proteins"
] | [
"rRNA processing"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | 31 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 13: Non-specific - Mixed function | Cluster 17: Non-specific - RNA processing | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,525 | 5 |
ENSG00000101557 | USP14 | Ubiquitin specific peptidase 14 | [
"P54578"
] | 18 | 158383-214629 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001308"
] | [
"TGT",
"Ubp6"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Immunity",
"Innate immunity",
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Endoplasmic reticulum"
] | [] | [] | Supported | Approved | null | 94 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 49: Hindbrain - Mixed function | Cluster 13: Non-specific - Mixed function | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,526 | 4 |
ENSG00000101558 | VAPA | VAMP associated protein A | [
"Q9P0L0"
] | 18 | 9914016-9960021 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA009174"
] | [
"hVAP-33",
"VAP-A"
] | [
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Host-virus interaction"
] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Enhanced | Approved | null | 368 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 49: Hindbrain - Mixed function | Cluster 13: Non-specific - Mixed function | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,527 | 7 |
ENSG00000101574 | METTL4 | Methyltransferase 4, N6-adenosine | [
"Q8N3J2"
] | 18 | 2537525-2571509 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040061",
"HPA046734"
] | [
"FLJ23017",
"HsT661"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Chromatin regulator",
"Methyltransferase",
"Transferase"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | null | null | Yes | Cluster 21: Neutrophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 13: Non-specific - Mixed function | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,528 | 8 |
ENSG00000101577 | LPIN2 | Lipin 2 | [
"Q92539"
] | 18 | 2885296-3013144 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB015223",
"HPA017857",
"HPA030550"
] | [
"KIAA0249"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism",
"Transcription",
"Transcription regulation"
] | [
"Hydrolase"
] | [
"Congenital dyserythropoietic anemia",
"Disease variant",
"Hereditary hemolytic anemia"
] | [
"Cytosol"
] | [
"Plasma membrane",
"Actin filaments"
] | [] | [] | Approved | Enhanced | null | 4 | Yes | No | Cluster 35: Neutrophils - Protein binding | Cluster 49: Hindbrain - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 2,529 | 5 |
ENSG00000101596 | SMCHD1 | Structural maintenance of chromosomes flexible hinge domain containing 1 | [
"A6NHR9"
] | 18 | 2655726-2805017 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039341",
"HPA039441"
] | [
"FSHD2",
"KIAA0650"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"Chromatin regulator",
"DNA-binding",
"Hydrolase"
] | [
"Disease variant",
"Hypogonadotropic hypogonadism",
"Kallmann syndrome",
"Microphthalmia"
] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Supported | Approved | null | 16 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 25: Non-specific - Transcription | Cluster 13: Non-specific - Mixed function | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 4 | Immune cell enriched | Detected in many | 10 | 0 | 0 | 0 | [] | [] | [] | 2,530 | 3 |
ENSG00000101605 | MYOM1 | Myomesin 1 | [
"P52179"
] | 18 | 3066807-3219968 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014305",
"HPA049193"
] | [] | [
"Predicted intracellular proteins"
] | [] | [
"Muscle protein"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 3 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 55: Myocytes - Oxidative muscle function | Cluster 62: Skeletal muscle - Muscle contraction | Group enriched | Detected in many | 18 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 9 | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,531 | 6 |
ENSG00000101608 | MYL12A | Myosin light chain 12A | [
"P19105"
] | 18 | 3247481-3256236 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004503",
"HPA039262",
"HPA045244",
"HPA059197"
] | [
"MLCB",
"MRCL3",
"MRLC3",
"MYL2B"
] | [
"Predicted intracellular proteins"
] | [] | [
"Motor protein",
"Muscle protein",
"Myosin"
] | [] | [] | [] | [] | [] | null | Supported | null | 24 | null | Yes | Cluster 41: Basophils - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 13: Non-specific - Mixed function | Cluster 47: Platelets - Hemostasis | Cluster 41: Striated muscle - Muscle contraction | Group enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 2,532 | 1 |
ENSG00000101624 | CEP76 | Centrosomal protein 76 | [
"Q8TAP6"
] | 18 | 12661833-12702777 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039395"
] | [
"C18orf9",
"FLJ12542",
"HsT1705"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes"
] | [
"Microtubules",
"Mitotic spindle",
"Primary cilium",
"Perinuclear theca",
"Flagellar centriole"
] | [
"Nucleoplasm",
"Plasma membrane",
"Cytosol"
] | [] | [] | Uncertain | Approved | null | 98 | Yes | null | Cluster 3: Non-specific - Nuclear processes | Cluster 35: Non-specific - DNA binding | Cluster 13: Non-specific - Mixed function | Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe"
] | 2,533 | 6 |
ENSG00000101638 | ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 | [
"O15466"
] | 18 | 46667821-46759257 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043813",
"HPA046771"
] | [
"SIAT8E"
] | [
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Lipid metabolism"
] | [
"Glycosyltransferase",
"Transferase"
] | [] | [
"Plasma membrane",
"Midbody"
] | [] | [] | [] | Approved | Approved | null | 29 | Yes | null | null | Cluster 37: Neurons - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 27: Cerebellum - Synaptic function | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 7 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,534 | 1 |
ENSG00000101639 | CEP192 | Centrosomal protein 192 | [
"Q8TEP8"
] | 18 | 12991362-13125052 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039392",
"HPA040503"
] | [
"FLJ10352",
"KIAA1569",
"PPP1R62"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Centrosome",
"Basal body"
] | [] | [] | Uncertain | Uncertain | null | 36 | Yes | No | Cluster 5: Non-specific - Cell proliferation | Cluster 13: Oligodendrocytes - Mixed function | Cluster 13: Non-specific - Mixed function | Cluster 27: Non-specific - Cell proliferation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Kidney Chromophobe"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe"
] | 2,535 | 7 |
ENSG00000101654 | RNMT | RNA guanine-7 methyltransferase | [
"O43148"
] | 18 | 13726660-13764556 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039409"
] | [
"N7-MTase",
"RG7MT1"
] | [
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"mRNA capping",
"mRNA processing"
] | [
"Methyltransferase",
"RNA-binding",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli fibrillar center"
] | [] | [] | Supported | Approved | null | 20 | null | null | Cluster 24: Non-specific - Transcription | Cluster 23: Choroid plexus - Mixed function | Cluster 13: Non-specific - Mixed function | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 40: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,536 | 4 |
ENSG00000101665 | SMAD7 | SMAD family member 7 | [
"O15105"
] | 18 | 48919853-48950965 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB026212",
"HPA028897"
] | [
"MADH7",
"MADH8"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm",
"Centrosome",
"Basal body"
] | [
"Nucleoli fibrillar center",
"Cytosol"
] | [] | [] | Supported | Approved | null | 58 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 25: Non-specific - Transcription | Cluster 15: Kidney cancer - Membrane components | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,537 | 2 |
ENSG00000101670 | LIPG | Lipase G, endothelial type | [
"Q9Y5X9"
] | 18 | 49560699-49599185 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA016966"
] | [
"EDL"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Lipid degradation",
"Lipid metabolism"
] | [
"Heparin-binding",
"Hydrolase"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Uncertain | null | 29 | null | null | null | Cluster 44: Non-specific - Mixed function | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 43: Placenta - Pregnancy hormone signaling | Group enriched | Detected in many | 6 | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,538 | 8 |
ENSG00000101680 | LAMA1 | Laminin subunit alpha 1 | [
"P25391"
] | 18 | 6941742-7117797 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010179"
] | [
"LAMA"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Cell adhesion"
] | null | Enhanced | null | 2 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 34: Testis cancer - Unknown function | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,539 | 8 |
ENSG00000101695 | RNF125 | Ring finger protein 125 | [
"Q96EQ8"
] | 18 | 32018825-32073219 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041514"
] | [
"FLJ20456"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Adaptive immunity",
"Immunity",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Golgi apparatus"
] | [
"Nucleoli"
] | [] | [] | Supported | Uncertain | null | 25 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 11: White matter - Signal transduction | Cluster 49: HMC-1 - Innate immune response | Cluster 102: Non-specific - Mixed function | Cluster 26: Kidney & Intestine - Metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,540 | 4 |
ENSG00000101745 | ANKRD12 | Ankyrin repeat domain 12 | [
"Q6UB98"
] | 18 | 9136228-9285985 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040705"
] | [
"ANCO-2",
"FLJ20053",
"GAC-1",
"KIAA0874"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 3 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 16: Non-specific - Transcription | Cluster 51: Myeloma - Immunoglobulins | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 40: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 2,541 | 7 |
ENSG00000101752 | MIB1 | MIB E3 ubiquitin protein ligase 1 | [
"Q86YT6"
] | 18 | 21704957-21870953 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019100",
"CAB037044",
"HPA067539"
] | [
"DIP-1",
"KIAA1323",
"MIB",
"ZZANK2",
"ZZZ6"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Notch signaling pathway",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Cardiomyopathy",
"Disease variant"
] | [
"Microtubules",
"Primary cilium"
] | [
"Cytokinetic bridge",
"Mitotic spindle",
"Centriolar satellite",
"Basal body"
] | [] | [] | Approved | Approved | null | 50 | Yes | null | Cluster 41: Basophils - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 2,544 | 7 |
ENSG00000101773 | RBBP8 | RB binding protein 8, endonuclease | [
"Q99708"
] | 18 | 22798261-23026488 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039890",
"HPA052946"
] | [
"COM1",
"CtIP",
"RIM",
"SCKL2"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA damage",
"DNA repair",
"Meiosis",
"Mitosis"
] | [
"DNA-binding",
"Endonuclease",
"Hydrolase",
"Nuclease"
] | [
"Disease variant",
"Dwarfism",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 60 | null | Yes | Cluster 40: Monocytes - Innate immune response | Cluster 23: Choroid plexus - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 103: Non-specific - Basic cellular processes | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | 2,545 | 4 |
ENSG00000101782 | RIOK3 | RIO kinase 3 | [
"O14730"
] | 18 | 23453287-23486603 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001620",
"HPA024184"
] | [
"SUDD"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"Immunity",
"Innate immunity",
"Ribosome biogenesis"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Golgi apparatus",
"Centriolar satellite"
] | [] | [] | Approved | Approved | null | 46 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 28: Oligodendrocytes - Mixed function | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,546 | 4 |
ENSG00000101811 | CSTF2 | Cleavage stimulation factor subunit 2 | [
"P33240"
] | X | 100820391-100841520 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000427",
"CAB004680"
] | [
"CstF-64"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing"
] | [
"RNA-binding"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Enhanced | Supported | null | 58 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 31: Non-specific - Transcription | Cluster 36: Non-specific - mRNA processing | Cluster 84: Apical squamous epithelium - Cornification | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,547 | 8 |
ENSG00000101812 | H2BW2 | H2B.W histone 2 | [
"P0C1H6"
] | X | 104039956-104042454 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"H2BFM",
"H2BM"
] | [
"Predicted intracellular proteins"
] | [] | [
"DNA-binding"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | Cluster 41: Basophils - Unknown function | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 35: RS4;11 - Unknown function | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 61: Non-specific - Transcription | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cancer enhanced | Detected in single | null | Group enriched | Detected in some | 12 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,548 | 9 |
ENSG00000101825 | MXRA5 | Matrix remodeling associated 5 | [
"Q9NR99"
] | X | 3308565-3346652 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000508",
"HPA076518"
] | [
"DKFZp564I1922"
] | [
"Cancer-related genes",
"Disease related genes",
"Predicted secreted proteins"
] | [] | [] | [
"Cancer-related genes"
] | [
"Mitochondria"
] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | Uncertain | Uncertain | null | null | null | null | null | Cluster 12: Non-specific - Vasculature | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,549 | 1 |
ENSG00000101842 | VSIG1 | V-set and immunoglobulin domain containing 1 | [
"Q86XK7"
] | X | 108044970-108079184 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001445",
"HPA036310",
"HPA036311"
] | [
"GPA34",
"MGC44287"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 4 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 53: Neurons - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 68: Foveolar cells - Mucosal defense | Cluster 60: Stomach - Digestion | Tissue enriched | Detected in some | 4 | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 15 | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 2,550 | 7 |
ENSG00000101843 | PSMD10 | Proteasome 26S subunit, non-ATPase 10 | [
"O75832"
] | X | 108084207-108091549 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002920",
"CAB010434"
] | [
"p28"
] | [
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [
"Chaperone"
] | [] | [
"Cytosol",
"Mid piece"
] | [
"Primary cilium tip",
"Perinuclear theca",
"Calyx",
"Principal piece"
] | [] | [] | Supported | Approved | null | 122 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 27: Non-specific - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 97: Non-specific - Cellular respiration | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,551 | 3 |
ENSG00000101844 | ATG4A | Autophagy related 4A cysteine peptidase | [
"Q8WYN0"
] | X | 108091668-108154671 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036374",
"HPA064759"
] | [
"APG4A",
"AUTL2"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Autophagy",
"Lipid metabolism",
"Protein transport",
"Transport",
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Microtubules"
] | [
"Actin filaments"
] | [] | [] | Approved | Uncertain | null | 6 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 21: Non-specific - Metabolism | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 2,552 | 4 |
ENSG00000101846 | STS | Steroid sulfatase | [] | X | 7147237-7804358 | Evidence at protein level | Evidence at protein level | null | null | [
"HPA002904"
] | [
"ARSC",
"ARSC1"
] | [
"Human disease related genes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 51: Myeloma - Immunoglobulins | Cluster 68: Foveolar cells - Mucosal defense | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,553 | 5 |
ENSG00000101850 | GPR143 | G protein-coupled receptor 143 | [
"P51810"
] | X | 9725346-9786297 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003648"
] | [
"OA1"
] | [
"Disease related genes",
"G-protein coupled receptors",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"Albinism",
"Disease variant"
] | [
"Plasma membrane"
] | [
"Nucleoplasm",
"Nuclear bodies",
"Golgi apparatus"
] | [] | [] | Supported | Enhanced | null | 4 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 5 | Cancer enriched | Detected in all | 5 | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 9 | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 2,555 | 5 |
ENSG00000101856 | PGRMC1 | Progesterone receptor membrane component 1 | [
"O00264"
] | X | 119236245-119244466 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002877",
"HPA064724"
] | [
"HPR6.6"
] | [
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [] | [
"Receptor"
] | [] | [
"Endoplasmic reticulum"
] | [
"Nucleoli",
"Mid piece",
"Principal piece"
] | [
"Secreted - unknown location"
] | [
"Receptor"
] | Approved | Enhanced | null | 178 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 47: Platelets - Hemostasis | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,556 | 1 |
ENSG00000101868 | POLA1 | DNA polymerase alpha 1, catalytic subunit | [
"P09884"
] | X | 24693873-24996986 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002947",
"CAB012274"
] | [
"NSX",
"p180",
"POLA"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"DNA replication",
"Host-virus interaction"
] | [
"DNA-binding",
"DNA-directed DNA polymerase",
"Nucleotidyltransferase",
"Transferase"
] | [
"Disease variant",
"Dwarfism",
"FDA approved drug targets",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Supported | null | 25 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 80: Thymus - Adaptive immune response | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,557 | 8 |
ENSG00000101871 | MID1 | Midline 1 | [
"O15344"
] | X | 10445310-10833654 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002878",
"HPA003715"
] | [
"FXY",
"OS",
"RNF59",
"TRIM18"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Disease variant"
] | [
"Centriolar satellite"
] | [
"Golgi apparatus",
"Cytosol"
] | [] | [] | Uncertain | Approved | null | 62 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 15: Non-specific - Transcription | Cluster 72: Neuronal - Signal transduction | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | 2,558 | 1 |
ENSG00000101882 | NKAP | NFKB activating protein | [
"Q8N5F7"
] | X | 119920672-119943751 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000916"
] | [
"FLJ22626"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Notch signaling pathway",
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Supported | null | 58 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 28: Oligodendrocytes - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,559 | 4 |
ENSG00000101883 | RHOXF1 | Rhox homeobox family member 1 | [
"Q8NHV9"
] | X | 120109051-120245267 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052560",
"HPA056506"
] | [
"OTEX",
"PEPP1"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | Approved | null | 1 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 2: Neurons - Nucleosome | Cluster 59: Leukemia - T-cell receptor | Cluster 106: Spermatogonia - Spermatogonial differentiation | Cluster 67: Testis - Mixed function | Tissue enhanced | Detected in many | null | Not detected | Not detected | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 6 | 0 | 0 | 0 | [] | [] | [] | 2,560 | 5 |
ENSG00000101888 | NXT2 | Nuclear transport factor 2 like export factor 2 | [
"Q9NPJ8"
] | X | 109535781-109544698 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024199",
"HPA072010"
] | [
"P15-2"
] | [
"Predicted intracellular proteins"
] | [
"mRNA transport",
"Protein transport",
"Transport"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 17 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 39: Astrocytes - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 17: Non-specific - RNA processing | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 2,561 | 8 |
ENSG00000101890 | GUCY2F | Guanylate cyclase 2F, retinal | [
"P51841"
] | X | 109372906-109482086 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CYGF",
"GC-F",
"GUC2DL",
"RetGC-2",
"ROS-GC2"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"cGMP biosynthesis",
"Sensory transduction",
"Vision"
] | [
"Lyase"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | null | Cluster 5: Rhabdoid - Unknown function | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in single | 143 | Cancer enhanced | Detected in single | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 14 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,562 | 3 |
ENSG00000101892 | ATP1B4 | ATPase Na+/K+ transporting family member beta 4 | [
"Q9UN42"
] | X | 120362085-120383249 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [] | [] | [] | [] | [] | null | null | null | 7 | null | null | null | Cluster 48: Non-specific - Mixed function | null | Cluster 55: Myocytes - Oxidative muscle function | Cluster 30: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in some | 28 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 7 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,563 | 9 |
ENSG00000101898 | MCTS2 | MCTS family member 2 | [
"A0A3B3IRV3"
] | 20 | 31547379-31548081 | Evidence at transcript level | Evidence at transcript level | No human protein/transcript evidence | null | [
"HPA001045"
] | [
"MCTS2P",
"psiMCT-1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | null | null | null | null | null | Cluster 24: Non-specific - Transcription | Cluster 48: Non-specific - Mixed function | Cluster 62: Non-specific - Plasma proteins | null | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Not detected | Not detected | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 2,564 | 7 |
ENSG00000101901 | ALG13 | ALG13 UDP-N-acetylglucosaminyltransferase subunit | [
"Q9NP73"
] | X | 111665811-111760649 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002853",
"HPA005498"
] | [
"CDG1S",
"CXorf45",
"FLJ23018",
"GLT28D1",
"MDS031",
"TDRD13",
"YGL047W"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Glycosyltransferase",
"Hydrolase",
"Multifunctional enzyme",
"Protease",
"Thiol protease",
"Transferase"
] | [
"Congenital disorder of glycosylation",
"Disease variant",
"Epilepsy"
] | [
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 7 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 50: Non-specific - Nucleic acid binding | Cluster 36: Non-specific - mRNA processing | Cluster 103: Non-specific - Basic cellular processes | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 2,565 | 7 |
ENSG00000101911 | PRPS2 | Phosphoribosyl pyrophosphate synthetase 2 | [
"P11908"
] | X | 12791355-12824222 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051269",
"HPA067599",
"CAB070417"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Nucleotide biosynthesis"
] | [
"Kinase",
"Transferase"
] | [] | [
"Vesicles"
] | [
"Nuclear speckles",
"Basal body"
] | [] | [] | Approved | Enhanced | null | 28 | null | null | Cluster 18: Non-specific - Translation | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 36: Non-specific - mRNA processing | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 61: Non-specific - Transcription | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 2,566 | 9 |
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