ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000105127 | AKAP8 | A-kinase anchoring protein 8 | [
"O43823"
] | 19 | 15353385-15379815 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004776"
] | [
"AKAP95",
"DKFZp586B1222"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Immunity",
"Innate immunity",
"Protein transport",
"Transcription",
"Transcription regulation",
"Transport"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 41 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 16: Non-specific - Transcription | Cluster 23: Non-specific - Transcription | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,006 | 7 |
ENSG00000105131 | EPHX3 | Epoxide hydrolase 3 | [
"Q9H6B9"
] | 19 | 15226919-15233435 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA012842"
] | [
"ABHD9",
"FLJ22408"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 1 | null | null | Cluster 10: Non-specific - Membrane trafficking | null | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 81: Squamous epithelium - Keratinization | Group enriched | Detected in many | 6 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 3,007 | 9 |
ENSG00000105135 | ILVBL | IlvB acetolactate synthase like | [
"A1L0T0"
] | 19 | 15114984-15125786 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA067682"
] | [
"209L8",
"AHAS",
"FLJ39061",
"HACL1L",
"ILV2H",
"MGC1269",
"MGC19535"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Lyase"
] | [] | [
"Golgi apparatus",
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 14 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 27: Non-specific - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func. | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,008 | 4 |
ENSG00000105136 | ZNF419 | Zinc finger protein 419 | [
"Q96HQ0"
] | 19 | 57487711-57496098 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA003152",
"HPA003274"
] | [
"ZAPHIR",
"ZNF419A"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli fibrillar center"
] | [] | [] | Approved | Uncertain | null | 3 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 15: Non-specific - Transcription | Cluster 4: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Pancreatic Adenocarcinoma"
] | [
"Prostate Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma",
"Prostate Adenocarcinoma"
] | 3,009 | 9 |
ENSG00000105137 | SYDE1 | Synapse defective Rho GTPase homolog 1 | [
"Q6ZW31"
] | 19 | 15107401-15114985 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA013328"
] | [
"7h3",
"FLJ13511",
"SYD1"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Nucleoplasm"
] | [
"Golgi apparatus",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 6 | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 72: Neuronal - Signal transduction | Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func. | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 5 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | 3,010 | 8 |
ENSG00000105141 | CASP14 | Caspase 14 | [
"P31944"
] | 19 | 15049480-15058293 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010059",
"HPA027062"
] | [
"MGC119078",
"MGC119079",
"MICE"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Differentiation"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Ichthyosis"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Mitochondria"
] | [] | [] | Supported | Enhanced | null | 25 | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 26: Keratinocytes - Keratinization | Cluster 37: Skin - Keratinization | Tissue enriched | Detected in some | 13 | Cancer enriched | Detected in some | 7 | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,011 | 7 |
ENSG00000105143 | SLC1A6 | Solute carrier family 1 member 6 | [
"P48664"
] | 19 | 14950033-15022990 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041505",
"HPA044066"
] | [
"EAAT4"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Amino-acid transport",
"Symport",
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [
"Intermediate filaments"
] | [] | [] | Supported | Enhanced | Supported | null | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling | Cluster 71: Cerebellum - Nervous system development | Tissue enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 7 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | 3,012 | 2 |
ENSG00000105146 | AURKC | Aurora kinase C | [
"Q9UQB9"
] | 19 | 57231009-57235548 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA034859"
] | [
"ARK3",
"AurC",
"STK13"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Meiosis",
"Mitosis"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 8 | null | null | null | Cluster 28: Oligodendrocytes - Mixed function | Cluster 34: Testis cancer - Unknown function | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 47: Testis - Mixed function | Tissue enriched | Detected in many | 9 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,013 | 3 |
ENSG00000105173 | CCNE1 | Cyclin E1 | [
"P24864"
] | 19 | 29811991-29824312 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000308",
"CAB016682",
"HPA018169"
] | [
"CCNE"
] | [
"Cancer-related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division"
] | [
"Cyclin"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | Approved | null | 54 | Yes | Yes | Cluster 40: Monocytes - Innate immune response | Cluster 1: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 6 | Not detected in immune cells | Not detected | null | 6 | 4 | 4 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 3,015 | 6 |
ENSG00000105176 | URI1 | URI1 prefoldin like chaperone | [
"O94763"
] | 19 | 29923644-30016612 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA071709"
] | [
"C19orf2",
"FLJ10575",
"NNX3",
"PPP1R19",
"RMP",
"URI"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Protein phosphatase inhibitor",
"Repressor"
] | [
"Oncogene"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 87 | Yes | No | Cluster 22: Eosinophils - Transcription | Cluster 25: Non-specific - Transcription | Cluster 4: Non-specific - Transcription | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Rectum Adenocarcinoma"
] | 3,016 | 6 |
ENSG00000105185 | PDCD5 | Programmed cell death 5 | [
"O14737"
] | 19 | 32581190-32587453 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018471"
] | [
"MGC9294",
"TFAR19"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Enhanced | null | 25 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 14: Neurons - Synaptic function | Cluster 4: Non-specific - Transcription | Cluster 41: Oocytes - Oogenesis | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 8 | Low immune cell specificity | Detected in all | null | 4 | 4 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,017 | 8 |
ENSG00000105186 | ANKRD27 | Ankyrin repeat domain 27 | [
"Q96NW4"
] | 19 | 32597006-32676597 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042769"
] | [
"DKFZp434L0718",
"FLJ00040",
"VARP"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [
"GTPase activation",
"Guanine-nucleotide releasing factor"
] | [] | [
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 16 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 23: Choroid plexus - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 3,018 | 4 |
ENSG00000105193 | RPS16 | Ribosomal protein S16 | [
"P62249"
] | 19 | 39433137-39435949 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064222"
] | [
"S16"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 588 | No | No | Cluster 43: Non-specific - Transcription & Translation | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,019 | 6 |
ENSG00000105197 | TIMM50 | Translocase of inner mitochondrial membrane 50 | [
"Q3ZCQ8"
] | 19 | 39480412-39493785 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048843",
"HPA056448"
] | [
"TIM50",
"TIM50L"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Protein transport",
"Translocation",
"Transport"
] | [
"RNA-binding"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Nucleoplasm",
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 25 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 14: Neurons - Synaptic function | Cluster 4: Non-specific - Transcription | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,020 | 3 |
ENSG00000105198 | LGALS13 | Galectin 13 | [
"Q9UHV8"
] | 19 | 39602524-39607474 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046803"
] | [
"PLAC8",
"PP13"
] | [
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [
"Hemagglutinin"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 4 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 70: DU4475 - Unknown function | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enriched | Detected in single | 32 | Cancer enriched | Detected in single | 13 | Cancer enriched | Detected in single | 6 | Cell type enriched | Detected in some | 19 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,021 | 1 |
ENSG00000105202 | FBL | Fibrillarin | [
"P22087"
] | 19 | 39834458-39846379 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB001514",
"HPA049546",
"HPA077724"
] | [
"FIB",
"FLRN",
"Nop1",
"RNU3IP1"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"rRNA processing"
] | [
"Methyltransferase",
"Ribonucleoprotein",
"RNA-binding",
"Transferase"
] | [] | [
"Nucleoli fibrillar center"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Supported | null | 231 | null | null | Cluster 24: Non-specific - Transcription | Cluster 7: Non-specific - Ribosome | Cluster 4: Non-specific - Transcription | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,022 | 6 |
ENSG00000105204 | DYRK1B | Dual specificity tyrosine phosphorylation regulated kinase 1B | [
"Q9Y463"
] | 19 | 39825350-39834201 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028522",
"HPA028786"
] | [
"MIRK"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Diabetes mellitus",
"Obesity"
] | [
"Nucleoplasm"
] | [
"Mitotic chromosome"
] | [] | [] | Supported | Uncertain | null | 51 | Yes | No | Cluster 13: Non-specific - Mitochondria | Cluster 38: Sub-cortical - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 3,023 | 1 |
ENSG00000105205 | CLC | Charcot-Leyden crystal galectin | [
"Q05315"
] | 19 | 39731255-39738029 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041751"
] | [
"Gal-10",
"LGALS10",
"MGC149659"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | Cluster 22: Eosinophils - Transcription | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 49: HMC-1 - Innate immune response | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in many | 11 | Cancer enriched | Detected in single | 327 | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in some | 5 | Group enriched | Detected in all | 312 | 0 | 0 | 0 | [] | [] | [] | 3,024 | 7 |
ENSG00000105219 | CCNP | Cyclin P | [
"Q9H8S5"
] | 19 | 40222208-40226697 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [
"HPA045615"
] | [
"CNTD2",
"FLJ13265"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | Cluster 46: Basophils - Proteolysis | Cluster 35: Non-specific - DNA binding | Cluster 7: Liver cancer - Metabolism | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 64: Non-specific - Transcription | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 46 | 0 | 0 | 0 | [] | [] | [] | 3,025 | 3 |
ENSG00000105221 | AKT2 | AKT serine/threonine kinase 2 | [
"P31751"
] | 19 | 40230317-40285536 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004204",
"HPA064521",
"HPA069327",
"CAB080295"
] | [
"PKBbeta"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Apoptosis",
"Carbohydrate metabolism",
"Glucose metabolism",
"Glycogen biosynthesis",
"Glycogen metabolism",
"Sugar transport",
"Translation regulation",
"Transport"
] | [
"Developmental protein",
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Cancer-related genes",
"Diabetes mellitus",
"Disease variant",
"Proto-oncogene"
] | [
"Vesicles",
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | Uncertain | null | 23 | null | null | Cluster 34: B-cells - Unknown function | Cluster 48: Non-specific - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 89: Adipocytes - Lipid metabolism | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 3,027 | 6 |
ENSG00000105223 | PLD3 | Phospholipase D family member 3 | [
"Q8IV08"
] | 19 | 40348456-40389472 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012800",
"CAB020812"
] | [
"HU-K4"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Immunity",
"Inflammatory response",
"Lipid metabolism",
"Phospholipid metabolism"
] | [
"Exonuclease",
"Hydrolase",
"Nuclease"
] | [
"Disease variant",
"Neurodegeneration",
"Spinocerebellar ataxia"
] | [
"Endoplasmic reticulum",
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 26 | null | null | Cluster 41: Basophils - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 15: Kidney cancer - Membrane components | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 20: Pituitary gland - Hormone signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enriched | Detected in all | 5 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,028 | 7 |
ENSG00000105227 | PRX | Periaxin | [
"Q9BXM0"
] | 19 | 40393766-40414793 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001868"
] | [
"KIAA1620"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Charcot-Marie-Tooth disease",
"Dejerine-Sottas syndrome",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Golgi apparatus",
"Vesicles",
"Plasma membrane"
] | [] | [] | [] | Approved | Enhanced | null | 3 | null | null | null | Cluster 47: Endothelial cells - Vasculature | Cluster 5: Rhabdoid - Unknown function | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 3,029 | 9 |
ENSG00000105229 | PIAS4 | Protein inhibitor of activated STAT 4 | [
"Q8N2W9"
] | 19 | 4007736-4039386 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA010598",
"HPA076008"
] | [
"FLJ12419",
"Piasg",
"PIASY",
"ZMIZ6"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway",
"Wnt signaling pathway"
] | [
"DNA-binding",
"Repressor",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Centrosome"
] | [] | [] | Supported | Enhanced | null | 83 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 6: Non-specific - Immune response | Cluster 23: Non-specific - Transcription | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 3,030 | 2 |
ENSG00000105245 | NUMBL | NUMB like endocytic adaptor protein | [
"Q9Y6R0"
] | 19 | 40665905-40690972 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA058251",
"HPA058380"
] | [
"CAG3A",
"CTG3a",
"NUMB-R",
"NUMBLIKE",
"NUMBR",
"TNRC23"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Neurogenesis",
"Ubl conjugation pathway"
] | [
"Developmental protein"
] | [] | [] | [] | [] | [] | null | Approved | null | 37 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 5 | 2 | 4 | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,031 | 2 |
ENSG00000105246 | EBI3 | Epstein-Barr virus induced 3 | [
"Q14213"
] | 19 | 4229523-4237528 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046635"
] | [
"IL27B",
"IL35B"
] | [
"Predicted secreted proteins"
] | [] | [
"Cytokine"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Cytokine"
] | null | Enhanced | null | null | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 20: Macrophages & Microglia - Immune response | Cluster 55: Lymphoma - Immune response | Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func. | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enriched | Detected in many | 4 | Cancer enriched | Detected in many | 4 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in some | 13 | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,032 | 4 |
ENSG00000105248 | YJU2 | YJU2 splicing factor homolog | [
"Q9BW85"
] | 19 | 4247080-4269088 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043606",
"HPA055675"
] | [
"CCDC94",
"FLJ10374"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 26 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 13: Oligodendrocytes - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 7: Non-specific - Transcription | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Lung Squamous Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [] | [
"Lung Squamous Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 3,033 | 1 |
ENSG00000105251 | SHD | Src homology 2 domain containing transforming protein D | [
"Q96IW2"
] | 19 | 4279266-4290722 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA017955"
] | [] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Centriolar satellite",
"Cytosol"
] | [] | [] | [] | Uncertain | Uncertain | null | 4 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 41: Oocytes - Oogenesis | Cluster 35: Non-specific - Mixed function | Group enriched | Detected in some | 7 | Cancer enriched | Detected in some | 7 | Cancer enriched | Detected in some | 7 | Cell type enriched | Detected in some | 7 | Immune cell enriched | Detected in single | 179 | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 3,034 | 1 |
ENSG00000105254 | TBCB | Tubulin folding cofactor B | [
"Q99426"
] | 19 | 36114289-36125947 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041428",
"HPA041722"
] | [
"CG22",
"CKAP1",
"CKAPI"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Chaperone",
"Developmental protein"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 14 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 30: White matter - Myelination | Cluster 4: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,035 | 3 |
ENSG00000105255 | FSD1 | Fibronectin type III and SPRY domain containing 1 | [
"Q9BTV5"
] | 19 | 4304598-4323843 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043141"
] | [
"MGC3213",
"MIR1"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Supported | null | null | null | null | Cluster 24: Non-specific - Transcription | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in some | 5 | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in some | 5 | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | 3,036 | 7 |
ENSG00000105258 | POLR2I | RNA polymerase II subunit I | [
"P36954"
] | 19 | 36113709-36115213 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035632",
"HPA045156"
] | [
"hRPB14.5",
"RPB9"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins",
"RNA polymerase related proteins"
] | [
"Transcription"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 76 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 3,037 | 6 |
ENSG00000105261 | OVOL3 | Ovo like zinc finger 3 | [
"O00110"
] | 19 | 36111143-36113711 | Evidence at transcript level | Evidence at transcript level | No human protein/transcript evidence | Evidence at transcript level | [
"HPA047540"
] | [
"HOVO3"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Approved | null | null | null | null | null | Cluster 22: Eosinophils - Transcription | Cluster 6: Non-specific - Immune response | Cluster 46: Lymphoma - Humoral immune response | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 47: Testis - Mixed function | Tissue enriched | Detected in single | 4 | Low cancer specificity | Detected in single | null | Low cancer specificity | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,038 | 5 |
ENSG00000105270 | CLIP3 | CAP-Gly domain containing linker protein 3 | [
"Q96DZ5"
] | 19 | 36014660-36033343 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA079430"
] | [
"CLIPR-59",
"RSNL1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 9 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 1: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cancer enriched | Detected in all | 4 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,039 | 3 |
ENSG00000105281 | SLC1A5 | Solute carrier family 1 member 5 | [
"Q15758"
] | 19 | 46774883-46788594 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035239",
"HPA035240"
] | [
"AAAT",
"ASCT2",
"M7V1",
"RDRC"
] | [
"FDA approved drug targets",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Amino-acid transport",
"Antiport",
"Host-virus interaction",
"Symport",
"Transport"
] | [
"Host cell receptor for virus entry",
"Receptor"
] | [
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [
"Centriolar satellite",
"Basal body"
] | [] | [] | Supported | Enhanced | null | 33 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 49: Hindbrain - Mixed function | Cluster 32: Non-specific - Cell proliferation | Cluster 103: Non-specific - Basic cellular processes | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,041 | 7 |
ENSG00000105287 | PRKD2 | Protein kinase D2 | [
"Q9BZL6"
] | 19 | 46674275-46717127 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021490",
"HPA056727"
] | [
"DKFZP586E0820",
"HSPC187",
"PKD2"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Adaptive immunity",
"Angiogenesis",
"Cell adhesion",
"Immunity"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 29 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 51: Myeloma - Immunoglobulins | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,042 | 6 |
ENSG00000105289 | TJP3 | Tight junction protein 3 | [
"O95049"
] | 19 | 3708362-3750813 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013244",
"HPA046863",
"HPA053337"
] | [
"ZO-3"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [] | [] | [] | [
"Nucleoplasm",
"Cell Junctions"
] | [
"Plasma membrane"
] | [] | [] | Enhanced | Enhanced | null | 1 | null | null | Cluster 11: T-cells - Unknown function | Cluster 36: Choroid plexus - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 1 | 0 | 1 | [
"Stomach Adenocarcinoma"
] | [] | [
"Stomach Adenocarcinoma"
] | 3,043 | 5 |
ENSG00000105290 | APLP1 | Amyloid beta precursor like protein 1 | [
"P51693"
] | 19 | 35867899-35879792 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028970",
"HPA028971"
] | [
"APLP"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis",
"Cell adhesion",
"Endocytosis"
] | [
"Heparin-binding"
] | [
"Neurodegeneration"
] | [
"Golgi apparatus",
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Enhanced | null | 16 | null | null | null | Cluster 30: White matter - Myelination | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in many | 8 | Cancer enhanced | Detected in all | null | Group enriched | Detected in all | 4 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,044 | 7 |
ENSG00000105298 | CACTIN | Cactin, spliceosome C complex subunit | [
"Q8WUQ7"
] | 19 | 3610645-3626815 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042504",
"HPA042548"
] | [
"C19orf29",
"fSAPc",
"NY-REN-24"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Immunity",
"Innate immunity",
"mRNA processing",
"mRNA splicing"
] | [
"Developmental protein"
] | [] | [
"Nucleoplasm",
"Nuclear speckles"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 10 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 32: Cerebral cortex - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 20: Non-specific - Transcription regulation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Bladder Urothelial Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma"
] | 3,045 | 7 |
ENSG00000105321 | CCDC9 | Coiled-coil domain containing 9 | [
"Q9Y3X0"
] | 19 | 47255980-47273701 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045624",
"HPA072007"
] | [
"DKFZP586M1019"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 19 | null | null | Cluster 19: Eosinophils - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma"
] | 3,046 | 2 |
ENSG00000105323 | HNRNPUL1 | Heterogeneous nuclear ribonucleoprotein U like 1 | [
"Q9BUJ2"
] | 19 | 41262496-41307787 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046290",
"CAB046477",
"HPA049475"
] | [
"E1B-AP5",
"E1BAP5",
"FLJ12944",
"HNRPUL1"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Repressor",
"Ribonucleoprotein",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 78 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 4: Non-specific - Transcription | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 3,047 | 6 |
ENSG00000105325 | FZR1 | Fizzy and cell division cycle 20 related 1 | [
"Q9UM11"
] | 19 | 3506311-3538334 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043536"
] | [
"CDC20C",
"CDH1",
"FZR",
"FZR2",
"HCDH",
"HCDH1",
"KIAA1242"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA damage",
"DNA repair",
"Mitosis",
"Ubl conjugation pathway"
] | [] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Nucleoplasm",
"Nuclear membrane"
] | [] | [] | [] | Supported | Approved | null | 127 | null | Yes | Cluster 22: Eosinophils - Transcription | Cluster 1: Neurons - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,048 | 8 |
ENSG00000105327 | BBC3 | BCL2 binding component 3 | [
"Q96PG8",
"Q9BXH1"
] | 19 | 47220822-47232766 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB007752",
"HPA070403"
] | [
"JFY1",
"PUMA"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 25 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 15: Non-specific - Transcription | Cluster 25: Non-specific - Ribosome | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 6 | 1 | 0 | 1 | [
"Bladder Urothelial Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma"
] | 3,049 | 4 |
ENSG00000105329 | TGFB1 | Transforming growth factor beta 1 | [] | 19 | 41301587-41353922 | Evidence at transcript level | Evidence at transcript level | null | null | [
"CAB000361",
"HPA073356"
] | [
"CED",
"DPD1",
"TGFB",
"TGFbeta"
] | [
"Human disease related genes",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Golgi apparatus",
"Plasma membrane"
] | [
"Basal body"
] | [
"Secreted to blood"
] | [] | Approved | Approved | null | 16 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 43: Hindbrain - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 20: Non-specific - Transcription regulation | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 3,050 | 7 |
ENSG00000105339 | DENND3 | DENN domain containing 3 | [
"A2RUS2"
] | 8 | 141117278-141195808 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA024491",
"HPA041668"
] | [
"KIAA0870"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Approved | null | Approved | null | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 20: Macrophages & Microglia - Immune response | Cluster 6: Leukemia - Signal transduction | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 3,051 | 4 |
ENSG00000105341 | DMAC2 | Distal membrane arm assembly component 2 | [
"Q9NW81"
] | 19 | 41431318-41440717 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041427"
] | [
"ATP5SL",
"FLJ10241"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 45: Non-specific - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 27: Non-specific - Cell proliferation | Cluster 41: Striated muscle - Muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,052 | 3 |
ENSG00000105352 | CEACAM4 | CEA cell adhesion molecule 4 | [
"O75871"
] | 19 | 41619015-41627074 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CGM7"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | null | null | null | Cluster 21: Neutrophils - Unknown function | null | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 5: Spleen - Immune response | Tissue enriched | Detected in some | 5 | Not detected | Not detected | null | Low cancer specificity | Detected in single | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 3,053 | 6 |
ENSG00000105355 | PLIN3 | Perilipin 3 | [
"O60664"
] | 19 | 4838341-4867694 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006427",
"HPA066538"
] | [
"M6PRBP1",
"PP17",
"TIP47"
] | [
"FDA approved drug targets",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transport"
] | [] | [
"FDA approved drug targets"
] | [
"Lipid droplets"
] | [] | [] | [] | Supported | Uncertain | null | 26 | null | Yes | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 30: White matter - Myelination | Cluster 72: Neuronal - Signal transduction | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 6 | 0 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,054 | 9 |
ENSG00000105357 | MYH14 | Myosin heavy chain 14 | [
"Q7Z406"
] | 19 | 50188186-50310542 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA062391",
"HPA067889",
"HPA070260"
] | [
"DFNA4",
"FLJ13881",
"KIAA2034",
"MHC16",
"MYH17"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell shape"
] | [
"Actin-binding",
"Calmodulin-binding",
"Motor protein",
"Myosin"
] | [
"Deafness",
"Disease variant",
"Neuropathy",
"Non-syndromic deafness"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Enhanced | null | 22 | null | null | null | Cluster 45: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 3,055 | 2 |
ENSG00000105364 | MRPL4 | Mitochondrial ribosomal protein L4 | [
"Q9BYD3"
] | 19 | 10251901-10260055 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051261"
] | [
"CGI-28"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [] | [] | [] | [] | null | Approved | null | 49 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 23: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,056 | 9 |
ENSG00000105366 | SIGLEC8 | Sialic acid binding Ig like lectin 8 | [
"Q9NYZ4"
] | 19 | 51450847-51458456 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA012556"
] | [
"MGC59785",
"SAF2",
"SIGLEC-8",
"SIGLEC8L"
] | [
"CD markers",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Uncertain | Uncertain | null | 1 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 20: Macrophages & Microglia - Immune response | Cluster 49: HMC-1 - Innate immune response | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in single | 7 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in some | 38 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,057 | 5 |
ENSG00000105369 | CD79A | CD79a molecule | [
"P11912"
] | 19 | 41877279-41881372 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000019",
"HPA056444"
] | [
"Ig-alpha",
"IGA",
"IGAlpha",
"MB-1",
"MB1"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Adaptive immunity",
"Immunity"
] | [
"Receptor"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Enhanced | null | 166 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 46: Lymphoma - Humoral immune response | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 18: Lymphoid tissue - Immune response | Group enriched | Detected in many | 5 | Cancer enriched | Detected in many | 4 | Low cancer specificity | Detected in many | null | Group enriched | Detected in some | 13 | Group enriched | Detected in many | 38 | 2 | 0 | 2 | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | 3,058 | 6 |
ENSG00000105370 | LIM2 | Lens intrinsic membrane protein 2 | [
"P55344"
] | 19 | 51379909-51387974 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"MP17",
"MP19"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [
"Eye lens protein"
] | [
"Cataract",
"Disease variant"
] | [] | [] | [] | [] | null | null | null | null | null | null | Cluster 15: NK-cells - Unknown function | null | Cluster 54: Non-specific - Transcription | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | null | Not detected | Not detected | null | Cancer enriched | Detected in single | 7 | Cancer enriched | Detected in single | 36 | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in some | 7 | 0 | 0 | 0 | [] | [] | [] | 3,059 | 6 |
ENSG00000105372 | RPS19 | Ribosomal protein S19 | [
"P39019"
] | 19 | 41860255-41872925 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA063217"
] | [
"DBA",
"eS19",
"LOH19CR1",
"S19"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [
"Host-virus interaction"
] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [
"Diamond-Blackfan anemia",
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 344 | null | null | Cluster 18: Non-specific - Translation | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 3,061 | 6 |
ENSG00000105373 | NOP53 | NOP53 ribosome biogenesis factor | [
"Q9NZM5"
] | 19 | 47745546-47757058 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018999",
"HPA049600"
] | [
"GLTSCR2",
"PICT-1",
"PICT1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Ribosome biogenesis"
] | [] | [] | [
"Nucleoli"
] | [] | [] | [] | Supported | Approved | null | 103 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 47: Endothelial cells - Vasculature | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 3,062 | 6 |
ENSG00000105376 | ICAM5 | Intercellular adhesion molecule 5 | [
"Q9UMF0"
] | 19 | 10289952-10296778 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008943",
"HPA009083",
"CAB025178"
] | [
"TLCN",
"TLN"
] | [
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 42 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 73: Brain - Neuronal signaling | Tissue enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 3,064 | 9 |
ENSG00000105379 | ETFB | Electron transfer flavoprotein subunit beta | [
"P38117"
] | 19 | 51345169-51366388 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018910",
"HPA018921",
"HPA018923"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Electron transport",
"Transport"
] | [] | [
"Disease variant",
"Glutaricaciduria"
] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Supported | null | 24 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 27: Non-specific - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 97: Non-specific - Cellular respiration | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | 3,065 | 7 |
ENSG00000105383 | CD33 | CD33 molecule | [
"P20138"
] | 19 | 51225064-51243860 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011442",
"HPA035832",
"CAB079996",
"CAB080305"
] | [
"FLJ00391",
"p67",
"SIGLEC-3",
"SIGLEC3"
] | [
"CD markers",
"FDA approved drug targets",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 24 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 20: Macrophages & Microglia - Immune response | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 8 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in many | 7 | 0 | 0 | 0 | [] | [] | [] | 3,066 | 9 |
ENSG00000105388 | CEACAM5 | CEA cell adhesion molecule 5 | [
"P06731"
] | 19 | 41708585-41730433 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000021",
"CAB000022",
"HPA011041",
"HPA019758"
] | [
"CD66e",
"CEA"
] | [
"Cancer-related genes",
"CD markers",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis",
"Cell adhesion"
] | [] | [
"Cancer-related genes",
"Oncogene"
] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 1 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 17: Intestine - Digestion | Tissue enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,067 | 6 |
ENSG00000105393 | BABAM1 | BRISC and BRCA1 A complex member 1 | [
"Q9NWV8"
] | 19 | 17267376-17281249 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054386",
"HPA068786",
"HPA077609"
] | [
"C19orf62",
"FLJ20571",
"HSPC142",
"MERIT40",
"NBA1"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA damage",
"DNA repair",
"Mitosis",
"Ubl conjugation pathway"
] | [
"Chromatin regulator"
] | [] | [
"Nuclear bodies"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Approved | null | 21 | No | No | Cluster 29: Non-specific - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 23: Non-specific - Transcription | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Skin Cutaneous Melanoma"
] | [
"Skin Cutaneous Melanoma"
] | 3,069 | 9 |
ENSG00000105397 | TYK2 | Tyrosine kinase 2 | [
"P29597"
] | 19 | 10350533-10380608 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005157"
] | [
"JTK1"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [
"FDA approved drug targets"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 28 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 19: Astrocytes - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,070 | 8 |
ENSG00000105398 | SULT2A1 | Sulfotransferase family 2A member 1 | [
"Q06520"
] | 19 | 47870467-47886315 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB018755",
"HPA041487",
"HPA063633"
] | [
"DHEA-ST",
"STD"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Bile acid catabolism",
"Lipid degradation",
"Lipid metabolism",
"Steroid metabolism"
] | [
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 5 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 4 | Cancer enriched | Detected in single | 8 | Cancer enriched | Detected in some | 36 | Cell type enriched | Detected in some | 8 | Immune cell enhanced | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 3,071 | 8 |
ENSG00000105401 | CDC37 | Cell division cycle 37, HSP90 cochaperone | [
"Q16543"
] | 19 | 10391133-10420121 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003928",
"CAB004214"
] | [
"P50CDC37"
] | [
"Cancer-related genes",
"Essential proteins",
"Predicted intracellular proteins",
"Transporters"
] | [] | [
"Chaperone"
] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Supported | null | 411 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 23: Non-specific - Transcription | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,072 | 7 |
ENSG00000105402 | NAPA | NSF attachment protein alpha | [
"P54920"
] | 19 | 47487637-47515091 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010100",
"HPA046149",
"HPA050196"
] | [] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Uncertain | Approved | null | 159 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 4: Non-specific - Transcription | Cluster 65: Non-specific - Cell growth & division | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,073 | 7 |
ENSG00000105404 | RABAC1 | Rab acceptor 1 | [
"Q9UI14"
] | 19 | 41956681-41959321 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB019320",
"HPA029171"
] | [
"PRA1",
"PRAF1",
"YIP3"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [] | [] | [] | [] | null | Supported | null | 88 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 45: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 8: Non-specific - Secretory pathway | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 3,074 | 8 |
ENSG00000105409 | ATP1A3 | ATPase Na+/K+ transporting subunit alpha 3 | [
"P13637"
] | 19 | 41966582-41997497 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB033630",
"HPA045367",
"HPA056446"
] | [
"DYT12"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Potassium transport",
"Sodium transport",
"Sodium/potassium transport",
"Transport"
] | [
"Translocase"
] | [
"Deafness",
"Disease variant",
"Dystonia",
"Epilepsy",
"Intellectual disability",
"Parkinsonism"
] | [] | [] | [] | [] | null | Enhanced | Approved | 120 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 1: Neuronal - Visual perception | Cluster 109: Neurons - Neuronal signaling | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in some | 8 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 6 | Group enriched | Detected in some | 8 | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Skin Cutaneous Melanoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma",
"Skin Cutaneous Melanoma"
] | 3,075 | 9 |
ENSG00000105419 | MEIS3 | Meis homeobox 3 | [
"Q99687"
] | 19 | 47403124-47419527 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046699"
] | [
"DKFZp547H236",
"MRG2"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 65: Brain - Transcription | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,076 | 7 |
ENSG00000105426 | PTPRS | Protein tyrosine phosphatase receptor type S | [
"Q13332"
] | 19 | 5158495-5340812 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA054747"
] | [] | [
"Enzymes",
"Plasma proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [
"Heparin-binding",
"Hydrolase",
"Protein phosphatase",
"Receptor"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [
"Secreted - unknown location"
] | [
"Receptor"
] | Approved | null | null | 9 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 32: Cerebral cortex - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 108: Fibroblasts - ECM organization | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 197 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,077 | 8 |
ENSG00000105427 | CNFN | Cornifelin | [
"Q9BYD5"
] | 19 | 42387019-42390297 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049073",
"HPA053997"
] | [
"PLAC8L2"
] | [
"Predicted intracellular proteins"
] | [
"Keratinization"
] | [] | [] | [
"Microtubules"
] | [
"Cytokinetic bridge"
] | [] | [] | Approved | Enhanced | null | 10 | Yes | No | Cluster 18: Non-specific - Translation | Cluster 33: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 84: Apical squamous epithelium - Cornification | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enriched | Detected in many | 80 | Group enriched | Detected in many | 11 | 1 | 0 | 1 | [
"Thyroid Carcinoma"
] | [] | [
"Thyroid Carcinoma"
] | 3,078 | 7 |
ENSG00000105428 | ZNRF4 | Zinc and ring finger 4 | [
"Q8WWF5"
] | 19 | 5455417-5456856 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"RNF204",
"spzn",
"Ssrzf1"
] | [
"Enzymes",
"Predicted membrane proteins"
] | [] | [
"Transferase"
] | [] | [] | [] | [] | [] | null | null | null | 8 | null | null | null | null | Cluster 47: Leukemia - Hemostasis | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in single | 455 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in some | 210 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,079 | 1 |
ENSG00000105429 | MEGF8 | Multiple EGF like domains 8 | [
"Q7Z7M0"
] | 19 | 42325609-42378769 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049248"
] | [
"C19orf49",
"EGFL4",
"FLJ22365",
"SBP1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [
"Craniosynostosis",
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | 5 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 4: Non-specific - Transcription | Cluster 109: Neurons - Neuronal signaling | Cluster 10: Brain - Synaptic signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 3,080 | 2 |
ENSG00000105443 | CYTH2 | Cytohesin 2 | [
"Q99418"
] | 19 | 48469208-48482314 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB014872",
"HPA060662"
] | [
"ARNO",
"CTS18.1",
"cytohesin-2",
"PSCD2",
"PSCD2L",
"Sec7p-L",
"Sec7p-like"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Cytosol"
] | [
"Golgi apparatus",
"Plasma membrane"
] | [] | [] | Supported | Uncertain | null | 23 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 6: Non-specific - Immune response | Cluster 56: Non-specific - Sensory perception | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 47: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,082 | 7 |
ENSG00000105447 | GRWD1 | Glutamate rich WD repeat containing 1 | [
"Q9BQ67"
] | 19 | 48445841-48457022 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042643",
"HPA055680"
] | [
"GRWD",
"RRB1",
"WDR28"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"DNA replication"
] | [] | [] | [
"Nucleoli",
"Nucleoli rim"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | Approved | null | 47 | No | No | Cluster 30: Non-specific - DNA binding | Cluster 38: Sub-cortical - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,083 | 1 |
ENSG00000105464 | GRIN2D | Glutamate ionotropic receptor NMDA type subunit 2D | [
"O15399"
] | 19 | 48393668-48444931 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB009006"
] | [
"EB11",
"GluN2D",
"NMDAR2D",
"NR2D"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted membrane proteins"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"Disease variant",
"Epilepsy",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 109: Neurons - Neuronal signaling | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Bladder Urothelial Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,084 | 2 |
ENSG00000105467 | SYNGR4 | Synaptogyrin 4 | [
"O95473"
] | 19 | 48364367-48376377 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA030075",
"HPA059286"
] | [] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Enhanced | null | 1 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 40: Non-specific - Unknown function | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 23: Testis - Spermatogenesis | Tissue enriched | Detected in some | 8 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,085 | 5 |
ENSG00000105472 | CLEC11A | C-type lectin domain containing 11A | [
"Q9Y240"
] | 19 | 50723364-50725708 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042690"
] | [
"CLECSF3",
"LSLCL",
"P47",
"SCGF"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Osteogenesis"
] | [
"Growth factor"
] | [] | [
"Centrosome"
] | [] | [
"Secreted in other tissues"
] | [
"Growth factor"
] | Approved | Approved | null | 58 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 35: RS4;11 - Unknown function | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 3,086 | 4 |
ENSG00000105479 | ODAD1 | Outer dynein arm docking complex subunit 1 | [
"Q96M63"
] | 19 | 48296457-48321971 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042524"
] | [
"CCDC114",
"CILD20",
"FLJ32926"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Ciliopathy",
"Disease variant",
"Kartagener syndrome",
"Primary ciliary dyskinesia"
] | [
"Mid piece"
] | [
"Connecting piece",
"Principal piece"
] | [] | [] | Supported | Approved | null | 11 | null | null | null | Cluster 3: Choroid plexus - Cilium | Cluster 10: Ciliated cells - Ion channel activity | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 56: Ciliated tissues - Cilium organization | Group enriched | Detected in some | 4 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Ovary Serous Cystadenocarcinoma"
] | 3,087 | 4 |
ENSG00000105483 | CARD8 | Caspase recruitment domain family member 8 | [
"Q9Y2G2"
] | 19 | 48180770-48255946 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042071",
"HPA043513"
] | [
"CARDINAL",
"Dakar",
"KIAA0955",
"NDPP",
"TUCAN"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Immunity",
"Inflammatory response",
"Innate immunity",
"Necrosis"
] | [
"Hydrolase",
"Protease"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 1 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 42: Choroid plexus - Mitochondria | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 3,088 | 8 |
ENSG00000105486 | LIG1 | DNA ligase 1 | [
"P18858"
] | 19 | 48115445-48170603 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB037015",
"HPA041431",
"HPA048071"
] | [
"hLig1",
"LIGI"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA damage",
"DNA recombination",
"DNA repair",
"DNA replication"
] | [
"Ligase"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Golgi apparatus",
"Vesicles"
] | [] | [] | Supported | Approved | null | 10 | Yes | No | Cluster 16: Non-specific - Cell proliferation | null | Cluster 4: Non-specific - Transcription | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Skin Cutaneous Melanoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 3,089 | 9 |
ENSG00000105492 | SIGLEC6 | Sialic acid binding Ig like lectin 6 | [
"O43699"
] | 19 | 51517819-51531856 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008945",
"HPA009084",
"HPA018198"
] | [
"CD327",
"CD33L",
"CD33L1",
"OB-BP1",
"SIGLEC-6"
] | [
"CD markers",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [
"Secreted to blood"
] | [
"Cell adhesion"
] | Approved | Enhanced | null | 2 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 48: Non-specific - Mixed function | Cluster 49: HMC-1 - Innate immune response | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enriched | Detected in many | 24 | Group enriched | Detected in some | 5 | Group enriched | Detected in some | 4 | Group enriched | Detected in some | 16 | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 3,090 | 6 |
ENSG00000105497 | ZNF175 | Zinc finger protein 175 | [
"Q9Y473"
] | 19 | 51571283-51592510 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002717",
"HPA074615"
] | [
"OTK18"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Antiviral defense",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoli"
] | [
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 4 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 38: Sub-cortical - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 47: Platelets - Hemostasis | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,091 | 4 |
ENSG00000105499 | PLA2G4C | Phospholipase A2 group IVC | [
"Q9UP65"
] | 19 | 48047843-48110817 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043083"
] | [
"cPLA2-gamma"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Host-virus interaction",
"Lipid metabolism",
"Phospholipid metabolism"
] | [
"Hydrolase",
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 28: Oligodendrocytes - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,092 | 6 |
ENSG00000105507 | CABP5 | Calcium binding protein 5 | [
"Q9NP86"
] | 19 | 48029383-48044079 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043698"
] | [
"CABP3"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 37 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 1: Neuronal - Visual perception | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in single | 917 | Cancer enhanced | Detected in single | null | Not detected | Not detected | null | Group enriched | Detected in some | 10 | Immune cell enhanced | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 3,093 | 7 |
ENSG00000105516 | DBP | D-box binding PAR bZIP transcription factor | [
"Q10586"
] | 19 | 48630030-48637379 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"DABP"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [] | [] | [] | [] | null | null | null | 4 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 5: Rhabdoid - Unknown function | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 2: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 6 | 0 | 6 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 3,096 | 3 |
ENSG00000105518 | TMEM205 | Transmembrane protein 205 | [
"Q6UW68"
] | 19 | 11342776-11346518 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041504"
] | [
"MBC3205",
"UNQ501"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Endoplasmic reticulum"
] | [
"Nucleoplasm",
"Nuclear membrane"
] | [] | [] | Approved | Approved | null | 25 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 23: Non-specific - Transcription | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,097 | 9 |
ENSG00000105519 | CAPS | Calcyphosine | [
"Q13938"
] | 19 | 5912339-5916211 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043520"
] | [
"CAPS1",
"MGC126562"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Supported | Enhanced | null | 1 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 46: Brainstem - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cancer enriched | Detected in all | 5 | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,098 | 9 |
ENSG00000105520 | PLPPR2 | Phospholipid phosphatase related 2 | [
"Q96GM1"
] | 19 | 11355386-11365698 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048973",
"HPA077966"
] | [
"LPPR2",
"PRG-4"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Uncertain | Approved | null | 33 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 29: Forebrain - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 4 | 1 | 0 | 1 | [] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe"
] | 3,099 | 7 |
ENSG00000105523 | FAM83E | Family with sequence similarity 83 member E | [
"Q2M2I3"
] | 19 | 48599961-48615076 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049305",
"HPA075968"
] | [
"FLJ20200"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Vesicles"
] | [] | [] | Approved | Uncertain | null | 1 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,100 | 9 |
ENSG00000105538 | RASIP1 | Ras interacting protein 1 | [
"Q5U651"
] | 19 | 48720585-48740610 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA077251"
] | [
"FLJ20401",
"RAIN"
] | [
"Predicted intracellular proteins"
] | [
"Angiogenesis"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | null | Cluster 47: Endothelial cells - Vasculature | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 2 | 3 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 3,101 | 6 |
ENSG00000105549 | THEG | Theg spermatid protein | [
"Q9P2T0"
] | 19 | 361747-376026 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA078077"
] | [
"CT56",
"THEG1"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis"
] | [
"Developmental protein"
] | [] | [
"Cytosol",
"Equatorial segment",
"Principal piece",
"Annulus"
] | [] | [] | [] | Approved | null | null | 6 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 21: Lymphoma - Adaptive immune response | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in some | 15 | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,102 | 5 |
ENSG00000105550 | FGF21 | Fibroblast growth factor 21 | [
"Q9NSA1"
] | 19 | 48755524-48758333 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA061286"
] | [] | [
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [] | [
"Growth factor"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Growth factor"
] | null | Supported | null | 6 | null | null | null | null | Cluster 13: Non-specific - Mixed function | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 31: Liver - Metabolism & Coagulation | Tissue enriched | Detected in single | 105 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in single | 361 | Group enriched | Detected in some | 32 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,103 | 5 |
ENSG00000105552 | BCAT2 | Branched chain amino acid transaminase 2 | [
"O15382"
] | 19 | 48795062-48811029 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054091"
] | [
"BCAM",
"BCATm",
"BCT2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Amino-acid biosynthesis",
"Branched-chain amino acid biosynthesis",
"Lipid metabolism"
] | [
"Aminotransferase",
"Transferase"
] | [
"Disease variant"
] | [
"Nucleoplasm",
"Mitochondria"
] | [] | [] | [] | Approved | Enhanced | null | 5 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 42: Choroid plexus - Mitochondria | Cluster 4: Non-specific - Transcription | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 68: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,104 | 8 |
ENSG00000105556 | MIER2 | MIER family member 2 | [
"Q8N344"
] | 19 | 305573-344815 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041439",
"HPA066153"
] | [
"KIAA1193"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Supported | null | 13 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 32: Cerebral cortex - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 3,105 | 2 |
ENSG00000105559 | PLEKHA4 | Pleckstrin homology domain containing A4 | [
"Q9H4M7"
] | 19 | 48837092-48868617 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042978",
"HPA048473"
] | [
"PEPP1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Cytokinetic bridge",
"Centriolar satellite"
] | [] | [] | Approved | Uncertain | null | 5 | Yes | No | null | Cluster 39: Astrocytes - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 103: Non-specific - Basic cellular processes | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Breast Invasive Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 3,106 | 1 |
ENSG00000105568 | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha | [
"P30153"
] | 19 | 52170936-52229518 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB018599"
] | [
"PP2A-Aalpha",
"PP2AA",
"PR65A"
] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Chromosome partition",
"Host-virus interaction"
] | [] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability"
] | [
"Cytosol"
] | [] | [] | [] | Approved | null | null | 271 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 38: Sub-cortical - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,107 | 6 |
ENSG00000105583 | WDR83OS | WD repeat domain 83 opposite strand | [
"Q9Y284"
] | 19 | 12668073-12669415 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065685"
] | [
"Asterix",
"C19orf56",
"PTD008"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Chaperone"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Approved | null | 4 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 27: Non-specific - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Lung Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,109 | 7 |
ENSG00000105605 | CACNG7 | Calcium voltage-gated channel auxiliary subunit gamma 7 | [
"P62955"
] | 19 | 53909278-53943950 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"FDA approved drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calcium channel",
"Ion channel",
"Voltage-gated channel"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | null | null | 13 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in some | 5 | Group enriched | Detected in many | 4 | Cancer enriched | Detected in some | 16 | Cell type enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,110 | 2 |
ENSG00000105607 | GCDH | Glutaryl-CoA dehydrogenase | [
"Q92947"
] | 19 | 12891160-12914207 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043252",
"HPA048492"
] | [
"ACAD5",
"GCD"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [
"Disease variant",
"Glutaricaciduria"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 6 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 13: Oligodendrocytes - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 53: Liver - Plasma proteins | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,111 | 7 |
ENSG00000105609 | LILRB5 | Leukocyte immunoglobulin like receptor B5 | [
"O75023"
] | 19 | 54249421-54257301 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012069"
] | [
"CD85c",
"LIR-8",
"LIR8"
] | [
"CD markers",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Adaptive immunity",
"Immunity"
] | [
"Receptor"
] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 56: Non-specific - Sensory perception | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 5: Spleen - Immune response | Tissue enhanced | Detected in many | null | Not detected | Not detected | null | Low cancer specificity | Detected in some | null | Group enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,112 | 5 |
ENSG00000105610 | KLF1 | KLF transcription factor 1 | [
"Q13351"
] | 19 | 12884422-12887201 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051850"
] | [
"EKLF"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Congenital dyserythropoietic anemia",
"Disease variant",
"Hereditary hemolytic anemia"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 21 | null | null | Cluster 40: Monocytes - Innate immune response | null | Cluster 47: Leukemia - Hemostasis | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in some | 15 | Cancer enriched | Detected in single | 109 | Not detected | Not detected | null | Group enriched | Detected in some | 6 | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 3,113 | 6 |
ENSG00000105612 | DNASE2 | Deoxyribonuclease 2, lysosomal | [
"O00115"
] | 19 | 12875209-12881595 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA066185"
] | [
"DNL",
"DNL2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [
"Developmental protein",
"Endonuclease",
"Hydrolase",
"Nuclease"
] | [
"Disease variant"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Developmental protein"
] | null | Enhanced | null | 1 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 39: Astrocytes - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,114 | 7 |
ENSG00000105613 | MAST1 | Microtubule associated serine/threonine kinase 1 | [
"Q9Y2H9"
] | 19 | 12833951-12874952 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028181",
"HPA073106"
] | [
"KIAA0973",
"SAST"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 17 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 3,115 | 5 |
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