ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000105617 | LENG1 | Leukocyte receptor cluster member 1 | [
"Q96BZ8"
] | 19 | 54155161-54159721 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043541"
] | [] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 76 | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 32: Non-specific - Cell proliferation | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in single | null | Group enriched | Detected in some | 11 | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 3,116 | 2 |
ENSG00000105618 | PRPF31 | Pre-mRNA processing factor 31 | [
"Q8WWY3"
] | 19 | 54115410-54131719 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041939",
"HPA061873"
] | [
"hPrp31",
"NY-BR-99",
"PRP31",
"RP11",
"SNRNP61"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Ribonucleoprotein",
"RNA-binding"
] | [
"Disease variant",
"Retinitis pigmentosa"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 186 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 27: Non-specific - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,117 | 6 |
ENSG00000105619 | TFPT | TCF3 fusion partner | [
"P0C1Z6"
] | 19 | 54107020-54115657 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034958",
"HPA058534"
] | [
"amida",
"FB1",
"INO80F"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"DNA damage",
"DNA recombination",
"DNA repair",
"Transcription",
"Transcription regulation"
] | [] | [
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 85 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 4: Non-specific - Transcription | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 3,118 | 7 |
ENSG00000105640 | RPL18A | Ribosomal protein L18a | [
"Q02543"
] | 19 | 17859910-17864153 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA055259"
] | [
"L18A"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [
"Nucleoli"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Approved | Approved | null | 165 | No | No | Cluster 18: Non-specific - Translation | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 3,120 | 6 |
ENSG00000105641 | SLC5A5 | Solute carrier family 5 member 5 | [
"Q92911"
] | 19 | 17871945-17895174 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022364",
"HPA049055"
] | [
"NIS"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Sodium transport",
"Symport",
"Transport"
] | [] | [
"Congenital hypothyroidism",
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | 4 | null | null | Cluster 31: T-cells - T-cell receptor | Cluster 36: Choroid plexus - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 68: Foveolar cells - Mucosal defense | Cluster 1: Choroid plexus - Transmembrane transport | Group enriched | Detected in some | 7 | Low cancer specificity | Detected in single | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 8 | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 3,121 | 4 |
ENSG00000105642 | KCNN1 | Potassium calcium-activated channel subfamily N member 1 | [
"Q92952"
] | 19 | 17951293-18000085 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA065938"
] | [
"hSK1",
"KCa2.1"
] | [
"FDA approved drug targets",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Transport"
] | [
"Calmodulin-binding",
"Ion channel"
] | [
"FDA approved drug targets"
] | [
"Actin filaments",
"Cytosol"
] | [] | [] | [] | Approved | null | null | 1 | Yes | No | null | Cluster 51: Neurons - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in some | 19 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,122 | 5 |
ENSG00000105643 | ARRDC2 | Arrestin domain containing 2 | [
"Q8TBH0"
] | 19 | 18001132-18014102 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053788",
"HPA074216"
] | [
"CLONE24945",
"PP2703"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 2 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 11: White matter - Signal transduction | Cluster 6: Leukemia - Signal transduction | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,123 | 2 |
ENSG00000105647 | PIK3R2 | Phosphoinositide-3-kinase regulatory subunit 2 | [
"O00459"
] | 19 | 18153163-18170532 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA069291"
] | [
"p85",
"P85B"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Protein transport",
"Stress response",
"Transport"
] | [
"GTPase activation"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Approved | null | 84 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 51: Neurons - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 22: Non-specific - Basic cellular functions | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in some | 16 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,124 | 8 |
ENSG00000105649 | RAB3A | RAB3A, member RAS oncogene family | [
"P20336"
] | 19 | 18196784-18204042 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003160",
"CAB009949",
"CAB078998"
] | [] | [
"Predicted intracellular proteins"
] | [
"Exocytosis",
"Protein transport",
"Transport"
] | [
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [
"Centrosome",
"Cytosol"
] | [] | [] | Approved | Enhanced | Supported | 35 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,125 | 3 |
ENSG00000105650 | PDE4C | Phosphodiesterase 4C | [
"Q08493"
] | 19 | 18207965-18248200 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048975",
"HPA054218"
] | [
"DPDE1"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [
"FDA approved drug targets"
] | [
"Centrosome",
"Basal body",
"Cytosol"
] | [
"Midbody ring"
] | [] | [] | Approved | Approved | null | null | Yes | null | null | Cluster 51: Neurons - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 22: Non-specific - Basic cellular functions | Cluster 62: Skeletal muscle - Muscle contraction | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,126 | 3 |
ENSG00000105655 | ISYNA1 | Inositol-3-phosphate synthase 1 | [
"Q9NPH2"
] | 19 | 18434388-18438167 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007931",
"HPA008232",
"CAB020720"
] | [
"Ino1",
"INOS",
"IPS"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Inositol biosynthesis",
"Lipid biosynthesis",
"Lipid metabolism",
"Phospholipid biosynthesis",
"Phospholipid metabolism"
] | [
"Isomerase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 6 | null | null | Cluster 27: T-cells - Unknown function | Cluster 36: Choroid plexus - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 3,127 | 3 |
ENSG00000105656 | ELL | Elongation factor for RNA polymerase II | [
"P55199"
] | 19 | 18442663-18522116 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004202",
"HPA046076"
] | [
"C19orf17",
"ELL1",
"Men",
"PPP1R68"
] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 31 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 15: Non-specific - Transcription | Cluster 23: Non-specific - Transcription | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 3,128 | 2 |
ENSG00000105662 | CRTC1 | CREB regulated transcription coactivator 1 | [
"Q6UUV9"
] | 19 | 18683678-18782333 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022035",
"HPA063619"
] | [
"FLJ14027",
"KIAA0616",
"MECT1",
"TORC1"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [
"Cancer-related genes"
] | [
"Nuclear bodies",
"Plasma membrane",
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 23 | null | null | Cluster 32: Basophils - Transcription | Cluster 34: Non-specific - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 109: Neurons - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 3,129 | 6 |
ENSG00000105664 | COMP | Cartilage oligomeric matrix protein | [
"P49747"
] | 19 | 18782773-18791305 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA077555"
] | [
"EDM1",
"EPD1",
"MED",
"PSACH",
"THBS5"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Apoptosis",
"Cell adhesion"
] | [
"Heparin-binding"
] | [
"Disease variant",
"Dwarfism"
] | [
"Golgi apparatus"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Cell adhesion"
] | Approved | null | null | 7 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enriched | Detected in many | 4 | Group enriched | Detected in some | 6 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 3,130 | 2 |
ENSG00000105668 | UPK1A | Uroplakin 1A | [
"O00322"
] | 19 | 35666517-35678481 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049879"
] | [
"TSPAN21"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 1 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 11: Esophagus - Basic cellular processes | Tissue enriched | Detected in some | 4 | Cancer enriched | Detected in some | 5 | Cancer enriched | Detected in many | 38 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 3,131 | 9 |
ENSG00000105671 | DDX49 | DEAD-box helicase 49 | [
"Q9Y6V7"
] | 19 | 18919705-18929189 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041870",
"HPA048093"
] | [
"Dbp8",
"FLJ10432"
] | [
"Enzymes",
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [
"Helicase",
"Hydrolase",
"RNA-binding"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Enhanced | null | 10 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 27: Non-specific - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Rectum Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 3,133 | 3 |
ENSG00000105672 | ETV2 | ETS variant transcription factor 2 | [
"O00321"
] | 19 | 35641745-35644871 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [] | [
"ER71"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"DNA-binding"
] | [] | [] | [] | [] | [] | null | null | null | 1 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 35: Non-specific - DNA binding | Cluster 4: Non-specific - Transcription | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 23: Testis - Spermatogenesis | Tissue enriched | Detected in many | 6 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Immune cell enriched | Detected in many | 6 | 2 | 0 | 2 | [
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 3,134 | 4 |
ENSG00000105675 | ATP4A | ATPase H+/K+ transporting subunit alpha | [
"P20648"
] | 19 | 35550031-35563658 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039154",
"HPA076684"
] | [
"ATP6A"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Hydrogen ion transport",
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Translocase"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | 10 | null | null | null | Cluster 2: Neurons - Nucleosome | Cluster 46: Lymphoma - Humoral immune response | Cluster 97: Non-specific - Cellular respiration | Cluster 60: Stomach - Digestion | Tissue enriched | Detected in some | 81 | Not detected | Not detected | null | Cancer enriched | Detected in single | 16 | Cell type enriched | Detected in some | 34 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,135 | 8 |
ENSG00000105676 | ARMC6 | Armadillo repeat containing 6 | [
"Q6NXE6"
] | 19 | 19033575-19060311 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041420",
"HPA041681"
] | [
"MGC19595"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Supported | null | 6 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 1: Neurons - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 31: Liver - Metabolism & Coagulation | Tissue enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 3,136 | 8 |
ENSG00000105677 | TMEM147 | Transmembrane protein 147 | [
"Q9BVK8"
] | 19 | 35545600-35547526 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"MGC1936",
"NIFIE14"
] | [
"Disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Disease variant",
"Intellectual disability"
] | [] | [] | [] | [] | null | null | null | 65 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 21: Non-specific - Metabolism | Cluster 4: Non-specific - Transcription | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,137 | 3 |
ENSG00000105679 | GAPDHS | Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | [
"O14556"
] | 19 | 35533455-35545319 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042666"
] | [
"GAPD2",
"GAPDH-2",
"GAPDS"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Glycolysis"
] | [
"Oxidoreductase"
] | [] | [
"Nucleoplasm",
"Principal piece"
] | [
"Centrosome"
] | [] | [] | Approved | Enhanced | null | 49 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 13: Oligodendrocytes - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in many | 20 | Low cancer specificity | Detected in all | null | Cancer enriched | Detected in many | 18 | Cell type enriched | Detected in many | 6 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,138 | 1 |
ENSG00000105695 | MAG | Myelin associated glycoprotein | [
"P20916"
] | 19 | 35292125-35313807 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009345",
"HPA012499"
] | [
"GMA",
"S-MAG",
"SIGLEC-4A",
"SIGLEC4A"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [
"Disease variant",
"Hereditary spastic paraplegia",
"Neurodegeneration"
] | [
"Equatorial segment",
"Perinuclear theca"
] | [] | [] | [] | Approved | Enhanced | null | 1 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 30: White matter - Myelination | Cluster 69: Skin cancer - ECM organization | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in some | 37 | Cancer enriched | Detected in single | 8 | Cancer enriched | Detected in some | 9 | Cell type enriched | Detected in some | 5 | Immune cell enriched | Detected in single | 12 | 0 | 0 | 0 | [] | [] | [] | 3,139 | 1 |
ENSG00000105696 | TMEM59L | Transmembrane protein 59 like | [
"Q9UK28"
] | 19 | 18607430-18621039 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA010661"
] | [
"BSMAP",
"C19orf4"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 14 | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 5 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 3,140 | 6 |
ENSG00000105697 | HAMP | Hepcidin antimicrobial peptide | [
"P81172"
] | 19 | 35280716-35285143 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"HEPC",
"HFE2B",
"LEAP-1",
"LEAP1"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted secreted proteins",
"Transporters"
] | [] | [
"Antibiotic",
"Antimicrobial",
"Fungicide",
"Hormone"
] | [
"Disease variant"
] | [] | [] | [
"Secreted to blood"
] | [
"Hormone"
] | null | null | null | null | null | null | null | Cluster 12: Non-specific - Vasculature | Cluster 18: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 31: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 5 | Cancer enriched | Detected in some | 5 | Group enriched | Detected in all | 8 | Cell type enriched | Detected in some | 20 | Group enriched | Detected in some | 7 | 3 | 2 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 3,141 | 9 |
ENSG00000105698 | USF2 | Upstream transcription factor 2, c-fos interacting | [
"Q15853"
] | 19 | 35268962-35279821 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029764",
"HPA046567"
] | [
"bHLHb12",
"FIP"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Supported | null | null | 8 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 19: Astrocytes - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 3,142 | 7 |
ENSG00000105699 | LSR | Lipolysis stimulated lipoprotein receptor | [
"Q86X29"
] | 19 | 35248330-35267964 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007270",
"HPA075309"
] | [
"ILDR3",
"LISCH7"
] | [
"Disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [] | [
"Plasma membrane",
"Cell Junctions"
] | [] | [] | [] | Enhanced | Approved | null | 17 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 42: Choroid plexus - Mitochondria | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 3,143 | 6 |
ENSG00000105700 | KXD1 | KxDL motif containing 1 | [
"Q9BQD3"
] | 19 | 18557762-18569387 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041507",
"HPA041599"
] | [
"BORCS4",
"C19orf50",
"FLJ25480",
"KXDL",
"MGC2749"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli fibrillar center",
"Centrosome",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 90 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 13: Oligodendrocytes - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,144 | 2 |
ENSG00000105701 | FKBP8 | FKBP prolyl isomerase 8 | [
"Q14318"
] | 19 | 18531751-18544077 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025346",
"HPA045177"
] | [
"FKBP38",
"FKBPr38"
] | [
"Cancer-related genes",
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis",
"Host-virus interaction"
] | [
"Isomerase",
"Rotamase"
] | [
"Cancer-related genes"
] | [
"Mitochondria"
] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | Supported | Supported | null | 166 | null | null | Cluster 19: Eosinophils - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 23: Non-specific - Transcription | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 78: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Group enriched | Detected in all | 4 | 0 | 0 | 0 | [] | [] | [] | 3,145 | 2 |
ENSG00000105705 | SUGP1 | SURP and G-patch domain containing 1 | [
"Q8IWZ8"
] | 19 | 19276018-19320509 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA004890"
] | [
"DKFZp434E2216",
"F23858",
"RBP",
"SF4"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 37 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 14: Neurons - Synaptic function | Cluster 23: Non-specific - Transcription | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,146 | 4 |
ENSG00000105707 | HPN | Hepsin | [
"P05981"
] | 19 | 35040506-35066573 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA006804"
] | [
"TMPRSS1"
] | [
"Cancer-related genes",
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Approved | null | 4 | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 60: Prostate cancer - Unknown function | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 10 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,147 | 3 |
ENSG00000105708 | ZNF14 | Zinc finger protein 14 | [
"P17017"
] | 19 | 19710472-19733112 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA049863"
] | [
"GIOT-4",
"KOX6"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 6 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 31: Non-specific - Transcription | Cluster 4: Non-specific - Transcription | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 3,148 | 7 |
ENSG00000105711 | SCN1B | Sodium voltage-gated channel beta subunit 1 | [
"Q07699"
] | 19 | 35030470-35040449 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion",
"Ion transport",
"Sodium transport",
"Transport"
] | [] | [
"Atrial fibrillation",
"Brugada syndrome",
"Disease variant",
"Epilepsy",
"FDA approved drug targets"
] | [] | [] | [
"Secreted in other tissues"
] | [
"Transport"
] | null | null | null | 1 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 72: Neuronal - Signal transduction | Cluster 109: Neurons - Neuronal signaling | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,149 | 6 |
ENSG00000105717 | PBX4 | PBX homeobox 4 | [
"Q9BYU1"
] | 19 | 19561707-19618693 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049859",
"HPA056469"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Enhanced | null | 69 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 38: Sub-cortical - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 67: Testis - Mixed function | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in some | null | Cell type enriched | Detected in many | 4 | Group enriched | Detected in many | 7 | 0 | 0 | 0 | [] | [] | [] | 3,150 | 7 |
ENSG00000105722 | ERF | ETS2 repressor factor | [
"P50548"
] | 19 | 42247569-42255128 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA058532",
"HPA067952",
"HPA072144"
] | [
"PE-2",
"PE2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [
"Craniosynostosis",
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Plasma membrane",
"Cytosol"
] | [] | [] | Supported | Approved | null | 27 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 4: Non-specific - Transcription | Cluster 103: Non-specific - Basic cellular processes | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,151 | 1 |
ENSG00000105723 | GSK3A | Glycogen synthase kinase 3 alpha | [
"P49840"
] | 19 | 42226225-42242625 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004422",
"HPA006495",
"HPA028423"
] | [] | [
"Cancer-related genes",
"Enzymes",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism",
"Glycogen metabolism",
"Neurogenesis",
"Wnt signaling pathway"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Signal transduction inhibitor",
"Transferase"
] | [
"Alzheimer disease",
"Cancer-related genes",
"Diabetes mellitus"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 88 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 4: Non-specific - Transcription | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 3,152 | 7 |
ENSG00000105726 | ATP13A1 | ATPase 13A1 | [
"Q9HD20"
] | 19 | 19645198-19663676 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031798",
"HPA049717"
] | [
"ATP13A",
"CGI-152",
"FLJ31858",
"KIAA1825"
] | [
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [
"Translocase"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 13 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 36: Choroid plexus - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 3,153 | 1 |
ENSG00000105732 | ZNF574 | Zinc finger protein 574 | [
"Q6ZN55"
] | 19 | 42068477-42081552 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA023196",
"HPA057274"
] | [
"FLJ22059"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 15: Non-specific - Transcription | Cluster 4: Non-specific - Transcription | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 3,154 | 1 |
ENSG00000105737 | GRIK5 | Glutamate ionotropic receptor kainate type subunit 5 | [
"Q16478"
] | 19 | 41998321-42070206 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA074001"
] | [
"GluK5",
"GRIK2",
"KA2"
] | [
"FDA approved drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Supported | null | null | 2 | null | null | null | Cluster 29: Forebrain - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 65: Brain - Transcription | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 6 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 3,155 | 5 |
ENSG00000105738 | SIPA1L3 | Signal induced proliferation associated 1 like 3 | [
"O60292"
] | 19 | 37907208-38208369 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042072",
"HPA045480",
"HPA074988"
] | [
"KIAA0545",
"SPAR3"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [
"Cataract"
] | [
"Plasma membrane"
] | [
"Nucleoplasm",
"Golgi apparatus"
] | [] | [] | Supported | Uncertain | null | 26 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 29: Forebrain - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 3,156 | 5 |
ENSG00000105750 | ZNF85 | Zinc finger protein 85 | [
"Q03923"
] | 19 | 20923222-20950697 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044760"
] | [
"HPF4",
"HTF1"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | null | null | null | Cluster 24: Non-specific - Transcription | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 4: Non-specific - Transcription | Cluster 102: Non-specific - Mixed function | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma",
"Uterine Corpus Endometrial Carcinoma"
] | 3,157 | 2 |
ENSG00000105755 | ETHE1 | ETHE1 persulfide dioxygenase | [
"O95571"
] | 19 | 43506719-43527230 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028360",
"HPA029028",
"HPA029029"
] | [
"HSCO",
"YF13H12"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Dioxygenase",
"Oxidoreductase"
] | [
"Disease variant"
] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Enhanced | null | 5 | No | No | Cluster 13: Non-specific - Mitochondria | Cluster 19: Astrocytes - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 3,158 | 6 |
ENSG00000105767 | CADM4 | Cell adhesion molecule 4 | [
"Q8NFZ8"
] | 19 | 43622368-43639850 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012612",
"HPA070705"
] | [
"IGSF4C",
"Necl-4",
"SynCAM4",
"TSLL2"
] | [
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [
"Tumor suppressor"
] | [
"Plasma membrane"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 10 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 7 | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 3,159 | 2 |
ENSG00000105771 | SMG9 | SMG9 nonsense mediated mRNA decay factor | [
"Q9H0W8"
] | 19 | 43727983-43754962 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041763",
"HPA042096",
"HPA066150"
] | [
"C19orf61",
"FLJ12886"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Nonsense-mediated mRNA decay"
] | [] | [
"Intellectual disability"
] | [
"Cytosol"
] | [
"Vesicles"
] | [] | [] | Approved | Uncertain | null | 36 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 4: Non-specific - Transcription | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,160 | 9 |
ENSG00000105784 | RUNDC3B | RUN domain containing 3B | [
"Q96NL0"
] | 7 | 87627548-87832296 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA056968",
"HPA057155"
] | [
"RPIB9",
"RPIP9"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Intermediate filaments"
] | [
"Cytokinetic bridge",
"Primary cilium",
"Centrosome",
"Basal body",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 4 | Yes | null | null | Cluster 1: Neurons - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 104: Brain endothelial cells - Blood brain barrier | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Not detected | Not detected | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,162 | 9 |
ENSG00000105792 | CFAP69 | Cilia and flagella associated protein 69 | [
"A5D8W1"
] | 7 | 90245174-90311063 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA062883"
] | [
"C7orf63",
"FAP69",
"FLJ21062"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Olfaction",
"Sensory transduction",
"Spermatogenesis"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | Cluster 17: Choroid plexus - Cilium | Cluster 60: Prostate cancer - Unknown function | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,163 | 7 |
ENSG00000105793 | GTPBP10 | GTP binding protein 10 | [
"A4D1E9"
] | 7 | 90335223-90391453 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA021076"
] | [
"DKFZP686A10121",
"FLJ38242",
"OBGH2"
] | [
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 28 | null | null | Cluster 39: T-cells - T-cell receptor | Cluster 16: Non-specific - Transcription | Cluster 39: Non-specific - Transcription | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,164 | 3 |
ENSG00000105808 | RASA4 | RAS p21 protein activator 4 | [
"O43374"
] | 7 | 102579646-102616756 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA043010"
] | [
"CAPRI",
"GAPL",
"KIAA0538"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Vesicles"
] | [
"Cell Junctions"
] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 64: Connective tissue cells - ECM organization | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 19: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 3,165 | 5 |
ENSG00000105819 | PMPCB | Peptidase, mitochondrial processing subunit beta | [
"O75439"
] | 7 | 103297407-103331818 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040674",
"HPA074168"
] | [
"beta-MPP",
"MAS1",
"MPPB",
"MPPP52"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Disease variant",
"Neurodegeneration"
] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Approved | null | 34 | No | No | Cluster 12: Non-specific - Mitochondrial translation | Cluster 21: Non-specific - Metabolism | Cluster 39: Non-specific - Transcription | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,167 | 4 |
ENSG00000105825 | TFPI2 | Tissue factor pathway inhibitor 2 | [
"P48307"
] | 7 | 93885396-93890753 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010142",
"HPA049158",
"HPA070525"
] | [
"PP5",
"REF1",
"TFPI-2"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Blood coagulation",
"Hemostasis"
] | [
"Protease inhibitor",
"Serine protease inhibitor"
] | [] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Blood coagulation"
] | null | Enhanced | null | null | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func. | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enriched | Detected in many | 12 | Cancer enhanced | Detected in all | null | Group enriched | Detected in all | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Breast Invasive Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,169 | 3 |
ENSG00000105829 | BET1 | Bet1 golgi vesicular membrane trafficking protein | [
"O15155"
] | 7 | 93962762-94004382 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"hbet1"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [] | [
"Congenital muscular dystrophy"
] | [] | [] | [] | [] | null | null | null | 92 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 21: Non-specific - Metabolism | Cluster 39: Non-specific - Transcription | Cluster 8: Non-specific - Secretory pathway | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | 3,170 | 2 |
ENSG00000105851 | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | [
"P48736"
] | 7 | 106865278-106908980 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA069976"
] | [] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Angiogenesis",
"Chemotaxis",
"Endocytosis",
"Immunity",
"Inflammatory response",
"Lipid metabolism"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 10 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 20: Macrophages & Microglia - Immune response | Cluster 46: Lymphoma - Humoral immune response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 44: Bone marrow - Nuclear processes | Group enriched | Detected in many | 6 | Group enriched | Detected in some | 14 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 3,173 | 8 |
ENSG00000105852 | PON3 | Paraoxonase 3 | [
"Q15166"
] | 7 | 95359872-95396375 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014848",
"CAB025250"
] | [] | [
"Candidate cardiovascular disease genes",
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Enhanced | null | 1 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 7: Liver cancer - Metabolism | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 20 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 7 | Cell type enriched | Detected in many | 9 | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,174 | 3 |
ENSG00000105854 | PON2 | Paraoxonase 2 | [
"Q15165"
] | 7 | 95404862-95435329 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025430",
"HPA029193"
] | [] | [
"Candidate cardiovascular disease genes",
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Enhanced | null | 11 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 39: Astrocytes - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 2 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 3,175 | 2 |
ENSG00000105855 | ITGB8 | Integrin subunit beta 8 | [
"P26012"
] | 7 | 20330702-20415754 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027796",
"HPA027797"
] | [] | [
"Cancer-related genes",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [
"Integrin",
"Receptor"
] | [
"Cancer-related genes"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 7 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 39: Astrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 134 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 3,176 | 3 |
ENSG00000105856 | HBP1 | HMG-box transcription factor 1 | [
"O60381"
] | 7 | 107168961-107202522 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020225",
"CAB032824"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation",
"Wnt signaling pathway"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Approved | null | 11 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 13: Oligodendrocytes - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,177 | 1 |
ENSG00000105865 | DUS4L | Dihydrouridine synthase 4 like | [
"O95620"
] | 7 | 107563484-107578523 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044301"
] | [
"DUS4",
"PP35"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [
"Oxidoreductase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | null | null | null | null | Cluster 28: Oligodendrocytes - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 102: Non-specific - Mixed function | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 3,178 | 5 |
ENSG00000105866 | SP4 | Sp4 transcription factor | [
"Q02446"
] | 7 | 21428043-21514822 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010246",
"HPA040395"
] | [
"HF1B",
"MGC130008",
"MGC130009",
"SPR-1"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | Uncertain | null | 21 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 67: Non-specific - Unknown function | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,179 | 6 |
ENSG00000105875 | WDR91 | WD repeat domain 91 | [
"A4D1P6"
] | 7 | 135183839-135211555 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024260"
] | [
"HSPC049",
"SORF-1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 3 | null | null | Cluster 18: Non-specific - Translation | Cluster 36: Choroid plexus - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,180 | 7 |
ENSG00000105877 | DNAH11 | Dynein axonemal heavy chain 11 | [
"Q96DT5"
] | 7 | 21543039-21901839 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045880",
"HPA056474"
] | [
"CILD7",
"DNAHBL",
"Dnahc11",
"DNHBL",
"DPL11"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Motor protein"
] | [
"Ciliopathy",
"Disease variant",
"Kartagener syndrome",
"Primary ciliary dyskinesia"
] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | null | Cluster 3: Choroid plexus - Cilium | Cluster 15: Kidney cancer - Membrane components | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 69: Parathyroid gland - Mixed function | Tissue enriched | Detected in some | 10 | Low cancer specificity | Detected in some | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,181 | 4 |
ENSG00000105879 | CBLL1 | Cbl proto-oncogene like 1 | [
"Q75N03"
] | 7 | 107743073-107761667 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021773",
"HPA026699"
] | [
"FLJ23109",
"HAKAI",
"RNF188"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Developmental protein",
"Transferase"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Enhanced | null | 10 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 31: Non-specific - Transcription | Cluster 39: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,182 | 8 |
ENSG00000105880 | DLX5 | Distal-less homeobox 5 | [
"P56178"
] | 7 | 97020396-97024950 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA005670"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Osteogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [
"Deafness",
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 10: Ciliated cells - Ion channel activity | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 37: Skin - Keratinization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in many | 6 | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,183 | 8 |
ENSG00000105887 | MTPN | Myotrophin | [
"P58546"
] | 7 | 135926760-135977359 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019735"
] | [
"GCDP",
"MYOTROPHIN",
"V-1"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 9 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 33: Neurons - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 47: Platelets - Hemostasis | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 6 | 0 | 6 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 3,184 | 3 |
ENSG00000105889 | STEAP1B | STEAP family member 1B | [
"Q6NZ63"
] | 7 | 22419444-22727613 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | 3 | null | null | Cluster 34: B-cells - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 15: Non-specific - Protein processing | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 67 | 2 | 0 | 2 | [] | [
"Bladder Urothelial Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 3,185 | 6 |
ENSG00000105894 | PTN | Pleiotrophin | [
"P21246"
] | 7 | 137227341-137343774 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017685",
"HPA073913"
] | [
"HBGF8",
"HBNF",
"NEGF1"
] | [
"Cancer-related genes",
"Predicted secreted proteins"
] | [] | [
"Growth factor",
"Heparin-binding",
"Mitogen"
] | [
"Cancer-related genes"
] | [
"Endoplasmic reticulum"
] | [] | [
"Secreted to blood"
] | [
"Growth factor"
] | Supported | Enhanced | null | 22 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 72: Neuronal - Signal transduction | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in all | 12 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 3,186 | 2 |
ENSG00000105926 | PALS2 | Protein associated with LIN7 2, MAGUK p55 family member | [
"Q9NZW5"
] | 7 | 24573268-24694193 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019085",
"HPA020456"
] | [
"MPP6",
"p55T",
"VAM-1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 17 | null | null | Cluster 24: Non-specific - Transcription | Cluster 29: Forebrain - Mixed function | Cluster 67: Non-specific - Unknown function | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 67: Testis - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,187 | 9 |
ENSG00000105928 | GSDME | Gasdermin E | [
"O60443"
] | 7 | 24698355-24757940 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011326",
"CAB019306"
] | [
"DFNA5",
"ICERE-1"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Necrosis"
] | [] | [
"Deafness",
"Non-syndromic deafness",
"Tumor suppressor"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 9 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 4 | 3 | 0 | 3 | [] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Stomach Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Stomach Adenocarcinoma"
] | 3,188 | 5 |
ENSG00000105929 | ATP6V0A4 | ATPase H+ transporting V0 subunit a4 | [
"Q9HBG4"
] | 7 | 138706294-138799560 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018029",
"HPA064555"
] | [
"a4",
"ATP6N1B",
"ATP6N2",
"RDRTA2",
"RTA1C",
"RTADR",
"Stv1",
"Vph1",
"VPP2"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Hydrogen ion transport",
"Ion transport",
"Transport"
] | [] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Uncertain | Enhanced | null | 22 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 70: DU4475 - Unknown function | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 72: Kidney - Transmembrane transport | Group enriched | Detected in some | 7 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 28 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Bladder Urothelial Carcinoma"
] | [
"Bladder Urothelial Carcinoma"
] | 3,189 | 7 |
ENSG00000105939 | ZC3HAV1 | Zinc finger CCCH-type containing, antiviral 1 | [
"Q7Z2W4"
] | 7 | 139043515-139132122 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047818",
"HPA059096"
] | [
"ARTD13",
"FLB6421",
"FLJ13288",
"MGC48898",
"PARP13",
"ZAP",
"ZC3H2",
"ZC3HDC2"
] | [
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"Immunity",
"Innate immunity"
] | [
"RNA-binding"
] | [] | [
"Cytosol"
] | [
"Golgi apparatus"
] | [] | [] | Supported | Approved | null | 163 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 12: Non-specific - Vasculature | Cluster 31: Non-specific - Antiviral immune response | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,190 | 5 |
ENSG00000105948 | TTC26 | Tetratricopeptide repeat domain 26 | [
"A0AVF1"
] | 7 | 139133744-139191986 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036338",
"HPA061867"
] | [
"dyf-13",
"DYF13",
"FLJ12571",
"IFT56"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [
"Ciliopathy",
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Primary cilium",
"Mitochondria",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 51 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 17: Choroid plexus - Cilium | Cluster 39: Non-specific - Transcription | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 3,191 | 4 |
ENSG00000105954 | NPVF | Neuropeptide VF precursor | [
"Q9HCQ7"
] | 7 | 25224570-25228486 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041733"
] | [
"C7orf9",
"RFRP"
] | [
"Predicted secreted proteins"
] | [] | [
"Neuropeptide"
] | [] | [] | [] | [
"Secreted in other tissues"
] | [
"Neuropeptide"
] | null | Enhanced | null | 2 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 65: Non-specific - Unknown function | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in some | 41 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 125 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,193 | 8 |
ENSG00000105963 | ADAP1 | ArfGAP with dual PH domains 1 | [
"O75689"
] | 7 | 897900-955407 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007033",
"HPA012049"
] | [
"CENTA1",
"GCS1L"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 12 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 30: White matter - Myelination | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 3,194 | 7 |
ENSG00000105967 | TFEC | Transcription factor EC | [
"O14948"
] | 7 | 115935148-116159896 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB032260",
"HPA050528",
"HPA063577"
] | [
"bHLHe34",
"TCFEC",
"TFECL"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 3 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 55: Lymphoma - Immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 13 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 10 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,195 | 2 |
ENSG00000105968 | H2AZ2 | H2A.Z variant histone 2 | [
"Q71UI9"
] | 7 | 44826791-44848087 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA057236"
] | [
"H2AFV",
"H2AV",
"MGC10170",
"MGC10831",
"MGC1947"
] | [
"Predicted intracellular proteins"
] | [] | [
"DNA-binding"
] | [] | [] | [] | [] | [] | null | Supported | null | 8 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 13: Oligodendrocytes - Mixed function | Cluster 67: Non-specific - Unknown function | Cluster 27: Non-specific - Cell proliferation | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,196 | 1 |
ENSG00000105974 | CAV1 | Caveolin 1 | [
"Q03135"
] | 7 | 116524994-116561179 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB003791",
"HPA049326",
"HPA059079"
] | [
"CAV"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Host-virus interaction"
] | [] | [
"Cancer-related genes",
"Congenital generalized lipodystrophy",
"Diabetes mellitus",
"Disease variant"
] | [
"Golgi apparatus"
] | [
"Perinuclear theca",
"Connecting piece",
"Principal piece"
] | [] | [] | Supported | Enhanced | null | 126 | null | null | Cluster 17: B-cells - Immunoglobulins | Cluster 47: Endothelial cells - Vasculature | Cluster 39: Non-specific - Transcription | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 10 | 3 | 0 | 3 | [] | [
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 3,198 | 3 |
ENSG00000105976 | MET | MET proto-oncogene, receptor tyrosine kinase | [
"P08581"
] | 7 | 116672196-116798377 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005282",
"HPA055607"
] | [
"DFNB97",
"HGFR",
"RCCP2"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins",
"RAS pathway related proteins",
"Transporters"
] | [] | [
"Kinase",
"Receptor",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes",
"Deafness",
"Disease variant",
"FDA approved drug targets",
"Non-syndromic deafness",
"Proto-oncogene"
] | [
"Plasma membrane"
] | [
"Cytosol"
] | [
"Secreted to blood"
] | [
"Receptor"
] | Approved | Approved | null | 77 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,199 | 5 |
ENSG00000105982 | RNF32 | Ring finger protein 32 | [
"Q9H0A6"
] | 7 | 156640281-156677130 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019516",
"HPA073560"
] | [
"FKSG33",
"HSD15",
"LMBR2"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nuclear bodies",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 10 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 28: Oligodendrocytes - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 4 | Immune cell enriched | Detected in many | 5 | 2 | 0 | 2 | [] | [
"Colon Adenocarcinoma",
"Thyroid Carcinoma"
] | [
"Colon Adenocarcinoma",
"Thyroid Carcinoma"
] | 3,200 | 7 |
ENSG00000105983 | LMBR1 | Limb development membrane protein 1 | [
"Q8WVP7"
] | 7 | 156668946-156893216 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA016592"
] | [
"ACHP",
"C7orf2",
"FLJ11665",
"ZRS"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 39: Non-specific - Transcription | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 3,201 | 7 |
ENSG00000105989 | WNT2 | Wnt family member 2 | [
"P09544"
] | 7 | 117275451-117323152 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA020920"
] | [
"INT1L1",
"IRP"
] | [
"Cancer-related genes",
"Predicted secreted proteins"
] | [
"Wnt signaling pathway"
] | [
"Developmental protein"
] | [
"Cancer-related genes"
] | [
"Vesicles"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Developmental protein"
] | Approved | null | null | 7 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enriched | Detected in some | 5 | Cancer enhanced | Detected in single | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in some | 12 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,202 | 1 |
ENSG00000105991 | HOXA1 | Homeobox A1 | [] | 7 | 27092993-27096000 | Evidence at transcript level | Evidence at transcript level | null | null | [] | [
"HOX1",
"HOX1F"
] | [
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | 18 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 43: Hindbrain - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 95: Tuft cells - Chemosensory signaling | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in some | 4 | Group enriched | Detected in some | 6 | 2 | 0 | 2 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | 3,203 | 8 |
ENSG00000105996 | HOXA2 | Homeobox A2 | [
"O43364"
] | 7 | 27100354-27102686 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA078220"
] | [
"HOX1K"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Disease variant"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Approved | null | null | 1 | Yes | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 15: Non-specific - Protein processing | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 3,205 | 5 |
ENSG00000105997 | HOXA3 | Homeobox A3 | [
"O43365"
] | 7 | 27106184-27152583 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029157"
] | [
"HOX1",
"HOX1E"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 2 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 4 | 0 | 4 | [
"Breast Invasive Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 3,206 | 2 |
ENSG00000106003 | LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | [
"Q8NES3"
] | 7 | 2512529-2529177 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA069130"
] | [
"SCDO3"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Developmental protein",
"Glycosyltransferase",
"Transferase"
] | [
"Disease variant",
"Dwarfism"
] | [
"Nuclear membrane",
"Golgi apparatus"
] | [] | [
"Intracellular and membrane"
] | [
"Developmental protein"
] | Approved | Approved | null | null | null | null | Cluster 25: Non-specific - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 8: Pancreas - Proteolysis | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 3,207 | 6 |
ENSG00000106004 | HOXA5 | Homeobox A5 | [
"P20719"
] | 7 | 27141052-27143681 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"HOX1",
"HOX1C"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | null | null | 10 | null | null | Cluster 32: Basophils - Transcription | Cluster 43: Hindbrain - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 108: Fibroblasts - ECM organization | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Rectum Adenocarcinoma"
] | [
"Rectum Adenocarcinoma"
] | 3,208 | 2 |
ENSG00000106006 | HOXA6 | Homeobox A6 | [
"P31267"
] | 7 | 27145396-27150603 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA004203",
"HPA077900"
] | [
"HOX1",
"HOX1B"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear speckles"
] | [] | [] | Supported | Approved | null | null | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 3,209 | 6 |
ENSG00000106009 | BRAT1 | BRCA1 associated ATM activator 1 | [
"Q6PJG6"
] | 7 | 2537810-2555694 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029455",
"HPA076508"
] | [
"BAAT1",
"C7orf27",
"MGC22916"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"DNA damage"
] | [] | [
"Disease variant",
"Epilepsy"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 33 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 27: Non-specific - Mixed function | Cluster 67: Non-specific - Unknown function | Cluster 65: Non-specific - Cell growth & division | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,210 | 2 |
ENSG00000106012 | IQCE | IQ motif containing E | [
"Q6IPM2"
] | 7 | 2558972-2614733 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019515"
] | [
"KIAA1023"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Plasma membrane"
] | [
"Nuclear membrane",
"Primary cilium"
] | [] | [] | Approved | Approved | null | 9 | Yes | No | Cluster 21: Neutrophils - Unknown function | Cluster 17: Choroid plexus - Cilium | Cluster 67: Non-specific - Unknown function | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,211 | 2 |
ENSG00000106013 | ANKRD7 | Ankyrin repeat domain 7 | [
"Q92527"
] | 7 | 118214669-118496171 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA043489",
"HPA052941"
] | [
"TSA806"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | null | null | null | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in some | 426 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,212 | 3 |
ENSG00000106018 | VIPR2 | Vasoactive intestinal peptide receptor 2 | [
"P41587"
] | 7 | 159028175-159144867 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA062707"
] | [
"VPAC2",
"VPAC2R"
] | [
"G-protein coupled receptors",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [
"Focal adhesion sites"
] | [] | [] | [] | Approved | Approved | null | null | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 17 | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme"
] | 3,213 | 7 |
ENSG00000106025 | TSPAN12 | Tetraspanin 12 | [
"O95859"
] | 7 | 120787320-120858402 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051570",
"HPA058244"
] | [
"NET-2",
"TM4SF12"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Angiogenesis"
] | [] | [
"Disease variant"
] | [
"Microtubules"
] | [
"Vesicles"
] | [] | [] | Approved | Uncertain | null | 23 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,214 | 5 |
ENSG00000106028 | SSBP1 | Single stranded DNA binding protein 1 | [
"Q04837"
] | 7 | 141738334-141787922 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002866"
] | [
"mtSSB",
"SSBP"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"DNA replication"
] | [
"DNA-binding"
] | [
"Disease variant"
] | [
"Mitochondria"
] | [
"Calyx",
"Principal piece"
] | [] | [] | Supported | Supported | null | 73 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 28: Oligodendrocytes - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 3,215 | 6 |
ENSG00000106034 | CPED1 | Cadherin like and PC-esterase domain containing 1 | [
"A4D0V7"
] | 7 | 120988697-121297442 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA012058"
] | [
"C7orf58",
"FLJ21986"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 64: Connective tissue cells - ECM organization | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Group enriched | Detected in many | 7 | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 3,217 | 8 |
ENSG00000106038 | EVX1 | Even-skipped homeobox 1 | [
"P49640"
] | 7 | 27242700-27250493 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA055132"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | null | null | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in some | null | Group enriched | Detected in some | 4 | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,218 | 8 |
ENSG00000106052 | TAX1BP1 | Tax1 binding protein 1 | [
"Q86VP1"
] | 7 | 27739331-27844564 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024432"
] | [
"CALCOCO3",
"TXBP151"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis",
"Autophagy",
"Host-virus interaction",
"Immunity",
"Innate immunity"
] | [] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 103 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 21: Non-specific - Metabolism | Cluster 67: Non-specific - Unknown function | Cluster 84: Apical squamous epithelium - Cornification | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Chromophobe"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 3,220 | 8 |
ENSG00000106066 | CPVL | Carboxypeptidase vitellogenic like | [
"Q9H3G5"
] | 7 | 28995235-29195451 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB003697",
"HPA045715",
"HPA056466"
] | [] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Carboxypeptidase",
"Hydrolase",
"Protease"
] | [] | [
"Endoplasmic reticulum"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Approved | Enhanced | null | 39 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 25: Non-specific - Transcription | Cluster 15: Kidney cancer - Membrane components | Cluster 82: Dendritic cells - Antigen presentation | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 3,221 | 2 |
ENSG00000106069 | CHN2 | Chimerin 2 | [
"P52757"
] | 7 | 29146547-29514328 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018989",
"HPA019026"
] | [
"ARHGAP3",
"RhoGAP3"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Approved | Approved | null | 9 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 25: Non-specific - Transcription | Cluster 1: Neuronal - Visual perception | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Pancreatic Adenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 3,222 | 4 |
ENSG00000106070 | GRB10 | Growth factor receptor bound protein 10 | [
"Q13322"
] | 7 | 50590063-50793462 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB019423",
"HPA027502",
"HPA031818"
] | [] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes"
] | [
"Vesicles"
] | [] | [] | [] | Supported | Enhanced | null | 37 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 67: Non-specific - Unknown function | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 13 | 4 | 4 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 3,223 | 9 |
ENSG00000106077 | ABHD11 | Abhydrolase domain containing 11 | [
"Q8NFV4"
] | 7 | 73736094-73738852 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024042",
"HPA049641"
] | [
"PP1226",
"WBSCR21"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [
"Williams-Beuren syndrome"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Approved | null | null | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 44: Non-specific - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 3,224 | 9 |
ENSG00000106078 | COBL | Cordon-bleu WH2 repeat protein | [
"O75128"
] | 7 | 51016212-51316818 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019033",
"HPA019167"
] | [
"KIAA0633"
] | [
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [
"Plasma membrane",
"Cell Junctions"
] | [] | [] | [] | Approved | Enhanced | null | 14 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 11: White matter - Signal transduction | Cluster 15: Kidney cancer - Membrane components | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 14 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,225 | 5 |
ENSG00000106086 | PLEKHA8 | Pleckstrin homology domain containing A8 | [
"Q96JA3"
] | 7 | 30027404-30130483 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA072314"
] | [
"FAPP2",
"MGC3358"
] | [
"Predicted intracellular proteins"
] | [
"Lipid transport",
"Protein transport",
"Transport"
] | [] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm"
] | [] | [] | Uncertain | null | null | 1 | null | null | null | Cluster 31: Non-specific - Transcription | Cluster 67: Non-specific - Unknown function | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 42: Retina - Visual perception | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,227 | 8 |
ENSG00000106089 | STX1A | Syntaxin 1A | [
"Q16623"
] | 7 | 73699206-73719672 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB008372",
"HPA069176"
] | [
"HPC-1",
"p35-1",
"STX1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Exocytosis",
"Neurotransmitter transport",
"Transport"
] | [] | [
"Williams-Beuren syndrome"
] | [
"Vesicles"
] | [
"Nuclear membrane"
] | [
"Intracellular and membrane"
] | [
"Transport"
] | Approved | Enhanced | null | 130 | null | null | Cluster 16: Non-specific - Cell proliferation | Cluster 53: Neurons - Mixed function | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 10: Brain - Synaptic signal transduction | Group enriched | Detected in many | 12 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 5 | 2 | 4 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma",
"Thyroid Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma",
"Thyroid Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 3,228 | 3 |
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