ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000106100 | NOD1 | Nucleotide binding oligomerization domain containing 1 | [
"Q9Y239"
] | 7 | 30424527-30478784 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA074367"
] | [
"CARD4",
"CLR7.1",
"NLRC1"
] | [
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Immunity",
"Innate immunity"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | null | null | 21 | null | null | Cluster 32: Basophils - Transcription | Cluster 20: Macrophages & Microglia - Immune response | Cluster 67: Non-specific - Unknown function | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 3,229 | 3 |
ENSG00000106105 | GARS1 | Glycyl-tRNA synthetase 1 | [
"P41250"
] | 7 | 30580533-30634033 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017896",
"HPA019097"
] | [
"CMT2D",
"DSMAV",
"GARS",
"GlyRS",
"SMAD1"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Aminoacyl-tRNA synthetase",
"Hydrolase",
"Ligase",
"Transferase"
] | [
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Cytosol"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Supported | Enhanced | null | 35 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 23: Choroid plexus - Mixed function | Cluster 13: Non-specific - Mixed function | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,230 | 8 |
ENSG00000106113 | CRHR2 | Corticotropin releasing hormone receptor 2 | [
"Q13324"
] | 7 | 30651942-30700129 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA073345"
] | [
"CRF-RB",
"CRF2",
"HM-CRF"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [
"Plasma membrane"
] | [] | [
"Secreted - unknown location"
] | [
"Receptor"
] | Supported | null | null | null | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enriched | Detected in some | 5 | Cancer enriched | Detected in single | 6 | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,231 | 2 |
ENSG00000106123 | EPHB6 | EPH receptor B6 | [] | 7 | 142855061-142871094 | Evidence at transcript level | Evidence at transcript level | null | null | [
"HPA035784"
] | [
"HEP"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nuclear speckles"
] | [] | [
"Intracellular and membrane"
] | [] | Uncertain | null | null | 5 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 53: Neurons - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 2: Non-specific - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,232 | 9 |
ENSG00000106125 | MINDY4 | MINDY lysine 48 deubiquitinase 4 | [
"Q4G0A6"
] | 7 | 30771417-30892387 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019475",
"HPA030129",
"HPA030130"
] | [
"C7orf67",
"FAM188B",
"FLJ22374"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 2 | null | null | null | Cluster 17: Choroid plexus - Cilium | Cluster 67: Non-specific - Unknown function | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 56: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,233 | 6 |
ENSG00000106128 | GHRHR | Growth hormone releasing hormone receptor | [
"Q02643"
] | 7 | 30938669-30993254 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Disease related genes",
"FDA approved drug targets",
"G-protein coupled receptors",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"Disease variant",
"Dwarfism",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | null | null | null | null | null | null | null | Cluster 60: Prostate cancer - Unknown function | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 20: Pituitary gland - Hormone signaling | Tissue enriched | Detected in single | 354 | Cancer enriched | Detected in single | 10 | Not detected | Not detected | null | Cell type enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,234 | 4 |
ENSG00000106144 | CASP2 | Caspase 2 | [
"P42575"
] | 7 | 143288215-143307696 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006938",
"CAB012175",
"HPA050678"
] | [
"ICH1",
"MGC2181",
"NEDD2",
"PPP1R57"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability",
"Lissencephaly"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Approved | null | 16 | null | Yes | Cluster 5: Non-specific - Cell proliferation | Cluster 11: White matter - Signal transduction | Cluster 39: Non-specific - Transcription | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,235 | 1 |
ENSG00000106153 | CHCHD2 | Coiled-coil-helix-coiled-coil-helix domain containing 2 | [
"Q9Y6H1"
] | 7 | 56101573-56106476 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027407",
"HPA052510"
] | [
"C7orf17",
"MIX17B",
"MNRR1"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Transcription"
] | [
"Activator"
] | [
"Neurodegeneration",
"Parkinson disease",
"Parkinsonism"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Approved | null | 66 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 67: Non-specific - Unknown function | Cluster 97: Non-specific - Cellular respiration | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,236 | 3 |
ENSG00000106178 | CCL24 | C-C motif chemokine ligand 24 | [
"O00175"
] | 7 | 75810825-75823356 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"Ckb-6",
"eotaxin-2",
"MPIF-2",
"MPIF2",
"SCYA24"
] | [
"Predicted secreted proteins"
] | [
"Chemotaxis",
"Inflammatory response"
] | [
"Cytokine"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Chemokine"
] | null | null | null | 1 | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 5: Spleen - Immune response | Group enriched | Detected in some | 5 | Cancer enriched | Detected in some | 9 | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,237 | 3 |
ENSG00000106211 | HSPB1 | Heat shock protein family B (small) member 1 | [
"P04792"
] | 7 | 76302673-76304295 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000497",
"CAB004439",
"CAB047330",
"CAB047331",
"CAB047332"
] | [
"CMT2F",
"Hs.76067",
"Hsp25",
"HSP27",
"HSP28"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Stress response"
] | [
"Chaperone"
] | [
"Cancer-related genes",
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 281 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 39: Astrocytes - Mixed function | Cluster 35: RS4;11 - Unknown function | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 3,238 | 8 |
ENSG00000106236 | NPTX2 | Neuronal pentraxin 2 | [
"P47972"
] | 7 | 98617285-98629869 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB020801",
"HPA049799",
"HPA058320"
] | [] | [
"Predicted secreted proteins"
] | [] | [] | [] | [
"Golgi apparatus",
"Actin filaments"
] | [
"Centrosome"
] | [
"Secreted to blood"
] | [
"No annotated function"
] | Approved | Enhanced | null | 9 | null | null | null | Cluster 29: Forebrain - Mixed function | Cluster 54: Non-specific - Transcription | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 20: Pituitary gland - Hormone signaling | Tissue enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 3,239 | 9 |
ENSG00000106244 | PDAP1 | PDGFA associated protein 1 | [
"Q13442"
] | 7 | 99392048-99408597 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB021103",
"HPA050294",
"HPA060836"
] | [
"HASPP28",
"PAP",
"PAP1"
] | [
"Cancer-related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Enhanced | Approved | null | 9 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 45: Non-specific - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,240 | 6 |
ENSG00000106246 | PTCD1 | Pentatricopeptide repeat domain 1 | [
"O75127"
] | 7 | 99416739-99466163 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020106",
"HPA047679"
] | [
"KIAA0632"
] | [
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Uncertain | null | 46 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 6: Non-specific - Immune response | Cluster 39: Non-specific - Transcription | Cluster 22: Non-specific - Basic cellular functions | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 3,242 | 5 |
ENSG00000106258 | CYP3A5 | Cytochrome P450 family 3 subfamily A member 5 | [
"P20815"
] | 7 | 99648194-99679998 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA072245",
"HPA075539"
] | [
"CP35",
"P450PCN3",
"PCN3"
] | [
"Cancer-related genes",
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Lipid metabolism",
"Steroid metabolism"
] | [
"Monooxygenase",
"Oxidoreductase"
] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [
"Vesicles"
] | [] | [] | Approved | null | null | 2 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 9: Non-specific - Receptor signaling | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 26: Kidney & Intestine - Metabolism | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,243 | 3 |
ENSG00000106261 | ZKSCAN1 | Zinc finger with KRAB and SCAN domains 1 | [
"P17029"
] | 7 | 100015572-100041689 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006672"
] | [
"KOX18",
"PHZ-37",
"ZNF139",
"ZNF36",
"ZSCAN33"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Mitochondria"
] | [] | [] | Approved | Uncertain | null | 14 | Yes | No | Cluster 30: Non-specific - DNA binding | Cluster 6: Non-specific - Immune response | Cluster 71: Lymphoma - Inflammatory response | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,244 | 8 |
ENSG00000106266 | SNX8 | Sorting nexin 8 | [
"Q9Y5X2"
] | 7 | 2251770-2354318 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA057296",
"HPA060194"
] | [
"Mvp1"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | Approved | null | 6 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 47: Endothelial cells - Vasculature | Cluster 55: Lymphoma - Immune response | Cluster 82: Dendritic cells - Antigen presentation | Cluster 18: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,246 | 7 |
ENSG00000106278 | PTPRZ1 | Protein tyrosine phosphatase receptor type Z1 | [
"P23471"
] | 7 | 121873089-122062036 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015103"
] | [
"phosphacan",
"PTP18",
"PTPRZ",
"PTPZ",
"RPTPB"
] | [
"Enzymes",
"Plasma proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Cytosol"
] | [
"Vesicles"
] | [
"Secreted in brain"
] | [
"Enzyme"
] | Approved | Enhanced | null | 9 | null | null | null | Cluster 21: Non-specific - Metabolism | Cluster 69: Skin cancer - ECM organization | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 73: Brain - Neuronal signaling | Tissue enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 17 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 3,248 | 4 |
ENSG00000106299 | WASL | WASP like actin nucleation promoting factor | [
"O00401"
] | 7 | 123681943-123749003 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005399",
"HPA005750"
] | [
"N-WASP",
"NWASP",
"WASPB"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis",
"Transcription",
"Transcription regulation"
] | [
"Actin-binding"
] | [] | [
"Cytosol"
] | [
"Nucleoli"
] | [] | [] | Approved | Supported | null | 75 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 51: Neurons - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,250 | 8 |
ENSG00000106302 | HYAL4 | Hyaluronidase 4 | [
"Q2M3T9"
] | 7 | 123828983-123877481 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA029453"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosidase",
"Hydrolase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 1 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 9: Non-specific - Receptor signaling | Cluster 66: Non-specific - Mitochondria | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cancer enriched | Detected in some | 7 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,251 | 7 |
ENSG00000106304 | SPAM1 | Sperm adhesion molecule 1 | [
"P38567"
] | 7 | 123925237-123971414 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017984"
] | [
"HYAL5",
"PH-20",
"SPAG15"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [
"Glycosidase",
"Hydrolase"
] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | null | null | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in single | 37 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in some | 39 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,252 | 8 |
ENSG00000106305 | AIMP2 | Aminoacyl tRNA synthetase complex interacting multifunctional protein 2 | [
"Q13155"
] | 7 | 6009255-6023834 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019098",
"HPA020057"
] | [
"JTV-1",
"JTV1",
"p38",
"PRO0992"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Differentiation",
"Protein biosynthesis"
] | [
"Developmental protein"
] | [
"Disease variant",
"Leukodystrophy"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Supported | null | 104 | null | Yes | Cluster 33: Non-specific - ATP binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 67: Non-specific - Unknown function | Cluster 17: Non-specific - RNA processing | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Colon Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe"
] | [
"Breast Invasive Carcinoma",
"Colon Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 3,253 | 7 |
ENSG00000106327 | TFR2 | Transferrin receptor 2 | [
"Q9UP52"
] | 7 | 100620416-100642779 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016255",
"HPA017171",
"HPA073125"
] | [
"HFE3",
"TFRC2"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Receptor"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Enhanced | null | 4 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 15: Non-specific - Transcription | Cluster 47: Leukemia - Hemostasis | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 53: Liver - Plasma proteins | Tissue enriched | Detected in some | 15 | Cancer enriched | Detected in some | 7 | Cancer enriched | Detected in some | 164 | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 23 | 0 | 0 | 0 | [] | [] | [] | 3,254 | 9 |
ENSG00000106328 | FSCN3 | Fascin actin-bundling protein 3 | [
"Q9NQT6"
] | 7 | 127591409-127602144 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA075174"
] | [] | [
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | Cluster 2: Neurons - Nucleosome | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 23: Testis - Spermatogenesis | Tissue enriched | Detected in single | 173 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in many | 10 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,255 | 8 |
ENSG00000106330 | MOSPD3 | Motile sperm domain containing 3 | [
"O75425"
] | 7 | 100612102-100615384 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041137"
] | [
"CDS3",
"NET30"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 13 | null | No | Cluster 9: T-regs - Cell cycle regulation | Cluster 19: Astrocytes - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 47: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 6 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,256 | 3 |
ENSG00000106333 | PCOLCE | Procollagen C-endopeptidase enhancer | [
"Q15113"
] | 7 | 100602363-100608175 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017623",
"HPA042927"
] | [
"PCPE",
"PCPE1"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Golgi apparatus",
"Vesicles"
] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | Approved | Approved | null | 3 | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 44: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 3,258 | 6 |
ENSG00000106336 | FBXO24 | F-box protein 24 | [
"O75426"
] | 7 | 100583982-100601117 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050951"
] | [
"FBX24"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 4 | null | null | null | Cluster 25: Non-specific - Transcription | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in some | 53 | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in some | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 3,259 | 3 |
ENSG00000106341 | PPP1R17 | Protein phosphatase 1 regulatory subunit 17 | [
"O96001"
] | 7 | 31687215-31708455 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047819",
"HPA073123"
] | [
"C7orf16",
"GSBS"
] | [
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Protein phosphatase inhibitor"
] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 38: Sub-cortical - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 4 | Group enriched | Detected in some | 4 | Immune cell enriched | Detected in some | 4 | 0 | 0 | 0 | [] | [] | [] | 3,260 | 2 |
ENSG00000106344 | RBM28 | RNA binding motif protein 28 | [
"Q9NW13"
] | 7 | 128297685-128343908 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019058",
"HPA026672",
"HPA031519"
] | [
"FLJ10377"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"RNA-binding"
] | [
"Disease variant",
"Hypotrichosis",
"Intellectual disability"
] | [
"Nucleoli"
] | [] | [] | [] | Supported | Enhanced | null | 86 | null | No | Cluster 14: Non-specific - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 39: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 3,261 | 1 |
ENSG00000106346 | USP42 | Ubiquitin specific peptidase 42 | [
"Q9H9J4"
] | 7 | 6104949-6161564 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006939",
"HPA064800"
] | [
"FLJ12697"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis",
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli"
] | [] | [] | Approved | null | null | 2 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 16: Non-specific - Transcription | Cluster 67: Non-specific - Unknown function | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in single | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,262 | 5 |
ENSG00000106348 | IMPDH1 | Inosine monophosphate dehydrogenase 1 | [
"P20839"
] | 7 | 128392277-128410252 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001400"
] | [
"LCA11",
"RP10",
"sWSS2608"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"GMP biosynthesis",
"Purine biosynthesis"
] | [
"DNA-binding",
"Oxidoreductase",
"RNA-binding"
] | [
"Disease variant",
"FDA approved drug targets",
"Leber congenital amaurosis",
"Retinitis pigmentosa"
] | [
"Cytosol",
"Rods & Rings"
] | [] | [] | [] | Supported | Approved | null | 4 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 32: Cerebral cortex - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 5 | 2 | 2 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,263 | 3 |
ENSG00000106351 | AGFG2 | ArfGAP with FG repeats 2 | [
"O95081"
] | 7 | 100539203-100568220 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019689",
"HPA020129",
"HPA073562"
] | [
"HRBL",
"RABR"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | null | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 51: Neurons - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 82: Salivary gland - Secretion | Tissue enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,264 | 1 |
ENSG00000106355 | LSM5 | LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated | [
"Q9Y4Y9"
] | 7 | 32485338-32495283 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019054"
] | [
"YER146W"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Ribonucleoprotein",
"RNA-binding"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 30 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 31: Non-specific - Transcription | Cluster 67: Non-specific - Unknown function | Cluster 97: Non-specific - Cellular respiration | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 4 | 0 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,265 | 2 |
ENSG00000106366 | SERPINE1 | Serpin family E member 1 | [
"P05121"
] | 7 | 101127104-101139247 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB068501"
] | [
"PAI",
"PAI1",
"PLANH1"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Protease inhibitor",
"Serine protease inhibitor"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme inhibitor"
] | null | Uncertain | null | 16 | null | No | Cluster 14: Non-specific - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 15: Kidney cancer - Membrane components | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 25 | 6 | 2 | 5 | [] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 3,266 | 6 |
ENSG00000106367 | AP1S1 | Adaptor related protein complex 1 subunit sigma 1 | [
"P61966"
] | 7 | 101154456-101161596 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA060945"
] | [
"AP19",
"CLAPS1",
"EKV3",
"SIGMA1A",
"WUGSC:H_DJ0747G18.2"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [
"Deafness",
"Ichthyosis",
"Intellectual disability",
"Neuropathy"
] | [
"Golgi apparatus",
"Vesicles"
] | [] | [] | [] | Supported | Supported | null | 18 | null | Yes | Cluster 13: Non-specific - Mitochondria | Cluster 33: Neurons - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | 3,267 | 5 |
ENSG00000106384 | MOGAT3 | Monoacylglycerol O-acyltransferase 3 | [
"Q86VF5"
] | 7 | 101195007-101201038 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011940"
] | [
"DC7",
"DGAT2L2",
"MGAT3"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Glycerol metabolism",
"Lipid biosynthesis",
"Lipid metabolism"
] | [
"Acyltransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Group enriched | Detected in some | 13 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 3,268 | 1 |
ENSG00000106392 | C1GALT1 | Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | [
"Q9NS00"
] | 7 | 7156934-7248616 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011294",
"HPA012819"
] | [
"C1GALT",
"T-synthase"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Angiogenesis",
"Differentiation"
] | [
"Developmental protein",
"Glycosyltransferase",
"Transferase"
] | [] | [
"Nuclear bodies",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 2 | null | null | Cluster 32: Basophils - Transcription | Cluster 30: White matter - Myelination | Cluster 67: Non-specific - Unknown function | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,269 | 8 |
ENSG00000106397 | PLOD3 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 | [
"O60568"
] | 7 | 101205977-101218420 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA075391"
] | [
"LH3"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Dioxygenase",
"Glycosyltransferase",
"Multifunctional enzyme",
"Oxidoreductase",
"Transferase"
] | [
"Disease variant"
] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Enzyme"
] | null | Approved | null | 41 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 30: White matter - Myelination | Cluster 69: Skin cancer - ECM organization | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 5 | 0 | 5 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 3,270 | 1 |
ENSG00000106399 | RPA3 | Replication protein A3 | [
"P35244"
] | 7 | 7636518-7718607 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA005708"
] | [
"REPA3"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA recombination",
"DNA repair",
"DNA replication"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 327 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 21: Non-specific - Metabolism | Cluster 30: Non-specific - Gene expression regulation | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 6 | 2 | 5 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,271 | 7 |
ENSG00000106400 | ZNHIT1 | Zinc finger HIT-type containing 1 | [
"O43257"
] | 7 | 101218165-101224190 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019043"
] | [
"CG1I",
"H_DJ0747G18.14",
"ZNFN4A1"
] | [
"Predicted intracellular proteins"
] | [] | [
"Chromatin regulator"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 53 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 27: Non-specific - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 31: Liver - Metabolism & Coagulation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,272 | 1 |
ENSG00000106404 | CLDN15 | Claudin 15 | [
"P56746"
] | 7 | 101232092-101238820 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 77: Intestine - Digestion | Group enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 3,273 | 5 |
ENSG00000106410 | NOBOX | NOBOX oogenesis homeobox | [
"O60393"
] | 7 | 144397240-144410227 | Evidence at protein level | No human protein/transcript evidence | Evidence at protein level | Evidence at protein level | [] | [
"OG2",
"Og2x"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Oogenesis",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Disease variant",
"Premature ovarian failure"
] | [] | [] | [] | [] | null | null | null | null | null | null | null | null | Cluster 51: Myeloma - Immunoglobulins | Cluster 96: Enteroendocrine cells - Neuropeptide signaling | null | Not detected | Not detected | null | Not detected | Not detected | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,274 | 6 |
ENSG00000106415 | GLCCI1 | Glucocorticoid induced 1 | [
"Q86VQ1"
] | 7 | 7968796-8094272 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001674",
"HPA005987"
] | [
"FAM117C",
"GIG18",
"TSSN1"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoli"
] | [] | [] | [] | Approved | Approved | null | 10 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 34: Non-specific - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,275 | 1 |
ENSG00000106443 | PHF14 | PHD finger protein 14 | [
"O94880"
] | 7 | 10973336-11169623 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000538",
"HPA017376"
] | [
"KIAA0783"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Approved | Supported | null | 27 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 37: Neurons - Mixed function | Cluster 67: Non-specific - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 3,277 | 3 |
ENSG00000106459 | NRF1 | Nuclear respiratory factor 1 | [
"Q16656"
] | 7 | 129611720-129757082 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029329"
] | [
"ALPHA-PAL",
"EWG"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 18 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 6: Non-specific - Immune response | Cluster 6: Leukemia - Signal transduction | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,278 | 4 |
ENSG00000106460 | TMEM106B | Transmembrane protein 106B | [
"Q9NUM4"
] | 7 | 12211270-12243367 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA058342"
] | [
"FLJ11273",
"MGC33727"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [
"Amyotrophic lateral sclerosis",
"Disease variant",
"Leukodystrophy",
"Neurodegeneration"
] | [
"Endosomes",
"Lysosomes"
] | [] | [] | [] | Supported | Approved | null | 29 | null | null | Cluster 27: T-cells - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 67: Non-specific - Unknown function | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,279 | 2 |
ENSG00000106462 | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit | [
"Q15910"
] | 7 | 148807257-148884321 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009589",
"HPA029131"
] | [
"ENX-1",
"EZH1",
"KMT6",
"KMT6A"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Methyltransferase",
"Repressor",
"Transferase"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 275 | null | null | Cluster 9: T-regs - Cell cycle regulation | null | Cluster 39: Non-specific - Transcription | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in many | null | 4 | 2 | 3 | [] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,280 | 4 |
ENSG00000106477 | CEP41 | Centrosomal protein 41 | [
"Q9BYV8"
] | 7 | 130393771-130442433 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024090",
"HPA062216"
] | [
"DKFZp762H1311",
"FLJ22445",
"JBTS15",
"TSGA14"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation",
"Protein transport",
"Transport"
] | [] | [
"Autism",
"Autism spectrum disorder",
"Ciliopathy",
"Joubert syndrome"
] | [
"Primary cilium"
] | [
"Basal body"
] | [] | [] | Supported | Uncertain | null | 1 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 17: Choroid plexus - Cilium | Cluster 39: Non-specific - Transcription | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Rectum Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 3,281 | 3 |
ENSG00000106479 | ZNF862 | Zinc finger protein 862 | [
"O60290"
] | 7 | 149838375-149867479 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA024154"
] | [] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [
"Disease variant"
] | [
"Mitochondria"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 33: Non-specific - ATP binding | Cluster 6: Non-specific - Immune response | Cluster 39: Non-specific - Transcription | Cluster 7: Non-specific - Transcription | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,282 | 3 |
ENSG00000106483 | SFRP4 | Secreted frizzled related protein 4 | [
"Q6FHJ7"
] | 7 | 37905932-38025695 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA009712",
"HPA050585"
] | [
"FRP-4",
"frpHE",
"FRZB-2"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Differentiation",
"Wnt signaling pathway"
] | [
"Developmental protein"
] | [
"Cancer-related genes"
] | [] | [] | [
"Secreted in female reproductive system"
] | [
"Developmental protein"
] | null | Enhanced | null | 5 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,283 | 3 |
ENSG00000106484 | MEST | Mesoderm specific transcript | [
"Q5EB52"
] | 7 | 130486171-130506465 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA005623"
] | [
"PEG1"
] | [
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [] | [
"Golgi apparatus",
"Cytosol"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Approved | null | null | 6 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 5: Rhabdoid - Unknown function | Cluster 108: Fibroblasts - ECM organization | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enriched | Detected in all | 7 | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Group enriched | Detected in many | 4 | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 3,284 | 4 |
ENSG00000106524 | ANKMY2 | Ankyrin repeat and MYND domain containing 2 | [
"Q8IV38"
] | 7 | 16599779-16645817 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA067100"
] | [
"DKFZP564O043",
"ZMYND20"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | null | null | 12 | null | null | Cluster 15: NK-cells - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 41: Striated muscle - Muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,286 | 8 |
ENSG00000106526 | ACTR3C | Actin related protein 3C | [
"Q9C0K3"
] | 7 | 150243916-150323725 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [] | [
"ARP11"
] | [
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | Cluster 34: B-cells - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 69: Parathyroid gland - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 3,287 | 9 |
ENSG00000106536 | POU6F2 | POU class 6 homeobox 2 | [
"P78424"
] | 7 | 38977909-39493095 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"RPF-1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | null | null | 103 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in single | null | Cancer enhanced | Detected in single | null | Not detected | Not detected | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,288 | 5 |
ENSG00000106538 | RARRES2 | Retinoic acid receptor responder 2 | [
"Q99969"
] | 7 | 150338317-150341662 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"HP10433",
"TIG2"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Chemotaxis",
"Differentiation",
"Inflammatory response"
] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"Other"
] | null | null | null | 2 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 36: Choroid plexus - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 108: Fibroblasts - ECM organization | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 8 | 4 | 2 | 3 | [
"Bladder Urothelial Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 3,290 | 4 |
ENSG00000106541 | AGR2 | Anterior gradient 2, protein disulphide isomerase family member | [
"O95994"
] | 7 | 16791811-16833433 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007912"
] | [
"AG2",
"HAG-2",
"PDIA17",
"XAG-2"
] | [
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant",
"Proto-oncogene"
] | [
"Endoplasmic reticulum"
] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Supported | Enhanced | null | 296 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,291 | 9 |
ENSG00000106546 | AHR | Aryl hydrocarbon receptor | [
"P35869"
] | 7 | 16916359-17346152 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005072",
"HPA029722",
"HPA029723"
] | [
"bHLHe76"
] | [
"Cancer-related genes",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"Cell cycle",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Receptor",
"Repressor"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets",
"Retinitis pigmentosa"
] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 60 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 30: White matter - Myelination | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,292 | 5 |
ENSG00000106554 | CHCHD3 | Coiled-coil-helix-coiled-coil-helix domain containing 3 | [
"Q9NX63"
] | 7 | 132784870-133082090 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042935"
] | [
"FLJ20420",
"Mic19",
"MICOS19",
"MINOS3",
"PPP1R22"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 84 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 23: Choroid plexus - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 55: Myocytes - Oxidative muscle function | Cluster 62: Skeletal muscle - Muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,293 | 6 |
ENSG00000106560 | GIMAP2 | GTPase, IMAP family member 2 | [
"Q9UG22"
] | 7 | 150685697-150693641 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA013589",
"HPA014746"
] | [
"DKFZp586D0824",
"HIMAP2",
"IAN12",
"IMAP2"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Lipid droplets"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 4 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 43: Hindbrain - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 3,294 | 2 |
ENSG00000106565 | TMEM176B | Transmembrane protein 176B | [
"Q3YBM2"
] | 7 | 150791285-150801360 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047509"
] | [
"LR8",
"MS4B2"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Differentiation"
] | [] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | Approved | Approved | null | 4 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 22: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 16: Liver & Kidney - Metabolism | Tissue enriched | Detected in all | 5 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,295 | 4 |
ENSG00000106571 | GLI3 | GLI family zinc finger 3 | [
"P10071"
] | 7 | 41960949-42264100 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA005534"
] | [
"ACLS",
"GCPS",
"PAP-A",
"PAPA",
"PAPA1",
"PAPB",
"PHS",
"PPDIV"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Vesicles"
] | [] | [] | Approved | Approved | null | 17 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 54: Non-specific - Transcription | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 3,296 | 9 |
ENSG00000106588 | PSMA2 | Proteasome 20S subunit alpha 2 | [
"P25787"
] | 7 | 42916828-42932185 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008188"
] | [
"HC3",
"MU",
"PMSA2"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 185 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 21: Non-specific - Metabolism | Cluster 67: Non-specific - Unknown function | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 45: Liver - Metabolism & Coagulation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 3,297 | 3 |
ENSG00000106591 | MRPL32 | Mitochondrial ribosomal protein L32 | [
"Q9BYC8"
] | 7 | 42932376-42948958 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048965"
] | [
"bMRP-59b",
"HSPC283",
"L32mt",
"MRP-L32"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Other"
] | null | Uncertain | null | 51 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 23: Choroid plexus - Mixed function | Cluster 67: Non-specific - Unknown function | Cluster 103: Non-specific - Basic cellular processes | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,298 | 1 |
ENSG00000106603 | COA1 | Cytochrome c oxidase assembly factor 1 | [
"Q9GZY4"
] | 7 | 43608456-43729717 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011944"
] | [
"C7orf44",
"FLJ10803",
"MITRAC15"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Approved | null | 4 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 31: Non-specific - Transcription | Cluster 67: Non-specific - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,299 | 3 |
ENSG00000106605 | BLVRA | Biliverdin reductase A | [
"P53004"
] | 7 | 43758680-43807342 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019709",
"HPA042865",
"HPA054322"
] | [
"BLVR"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 17 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 67: Non-specific - Unknown function | Cluster 10: Epididymal principal cells - Sperm maturation microenvironment | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 3,300 | 1 |
ENSG00000106608 | URGCP | Upregulator of cell proliferation | [
"Q8TCY9"
] | 7 | 43875894-43926411 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019879",
"HPA020134",
"HPA029468"
] | [
"DKFZp666G166",
"DKFZp686O0457",
"FLJ20654",
"KIAA1507",
"URG4"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell cycle"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 1 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 1: Neurons - Mixed function | Cluster 67: Non-specific - Unknown function | Cluster 22: Non-specific - Basic cellular functions | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,301 | 3 |
ENSG00000106609 | TMEM248 | Transmembrane protein 248 | [
"Q9NWD8"
] | 7 | 66921225-66958551 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA016495"
] | [
"C7orf42",
"FLJ10099",
"FLJ13090"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | 21 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 23: Choroid plexus - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 8: Non-specific - Secretory pathway | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | 3,302 | 1 |
ENSG00000106615 | RHEB | Ras homolog, mTORC1 binding | [
"Q15382"
] | 7 | 151466012-151520120 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB019436"
] | [
"RHEB2"
] | [
"Cancer-related genes",
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Uncertain | null | 34 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 14: Neurons - Synaptic function | Cluster 39: Non-specific - Transcription | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,303 | 8 |
ENSG00000106617 | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2 | [
"Q9UGJ0"
] | 7 | 151556124-151877125 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004246",
"CAB018641"
] | [
"AAKG",
"AAKG2",
"CMH6",
"H91620p",
"WPWS"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Fatty acid biosynthesis",
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid metabolism"
] | [] | [
"Cardiomyopathy",
"Disease variant",
"FDA approved drug targets",
"Glycogen storage disease"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 9 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 38: Sub-cortical - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 35: Non-specific - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 3,304 | 8 |
ENSG00000106624 | AEBP1 | AE binding protein 1 | [
"Q8IUX7"
] | 7 | 44104345-44114562 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009966",
"HPA047724",
"HPA063595",
"HPA064970"
] | [
"ACLP"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Calmodulin-binding",
"DNA-binding",
"Repressor"
] | [
"Disease variant",
"Ehlers-Danlos syndrome"
] | [
"Vesicles"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Secreted - unknown location"
] | [
"Transcription"
] | Supported | Supported | null | null | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 39: Astrocytes - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enriched | Detected in all | 5 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 5 | 2 | 2 | 1 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,305 | 3 |
ENSG00000106628 | POLD2 | DNA polymerase delta 2, accessory subunit | [
"P49005"
] | 7 | 44114631-44124358 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026745"
] | [] | [
"Essential proteins",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA excision",
"DNA repair",
"DNA replication"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 26 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 19: Astrocytes - Mixed function | Cluster 67: Non-specific - Unknown function | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 4 | 2 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,306 | 4 |
ENSG00000106631 | MYL7 | Myosin light chain 7 | [
"Q01449"
] | 7 | 44138864-44141332 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA013331",
"CAB033884",
"HPA039262"
] | [
"MYL2A",
"MYLC2A"
] | [
"Predicted intracellular proteins"
] | [] | [
"Motor protein",
"Muscle protein",
"Myosin"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 5 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 15: Kidney cancer - Membrane components | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 35: Non-specific - Mixed function | Tissue enriched | Detected in many | 853 | Cancer enriched | Detected in some | 6 | Cancer enriched | Detected in some | 7 | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,307 | 3 |
ENSG00000106633 | GCK | Glucokinase | [
"P35557"
] | 7 | 44143213-44198170 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007034",
"HPA007093"
] | [
"HK4",
"MODY2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Glycolysis"
] | [
"Allosteric enzyme",
"Kinase",
"Transferase"
] | [
"Diabetes mellitus",
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 3 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 10: Ciliated cells - Ion channel activity | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 3,308 | 9 |
ENSG00000106635 | BCL7B | BAF chromatin remodeling complex subunit BCL7B | [
"Q9BQE9"
] | 7 | 73536356-73557690 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049943",
"HPA058069"
] | [
"SMARCJ2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Differentiation",
"Wnt signaling pathway"
] | [] | [
"Allergen",
"Williams-Beuren syndrome"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 41 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 38: Sub-cortical - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 3,309 | 4 |
ENSG00000106636 | YKT6 | YKT6 v-SNARE homolog | [
"O15498"
] | 7 | 44200959-44214294 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030817",
"HPA030818"
] | [] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [
"Transferase"
] | [] | [
"Cytosol"
] | [
"Mitochondria"
] | [] | [] | Approved | Approved | null | 37 | No | No | Cluster 45: Eosinophils - Unknown function | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 67: Non-specific - Unknown function | Cluster 8: Non-specific - Secretory pathway | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 3,310 | 5 |
ENSG00000106638 | TBL2 | Transducin beta like 2 | [
"Q9Y4P3"
] | 7 | 73567537-73578791 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007477",
"HPA051533"
] | [
"DKFZP43N024",
"WBSCR13",
"WS-betaTRP"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Williams-Beuren syndrome"
] | [
"Cytosol"
] | [] | [] | [] | Supported | null | null | 36 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 48: Non-specific - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 21: Testis - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,311 | 6 |
ENSG00000106648 | GALNTL5 | Polypeptide N-acetylgalactosaminyltransferase like 5 | [
"Q7Z4T8"
] | 7 | 151956379-152019929 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA011140"
] | [
"GalNAc-T5L",
"GALNT15"
] | [
"Disease related genes",
"Predicted membrane proteins"
] | [
"Differentiation",
"Spermatogenesis"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 1 | null | null | null | null | null | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 67: Testis - Mixed function | Tissue enriched | Detected in some | 6 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,312 | 4 |
ENSG00000106665 | CLIP2 | CAP-Gly domain containing linker protein 2 | [
"Q9UDT6"
] | 7 | 74289407-74405935 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020430",
"CAB020767"
] | [
"CLIP",
"CLIP-115",
"CYLN2",
"KIAA0291",
"WBSCR3",
"WBSCR4",
"WSCR3",
"WSCR4"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Williams-Beuren syndrome"
] | [
"Golgi apparatus",
"Plasma membrane"
] | [] | [] | [] | Approved | Enhanced | null | 7 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 6: Non-specific - Immune response | Cluster 55: Lymphoma - Immune response | Cluster 82: Dendritic cells - Antigen presentation | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,313 | 5 |
ENSG00000106682 | EIF4H | Eukaryotic translation initiation factor 4H | [
"Q15056"
] | 7 | 74174231-74197122 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030542"
] | [
"KIAA0038",
"WBSCR1",
"WSCR1"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Protein biosynthesis"
] | [
"Initiation factor",
"RNA-binding"
] | [
"Cancer-related genes",
"Williams-Beuren syndrome"
] | [
"Cytosol"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [] | [] | Approved | Approved | null | 13 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 27: Non-specific - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in all | 7 | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,314 | 4 |
ENSG00000106683 | LIMK1 | LIM domain kinase 1 | [
"P53667"
] | 7 | 74082933-74122525 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028516",
"HPA073571"
] | [
"LIMK"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Cancer-related genes",
"Williams-Beuren syndrome"
] | [
"Nuclear speckles",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 22 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 39: Non-specific - Transcription | Cluster 109: Neurons - Neuronal signaling | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,315 | 9 |
ENSG00000106688 | SLC1A1 | Solute carrier family 1 member 1 | [
"P43005"
] | 9 | 4490468-4587469 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA062356"
] | [
"EAAC1",
"EAAT3",
"hEAAC1"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Amino-acid transport",
"Symport",
"Transport"
] | [] | [
"Disease variant",
"Schizophrenia"
] | [] | [] | [] | [] | null | Enhanced | null | 114 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 29: Forebrain - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 26: Kidney & Intestine - Metabolism | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,317 | 6 |
ENSG00000106689 | LHX2 | LIM homeobox 2 | [
"P50458"
] | 9 | 124001670-124033301 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000838"
] | [
"hLhx2",
"LH-2"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | Supported | 31 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 54: Non-specific - Transcription | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 73: Brain - Neuronal signaling | Group enriched | Detected in some | 6 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,318 | 2 |
ENSG00000106692 | FKTN | Fukutin | [
"O75072"
] | 9 | 105558122-105653820 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA012820"
] | [
"FCMD",
"LGMD2M"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Transferase"
] | [
"Cardiomyopathy",
"Congenital muscular dystrophy",
"Disease variant",
"Dystroglycanopathy",
"Limb-girdle muscular dystrophy",
"Lissencephaly"
] | [] | [] | [] | [] | null | Approved | null | 2 | null | null | null | Cluster 28: Oligodendrocytes - Mixed function | Cluster 43: Non-specific - Basic cellular processes | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,319 | 2 |
ENSG00000106701 | FSD1L | Fibronectin type III and SPRY domain containing 1 like | [
"Q9BXM9"
] | 9 | 105447796-105552433 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035138"
] | [
"CCDC10",
"CSDUFD1",
"FSD1CL",
"FSD1NL"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [
"Golgi apparatus",
"Vesicles"
] | [] | [] | Approved | Approved | null | null | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 39: Astrocytes - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 3,320 | 3 |
ENSG00000106714 | CNTNAP3 | Contactin associated protein family member 3 | [
"Q9BZ76"
] | 9 | 39064710-39288315 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA047731"
] | [
"CASPR3",
"CNTNAP3A",
"FLJ14195",
"KIAA1714"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Cell adhesion"
] | null | Uncertain | null | null | null | null | Cluster 4: Neutrophils - Degranulation | Cluster 33: Neurons - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 2: Non-specific - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in many | 4 | Immune cell enriched | Detected in single | 18 | 1 | 0 | 1 | [] | [
"Bladder Urothelial Carcinoma"
] | [
"Bladder Urothelial Carcinoma"
] | 3,321 | 1 |
ENSG00000106723 | SPIN1 | Spindlin 1 | [
"Q9Y657"
] | 9 | 88388430-88478694 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000162",
"HPA068784"
] | [
"SPIN",
"TDRD24"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Meiosis",
"Wnt signaling pathway"
] | [
"Chromatin regulator",
"Developmental protein"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 24 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 43: Non-specific - Basic cellular processes | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,322 | 7 |
ENSG00000106733 | NMRK1 | Nicotinamide riboside kinase 1 | [
"Q9NWW6"
] | 9 | 75060573-75088217 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049795"
] | [
"bA235O14.2",
"C9orf95",
"FLJ20559",
"NRK1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Pyridine nucleotide biosynthesis"
] | [
"Kinase",
"Transferase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Centrosome"
] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 11: T-cells - Unknown function | Cluster 31: Non-specific - Transcription | Cluster 51: Myeloma - Immunoglobulins | Cluster 84: Apical squamous epithelium - Cornification | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 7 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,323 | 7 |
ENSG00000106771 | TMEM245 | Transmembrane protein 245 | [
"Q9H330"
] | 9 | 109015135-109119947 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA023892"
] | [
"C9orf5",
"CG-2"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | null | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 21: Non-specific - Metabolism | Cluster 43: Non-specific - Basic cellular processes | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 3,324 | 1 |
ENSG00000106772 | PRUNE2 | Prune homolog 2 with BCH domain | [
"Q8WUY3"
] | 9 | 76611376-76906114 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017269",
"HPA022470",
"HPA031079"
] | [
"A214N16.3",
"bA214N16.3",
"BMCC1",
"BNIPXL",
"C9orf65",
"KIAA0367"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 13 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 26: Oligodendrocytes - Mixed function | Cluster 60: Prostate cancer - Unknown function | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Thyroid Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Thyroid Carcinoma"
] | 3,325 | 3 |
ENSG00000106780 | MEGF9 | Multiple EGF like domains 9 | [
"Q9H1U4"
] | 9 | 120600811-120714470 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA014319",
"HPA050238"
] | [
"EGFL5"
] | [
"Plasma proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,326 | 3 |
ENSG00000106785 | TRIM14 | Tripartite motif containing 14 | [
"Q14142"
] | 9 | 98069275-98119222 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053217"
] | [
"KIAA0129"
] | [
"Predicted intracellular proteins"
] | [
"Immunity",
"Innate immunity"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 38 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 43: Hindbrain - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 34: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,327 | 8 |
ENSG00000106789 | CORO2A | Coronin 2A | [
"Q92828"
] | 9 | 98120975-98192637 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041161",
"HPA041302"
] | [
"IR10",
"WDR2"
] | [
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Vesicles",
"Basal body"
] | [] | [] | Approved | Enhanced | null | 11 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 1: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 7: Small intestine - Absorption and Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 3,328 | 8 |
ENSG00000106799 | TGFBR1 | Transforming growth factor beta receptor 1 | [
"P36897"
] | 9 | 99104038-99154192 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002441",
"CAB031481",
"HPA056473"
] | [
"ACVRLK4",
"ALK-5",
"ALK5",
"ESS1",
"MSSE",
"TBR-i",
"TBRI"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis",
"Differentiation",
"Growth regulation"
] | [
"Kinase",
"Receptor",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Aortic aneurysm",
"Craniosynostosis",
"Disease variant"
] | [
"Plasma membrane",
"Primary cilium"
] | [
"Primary cilium tip"
] | [
"Intracellular and membrane"
] | [
"Receptor"
] | Approved | Uncertain | null | 49 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 20: Macrophages & Microglia - Immune response | Cluster 33: Sarcoma - Muscle contraction | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,329 | 6 |
ENSG00000106803 | SEC61B | SEC61 translocon subunit beta | [
"P60468"
] | 9 | 99222064-99230615 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049407"
] | [] | [
"Disease related genes",
"Essential proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Protein transport",
"Translocation",
"Transport"
] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Approved | null | 386 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 21: Non-specific - Metabolism | Cluster 55: Lymphoma - Immune response | Cluster 8: Non-specific - Secretory pathway | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme"
] | 3,330 | 2 |
ENSG00000106804 | C5 | Complement C5 | [
"P01031"
] | 9 | 120932987-121075195 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029339"
] | [
"C5a",
"C5b",
"CPAMD4"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Complement alternate pathway",
"Complement pathway",
"Cytolysis",
"Immunity",
"Inflammatory response",
"Innate immunity"
] | [] | [
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [
"Secreted to blood"
] | [
"Complement pathway"
] | null | Supported | null | 22 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 30 | Cancer enriched | Detected in many | 5 | Cancer enriched | Detected in many | 9 | Cell type enriched | Detected in many | 13 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Colon Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma"
] | 3,331 | 4 |
ENSG00000106809 | OGN | Osteoglycin | [
"P20774"
] | 9 | 92383268-92404696 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA013132"
] | [
"mimecan",
"OIF",
"SLRR3A"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Growth factor"
] | [] | [
"Endoplasmic reticulum"
] | [] | [
"Secreted in other tissues"
] | [
"Growth factor"
] | Supported | Approved | null | 3 | null | null | Cluster 16: Non-specific - Cell proliferation | Cluster 8: Immune cells - Immune response | Cluster 5: Rhabdoid - Unknown function | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in some | 6 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 9 | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 3,332 | 9 |
ENSG00000106819 | ASPN | Asporin | [
"Q9BXN1"
] | 9 | 92456205-92482506 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007894",
"HPA008435",
"HPA024230"
] | [
"FLJ20129",
"PLAP-1",
"SLRR1C"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Biomineralization"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [
"Secreted to extracellular matrix"
] | [
"Other"
] | Uncertain | Approved | null | null | null | null | null | Cluster 25: Non-specific - Transcription | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in single | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 5 | 5 | 0 | 5 | [
"Bladder Urothelial Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Stomach Adenocarcinoma"
] | 3,333 | 8 |
ENSG00000106823 | ECM2 | Extracellular matrix protein 2 | [
"O94769"
] | 9 | 92493554-92536655 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA035347"
] | [] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Nucleoli fibrillar center",
"Endoplasmic reticulum"
] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | Approved | Approved | null | null | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 89: Adipocytes - Lipid metabolism | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 4 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,334 | 9 |
ENSG00000106829 | TLE4 | TLE family member 4, transcriptional corepressor | [
"Q04727"
] | 9 | 79571773-79726882 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065357"
] | [
"E(spl)",
"ESG",
"GRG4"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Wnt signaling pathway"
] | [
"Repressor"
] | [] | [
"Nucleoplasm"
] | [
"Mitochondria"
] | [] | [] | Supported | null | null | 14 | null | null | Cluster 41: Basophils - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,335 | 2 |
ENSG00000106852 | LHX6 | LIM homeobox 6 | [
"Q9UPM6"
] | 9 | 122202577-122229626 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002269",
"HPA047854"
] | [
"hLHX6",
"LHX6.1"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 23 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 74: Non-specific - Signal transduction | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 6 | Low cancer specificity | Detected in many | null | Group enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,336 | 6 |
ENSG00000106853 | PTGR1 | Prostaglandin reductase 1 | [
"Q14914"
] | 9 | 111549722-111599893 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036724"
] | [
"LTB4DH",
"ZADH3"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism",
"Prostaglandin metabolism"
] | [
"Oxidoreductase"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 2 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 29: Forebrain - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 6 | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 3,337 | 6 |
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