ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000106868 | SUSD1 | Sushi domain containing 1 | [
"Q6UWL2"
] | 9 | 112040783-112175297 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048554"
] | [
"DKFZP761E1824"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Approved | Approved | null | null | null | null | Cluster 29: Non-specific - Unknown function | Cluster 1: Neurons - Mixed function | Cluster 43: Non-specific - Basic cellular processes | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,338 | 4 |
ENSG00000106927 | AMBP | Alpha-1-microglobulin/bikunin precursor | [
"P02760"
] | 9 | 114060127-114078328 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001497",
"CAB069436",
"HPA075585"
] | [
"EDC1",
"HCP",
"HI30",
"IATIL",
"ITI",
"ITIL",
"ITILC",
"UTI"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Host-virus interaction"
] | [
"Oxidoreductase",
"Protease inhibitor",
"Serine protease inhibitor"
] | [] | [
"Vesicles"
] | [
"Golgi apparatus",
"Cytosol"
] | [
"Secreted to blood"
] | [
"Enzyme"
] | Approved | Approved | null | 4 | null | null | null | null | Cluster 18: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 68 | Cancer enriched | Detected in some | 8 | Cancer enriched | Detected in many | 107 | Cell type enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,339 | 5 |
ENSG00000106948 | AKNA | AT-hook transcription factor | [
"Q7Z591"
] | 9 | 114334156-114394405 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052367",
"HPA063993"
] | [
"KIAA1968"
] | [
"Predicted intracellular proteins"
] | [
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli fibrillar center",
"Centrosome",
"Cytosol"
] | [] | [] | Supported | null | null | 2 | null | null | Cluster 24: Non-specific - Transcription | Cluster 46: Brainstem - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in all | null | Group enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 3,340 | 6 |
ENSG00000106952 | TNFSF8 | TNF superfamily member 8 | [
"P32971"
] | 9 | 114893343-114930595 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CD153",
"CD30LG"
] | [
"Cancer-related genes",
"CD markers",
"Predicted membrane proteins"
] | [] | [
"Cytokine"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | null | null | 82 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 20: Macrophages & Microglia - Immune response | Cluster 27: Breast cancer - Unknown function | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 4 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 3,341 | 5 |
ENSG00000106976 | DNM1 | Dynamin 1 | [
"Q05193"
] | 9 | 128191655-128255248 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005920",
"HPA049910"
] | [
"DNM"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Endocytosis"
] | [
"Hydrolase",
"Motor protein"
] | [
"Disease variant",
"Epilepsy"
] | [] | [] | [] | [] | null | Enhanced | null | 42 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 15: Kidney cancer - Membrane components | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in all | 5 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,342 | 2 |
ENSG00000106991 | ENG | Endoglin | [
"P17813"
] | 9 | 127815013-127854658 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000096",
"HPA011862",
"HPA067440",
"CAB072873"
] | [
"CD105",
"END",
"HHT1",
"ORW",
"ORW1"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"CD markers",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Angiogenesis",
"Cell adhesion"
] | [] | [
"Cancer-related genes",
"Disease variant"
] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 11 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 47: Endothelial cells - Vasculature | Cluster 64: Connective tissue cells - ECM organization | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 3 | 4 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Stomach Adenocarcinoma"
] | 3,343 | 5 |
ENSG00000106993 | CDC37L1 | Cell division cycle 37 like 1, HSP90 cochaperone | [
"Q7L3B6"
] | 9 | 4679559-4708399 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021175"
] | [
"CDC37B",
"FLJ20639",
"HARC"
] | [
"Predicted intracellular proteins"
] | [] | [
"Chaperone"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 27 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 14: Neurons - Synaptic function | Cluster 21: Lymphoma - Adaptive immune response | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,345 | 4 |
ENSG00000107014 | RLN2 | Relaxin 2 | [
"P04090"
] | 9 | 5299864-5304716 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"bA12D24.1.1",
"bA12D24.1.2",
"H2",
"RLXH2"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Hormone"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Hormone"
] | null | null | null | 2 | null | null | Cluster 24: Non-specific - Transcription | null | Cluster 27: Breast cancer - Unknown function | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 26 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,346 | 2 |
ENSG00000107018 | RLN1 | Relaxin 1 | [
"P04808"
] | 9 | 5334930-5339876 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"H1"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Hormone"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Hormone"
] | null | null | null | 17 | null | null | null | null | Cluster 60: Prostate cancer - Unknown function | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 38: Non-specific - Basic cellular processes | Tissue enriched | Detected in single | 72 | Cancer enriched | Detected in single | 59 | Cancer enriched | Detected in single | 275 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,347 | 5 |
ENSG00000107020 | PLGRKT | Plasminogen receptor with a C-terminal lysine | [
"Q9HBL7"
] | 9 | 5357971-5437925 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008214",
"HPA011144"
] | [
"AD025",
"C9orf46",
"FLJ14688",
"MDS030",
"Plg-RKT"
] | [
"Predicted membrane proteins"
] | [
"Chemotaxis",
"Inflammatory response",
"Plasminogen activation"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Uncertain | Supported | null | 3 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 21: Non-specific - Metabolism | Cluster 21: Lymphoma - Adaptive immune response | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 3 | 0 | 3 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,348 | 4 |
ENSG00000107021 | TBC1D13 | TBC1 domain family member 13 | [
"Q9NVG8"
] | 9 | 128787253-128810430 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045865",
"HPA075988"
] | [
"FLJ10743"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 5 | null | No | Cluster 12: Non-specific - Mitochondrial translation | Cluster 51: Neurons - Mixed function | Cluster 43: Non-specific - Basic cellular processes | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 36: Brain & Liver - Signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 4 | 4 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,349 | 7 |
ENSG00000107036 | RIC1 | RIC1 homolog, RAB6A GEF complex partner 1 | [
"Q4ADV7"
] | 9 | 5629025-5776557 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051578"
] | [
"bA207C16.1",
"KIAA1432"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [
"Disease variant",
"Intellectual disability"
] | [] | [] | [] | [] | null | Supported | null | 5 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 50: Non-specific - Nucleic acid binding | Cluster 47: Leukemia - Hemostasis | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 3,350 | 5 |
ENSG00000107077 | KDM4C | Lysine demethylase 4C | [
"Q9H3R0"
] | 9 | 6720863-7175648 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA069357"
] | [
"GASC1",
"JMJD2C",
"KIAA0780",
"TDRD14C"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Dioxygenase",
"Oxidoreductase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | null | 4 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 25: Non-specific - Transcription | Cluster 47: Leukemia - Hemostasis | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,351 | 1 |
ENSG00000107099 | DOCK8 | Dedicator of cytokinesis 8 | [
"Q8NF50"
] | 9 | 214854-465259 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003218",
"HPA003219",
"HPA073349"
] | [
"FLJ00026",
"FLJ00152",
"FLJ00346",
"ZIR8"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 19 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 46: Lymphoma - Humoral immune response | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,352 | 1 |
ENSG00000107104 | KANK1 | KN motif and ankyrin repeat domains 1 | [
"Q14678"
] | 9 | 470291-746105 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005539",
"HPA056090"
] | [
"ANKRD15",
"KANK",
"KIAA0172"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [
"Tumor suppressor"
] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Approved | null | 17 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 8: Immune cells - Immune response | Cluster 46: Lymphoma - Humoral immune response | Cluster 57: Podocytes - Glomerular filtration | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 3,353 | 5 |
ENSG00000107105 | ELAVL2 | ELAV like RNA binding protein 2 | [
"Q12926"
] | 9 | 23690104-23826337 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022222",
"HPA063001"
] | [
"HEL-N1",
"HuB"
] | [
"Predicted intracellular proteins"
] | [] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | Supported | 12 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 1: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | Cluster 10: Brain - Synaptic signal transduction | Group enriched | Detected in some | 7 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 3,354 | 2 |
ENSG00000107140 | TESK1 | Testis associated actin remodelling kinase 1 | [
"Q15569"
] | 9 | 35605262-35610041 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [] | [] | [] | [] | [] | null | null | null | 7 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 38: Sub-cortical - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,356 | 7 |
ENSG00000107147 | KCNT1 | Potassium sodium-activated channel subfamily T member 1 | [
"Q5JUK3"
] | 9 | 135702185-135795508 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA059880",
"HPA060577"
] | [
"KCa4.1",
"KIAA1422",
"SLACK",
"Slo2.2"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Ion channel",
"Potassium channel"
] | [
"Disease variant",
"Epilepsy"
] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Uncertain | null | null | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in single | 6 | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 3,357 | 3 |
ENSG00000107159 | CA9 | Carbonic anhydrase 9 | [
"Q16790"
] | 9 | 35673928-35681159 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005100",
"CAB017107",
"HPA055207"
] | [
"CAIX",
"MN"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Lyase"
] | [
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 14 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 15: Kidney cancer - Membrane components | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 60: Stomach - Digestion | Tissue enriched | Detected in some | 13 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,358 | 1 |
ENSG00000107164 | FUBP3 | Far upstream element binding protein 3 | [
"Q96I24"
] | 9 | 130578965-130638352 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047658",
"HPA058392"
] | [
"FBP3"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 31 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 19: Astrocytes - Mixed function | Cluster 43: Non-specific - Basic cellular processes | Cluster 17: Non-specific - RNA processing | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 3,359 | 8 |
ENSG00000107165 | TYRP1 | Tyrosinase related protein 1 | [
"P17643"
] | 9 | 12685439-12710285 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000937",
"CAB002520"
] | [
"b-PROTEIN",
"CAS2",
"CATB",
"GP75",
"OCA3",
"TRP",
"TYRP"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Melanin biosynthesis"
] | [
"Monooxygenase",
"Oxidoreductase"
] | [
"Albinism",
"Disease variant"
] | [
"Vesicles"
] | [] | [] | [] | Approved | Enhanced | null | 4 | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 58: Skin - Keratinization | Group enriched | Detected in many | 6 | Cancer enriched | Detected in many | 6 | Cancer enriched | Detected in many | 224 | Group enriched | Detected in some | 65 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,360 | 2 |
ENSG00000107175 | CREB3 | CAMP responsive element binding protein 3 | [
"O43889"
] | 9 | 35732598-35736999 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030978",
"HPA077421"
] | [
"Luman",
"LZIP",
"sLZIP"
] | [
"Predicted membrane proteins",
"Transcription factors"
] | [
"Chemotaxis",
"Host-virus interaction",
"Transcription",
"Transcription regulation",
"Unfolded protein response"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [] | [
"Cytosol"
] | [
"Vesicles",
"Plasma membrane",
"Primary cilium",
"Primary cilium tip",
"Primary cilium transition zone",
"Centrosome",
"Basal body"
] | [] | [] | Supported | null | null | 48 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 19: Astrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,361 | 8 |
ENSG00000107185 | RGP1 | RGP1 homolog, RAB6A GEF complex partner 1 | [
"Q92546"
] | 9 | 35749287-35758585 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020414",
"HPA021085"
] | [
"KIAA0258"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Supported | Approved | null | 7 | null | null | Cluster 32: Basophils - Transcription | Cluster 38: Sub-cortical - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,362 | 2 |
ENSG00000107186 | MPDZ | Multiple PDZ domain crumbs cell polarity complex component | [
"O75970"
] | 9 | 13105706-13279692 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB013512",
"HPA020255",
"HPA026686"
] | [
"MUPP1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction"
] | [] | [] | [
"Centriolar satellite"
] | [
"Basal body"
] | [] | [] | Approved | Uncertain | null | 23 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,363 | 9 |
ENSG00000107187 | LHX3 | LIM homeobox 3 | [
"Q9UBR4"
] | 9 | 136196250-136205128 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Disease variant",
"Dwarfism"
] | [] | [] | [] | [] | null | null | null | 14 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 20: Pituitary gland - Hormone signaling | Tissue enriched | Detected in some | 48 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Cell type enriched | Detected in some | 9 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,364 | 1 |
ENSG00000107223 | EDF1 | Endothelial differentiation related factor 1 | [
"O60869"
] | 9 | 136862119-136866308 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035642"
] | [
"CFAP280",
"EDF-1"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Calmodulin-binding",
"Developmental protein",
"DNA-binding"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | Supported | Approved | null | 22 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 28: Oligodendrocytes - Mixed function | Cluster 43: Non-specific - Basic cellular processes | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 3,366 | 4 |
ENSG00000107242 | PIP5K1B | Phosphatidylinositol-4-phosphate 5-kinase type 1 beta | [
"O14986"
] | 9 | 68705240-69009176 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA009687"
] | [
"MSS4",
"STM7"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Approved | Uncertain | null | 1 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 23: Choroid plexus - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 6 | 4 | 2 | 3 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,367 | 1 |
ENSG00000107249 | GLIS3 | GLIS family zinc finger 3 | [
"Q8NEA6"
] | 9 | 3824127-4348392 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA056426"
] | [
"MGC33662",
"ZNF515"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [
"Congenital hypothyroidism",
"Diabetes mellitus"
] | [
"Nucleoplasm"
] | [
"Golgi apparatus",
"Primary cilium"
] | [] | [] | Approved | Approved | null | 5 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 55: Breast - Lactation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,368 | 2 |
ENSG00000107262 | BAG1 | BAG cochaperone 1 | [
"Q99933"
] | 9 | 33247820-33264720 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002486",
"HPA018121",
"HPA073236"
] | [] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [
"Chaperone"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Supported | null | 51 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 47: Endothelial cells - Vasculature | Cluster 7: Liver cancer - Metabolism | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Rectum Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 3,369 | 3 |
ENSG00000107263 | RAPGEF1 | Rap guanine nucleotide exchange factor 1 | [
"Q13905"
] | 9 | 131576770-131740076 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006426",
"HPA075984"
] | [
"C3G",
"GRF2"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Neurogenesis"
] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | Enhanced | null | 18 | null | null | Cluster 32: Basophils - Transcription | Cluster 44: Non-specific - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,370 | 1 |
ENSG00000107281 | NPDC1 | Neural proliferation, differentiation and control 1 | [
"Q9NQX5"
] | 9 | 137039463-137046179 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008189"
] | [
"CAB-",
"CAB1",
"DKFZp586J0523"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 34 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 32: Cerebral cortex - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 4 | 0 | 4 | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,371 | 8 |
ENSG00000107282 | APBA1 | Amyloid beta precursor protein binding family A member 1 | [
"Q02410"
] | 9 | 69427532-69672371 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA061287"
] | [
"D9S411E",
"MINT1",
"X11"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | null | null | 22 | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 50: Lymphoma - Unknown function | Cluster 109: Neurons - Neuronal signaling | Cluster 10: Brain - Synaptic signal transduction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 3,372 | 7 |
ENSG00000107290 | SETX | Senataxin | [
"Q7Z333"
] | 9 | 132261356-132354986 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024105",
"HPA057269"
] | [
"ALS4",
"AOA2",
"KIAA0625",
"SCAR1",
"Sen1",
"STEX"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"Differentiation",
"DNA damage",
"DNA recombination",
"DNA repair",
"Neurogenesis",
"Spermatogenesis"
] | [
"Helicase",
"Hydrolase"
] | [
"Amyotrophic lateral sclerosis",
"Disease variant",
"Neurodegeneration"
] | [
"Nucleoplasm"
] | [
"Cytokinetic bridge"
] | [] | [] | Supported | Approved | null | 10 | Yes | No | Cluster 35: Neutrophils - Protein binding | Cluster 55: Non-specific - Transcription | Cluster 43: Non-specific - Basic cellular processes | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,373 | 2 |
ENSG00000107295 | SH3GL2 | SH3 domain containing GRB2 like 2, endophilin A1 | [
"Q99962"
] | 9 | 17579066-17797124 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010056",
"HPA026685",
"HPA063573"
] | [
"CNSA2",
"EEN-B1",
"SH3D2A",
"SH3P4"
] | [
"Predicted intracellular proteins"
] | [
"Endocytosis"
] | [] | [] | [
"Microtubules"
] | [
"Cytokinetic bridge",
"Mitotic spindle"
] | [] | [] | Approved | Enhanced | Supported | 48 | Yes | No | null | Cluster 2: Neurons - Nucleosome | Cluster 10: Ciliated cells - Ion channel activity | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Group enriched | Detected in many | 6 | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 4 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,374 | 3 |
ENSG00000107317 | PTGDS | Prostaglandin D2 synthase | [
"P41222"
] | 9 | 136975092-136981742 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA004938",
"CAB009916",
"HPA067456"
] | [
"L-PGDS",
"PGDS"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Fatty acid biosynthesis",
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid metabolism",
"Mast cell degranulation",
"Prostaglandin biosynthesis",
"Prostaglandin metabolism",
"Transport"
] | [
"Isomerase"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Transport"
] | null | Uncertain | null | 19 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 27 | 3 | 0 | 3 | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,375 | 6 |
ENSG00000107331 | ABCA2 | ATP binding cassette subfamily A member 2 | [
"Q9BZC7"
] | 9 | 137007234-137028915 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042886"
] | [
"ABC2"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [
"Translocase"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Vesicles"
] | [] | [] | [] | Supported | Approved | null | 1 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 43: Non-specific - Basic cellular processes | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in all | 9 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 6 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 3,376 | 4 |
ENSG00000107338 | SHB | SH2 domain containing adaptor protein B | [
"Q15464"
] | 9 | 37915898-38069227 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010161",
"HPA049911",
"HPA052108"
] | [] | [
"Predicted intracellular proteins"
] | [
"Angiogenesis",
"Apoptosis",
"Differentiation"
] | [
"Developmental protein"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm",
"Cytoplasmic bodies"
] | [] | [] | Supported | Uncertain | null | 13 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 11: White matter - Signal transduction | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 104: Brain endothelial cells - Blood brain barrier | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 22 | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,377 | 6 |
ENSG00000107341 | UBE2R2 | Ubiquitin conjugating enzyme E2 R2 | [
"Q712K3"
] | 9 | 33817160-33920399 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA061000",
"HPA074334"
] | [
"CDC34B",
"FLJ20419",
"MGC10481",
"UBC3B"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [
"Cytosol"
] | [] | [] | Approved | null | null | 13 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 43: Non-specific - Basic cellular processes | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 3,378 | 2 |
ENSG00000107371 | EXOSC3 | Exosome component 3 | [
"Q9NQT5"
] | 9 | 37759234-37832117 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020485"
] | [
"CGI-102",
"hRrp-40",
"hRrp40p",
"p10",
"RRP40",
"Rrp40p"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"rRNA processing"
] | [
"RNA-binding"
] | [
"Disease variant",
"Neurodegeneration"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 65 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 31: Non-specific - Transcription | Cluster 43: Non-specific - Basic cellular processes | Cluster 22: Non-specific - Basic cellular functions | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,380 | 7 |
ENSG00000107372 | ZFAND5 | Zinc finger AN1-type containing 5 | [
"O76080"
] | 9 | 72351413-72365235 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA018129",
"HPA077824"
] | [
"ZA20D2",
"ZFAND5A",
"ZNF216"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Cytosol"
] | [] | [] | Approved | Approved | null | 8 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 31: Non-specific - Transcription | Cluster 64: Connective tissue cells - ECM organization | Cluster 103: Non-specific - Basic cellular processes | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,381 | 9 |
ENSG00000107404 | DVL1 | Dishevelled segment polarity protein 1 | [
"O14640"
] | 1 | 1335276-1349418 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011538",
"HPA073607"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Wnt signaling pathway"
] | [
"Developmental protein"
] | [
"Dwarfism"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [
"Vesicles",
"Focal adhesion sites"
] | [] | [] | Approved | Approved | null | 30 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 17: Non-specific - RNA processing | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 3,382 | 6 |
ENSG00000107443 | CCNJ | Cyclin J | [
"Q5T5M9"
] | 10 | 96043394-96060870 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA036531"
] | [
"bA690P14.1",
"FLJ10895"
] | [
"Predicted intracellular proteins"
] | [] | [
"Cyclin"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 25: Non-specific - Transcription | Cluster 6: Leukemia - Signal transduction | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 3,384 | 6 |
ENSG00000107447 | DNTT | DNA nucleotidylexotransferase | [
"P04053"
] | 10 | 96304409-96338564 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036532",
"HPA044194"
] | [
"TDT"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Terminal addition"
] | [
"Nucleotidyltransferase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 7 | null | null | Cluster 43: Non-specific - Transcription & Translation | null | Cluster 6: Leukemia - Signal transduction | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 80: Thymus - Adaptive immune response | Tissue enriched | Detected in some | 12 | Cancer enriched | Detected in some | 6 | Cancer enriched | Detected in single | 6 | Cell type enriched | Detected in some | 8 | Immune cell enhanced | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 3,385 | 3 |
ENSG00000107485 | GATA3 | GATA binding protein 3 | [
"P23771"
] | 10 | 8045378-8075198 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016217",
"HPA029730"
] | [
"HDR"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Immunity",
"Innate immunity",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Cancer-related genes",
"Deafness",
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 34 | null | null | Cluster 1: T-cells - Unknown function | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 27: Breast cancer - Unknown function | Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func. | Cluster 9: Skin - Hair follicle development | Tissue enhanced | Detected in many | null | Group enriched | Detected in all | 4 | Group enriched | Detected in many | 10 | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 33 | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 3,386 | 6 |
ENSG00000107518 | ATRNL1 | Attractin like 1 | [
"Q5VV63"
] | 10 | 115093365-115948999 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA038070"
] | [
"ALP",
"FLJ45344",
"KIAA0534"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Mitochondria"
] | [] | [] | [] | Approved | null | null | null | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 35: RS4;11 - Unknown function | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 3,387 | 8 |
ENSG00000107521 | HPS1 | HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 | [
"Q92902"
] | 10 | 98410939-98446963 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA061260"
] | [
"BLOC3S1",
"HPS"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Sensory transduction",
"Vision"
] | [
"Guanine-nucleotide releasing factor"
] | [
"Albinism",
"Disease variant",
"Hermansky-Pudlak syndrome"
] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 49: Hindbrain - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 102: Non-specific - Mixed function | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 3,388 | 1 |
ENSG00000107537 | PHYH | Phytanoyl-CoA 2-hydroxylase | [
"O14832"
] | 10 | 13277796-13302412 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007598",
"HPA011796"
] | [
"PAHX",
"PHYH1",
"RD"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Dioxygenase",
"Oxidoreductase"
] | [
"Cataract",
"Deafness",
"Disease variant",
"Ichthyosis",
"Peroxisome biogenesis disorder",
"Retinitis pigmentosa"
] | [] | [] | [] | [] | null | Enhanced | null | 19 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 23: Choroid plexus - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 3,389 | 8 |
ENSG00000107551 | RASSF4 | Ras association domain family member 4 | [
"Q9H2L5"
] | 10 | 44959407-44995891 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038834",
"HPA077069"
] | [
"AD037",
"MGC44914"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [] | [
"Tumor suppressor"
] | [
"Nucleoplasm",
"Nucleoli"
] | [
"Cell Junctions",
"Cytokinetic bridge",
"Mitotic spindle",
"Cytosol"
] | [] | [] | Approved | Approved | null | 11 | Yes | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 19: Astrocytes - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 8 | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 3,390 | 3 |
ENSG00000107554 | DNMBP | Dynamin binding protein | [
"Q6XZF7"
] | 10 | 99875577-100009947 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA037878",
"HPA058216"
] | [
"ARHGEF36",
"KIAA1010",
"Tuba"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [
"Cataract",
"Disease variant"
] | [
"Nucleoli",
"Golgi apparatus",
"Cytosol"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [] | [] | Approved | Uncertain | null | 24 | Yes | No | Cluster 14: Non-specific - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 3,391 | 6 |
ENSG00000107562 | CXCL12 | C-X-C motif chemokine ligand 12 | [
"P48061"
] | 10 | 44370165-44386493 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB017564"
] | [
"PBSF",
"SCYB12",
"SDF-1a",
"SDF-1b",
"SDF1",
"SDF1A",
"SDF1B",
"TLSF-a",
"TLSF-b",
"TPAR1"
] | [
"Predicted secreted proteins"
] | [
"Chemotaxis",
"Host-virus interaction"
] | [
"Cytokine",
"Growth factor"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Chemokine"
] | null | Approved | null | 22 | null | null | null | Cluster 8: Immune cells - Immune response | Cluster 44: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,393 | 5 |
ENSG00000107566 | ERLIN1 | ER lipid raft associated 1 | [
"O75477"
] | 10 | 100150094-100186033 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011252"
] | [
"C10orf69",
"Erlin-1",
"KE04",
"SPFH1",
"SPG62"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Cholesterol metabolism",
"Lipid metabolism",
"Steroid metabolism",
"Sterol metabolism"
] | [] | [
"Disease variant",
"Hereditary spastic paraplegia",
"Neurodegeneration"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Enhanced | null | 56 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 31: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,394 | 6 |
ENSG00000107581 | EIF3A | Eukaryotic translation initiation factor 3 subunit A | [
"Q14152"
] | 10 | 119033670-119080823 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038315",
"HPA038316"
] | [
"EIF3",
"eIF3-p170",
"eIF3-theta",
"EIF3S10",
"KIAA0139",
"TIF32"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Protein biosynthesis"
] | [
"Initiation factor",
"RNA-binding"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 140 | Yes | No | Cluster 42: Non-specific - Vesicular transport | Cluster 42: Choroid plexus - Mitochondria | Cluster 52: Non-specific - Mitochondria | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,395 | 8 |
ENSG00000107593 | PKD2L1 | Polycystin 2 like 1, transient receptor potential cation channel | [
"Q9P0L9"
] | 10 | 100288149-100330264 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB022621",
"HPA070002"
] | [
"PCL",
"PKD2L",
"PKDL",
"TRPP3"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calcium channel",
"Ion channel"
] | [] | [
"Plasma membrane"
] | [
"Actin filaments",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 1 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 53: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 32: Retina & Lymphoid tissues - Signaling | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 3,396 | 8 |
ENSG00000107611 | CUBN | Cubilin | [
"O60494"
] | 10 | 16823966-17129811 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004133",
"HPA043854"
] | [
"gp280",
"IFCR",
"MGA1"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Cholesterol metabolism",
"Endocytosis",
"Lipid metabolism",
"Protein transport",
"Steroid metabolism",
"Sterol metabolism",
"Transport"
] | [
"Receptor"
] | [
"Disease variant"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Receptor"
] | null | Enhanced | null | 2 | null | null | null | Cluster 49: Hindbrain - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 72: Kidney - Transmembrane transport | Tissue enriched | Detected in many | 5 | Cancer enriched | Detected in some | 6 | Group enriched | Detected in some | 14 | Group enriched | Detected in many | 8 | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,397 | 4 |
ENSG00000107614 | TRDMT1 | TRNA aspartic acid methyltransferase 1 | [
"O14717"
] | 10 | 17137336-17202054 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009468",
"HPA036945",
"HPA036946"
] | [
"DNMT2",
"RNMT1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [
"Methyltransferase",
"RNA-binding",
"Transferase"
] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 52: Non-specific - Mitochondria | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 3,398 | 3 |
ENSG00000107625 | DDX50 | DExD-box helicase 50 | [
"Q9BQ39"
] | 10 | 68901286-68946847 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037388",
"HPA037389",
"HPA058196"
] | [
"GU2",
"GUB",
"MGC3199",
"RH-II/GuB"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Helicase",
"Hydrolase",
"RNA-binding"
] | [] | [
"Nucleoli"
] | [] | [] | [] | Enhanced | Approved | null | 86 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 55: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 7: Non-specific - Transcription | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,399 | 4 |
ENSG00000107643 | MAPK8 | Mitogen-activated protein kinase 8 | [
"P45983"
] | 10 | 48306639-48439360 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004463",
"CAB069396",
"HPA071800"
] | [
"JNK",
"JNK1",
"PRKM8",
"SAPK1"
] | [
"Cancer-related genes",
"Enzymes",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Biological rhythms"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 91 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 16: Non-specific - Transcription | Cluster 59: Leukemia - T-cell receptor | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 27: Cerebellum - Synaptic function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 3,400 | 3 |
ENSG00000107651 | SEC23IP | SEC23 interacting protein | [
"Q9Y6Y8"
] | 10 | 119892707-119944657 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038403",
"HPA043305"
] | [
"iPLA1Ã",
"iPLA1beta",
"p125",
"p125A"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Enhanced | Approved | null | 24 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 50: Non-specific - Nucleic acid binding | Cluster 52: Non-specific - Mitochondria | Cluster 8: Non-specific - Secretory pathway | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 3,401 | 3 |
ENSG00000107669 | ATE1 | Arginyltransferase 1 | [
"O95260"
] | 10 | 121709393-121928801 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038444",
"HPA057549"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Acyltransferase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 7 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 31: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,402 | 6 |
ENSG00000107672 | NSMCE4A | NSE4 homolog A, SMC5-SMC6 complex component | [
"Q9NXX6"
] | 10 | 121957091-121975217 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037459",
"HPA038412",
"HPA044872"
] | [
"bA500G22.3",
"C10orf86",
"FLJ20003",
"NSE4A"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA recombination",
"DNA repair"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 15 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 11: White matter - Signal transduction | Cluster 52: Non-specific - Mitochondria | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme"
] | 3,403 | 9 |
ENSG00000107679 | PLEKHA1 | Pleckstrin homology domain containing A1 | [
"Q9HB21"
] | 10 | 122374696-122432354 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002043",
"HPA064795"
] | [
"TAPP1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | Approved | null | 18 | null | null | Cluster 24: Non-specific - Transcription | Cluster 53: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,404 | 2 |
ENSG00000107731 | UNC5B | Unc-5 netrin receptor B | [
"Q8IZJ1"
] | 10 | 71212570-71302864 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA076687"
] | [
"p53RDL1",
"UNC5H2"
] | [
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Angiogenesis",
"Apoptosis"
] | [
"Developmental protein",
"Receptor"
] | [] | [] | [] | [] | [] | null | Approved | null | 5 | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 81: Squamous epithelium - Keratinization | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,406 | 8 |
ENSG00000107736 | CDH23 | Cadherin related 23 | [
"Q9H251"
] | 10 | 71396920-71815947 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA017232"
] | [
"CDHR23",
"DFNB12",
"USH1D"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Hearing",
"Sensory transduction",
"Vision"
] | [] | [
"Deafness",
"Disease variant",
"Non-syndromic deafness",
"Retinitis pigmentosa",
"Usher syndrome"
] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 49: Hindbrain - Mixed function | Cluster 11: Neuronal - Sensory perception | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 64: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 3,407 | 7 |
ENSG00000107738 | VSIR | V-set immunoregulatory receptor | [
"Q9H7M9"
] | 10 | 71747556-71773520 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"B7-H5",
"B7H5",
"C10orf54",
"Dies1",
"GI24",
"PD-1H",
"SISP1",
"VISTA"
] | [
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [] | [] | [] | [] | [] | null | null | null | 24 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 43: Hindbrain - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Testicular Germ Cell Tumor"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Testicular Germ Cell Tumor"
] | 3,408 | 4 |
ENSG00000107742 | SPOCK2 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2 | [
"Q92563"
] | 10 | 72059034-72089032 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044605"
] | [
"KIAA0275",
"testican-2"
] | [
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | null | Enhanced | null | 1 | null | null | Cluster 11: T-cells - Unknown function | Cluster 49: Hindbrain - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 4 | 0 | 4 | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,409 | 4 |
ENSG00000107745 | MICU1 | Mitochondrial calcium uptake 1 | [
"Q9BPX6"
] | 10 | 72367340-72626131 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037480",
"HPA057525"
] | [
"CALC",
"CBARA1",
"EFHA3",
"FLJ12684"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [] | [
"Allergen",
"Disease variant"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Approved | null | 9 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 35: Non-specific - DNA binding | Cluster 52: Non-specific - Mitochondria | Cluster 55: Myocytes - Oxidative muscle function | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 3,410 | 5 |
ENSG00000107758 | PPP3CB | Protein phosphatase 3 catalytic subunit beta | [
"P16298"
] | 10 | 73436433-73496024 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008233",
"HPA074370"
] | [
"CALNA2",
"CALNB",
"CNA2",
"PP2Bbeta"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Calmodulin-binding",
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm",
"Calyx"
] | [] | [] | Supported | Uncertain | null | 21 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 14: Neurons - Synaptic function | Cluster 52: Non-specific - Mitochondria | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 3,411 | 1 |
ENSG00000107771 | CCSER2 | Coiled-coil serine rich protein 2 | [
"Q9H7U1"
] | 10 | 84328586-84518521 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037481",
"HPA037482"
] | [
"FAM190B",
"KIAA1128"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 14 | null | null | Cluster 1: T-cells - Unknown function | Cluster 45: Non-specific - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 41: Striated muscle - Muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 13 | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,412 | 9 |
ENSG00000107789 | MINPP1 | Multiple inositol-polyphosphate phosphatase 1 | [
"Q9UNW1"
] | 10 | 87504875-87553461 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026859"
] | [
"MIPP"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase"
] | [
"Disease variant"
] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Approved | null | 6 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 23: Choroid plexus - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,414 | 8 |
ENSG00000107807 | TLX1 | T cell leukemia homeobox 1 | [
"P31314"
] | 10 | 101131300-101137789 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"HOX11",
"TCL3"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes",
"Proto-oncogene"
] | [] | [] | [] | [] | null | null | null | 9 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 5: Spleen - Immune response | Group enriched | Detected in some | 31 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma"
] | 3,417 | 7 |
ENSG00000107815 | TWNK | Twinkle mtDNA helicase | [
"Q96RR1"
] | 10 | 100987367-100994403 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002532"
] | [
"C10orf2",
"FLJ21832",
"IOSCA",
"PEO",
"PEO1",
"TWINKLE",
"TWINL"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"DNA replication"
] | [
"Helicase",
"Hydrolase",
"Isomerase"
] | [
"Deafness",
"Disease variant",
"Neurodegeneration",
"Neuropathy",
"Primary mitochondrial disease",
"Progressive external ophthalmoplegia"
] | [] | [] | [] | [] | null | Uncertain | null | 8 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 47: Endothelial cells - Vasculature | Cluster 52: Non-specific - Mitochondria | Cluster 17: Non-specific - RNA processing | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 3,418 | 8 |
ENSG00000107816 | LZTS2 | Leucine zipper tumor suppressor 2 | [
"Q9BRK4"
] | 10 | 100996618-101007836 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044956"
] | [
"KIAA1813",
"LAPSER1"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis",
"Wnt signaling pathway"
] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 256 | No | Yes | Cluster 24: Non-specific - Transcription | Cluster 11: White matter - Signal transduction | Cluster 33: Sarcoma - Muscle contraction | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 3,419 | 4 |
ENSG00000107819 | SFXN3 | Sideroflexin 3 | [
"Q9BWM7"
] | 10 | 101031234-101041241 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008028",
"HPA048105"
] | [
"SFX3",
"SLC56A3"
] | [
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Amino-acid transport",
"One-carbon metabolism",
"Transport"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Approved | null | 49 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 34: Non-specific - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,420 | 8 |
ENSG00000107821 | KAZALD1 | Kazal type serine peptidase inhibitor domain 1 | [
"Q96I82"
] | 10 | 101061989-101068131 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA011800"
] | [
"FKSG28",
"FKSG40"
] | [
"Predicted secreted proteins"
] | [
"Differentiation",
"Osteogenesis"
] | [
"Developmental protein"
] | [] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Developmental protein"
] | null | Uncertain | null | 1 | null | null | null | Cluster 32: Cerebral cortex - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 5: Spleen - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 3,421 | 7 |
ENSG00000107829 | FBXW4 | F-box and WD repeat domain containing 4 | [
"P57775"
] | 10 | 101610664-101695295 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043496"
] | [
"dactylin",
"Fbw4",
"SHFM3"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway",
"Wnt signaling pathway"
] | [
"Developmental protein"
] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Approved | null | 30 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 19: Astrocytes - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 7: Non-specific - Transcription | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 3,422 | 8 |
ENSG00000107831 | FGF8 | Fibroblast growth factor 8 | [
"P55075"
] | 10 | 101770109-101780371 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"AIGF"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [
"Differentiation"
] | [
"Developmental protein",
"Growth factor",
"Mitogen"
] | [
"Cancer-related genes",
"Disease variant",
"Hypogonadotropic hypogonadism",
"Kallmann syndrome"
] | [] | [] | [
"Secreted in other tissues"
] | [
"Growth factor"
] | null | null | null | 2 | null | null | null | Cluster 29: Forebrain - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 89: Adipocytes - Lipid metabolism | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enriched | Detected in single | 45 | Cancer enriched | Detected in some | 4 | Group enriched | Detected in some | 5 | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 3,423 | 8 |
ENSG00000107833 | NPM3 | Nucleophosmin/nucleoplasmin 3 | [
"O75607"
] | 10 | 101781325-101783446 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036295",
"HPA036296"
] | [] | [
"Predicted intracellular proteins"
] | [] | [
"Chaperone"
] | [] | [
"Nucleoli",
"Actin filaments",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 198 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 52: Non-specific - Mitochondria | Cluster 97: Non-specific - Cellular respiration | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 5 | 2 | 4 | [] | [
"Bladder Urothelial Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,424 | 3 |
ENSG00000107854 | TNKS2 | Tankyrase 2 | [
"Q9H2K2"
] | 10 | 91798426-91865475 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036606"
] | [
"ARTD6",
"PARP-5b",
"PARP-5c",
"PARP5B",
"PARP5C",
"pART6",
"TANK2",
"TNKL"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Wnt signaling pathway"
] | [
"Glycosyltransferase",
"Nucleotidyltransferase",
"Transferase"
] | [] | [
"Microtubules"
] | [] | [] | [] | Approved | null | null | 41 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 55: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 3,425 | 4 |
ENSG00000107859 | PITX3 | Paired like homeodomain 3 | [
"O75364"
] | 10 | 102230186-102241512 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"ASMD"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [
"Cataract",
"Disease variant"
] | [] | [] | [] | [] | null | null | null | 1 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 33: Sarcoma - Muscle contraction | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in single | 15 | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,426 | 6 |
ENSG00000107862 | GBF1 | Golgi brefeldin A resistant guanine nucleotide exchange factor 1 | [
"Q92538"
] | 10 | 102245371-102382899 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037759",
"HPA037760"
] | [
"ARF1GEF",
"KIAA0248"
] | [
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Protein transport",
"Transport"
] | [
"Guanine-nucleotide releasing factor"
] | [
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | Uncertain | null | 58 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 23: Choroid plexus - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 103: Non-specific - Basic cellular processes | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Lung Squamous Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | 3,427 | 5 |
ENSG00000107863 | ARHGAP21 | Rho GTPase activating protein 21 | [
"Q5T5U3"
] | 10 | 24583609-24723887 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036610",
"HPA057861"
] | [
"ARHGAP10",
"KIAA1424"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Plasma membrane",
"Cell Junctions"
] | [
"Actin filaments"
] | [] | [] | Approved | Approved | null | 24 | null | null | Cluster 31: T-cells - T-cell receptor | Cluster 11: White matter - Signal transduction | Cluster 52: Non-specific - Mitochondria | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,428 | 8 |
ENSG00000107864 | CPEB3 | Cytoplasmic polyadenylation element binding protein 3 | [
"Q8NE35"
] | 10 | 92046692-92291078 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA070942"
] | [
"KIAA0940"
] | [
"Predicted intracellular proteins"
] | [
"Translation regulation"
] | [
"Activator",
"Repressor",
"RNA-binding"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm",
"Plasma membrane",
"Midbody"
] | [] | [] | Approved | null | null | 1 | Yes | No | Cluster 42: Non-specific - Vesicular transport | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 51: Myeloma - Immunoglobulins | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 6 | 4 | 4 | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,429 | 7 |
ENSG00000107872 | FBXL15 | F-box and leucine rich repeat protein 15 | [
"Q9H469"
] | 10 | 102419189-102423136 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"Fbl15",
"FBXO37",
"MGC11279"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [] | [] | [] | [] | [] | null | null | null | 17 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 52: Non-specific - Mitochondria | Cluster 97: Non-specific - Cellular respiration | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 3,430 | 4 |
ENSG00000107882 | SUFU | SUFU negative regulator of hedgehog signaling | [
"Q9UMX1"
] | 10 | 102503972-102633535 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008700"
] | [
"PRO1280",
"SUFUH",
"SUFUXL"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Developmental protein"
] | [
"Cancer-related genes",
"Ciliopathy",
"Disease variant",
"Joubert syndrome",
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [
"Primary cilium"
] | [] | [] | Supported | Supported | null | 72 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 54: Immune cells - T cell receptor | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 3,432 | 3 |
ENSG00000107890 | ANKRD26 | Ankyrin repeat domain containing 26 | [
"Q9UPS8"
] | 10 | 26973793-27100494 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040654",
"HPA041460"
] | [
"KIAA1074",
"THC2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Approved | Approved | null | 11 | null | null | Cluster 41: Basophils - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,433 | 9 |
ENSG00000107897 | ACBD5 | Acyl-CoA binding domain containing 5 | [
"Q5T8D3"
] | 10 | 27168135-27243046 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011861",
"HPA012145"
] | [
"DKFZp434A2417",
"KIAA1996"
] | [
"Disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Autophagy",
"Transport"
] | [] | [
"Leukodystrophy"
] | [
"Peroxisomes"
] | [] | [] | [] | Enhanced | Enhanced | null | 16 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,434 | 2 |
ENSG00000107902 | LHPP | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase | [
"Q9H008"
] | 10 | 124461823-124617888 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA009163",
"HPA009269"
] | [
"HDHD2B"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [] | [
"Nuclear speckles",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 8 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 6: Non-specific - Immune response | Cluster 52: Non-specific - Mitochondria | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in all | 7 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,435 | 1 |
ENSG00000107929 | LARP4B | La ribonucleoprotein 4B | [
"Q92615"
] | 10 | 806933-931821 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036566",
"HPA042738"
] | [
"KIAA0217",
"LARP5"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Translation regulation"
] | [
"RNA-binding"
] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 68 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 24: Neurons - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 3,436 | 9 |
ENSG00000107937 | GTPBP4 | GTP binding protein 4 | [
"Q9BZE4"
] | 10 | 988434-1019932 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039618",
"HPA056468"
] | [
"CRFG",
"FLJ10686",
"FLJ10690",
"NGB",
"NOG1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis"
] | [] | [] | [
"Nucleoli",
"Nucleoli rim"
] | [
"Nuclear membrane"
] | [] | [] | Supported | Uncertain | null | 134 | No | No | Cluster 33: Non-specific - ATP binding | Cluster 21: Non-specific - Metabolism | Cluster 52: Non-specific - Mitochondria | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [
"Glioblastoma Multiforme"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,437 | 1 |
ENSG00000107938 | EDRF1 | Erythroid differentiation regulatory factor 1 | [
"Q3B7T1"
] | 10 | 125719515-125764143 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031820"
] | [
"C10orf137",
"DKFZp586F1019",
"FLJ21617"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [] | [
"Nucleoplasm"
] | [
"Centrosome",
"Cytosol"
] | [] | [] | Approved | null | null | 18 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 31: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 3,438 | 4 |
ENSG00000107949 | BCCIP | BRCA2 and CDKN1A interacting protein | [
"Q9P287"
] | 10 | 125823546-125853695 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038011"
] | [
"BCCIPalpha",
"TOK-1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"DNA damage",
"DNA repair"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | null | null | 31 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 55: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 6 | 0 | 6 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,439 | 5 |
ENSG00000107951 | MTPAP | Mitochondrial poly(A) polymerase | [
"Q9NVV4"
] | 10 | 30309801-30374448 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038620",
"HPA058232"
] | [
"FLJ10486",
"PAPD1",
"SPAX4",
"TENT6"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"Transcription"
] | [
"Nucleotidyltransferase",
"RNA-binding",
"Transferase"
] | [
"Disease variant",
"Neurodegeneration"
] | [
"Mitochondria"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | Supported | Approved | null | 36 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 2: Neurons - Nucleosome | Cluster 52: Non-specific - Mitochondria | Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,440 | 3 |
ENSG00000107954 | NEURL1 | Neuralized E3 ubiquitin protein ligase 1 | [
"O76050"
] | 10 | 103493705-103592546 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA044204"
] | [
"h-neu",
"neu-1",
"NEURL",
"RNF67"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Notch signaling pathway",
"Translation regulation",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Tumor suppressor"
] | [] | [] | [] | [] | null | Enhanced | null | 2 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 51: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 13 | 2 | 0 | 2 | [
"Colon Adenocarcinoma"
] | [
"Rectum Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 3,441 | 9 |
ENSG00000107957 | SH3PXD2A | SH3 and PX domains 2A | [
"Q5TCZ1"
] | 10 | 103594027-103855584 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA037922",
"HPA037923"
] | [
"FISH",
"KIAA0418",
"SH3MD1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Primary cilium transition zone",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 25 | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 69: Skin cancer - ECM organization | Cluster 103: Non-specific - Basic cellular processes | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 3,442 | 4 |
ENSG00000107959 | PITRM1 | Pitrilysin metallopeptidase 1 | [
"Q5JRX3"
] | 10 | 3137728-3172841 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006753",
"HPA006754"
] | [
"hMP1",
"KIAA1104",
"MP1",
"PreP"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Disease variant",
"Neurodegeneration"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 2 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 14: Neurons - Synaptic function | Cluster 52: Non-specific - Mitochondria | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 3,443 | 6 |
ENSG00000107960 | STN1 | STN1 subunit of CST complex | [
"Q9H668"
] | 10 | 103856806-103918332 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037924",
"HPA037925"
] | [
"bA541N10.2",
"FLJ22559",
"OBFC1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"DNA-binding"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 31 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 26: Oligodendrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 102: Non-specific - Mixed function | Cluster 81: Squamous epithelium - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,444 | 7 |
ENSG00000107968 | MAP3K8 | Mitogen-activated protein kinase kinase kinase 8 | [
"P41279"
] | 10 | 30434021-30461833 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005120",
"HPA017962"
] | [
"c-COT",
"COT",
"EST",
"ESTF",
"MEKK8",
"Tpl-2"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Immunity"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Proto-oncogene"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Supported | null | 17 | null | null | Cluster 32: Basophils - Transcription | Cluster 12: Non-specific - Vasculature | Cluster 55: Lymphoma - Immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 3,445 | 3 |
ENSG00000108001 | EBF3 | EBF transcription factor 3 | [
"Q9H4W6"
] | 10 | 129835233-129973053 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA061169"
] | [
"COE3",
"DKFZp667B0210"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Approved | null | null | 1 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 64: Connective tissue cells - ECM organization | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 3,447 | 4 |
ENSG00000108010 | GLRX3 | Glutaredoxin 3 | [
"O76003"
] | 10 | 130136391-130184521 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA028941"
] | [
"bA500G10.4",
"GLRX4",
"GRX3",
"GRX4",
"PICOT",
"TXNL2"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 118 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 45: Non-specific - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 17: Non-specific - RNA processing | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 6 | 0 | 6 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 3,448 | 5 |
ENSG00000108018 | SORCS1 | Sortilin related VPS10 domain containing receptor 1 | [
"Q8WY21"
] | 10 | 106573663-107164706 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011948"
] | [] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,449 | 5 |
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