ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000112306
RPS12
Ribosomal protein S12
[ "P25398" ]
6
132814569-132817564
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006124", "HPA006365" ]
[ "S12" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[]
[ "Cytosol" ]
[ "Golgi apparatus", "Vesicles" ]
[]
[]
Supported
Approved
null
118
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 7: Non-specific - Ribosome
Cluster 25: Non-specific - Ribosome
Cluster 15: Non-specific - Protein processing
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
4,003
1
ENSG00000112308
C6orf62
Chromosome 6 open reading frame 62
[ "Q9GZU0" ]
6
24704861-24719998
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA030564", "HPA030566" ]
[ "DKFZP564G182", "FLJ12619", "XTP12" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Supported
null
1
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 39: Astrocytes - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 32: Retina & Lymphoid tissues - Signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
4,004
2
ENSG00000112309
B3GAT2
Beta-1,3-glucuronyltransferase 2
[ "Q9NPZ5" ]
6
70856679-70957060
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA012059" ]
[ "GlcAT-S" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Transferase" ]
[]
[]
[]
[]
[]
null
Uncertain
null
9
null
null
null
Cluster 28: Oligodendrocytes - Mixed function
Cluster 11: Neuronal - Sensory perception
Cluster 109: Neurons - Neuronal signaling
Cluster 46: Brain & retina - Neuronal signaling
Group enriched
Detected in many
11
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
19
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,005
1
ENSG00000112312
GMNN
Geminin DNA replication inhibitor
[ "O75496" ]
6
24774931-24786099
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB011458", "CAB047327", "CAB047328", "HPA049977", "HPA054597" ]
[ "Gem" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cell cycle" ]
[ "DNA replication inhibitor" ]
[ "Cancer-related genes", "Disease variant", "Dwarfism" ]
[ "Nucleoplasm" ]
[ "Basal body", "Cytosol" ]
[]
[]
Supported
Enhanced
null
34
Yes
No
Cluster 12: Non-specific - Mitochondrial translation
Cluster 19: Astrocytes - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 8: Pancreas - Proteolysis
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
4,006
2
ENSG00000112319
EYA4
EYA transcriptional coactivator and phosphatase 4
[ "O95677" ]
6
133240514-133532128
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA004805", "HPA038771", "HPA038772" ]
[ "CMD1J", "DFNA10" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "Transcription", "Transcription regulation" ]
[ "Activator", "Chromatin regulator", "Developmental protein", "Hydrolase", "Protein phosphatase" ]
[ "Cardiomyopathy", "Deafness", "Disease variant", "Non-syndromic deafness" ]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Enhanced
null
10
No
null
null
Cluster 3: Choroid plexus - Cilium
Cluster 5: Rhabdoid - Unknown function
Cluster 36: Skeletal myocytes - Muscle excitation & contraction
Cluster 30: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
4,007
5
ENSG00000112320
SOBP
Sine oculis binding protein homolog
[ "A7XYQ1" ]
6
107490106-107661306
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA029242" ]
[ "FLJ10159" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Approved
Uncertain
null
3
null
null
Cluster 18: Non-specific - Translation
Cluster 51: Neurons - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 91: Pituicytes/FSC - Homeostasis & neuron support
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
4,008
4
ENSG00000112333
NR2E1
Nuclear receptor subfamily 2 group E member 1
[ "Q9Y466" ]
6
108166022-108188805
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036954", "HPA055642" ]
[ "TLL", "TLX", "XTLL" ]
[ "Nuclear receptors", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "Developmental protein", "DNA-binding", "Receptor", "Repressor" ]
[]
[ "Nuclear bodies" ]
[]
[]
[]
Approved
Uncertain
null
8
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 72: Neuronal - Signal transduction
Cluster 11: Muller glia cells - Retinal homeostasis
Cluster 46: Brain & retina - Neuronal signaling
Group enriched
Detected in some
56
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in some
9
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
4,009
4
ENSG00000112335
SNX3
Sorting nexin 3
[ "O60493" ]
6
108211222-108261246
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "Grd19" ]
[ "Disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]
[ "Protein transport", "Transport" ]
[]
[ "Microphthalmia" ]
[]
[]
[]
[]
null
null
null
47
null
null
Cluster 29: Non-specific - Unknown function
Cluster 14: Neurons - Synaptic function
Cluster 28: Non-specific - Nuclear processes
Cluster 82: Dendritic cells - Antigen presentation
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Breast Invasive Carcinoma", "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
4,010
4
ENSG00000112337
SLC17A2
Solute carrier family 17 member 2
[ "O00624" ]
6
25912754-25930691
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA038270" ]
[ "NPT3" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Sodium transport", "Symport", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
null
Cluster 18: Liver cancer - Metabolism
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in single
166
Not detected
Not detected
null
Cancer enriched
Detected in some
6
Cell type enriched
Detected in some
14
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
4,011
3
ENSG00000112339
HBS1L
HBS1 like translational GTPase
[ "Q9Y450" ]
6
134960378-135103056
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA029728", "HPA029729" ]
[ "DKFZp434g247", "EF-1a", "eRF3c", "ERFS", "HBS1", "HSPC276", "KIAA1038" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Protein biosynthesis", "Translation regulation" ]
[ "Elongation factor", "Hydrolase" ]
[]
[ "Nuclear bodies", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
33
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 28: Oligodendrocytes - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 80: Oligodendrocytes - Myelination
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
4,012
7
ENSG00000112343
TRIM38
Tripartite motif containing 38
[ "O00635" ]
6
25962802-25991231
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031685" ]
[ "RNF15", "RORET" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Immunity", "Innate immunity", "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Centrosome" ]
[ "Plasma membrane", "Cell Junctions" ]
[]
[]
Approved
Approved
null
22
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 20: Macrophages & Microglia - Immune response
Cluster 71: Lymphoma - Inflammatory response
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 66: Lymphoid tissue - Immune response
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Papillary Cell Carcinoma" ]
4,013
3
ENSG00000112357
PEX7
Peroxisomal biogenesis factor 7
[ "O00628" ]
6
136822564-136913934
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049202" ]
[ "PTS2R", "RD" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]
[ "Protein transport", "Transport" ]
[]
[ "Cataract", "Deafness", "Disease variant", "Ichthyosis", "Peroxisome biogenesis disorder", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata" ]
[ "Nucleoplasm", "Vesicles" ]
[]
[]
[]
Supported
Uncertain
null
24
null
null
Cluster 33: Non-specific - ATP binding
Cluster 25: Non-specific - Transcription
Cluster 28: Non-specific - Nuclear processes
Cluster 97: Non-specific - Cellular respiration
Cluster 38: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,014
8
ENSG00000112365
ZBTB24
Zinc finger and BTB domain containing 24
[ "O43167" ]
6
109460632-109483239
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA017872", "HPA049003" ]
[ "BIF1", "KIAA0441", "PATZ2", "ZNF450" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[ "Disease variant" ]
[ "Nucleoplasm" ]
[ "Cytokinetic bridge", "Centrosome" ]
[]
[]
Approved
Uncertain
null
67
Yes
No
Cluster 3: Non-specific - Nuclear processes
Cluster 9: Non-specific - Receptor signaling
Cluster 28: Non-specific - Nuclear processes
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 40: Non-specific - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
4,015
3
ENSG00000112367
FIG4
FIG4 phosphoinositide 5-phosphatase
[ "Q92562" ]
6
109690609-109878098
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB017823", "HPA068859" ]
[ "ALS11", "CMT4J", "dJ249I4.1", "hSac3", "KIAA0274", "SAC3" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Hydrolase" ]
[ "Amyotrophic lateral sclerosis", "Charcot-Marie-Tooth disease", "Disease variant", "Neurodegeneration", "Neuropathy" ]
[ "Vesicles", "Lipid droplets" ]
[]
[]
[]
Supported
Approved
null
11
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 21: Non-specific - Metabolism
Cluster 28: Non-specific - Nuclear processes
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
4,016
8
ENSG00000112378
PERP
P53 apoptosis effector related to PMP22
[ "Q96FX8" ]
6
138088505-138107419
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA022269" ]
[ "dJ496H19.1", "KCP1", "KRTCAP1", "PIGPC1", "THW" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Apoptosis", "Cell adhesion" ]
[]
[ "Disease variant", "Palmoplantar keratoderma" ]
[]
[]
[]
[]
null
Enhanced
null
7
null
null
Cluster 32: Basophils - Transcription
Cluster 42: Choroid plexus - Mitochondria
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 58: Skin - Keratinization
Group enriched
Detected in all
4
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
4
4
0
4
[]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
4,017
4
ENSG00000112379
ARFGEF3
ARFGEF family member 3
[ "Q5TH69" ]
6
138161939-138344663
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036350" ]
[ "BIG3", "C6orf92", "dJ171N11.1", "KIAA1244", "PPP1R33" ]
[ "Predicted intracellular proteins" ]
[]
[ "Guanine-nucleotide releasing factor" ]
[]
[]
[]
[]
[]
null
Uncertain
null
3
null
null
null
Cluster 34: Non-specific - Mixed function
Cluster 60: Prostate cancer - Unknown function
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 70: Non-specific - Protein processing
Tissue enhanced
Detected in many
null
Group enriched
Detected in many
4
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
4,018
2
ENSG00000112394
SLC16A10
Solute carrier family 16 member 10
[ "Q8TF71" ]
6
111087503-111231194
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016860" ]
[ "MCT10", "TAT1" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[]
[]
[ "Vesicles", "Cell Junctions" ]
[]
[]
[]
Supported
Approved
null
4
null
null
Cluster 31: T-cells - T-cell receptor
Cluster 23: Choroid plexus - Mixed function
Cluster 32: Non-specific - Cell proliferation
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 63: Non-specific - Basic cellular processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in all
4
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
4,019
5
ENSG00000112406
HECA
Hdc homolog, cell cycle regulator
[ "Q9UBI9" ]
6
139135080-139180802
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA012581", "HPA042313" ]
[ "dJ225E12.1", "HDC", "HDCL", "hHDC" ]
[ "Predicted intracellular proteins" ]
[]
[ "Developmental protein" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 33: Non-specific - ATP binding
Cluster 19: Astrocytes - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 58: Skin - Keratinization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
4,020
7
ENSG00000112414
ADGRG6
Adhesion G protein-coupled receptor G6
[ "Q86SQ4" ]
6
142301854-142446266
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA017346" ]
[ "FLJ14937", "GPR126" ]
[ "Disease related genes", "G-protein coupled receptors", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[ "Disease variant" ]
[]
[]
[]
[]
null
Approved
null
null
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
4,021
8
ENSG00000112419
PHACTR2
Phosphatase and actin regulator 2
[ "O75167" ]
6
143536845-143831185
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA031719", "HPA031720", "HPA031725" ]
[ "C6orf56", "KIAA0680" ]
[ "Predicted intracellular proteins" ]
[]
[ "Actin-binding", "Protein phosphatase inhibitor" ]
[]
[ "Golgi apparatus" ]
[ "Plasma membrane" ]
[]
[]
Approved
Approved
null
7
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 42: Choroid plexus - Mitochondria
Cluster 64: Connective tissue cells - ECM organization
Cluster 101: Choroid plexus epithelial cells - Ion transport
Cluster 43: Placenta - Pregnancy hormone signaling
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Uterine Corpus Endometrial Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
4,022
8
ENSG00000112425
EPM2A
EPM2A glucan phosphatase, laforin
[ "O95278" ]
6
145382535-145736023
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA053643", "HPA055468" ]
[ "LD", "LDE" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Autophagy", "Carbohydrate metabolism", "Glycogen metabolism" ]
[ "Hydrolase", "Protein phosphatase" ]
[ "Disease variant", "Epilepsy", "Glycogen storage disease", "Neurodegeneration" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
null
null
18
null
null
Cluster 18: Non-specific - Translation
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 46: Lymphoma - Humoral immune response
Cluster 95: Tuft cells - Chemosensory signaling
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
4
2
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Stomach Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma", "Stomach Adenocarcinoma" ]
4,023
6
ENSG00000112462
OR12D3
Olfactory receptor family 12 subfamily D member 3
[ "Q9UGF7" ]
6
29373423-29375291
Evidence at transcript level
No human protein/transcript evidence
Evidence at transcript level
Evidence at transcript level
[]
[ "hs6M1-27" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
null
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,024
7
ENSG00000112473
SLC39A7
Solute carrier family 39 member 7
[ "Q92504" ]
6
33200305-33204439
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA053999" ]
[ "D6S2244E", "H2-KE4", "HKE4", "KE4", "RING5", "ZIP7" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport", "Zinc transport" ]
[]
[ "Disease variant" ]
[ "Endoplasmic reticulum" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Approved
null
39
null
null
Cluster 24: Non-specific - Transcription
Cluster 44: Non-specific - Mixed function
Cluster 63: Non-specific - Protein processing
Cluster 78: Plasma cells - Antibody production & ER-stress response
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]
4,025
5
ENSG00000112486
CCR6
C-C motif chemokine receptor 6
[ "P51684" ]
6
167111807-167139141
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB006820", "HPA014488" ]
[ "BN-1", "CD196", "CKR-L3", "CMKBR6", "DCR2", "DRY-6", "GPR-CY4", "GPR29", "STRL22" ]
[ "CD markers", "G-protein coupled receptors", "Human disease related genes", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Approved
null
8
null
null
Cluster 16: Non-specific - Cell proliferation
null
Cluster 18: Liver cancer - Metabolism
Cluster 102: Non-specific - Mixed function
Cluster 18: Lymphoid tissue - Immune response
Tissue enriched
Detected in some
5
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Group enriched
Detected in many
4
3
0
3
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Lung Adenocarcinoma" ]
4,026
7
ENSG00000112494
UNC93A
Unc-93 homolog A
[ "Q86WB7" ]
6
167271169-167316014
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035729" ]
[ "dJ366N23.1", "dJ366N23.2" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
1
null
null
null
null
Cluster 10: Ciliated cells - Ion channel activity
Cluster 64: Renal epithelial cells - Ion transport & homeostasis
Cluster 58: Skin - Keratinization
Group enriched
Detected in some
10
Group enriched
Detected in some
5
Cancer enhanced
Detected in many
null
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
4,027
7
ENSG00000112499
SLC22A2
Solute carrier family 22 member 2
[ "O15244" ]
6
160171061-160277638
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA008549", "CAB068236", "CAB068237" ]
[ "OCT2" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
4
null
null
null
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 15: Kidney cancer - Membrane components
Cluster 88: Proximal tubular cells - Transmembrane transport
Cluster 72: Kidney - Transmembrane transport
Tissue enriched
Detected in some
80
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
8
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
4,028
6
ENSG00000112511
PHF1
PHD finger protein 1
[ "O43189" ]
6
33410399-33416453
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031038", "HPA076579" ]
[ "MTF2L2", "PCL1", "TDRD19C" ]
[ "Disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "Repressor" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
76
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 30: White matter - Myelination
Cluster 28: Non-specific - Nuclear processes
Cluster 102: Non-specific - Mixed function
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,029
7
ENSG00000112514
CUTA
CutA divalent cation tolerance homolog
[ "O60888" ]
6
33416442-33418317
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB016787", "HPA064369", "HPA070199" ]
[ "ACHAP", "C6orf82" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[ "Plasma membrane", "Focal adhesion sites" ]
[]
[ "Secreted to blood" ]
[ "No annotated function" ]
Approved
Approved
null
4
null
null
Cluster 39: T-cells - T-cell receptor
Cluster 21: Non-specific - Metabolism
Cluster 28: Non-specific - Nuclear processes
Cluster 67: Plasma cells - Plasma cell differentiation
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
4,030
5
ENSG00000112530
PACRG
Parkin coregulated
[ "Q96M98" ]
6
162727132-163315500
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA066293" ]
[ "FLJ32724", "Glup", "HAK005771", "PARK2CRG" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Mid piece", "Principal piece", "End piece" ]
[ "Mitochondria" ]
[]
[]
Supported
Enhanced
null
4
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 46: Brainstem - Mixed function
Cluster 56: Non-specific - Sensory perception
Cluster 50: Renal epithelial cells - Ion transport and pH regulation
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enriched
Detected in many
5
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
1
0
1
[ "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
4,031
7
ENSG00000112531
QKI
QKI, KH domain containing RNA binding
[ "Q96PU8" ]
6
163414000-163578592
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019123", "CAB022602" ]
[ "QK3" ]
[ "Cancer-related genes", "Predicted intracellular proteins" ]
[ "Differentiation", "mRNA processing", "mRNA splicing", "mRNA transport", "Translation regulation", "Transport" ]
[ "Developmental protein", "DNA-binding", "RNA-binding" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Enhanced
Supported
51
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 13: Oligodendrocytes - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 55: Myocytes - Oxidative muscle function
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enriched
Detected in all
5
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,032
4
ENSG00000112539
C6orf118
Chromosome 6 open reading frame 118
[ "Q5T5N4" ]
6
165279664-165309605
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA029787", "HPA029789" ]
[ "bA85G2.1", "MGC23884" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mitochondria" ]
[]
[]
[]
Uncertain
Approved
null
null
null
null
null
Cluster 3: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 56: Ciliated tissues - Cilium organization
Group enriched
Detected in some
5
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,033
4
ENSG00000112541
PDE10A
Phosphodiesterase 10A
[ "Q9Y233" ]
6
165327287-165988117
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB045998", "HPA047200" ]
[]
[ "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Allosteric enzyme", "Hydrolase" ]
[ "Disease variant", "FDA approved drug targets" ]
[]
[]
[]
[]
null
Supported
null
1
null
null
null
Cluster 33: Neurons - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 72: Kidney - Transmembrane transport
Low tissue specificity
Detected in some
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
4,034
2
ENSG00000112559
MDFI
MyoD family inhibitor
[ "Q99750" ]
6
41636882-41654244
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA049973" ]
[ "I-mfa" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation" ]
[ "Developmental protein" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
347
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 12: Bone cancer - Neuronal signaling
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma", "Skin Cutaneous Melanoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma", "Skin Cutaneous Melanoma" ]
4,035
3
ENSG00000112561
TFEB
Transcription factor EB
[ "P19484" ]
6
41683978-41736259
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA067082" ]
[ "bHLHe35", "TCFEB" ]
[ "Cancer-related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Adaptive immunity", "Autophagy", "Immunity", "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[ "Cancer-related genes" ]
[ "Cytosol" ]
[]
[]
[]
Supported
null
null
9
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 11: White matter - Signal transduction
Cluster 55: Lymphoma - Immune response
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
6
2
0
2
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
4,036
3
ENSG00000112562
SMOC2
SPARC related modular calcium binding 2
[ "Q9H3U7" ]
6
168441151-168673445
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "SMAP2" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted to extracellular matrix" ]
[ "No annotated function" ]
null
null
null
1
null
null
null
Cluster 42: Choroid plexus - Mitochondria
Cluster 70: DU4475 - Unknown function
Cluster 94: Gonadal somatic cells - Mixed function
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Bladder Urothelial Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
4,037
9
ENSG00000112576
CCND3
Cyclin D3
[ "P30281" ]
6
41934934-42050357
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB000116", "HPA042871" ]
[]
[ "Cancer-related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Transcription", "Transcription regulation" ]
[ "Cyclin" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
55
null
Yes
Cluster 41: Basophils - Unknown function
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 6: Leukemia - Signal transduction
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Thyroid Carcinoma" ]
[]
[ "Thyroid Carcinoma" ]
4,038
3
ENSG00000112578
BYSL
Bystin like
[ "Q13895" ]
6
41921499-41933046
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031217", "HPA031219" ]
[ "Enp1" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Ribosome biogenesis" ]
[]
[]
[ "Nucleoli", "Nucleoli rim", "Mitotic chromosome" ]
[ "Nucleoplasm" ]
[]
[]
Enhanced
Enhanced
null
288
Yes
No
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 27: Non-specific - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 17: Non-specific - RNA processing
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
2
2
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]
4,039
2
ENSG00000112584
FAM120B
Family with sequence similarity 120B
[ "Q96EK7" ]
6
170290703-170407067
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA037518", "HPA037519" ]
[ "CCPG", "KIAA1838", "PGCC1", "SAN1" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Transcription", "Transcription regulation" ]
[ "Activator" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Uncertain
null
10
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 26: Oligodendrocytes - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,040
7
ENSG00000112599
GUCA1B
Guanylate cyclase activator 1B
[ "Q9UMX6" ]
6
42183284-42194956
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA055479" ]
[ "GCAP2", "RP48" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]
[ "Sensory transduction", "Vision" ]
[]
[ "Disease variant", "Retinitis pigmentosa" ]
[ "Microtubules", "Primary cilium" ]
[ "Nucleoplasm", "Nuclear membrane", "Basal body" ]
[]
[]
Approved
Enhanced
null
null
null
null
null
Cluster 13: Oligodendrocytes - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in many
79
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
37
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
4,042
5
ENSG00000112619
PRPH2
Peripherin 2
[ "P23942" ]
6
42696598-42722597
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029458" ]
[ "CACD2", "rd2", "RDS", "RP7", "TSPAN22" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Cell adhesion", "Sensory transduction", "Vision" ]
[]
[ "Cone-rod dystrophy", "Disease variant", "Retinitis pigmentosa" ]
[]
[]
[]
[]
null
Enhanced
null
2
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 1: Neuronal - Visual perception
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in many
48
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Group enriched
Detected in many
13
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,043
4
ENSG00000112640
PPP2R5D
Protein phosphatase 2 regulatory subunit B'delta
[ "Q14738" ]
6
42984553-43012342
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029045", "HPA029046" ]
[ "B56D", "B56delta" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Intellectual disability" ]
[ "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Approved
null
26
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 28: Non-specific - Nuclear processes
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
4,045
9
ENSG00000112651
MRPL2
Mitochondrial ribosomal protein L2
[ "Q5T653" ]
6
43054029-43059438
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA007455", "HPA064814" ]
[ "CGI-22", "MRP-L14", "RPML14" ]
[ "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[]
[ "Mitochondria" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Approved
null
133
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 37: Neurons - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 15: Non-specific - Protein processing
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Bladder Urothelial Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
4,046
5
ENSG00000112655
PTK7
Protein tyrosine kinase 7 (inactive)
[ "Q13308" ]
6
43076307-43161719
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003222" ]
[ "CCK4" ]
[ "Enzymes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins" ]
[ "Cell adhesion", "Wnt signaling pathway" ]
[ "Receptor" ]
[]
[ "Plasma membrane", "Cytosol" ]
[ "Vesicles" ]
[ "Secreted to blood" ]
[ "Receptor" ]
Approved
Approved
null
22
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 36: Choroid plexus - Mixed function
Cluster 32: Non-specific - Cell proliferation
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in some
10
1
0
1
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
4,047
9
ENSG00000112658
SRF
Serum response factor
[ "P11831" ]
6
43171269-43181506
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001819", "CAB005416" ]
[ "MCM1" ]
[ "Essential proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Supported
null
33
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 51: Neurons - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
0
0
0
[]
[]
[]
4,048
7
ENSG00000112659
CUL9
Cullin 9
[ "Q8IWT3" ]
6
43182184-43224587
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA016434", "HPA052004" ]
[ "H7AP1", "KIAA0708", "PARC" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
11
No
No
Cluster 33: Non-specific - ATP binding
Cluster 32: Cerebral cortex - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
19
Not detected in immune cells
Not detected
null
3
0
3
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
4,049
3
ENSG00000112667
DNPH1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
[ "O43598" ]
6
43225629-43229481
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029675", "HPA029676" ]
[ "C6orf108", "dJ330M21.3", "rcl" ]
[ "Predicted intracellular proteins" ]
[ "Nucleotide metabolism" ]
[ "Glycosidase", "Hydrolase" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
5
No
No
Cluster 33: Non-specific - ATP binding
Cluster 36: Choroid plexus - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 72: Kidney - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
4,050
5
ENSG00000112679
DUSP22
Dual specificity phosphatase 22
[ "Q9NRW4" ]
6
291630-351355
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA031394" ]
[ "JKAP", "JSP1", "MKPX", "VHX" ]
[ "Enzymes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Immunity" ]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Nucleoplasm", "Vesicles" ]
[]
[]
[]
Approved
Approved
null
3
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
4,051
6
ENSG00000112685
EXOC2
Exocyst complex component 2
[ "Q96KP1" ]
6
485154-693139
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA032093" ]
[ "FLJ11026", "Sec5", "SEC5L1" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "RAS pathway related proteins", "Transporters" ]
[ "Exocytosis", "Protein transport", "Transport" ]
[]
[ "Disease variant", "Intellectual disability", "Neurodegeneration" ]
[ "Vesicles" ]
[]
[]
[]
Approved
null
null
37
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 30: White matter - Myelination
Cluster 71: Lymphoma - Inflammatory response
Cluster 7: Non-specific - Transcription
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,052
8
ENSG00000112695
COX7A2
Cytochrome c oxidase subunit 7A2
[ "P14406" ]
6
75237675-75250323
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "COX7AL", "COXVIIa-L" ]
[ "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[ "Oxidoreductase" ]
[]
[]
[]
[]
[]
null
null
null
11
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 21: Non-specific - Metabolism
Cluster 28: Non-specific - Nuclear processes
Cluster 97: Non-specific - Cellular respiration
Cluster 1: Choroid plexus - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
4,053
2
ENSG00000112697
TMEM30A
Transmembrane protein 30A
[ "Q9NV96" ]
6
75252924-75284948
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA014561" ]
[ "C6orf67", "CDC50A", "FLJ10856" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Lipid transport", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
25
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 21: Non-specific - Metabolism
Cluster 64: Connective tissue cells - ECM organization
Cluster 17: Non-specific - RNA processing
Cluster 73: Brain - Neuronal signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
4,054
8
ENSG00000112699
GMDS
GDP-mannose 4,6-dehydratase
[ "O60547" ]
6
1623806-2245605
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031528" ]
[ "GMD", "SDR3E1" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Lyase" ]
[]
[]
[]
[]
[]
null
Enhanced
null
7
null
null
Cluster 33: Non-specific - ATP binding
Cluster 23: Choroid plexus - Mixed function
Cluster 2: Mucus-secreting cells - Unknown function
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 17: Intestine - Digestion
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]
4,055
4
ENSG00000112701
SENP6
SUMO specific peptidase 6
[ "Q9GZR1" ]
6
75601509-75718281
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA024376" ]
[ "KIAA0797", "SUSP1" ]
[ "Enzymes", "Essential proteins", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Hydrolase", "Protease", "Thiol protease" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
10
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 16: Non-specific - Transcription
Cluster 28: Non-specific - Nuclear processes
Cluster 7: Non-specific - Transcription
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Uterine Corpus Endometrial Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
4,056
2
ENSG00000112706
IMPG1
Interphotoreceptor matrix proteoglycan 1
[ "Q17R60" ]
6
75921114-76072678
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA027142", "HPA030332", "HPA030333" ]
[ "GP147", "IPM150", "SPACR" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Heparin-binding", "Receptor" ]
[ "Disease variant", "Retinitis pigmentosa" ]
[ "Plasma membrane", "Microtubules", "Mid piece", "Principal piece", "End piece" ]
[]
[ "Secreted in other tissues" ]
[ "Receptor" ]
Uncertain
Enhanced
null
null
null
null
null
Cluster 34: Non-specific - Mixed function
Cluster 11: Neuronal - Sensory perception
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in some
93
Cancer enhanced
Detected in single
null
Not detected
Not detected
null
Group enriched
Detected in some
23
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,057
7
ENSG00000112715
VEGFA
Vascular endothelial growth factor A
[ "P15692" ]
6
43770184-43786487
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005429", "CAB039240", "HPA069116", "CAB069907" ]
[ "VEGF", "VEGF-A", "VPF" ]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins"...
[ "Angiogenesis", "Differentiation" ]
[ "Developmental protein", "Growth factor", "Heparin-binding", "Mitogen" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[]
[]
[ "Secreted to blood" ]
[ "Growth factor" ]
null
Supported
null
24
null
null
null
Cluster 42: Choroid plexus - Mitochondria
Cluster 15: Kidney cancer - Membrane components
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
6
0
6
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
4,058
4
ENSG00000112739
PRPF4B
Pre-mRNA processing factor 4B
[ "Q13523" ]
6
4021267-4064983
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA020638" ]
[ "KIAA0536", "PR4H", "Prp4" ]
[ "Enzymes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Supported
Approved
null
162
null
null
null
Cluster 55: Non-specific - Transcription
Cluster 56: Non-specific - Sensory perception
Cluster 17: Non-specific - RNA processing
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Head and Neck Squamous Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
4,059
3
ENSG00000112742
TTK
TTK protein kinase
[ "P33981" ]
6
80003887-80042527
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB010166", "CAB013229", "HPA058657" ]
[ "CT96", "MPH1", "MPS1", "MPS1L1" ]
[ "Enzymes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase", "Tyrosine-protein kinase" ]
[]
[ "Cytosol" ]
[ "Nucleoli" ]
[]
[]
Approved
Enhanced
null
17
null
Yes
null
null
Cluster 28: Non-specific - Nuclear processes
Cluster 27: Non-specific - Cell proliferation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Group enriched
Detected in many
6
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
6
6
3
[]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
4,060
3
ENSG00000112759
SLC29A1
Solute carrier family 29 member 1 (Augustine blood group)
[ "Q99808" ]
6
44219553-44234142
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA012384" ]
[ "ENT1" ]
[ "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
15
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 24: Neurons - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in all
26
1
0
1
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
4,061
7
ENSG00000112761
CCN6
Cellular communication network factor 6
[ "O95389" ]
6
112054075-112069686
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA064196" ]
[ "WISP-3", "WISP3" ]
[ "Disease related genes", "Human disease related genes", "Predicted secreted proteins" ]
[]
[ "Growth factor" ]
[ "Disease variant" ]
[ "Mitochondria" ]
[]
[ "Secreted to extracellular matrix" ]
[ "Growth factor" ]
Supported
null
null
3
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 50: Epididymis - Male reproductive secretion
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in some
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,062
5
ENSG00000112763
BTN2A1
Butyrophilin subfamily 2 member A1
[ "Q7KYR7" ]
6
26457904-26476621
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019208" ]
[ "BT2.1", "BTF1", "BTN2.1" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Plasma membrane" ]
[]
[]
[]
Approved
Approved
null
2
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 25: Non-specific - Transcription
Cluster 28: Non-specific - Nuclear processes
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,063
3
ENSG00000112769
LAMA4
Laminin subunit alpha 4
[ "Q16363" ]
6
112107931-112254939
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA015693", "CAB078156" ]
[ "LAMA3" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Cell adhesion" ]
[]
[ "Cardiomyopathy", "Disease variant" ]
[ "Plasma membrane", "Cytosol" ]
[]
[ "Secreted to extracellular matrix" ]
[ "Cell adhesion" ]
Approved
Enhanced
null
3
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 69: Skin cancer - ECM organization
Cluster 89: Adipocytes - Lipid metabolism
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
4,064
6
ENSG00000112773
TENT5A
Terminal nucleotidyltransferase 5A
[ "Q96IP4" ]
6
81491439-81752774
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA051067", "HPA067140" ]
[ "C6orf37", "FAM46A", "FLJ20037" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Nucleotidyltransferase", "Transferase" ]
[ "Disease variant", "Osteogenesis imperfecta" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Uncertain
null
14
null
null
Cluster 29: Non-specific - Unknown function
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 15: Bone marrow - Innate immune response
Group enriched
Detected in all
4
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
4,065
9
ENSG00000112782
CLIC5
Chloride intracellular channel 5
[ "Q9NZA1" ]
6
45880827-46080348
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA074371" ]
[ "DFNB102" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]
[ "Hearing", "Ion transport", "Sensory transduction", "Transport", "Vision" ]
[ "Chloride channel", "Ion channel", "Oxidoreductase", "Voltage-gated channel" ]
[ "Deafness", "Non-syndromic deafness" ]
[ "Plasma membrane" ]
[ "Nuclear speckles" ]
[]
[]
Supported
null
null
1
null
null
Cluster 1: T-cells - Unknown function
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 15: Kidney cancer - Membrane components
Cluster 57: Podocytes - Glomerular filtration
Cluster 62: Skeletal muscle - Muscle contraction
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
4
Immune cell enhanced
Detected in some
null
2
0
2
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
4,066
9
ENSG00000112787
FBRSL1
Fibrosin like 1
[ "Q9HCM7" ]
12
132489551-132585188
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049880" ]
[ "KIAA1545" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Approved
Enhanced
null
12
null
null
Cluster 29: Non-specific - Unknown function
Cluster 15: Non-specific - Transcription
Cluster 38: Non-specific - Transcription
Cluster 82: Dendritic cells - Antigen presentation
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
3
0
3
[ "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
[ "Prostate Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma", "Prostate Adenocarcinoma", "Rectum Adenocarcinoma" ]
4,067
3
ENSG00000112796
ENPP5
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5
[ "Q9UJA9" ]
6
46159185-46170980
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016902" ]
[]
[ "Predicted membrane proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Cytosol" ]
[ "Nucleoplasm" ]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Approved
Enhanced
null
3
null
null
Cluster 1: T-cells - Unknown function
Cluster 1: Neurons - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 10: Epididymal principal cells - Sperm maturation microenvironment
Cluster 22: Epididymis - Mixed function
Tissue enriched
Detected in many
5
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
4,068
3
ENSG00000112799
LY86
Lymphocyte antigen 86
[ "O95711" ]
6
6588108-6654983
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB025000", "HPA044895" ]
[ "dJ80N2.1", "MD-1" ]
[ "Predicted secreted proteins" ]
[ "Immunity", "Inflammatory response", "Innate immunity" ]
[]
[]
[]
[]
[ "Secreted to blood" ]
[ "Immunity" ]
null
Approved
null
119
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 74: Microglia - Neuroimmunity & neuroinflammation
Cluster 18: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Group enriched
Detected in some
4
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
4,069
1
ENSG00000112812
PRSS16
Serine protease 16
[ "Q9NQE7" ]
6
27247701-27256624
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "TSSP" ]
[ "Enzymes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Hydrolase", "Protease", "Serine protease" ]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "Enzyme" ]
null
null
null
null
null
null
Cluster 24: Non-specific - Transcription
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 80: Thymus - Adaptive immune response
Tissue enriched
Detected in many
57
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
0
1
[ "Ovary Serous Cystadenocarcinoma" ]
[]
[ "Ovary Serous Cystadenocarcinoma" ]
4,070
9
ENSG00000112818
MEP1A
Meprin A subunit alpha
[ "Q16819" ]
6
46793389-46839778
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB025163", "HPA029416" ]
[ "PPHA" ]
[ "Enzymes", "Plasma proteins", "Predicted membrane proteins" ]
[]
[ "Hydrolase", "Metalloprotease", "Protease" ]
[]
[]
[]
[]
[]
null
Enhanced
null
1
null
null
null
null
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 7: Small intestine - Absorption and Digestion
Tissue enriched
Detected in some
101
Group enriched
Detected in some
13
Group enriched
Detected in some
5
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
4,071
6
ENSG00000112837
TBX18
T-box transcription factor 18
[ "O95935" ]
6
84687351-84764598
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006807" ]
[]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding", "Repressor" ]
[ "Disease variant" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
null
null
5
null
null
null
Cluster 42: Choroid plexus - Mitochondria
Cluster 64: Connective tissue cells - ECM organization
Cluster 22: Non-specific - Basic cellular functions
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,072
2
ENSG00000112851
ERBIN
Erbb2 interacting protein
[ "Q96RT1" ]
5
65883128-66082546
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA048606", "HPA059863" ]
[ "ERBB2IP", "LAP2" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane", "Cell Junctions" ]
[]
[]
[]
Supported
Approved
null
42
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 13: Oligodendrocytes - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 3: Oligodendrocytes - Myelination
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
4,073
2
ENSG00000112852
PCDHB2
Protocadherin beta 2
[ "Q9Y5E7" ]
5
141094606-141098703
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA007548" ]
[ "PCDH-BETA2" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Enhanced
null
1
null
null
null
Cluster 34: Non-specific - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 57: Testis - Spermatogenesis
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Stomach Adenocarcinoma" ]
[ "Stomach Adenocarcinoma" ]
4,074
1
ENSG00000112855
HARS2
Histidyl-tRNA synthetase 2, mitochondrial
[ "P49590" ]
5
140691430-140699305
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA035941", "HPA075303" ]
[ "HARSL", "HARSR", "HO3" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Protein biosynthesis" ]
[ "Aminoacyl-tRNA synthetase", "Ligase" ]
[ "Deafness", "Disease variant" ]
[ "Mitochondria" ]
[]
[]
[]
Approved
Approved
null
62
null
null
Cluster 25: Non-specific - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 7: Non-specific - Transcription
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,075
2
ENSG00000112874
NUDT12
Nudix hydrolase 12
[ "Q9BQG2" ]
5
103548855-103562790
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045449" ]
[ "DKFZP761I172" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[]
[]
[]
[]
[]
null
Supported
null
8
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 65: Non-specific - Unknown function
Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in single
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,076
1
ENSG00000112877
CEP72
Centrosomal protein 72
[ "Q9P209" ]
5
612340-667168
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA058235", "HPA074879" ]
[ "FLJ10565", "KIAA1519" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Centriolar satellite", "Centrosome" ]
[ "Basal body" ]
[]
[]
Supported
Approved
null
33
null
null
Cluster 24: Non-specific - Transcription
Cluster 34: Non-specific - Mixed function
Cluster 29: Non-specific - Unknown function
Cluster 61: Schwann cells & Melanocytes - Mixed function
Cluster 67: Testis - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
1
0
1
[]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe" ]
4,077
7
ENSG00000112902
SEMA5A
Semaphorin 5A
[ "Q13591" ]
5
9035033-9546075
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA004632" ]
[ "SEMAF", "semF" ]
[ "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Differentiation", "Neurogenesis" ]
[ "Developmental protein" ]
[]
[]
[]
[]
[]
null
Approved
null
null
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 29: Forebrain - Mixed function
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 14: Oligodendrocyte progenitor cells - Development & myelination
Cluster 72: Kidney - Transmembrane transport
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
12
2
2
1
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
4,079
8
ENSG00000112936
C7
Complement C7
[ "P10643" ]
5
40909492-41020216
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA001465" ]
[]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted secreted proteins" ]
[ "Complement alternate pathway", "Complement pathway", "Cytolysis", "Immunity", "Innate immunity" ]
[]
[ "Cancer-related genes", "Disease variant" ]
[]
[]
[ "Secreted to blood" ]
[ "Complement pathway" ]
null
Approved
null
1
null
null
null
Cluster 8: Immune cells - Immune response
Cluster 44: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 4: Adrenal gland - Steroid metabolism
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in some
12
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Rectum Adenocarcinoma" ]
4,080
5
ENSG00000112941
TENT4A
Terminal nucleotidyltransferase 4A
[ "Q5XG87" ]
5
6713432-6757044
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045487", "HPA046742" ]
[ "LAK-1", "PAPD7", "POLK", "POLS", "TRF4", "TRF4-1" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "mRNA processing" ]
[ "Nucleotidyltransferase", "Transferase" ]
[]
[ "Nucleoplasm" ]
[ "Nuclear membrane", "Golgi apparatus" ]
[]
[]
Supported
Enhanced
null
1
null
null
Cluster 30: Non-specific - DNA binding
Cluster 2: Neurons - Nucleosome
Cluster 29: Non-specific - Unknown function
Cluster 82: Dendritic cells - Antigen presentation
Cluster 15: Bone marrow - Innate immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in single
null
3
0
3
[ "Lung Squamous Cell Carcinoma" ]
[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Lung Adenocarcinoma", "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
4,081
1
ENSG00000112964
GHR
Growth hormone receptor
[ "P10912" ]
5
42423439-42721878
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045339", "HPA057705" ]
[ "GHBP" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Predicted membrane proteins", "Predicted secreted proteins" ]
[ "Endocytosis" ]
[ "Receptor" ]
[ "Disease variant", "Dwarfism", "FDA approved drug targets" ]
[ "Plasma membrane", "Cytosol", "Cytoplasmic bodies" ]
[]
[ "Secreted to blood" ]
[ "Receptor" ]
Supported
Enhanced
null
31
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 3: Rhabdoid - Membrane components
Cluster 89: Adipocytes - Lipid metabolism
Cluster 45: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
4
Not detected in immune cells
Not detected
null
4
4
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Thyroid Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]
4,082
8
ENSG00000112972
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1
[ "Q01581" ]
5
43287470-43313512
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB032907", "HPA036913", "HPA036914" ]
[ "HMGCS" ]
[ "Enzymes", "Essential proteins", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cholesterol biosynthesis", "Cholesterol metabolism", "Lipid biosynthesis", "Lipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism" ]
[ "Transferase" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Supported
Approved
null
15
No
No
Cluster 29: Non-specific - Unknown function
Cluster 49: Hindbrain - Mixed function
Cluster 66: Non-specific - Mitochondria
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 45: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,083
4
ENSG00000112977
DAP
Death associated protein
[ "P51397" ]
5
10679230-10761234
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA029456" ]
[ "DAP1" ]
[ "Predicted intracellular proteins" ]
[ "Apoptosis", "Autophagy", "Translation regulation" ]
[]
[]
[ "Vesicles", "Mitochondria" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Uncertain
null
3
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 8: Immune cells - Immune response
Cluster 29: Non-specific - Unknown function
Cluster 4: Breast lactating luminal cells - Lactation
Cluster 8: Pancreas - Proteolysis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
4,084
6
ENSG00000112981
NME5
NME/NM23 family member 5
[ "P56597" ]
5
138115175-138139443
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044555", "HPA058103" ]
[ "nm23-H5", "RSPH23" ]
[ "Human disease related genes", "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[ "Developmental protein", "Hydrolase" ]
[ "Ciliopathy", "Primary ciliary dyskinesia" ]
[ "Cytosol" ]
[ "Plasma membrane", "Primary cilium" ]
[]
[]
Approved
Enhanced
null
10
null
null
null
Cluster 17: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
4,085
8
ENSG00000112984
KIF20A
Kinesin family member 20A
[ "O95235" ]
5
138178719-138187723
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036909", "HPA036910" ]
[ "MKLP2", "RAB6KIFL" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[ "Motor protein" ]
[ "Cardiomyopathy", "Disease variant" ]
[ "Nucleoplasm", "Cytokinetic bridge", "Cleavage furrow", "Mitotic spindle" ]
[]
[]
[]
Approved
Approved
null
26
Yes
Yes
Cluster 16: Non-specific - Cell proliferation
Cluster 12: Non-specific - Vasculature
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 27: Non-specific - Cell proliferation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Group enriched
Detected in some
12
6
6
3
[]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
4,087
3
ENSG00000112996
MRPS30
Mitochondrial ribosomal protein S30
[ "Q9NP92" ]
5
44808947-44820428
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA018686", "HPA021149" ]
[ "PAP", "PDCD9" ]
[ "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[]
[]
[]
[]
[]
null
Approved
null
93
null
null
Cluster 16: Non-specific - Cell proliferation
Cluster 53: Neurons - Mixed function
Cluster 29: Non-specific - Unknown function
Cluster 17: Non-specific - RNA processing
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
4,089
5
ENSG00000113013
HSPA9
Heat shock protein family A (Hsp70) member 9
[ "P38646" ]
5
138553756-138575675
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000898", "CAB005219" ]
[ "GRP75", "HSPA9B", "mot-2", "mthsp75", "PBP74" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Chaperone", "Hydrolase" ]
[ "Disease variant", "Dwarfism" ]
[ "Mitochondria" ]
[]
[]
[]
Supported
Supported
null
118
null
null
Cluster 33: Non-specific - ATP binding
Cluster 21: Non-specific - Metabolism
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 103: Non-specific - Basic cellular processes
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Colon Adenocarcinoma", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
4,090
5
ENSG00000113048
MRPS27
Mitochondrial ribosomal protein S27
[ "Q92552" ]
5
72214953-72321717
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA071751" ]
[ "KIAA0264" ]
[ "Essential proteins", "Predicted intracellular proteins", "Ribosomal proteins" ]
[ "Translation regulation" ]
[ "Ribonucleoprotein", "Ribosomal protein", "RNA-binding", "rRNA-binding", "tRNA-binding" ]
[]
[ "Mitochondria" ]
[ "Nucleoli" ]
[]
[]
Supported
Approved
null
122
null
null
Cluster 33: Non-specific - ATP binding
Cluster 21: Non-specific - Metabolism
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,091
4
ENSG00000113068
PFDN1
Prefoldin subunit 1
[ "O60925" ]
5
140245035-140303113
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006499" ]
[ "PFD1" ]
[ "Essential proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Chaperone" ]
[]
[ "Plasma membrane", "Cytosol" ]
[ "Nucleoli" ]
[]
[]
Approved
Approved
null
58
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 45: Non-specific - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 83: Epicardial mesothelial cells - Basic cellular functions
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in all
31
Low immune cell specificity
Detected in all
null
5
0
5
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
4,092
2
ENSG00000113070
HBEGF
Heparin binding EGF like growth factor
[ "Q99075" ]
5
140332843-140346603
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA019793", "HPA053243" ]
[ "DTR", "DTS", "HEGFL" ]
[ "Predicted membrane proteins", "Predicted secreted proteins" ]
[]
[ "Growth factor", "Heparin-binding", "Receptor" ]
[]
[ "Golgi apparatus" ]
[ "Vesicles" ]
[ "Secreted to blood" ]
[ "Growth factor" ]
Approved
Uncertain
null
16
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 11: White matter - Signal transduction
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
5
2
0
2
[]
[ "Head and Neck Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
4,093
3
ENSG00000113088
GZMK
Granzyme K
[ "P49863" ]
5
55024256-55034570
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA059953", "HPA063181", "HPA065895" ]
[ "PRSS", "TRYP2" ]
[ "Enzymes", "Predicted secreted proteins" ]
[]
[ "Hydrolase", "Protease", "Serine protease" ]
[]
[ "Golgi apparatus" ]
[]
[ "Secreted to blood" ]
[ "Enzyme" ]
Approved
Enhanced
null
3
null
null
Cluster 1: T-cells - Unknown function
null
Cluster 6: Leukemia - Signal transduction
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 18: Lymphoid tissue - Immune response
Tissue enriched
Detected in many
9
Not detected
Not detected
null
Cancer enhanced
Detected in all
null
Group enriched
Detected in some
14
Immune cell enhanced
Detected in many
null
3
0
3
[ "Breast Invasive Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
4,096
4
ENSG00000113108
APBB3
Amyloid beta precursor protein binding family B member 3
[ "O95704" ]
5
140558268-140564781
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA005571", "HPA076196" ]
[ "FE65L2" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nuclear bodies", "Actin filaments" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
17
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
4
0
4
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
4,098
7
ENSG00000113119
TMCO6
Transmembrane and coiled-coil domains 6
[ "Q96DC7" ]
5
140639435-140645408
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA037473", "HPA037474" ]
[ "FLJ39769", "PRO1580" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mitochondria" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Uncertain
null
7
No
No
Cluster 35: Neutrophils - Protein binding
Cluster 20: Macrophages & Microglia - Immune response
Cluster 47: Leukemia - Hemostasis
Cluster 18: Adrenal cortex cells - Steroidogensis
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
4,099
1
ENSG00000113161
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
[ "P04035" ]
5
75336329-75364001
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA008338", "CAB016797", "CAB078688" ]
[]
[ "Enzymes", "Essential proteins", "FDA approved drug targets", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Cholesterol biosynthesis", "Cholesterol metabolism", "Lipid biosynthesis", "Lipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism" ]
[ "Oxidoreductase" ]
[ "Disease variant", "FDA approved drug targets", "Limb-girdle muscular dystrophy" ]
[]
[]
[]
[]
null
Supported
null
10
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 24: Neurons - Mixed function
Cluster 66: Non-specific - Mitochondria
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
4,102
1
ENSG00000113163
CERT1
Ceramide transporter 1
[ "Q9Y5P4" ]
5
75356345-75512138
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035645", "HPA042608" ]
[ "CERT", "COL4A3BP", "GPBP", "STARD11" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Lipid transport", "Transport" ]
[]
[ "Disease variant", "Intellectual disability" ]
[ "Golgi apparatus" ]
[ "Nucleoplasm" ]
[]
[]
Enhanced
Enhanced
null
19
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 55: Non-specific - Transcription
Cluster 69: Skin cancer - ECM organization
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,103
3
ENSG00000113194
FAF2
Fas associated factor family member 2
[ "Q96CS3" ]
5
176447628-176510074
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA065968", "HPA071246", "HPA073828" ]
[ "ETEA", "KIAA0887", "UBXD8", "UBXN3B" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Unfolded protein response" ]
[]
[]
[ "Lipid droplets" ]
[ "Endoplasmic reticulum" ]
[]
[]
Enhanced
Approved
null
75
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 1: Neurons - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
4,104
2
ENSG00000113196
HAND1
Heart and neural crest derivatives expressed 1
[ "O96004" ]
5
154474972-154478227
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA040925", "HPA075313" ]
[ "bHLHa27", "eHand", "Hxt", "Thing1" ]
[ "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nuclear membrane", "Nuclear bodies" ]
[]
[]
Approved
Uncertain
null
5
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 108: Fibroblasts - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in some
null
Group enriched
Detected in some
8
Cancer enhanced
Detected in some
null
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,105
4
ENSG00000113205
PCDHB3
Protocadherin beta 3
[ "Q9Y5E6" ]
5
141100473-141103827
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA050296" ]
[ "PCDH-BETA3" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Supported
Uncertain
null
83
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 57: Testis - Spermatogenesis
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,106
9
ENSG00000113209
PCDHB5
Protocadherin beta 5
[ "Q9Y5E4" ]
5
141135206-141138615
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA013191", "HPA067473" ]
[ "DKFZp586B0217", "PCDH-BETA5" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[]
[ "Plasma membrane" ]
[ "Vesicles" ]
[]
[]
Approved
Approved
null
4
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 15: Kidney cancer - Membrane components
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 65: Brain - Transcription
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in many
4
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Stomach Adenocarcinoma" ]
[ "Stomach Adenocarcinoma" ]
4,107
5
ENSG00000113211
PCDHB6
Protocadherin beta 6
[ "Q9Y5E3" ]
5
141150057-141153287
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA029566", "HPA075308" ]
[ "PCDH-BETA6" ]
[ "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 15: Kidney cancer - Membrane components
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in some
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in some
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,108
3
ENSG00000113212
PCDHB7
Protocadherin beta 7
[ "Q9Y5E2" ]
5
141172644-141176383
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA059271" ]
[ "PCDH-BETA7" ]
[ "Plasma proteins", "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
19
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 15: Kidney cancer - Membrane components
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
4
Group enriched
Detected in some
6
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,109
1
ENSG00000113231
PDE8B
Phosphodiesterase 8B
[ "O95263" ]
5
77210449-77428256
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036911", "HPA036912" ]
[]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[ "Cushing syndrome", "Disease variant" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Supported
null
null
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 32: Non-specific - Cell proliferation
Cluster 22: Non-specific - Basic cellular functions
Cluster 33: Thyroid gland - Tissue development
Tissue enriched
Detected in many
4
Low cancer specificity
Detected in some
null
Cancer enriched
Detected in many
6
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
4,110
6
ENSG00000113240
CLK4
CDC like kinase 4
[ "Q9HAZ1" ]
5
178602664-178630615
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA043746" ]
[]
[ "Enzymes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase", "Tyrosine-protein kinase" ]
[]
[ "Actin filaments" ]
[]
[]
[]
Approved
Approved
null
11
No
No
Cluster 24: Non-specific - Transcription
Cluster 31: Non-specific - Transcription
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,111
6
ENSG00000113249
HAVCR1
Hepatitis A virus cellular receptor 1
[ "Q96D42" ]
5
157026742-157069396
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA007173", "CAB075697" ]
[ "CD365", "HAVCR", "HAVCR-1", "KIM1", "TIM-1", "TIM1", "TIMD1" ]
[ "CD markers", "Predicted membrane proteins" ]
[ "Host-virus interaction" ]
[ "Host cell receptor for virus entry", "Receptor" ]
[]
[ "Vesicles" ]
[]
[]
[]
Uncertain
Uncertain
null
2
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 48: Non-specific - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 88: Proximal tubular cells - Transmembrane transport
Cluster 72: Kidney - Transmembrane transport
Group enriched
Detected in some
5
Cancer enriched
Detected in many
4
Group enriched
Detected in many
13
Cell type enriched
Detected in some
5
Immune cell enhanced
Detected in some
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,113
7