ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000114315 | HES1 | Hes family bHLH transcription factor 1 | [
"Q14469"
] | 3 | 194136148-194138732 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA066929"
] | [
"bHLHb39",
"FLJ20408",
"HES-1",
"HRY"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 20 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 58: Skin - Keratinization | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 8 | 2 | 0 | 2 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 4,229 | 5 |
ENSG00000114316 | USP4 | Ubiquitin specific peptidase 4 | [
"Q13107"
] | 3 | 49277144-49340712 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018499",
"HPA074006"
] | [
"UNP",
"Unph"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [
"Vesicles",
"Basal body",
"Cytosol"
] | [] | [] | Supported | Approved | null | 38 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 23: Choroid plexus - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 6 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 4,230 | 5 |
ENSG00000114331 | ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | [
"Q15057"
] | 3 | 195274745-195443044 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034807",
"HPA034808"
] | [
"CENTB2",
"CNT-B2",
"KIAA0041"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Endosomes"
] | [] | [] | [] | Approved | Supported | null | 7 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 31: Non-specific - Transcription | Cluster 63: Non-specific - Protein processing | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 4,231 | 7 |
ENSG00000114346 | ECT2 | Epithelial cell transforming 2 | [
"Q9H8V3"
] | 3 | 172750682-172821474 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036363",
"HPA053261"
] | [
"ARHGEF31"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Differentiation",
"Neurogenesis",
"Protein transport",
"Transport"
] | [
"Guanine-nucleotide releasing factor"
] | [
"Oncogene"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | null | null | 67 | No | Yes | Cluster 32: Basophils - Transcription | Cluster 37: Neurons - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,232 | 3 |
ENSG00000114349 | GNAT1 | G protein subunit alpha transducin 1 | [
"P11488"
] | 3 | 50191610-50197696 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045393"
] | [
"CSNBAD3"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Sensory transduction",
"Vision"
] | [
"Transducer"
] | [
"Congenital stationary night blindness",
"Disease variant"
] | [
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | [] | Approved | Enhanced | null | null | null | null | null | Cluster 9: Non-specific - Receptor signaling | Cluster 1: Neuronal - Visual perception | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in some | 944 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 16 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,233 | 8 |
ENSG00000114353 | GNAI2 | G protein subunit alpha i2 | [
"P04899"
] | 3 | 50226292-50259362 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007704"
] | [
"GIP",
"GNAI2B"
] | [
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division"
] | [
"Transducer"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm",
"Plasma membrane",
"Basal body"
] | [] | [] | Supported | Approved | null | 38 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 39: Astrocytes - Mixed function | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 5: Spleen - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,234 | 8 |
ENSG00000114354 | TFG | Trafficking from ER to golgi regulator | [
"Q92734"
] | 3 | 100709295-100748964 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019473",
"HPA052206"
] | [
"FLJ36137",
"SPG57",
"TF6"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"ER-Golgi transport",
"Transport"
] | [] | [
"Cancer-related genes",
"Disease variant",
"Hereditary spastic paraplegia",
"Neurodegeneration",
"Neuropathy",
"Proto-oncogene"
] | [
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 63 | No | No | Cluster 42: Non-specific - Vesicular transport | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,235 | 6 |
ENSG00000114374 | USP9Y | Ubiquitin specific peptidase 9 Y-linked | [
"O00507"
] | Y | 12537650-12860839 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA057687"
] | [
"AZFA",
"DFFRY"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Vesicles"
] | [] | [] | [] | Uncertain | null | null | 2 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 5: Non-specific - Mixed function | Cluster 60: Prostate cancer - Unknown function | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 4,236 | 7 |
ENSG00000114378 | HYAL1 | Hyaluronidase 1 | [
"Q12794"
] | 3 | 50299890-50312381 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002112"
] | [
"HYAL-1",
"LUCA1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Glycosidase",
"Hydrolase"
] | [
"Disease variant",
"Mucopolysaccharidosis"
] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Uncertain | null | null | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 18: Liver cancer - Metabolism | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 4,237 | 7 |
ENSG00000114383 | TUSC2 | Tumor suppressor 2, mitochondrial calcium regulator | [
"O75896"
] | 3 | 50320027-50328251 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030116"
] | [
"C3orf11",
"FUS1",
"PAP",
"PDAP2"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [] | [
"Cancer-related genes",
"Tumor suppressor"
] | [
"Cytosol"
] | [
"Vesicles"
] | [] | [] | Approved | null | null | 36 | null | null | Cluster 19: Eosinophils - Unknown function | Cluster 1: Neurons - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,238 | 4 |
ENSG00000114388 | NPRL2 | NPR2 like, GATOR1 complex subunit | [
"Q8WTW4"
] | 3 | 50347330-50350826 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038196",
"HPA038197"
] | [
"NPR2",
"NPR2L",
"TUSC4"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [
"Disease variant",
"Epilepsy",
"Tumor suppressor"
] | [] | [] | [] | [] | null | Approved | null | 40 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 27: Non-specific - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,239 | 1 |
ENSG00000114391 | RPL24 | Ribosomal protein L24 | [
"P83731"
] | 3 | 101681091-101686733 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051653"
] | [
"L24"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 133 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,240 | 5 |
ENSG00000114395 | CYB561D2 | Cytochrome b561 family member D2 | [
"O14569"
] | 3 | 50350845-50358460 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA071862"
] | [
"101F6",
"TSP10"
] | [
"Enzymes",
"Predicted membrane proteins"
] | [
"Electron transport",
"Transport"
] | [
"Translocase"
] | [] | [] | [] | [] | [] | null | Approved | null | 16 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 8: Non-specific - Basic cellular processes | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,241 | 8 |
ENSG00000114405 | C3orf14 | Chromosome 3 open reading frame 14 | [
"Q9HBI5"
] | 3 | 62319015-62336213 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA048286"
] | [
"HT021"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 8 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 14: Neurons - Synaptic function | Cluster 27: Breast cancer - Unknown function | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,242 | 8 |
ENSG00000114416 | FXR1 | FMR1 autosomal homolog 1 | [
"P51114"
] | 3 | 180868141-180982753 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018246",
"HPA055475"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Myogenesis",
"Spermatogenesis"
] | [
"Developmental protein",
"RNA-binding"
] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 131 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 28: Oligodendrocytes - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 75: Non-specific - Chaperones and protein folding | Cluster 30: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 6 | 4 | 4 | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Prostate Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Prostate Adenocarcinoma"
] | 4,243 | 1 |
ENSG00000114423 | CBLB | Cbl proto-oncogene B | [
"Q13191"
] | 3 | 105655461-105869552 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018327",
"HPA019880"
] | [
"Cbl-b",
"RNF56"
] | [
"Cancer-related genes",
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 57 | null | null | Cluster 15: NK-cells - Unknown function | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 64: Connective tissue cells - ECM organization | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 4,244 | 7 |
ENSG00000114439 | BBX | BBX high mobility group box domain containing | [
"Q8WY36"
] | 3 | 107522936-107811339 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006049",
"HPA050646"
] | [
"HBP2",
"HSPC339",
"MDS001"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 6 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 11: White matter - Signal transduction | Cluster 63: Non-specific - Protein processing | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,245 | 4 |
ENSG00000114446 | IFT57 | Intraflagellar transport 57 | [
"Q9NWB7"
] | 3 | 108160812-108222435 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035514",
"HPA035515"
] | [
"ESRRBL1",
"FLJ10147",
"HIPPI",
"MHS4R2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [
"Ciliopathy"
] | [
"Golgi apparatus",
"Primary cilium",
"Basal body",
"Mid piece"
] | [
"Primary cilium transition zone",
"Centriolar satellite",
"Cytosol"
] | [] | [] | Approved | Supported | null | 68 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 23: Choroid plexus - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,246 | 6 |
ENSG00000114450 | GNB4 | G protein subunit beta 4 | [
"Q9HAV0"
] | 3 | 179396088-179451476 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB018383",
"CAB018737",
"HPA040736",
"HPA074924"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [] | [
"Transducer"
] | [
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Plasma membrane"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Supported | null | 22 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 20: Macrophages & Microglia - Immune response | Cluster 21: Lymphoma - Adaptive immune response | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 4,247 | 9 |
ENSG00000114455 | HHLA2 | HERV-H LTR-associating 2 | [
"Q9UM44"
] | 3 | 108296529-108378285 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055478"
] | [
"B7-H5",
"B7-H7",
"B7H7",
"B7y"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 13 | null | null | null | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Tissue enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 4 | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 4,248 | 1 |
ENSG00000114480 | GBE1 | 1,4-alpha-glucan branching enzyme 1 | [
"Q04446"
] | 3 | 81489703-81761645 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038073",
"HPA038074",
"HPA038075"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Glycogen biosynthesis"
] | [
"Glycosyltransferase",
"Transferase"
] | [
"Disease variant",
"Glycogen storage disease",
"Neuropathy"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 1 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | 4,250 | 9 |
ENSG00000114491 | UMPS | Uridine monophosphate synthetase | [
"P11172"
] | 3 | 124730433-124749273 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036178",
"HPA036179"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Pyrimidine biosynthesis"
] | [
"Decarboxylase",
"Glycosyltransferase",
"Lyase",
"Multifunctional enzyme",
"Transferase"
] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 3 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 34: Non-specific - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,252 | 4 |
ENSG00000114503 | NCBP2 | Nuclear cap binding protein subunit 2 | [
"P52298"
] | 3 | 196935402-196942594 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044850",
"HPA062483"
] | [
"Cbc2",
"CBP20",
"NIP1"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"mRNA processing",
"mRNA splicing",
"mRNA transport",
"Nonsense-mediated mRNA decay",
"RNA-mediated gene silencing",
"Translation regulation",
"Transport"
] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Basal body",
"Cytosol"
] | [] | [] | Supported | Supported | null | 33 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 39: Astrocytes - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 17: Non-specific - RNA processing | Cluster 36: Brain & Liver - Signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Prostate Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Prostate Adenocarcinoma"
] | 4,253 | 9 |
ENSG00000114520 | SNX4 | Sorting nexin 4 | [
"O95219"
] | 3 | 125446650-125520202 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005709"
] | [
"ATG24B"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 26 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 55: Non-specific - Transcription | Cluster 63: Non-specific - Protein processing | Cluster 7: Non-specific - Transcription | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Rectum Adenocarcinoma"
] | 4,254 | 4 |
ENSG00000114529 | C3orf52 | Chromosome 3 open reading frame 52 | [
"Q5BVD1"
] | 3 | 112086335-112131004 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008119",
"HPA011968"
] | [
"FLJ23186",
"TTMP"
] | [
"Predicted membrane proteins"
] | [] | [] | [
"Disease variant",
"Hypotrichosis"
] | [] | [] | [] | [] | null | Uncertain | null | 104 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,255 | 4 |
ENSG00000114541 | FRMD4B | FERM domain containing 4B | [
"Q9Y2L6"
] | 3 | 69168782-69542583 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA009705"
] | [
"GRSP1",
"KIAA1013"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Centriolar satellite"
] | [
"Nucleoplasm",
"Golgi apparatus"
] | [] | [] | Approved | Uncertain | Supported | 2 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 6: Leukemia - Signal transduction | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 81: Squamous epithelium - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 4,256 | 9 |
ENSG00000114544 | SLC41A3 | Solute carrier family 41 member 3 | [
"Q96GZ6"
] | 3 | 126006357-126101561 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045847"
] | [
"FLJ20473"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Approved | null | 9 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 63: Non-specific - Protein processing | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,257 | 8 |
ENSG00000114547 | ROPN1B | Rhophilin associated tail protein 1B | [
"Q9BZX4"
] | 3 | 125969160-125983454 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052530"
] | [] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Principal piece"
] | [] | [] | [] | Approved | Supported | null | 1 | null | null | null | Cluster 9: Non-specific - Receptor signaling | Cluster 69: Skin cancer - ECM organization | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in some | 6 | Cancer enriched | Detected in some | 5 | Cancer enriched | Detected in some | 4 | Group enriched | Detected in many | 13 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 4,258 | 1 |
ENSG00000114554 | PLXNA1 | Plexin A1 | [
"Q9UIW2"
] | 3 | 126982693-127037389 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007499",
"CAB012483"
] | [
"NOV",
"PLXN1"
] | [
"Disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Centrosome",
"Basal body"
] | [] | [] | Approved | Uncertain | null | 42 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 81: Alveolar cells - Lung function | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,259 | 4 |
ENSG00000114626 | ABTB1 | Ankyrin repeat and BTB domain containing 1 | [
"Q969K4"
] | 3 | 127672935-127680926 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035022",
"HPA035023"
] | [
"BPOZ",
"Btb3",
"BTBD21",
"EF1ABP"
] | [
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Elongation factor"
] | [] | [
"Cytosol"
] | [
"Nucleoli"
] | [] | [] | Supported | Uncertain | null | 17 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in all | 5 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,261 | 2 |
ENSG00000114631 | PODXL2 | Podocalyxin like 2 | [
"Q9NZ53"
] | 3 | 127629185-127672802 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB024934",
"HPA042265"
] | [
"endoglycan",
"PODLX2"
] | [
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Golgi apparatus"
] | [
"Vesicles"
] | [] | [] | Approved | Approved | null | 1 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 4,262 | 8 |
ENSG00000114638 | UPK1B | Uroplakin 1B | [
"O75841"
] | 3 | 119173517-119205143 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031799",
"HPA031800"
] | [
"TSPAN20",
"UPK1"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 41 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 4,263 | 6 |
ENSG00000114646 | CSPG5 | Chondroitin sulfate proteoglycan 5 | [
"O95196"
] | 3 | 47562238-47580792 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA071779",
"HPA076601"
] | [
"NGC"
] | [
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Differentiation",
"Growth regulation",
"Neurogenesis"
] | [
"Developmental protein"
] | [] | [
"Golgi apparatus",
"Vesicles",
"Plasma membrane",
"Cytosol"
] | [] | [
"Secreted in brain"
] | [
"Developmental protein"
] | Approved | Enhanced | null | 5 | null | No | null | Cluster 51: Neurons - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 78: Brain - Neuronal signaling | Group enriched | Detected in some | 20 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 18 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Ovary Serous Cystadenocarcinoma"
] | 4,264 | 1 |
ENSG00000114648 | KLHL18 | Kelch like family member 18 | [
"O94889"
] | 3 | 47282917-47346816 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035027",
"HPA035028"
] | [
"FLJ13703",
"KIAA0795"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis",
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Approved | Approved | null | 7 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 14: Neurons - Synaptic function | Cluster 8: Non-specific - Basic cellular processes | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 40: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,265 | 1 |
ENSG00000114650 | SCAP | SREBF chaperone | [
"Q12770"
] | 3 | 47413681-47477126 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA004713"
] | [
"KIAA0199"
] | [
"Predicted membrane proteins"
] | [
"Cholesterol metabolism",
"Lipid metabolism",
"Steroid metabolism",
"Sterol metabolism"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 37 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 8: Non-specific - Basic cellular processes | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 4,266 | 2 |
ENSG00000114654 | EFCC1 | EF-hand and coiled-coil domain containing 1 | [
"Q9HA90"
] | 3 | 129001304-129040742 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA042798",
"HPA050888",
"HPA076069"
] | [
"C3orf73",
"CCDC48",
"FLJ12057"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 13: Lung - Secretion | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,267 | 2 |
ENSG00000114656 | CFAP92 | Cilia and flagella associated protein 92 (putative) | [
"Q9ULG3"
] | 3 | 128909866-129002690 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA042811",
"HPA048445"
] | [
"FAP92",
"FLJ43738",
"KIAA1257"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 17: Choroid plexus - Cilium | Cluster 32: Non-specific - Cell proliferation | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 56: Ciliated tissues - Cilium organization | Tissue enriched | Detected in many | 5 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 12 | 1 | 0 | 1 | [] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma"
] | 4,268 | 7 |
ENSG00000114670 | NEK11 | NIMA related kinase 11 | [
"Q8NG66"
] | 3 | 131026850-131350465 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA016908"
] | [
"FLJ23495"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 3 | null | null | null | Cluster 3: Choroid plexus - Cilium | Cluster 10: Ciliated cells - Ion channel activity | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 4,269 | 2 |
ENSG00000114686 | MRPL3 | Mitochondrial ribosomal protein L3 | [
"P09001"
] | 3 | 131462212-131502983 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043665",
"HPA060132"
] | [
"MRL3",
"RPML3"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [
"Disease variant",
"Primary mitochondrial disease"
] | [] | [] | [] | [] | null | Approved | null | 76 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 17: Non-specific - RNA processing | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 4 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,270 | 5 |
ENSG00000114698 | PLSCR4 | Phospholipid scramblase 4 | [
"Q9NRQ2"
] | 3 | 146192335-146251179 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002276"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [] | [] | [] | Approved | Uncertain | null | 49 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,271 | 4 |
ENSG00000114735 | HEMK1 | HemK methyltransferase family member 1 | [
"Q9Y5R4"
] | 3 | 50569152-50596168 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA034701",
"HPA034702"
] | [
"MTQ1"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Methyltransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 18 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 3: Choroid plexus - Cilium | Cluster 8: Non-specific - Basic cellular processes | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 4,272 | 7 |
ENSG00000114737 | CISH | Cytokine inducible SH2 containing protein | [
"Q9NSE2"
] | 3 | 50606489-50611774 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB034039",
"HPA040812"
] | [
"CIS",
"CIS-1",
"G18",
"SOCS"
] | [
"Predicted intracellular proteins"
] | [
"Growth regulation",
"Ubl conjugation pathway"
] | [
"Signal transduction inhibitor"
] | [] | [
"Microtubules"
] | [
"Cytokinetic bridge"
] | [] | [] | Approved | Approved | null | 14 | Yes | No | Cluster 11: T-cells - Unknown function | Cluster 8: Immune cells - Immune response | Cluster 21: Lymphoma - Adaptive immune response | Cluster 81: Alveolar cells - Lung function | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 6 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | 4,273 | 6 |
ENSG00000114738 | MAPKAPK3 | MAPK activated protein kinase 3 | [
"Q16644"
] | 3 | 50611520-50649291 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA058275"
] | [
"3pK",
"MAPKAP3",
"MK-3",
"MK3"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 19 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 44: Non-specific - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 41: Striated muscle - Muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 4,274 | 9 |
ENSG00000114739 | ACVR2B | Activin A receptor type 2B | [
"Q13705"
] | 3 | 38453890-38493142 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025115",
"HPA040384"
] | [
"ActR-IIB"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins"
] | [] | [
"Kinase",
"Receptor",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Cancer-related genes",
"Disease variant",
"Heterotaxy"
] | [] | [] | [] | [] | null | Approved | null | 14 | null | No | null | Cluster 25: Non-specific - Transcription | Cluster 34: Testis cancer - Unknown function | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,275 | 5 |
ENSG00000114742 | WDR48 | WD repeat domain 48 | [
"Q8TAF3"
] | 3 | 39052013-39096671 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038421",
"HPA058015"
] | [
"Bun62",
"KIAA1449",
"P80",
"SPG60"
] | [
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Host-virus interaction",
"Ubl conjugation pathway"
] | [
"DNA-binding"
] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | Approved | null | 38 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 14: Neurons - Synaptic function | Cluster 8: Non-specific - Basic cellular processes | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 4,276 | 7 |
ENSG00000114745 | GORASP1 | Golgi reassembly stacking protein 1 | [
"Q9BQQ3"
] | 3 | 39095222-39108369 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA056283"
] | [
"FLJ23443",
"GOLPH5",
"GRASP65",
"P65"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | Supported | null | 19 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 27: Non-specific - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,278 | 3 |
ENSG00000114757 | PEX5L | Peroxisomal biogenesis factor 5 like | [
"Q8IYB4"
] | 3 | 179794958-180037053 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA058026"
] | [
"PEX5R",
"PXR2",
"TRIP8b"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | Cluster 28: Oligodendrocytes - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,279 | 9 |
ENSG00000114767 | RRP9 | Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein | [
"O43818"
] | 3 | 51933429-51941904 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038798"
] | [
"RNU3IP2",
"U3-55K"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"rRNA processing"
] | [
"Ribonucleoprotein",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Uncertain | Uncertain | null | 42 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 38: Sub-cortical - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 17: Non-specific - RNA processing | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Prostate Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Prostate Adenocarcinoma"
] | 4,280 | 6 |
ENSG00000114770 | ABCC5 | ATP binding cassette subfamily C member 5 | [
"O15440"
] | 3 | 183919934-184017939 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044067",
"HPA052295"
] | [
"EST277145",
"MOAT-C",
"MRP5",
"SMRP"
] | [
"Cancer-related genes",
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [
"Translocase"
] | [
"Cancer-related genes"
] | [
"Plasma membrane",
"Cell Junctions"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 5 | null | null | Cluster 41: Basophils - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Lung Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Prostate Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma",
"Prostate Adenocarcinoma"
] | 4,281 | 2 |
ENSG00000114771 | AADAC | Arylacetamide deacetylase | [
"P22760"
] | 3 | 151814073-151828488 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002911"
] | [
"CES5A1",
"DAC"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | null | null | Cluster 7: Liver cancer - Metabolism | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 76: Non-specific - Metabolism | Group enriched | Detected in many | 9 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 20 | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 4,282 | 2 |
ENSG00000114779 | ABHD14B | Abhydrolase domain containing 14B | [
"Q96IU4"
] | 3 | 51968510-51983409 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036444",
"HPA036642"
] | [
"CIB",
"MGC15429"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Acyltransferase",
"Transferase"
] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [
"Cytosol"
] | [] | [] | Supported | Supported | null | 2 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 42: Choroid plexus - Mitochondria | Cluster 8: Non-specific - Basic cellular processes | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,283 | 5 |
ENSG00000114786 | ABHD14A-ACY1 | ABHD14A-ACY1 readthrough | [] | 3 | 51974706-51989183 | Evidence at protein level | Evidence at protein level | null | null | [
"HPA036174",
"HPA036175",
"HPA038153",
"HPA071834"
] | [] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | Approved | null | null | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 35: Non-specific - DNA binding | Cluster 12: Bone cancer - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | null | Not detected | Not detected | null | Not detected | Not detected | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 4,285 | 7 |
ENSG00000114790 | ARHGEF26 | Rho guanine nucleotide exchange factor 26 | [
"Q96DR7"
] | 3 | 154121003-154257827 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017722",
"HPA049195"
] | [
"DKFZP434D146",
"SGEF"
] | [
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Plasma membrane"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Approved | null | 5 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 3: Rhabdoid - Membrane components | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 6 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Lung Squamous Cell Carcinoma"
] | [] | [
"Lung Squamous Cell Carcinoma"
] | 4,286 | 2 |
ENSG00000114796 | KLHL24 | Kelch like family member 24 | [
"Q6TFL4"
] | 3 | 183635610-183684519 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA056337"
] | [
"DRE1",
"FLJ20059"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [
"Cardiomyopathy",
"Disease variant",
"Epidermolysis bullosa"
] | [] | [] | [] | [] | null | Uncertain | null | 5 | null | null | Cluster 32: Basophils - Transcription | Cluster 16: Non-specific - Transcription | Cluster 63: Non-specific - Protein processing | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 41: Striated muscle - Muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,287 | 9 |
ENSG00000114805 | PLCH1 | Phospholipase C eta 1 | [
"Q4KWH8"
] | 3 | 155375580-155745071 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036176",
"HPA057978"
] | [
"DKFZp434C1372",
"KIAA1069",
"MGC117152",
"PLCeta1",
"PLCL3"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Lipid degradation",
"Lipid metabolism"
] | [
"Hydrolase",
"Transducer"
] | [
"Disease variant",
"Holoprosencephaly"
] | [
"Vesicles"
] | [] | [] | [] | Enhanced | Uncertain | null | 18 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 32: Retina & Lymphoid tissues - Signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 4,288 | 7 |
ENSG00000114812 | VIPR1 | Vasoactive intestinal peptide receptor 1 | [
"P32241"
] | 3 | 42489299-42537573 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026777"
] | [
"HVR1",
"RDC1",
"VPAC1",
"VPAC1R"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [] | [] | [] | [] | null | Approved | null | 118 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 53: Neurons - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 4 | 1 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,289 | 7 |
ENSG00000114841 | DNAH1 | Dynein axonemal heavy chain 1 | [
"Q9P2D7"
] | 3 | 52316319-52400492 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036805",
"HPA036806"
] | [
"DNAHC1",
"HDHC7",
"HL-11",
"HL11",
"XLHSRF-1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Motor protein"
] | [
"Ciliopathy",
"Disease variant",
"Kartagener syndrome",
"Primary ciliary dyskinesia"
] | [] | [] | [] | [] | null | Uncertain | null | 1 | null | null | null | Cluster 17: Choroid plexus - Cilium | Cluster 6: Leukemia - Signal transduction | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | 4,290 | 7 |
ENSG00000114850 | SSR3 | Signal sequence receptor subunit 3 | [
"Q9UNL2"
] | 3 | 156539553-156555149 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014906"
] | [
"TRAPG"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 34 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 27: Non-specific - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 8: Non-specific - Secretory pathway | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 7 | 2 | 6 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,291 | 9 |
ENSG00000114853 | ZBTB47 | Zinc finger and BTB domain containing 47 | [
"Q9UFB7"
] | 3 | 42653697-42667580 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA074057"
] | [
"DKFZp434N0615",
"KIAA1190",
"ZNF651"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Enhanced | null | 8 | null | null | null | Cluster 13: Oligodendrocytes - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 4,292 | 8 |
ENSG00000114854 | TNNC1 | Troponin C1, slow skeletal and cardiac type | [
"P63316"
] | 3 | 52451100-52454041 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002450",
"HPA044848",
"HPA056897"
] | [
"TNNC"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Muscle protein"
] | [
"Cardiomyopathy",
"Disease variant",
"FDA approved drug targets"
] | [
"Nucleoplasm",
"Actin filaments",
"Mitochondria"
] | [] | [] | [] | Approved | Enhanced | null | 15 | null | null | null | Cluster 5: Non-specific - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 62: Skeletal muscle - Muscle contraction | Group enriched | Detected in many | 37 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in many | 6 | Immune cell enhanced | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 4,293 | 5 |
ENSG00000114857 | NKTR | Natural killer cell triggering receptor | [
"P30414"
] | 3 | 42600655-42648735 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022120",
"HPA051576"
] | [
"p104"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Isomerase",
"Rotamase"
] | [] | [
"Nucleoplasm",
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 16 | No | No | Cluster 21: Neutrophils - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 56: Non-specific - Sensory perception | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Bladder Urothelial Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 4,294 | 6 |
ENSG00000114859 | CLCN2 | Chloride voltage-gated channel 2 | [
"P51788"
] | 3 | 184346185-184361650 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB009397",
"HPA014545",
"HPA024108"
] | [
"ClC-2",
"CLC2",
"EJM6"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Chloride channel",
"Ion channel",
"Voltage-gated channel"
] | [
"Disease variant",
"Epilepsy",
"FDA approved drug targets"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | null | null | null | null | Cluster 13: Oligodendrocytes - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 21: Testis - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 4,295 | 3 |
ENSG00000114861 | FOXP1 | Forkhead box P1 | [
"Q9H334"
] | 3 | 70954693-71583978 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003876",
"CAB011501"
] | [
"12CC4",
"hFKH1B",
"HSPC215",
"QRF1"
] | [
"Cancer-related genes",
"Disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 32 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 53: Neurons - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 4,296 | 2 |
ENSG00000114867 | EIF4G1 | Eukaryotic translation initiation factor 4 gamma 1 | [
"Q04637"
] | 3 | 184314495-184335358 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB014774",
"HPA028487",
"HPA043866"
] | [
"EIF4F",
"EIF4G",
"p220",
"PARK18"
] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Protein biosynthesis",
"Translation regulation"
] | [
"Initiation factor",
"RNA-binding",
"Translational shunt"
] | [
"Cancer-related genes",
"Disease variant",
"Neurodegeneration",
"Parkinson disease",
"Parkinsonism"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 108 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,297 | 4 |
ENSG00000114902 | SPCS1 | Signal peptidase complex subunit 1 | [
"Q9Y6A9"
] | 3 | 52704955-52711148 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA046091",
"HPA055273"
] | [
"HSPC033",
"SPC1",
"SPC12",
"YJR010C-A"
] | [
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Golgi apparatus",
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 13 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 21: Non-specific - Metabolism | Cluster 8: Non-specific - Basic cellular processes | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 8: Pancreas - Proteolysis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme"
] | [
"Bladder Urothelial Carcinoma",
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 4,298 | 8 |
ENSG00000114904 | NEK4 | NIMA related kinase 4 | [
"P51957"
] | 3 | 52708444-52770946 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015750",
"HPA058543"
] | [
"NRK2",
"pp12301",
"STK2"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 30 | null | null | Cluster 41: Basophils - Unknown function | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 8: Non-specific - Basic cellular processes | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 61: Non-specific - Transcription | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,299 | 6 |
ENSG00000114923 | SLC4A3 | Solute carrier family 4 member 3 | [
"P48751"
] | 2 | 219627394-219641980 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA063498"
] | [
"AE3",
"SLC2C"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Anion exchange",
"Antiport",
"Ion transport",
"Transport"
] | [] | [
"Disease variant",
"Short QT syndrome"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | null | 1 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 69: Skin cancer - ECM organization | Cluster 109: Neurons - Neuronal signaling | Cluster 35: Non-specific - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Group enriched | Detected in some | 34 | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 4,300 | 6 |
ENSG00000114933 | INO80D | INO80 complex subunit D | [
"Q53TQ3"
] | 2 | 205993721-206086303 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043976"
] | [
"FLJ20309"
] | [
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA recombination",
"DNA repair",
"Transcription",
"Transcription regulation"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 12 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 16: Non-specific - Transcription | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 102: Non-specific - Mixed function | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 4,301 | 6 |
ENSG00000114942 | EEF1B2 | Eukaryotic translation elongation factor 1 beta 2 | [
"P24534"
] | 2 | 206159585-206162928 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB012477",
"HPA035029"
] | [] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Elongation factor"
] | [] | [
"Nucleoli fibrillar center",
"Cytosol"
] | [] | [] | [] | Approved | Supported | null | 27 | null | null | Cluster 24: Non-specific - Transcription | Cluster 36: Choroid plexus - Mixed function | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,302 | 2 |
ENSG00000114948 | ADAM23 | ADAM metallopeptidase domain 23 | [
"O75077"
] | 2 | 206443532-206621127 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA012130",
"CAB033276"
] | [
"MDC3"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [
"Secreted in brain"
] | [
"Cell adhesion"
] | Approved | Approved | null | 1 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 7: Liver cancer - Metabolism | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 69: Parathyroid gland - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 16 | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 4,303 | 2 |
ENSG00000114956 | DGUOK | Deoxyguanosine kinase | [
"Q16854"
] | 2 | 73926826-73958961 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034766",
"HPA057246"
] | [
"dGK"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Transferase"
] | [
"Disease variant",
"Neuropathy",
"Primary mitochondrial disease",
"Progressive external ophthalmoplegia"
] | [] | [] | [] | [] | null | Approved | null | 3 | null | null | Cluster 41: Basophils - Unknown function | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 97: Non-specific - Cellular respiration | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,304 | 4 |
ENSG00000114978 | MOB1A | MOB kinase activator 1A | [
"Q9H8S9"
] | 2 | 74152528-74178898 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047088",
"HPA071690"
] | [
"C2orf6",
"FLJ10788",
"FLJ11595",
"Mats1",
"MOB1",
"Mob4B",
"MOBK1B",
"MOBKL1B"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Approved | Supported | null | 60 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 39: Astrocytes - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 47: Platelets - Hemostasis | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,305 | 5 |
ENSG00000114982 | KANSL3 | KAT8 regulatory NSL complex subunit 3 | [
"Q9P2N6"
] | 2 | 96593170-96642787 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035017",
"HPA035018"
] | [
"FLJ10081",
"KIAA1310",
"NSL3",
"Rcd1"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Chromatin regulator"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Supported | Approved | null | 14 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 21: Non-specific - Metabolism | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,306 | 9 |
ENSG00000114988 | LMAN2L | Lectin, mannose binding 2 like | [
"Q9H0V9"
] | 2 | 96705929-96740064 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026600"
] | [
"DKFZp564L2423",
"VIPL"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [] | [
"Disease variant",
"Intellectual disability"
] | [] | [] | [] | [] | null | Approved | null | 11 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 27: Breast cancer - Unknown function | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | 4,307 | 9 |
ENSG00000114993 | RTKN | Rhotekin | [
"Q9BST9"
] | 2 | 74425835-74442422 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030259"
] | [
"B5"
] | [
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 14 | No | No | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 65: Non-specific - Cell growth & division | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 4 | 1 | 0 | 1 | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | 4,308 | 8 |
ENSG00000114999 | TTL | Tubulin tyrosine ligase | [
"Q8NG68"
] | 2 | 112482156-112541739 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA066819"
] | [
"MGC46235"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Ligase"
] | [] | [
"Vesicles"
] | [
"Nucleoplasm"
] | [] | [] | Approved | null | null | 3 | null | null | null | Cluster 34: Non-specific - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in some | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,309 | 7 |
ENSG00000115008 | IL1A | Interleukin 1 alpha | [
"P01583"
] | 2 | 112773925-112784493 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA075911",
"CAB080496"
] | [
"IL-1A",
"IL1",
"IL1-ALPHA",
"IL1F1"
] | [
"Cancer-related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins",
"Transporters"
] | [
"Inflammatory response"
] | [
"Cytokine",
"Mitogen",
"Pyrogen"
] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [] | [
"Secreted to blood"
] | [
"Interleukin"
] | Supported | null | null | 10 | null | null | null | Cluster 20: Macrophages & Microglia - Immune response | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 10 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Lung Squamous Cell Carcinoma",
"Stomach Adenocarcinoma"
] | [
"Lung Squamous Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 4,310 | 8 |
ENSG00000115009 | CCL20 | C-C motif chemokine ligand 20 | [
"P78556"
] | 2 | 227805739-227817564 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CKb4",
"exodus-1",
"LARC",
"MIP-3a",
"SCYA20",
"ST38"
] | [
"Predicted secreted proteins"
] | [
"Chemotaxis",
"Inflammatory response"
] | [
"Antibiotic",
"Antimicrobial",
"Cytokine"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Chemokine"
] | null | null | null | 4 | null | null | Cluster 1: T-cells - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 34: Lymphoid tissue - Adaptive immune response | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 4 | 0 | 4 | [
"Colon Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,311 | 3 |
ENSG00000115020 | PIKFYVE | Phosphoinositide kinase, FYVE-type zinc finger containing | [
"Q9Y2I7"
] | 2 | 208266255-208358746 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042604"
] | [
"FAB1",
"KIAA0981",
"MGC40423",
"p235",
"PIP5K",
"PIP5K3",
"ZFYVE29"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Lipid metabolism"
] | [
"Kinase",
"Transferase"
] | [
"Corneal dystrophy",
"Disease variant"
] | [] | [] | [] | [] | null | Uncertain | null | 12 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 31: Non-specific - Transcription | Cluster 59: Leukemia - T-cell receptor | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 4,312 | 2 |
ENSG00000115041 | KCNIP3 | Potassium voltage-gated channel interacting protein 3 | [
"Q9Y2W7"
] | 2 | 95297327-95386077 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA066717",
"HPA069797"
] | [
"CSEN",
"DREAM",
"KCHIP3"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [
"Apoptosis",
"Ion transport",
"Potassium transport",
"Transcription",
"Transcription regulation",
"Transport"
] | [
"Ion channel",
"Potassium channel",
"Repressor",
"Voltage-gated channel"
] | [] | [
"Vesicles"
] | [] | [
"Intracellular and membrane"
] | [
"Transport"
] | Approved | Enhanced | null | 20 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 4,313 | 1 |
ENSG00000115042 | FAHD2A | Fumarylacetoacetate hydrolase domain containing 2A | [
"Q96GK7"
] | 2 | 95402708-95416616 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042145",
"HPA044987",
"CAB045971",
"CAB045972"
] | [
"CGI-105"
] | [
"Predicted intracellular proteins"
] | [] | [
"Isomerase"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 9 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 53: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 3 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme"
] | 4,314 | 3 |
ENSG00000115053 | NCL | Nucleolin | [
"P19338"
] | 2 | 231453531-231483641 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004210",
"HPA023981",
"HPA071110"
] | [
"C23",
"Nsr1"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"DNA-binding",
"RNA-binding"
] | [] | [
"Nucleoplasm",
"Nucleoli",
"Nucleoli rim"
] | [
"Mitotic chromosome"
] | [] | [] | Enhanced | Supported | null | 300 | Yes | No | Cluster 30: Non-specific - DNA binding | Cluster 6: Non-specific - Immune response | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 4,315 | 2 |
ENSG00000115073 | ACTR1B | Actin related protein 1B | [
"P42025"
] | 2 | 97655939-97664044 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047443"
] | [
"Arp1B",
"CTRN2"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Microtubules"
] | [
"Cytokinetic bridge",
"Primary cilium",
"Cytosol"
] | [] | [] | Uncertain | null | null | 50 | Yes | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 14: Neurons - Synaptic function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 97: Non-specific - Cellular respiration | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,316 | 9 |
ENSG00000115084 | SLC35F5 | Solute carrier family 35 member F5 | [
"Q8WV83"
] | 2 | 113705011-113756693 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA034828",
"HPA049229"
] | [
"FLJ22004"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [] | [] | [] | Uncertain | Uncertain | null | null | null | null | Cluster 14: Non-specific - Unknown function | Cluster 50: Non-specific - Nucleic acid binding | Cluster 15: Kidney cancer - Membrane components | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in some | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,317 | 3 |
ENSG00000115085 | ZAP70 | Zeta chain of T cell receptor associated protein kinase 70 | [
"P43403"
] | 2 | 97713576-97739862 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002625",
"HPA003134"
] | [
"SRK",
"STD",
"ZAP-70"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Adaptive immunity",
"Immunity"
] | [
"Kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Disease variant",
"SCID"
] | [] | [] | [] | [] | null | Enhanced | null | 31 | null | null | Cluster 1: T-cells - Unknown function | Cluster 38: Sub-cortical - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 4 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in many | 41 | 3 | 0 | 3 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,318 | 8 |
ENSG00000115091 | ACTR3 | Actin related protein 3 | [
"P61158"
] | 2 | 113890063-113962596 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005085",
"HPA047016",
"HPA051683"
] | [
"ARP3"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [
"Actin-binding"
] | [] | [] | [] | [] | [] | null | Approved | null | 75 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 21: Non-specific - Metabolism | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 34: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 4,319 | 8 |
ENSG00000115107 | STEAP3 | STEAP3 metalloreductase | [
"Q658P3"
] | 2 | 119223831-119265652 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA050510"
] | [
"dudlin-2",
"STMP3",
"TSAP6"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Apoptosis",
"Cell cycle",
"Ion transport",
"Iron transport",
"Transport"
] | [
"Oxidoreductase"
] | [] | [
"Cytosol"
] | [
"Nucleoli"
] | [] | [] | Approved | Approved | null | 16 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 49: Hindbrain - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 53: Liver - Plasma proteins | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 5 | 4 | 4 | 2 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,320 | 7 |
ENSG00000115109 | EPB41L5 | Erythrocyte membrane protein band 4.1 like 5 | [
"Q9HCM4"
] | 2 | 120013077-120179119 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037563",
"HPA037564"
] | [
"BE37",
"FLJ12957",
"KIAA1548",
"LULU",
"LULU1",
"YMO1",
"YRT"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [] | [] | [] | Enhanced | Uncertain | null | 22 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 2: Neurons - Nucleosome | Cluster 15: Kidney cancer - Membrane components | Cluster 57: Podocytes - Glomerular filtration | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 4,321 | 6 |
ENSG00000115112 | TFCP2L1 | Transcription factor CP2 like 1 | [
"Q9NZI6"
] | 2 | 121216587-121285202 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029708"
] | [
"CRTR1",
"LBP-9"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoli fibrillar center"
] | [
"Mitochondria"
] | [] | [] | Approved | Uncertain | null | 1 | Yes | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 10: Ciliated cells - Ion channel activity | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 4,322 | 8 |
ENSG00000115128 | SF3B6 | Splicing factor 3b subunit 6 | [
"Q9Y3B4"
] | 2 | 24067586-24076373 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034829",
"HPA034830"
] | [
"CGI-110",
"Ht006",
"P14",
"SAP14a",
"SF3B14a"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 101 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 55: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,323 | 9 |
ENSG00000115129 | TP53I3 | Tumor protein p53 inducible protein 3 | [
"Q53FA7"
] | 2 | 24077433-24085861 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017479",
"HPA022012",
"HPA028742"
] | [
"PIG3"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | Enhanced | null | 3 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 38: Sub-cortical - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 4,324 | 6 |
ENSG00000115137 | DNAJC27 | DnaJ heat shock protein family (Hsp40) member C27 | [
"Q9NZQ0"
] | 2 | 24943636-24972094 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036815",
"HPA036816"
] | [
"RabJS",
"RBJ"
] | [
"Predicted intracellular proteins"
] | [] | [] | [
"Oncogene"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 6 | null | null | null | Cluster 45: Non-specific - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 103: Non-specific - Basic cellular processes | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in single | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,325 | 1 |
ENSG00000115138 | POMC | Proopiomelanocortin | [
"P01189"
] | 2 | 25160853-25168903 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002762",
"HPA046135",
"HPA063644",
"CAB079881"
] | [
"ACTH",
"CLIP",
"LPH",
"MSH",
"NPP",
"POC"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted secreted proteins"
] | [] | [
"Endorphin",
"Hormone"
] | [
"Cancer-related genes",
"Obesity"
] | [] | [] | [
"Secreted to blood"
] | [
"Hormone"
] | null | Enhanced | null | 14 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 10: Ciliated cells - Ion channel activity | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 20: Pituitary gland - Hormone signaling | Tissue enriched | Detected in many | 636 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in many | 4 | Cell type enriched | Detected in many | 151 | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 4,326 | 4 |
ENSG00000115159 | GPD2 | Glycerol-3-phosphate dehydrogenase 2 | [
"P43304"
] | 2 | 156435290-156613735 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008012",
"HPA045506"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 4 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 29: Forebrain - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Group enriched | Detected in many | 4 | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 4,329 | 8 |
ENSG00000115163 | CENPA | Centromere protein A | [
"P49450"
] | 2 | 26764289-26801067 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB008371",
"HPA073086"
] | [
"CenH3",
"CENP-A"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Host-virus interaction",
"Mitosis"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 50 | null | Yes | null | null | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 2 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,330 | 6 |
ENSG00000115165 | CYTIP | Cytohesin 1 interacting protein | [
"O60759"
] | 2 | 157414619-157488961 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007191"
] | [
"B3-1",
"CASP",
"CYBR",
"CYTHIP",
"HE",
"PSCDBP"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 9 | No | null | Cluster 35: Neutrophils - Protein binding | Cluster 12: Non-specific - Vasculature | Cluster 71: Lymphoma - Inflammatory response | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 7 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 4,331 | 8 |
ENSG00000115183 | TANC1 | Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | [
"Q9C0D5"
] | 2 | 158968640-159232659 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036750"
] | [
"KIAA1728",
"ROLSB"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 15 | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 47: Leukemia - Hemostasis | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 58: Skin - Keratinization | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 4 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,333 | 8 |
ENSG00000115194 | SLC30A3 | Solute carrier family 30 member 3 | [
"Q99726"
] | 2 | 27253684-27275817 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA060505",
"HPA067637",
"CAB079044"
] | [
"ZNT3"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Ion transport",
"Transport",
"Zinc transport"
] | [] | [] | [
"Vesicles"
] | [
"Nucleoplasm",
"Nucleoli",
"Cytosol"
] | [] | [] | Approved | Enhanced | Approved | 32 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 10: Epididymal principal cells - Sperm maturation microenvironment | Cluster 22: Epididymis - Mixed function | Group enriched | Detected in some | 6 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,334 | 8 |
ENSG00000115204 | MPV17 | Mitochondrial inner membrane protein MPV17 | [
"P39210"
] | 2 | 27309492-27325680 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"SYM1"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy",
"Primary mitochondrial disease"
] | [] | [] | [] | [] | null | null | null | 1 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 27: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 97: Non-specific - Cellular respiration | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Thyroid Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | 4,335 | 6 |
ENSG00000115207 | GTF3C2 | General transcription factor IIIC subunit 2 | [
"Q8WUA4"
] | 2 | 27325849-27356999 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008274",
"HPA035836"
] | [
"KIAA0011",
"TFIIIC110"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 22 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 48: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Lung Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 4,336 | 3 |
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