ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000115896 | PLCL1 | Phospholipase C like 1 (inactive) | [
"Q15111"
] | 2 | 197804593-198572581 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031849"
] | [
"PLC-L",
"PLCE",
"PLCL",
"PPP1R127",
"PRIP"
] | [
"Predicted intracellular proteins"
] | [] | [
"Transducer"
] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 4,455 | 6 |
ENSG00000115902 | SLC1A4 | Solute carrier family 1 member 4 | [
"P43007"
] | 2 | 64988477-65023865 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034963",
"HPA034964"
] | [
"ASCT-1",
"ASCT1",
"SATT"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Symport",
"Transport"
] | [] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Centrosome"
] | [] | [] | [] | Enhanced | Enhanced | null | 8 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 1: Neurons - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 4,456 | 5 |
ENSG00000115904 | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1 | [
"Q07889"
] | 2 | 38962206-39124345 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB005396"
] | [
"GF1",
"GINGF",
"HGF"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 54 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 31: Non-specific - Transcription | Cluster 49: HMC-1 - Innate immune response | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 4,457 | 9 |
ENSG00000115919 | KYNU | Kynureninase | [
"Q16719"
] | 2 | 142877657-143055833 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031686"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Pyridine nucleotide biosynthesis"
] | [
"Hydrolase"
] | [
"Disease variant"
] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 2 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 48: Non-specific - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 17 | 4 | 0 | 4 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,458 | 7 |
ENSG00000115935 | WIPF1 | WAS/WASL interacting protein family member 1 | [
"O43516"
] | 2 | 174559572-174682916 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003739",
"CAB009737",
"HPA070706"
] | [
"WASPIP",
"WIP"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Enhanced | null | 26 | No | No | Cluster 35: Neutrophils - Protein binding | Cluster 30: White matter - Myelination | Cluster 46: Lymphoma - Humoral immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 4,459 | 3 |
ENSG00000115942 | ORC2 | Origin recognition complex subunit 2 | [
"Q13416"
] | 2 | 200908977-200963680 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB003693",
"HPA073881"
] | [
"ORC2L"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"DNA replication"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 47 | null | null | Cluster 24: Non-specific - Transcription | Cluster 31: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe"
] | 4,460 | 4 |
ENSG00000115944 | COX7A2L | Cytochrome c oxidase subunit 7A2 like | [
"O14548"
] | 2 | 42333546-42425088 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA059124",
"CAB073545"
] | [
"COX7AR",
"COX7RP",
"EB1",
"SCAF1",
"SCAFI",
"SIG81"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [
"Nucleoli"
] | [] | [] | Enhanced | null | null | 7 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 14: Neurons - Synaptic function | Cluster 25: Non-specific - Ribosome | Cluster 97: Non-specific - Cellular respiration | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,461 | 6 |
ENSG00000115946 | PNO1 | Partner of NOB1 homolog | [
"Q9NRX1"
] | 2 | 68157888-68176238 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA056928"
] | [
"KHRBP1",
"RRP20"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"RNA-binding"
] | [] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Supported | null | null | 40 | null | Yes | Cluster 33: Non-specific - ATP binding | Cluster 29: Forebrain - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,462 | 7 |
ENSG00000115947 | ORC4 | Origin recognition complex subunit 4 | [
"O43929"
] | 2 | 147930396-148021604 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB015124",
"HPA064562"
] | [
"HsORC4",
"ORC4L",
"Orc4p"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"DNA replication"
] | [
"DNA-binding"
] | [
"Disease variant",
"Dwarfism"
] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | [] | Supported | Approved | null | 39 | null | null | Cluster 24: Non-specific - Transcription | Cluster 2: Neurons - Nucleosome | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 4,463 | 4 |
ENSG00000115956 | PLEK | Pleckstrin | [
"P08567"
] | 2 | 68365282-68397453 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031838",
"HPA057341"
] | [
"P47",
"PLEK1"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli"
] | [] | [] | [] | Approved | Enhanced | null | 4 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 12: Non-specific - Vasculature | Cluster 55: Lymphoma - Immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in many | 5 | Group enriched | Detected in some | 43 | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 5 | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 4,464 | 8 |
ENSG00000115963 | RND3 | Rho family GTPase 3 | [
"P61587"
] | 2 | 150468195-150539011 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA060504"
] | [
"ARHE",
"Rho8",
"RhoE"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 15 | null | null | null | Cluster 29: Forebrain - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,465 | 8 |
ENSG00000115966 | ATF2 | Activating transcription factor 2 | [
"P15336"
] | 2 | 175072250-175168382 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB003769",
"HPA022134"
] | [
"CRE-BP1",
"CREB2",
"HB16",
"TREB7"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"DNA damage",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | Supported | 92 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 34: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,466 | 7 |
ENSG00000115970 | THADA | THADA armadillo repeat containing | [
"Q6YHU6"
] | 2 | 43230851-43596038 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035191",
"HPA035192"
] | [
"ARMC13",
"FLJ21877",
"GITA",
"KIAA1767",
"Trm732"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 24 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 3: Choroid plexus - Cilium | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 7: Non-specific - Transcription | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,467 | 8 |
ENSG00000115977 | AAK1 | AP2 associated kinase 1 | [
"Q2M2I8"
] | 2 | 69457997-69674349 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017931",
"HPA020289"
] | [
"DKFZp686K16132",
"KIAA1048"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Endocytosis"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Plasma membrane"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 28 | No | No | Cluster 11: T-cells - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 59: Leukemia - T-cell receptor | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 69: Parathyroid gland - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [] | [
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,468 | 6 |
ENSG00000115993 | TRAK2 | Trafficking kinesin protein 2 | [
"O60296"
] | 2 | 201377207-201451500 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015827",
"HPA062163"
] | [
"ALS2CR3",
"CALS-C",
"GRIF-1",
"KIAA0549",
"MILT2",
"OIP98"
] | [
"Predicted intracellular proteins"
] | [
"Transport"
] | [] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Vesicles"
] | [] | [] | Approved | Uncertain | null | 25 | null | null | Cluster 16: Non-specific - Cell proliferation | Cluster 30: White matter - Myelination | Cluster 47: Leukemia - Hemostasis | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,469 | 6 |
ENSG00000116001 | TIA1 | TIA1 cytotoxic granule associated RNA binding protein | [
"P31483"
] | 2 | 70209444-70248660 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA056961"
] | [
"TIA-1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"mRNA processing",
"mRNA splicing"
] | [
"RNA-binding"
] | [
"Amyotrophic lateral sclerosis",
"Disease variant",
"Neurodegeneration"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 10 | null | null | Cluster 18: Non-specific - Translation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 17: Non-specific - RNA processing | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | 4,471 | 6 |
ENSG00000116016 | EPAS1 | Endothelial PAS domain protein 1 | [
"Q99814"
] | 2 | 46293667-46386697 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031200",
"HPA069697"
] | [
"bHLHe73",
"HIF2A",
"HLF",
"MOP2",
"PASD2"
] | [
"Cancer-related genes",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Angiogenesis",
"Differentiation",
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes",
"Congenital erythrocytosis",
"Disease variant",
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [
"Actin filaments",
"Cytokinetic bridge",
"Cytosol"
] | [] | [] | Supported | null | null | 43 | Yes | null | Cluster 46: Basophils - Proteolysis | Cluster 42: Choroid plexus - Mitochondria | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 18 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 4,474 | 5 |
ENSG00000116017 | ARID3A | AT-rich interaction domain 3A | [
"Q99856"
] | 19 | 925781-975939 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004793",
"HPA076330"
] | [
"BRIGHT",
"DRIL1"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 22 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 48: Non-specific - Mixed function | Cluster 34: Testis cancer - Unknown function | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 3 | [
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,475 | 6 |
ENSG00000116030 | SUMO1 | Small ubiquitin like modifier 1 | [
"P63165"
] | 2 | 202206182-202238599 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004269",
"HPA056956"
] | [
"GMP1",
"OFC10",
"PIC1",
"SMT3C",
"SMT3H3",
"SUMO-1",
"UBL1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Ubl conjugation pathway"
] | [] | [] | [
"Nuclear membrane",
"Nuclear bodies"
] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | Supported | Supported | null | 155 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 31: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 97: Non-specific - Cellular respiration | Cluster 16: Liver & Kidney - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,476 | 7 |
ENSG00000116031 | CD207 | CD207 molecule | [
"Q9UJ71"
] | 2 | 70830211-70835816 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002222",
"HPA011216"
] | [
"CLEC4K",
"Langerin"
] | [
"CD markers",
"Disease related genes",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Uncertain | Enhanced | null | 8 | No | null | null | null | Cluster 12: Bone cancer - Neuronal signaling | Cluster 82: Dendritic cells - Antigen presentation | Cluster 37: Skin - Keratinization | Tissue enriched | Detected in many | 5 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 4 | Immune cell enriched | Detected in single | 12 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,477 | 8 |
ENSG00000116032 | GRIN3B | Glutamate ionotropic receptor NMDA type subunit 3B | [
"O60391"
] | 19 | 1000419-1009732 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [] | [
"GluN3B"
] | [
"FDA approved drug targets",
"Predicted membrane proteins"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | null | null | 8 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,478 | 3 |
ENSG00000116035 | VAX2 | Ventral anterior homeobox 2 | [
"Q9UIW0"
] | 2 | 70900576-70965373 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA009708"
] | [
"DRES93"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation",
"Wnt signaling pathway"
] | [
"Developmental protein",
"DNA-binding"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | null | null | 4 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 5: Rhabdoid - Unknown function | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in some | 8 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,479 | 3 |
ENSG00000116039 | ATP6V1B1 | ATPase H+ transporting V1 subunit B1 | [
"P15313"
] | 2 | 70935900-70965431 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009523",
"HPA031847"
] | [
"ATP6B1",
"RTA1B",
"VATB",
"Vma2",
"VPP3"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Hydrogen ion transport",
"Ion transport",
"Transport"
] | [] | [
"Deafness",
"Disease variant"
] | [
"Nucleoplasm",
"Nuclear membrane"
] | [] | [] | [] | Approved | Enhanced | null | 43 | No | null | null | Cluster 37: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 72: Kidney - Transmembrane transport | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 15 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,480 | 6 |
ENSG00000116044 | NFE2L2 | NFE2 like bZIP transcription factor 2 | [
"Q16236"
] | 2 | 177218667-177392756 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002990",
"CAB020317",
"HPA043438"
] | [
"NRF-2",
"NRF2"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [
"Golgi apparatus",
"Centrosome",
"Basal body",
"Cytosol"
] | [] | [] | Approved | Supported | null | 153 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,481 | 4 |
ENSG00000116096 | SPR | Sepiapterin reductase | [
"P35270"
] | 2 | 72887382-72892158 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039505"
] | [
"SDR38C1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [
"Disease variant",
"Dystonia"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 1 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 44: Non-specific - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 7 | 0 | 0 | 0 | [] | [] | [] | 4,484 | 1 |
ENSG00000116106 | EPHA4 | EPH receptor A4 | [
"P54764"
] | 2 | 221418027-221574202 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB028368"
] | [
"Hek8",
"TYRO1"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Neurogenesis"
] | [
"Developmental protein",
"Kinase",
"Receptor",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Enhanced | null | 30 | null | null | Cluster 24: Non-specific - Transcription | Cluster 23: Choroid plexus - Mixed function | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 61: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 9 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,485 | 2 |
ENSG00000116117 | PARD3B | Par-3 family cell polarity regulator beta | [
"Q8TEW8"
] | 2 | 204545475-205620162 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035283"
] | [
"ALS2CR19",
"PAR3beta",
"Par3L"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division"
] | [] | [] | [
"Cell Junctions"
] | [] | [] | [] | Supported | Approved | null | 10 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 57: Podocytes - Glomerular filtration | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,486 | 2 |
ENSG00000116120 | FARSB | Phenylalanyl-tRNA synthetase subunit beta | [
"Q9NSD9"
] | 2 | 222566899-222656092 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036677",
"HPA036678",
"HPA061398"
] | [
"FARSLB",
"FRSB",
"PheHB"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Aminoacyl-tRNA synthetase",
"Ligase"
] | [
"Disease variant",
"Intellectual disability",
"Neurodegeneration"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 13 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 14: Neurons - Synaptic function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 17: Non-specific - RNA processing | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 4,487 | 6 |
ENSG00000116127 | ALMS1 | ALMS1 centrosome and basal body associated protein | [
"Q8TCU4"
] | 2 | 73385758-73625166 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035276",
"HPA043200"
] | [
"KIAA0328"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Ciliopathy",
"Cone-rod dystrophy",
"Deafness",
"Diabetes mellitus",
"Obesity"
] | [
"Centrosome",
"Basal body",
"Cytosol",
"Flagellar centriole"
] | [
"Nucleoplasm",
"Microtubules",
"Mid piece",
"End piece"
] | [] | [] | Supported | Enhanced | null | 17 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 54: Immune cells - T cell receptor | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 7: Non-specific - Transcription | Cluster 21: Testis - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,488 | 9 |
ENSG00000116128 | BCL9 | BCL9 transcription coactivator | [
"O00512"
] | 1 | 147541501-147626216 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA020274"
] | [] | [
"Cancer-related genes",
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Wnt signaling pathway"
] | [] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 16 | No | No | Cluster 43: Non-specific - Transcription & Translation | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 45: Non-specific - Nuclear processes | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,489 | 4 |
ENSG00000116132 | PRRX1 | Paired related homeobox 1 | [
"P54821"
] | 1 | 170662728-170739421 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051084",
"HPA063566"
] | [
"PHOX1",
"PMX1"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 2 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,490 | 8 |
ENSG00000116133 | DHCR24 | 24-dehydrocholesterol reductase | [
"Q15392"
] | 1 | 54849627-54887195 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017981",
"CAB037247",
"HPA063005"
] | [
"DCE",
"KIAA0018",
"seladin-1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cholesterol biosynthesis",
"Cholesterol metabolism",
"Lipid biosynthesis",
"Lipid metabolism",
"Steroid biosynthesis",
"Steroid metabolism",
"Sterol biosynthesis",
"Sterol metabolism"
] | [
"Oxidoreductase"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 52 | null | null | Cluster 41: Basophils - Unknown function | Cluster 30: White matter - Myelination | Cluster 15: Kidney cancer - Membrane components | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 4,491 | 2 |
ENSG00000116138 | DNAJC16 | DnaJ heat shock protein family (Hsp40) member C16 | [
"Q9Y2G8"
] | 1 | 15526813-15592379 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA043643"
] | [
"KIAA0962"
] | [
"Predicted membrane proteins"
] | [
"Autophagy"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 41 | null | null | Cluster 24: Non-specific - Transcription | Cluster 31: Non-specific - Transcription | Cluster 37: Non-specific - mRNA processing | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,492 | 4 |
ENSG00000116141 | MARK1 | Microtubule affinity regulating kinase 1 | [
"Q9P0L2"
] | 1 | 220528136-220664461 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA007421",
"HPA008061"
] | [
"MARK",
"PAR-1C"
] | [
"Disease related genes",
"Enzymes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Wnt signaling pathway"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Autism",
"Autism spectrum disorder"
] | [] | [] | [] | [] | null | Uncertain | null | 27 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 46: Brain & retina - Neuronal signaling | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,493 | 3 |
ENSG00000116147 | TNR | Tenascin R | [
"Q92752"
] | 1 | 175315194-175743616 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022343",
"HPA027134",
"HPA027150",
"HPA029859"
] | [] | [
"Disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [
"Disease variant"
] | [] | [] | [
"Secreted in brain"
] | [
"Cell adhesion"
] | null | Enhanced | null | 1 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 73: Brain - Neuronal signaling | Group enriched | Detected in some | 11 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in single | 32 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 4,494 | 5 |
ENSG00000116151 | MORN1 | MORN repeat containing 1 | [
"Q5T089"
] | 1 | 2321253-2391707 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA005858",
"HPA070703"
] | [
"FLJ13941"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Mitochondria"
] | [
"Nucleoli"
] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 33: Non-specific - ATP binding | Cluster 2: Neurons - Nucleosome | Cluster 10: Ciliated cells - Ion channel activity | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 64: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,495 | 1 |
ENSG00000116157 | GPX7 | Glutathione peroxidase 7 | [
"Q96SL4"
] | 1 | 52602371-52609051 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"FLJ14777",
"GPX6",
"NPGPx"
] | [
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Potential drug targets",
"Predicted secreted proteins"
] | [] | [
"Oxidoreductase",
"Peroxidase"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | null | null | 24 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 36: Choroid plexus - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 108: Fibroblasts - ECM organization | Cluster 43: Placenta - Pregnancy hormone signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe"
] | 4,496 | 2 |
ENSG00000116161 | CACYBP | Calcyclin binding protein | [
"Q9HB71"
] | 1 | 174999163-175012027 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA025753",
"HPA057038"
] | [
"S100A6BP",
"SIP"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | Enhanced | null | 46 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 34: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 75: Non-specific - Chaperones and protein folding | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 4,497 | 2 |
ENSG00000116176 | TPSG1 | Tryptase gamma 1 | [
"Q9NRR2"
] | 16 | 1221651-1225268 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA060458"
] | [
"PRSS31",
"TMT"
] | [
"Enzymes",
"Predicted membrane proteins"
] | [] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 2 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 77: Intestine - Digestion | Tissue enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in some | 8 | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Colon Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 4,499 | 1 |
ENSG00000116183 | PAPPA2 | Pappalysin 2 | [
"Q9BXP8"
] | 1 | 176463171-176845601 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018412",
"HPA018430"
] | [
"PAPP-A2",
"PAPPE",
"PLAC3"
] | [
"Disease related genes",
"Enzymes",
"Potential drug targets",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Disease variant",
"Dwarfism"
] | [
"Endoplasmic reticulum",
"Vesicles"
] | [] | [
"Secreted in female reproductive system"
] | [
"Enzyme"
] | Approved | Enhanced | null | null | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 64: Connective tissue cells - ECM organization | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enriched | Detected in some | 9 | Low cancer specificity | Detected in some | null | Group enriched | Detected in some | 6 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 4,500 | 1 |
ENSG00000116191 | RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | [
"Q86X27"
] | 1 | 178725165-178921842 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027143",
"HPA028328"
] | [
"FLJ10244",
"FLJ25604",
"KIAA0351"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [
"Alzheimer disease"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Uncertain | Enhanced | null | 23 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 29: Forebrain - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 32: Retina & Lymphoid tissues - Signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Group enriched | Detected in some | 10 | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 4,501 | 1 |
ENSG00000116194 | ANGPTL1 | Angiopoietin like 1 | [
"O95841"
] | 1 | 178849535-178871077 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA009976"
] | [
"ANG3",
"ANGPT3",
"AngY",
"ARP1"
] | [
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | null | Approved | null | null | null | null | Cluster 34: B-cells - Unknown function | Cluster 29: Forebrain - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 4,502 | 2 |
ENSG00000116198 | CEP104 | Centrosomal protein 104 | [
"O60308"
] | 1 | 3812086-3857396 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA010126"
] | [
"CFAP256",
"GlyBP",
"JBTS25",
"KIAA0562",
"ROC22",
"RP1-286D6.4"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Ciliopathy",
"Disease variant",
"Intellectual disability",
"Joubert syndrome"
] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 6: Non-specific - Immune response | Cluster 37: Non-specific - mRNA processing | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,503 | 9 |
ENSG00000116199 | FAM20B | FAM20B glycosaminoglycan xylosylkinase | [
"O75063"
] | 1 | 179025804-179076567 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007409"
] | [
"GXK1",
"KIAA0475"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Transferase"
] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 21 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 14: Neurons - Synaptic function | Cluster 45: Non-specific - Nuclear processes | Cluster 17: Non-specific - RNA processing | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,504 | 4 |
ENSG00000116205 | TCEANC2 | Transcription elongation factor A N-terminal and central domain containing 2 | [
"Q96MN5"
] | 1 | 54053584-54112519 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046918"
] | [
"C1orf83",
"FLJ32112"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Approved | Uncertain | null | 4 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 6: Non-specific - Immune response | Cluster 37: Non-specific - mRNA processing | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Rectum Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 4,505 | 3 |
ENSG00000116209 | TMEM59 | Transmembrane protein 59 | [
"Q9BXS4"
] | 1 | 54026681-54053504 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA075447"
] | [
"C1orf8",
"HSPC001"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Autophagy"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 46 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 50: Non-specific - Nucleic acid binding | Cluster 37: Non-specific - mRNA processing | Cluster 84: Apical squamous epithelium - Cornification | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 4,506 | 9 |
ENSG00000116212 | LRRC42 | Leucine rich repeat containing 42 | [
"Q9Y546"
] | 1 | 53946085-53968168 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047458",
"HPA050537",
"HPA064581"
] | [
"MGC8974"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 2 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 21: Non-specific - Metabolism | Cluster 37: Non-specific - mRNA processing | Cluster 26: Keratinocytes - Keratinization | Cluster 28: Liver & Adrenal gland - Secretion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,507 | 8 |
ENSG00000116213 | WRAP73 | WD repeat containing, antisense to TP73 | [
"Q9P2S5"
] | 1 | 3630767-3652761 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026893"
] | [
"WDR8"
] | [
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [] | [
"Mid piece",
"Principal piece"
] | [] | [] | [] | Approved | Uncertain | null | 28 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 11: White matter - Signal transduction | Cluster 37: Non-specific - mRNA processing | Cluster 97: Non-specific - Cellular respiration | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 4,508 | 6 |
ENSG00000116218 | NPHS2 | NPHS2 stomatin family member, podocin | [
"Q9NP85"
] | 1 | 179550539-179575952 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB037267",
"HPA049486"
] | [
"PDCN",
"SRN1"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 3 | null | null | null | null | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 57: Podocytes - Glomerular filtration | Cluster 72: Kidney - Transmembrane transport | Tissue enriched | Detected in some | 145 | Not detected | Not detected | null | Cancer enhanced | Detected in single | null | Cell type enriched | Detected in some | 122 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,509 | 8 |
ENSG00000116221 | MRPL37 | Mitochondrial ribosomal protein L37 | [
"Q9BZE1"
] | 1 | 54184041-54225464 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA025767",
"HPA025826",
"HPA025951"
] | [
"MRP-L2",
"RPML2"
] | [
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Supported | null | 105 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 5: Non-specific - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 97: Non-specific - Cellular respiration | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,510 | 1 |
ENSG00000116251 | RPL22 | Ribosomal protein L22 | [
"P35268"
] | 1 | 6185020-6209389 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA068294"
] | [
"EAP",
"L22"
] | [
"Cancer-related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Heparin-binding",
"Ribonucleoprotein",
"Ribosomal protein",
"RNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Uncertain | null | null | 148 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,512 | 4 |
ENSG00000116254 | CHD5 | Chromodomain helicase DNA binding protein 5 | [
"Q8TDI0"
] | 1 | 6101787-6180321 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015809"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Neurogenesis",
"Spermatogenesis",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"DNA-binding",
"Hydrolase"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability",
"Tumor suppressor"
] | [
"Nucleoplasm",
"Nuclear speckles"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 18 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 10: Brain - Synaptic signal transduction | Group enriched | Detected in some | 7 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 4,513 | 1 |
ENSG00000116260 | QSOX1 | Quiescin sulfhydryl oxidase 1 | [
"O00391"
] | 1 | 180154869-180204030 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA056243"
] | [
"QSCN6"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [] | [
"Oxidoreductase"
] | [] | [
"Golgi apparatus"
] | [
"Vesicles"
] | [
"Secreted to extracellular matrix"
] | [
"Enzyme"
] | Supported | null | null | null | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 64: Connective tissue cells - ECM organization | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,514 | 7 |
ENSG00000116266 | STXBP3 | Syntaxin binding protein 3 | [
"O00186"
] | 1 | 108746674-108809523 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA027225"
] | [
"UNC-18C"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 10 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,515 | 5 |
ENSG00000116273 | PHF13 | PHD finger protein 13 | [
"Q86YI8"
] | 1 | 6613731-6624030 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026830"
] | [
"MGC43399"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA condensation",
"Mitosis"
] | [
"Chromatin regulator"
] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | Cluster 33: Non-specific - ATP binding | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 37: Non-specific - mRNA processing | Cluster 26: Keratinocytes - Keratinization | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,516 | 6 |
ENSG00000116285 | ERRFI1 | ERBB receptor feedback inhibitor 1 | [
"Q9UJM3"
] | 1 | 8004404-8026309 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027206",
"HPA076543"
] | [
"GENE-33",
"MIG-6",
"RALT"
] | [
"Predicted intracellular proteins"
] | [] | [] | [
"Tumor suppressor"
] | [
"Cytosol"
] | [] | [] | [] | Enhanced | null | null | 28 | null | null | Cluster 24: Non-specific - Transcription | Cluster 25: Non-specific - Transcription | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 26: Keratinocytes - Keratinization | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 5 | 4 | 0 | 4 | [
"Rectum Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 4,517 | 3 |
ENSG00000116288 | PARK7 | Parkinsonism associated deglycase | [
"Q99497"
] | 1 | 7954291-7985505 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004190",
"CAB005870"
] | [
"DJ-1",
"DJ1",
"GATD2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Autophagy",
"DNA damage",
"DNA repair",
"Fertilization",
"Inflammatory response",
"Stress response"
] | [
"Chaperone",
"Hydrolase",
"Protease",
"RNA-binding"
] | [
"Disease variant",
"Neurodegeneration",
"Parkinson disease",
"Parkinsonism",
"Tumor suppressor"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Flagellar centriole",
"Mid piece"
] | [] | [] | Supported | Supported | null | 78 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 37: Non-specific - mRNA processing | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Papillary Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 4,518 | 1 |
ENSG00000116329 | OPRD1 | Opioid receptor delta 1 | [
"P41143"
] | 1 | 28812170-28871267 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA070831"
] | [] | [
"FDA approved drug targets",
"G-protein coupled receptors",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Approved | null | 13 | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in single | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 4,520 | 3 |
ENSG00000116337 | AMPD2 | Adenosine monophosphate deaminase 2 | [
"Q01433"
] | 1 | 109616104-109632051 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027137",
"HPA045760"
] | [
"SPG63"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Nucleotide metabolism"
] | [
"Hydrolase"
] | [
"Disease variant",
"Hereditary spastic paraplegia",
"Neurodegeneration"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 8 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 32: Cerebral cortex - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 0 | 0 | 0 | [] | [] | [] | 4,521 | 3 |
ENSG00000116350 | SRSF4 | Serine and arginine rich splicing factor 4 | [
"Q08170"
] | 1 | 29147743-29181900 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050975"
] | [
"SFRS4",
"SRP75"
] | [
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Repressor",
"RNA-binding"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Supported | null | 30 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 55: Non-specific - Transcription | Cluster 37: Non-specific - mRNA processing | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Prostate Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Liver Hepatocellular Carcinoma",
"Prostate Adenocarcinoma"
] | 4,522 | 3 |
ENSG00000116353 | MECR | Mitochondrial trans-2-enoyl-CoA reductase | [
"Q9BV79"
] | 1 | 29192657-29230942 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022018",
"HPA022030",
"HPA028740"
] | [
"CGI-63",
"ETR1",
"FASN2B",
"NRBF1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Fatty acid biosynthesis",
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid metabolism"
] | [
"Oxidoreductase"
] | [
"Disease variant",
"Dystonia"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 3 | null | null | Cluster 16: Non-specific - Cell proliferation | Cluster 24: Neurons - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 4,523 | 7 |
ENSG00000116396 | KCNC4 | Potassium voltage-gated channel subfamily C member 4 | [
"Q03721"
] | 1 | 110210314-110283100 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA014740"
] | [
"C1orf30",
"HKSHIIIC",
"Kv3.4"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Ion channel",
"Potassium channel",
"Voltage-gated channel"
] | [] | [
"Nucleoli",
"Cytosol"
] | [] | [] | [] | Approved | null | null | 1 | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 21: Lymphoma - Adaptive immune response | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,524 | 8 |
ENSG00000116406 | EDEM3 | ER degradation enhancing alpha-mannosidase like protein 3 | [
"Q9BZQ6"
] | 1 | 184690237-184754907 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA025754",
"HPA025755",
"HPA027297"
] | [
"C1orf22"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Unfolded protein response"
] | [
"Hydrolase"
] | [
"Congenital disorder of glycosylation"
] | [
"Endoplasmic reticulum"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Approved | Approved | null | 35 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 21: Non-specific - Metabolism | Cluster 51: Myeloma - Immunoglobulins | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 4,525 | 2 |
ENSG00000116455 | WDR77 | WD repeat domain 77 | [
"Q9BQA1"
] | 1 | 111439890-111449256 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026437",
"HPA026448",
"HPA027271"
] | [
"MEP50",
"p44"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Golgi apparatus"
] | [] | [] | Supported | Enhanced | null | 87 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 37: Non-specific - mRNA processing | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 4,526 | 4 |
ENSG00000116459 | ATP5PB | ATP synthase peripheral stalk-membrane subunit b | [
"P24539"
] | 1 | 111448864-111462773 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046067",
"HPA057347"
] | [
"ATP5F1"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Hydrogen ion transport",
"Ion transport",
"Transport"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 113 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 37: Non-specific - mRNA processing | Cluster 97: Non-specific - Cellular respiration | Cluster 41: Striated muscle - Muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 4,527 | 9 |
ENSG00000116473 | RAP1A | RAP1A, member of RAS oncogene family | [
"P62834"
] | 1 | 111542218-111716691 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"KREV-1",
"SMGP21"
] | [
"Enzymes",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Neurogenesis"
] | [
"Hydrolase"
] | [
"Tumor suppressor"
] | [] | [] | [] | [] | null | null | null | 21 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 21: Lymphoma - Adaptive immune response | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,528 | 9 |
ENSG00000116478 | HDAC1 | Histone deacetylase 1 | [
"Q13547"
] | 1 | 32292083-32333635 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005017",
"HPA029693",
"CAB068191"
] | [
"GON-10",
"HD1",
"KDAC1",
"RPD3L1"
] | [
"Enzymes",
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Hydrolase",
"Repressor"
] | [
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 662 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 39: Astrocytes - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,529 | 9 |
ENSG00000116489 | CAPZA1 | Capping actin protein of muscle Z-line subunit alpha 1 | [
"P52907"
] | 1 | 112619805-112671616 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB045963"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin capping",
"Actin-binding"
] | [] | [] | [] | [] | [] | null | Approved | null | 80 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 20: Macrophages & Microglia - Immune response | Cluster 37: Non-specific - mRNA processing | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Colon Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 4,530 | 9 |
ENSG00000116497 | S100PBP | S100P binding protein | [
"Q96BU1"
] | 1 | 32816767-32858875 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027242",
"HPA027328"
] | [
"FLJ12903",
"S100PBPR"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nuclear speckles"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 4 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 25: Non-specific - Transcription | Cluster 51: Myeloma - Immunoglobulins | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,531 | 2 |
ENSG00000116514 | RNF19B | Ring finger protein 19B | [
"Q6ZMZ0"
] | 1 | 32936445-32964809 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049587",
"HPA063640"
] | [
"FLJ90005",
"IBRDC3",
"NKLAM"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Adaptive immunity",
"Immunity",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 33 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 25: Non-specific - Transcription | Cluster 46: Lymphoma - Humoral immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 39: Testis - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,532 | 3 |
ENSG00000116521 | SCAMP3 | Secretory carrier membrane protein 3 | [
"O14828"
] | 1 | 155255979-155262430 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA071167"
] | [
"C1orf3"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | null | null | 15 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 28: Oligodendrocytes - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 4,533 | 5 |
ENSG00000116525 | TRIM62 | Tripartite motif containing 62 | [
"Q9BVG3"
] | 1 | 33145399-33182059 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA050061"
] | [
"DEAR1",
"FLJ10759"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Immunity",
"Innate immunity",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Vesicles",
"Focal adhesion sites"
] | [] | [] | [] | Approved | null | null | 18 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 11: Neuronal - Sensory perception | Cluster 22: Non-specific - Basic cellular functions | Cluster 2: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 4,534 | 5 |
ENSG00000116539 | ASH1L | ASH1 like histone lysine methyltransferase | [
"Q9NR48"
] | 1 | 155335268-155563162 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA004806"
] | [
"ASH1",
"ASH1L1",
"huASH1",
"KMT2H"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Chromatin regulator",
"Methyltransferase",
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm",
"Golgi apparatus"
] | [
"Nuclear bodies"
] | [] | [] | Approved | Approved | null | 8 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 34: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 7: Non-specific - Transcription | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,535 | 8 |
ENSG00000116560 | SFPQ | Splicing factor proline and glutamine rich | [
"P23246"
] | 1 | 35176378-35193446 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009886",
"HPA047513",
"HPA054689"
] | [
"PPP1R140",
"PSF"
] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"DNA damage",
"DNA recombination",
"DNA repair",
"Immunity",
"Innate immunity",
"mRNA processing",
"mRNA splicing",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor",
"RNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 114 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 55: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 20: Non-specific - Transcription regulation | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,537 | 7 |
ENSG00000116580 | GON4L | Gon-4 like | [
"Q3T8J9"
] | 1 | 155749659-155859400 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006986",
"HPA057305",
"HPA074504"
] | [
"FLJ20203",
"GON-4",
"GON4",
"YARP"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [] | [] | [] | Enhanced | Uncertain | null | 6 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 45: Non-specific - Nuclear processes | Cluster 7: Non-specific - Transcription | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,539 | 2 |
ENSG00000116584 | ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2 | [
"Q92974"
] | 1 | 155946851-156007070 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043437"
] | [
"GEF-H1",
"GEFH1",
"KIAA0651",
"Lfc",
"LFP40",
"P40"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Differentiation",
"Immunity",
"Innate immunity",
"Mitosis",
"Neurogenesis"
] | [
"Developmental protein",
"Guanine-nucleotide releasing factor"
] | [
"Intellectual disability"
] | [] | [] | [] | [] | null | Approved | null | 62 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 30: White matter - Myelination | Cluster 51: Myeloma - Immunoglobulins | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 5: Spleen - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,540 | 8 |
ENSG00000116586 | LAMTOR2 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 | [
"Q9Y2Q5"
] | 1 | 156054782-156058506 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA004126"
] | [
"ENDAP",
"MAPBPIP",
"MAPKSP1AP",
"p14",
"Ragulator2",
"ROBLD3"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 49 | No | No | Cluster 29: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 45: Non-specific - Nuclear processes | Cluster 97: Non-specific - Cellular respiration | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,541 | 2 |
ENSG00000116604 | MEF2D | Myocyte enhancer factor 2D | [
"Q14814"
] | 1 | 156463727-156500779 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004807",
"HPA007114"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Apoptosis",
"Differentiation",
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Enhanced | Enhanced | null | 13 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,542 | 1 |
ENSG00000116641 | DOCK7 | Dedicator of cytokinesis 7 | [
"Q96N67"
] | 1 | 62454298-62688386 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"KIAA1771",
"ZIR2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein",
"Guanine-nucleotide releasing factor"
] | [
"Epilepsy"
] | [] | [] | [] | [] | null | null | null | 51 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 39: Astrocytes - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,543 | 3 |
ENSG00000116649 | SRM | Spermidine synthase | [
"P19623"
] | 1 | 11054584-11060020 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA015746"
] | [
"SPS1",
"SRML1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Polyamine biosynthesis",
"Spermidine biosynthesis"
] | [
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 38: Sub-cortical - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 4 | 2 | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,544 | 4 |
ENSG00000116661 | FBXO2 | F-box protein 2 | [
"Q9UK22"
] | 1 | 11637018-11655785 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005472"
] | [
"Fbg1",
"Fbs1",
"FBX2",
"Nfb42",
"OCP1"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 171 | null | null | Cluster 24: Non-specific - Transcription | Cluster 19: Astrocytes - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Colon Adenocarcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | 4,545 | 3 |
ENSG00000116668 | SWT1 | SWT1 RNA endoribonuclease homolog | [
"Q5T5J6"
] | 1 | 185157080-185291781 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA024214",
"HPA027334"
] | [
"C1orf26",
"FLJ20121",
"HsSwt1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | null | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,548 | 6 |
ENSG00000116670 | MAD2L2 | Mitotic arrest deficient 2 like 2 | [
"Q9UI95"
] | 1 | 11658918-11691811 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003882",
"CAB008110"
] | [
"FANCV",
"MAD2B",
"POLZ2",
"REV7"
] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA damage",
"DNA repair",
"Mitosis",
"Transcription",
"Transcription regulation"
] | [] | [
"Cancer-related genes",
"Disease variant",
"Fanconi anemia"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 186 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 35: RS4;11 - Unknown function | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 4,549 | 6 |
ENSG00000116675 | DNAJC6 | DnaJ heat shock protein family (Hsp40) member C6 | [
"O75061"
] | 1 | 65248219-65415871 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031182",
"HPA054917"
] | [
"KIAA0473",
"PARK19"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Chaperone",
"Hydrolase",
"Protein phosphatase"
] | [
"Disease variant",
"Neurodegeneration",
"Parkinson disease",
"Parkinsonism"
] | [
"Cytosol"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | Approved | Enhanced | null | 6 | null | null | null | Cluster 28: Oligodendrocytes - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Group enriched | Detected in many | 6 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,550 | 2 |
ENSG00000116678 | LEPR | Leptin receptor | [
"P48357"
] | 1 | 65420652-65641559 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030899"
] | [
"CD295",
"OBR"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"CD markers",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [
"Cancer-related genes",
"FDA approved drug targets",
"Obesity"
] | [
"Vesicles"
] | [
"Plasma membrane",
"Primary cilium",
"Basal body",
"Cytosol"
] | [
"Intracellular and membrane"
] | [
"Receptor"
] | Approved | Approved | Supported | 7 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 36: Choroid plexus - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 108: Fibroblasts - ECM organization | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Cancer enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,551 | 1 |
ENSG00000116679 | IVNS1ABP | Influenza virus NS1A binding protein | [
"Q9Y6Y0"
] | 1 | 185296388-185317273 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003405"
] | [
"ARA3",
"HSPC068",
"KIAA0850",
"KLHL39",
"ND1",
"NS-1",
"NS1-BP"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 21 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,552 | 6 |
ENSG00000116685 | KIAA2013 | KIAA2013 | [
"Q8IYS2"
] | 1 | 11919591-11926428 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA052677",
"HPA060536"
] | [
"MGC33867",
"RP5-1077B9.1"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 4 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 27: Non-specific - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,553 | 4 |
ENSG00000116688 | MFN2 | Mitofusin 2 | [
"O95140"
] | 1 | 11980181-12015211 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030554",
"CAB079902"
] | [
"CMT2A2",
"CPRP1",
"KIAA0214",
"MARF"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Apoptosis",
"Autophagy",
"Unfolded protein response"
] | [
"Hydrolase"
] | [
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Uncertain | null | 25 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 19: Astrocytes - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 41: Striated muscle - Muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 4,554 | 3 |
ENSG00000116690 | PRG4 | Proteoglycan 4 | [
"Q92954"
] | 1 | 186296279-186314567 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB054258"
] | [
"bG174L6.2",
"CACP",
"FLJ32635",
"HAPO",
"JCAP",
"MSF",
"SZP"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | null | Supported | null | null | null | null | Cluster 16: Non-specific - Cell proliferation | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 44: Connective tissue cells - ECM organization | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in some | 18 | Cancer enriched | Detected in many | 4 | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 5 | 0 | 0 | 0 | [] | [] | [] | 4,555 | 5 |
ENSG00000116691 | MIIP | Migration and invasion inhibitory protein | [
"Q5JXC2"
] | 1 | 12019466-12032045 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044948"
] | [
"FLJ12438",
"IIp45"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 38 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 27: Non-specific - Mixed function | Cluster 21: Lymphoma - Adaptive immune response | Cluster 4: Breast lactating luminal cells - Lactation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Glioblastoma Multiforme"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,556 | 4 |
ENSG00000116698 | SMG7 | SMG7 nonsense mediated mRNA decay factor | [
"Q92540"
] | 1 | 183472216-183598246 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029350",
"HPA076314"
] | [
"C1orf16",
"EST1C",
"KIAA0250",
"SGA56M",
"SMG-7"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Nonsense-mediated mRNA decay"
] | [] | [] | [
"Nucleoli",
"Cytosol"
] | [
"Nuclear speckles",
"Vesicles",
"Basal body"
] | [] | [] | Supported | Supported | null | 22 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 16: Non-specific - Transcription | Cluster 45: Non-specific - Nuclear processes | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 4,557 | 1 |
ENSG00000116701 | NCF2 | Neutrophil cytosolic factor 2 | [
"P19878"
] | 1 | 183554461-183590905 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002327",
"HPA006040",
"CAB022160"
] | [
"NOXA2",
"p67phox"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Chronic granulomatous disease",
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 22 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 12: Non-specific - Vasculature | Cluster 55: Lymphoma - Immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Immune cell enhanced | Detected in many | null | 3 | 0 | 3 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 4,558 | 6 |
ENSG00000116703 | PDC | Phosducin | [
"P20941"
] | 1 | 186443566-186461114 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA062235"
] | [
"MEKA"
] | [
"Predicted intracellular proteins"
] | [
"Sensory transduction",
"Vision"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 2 | null | null | null | Cluster 34: Non-specific - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in single | 1,642 | Cancer enriched | Detected in some | 6 | Not detected | Not detected | null | Group enriched | Detected in many | 22 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,559 | 7 |
ENSG00000116704 | SLC35D1 | Solute carrier family 35 member D1 | [
"Q9NTN3"
] | 1 | 66999350-67054148 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"KIAA0260",
"UGTREL7"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Sugar transport",
"Transport"
] | [] | [
"Disease variant",
"Dwarfism"
] | [] | [] | [] | [] | null | null | null | null | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 42: Choroid plexus - Mitochondria | Cluster 46: Lymphoma - Humoral immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Uterine Corpus Endometrial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 4,560 | 7 |
ENSG00000116711 | PLA2G4A | Phospholipase A2 group IVA | [
"P47712"
] | 1 | 186828949-186988981 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010050",
"HPA050062",
"HPA054206"
] | [
"cPLA2-alpha",
"PLA2G4"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Fatty acid biosynthesis",
"Fatty acid metabolism",
"Glycerol metabolism",
"Leukotriene biosynthesis",
"Lipid biosynthesis",
"Lipid degradation",
"Lipid metabolism",
"Phospholipid degradation",
"Phospholipid metabolism",
"Prostaglandin biosynthesis",
"Prostaglandin metabolism"
] | [
"Hydrolase"
] | [
"Disease variant"
] | [
"Cytosol"
] | [
"Vesicles"
] | [] | [] | Supported | Approved | null | 20 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 49: Hindbrain - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 69: Parathyroid gland - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 6 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 4,561 | 8 |
ENSG00000116717 | GADD45A | Growth arrest and DNA damage inducible alpha | [
"P24522"
] | 1 | 67685201-67688334 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053420"
] | [
"DDIT1",
"GADD45"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"DNA damage",
"Growth arrest"
] | [] | [
"Cancer-related genes"
] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | null | null | 37 | null | Yes | Cluster 19: Eosinophils - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,562 | 1 |
ENSG00000116721 | PRAMEF1 | PRAME family member 1 | [
"O95521"
] | 1 | 12791397-12796628 | Evidence at transcript level | No human protein/transcript evidence | Evidence at transcript level | Evidence at transcript level | [] | [] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | null | Cluster 12: Bone cancer - Neuronal signaling | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | null | Not detected | Not detected | null | Cancer enriched | Detected in single | 22 | Not detected | Not detected | null | Group enriched | Detected in some | 44 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,563 | 4 |
ENSG00000116726 | PRAMEF12 | PRAME family member 12 | [
"O95522"
] | 1 | 12773738-12777906 | No human protein/transcript evidence | No human protein/transcript evidence | No human protein/transcript evidence | No human protein/transcript evidence | [
"HPA045286",
"HPA051704"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Uncertain | Uncertain | null | null | null | null | null | null | Cluster 27: Breast cancer - Unknown function | null | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,564 | 6 |
ENSG00000116729 | WLS | Wnt ligand secretion mediator | [
"Q5T9L3"
] | 1 | 68098473-68233120 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA069520"
] | [
"C1orf139",
"EVI",
"FLJ23091",
"GPR177",
"mig-14",
"MRP"
] | [
"Disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Wnt signaling pathway"
] | [
"Developmental protein"
] | [
"Disease variant"
] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 14 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 39: Astrocytes - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 8 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,565 | 9 |
ENSG00000116731 | PRDM2 | PR/SET domain 2 | [
"Q13029"
] | 1 | 13700188-13825079 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA005809"
] | [
"HUMHOXY1",
"KMT8",
"KMT8A",
"MTB-ZF",
"RIZ",
"RIZ1",
"RIZ2"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Methyltransferase",
"Transferase"
] | [] | [
"Nucleoplasm",
"Golgi apparatus"
] | [] | [] | [] | Approved | Approved | null | 7 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 53: Neurons - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 4,566 | 1 |
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