ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000115211 | EIF2B4 | Eukaryotic translation initiation factor 2B subunit delta | [
"Q9UI10"
] | 2 | 27364352-27370338 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB032234",
"HPA068855"
] | [
"DKFZP586J0119",
"EIF-2B",
"EIF2B",
"EIF2Bdelta"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Initiation factor"
] | [
"Disease variant",
"Leukodystrophy"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Approved | null | 22 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 45: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 4,337 | 4 |
ENSG00000115216 | NRBP1 | Nuclear receptor binding protein 1 | [
"Q9UHY1"
] | 2 | 27427790-27442259 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029527",
"CAB033078"
] | [
"BCON3",
"MADM",
"MUDPNP",
"NRBP"
] | [
"Enzymes",
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Supported | null | 42 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 44: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,338 | 2 |
ENSG00000115221 | ITGB6 | Integrin subunit beta 6 | [
"P18564"
] | 2 | 160099667-160200313 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA023626",
"CAB073536"
] | [] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Host-virus interaction"
] | [
"Host cell receptor for virus entry",
"Integrin",
"Receptor"
] | [
"Amelogenesis imperfecta",
"Cancer-related genes",
"Disease variant"
] | [
"Nucleoplasm",
"Cell Junctions",
"Acrosome"
] | [
"Centrosome",
"Connecting piece",
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | Approved | Approved | null | 3 | null | null | null | null | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,339 | 4 |
ENSG00000115226 | FNDC4 | Fibronectin type III domain containing 4 | [
"Q9H6D8"
] | 2 | 27491883-27495200 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA051804",
"HPA063581"
] | [
"FLJ22362",
"FRCP1"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Aggresome",
"Cytosol"
] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Approved | Uncertain | null | null | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 7: Liver cancer - Metabolism | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,340 | 6 |
ENSG00000115232 | ITGA4 | Integrin subunit alpha 4 | [
"P13612"
] | 2 | 181457202-181538940 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA074961"
] | [
"CD49D"
] | [
"Cancer-related genes",
"CD markers",
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [
"Integrin",
"Receptor"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [] | [
"Intracellular and membrane"
] | [
"Receptor"
] | Approved | null | null | 10 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 35: Non-specific - DNA binding | Cluster 47: Leukemia - Hemostasis | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 51: Lymphoid tissue - Adaptive immune response | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 4,341 | 2 |
ENSG00000115233 | PSMD14 | Proteasome 26S subunit, non-ATPase 14 | [
"O00487"
] | 2 | 161308425-161411717 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002114",
"HPA003828"
] | [
"pad1",
"POH1",
"Rpn11"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 134 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 27: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [] | [
"Bladder Urothelial Carcinoma",
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 4,342 | 4 |
ENSG00000115234 | SNX17 | Sorting nexin 17 | [
"Q15036"
] | 2 | 27370496-27377535 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043867"
] | [
"KIAA0064"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Enhanced | Supported | null | 17 | No | No | Cluster 29: Non-specific - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,343 | 3 |
ENSG00000115241 | PPM1G | Protein phosphatase, Mg2+/Mn2+ dependent 1G | [
"O15355"
] | 2 | 27381195-27409591 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035530",
"HPA035531"
] | [
"PP2CG",
"PP2Cgamma"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 108 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 21: Non-specific - Metabolism | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 39: Testis - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in all | 6 | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 4,345 | 5 |
ENSG00000115252 | PDE1A | Phosphodiesterase 1A | [
"P54750"
] | 2 | 182139968-182523359 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA022151"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Calmodulin-binding",
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | null | null | null | null | Cluster 34: Non-specific - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 4,346 | 5 |
ENSG00000115257 | PCSK4 | Proprotein convertase subtilisin/kexin type 4 | [
"Q6UW60"
] | 19 | 1481428-1490752 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA005572"
] | [
"DKFZp434B217",
"MGC34749",
"PC4",
"SPC5"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in many | 9 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,348 | 4 |
ENSG00000115263 | GCG | Glucagon | [
"P01275"
] | 2 | 162142882-162152404 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000040",
"HPA036760",
"HPA036761"
] | [
"GLP-1",
"GLP1",
"GLP2",
"GRPP"
] | [
"Predicted secreted proteins"
] | [] | [
"Hormone"
] | [] | [
"Endoplasmic reticulum"
] | [
"Vesicles"
] | [
"Secreted to blood"
] | [
"Hormone"
] | Approved | Enhanced | null | 10 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 8: Pancreas - Proteolysis | Tissue enriched | Detected in many | 13 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in some | 167 | Cell type enriched | Detected in some | 19 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,349 | 1 |
ENSG00000115266 | APC2 | APC regulator of WNT signaling pathway 2 | [
"O95996"
] | 19 | 1446302-1473244 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA078002"
] | [
"APCL"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Wnt signaling pathway"
] | [] | [
"Disease variant",
"Intellectual disability",
"Lissencephaly"
] | [
"Cytokinetic bridge"
] | [
"Midbody",
"Primary cilium",
"Cytosol"
] | [] | [] | Supported | null | null | 6 | Yes | No | null | Cluster 19: Astrocytes - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in some | 8 | Group enriched | Detected in many | 7 | Cancer enriched | Detected in some | 28 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,350 | 7 |
ENSG00000115267 | IFIH1 | Interferon induced with helicase C domain 1 | [
"Q9BYX4"
] | 2 | 162267074-162318684 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002656"
] | [
"Hlcd",
"IDDM19",
"MDA-5",
"MDA5"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"Host-virus interaction",
"Immunity",
"Innate immunity"
] | [
"Helicase",
"Hydrolase",
"RNA-binding"
] | [
"Aicardi-Goutieres syndrome",
"Diabetes mellitus",
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | 16 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 43: Hindbrain - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,351 | 2 |
ENSG00000115268 | RPS15 | Ribosomal protein S15 | [
"P62841"
] | 19 | 1438358-1440495 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054510",
"HPA057793"
] | [
"MGC111130",
"RIG",
"S15"
] | [
"Cancer-related genes",
"Essential proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [
"Cancer-related genes"
] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 129 | null | null | Cluster 18: Non-specific - Translation | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,352 | 8 |
ENSG00000115271 | GCA | Grancalcin | [
"P28676"
] | 2 | 162318840-162371595 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035033",
"HPA035034"
] | [
"GCL"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Supported | Enhanced | null | 14 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 30: White matter - Myelination | Cluster 10: Ciliated cells - Ion channel activity | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 9 | Group enriched | Detected in all | 5 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,353 | 3 |
ENSG00000115274 | INO80B | INO80 complex subunit B | [
"Q9C086"
] | 2 | 74455087-74457944 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA070644",
"HPA078274"
] | [
"hIes2",
"HMGA1L4",
"HMGIYL4",
"IES2",
"PAP-1BP",
"PAPA-1",
"ZNHIT4"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA recombination",
"DNA repair",
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Nuclear bodies"
] | [] | [] | Supported | null | null | 83 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 4,354 | 4 |
ENSG00000115275 | MOGS | Mannosyl-oligosaccharide glucosidase | [
"Q13724"
] | 2 | 74461057-74465410 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011322",
"HPA011969"
] | [
"CWH41",
"DER7",
"GCS1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosidase",
"Hydrolase"
] | [
"Disease variant"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Approved | null | 9 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 27: Non-specific - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 8: Non-specific - Secretory pathway | Cluster 60: Stomach - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Lung Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 4,355 | 5 |
ENSG00000115282 | TTC31 | Tetratricopeptide repeat domain 31 | [
"Q49AM3"
] | 2 | 74483073-74494559 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041783"
] | [
"FLJ12788"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 1 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 30: White matter - Myelination | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 26: Kidney & Intestine - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 4,356 | 1 |
ENSG00000115289 | PCGF1 | Polycomb group ring finger 1 | [
"Q9BSM1"
] | 2 | 74505043-74507695 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011356",
"HPA069156"
] | [
"MGC10882",
"NSPC1",
"RNF68"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 47 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 31: Non-specific - Transcription | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 41: Oocytes - Oogenesis | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 4,358 | 7 |
ENSG00000115290 | GRB14 | Growth factor receptor bound protein 14 | [
"Q14449"
] | 2 | 164492417-164621482 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022294",
"HPA035052",
"HPA035053"
] | [] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 7 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,359 | 8 |
ENSG00000115295 | CLIP4 | CAP-Gly domain containing linker protein family member 4 | [
"Q8N3C7"
] | 2 | 29097705-29199777 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043366",
"HPA056246"
] | [
"FLJ21069",
"RSNL2"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | 15 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 28: Oligodendrocytes - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 4,360 | 3 |
ENSG00000115297 | TLX2 | T cell leukemia homeobox 2 | [
"O43763"
] | 2 | 74513463-74517148 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA062254"
] | [
"Enx",
"HOX11L1",
"NCX"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | null | 13 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in some | 43 | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Rectum Adenocarcinoma"
] | [
"Rectum Adenocarcinoma"
] | 4,361 | 4 |
ENSG00000115306 | SPTBN1 | Spectrin beta, non-erythrocytic 1 | [
"Q01082"
] | 2 | 54456317-54671446 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012685",
"HPA013149"
] | [] | [
"Disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [] | [
"Actin capping",
"Actin-binding",
"Calmodulin-binding"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Cytosol"
] | [] | [] | [] | Uncertain | Supported | null | 52 | null | Yes | Cluster 43: Non-specific - Transcription & Translation | Cluster 19: Astrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 43: Placenta - Pregnancy hormone signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 4,362 | 5 |
ENSG00000115310 | RTN4 | Reticulon 4 | [
"Q9NQC3"
] | 2 | 54972187-55112621 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005388",
"HPA023977"
] | [
"ASY",
"KIAA0886",
"NOGO",
"NSP-CL"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Neurogenesis"
] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Enhanced | Supported | null | 147 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 4,364 | 4 |
ENSG00000115317 | HTRA2 | HtrA serine peptidase 2 | [
"O43464"
] | 2 | 74529596-74533350 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004004",
"HPA006602",
"HPA027366"
] | [
"OMI",
"PARK13",
"PRSS25"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Apoptosis"
] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Disease variant",
"Epilepsy",
"Neurodegeneration",
"Parkinson disease",
"Parkinsonism"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Uncertain | null | 101 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 27: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,365 | 8 |
ENSG00000115325 | DOK1 | Docking protein 1 | [
"Q99704"
] | 2 | 74549026-74557551 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004224",
"HPA048561"
] | [
"p62dok"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 22 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 44: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 47: Platelets - Hemostasis | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,367 | 5 |
ENSG00000115339 | GALNT3 | Polypeptide N-acetylgalactosaminyltransferase 3 | [
"Q14435"
] | 2 | 165747588-165794659 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007613"
] | [
"GalNAc-T3",
"HFTC",
"HHS"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [
"Disease variant"
] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | Enhanced | null | 2 | null | null | Cluster 32: Basophils - Transcription | Cluster 39: Astrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 3 | 0 | 3 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma"
] | 4,368 | 9 |
ENSG00000115350 | POLE4 | DNA polymerase epsilon 4, accessory subunit | [
"Q9NR33"
] | 2 | 74958643-74970128 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054979",
"HPA071815",
"HPA076606"
] | [
"p12"
] | [
"FDA approved drug targets",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"DNA-binding"
] | [
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | Approved | null | 20 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 33: Neurons - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 4,369 | 7 |
ENSG00000115353 | TACR1 | Tachykinin receptor 1 | [
"P25103"
] | 2 | 75046463-75199520 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055565",
"HPA074573"
] | [
"NK1R",
"NKIR",
"SPR",
"TAC1R"
] | [
"FDA approved drug targets",
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"FDA approved drug targets"
] | [
"Plasma membrane",
"Centrosome",
"Basal body"
] | [] | [] | [] | Approved | Enhanced | null | 14 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 72: Neuronal - Signal transduction | Cluster 109: Neurons - Neuronal signaling | Cluster 74: Non-specific - Signal transduction | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 4 | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 23 | 2 | 0 | 2 | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme"
] | [] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme"
] | 4,370 | 1 |
ENSG00000115355 | CCDC88A | Coiled-coil domain containing 88A | [
"Q3V6T2"
] | 2 | 55287842-55419895 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038101",
"HPA038102"
] | [
"APE",
"FLJ10392",
"GIV",
"GRDN",
"HkRP1",
"KIAA1212"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation",
"Neurogenesis"
] | [
"Guanine-nucleotide releasing factor"
] | [
"Epilepsy",
"Intellectual disability",
"Neurodegeneration"
] | [
"Nucleoplasm",
"Centrosome",
"Basal body"
] | [
"Plasma membrane"
] | [] | [] | Supported | Enhanced | null | 21 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,371 | 3 |
ENSG00000115363 | EVA1A | Eva-1 homolog A, regulator of programmed cell death | [
"Q9H8M9"
] | 2 | 75469302-75569722 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008055"
] | [
"FAM176A",
"FLJ13391",
"TMEM166"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Apoptosis",
"Autophagy"
] | [] | [] | [
"Vesicles"
] | [
"Plasma membrane"
] | [] | [] | Supported | Approved | null | 5 | null | Yes | null | Cluster 43: Hindbrain - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 8 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme"
] | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 4,373 | 7 |
ENSG00000115364 | MRPL19 | Mitochondrial ribosomal protein L19 | [
"P49406"
] | 2 | 75646783-75690851 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046805",
"HPA056622"
] | [
"KIAA0104",
"MRP-L15",
"RLX1",
"RPML15"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Approved | null | 44 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 28: Oligodendrocytes - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,374 | 3 |
ENSG00000115365 | LANCL1 | LanC like glutathione S-transferase 1 | [
"O43813"
] | 2 | 210427131-210477652 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034994"
] | [
"GPR69A",
"p40"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Transferase"
] | [] | [
"Microtubules",
"Primary cilium",
"Basal body",
"End piece"
] | [
"Flagellar centriole"
] | [] | [] | Approved | Enhanced | null | 23 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 28: Oligodendrocytes - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,375 | 8 |
ENSG00000115368 | WDR75 | WD repeat domain 75 | [
"Q8IWA0"
] | 2 | 189441446-189475552 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"FLJ12519",
"NET16",
"UTP17"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis",
"rRNA processing",
"Transcription",
"Transcription regulation"
] | [] | [] | [] | [] | [] | [] | null | null | null | 20 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 34: Non-specific - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 17: Non-specific - RNA processing | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,376 | 7 |
ENSG00000115380 | EFEMP1 | EGF containing fibulin extracellular matrix protein 1 | [
"Q12805"
] | 2 | 55865967-55924139 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016368",
"HPA049806",
"HPA070841",
"HPA071588"
] | [
"DHRD",
"FBLN3",
"FBNL",
"MTLV",
"S1-5"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Growth factor"
] | [
"Disease variant",
"Glaucoma"
] | [
"Mitochondria"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Growth factor"
] | Supported | Supported | null | 42 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 4,377 | 6 |
ENSG00000115386 | REG1A | Regenerating family member 1 alpha | [
"P05451"
] | 2 | 79120362-79123409 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025138",
"HPA045549",
"HPA045579"
] | [
"PSP",
"PSPS",
"PSPS1",
"PTP",
"REG"
] | [
"Plasma proteins",
"Predicted secreted proteins",
"Transporters"
] | [] | [] | [] | [] | [] | [
"Secreted to digestive system"
] | [
"No annotated function"
] | null | Enhanced | null | 2 | null | null | null | null | Cluster 27: Breast cancer - Unknown function | Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion | Cluster 8: Pancreas - Proteolysis | Tissue enriched | Detected in many | 15 | Group enriched | Detected in some | 47 | Group enriched | Detected in many | 5 | Cell type enriched | Detected in some | 11 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,378 | 7 |
ENSG00000115392 | FANCL | FA complementation group L | [
"Q9NW38"
] | 2 | 58159243-58241410 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB033842",
"HPA036685",
"HPA036686"
] | [
"FAAP43",
"FLJ10335",
"PHF9",
"Pog"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Fanconi anemia"
] | [
"Nuclear bodies"
] | [
"Vesicles"
] | [] | [] | Approved | Supported | null | 60 | null | Yes | Cluster 14: Non-specific - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 4,379 | 3 |
ENSG00000115414 | FN1 | Fibronectin 1 | [
"P02751"
] | 2 | 215360440-215436073 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000126",
"HPA027066"
] | [
"CIG",
"FINC",
"GFND2",
"LETS",
"MSF"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Acute phase",
"Angiogenesis",
"Cell adhesion",
"Cell shape"
] | [
"Heparin-binding"
] | [
"Cancer-related genes",
"Disease variant",
"Dwarfism",
"FDA approved drug targets"
] | [] | [] | [
"Secreted to blood"
] | [
"Acute phase"
] | null | Enhanced | null | 59 | null | null | null | Cluster 12: Non-specific - Vasculature | Cluster 64: Connective tissue cells - ECM organization | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Stomach Adenocarcinoma"
] | 4,380 | 8 |
ENSG00000115415 | STAT1 | Signal transducer and activator of transcription 1 | [
"P42224"
] | 2 | 190908460-191020960 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000931",
"HPA000982",
"CAB004049"
] | [
"ISGF-3",
"STAT91"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Antiviral defense",
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Disease variant"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 93 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 22: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 18: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,381 | 8 |
ENSG00000115419 | GLS | Glutaminase | [
"O94925"
] | 2 | 190880821-190965552 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036223"
] | [
"GAC",
"GAM",
"GLS1",
"KGA",
"KIAA0838"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [
"Cataract",
"Disease variant",
"Epilepsy"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 21 | No | No | Cluster 5: Non-specific - Cell proliferation | Cluster 24: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 20: Non-specific - Transcription regulation | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,382 | 6 |
ENSG00000115421 | PAPOLG | Poly(A) polymerase gamma | [
"Q9BWT3"
] | 2 | 60756253-60802086 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017795",
"HPA035349",
"HPA035350"
] | [
"FLJ12972"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"mRNA processing"
] | [
"RNA-binding",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Cytosol"
] | [] | [] | Supported | Approved | null | 6 | No | No | Cluster 35: Neutrophils - Protein binding | Cluster 9: Non-specific - Receptor signaling | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Lung Squamous Cell Carcinoma"
] | [] | [
"Lung Squamous Cell Carcinoma"
] | 4,383 | 1 |
ENSG00000115423 | DNAH6 | Dynein axonemal heavy chain 6 | [
"Q9C0G6"
] | 2 | 84516455-84819589 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA036391",
"HPA061401"
] | [
"Dnahc6",
"DNHL1",
"FLJ37357",
"HL-2"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Motor protein"
] | [] | [
"Plasma membrane",
"Centriolar satellite",
"Basal body",
"Connecting piece",
"Mid piece"
] | [
"Primary cilium tip",
"Calyx"
] | [] | [] | Approved | Enhanced | null | 4 | null | null | null | Cluster 17: Choroid plexus - Cilium | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Low cancer specificity | Detected in single | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,384 | 4 |
ENSG00000115425 | PECR | Peroxisomal trans-2-enoyl-CoA reductase | [
"Q9BY49"
] | 2 | 215996329-216082955 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021593",
"HPA022539"
] | [
"HSA250303",
"SDR29C1",
"TERP"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Fatty acid biosynthesis",
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid metabolism"
] | [
"Oxidoreductase"
] | [] | [
"Peroxisomes"
] | [] | [] | [] | Supported | Enhanced | null | 4 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 15: Kidney cancer - Membrane components | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 16: Liver & Kidney - Metabolism | Tissue enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,385 | 4 |
ENSG00000115446 | UNC50 | Unc-50 inner nuclear membrane RNA binding protein | [
"Q53HI1"
] | 2 | 98608579-98618515 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA027009"
] | [
"GMH1",
"UNCL",
"URP"
] | [
"Essential proteins",
"Predicted membrane proteins"
] | [] | [
"RNA-binding"
] | [] | [] | [] | [] | [] | null | Approved | null | 29 | null | null | Cluster 41: Basophils - Unknown function | Cluster 50: Non-specific - Nucleic acid binding | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 4,386 | 8 |
ENSG00000115457 | IGFBP2 | Insulin like growth factor binding protein 2 | [
"P18065"
] | 2 | 216632828-216664436 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA077723"
] | [
"IBP2"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Growth regulation"
] | [
"Growth factor binding"
] | [
"Cancer-related genes"
] | [
"Endoplasmic reticulum"
] | [] | [
"Secreted to blood"
] | [
"Other"
] | Approved | null | null | 5 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 49: HMC-1 - Innate immune response | Cluster 108: Fibroblasts - ECM organization | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 4,387 | 7 |
ENSG00000115459 | ELMOD3 | ELMO domain containing 3 | [
"Q96FG2"
] | 2 | 85354394-85391752 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012126"
] | [
"DFNB88",
"FLJ21977",
"RBED1",
"RBM29"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [
"Deafness",
"Non-syndromic deafness"
] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | Cluster 32: Basophils - Transcription | Cluster 13: Oligodendrocytes - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 89: Adipocytes - Lipid metabolism | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Thyroid Carcinoma"
] | [
"Thyroid Carcinoma"
] | 4,388 | 9 |
ENSG00000115461 | IGFBP5 | Insulin like growth factor binding protein 5 | [
"P24593"
] | 2 | 216672105-216695549 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040514",
"HPA070407"
] | [] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Growth factor binding"
] | [] | [
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Other"
] | Approved | null | Supported | 80 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 4,389 | 5 |
ENSG00000115464 | USP34 | Ubiquitin specific peptidase 34 | [
"Q70CQ2"
] | 2 | 61187463-61471087 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA025815"
] | [
"KIAA0570",
"KIAA0729"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway",
"Wnt signaling pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | 10 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 55: Non-specific - Transcription | Cluster 46: Lymphoma - Humoral immune response | Cluster 7: Non-specific - Transcription | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 4,390 | 5 |
ENSG00000115474 | KCNJ13 | Potassium inwardly rectifying channel subfamily J member 13 | [
"O60928"
] | 2 | 232765802-232776565 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051609"
] | [
"Kir1.4",
"Kir7.1",
"LCA16"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Ion channel",
"Voltage-gated channel"
] | [
"Cataract",
"Disease variant",
"Leber congenital amaurosis"
] | [
"Nuclear membrane"
] | [
"Plasma membrane"
] | [] | [] | Approved | null | null | null | null | null | Cluster 32: Basophils - Transcription | Cluster 36: Choroid plexus - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 1: Choroid plexus - Transmembrane transport | Group enriched | Detected in some | 8 | Cancer enhanced | Detected in single | null | Group enriched | Detected in some | 5 | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 4,392 | 1 |
ENSG00000115486 | GGCX | Gamma-glutamyl carboxylase | [
"P38435"
] | 2 | 85544720-85561532 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018284"
] | [
"VKCFD1"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Lyase"
] | [
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | 23 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 50: Non-specific - Nucleic acid binding | Cluster 45: Non-specific - Nuclear processes | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,394 | 9 |
ENSG00000115488 | NEU2 | Neuraminidase 2 | [
"Q9Y3R4"
] | 2 | 233032672-233035057 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB022336"
] | [
"SIAL2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism",
"Lipid degradation",
"Lipid metabolism"
] | [
"Glycosidase",
"Hydrolase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 14 | null | null | null | null | Cluster 53: Squamous epithelial cells - Keratinization | null | Cluster 37: Skin - Keratinization | Tissue enriched | Detected in single | 19 | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,395 | 2 |
ENSG00000115504 | EHBP1 | EH domain binding protein 1 | [
"Q8NDI1"
] | 2 | 62673851-63046487 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035468",
"HPA035469"
] | [
"KIAA0903",
"NACSIN"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Endocytosis",
"Protein transport",
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Enhanced | Enhanced | null | 5 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 38: Sub-cortical - Mixed function | Cluster 3: Rhabdoid - Membrane components | Cluster 89: Adipocytes - Lipid metabolism | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 4,396 | 8 |
ENSG00000115507 | OTX1 | Orthodenticle homeobox 1 | [
"P32242"
] | 2 | 63050057-63057836 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA052122"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 127 | null | null | Cluster 4: Neutrophils - Degranulation | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 5: Rhabdoid - Unknown function | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 2: Non-specific - Mixed function | Group enriched | Detected in some | 5 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 95 | 2 | 2 | 1 | [
"Lung Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Lung Squamous Cell Carcinoma"
] | 4,397 | 7 |
ENSG00000115514 | TXNDC9 | Thioredoxin domain containing 9 | [
"O14530"
] | 2 | 99318982-99340702 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031844",
"HPA031845",
"HPA031846"
] | [
"APACD"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 56 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 27: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 6 | 0 | 6 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,398 | 7 |
ENSG00000115520 | COQ10B | Coenzyme Q10B | [
"Q9H8M1"
] | 2 | 197453493-197475310 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA046057"
] | [
"FLJ13448"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | null | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 27: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Bladder Urothelial Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma"
] | 4,399 | 8 |
ENSG00000115523 | GNLY | Granulysin | [
"P22749"
] | 2 | 85685175-85698852 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025186",
"HPA058021"
] | [
"D2S69E",
"LAG-2",
"LAG2",
"NKG5",
"TLA519"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins",
"Transporters"
] | [] | [
"Antibiotic",
"Antimicrobial",
"Fungicide"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Defense"
] | null | Enhanced | null | 2 | null | null | Cluster 15: NK-cells - Unknown function | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 71: Lymphoma - Inflammatory response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 7 | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 6 | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Skin Cutaneous Melanoma"
] | [] | [
"Skin Cutaneous Melanoma"
] | 4,400 | 5 |
ENSG00000115524 | SF3B1 | Splicing factor 3b subunit 1 | [
"O75533"
] | 2 | 197388515-197435079 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050275"
] | [
"Hsh155",
"Prp10",
"PRPF10",
"SAP155",
"SF3b155"
] | [
"Cancer-related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"RNA-binding"
] | [
"Cancer-related genes"
] | [
"Nuclear speckles"
] | [] | [] | [] | Enhanced | Approved | null | 300 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 50: Non-specific - Nucleic acid binding | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 17: Non-specific - RNA processing | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,401 | 2 |
ENSG00000115526 | CHST10 | Carbohydrate sulfotransferase 10 | [
"O43529"
] | 2 | 100391860-100417668 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA012884",
"HPA051545"
] | [
"HNK-1ST"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Carbohydrate metabolism",
"Lipid metabolism",
"Steroid metabolism"
] | [
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 6 | null | null | Cluster 24: Non-specific - Transcription | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 5: Rhabdoid - Unknown function | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,403 | 1 |
ENSG00000115539 | PDCL3 | Phosducin like 3 | [
"Q9H2J4"
] | 2 | 100562993-100576739 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018469",
"HPA027094"
] | [
"VIAF1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Angiogenesis",
"Apoptosis"
] | [
"Chaperone"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | Approved | null | 81 | No | No | Cluster 12: Non-specific - Mitochondrial translation | Cluster 45: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 4,404 | 7 |
ENSG00000115540 | MOB4 | MOB family member 4, phocein | [
"Q9Y3A3"
] | 2 | 197515571-197553699 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB034082",
"HPA044125"
] | [
"2C4D",
"CGI-95",
"DKFZP564M112",
"MOB3",
"MOBKL3",
"PHOCN",
"PREI3"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 44 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 31: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,405 | 4 |
ENSG00000115541 | HSPE1 | Heat shock protein family E (Hsp10) member 1 | [
"P61604"
] | 2 | 197500140-197503449 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017366",
"HPA038755",
"HPA048272"
] | [
"CPN10",
"EPF",
"GroES",
"HSP10"
] | [
"Cancer-related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Stress response"
] | [
"Chaperone"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Supported | null | 21 | null | Yes | Cluster 30: Non-specific - DNA binding | Cluster 55: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 75: Non-specific - Chaperones and protein folding | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Prostate Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Prostate Adenocarcinoma"
] | 4,406 | 8 |
ENSG00000115548 | KDM3A | Lysine demethylase 3A | [
"Q9Y4C1"
] | 2 | 86440647-86492716 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055543",
"HPA065162"
] | [
"JHMD2A",
"JMJD1",
"JMJD1A",
"KIAA0742",
"TSGA"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Chromatin regulator",
"Dioxygenase",
"Oxidoreductase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 8 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 39: Astrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 40: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,407 | 2 |
ENSG00000115556 | PLCD4 | Phospholipase C delta 4 | [
"Q9BRC7"
] | 2 | 218607855-218637184 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009914",
"HPA038139",
"HPA038140"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid degradation",
"Lipid metabolism"
] | [
"Guanine-nucleotide releasing factor",
"Hydrolase",
"Transducer"
] | [] | [
"Cytosol"
] | [
"Endoplasmic reticulum",
"Plasma membrane"
] | [] | [] | Supported | Enhanced | null | 2 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 5: Rhabdoid - Unknown function | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 25: Non-specific - Basic cellular processes | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Uterine Corpus Endometrial Carcinoma"
] | [
"Glioblastoma Multiforme",
"Uterine Corpus Endometrial Carcinoma"
] | 4,408 | 6 |
ENSG00000115561 | CHMP3 | Charged multivesicular body protein 3 | [
"Q9Y3E7"
] | 2 | 86503430-86563479 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015673",
"HPA073383"
] | [
"CGI-149",
"NEDF",
"VPS24"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Cell cycle",
"Cell division",
"Protein transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Supported | null | 19 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 14: Neurons - Synaptic function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 15: Non-specific - Protein processing | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,409 | 6 |
ENSG00000115590 | IL1R2 | Interleukin 1 receptor type 2 | [
"P27930"
] | 2 | 101991960-102028544 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA027597",
"HPA027598"
] | [
"CD121b",
"IL1RB"
] | [
"Cancer-related genes",
"CD markers",
"Plasma proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [] | [
"Receptor"
] | [
"Cancer-related genes"
] | [] | [] | [
"Secreted to blood"
] | [
"Receptor"
] | null | Uncertain | null | 20 | null | null | Cluster 4: Neutrophils - Degranulation | Cluster 12: Non-specific - Vasculature | Cluster 71: Lymphoma - Inflammatory response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in many | 4 | Immune cell enriched | Detected in some | 26 | 4 | 0 | 4 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 4,411 | 4 |
ENSG00000115593 | SMYD1 | SET and MYND domain containing 1 | [
"Q8NB12"
] | 2 | 88067825-88113384 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA062282"
] | [
"BOP",
"KMT3D",
"ZMYND22"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Methyltransferase",
"Repressor",
"Transferase"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 39 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 55: Myocytes - Oxidative muscle function | Cluster 62: Skeletal muscle - Muscle contraction | Group enriched | Detected in some | 11 | Cancer enriched | Detected in single | 14 | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 9 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,413 | 6 |
ENSG00000115594 | IL1R1 | Interleukin 1 receptor type 1 | [
"P14778"
] | 2 | 102064544-102179874 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001237",
"HPA005823",
"CAB007779",
"HPA029560"
] | [
"CD121A",
"D2S1473",
"IL1R",
"IL1RA"
] | [
"Cancer-related genes",
"CD markers",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted membrane proteins",
"Predicted secreted proteins",
"Transporters"
] | [
"Inflammatory response"
] | [
"Hydrolase",
"Receptor"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets"
] | [
"Nucleoplasm",
"Vesicles"
] | [
"Plasma membrane",
"Cytosol"
] | [
"Secreted to blood"
] | [
"Receptor"
] | Approved | Approved | null | 13 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 12: Non-specific - Vasculature | Cluster 44: Connective tissue cells - ECM organization | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 6 | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 4,414 | 4 |
ENSG00000115596 | WNT6 | Wnt family member 6 | [
"Q9Y6F9"
] | 2 | 218859805-218874233 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA070759"
] | [] | [
"Predicted secreted proteins"
] | [
"Wnt signaling pathway"
] | [
"Developmental protein"
] | [] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Developmental protein"
] | null | Approved | null | null | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 110: Mural cells - ECM organization | Cluster 68: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in some | 4 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,415 | 8 |
ENSG00000115598 | IL1RL2 | Interleukin 1 receptor like 2 | [
"Q9HB29"
] | 2 | 102187006-102240002 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"IL-36R",
"IL1R-rp2",
"IL1RRP2"
] | [
"Enzymes",
"FDA approved drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Immunity",
"Inflammatory response",
"Innate immunity"
] | [
"Hydrolase",
"Receptor"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | null | null | 1 | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 4,416 | 5 |
ENSG00000115602 | IL1RL1 | Interleukin 1 receptor like 1 | [
"Q01638"
] | 2 | 102311502-102352037 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007406",
"HPA007917"
] | [
"DER4",
"FIT-1",
"IL33R",
"ST2",
"ST2L",
"ST2V",
"T1"
] | [
"Candidate cardiovascular disease genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Receptor"
] | [] | [
"Plasma membrane"
] | [
"Focal adhesion sites",
"Cytosol"
] | [
"Secreted to blood"
] | [
"Receptor"
] | Supported | Uncertain | null | 2 | null | null | Cluster 41: Basophils - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 49: HMC-1 - Innate immune response | Cluster 58: Mast cells - Allergic inflammatory responses | Cluster 14: Adipose tissue - Angiogenesis | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 5 | Group enriched | Detected in some | 64 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 4,417 | 5 |
ENSG00000115607 | IL18RAP | Interleukin 18 receptor accessory protein | [
"O95256"
] | 2 | 102418689-102452565 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025270"
] | [
"AcPL",
"CD218b"
] | [
"CD markers",
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Inflammatory response"
] | [
"Hydrolase",
"Receptor"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 1 | null | null | Cluster 24: Non-specific - Transcription | Cluster 12: Non-specific - Vasculature | Cluster 71: Lymphoma - Inflammatory response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in many | 9 | Group enriched | Detected in some | 20 | Low cancer specificity | Detected in some | null | Group enriched | Detected in some | 6 | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 4,419 | 6 |
ENSG00000115616 | SLC9A2 | Solute carrier family 9 member A2 | [
"Q9UBY0"
] | 2 | 102619553-102711355 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA035121",
"HPA035122"
] | [
"NHE2"
] | [
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Ion transport",
"Sodium transport",
"Transport"
] | [] | [] | [
"Cell Junctions"
] | [] | [] | [] | Supported | Approved | null | 2 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 32: Non-specific - Cell proliferation | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,420 | 3 |
ENSG00000115641 | FHL2 | Four and a half LIM domains 2 | [
"Q14192"
] | 2 | 105357712-105438513 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005922",
"HPA006028",
"CAB008368"
] | [
"DRAL",
"SLIM3"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Actin filaments",
"Focal adhesion sites"
] | [] | [] | [] | Enhanced | Enhanced | null | 193 | null | Yes | Cluster 35: Neutrophils - Protein binding | Cluster 53: Neurons - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 35: Non-specific - Mixed function | Group enriched | Detected in all | 8 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 3 | 0 | 3 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | 4,421 | 9 |
ENSG00000115652 | UXS1 | UDP-glucuronate decarboxylase 1 | [
"Q8NBZ7"
] | 2 | 106093308-106194301 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008825"
] | [
"FLJ23591",
"SDR6E1",
"UGD"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Decarboxylase",
"Lyase"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Uncertain | null | 2 | null | null | Cluster 6: T-cells - T-cell receptor | Cluster 38: Sub-cortical - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 72: Kidney - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,424 | 4 |
ENSG00000115657 | ABCB6 | ATP binding cassette subfamily B member 6 (Langereis blood group) | [
"Q9NP58"
] | 2 | 219209772-219218994 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046723",
"HPA058011"
] | [
"EST45597",
"MTABC3",
"umat"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [
"Translocase"
] | [
"Disease variant",
"Dyskeratosis congenita",
"Microphthalmia"
] | [
"Golgi apparatus"
] | [
"Nucleoplasm",
"Plasma membrane",
"Mitochondria",
"Cytosol",
"Mid piece",
"Principal piece"
] | [
"Intracellular and membrane"
] | [
"Transport"
] | Supported | Approved | null | null | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in some | 7 | Low immune cell specificity | Detected in some | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,425 | 5 |
ENSG00000115661 | STK16 | Serine/threonine kinase 16 | [
"O75716"
] | 2 | 219245455-219250337 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029450"
] | [
"MPSK",
"PKL12"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm",
"Nuclear bodies",
"Plasma membrane",
"Primary cilium",
"Primary cilium tip",
"Basal body"
] | [] | [] | Supported | Approved | null | 102 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 39: Astrocytes - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,426 | 9 |
ENSG00000115665 | SLC5A7 | Solute carrier family 5 member 7 | [
"Q9GZV3"
] | 2 | 107986523-108013994 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046105"
] | [
"CHT1",
"hCHT"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Neurotransmitter biosynthesis",
"Sodium transport",
"Symport",
"Transport"
] | [] | [
"Congenital myasthenic syndrome",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Cell Junctions",
"Intermediate filaments"
] | [
"Nuclear bodies"
] | [] | [] | Approved | null | null | 1 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in single | 11 | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Lung Squamous Cell Carcinoma"
] | [] | [
"Lung Squamous Cell Carcinoma"
] | 4,427 | 6 |
ENSG00000115685 | PPP1R7 | Protein phosphatase 1 regulatory subunit 7 | [
"Q15435"
] | 2 | 241149576-241183652 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034500",
"HPA034501"
] | [
"sds22"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli"
] | [] | [] | [] | Approved | Supported | null | 50 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 33: Neurons - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,429 | 7 |
ENSG00000115694 | STK25 | Serine/threonine kinase 25 | [
"O00506"
] | 2 | 241492670-241509730 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047147"
] | [
"SOK1",
"YSK1"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 70 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 51: Neurons - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,431 | 4 |
ENSG00000115705 | TPO | Thyroid peroxidase | [
"P07202"
] | 2 | 1374066-1543711 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007987",
"CAB009587",
"HPA073226"
] | [
"TPX"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Hydrogen peroxide",
"Thyroid hormones biosynthesis"
] | [
"Oxidoreductase",
"Peroxidase"
] | [
"Congenital hypothyroidism",
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Enhanced | null | null | null | null | Cluster 6: T-cells - T-cell receptor | Cluster 53: Neurons - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 33: Thyroid gland - Tissue development | Tissue enriched | Detected in many | 73 | Group enriched | Detected in some | 6 | Cancer enriched | Detected in some | 503 | Cell type enriched | Detected in some | 4 | Group enriched | Detected in some | 12 | 0 | 0 | 0 | [] | [] | [] | 4,432 | 7 |
ENSG00000115718 | PROC | Protein C, inactivator of coagulation factors Va and VIIIa | [
"P04070"
] | 2 | 127418427-127429242 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005550",
"CAB016721",
"CAB016792"
] | [] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Blood coagulation",
"Hemostasis"
] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets",
"Thrombophilia"
] | [] | [] | [
"Secreted to blood"
] | [
"Blood coagulation"
] | null | Approved | null | 2 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 26: Oligodendrocytes - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 31: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 41 | Cancer enriched | Detected in many | 6 | Cancer enriched | Detected in many | 7 | Cell type enriched | Detected in some | 9 | Immune cell enriched | Detected in some | 9 | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 4,433 | 1 |
ENSG00000115738 | ID2 | Inhibitor of DNA binding 2 | [
"Q02363"
] | 2 | 8678845-8684461 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA027612"
] | [
"bHLHb26",
"GIG8"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"Repressor"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Centrosome"
] | [] | [] | Approved | null | null | 47 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 82: Dendritic cells - Antigen presentation | Cluster 61: Non-specific - Transcription | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 4,434 | 9 |
ENSG00000115750 | TAF1B | TATA-box binding protein associated factor, RNA polymerase I subunit B | [
"Q53T94"
] | 2 | 9843443-9934416 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA071254"
] | [
"RAF1B",
"RAFI63",
"SL1",
"TAFI63"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Supported | null | null | 36 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,435 | 7 |
ENSG00000115756 | HPCAL1 | Hippocalcin like 1 | [
"P37235"
] | 2 | 10302889-10427617 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043245"
] | [
"BDR1",
"HLP2",
"VILIP-3"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Supported | null | 54 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 1: Neurons - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 71: Cerebellum - Nervous system development | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,436 | 2 |
ENSG00000115758 | ODC1 | Ornithine decarboxylase 1 | [
"P11926"
] | 2 | 10439968-10448327 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001536",
"CAB035996",
"HPA075384"
] | [
"ODC"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Polyamine biosynthesis"
] | [
"Decarboxylase",
"Lyase"
] | [
"Disease variant",
"FDA approved drug targets",
"Hypotrichosis"
] | [
"Golgi apparatus"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 7 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 21: Non-specific - Metabolism | Cluster 6: Leukemia - Signal transduction | Cluster 20: Non-specific - Transcription regulation | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,437 | 1 |
ENSG00000115761 | NOL10 | Nucleolar protein 10 | [
"Q9BSC4"
] | 2 | 10562347-10689987 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035286",
"HPA043075"
] | [
"FLJ14075",
"PQBP5"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli"
] | [] | [] | [] | Supported | Approved | null | 10 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 32: Cerebral cortex - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 17: Non-specific - RNA processing | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in single | null | 5 | 2 | 4 | [] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 4,439 | 2 |
ENSG00000115762 | PLEKHB2 | Pleckstrin homology domain containing B2 | [
"Q96CS7"
] | 2 | 131104847-131353709 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA075014"
] | [
"EVT2",
"FLJ20783"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 37 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 45: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 4,440 | 4 |
ENSG00000115806 | GORASP2 | Golgi reassembly stacking protein 2 | [
"Q9H8Y8"
] | 2 | 170928464-170967130 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035274",
"HPA035275",
"CAB075758"
] | [
"GOLPH6",
"GRASP55",
"GRS2"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis"
] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Enhanced | Enhanced | null | 235 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 27: Non-specific - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | 4,441 | 9 |
ENSG00000115808 | STRN | Striatin | [
"O43815"
] | 2 | 36837698-36966536 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA017286"
] | [
"PPP2R6A",
"STRN1"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [] | [
"Calmodulin-binding"
] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 85 | No | No | null | Cluster 11: White matter - Signal transduction | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,442 | 2 |
ENSG00000115816 | CEBPZ | CCAAT enhancer binding protein zeta | [
"Q03701"
] | 2 | 37201612-37231596 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052065"
] | [
"CBF2",
"CTF2"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Supported | Uncertain | null | 57 | null | null | Cluster 15: NK-cells - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 17: Non-specific - RNA processing | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 4,443 | 2 |
ENSG00000115827 | DCAF17 | DDB1 and CUL4 associated factor 17 | [
"Q5H9S7"
] | 2 | 171434217-171485052 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053339",
"HPA055040"
] | [
"C2orf37",
"FLJ13096"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Ubl conjugation pathway"
] | [] | [
"Deafness",
"Diabetes mellitus",
"Hypotrichosis",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 5 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 13: Oligodendrocytes - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Thyroid Carcinoma"
] | [
"Thyroid Carcinoma"
] | 4,445 | 4 |
ENSG00000115828 | QPCT | Glutaminyl-peptide cyclotransferase | [
"Q16769"
] | 2 | 37342827-37373322 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008406"
] | [
"GCT",
"QC"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Acyltransferase",
"Transferase"
] | [] | [
"Cytosol"
] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | Approved | Enhanced | null | 3 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in many | null | Group enriched | Detected in all | 6 | Cancer enhanced | Detected in all | null | Group enriched | Detected in many | 4 | Immune cell enriched | Detected in many | 4 | 0 | 0 | 0 | [] | [] | [] | 4,446 | 7 |
ENSG00000115839 | RAB3GAP1 | RAB3 GTPase activating protein catalytic subunit 1 | [
"Q15042"
] | 2 | 135052289-135176667 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA034494",
"HPA034495"
] | [
"KIAA0066",
"RAB3GAP",
"RAB3GAP130",
"WARBM1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [
"Cataract",
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 16 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 7: Non-specific - Transcription | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 4,447 | 3 |
ENSG00000115840 | SLC25A12 | Solute carrier family 25 member 12 | [
"O75746"
] | 2 | 171783405-171999859 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035333",
"HPA035334"
] | [
"Aralar"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Transport"
] | [] | [
"Disease variant"
] | [
"Nuclear speckles"
] | [
"Cytosol"
] | [] | [] | Uncertain | Enhanced | null | 23 | null | null | Cluster 24: Non-specific - Transcription | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 41: Striated muscle - Muscle contraction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 4,448 | 6 |
ENSG00000115841 | RMDN2 | Regulator of microtubule dynamics 2 | [
"Q96LZ7"
] | 2 | 37923187-38067142 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034705",
"HPA034706"
] | [
"FAM82A",
"FAM82A1",
"FLJ32954",
"RMD2"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Mitotic spindle",
"Cytosol"
] | [
"Golgi apparatus"
] | [] | [] | Supported | Enhanced | null | 19 | Yes | No | Cluster 2: Dendritic cells - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 47: Testis - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | 4,449 | 3 |
ENSG00000115844 | DLX2 | Distal-less homeobox 2 | [
"Q07687"
] | 2 | 172099438-172102900 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA056965"
] | [
"TES-1"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | null | null | 2 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 10: Ciliated cells - Ion channel activity | Cluster 20: Non-specific - Transcription regulation | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in single | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,450 | 4 |
ENSG00000115850 | LCT | Lactase | [
"P09848"
] | 2 | 135787850-135837184 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [] | [
"Glycosidase",
"Hydrolase",
"Multifunctional enzyme"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | null | null | null | null | null | null | null | Cluster 59: Leukemia - T-cell receptor | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 7: Small intestine - Absorption and Digestion | Tissue enriched | Detected in some | 189 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 4,451 | 9 |
ENSG00000115866 | DARS1 | Aspartyl-tRNA synthetase 1 | [
"P14868"
] | 2 | 135905881-135986100 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020451",
"HPA029804",
"HPA029805"
] | [
"DARS"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Aminoacyl-tRNA synthetase",
"Ligase"
] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 51 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 21: Non-specific - Metabolism | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,452 | 7 |
ENSG00000115875 | SRSF7 | Serine and arginine rich splicing factor 7 | [
"Q16629"
] | 2 | 38743599-38751494 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043850",
"HPA056926"
] | [
"9G8",
"AAG3",
"HSSG1",
"RBM37",
"SFRS7",
"ZCCHC20",
"ZCRB2"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing",
"mRNA transport",
"Transport"
] | [
"Repressor",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 59 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 21: Non-specific - Metabolism | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 20: Non-specific - Transcription regulation | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,453 | 9 |
ENSG00000115884 | SDC1 | Syndecan 1 | [
"P18827"
] | 2 | 20200797-20225433 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002424",
"HPA006185",
"HPA067477"
] | [
"CD138",
"SDC",
"SYND1",
"syndecan"
] | [
"Cancer-related genes",
"CD markers",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins",
"Transporters"
] | [] | [] | [
"Cancer-related genes"
] | [
"Focal adhesion sites"
] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | Approved | Enhanced | null | 18 | null | null | Cluster 17: B-cells - Immunoglobulins | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 51: Myeloma - Immunoglobulins | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 4,454 | 4 |
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