ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000049449 | RCN1 | Reticulocalbin 1 | [
"Q15293"
] | 11 | 32091074-32105722 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038474",
"HPA062104"
] | [
"FLJ37041",
"PIG20",
"Rcal",
"RCN"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Supported | Approved | null | 41 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 21: Non-specific - Metabolism | Cluster 44: Connective tissue cells - ECM organization | Cluster 10: Epididymal principal cells - Sperm maturation microenvironment | Cluster 50: Epididymis - Male reproductive secretion | Tissue enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 657 | 2 |
ENSG00000049540 | ELN | Elastin | [
"P15502"
] | 7 | 74027789-74069907 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010750",
"HPA018111",
"HPA056941"
] | [
"SVAS",
"WBS",
"WS"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [
"Williams-Beuren syndrome"
] | [
"Plasma membrane"
] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | Approved | Supported | null | 5 | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enriched | Detected in many | 6 | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Thyroid Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Thyroid Carcinoma"
] | 658 | 2 |
ENSG00000049541 | RFC2 | Replication factor C subunit 2 | [
"P35250"
] | 7 | 74231499-74254458 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029493"
] | [
"A1",
"RFC40"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA replication"
] | [] | [
"Williams-Beuren syndrome"
] | [
"Nucleoplasm"
] | [
"Golgi apparatus"
] | [] | [] | Supported | Approved | null | 39 | null | Yes | Cluster 42: Non-specific - Vesicular transport | Cluster 55: Non-specific - Transcription | Cluster 39: Non-specific - Transcription | Cluster 27: Non-specific - Cell proliferation | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 659 | 3 |
ENSG00000049618 | ARID1B | AT-rich interaction domain 1B | [
"Q8NFD5"
] | 6 | 156776020-157210779 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA016511",
"HPA075291"
] | [
"6A3-5",
"BAF250b",
"DAN15",
"ELD/OSA1",
"KIAA1235",
"p250R",
"SMARCF2"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"DNA-binding"
] | [
"Cancer-related genes",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | Supported | Approved | null | 65 | null | null | Cluster 24: Non-specific - Transcription | Cluster 15: Non-specific - Transcription | Cluster 28: Non-specific - Nuclear processes | Cluster 7: Non-specific - Transcription | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 660 | 9 |
ENSG00000049656 | CLPTM1L | CLPTM1 like | [
"Q96KA5"
] | 5 | 1317752-1345099 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014791"
] | [
"CRR9",
"FLJ14400"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Apoptosis",
"Lipid transport",
"Transport"
] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Approved | null | 6 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 29: Non-specific - Unknown function | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 661 | 4 |
ENSG00000049768 | FOXP3 | Forkhead box P3 | [
"Q9BZS1"
] | X | 49250438-49264800 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB026301",
"HPA045943",
"HPA069372"
] | [
"AIID",
"DIETER",
"IPEX",
"JM2",
"PIDX",
"SCURFIN",
"XPID"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [
"Diabetes mellitus",
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 34 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 15: Non-specific - Transcription | Cluster 59: Leukemia - T-cell receptor | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in some | 11 | 5 | 0 | 5 | [
"Bladder Urothelial Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 663 | 8 |
ENSG00000049769 | PPP1R3F | Protein phosphatase 1 regulatory subunit 3F | [
"Q6ZSY5"
] | X | 49269793-49301461 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000244",
"HPA000918",
"HPA075936"
] | [
"Hb2E"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 34: Non-specific - Mixed function | Cluster 50: Lymphoma - Unknown function | Cluster 30: Epididymal principal cells - Sperm storage microenvironment | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 5 | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 664 | 7 |
ENSG00000049883 | PTCD2 | Pentatricopeptide repeat domain 2 | [
"Q8WV60"
] | 5 | 72320367-72368395 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043686"
] | [
"FLJ12598"
] | [
"Predicted intracellular proteins"
] | [
"mRNA processing"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 6 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 21: Non-specific - Metabolism | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 666 | 4 |
ENSG00000050030 | NEXMIF | Neurite extension and migration factor | [
"Q5QGS0"
] | X | 74732856-74925472 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000407"
] | [
"KIAA2022",
"KIDLIA",
"MRX98",
"XPN"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Midbody",
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 1 | Yes | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 11: Neuronal - Sensory perception | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 667 | 7 |
ENSG00000050130 | JKAMP | JNK1/MAPK8 associated membrane protein | [
"Q9P055"
] | 14 | 59484443-59505410 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031172",
"HPA071650"
] | [
"C14orf100",
"CDA06",
"HSPC213",
"HSPC327",
"JAMP"
] | [
"Cancer-related genes",
"Predicted membrane proteins"
] | [
"Unfolded protein response"
] | [] | [
"Cancer-related genes"
] | [
"Vesicles"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Supported | null | 3 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 50: Non-specific - Nucleic acid binding | Cluster 30: Non-specific - Gene expression regulation | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 668 | 9 |
ENSG00000050344 | NFE2L3 | NFE2 like bZIP transcription factor 3 | [
"Q9Y4A8"
] | 7 | 26152198-26187137 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055889"
] | [
"Nrf3"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Vesicles"
] | [] | [
"Intracellular and membrane"
] | [
"Transcription"
] | Approved | Enhanced | null | 10 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 35: Non-specific - DNA binding | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 20: Non-specific - Transcription regulation | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Rectum Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 671 | 5 |
ENSG00000050393 | MCUR1 | Mitochondrial calcium uniporter regulator 1 | [
"Q96AQ8"
] | 6 | 13786557-13814568 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA078654"
] | [
"C6orf79",
"CCDC90A",
"FLJ20958"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 7 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 1: Neurons - Mixed function | Cluster 28: Non-specific - Nuclear processes | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 672 | 8 |
ENSG00000050405 | LIMA1 | LIM domain and actin binding 1 | [
"Q9UHB6"
] | 12 | 50175788-50283520 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023871",
"HPA052645"
] | [
"EPLIN"
] | [
"Predicted intracellular proteins"
] | [
"Cholesterol metabolism",
"Lipid metabolism",
"Steroid metabolism",
"Sterol metabolism"
] | [
"Actin-binding"
] | [] | [
"Plasma membrane",
"Actin filaments"
] | [
"Focal adhesion sites",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 50 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 25: Non-specific - Transcription | Cluster 72: Neuronal - Signal transduction | Cluster 89: Adipocytes - Lipid metabolism | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 673 | 2 |
ENSG00000050426 | LETMD1 | LETM1 domain containing 1 | [
"Q6P1Q0"
] | 12 | 51047962-51060424 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA074361"
] | [
"HCCR",
"HCCR-1",
"HCCR-2",
"HCCR1",
"HCCR2",
"SLC55A3"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Proto-oncogene"
] | [
"Mitochondria"
] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | Supported | null | null | 12 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 23: Choroid plexus - Mixed function | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 674 | 5 |
ENSG00000050438 | SLC4A8 | Solute carrier family 4 member 8 | [
"Q2Y0W8"
] | 12 | 51391317-51515763 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA077895"
] | [
"NBC3"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Anion exchange",
"Antiport",
"Ion transport",
"Sodium transport",
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [] | [] | [] | Approved | null | null | 1 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in many | 4 | Cancer enriched | Detected in many | 6 | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 675 | 8 |
ENSG00000050555 | LAMC3 | Laminin subunit gamma 3 | [
"Q9Y6N6"
] | 9 | 131009174-131094473 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022814"
] | [
"DKFZp434E202"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [
"Disease variant"
] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Cell adhesion"
] | null | Enhanced | null | 5 | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 3: Rhabdoid - Membrane components | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Liver Hepatocellular Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 676 | 8 |
ENSG00000050628 | PTGER3 | Prostaglandin E receptor 3 | [
"P43115"
] | 1 | 70852353-71047816 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA010689"
] | [
"EP3",
"lnc003875"
] | [
"FDA approved drug targets",
"G-protein coupled receptors",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Uncertain | null | 3 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 23: Choroid plexus - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in some | 6 | Cancer enriched | Detected in many | 7 | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 62 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 677 | 8 |
ENSG00000050730 | TNIP3 | TNFAIP3 interacting protein 3 | [
"Q96KP6"
] | 4 | 121131408-121227466 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043063"
] | [
"ABIN-3",
"FLJ21162",
"LIND"
] | [
"Predicted intracellular proteins"
] | [
"Inflammatory response"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Nuclear bodies",
"Plasma membrane"
] | [] | [] | Approved | Uncertain | null | 31 | null | null | Cluster 1: T-cells - Unknown function | Cluster 49: Hindbrain - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 678 | 8 |
ENSG00000050767 | COL23A1 | Collagen type XXIII alpha 1 chain | [
"Q86Y22"
] | 5 | 178237476-178590393 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA067824"
] | [
"DKFZp434K0621"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 1 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 33: Thyroid gland - Tissue development | Tissue enriched | Detected in some | 6 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 680 | 4 |
ENSG00000050820 | BCAR1 | BCAR1 scaffold protein, Cas family member | [
"P56945"
] | 16 | 75228181-75268053 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000443",
"HPA042282",
"HPA063796"
] | [
"CAS",
"CASS1",
"Crkas",
"P130Cas"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell adhesion"
] | [] | [
"Diabetes mellitus"
] | [
"Plasma membrane",
"Focal adhesion sites"
] | [
"Nucleoli",
"Nucleoli fibrillar center",
"Cytosol"
] | [] | [] | Supported | Approved | Approved | 98 | null | null | null | Cluster 34: Non-specific - Mixed function | Cluster 68: Non-specific - Cell cycle regulation | Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 681 | 7 |
ENSG00000051009 | FHIP1B | FHF complex subunit HOOK interacting protein 1B | [
"Q8N612"
] | 11 | 6211345-6234711 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA055994",
"HPA063987"
] | [
"C11orf56",
"DKFZP566M1046",
"FAM160A2",
"FHIP",
"FLJ22665",
"KIAA1759"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | 12 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 682 | 5 |
ENSG00000051108 | HERPUD1 | Homocysteine inducible ER protein with ubiquitin like domain 1 | [
"Q15011"
] | 16 | 56932142-56944864 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB037041",
"CAB037104",
"HPA040754",
"HPA041219"
] | [
"HERP",
"KIAA0025",
"Mif1",
"SUP"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Unfolded protein response"
] | [] | [
"Cancer-related genes"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Uncertain | Approved | null | 15 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 50: Non-specific - Nucleic acid binding | Cluster 13: Non-specific - Mixed function | Cluster 78: Plasma cells - Antibody production & ER-stress response | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 683 | 3 |
ENSG00000051128 | HOMER3 | Homer scaffold protein 3 | [
"Q9NSC5"
] | 19 | 18929201-18941261 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB032656",
"HPA040999",
"CAB079015"
] | [
"HOMER-3"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Plasma membrane",
"Cytoplasmic bodies"
] | [] | [] | Supported | Enhanced | Supported | 85 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 25: Non-specific - Transcription | Cluster 51: Myeloma - Immunoglobulins | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 684 | 3 |
ENSG00000051180 | RAD51 | RAD51 recombinase | [
"Q06609"
] | 15 | 40694774-40732340 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010381",
"HPA039310"
] | [
"BRCC5",
"FANCR",
"HsRad51",
"HsT16930",
"RAD51A",
"RECA"
] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA recombination",
"DNA repair"
] | [
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant",
"Fanconi anemia"
] | [
"Nucleoli"
] | [
"Mitochondria",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 107 | null | Yes | Cluster 16: Non-specific - Cell proliferation | Cluster 48: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 7 | 8 | 3 | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 685 | 1 |
ENSG00000051341 | POLQ | DNA polymerase theta | [
"O75417"
] | 3 | 121431431-121545988 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053359"
] | [
"POLH"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"DNA-directed DNA polymerase",
"Helicase",
"Hydrolase",
"Multifunctional enzyme",
"Nucleotidyltransferase",
"Transferase"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Golgi apparatus",
"Cytosol"
] | [] | [] | Supported | null | null | 4 | null | Yes | null | Cluster 37: Neurons - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 686 | 7 |
ENSG00000051382 | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | [
"P42338"
] | 3 | 138652698-138834928 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB031938",
"HPA042288",
"HPA064207"
] | [
"PIK3C1"
] | [
"Cancer-related genes",
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Autophagy",
"Cell adhesion",
"Endocytosis",
"Lipid metabolism"
] | [
"Kinase",
"Transferase"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Nucleoli"
] | [
"Vesicles",
"Midbody"
] | [] | [] | Supported | Approved | null | 23 | Yes | No | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 31: Non-specific - Transcription | Cluster 49: HMC-1 - Innate immune response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 687 | 1 |
ENSG00000051523 | CYBA | Cytochrome b-245 alpha chain | [
"P13498"
] | 16 | 88643275-88651083 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009492",
"HPA072667"
] | [
"p22-PHOX"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Electron transport",
"Transport"
] | [
"Oxidoreductase"
] | [
"Chronic granulomatous disease",
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 30 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 35: RS4;11 - Unknown function | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 4 | 0 | 4 | [
"Colon Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 688 | 8 |
ENSG00000051596 | THOC3 | THO complex subunit 3 | [
"Q96J01"
] | 5 | 175917873-176034680 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042764",
"HPA044009",
"HPA045071"
] | [
"MGC5469",
"TEX1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing",
"mRNA transport",
"Transport"
] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Supported | Approved | null | 47 | No | No | Cluster 43: Non-specific - Transcription & Translation | Cluster 29: Forebrain - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 105: Non-specific - Mixed function | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 689 | 7 |
ENSG00000051620 | HEBP2 | Heme binding protein 2 | [
"Q9Y5Z4"
] | 6 | 138403531-138422197 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA016928"
] | [
"C6orf34",
"SOUL"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 5 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 38: Sub-cortical - Mixed function | Cluster 28: Non-specific - Nuclear processes | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 690 | 2 |
ENSG00000052126 | PLEKHA5 | Pleckstrin homology domain containing A5 | [
"Q9HAU0"
] | 12 | 19129669-19376400 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035923",
"HPA035924",
"HPA041455"
] | [
"FLJ10667",
"KIAA1686",
"PEPP2"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 32 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enriched | Detected in many | 5 | 0 | 0 | 0 | [] | [] | [] | 692 | 6 |
ENSG00000052344 | PRSS8 | Serine protease 8 | [
"Q16651"
] | 16 | 31131433-31135727 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030436"
] | [
"CAP1"
] | [
"Enzymes",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [] | [] | [] | [
"Secreted - unknown location"
] | [
"Enzyme"
] | null | Uncertain | null | 32 | null | null | null | Cluster 5: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func. | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 693 | 4 |
ENSG00000052723 | SIKE1 | Suppressor of IKBKE 1 | [
"Q9BRV8"
] | 1 | 114769479-114780685 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024177",
"HPA025726"
] | [
"FLJ21168",
"SIKE"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Focal adhesion sites"
] | [
"Vesicles"
] | [] | [] | Approved | Supported | null | 33 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 26: Oligodendrocytes - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Thyroid Carcinoma"
] | [
"Thyroid Carcinoma"
] | 694 | 2 |
ENSG00000052749 | RRP12 | Ribosomal RNA processing 12 homolog | [
"Q5JTH9"
] | 10 | 97356358-97426076 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049945",
"HPA074403"
] | [
"KIAA0690"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoli"
] | [
"Vesicles",
"Plasma membrane",
"Cytosol"
] | [] | [] | Supported | null | null | 43 | No | No | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 52: Non-specific - Mitochondria | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Group enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 695 | 1 |
ENSG00000052795 | FNIP2 | Folliculin interacting protein 2 | [
"Q9P278"
] | 4 | 158769026-158908050 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042779",
"HPA052758",
"HPA072420"
] | [
"FNIPL",
"KIAA1450",
"MAPO1"
] | [
"Predicted intracellular proteins"
] | [
"DNA damage"
] | [] | [] | [
"Cytosol"
] | [
"Centriolar satellite"
] | [] | [] | Supported | Approved | null | 4 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 11: White matter - Signal transduction | Cluster 21: Lymphoma - Adaptive immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in all | null | Group enriched | Detected in some | 5 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 696 | 3 |
ENSG00000052802 | MSMO1 | Methylsterol monooxygenase 1 | [
"Q15800"
] | 4 | 165327667-165343164 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055073",
"HPA056127"
] | [
"DESP4",
"ERG25",
"SC4MOL"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Cholesterol biosynthesis",
"Cholesterol metabolism",
"Lipid biosynthesis",
"Lipid metabolism",
"Steroid biosynthesis",
"Steroid metabolism",
"Sterol biosynthesis",
"Sterol metabolism"
] | [
"Oxidoreductase"
] | [
"Cataract",
"Disease variant"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Enhanced | null | 48 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 49: Hindbrain - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 697 | 2 |
ENSG00000052841 | TTC17 | Tetratricopeptide repeat domain 17 | [
"Q96AE7"
] | 11 | 43358920-43494933 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038508"
] | [
"FLJ10890"
] | [
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [] | [
"Plasma membrane"
] | [
"Cytosol"
] | [
"Intracellular and membrane"
] | [
"Other"
] | Supported | Approved | null | 31 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 6: Non-specific - Immune response | Cluster 51: Myeloma - Immunoglobulins | Cluster 7: Non-specific - Transcription | Cluster 60: Stomach - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 698 | 1 |
ENSG00000052850 | ALX4 | ALX homeobox 4 | [
"Q9H161"
] | 11 | 44260440-44310139 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001903"
] | [
"FPP",
"KIAA1788",
"PFM",
"PFM2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [
"Craniosynostosis",
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 2 | null | null | null | Cluster 17: Choroid plexus - Cilium | Cluster 65: Non-specific - Unknown function | Cluster 108: Fibroblasts - ECM organization | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in many | 4 | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 699 | 5 |
ENSG00000053108 | FSTL4 | Follistatin like 4 | [
"Q6MZW2"
] | 5 | 133196455-133612541 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA045920",
"HPA070859"
] | [
"KIAA1061"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | Approved | Uncertain | null | null | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling | Cluster 10: Brain - Synaptic signal transduction | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 700 | 9 |
ENSG00000053254 | FOXN3 | Forkhead box N3 | [
"O00409"
] | 14 | 89124871-89619149 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA006180",
"HPA059209"
] | [
"C14orf116",
"CHES1"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Cell cycle",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 25: Non-specific - Transcription | Cluster 54: Non-specific - Transcription | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 701 | 3 |
ENSG00000053372 | MRTO4 | MRT4 homolog, ribosome maturation factor | [
"Q9UKD2"
] | 1 | 19251805-19260128 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026446"
] | [
"C1orf33",
"dJ657E11.4",
"MRT4"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [
"Ribosome biogenesis"
] | [] | [] | [
"Nucleoplasm",
"Nuclear membrane"
] | [
"Nucleoli"
] | [] | [] | Approved | Approved | null | 19 | Yes | No | Cluster 30: Non-specific - DNA binding | Cluster 14: Neurons - Synaptic function | Cluster 37: Non-specific - mRNA processing | Cluster 17: Non-specific - RNA processing | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 704 | 4 |
ENSG00000053438 | NNAT | Neuronatin | [
"Q16517"
] | 20 | 37521206-37523690 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [] | [
"Peg5"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Developmental protein"
] | [] | [] | [] | [] | [] | null | null | null | 1 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 11: Neuronal - Sensory perception | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 78: Brain - Neuronal signaling | Group enriched | Detected in many | 12 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 11 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 705 | 2 |
ENSG00000053501 | USE1 | Unconventional SNARE in the ER 1 | [
"Q9NZ43"
] | 19 | 17215346-17219829 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026851",
"HPA047562"
] | [
"D12",
"MDS032",
"p31",
"SLT1"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 63 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 11: White matter - Signal transduction | Cluster 23: Non-specific - Transcription | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 706 | 2 |
ENSG00000053524 | MCF2L2 | MCF.2 cell line derived transforming sequence-like 2 | [
"Q86YR7"
] | 3 | 183178041-183428778 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA038946",
"HPA038947",
"HPA061485"
] | [
"ARHGEF22",
"KIAA0861"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [
"Diabetes mellitus"
] | [
"Centriolar satellite",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 5 | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 707 | 8 |
ENSG00000053702 | NRIP2 | Nuclear receptor interacting protein 2 | [
"Q9BQI9"
] | 12 | 2825348-2835544 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039197",
"HPA039860"
] | [
"DKFZP761G1913"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Nuclear bodies"
] | [] | [] | Approved | Enhanced | null | 2 | Yes | No | Cluster 16: Non-specific - Cell proliferation | Cluster 26: Oligodendrocytes - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 71: Cerebellum - Nervous system development | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 4 | 3 | 2 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 708 | 6 |
ENSG00000053747 | LAMA3 | Laminin subunit alpha 3 | [
"Q16787"
] | 18 | 23689453-23956222 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA009309",
"CAB010757"
] | [
"BM600-150kDa",
"epiligrin",
"kalinin-165kDa",
"LAMNA",
"nicein-150kDa"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [
"Disease variant",
"Epidermolysis bullosa"
] | [
"Endoplasmic reticulum"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Cell adhesion"
] | Approved | Uncertain | null | 2 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 709 | 5 |
ENSG00000053770 | AP5M1 | Adaptor related protein complex 5 subunit mu 1 | [
"Q9H0R1"
] | 14 | 57268924-57298742 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA055768",
"HPA057098"
] | [
"C14orf108",
"FLJ10813",
"mu5",
"MuD",
"MUDENG"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 50: Non-specific - Nucleic acid binding | Cluster 30: Non-specific - Gene expression regulation | Cluster 97: Non-specific - Cellular respiration | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Rectum Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 710 | 1 |
ENSG00000053900 | ANAPC4 | Anaphase promoting complex subunit 4 | [
"Q9UJX5"
] | 4 | 25377263-25418498 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB032519",
"HPA038395",
"HPA038396"
] | [
"APC4"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis",
"Ubl conjugation pathway"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 91 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 53: Neurons - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Breast Invasive Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 711 | 5 |
ENSG00000053918 | KCNQ1 | Potassium voltage-gated channel subfamily Q member 1 | [
"P51787"
] | 11 | 2444684-2849105 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011306",
"HPA048553",
"HPA071107"
] | [
"JLNS1",
"KCNA8",
"KCNA9",
"Kv7.1",
"KVLQT1",
"LQT",
"LQT1"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Calmodulin-binding",
"Ion channel",
"Potassium channel",
"Voltage-gated channel"
] | [
"Atrial fibrillation",
"Deafness",
"Diabetes mellitus",
"Disease variant",
"FDA approved drug targets",
"Long QT syndrome",
"Short QT syndrome"
] | [
"Endoplasmic reticulum"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | Enhanced | Enhanced | null | 9 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 712 | 2 |
ENSG00000054116 | TRAPPC3 | Trafficking protein particle complex subunit 3 | [
"O43617"
] | 1 | 36136570-36156053 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA028408"
] | [
"BET3"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"ER-Golgi transport",
"Transport"
] | [] | [] | [
"Golgi apparatus",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 41 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 21: Non-specific - Metabolism | Cluster 37: Non-specific - mRNA processing | Cluster 8: Non-specific - Secretory pathway | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 713 | 4 |
ENSG00000054118 | THRAP3 | Thyroid hormone receptor associated protein 3 | [
"Q9Y2W1"
] | 1 | 36224432-36305357 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012041",
"CAB017472",
"HPA063765"
] | [
"BCLAF2",
"TRAP150"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"mRNA processing",
"mRNA splicing",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Receptor"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Enhanced | Supported | null | 95 | null | null | Cluster 41: Basophils - Unknown function | Cluster 50: Non-specific - Nucleic acid binding | Cluster 37: Non-specific - mRNA processing | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 714 | 9 |
ENSG00000054148 | PHPT1 | Phosphohistidine phosphatase 1 | [
"Q9NRX4"
] | 9 | 136848724-136851027 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013584",
"HPA020952"
] | [
"bA216L13.10",
"CGI-202",
"DKFZp564M173",
"HSPC141",
"PHP14"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm",
"Nuclear bodies",
"Plasma membrane"
] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 27: Non-specific - Mixed function | Cluster 43: Non-specific - Basic cellular processes | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 715 | 9 |
ENSG00000054277 | OPN3 | Opsin 3 | [
"Q9H1Y3"
] | 1 | 241590102-241677376 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013682",
"HPA049243"
] | [
"ECPN",
"encephalopsin",
"ERO",
"NMO-1",
"PPP1R116"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [
"Sensory transduction"
] | [
"G-protein coupled receptor",
"Photoreceptor protein",
"Receptor",
"Retinal protein",
"Transducer"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Plasma membrane",
"Primary cilium",
"Basal body"
] | [] | [] | Approved | Uncertain | null | 1 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 53: Neurons - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 4 | 4 | 0 | 4 | [] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 719 | 2 |
ENSG00000054282 | SDCCAG8 | SHH signaling and ciliogenesis regulator SDCCAG8 | [
"Q86SQ7"
] | 1 | 243256034-243500091 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA025737",
"HPA044477",
"HPA072495"
] | [
"BBS16",
"CCCAP",
"NPHP10",
"NY-CO-8",
"SLSN7"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [
"Bardet-Biedl syndrome",
"Ciliopathy",
"Leber congenital amaurosis",
"Nephronophthisis",
"Obesity",
"Senior-Loken syndrome"
] | [
"Centrosome",
"Basal body"
] | [
"Primary cilium"
] | [] | [] | Supported | Approved | null | 6 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 13: Oligodendrocytes - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 720 | 8 |
ENSG00000054356 | PTPRN | Protein tyrosine phosphatase receptor type N | [
"Q16849"
] | 2 | 219289623-219309648 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007152",
"HPA007179"
] | [
"IA-2",
"ICA512"
] | [
"Disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Receptor"
] | [
"Diabetes mellitus"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Uncertain | Enhanced | null | 48 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 10: Brain - Synaptic signal transduction | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 9 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 721 | 2 |
ENSG00000054392 | HHAT | Hedgehog acyltransferase | [
"Q5VTY9"
] | 1 | 210328252-210676296 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA016462"
] | [
"FLJ10724",
"GUP2",
"MART-2",
"MART2",
"rasp",
"sit",
"ski",
"Skn"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Acyltransferase",
"Developmental protein",
"Transferase"
] | [
"Disease variant",
"Dwarfism"
] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 65: Non-specific - Unknown function | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 20: Pituitary gland - Hormone signaling | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 722 | 9 |
ENSG00000054523 | KIF1B | Kinesin family member 1B | [
"O60333"
] | 1 | 10210570-10381603 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB015177",
"HPA026447"
] | [
"CMT2",
"CMT2A",
"HMSNII",
"KIAA0591",
"KLP"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [
"Isomerase",
"Motor protein"
] | [
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Microtubules",
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | [] | Uncertain | Approved | null | 28 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 26: Oligodendrocytes - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 723 | 7 |
ENSG00000054598 | FOXC1 | Forkhead box C1 | [
"Q12948"
] | 6 | 1609915-1613897 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040670"
] | [
"ARA",
"FKHL7",
"FREAC3",
"IGDA",
"IHG1",
"IRID1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Angiogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding",
"Repressor"
] | [
"Deafness",
"Disease variant",
"Peters anomaly"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 27 | null | null | null | Cluster 47: Endothelial cells - Vasculature | Cluster 71: Lymphoma - Inflammatory response | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 82: Salivary gland - Secretion | Group enriched | Detected in many | 6 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | 724 | 7 |
ENSG00000054611 | TBC1D22A | TBC1 domain family member 22A | [
"Q8WUA7"
] | 22 | 46762617-47175699 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001173",
"HPA078026"
] | [
"C22orf4"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 20: Macrophages & Microglia - Immune response | Cluster 66: Non-specific - Mitochondria | Cluster 82: Dendritic cells - Antigen presentation | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 725 | 5 |
ENSG00000054654 | SYNE2 | Spectrin repeat containing nuclear envelope protein 2 | [
"Q8WXH0"
] | 14 | 63761899-64226433 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003435",
"HPA050204"
] | [
"DKFZP434H2235",
"KIAA1011",
"Nesp2",
"Nesprin-2",
"NUA",
"NUANCE",
"SYNE-2"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Actin-binding"
] | [
"Disease variant",
"Emery-Dreifuss muscular dystrophy"
] | [
"Nuclear membrane",
"Intermediate filaments"
] | [
"Primary cilium"
] | [] | [] | Approved | Enhanced | null | 23 | No | Yes | Cluster 45: Eosinophils - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 10: Ciliated cells - Ion channel activity | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 726 | 9 |
ENSG00000054690 | PLEKHH1 | Pleckstrin homology, MyTH4 and FERM domain containing H1 | [
"Q9ULM0"
] | 14 | 67533290-67589612 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA047707",
"HPA051964"
] | [
"KIAA1200"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Centrosome"
] | [] | [] | [] | Approved | Uncertain | null | 2 | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 60: Prostate cancer - Unknown function | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 727 | 4 |
ENSG00000054793 | ATP9A | ATPase phospholipid transporting 9A (putative) | [
"O75110"
] | 20 | 51596514-51768390 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB020699",
"HPA035630"
] | [
"ATPIIA",
"KIAA0611"
] | [
"Enzymes",
"Predicted membrane proteins",
"Transporters"
] | [
"Lipid transport",
"Transport"
] | [
"Translocase"
] | [
"Disease variant",
"Intellectual disability"
] | [] | [] | [] | [] | null | Enhanced | null | 9 | null | null | Cluster 15: NK-cells - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 40: Non-specific - Unknown function | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 4 | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 728 | 3 |
ENSG00000054796 | SPO11 | SPO11 initiator of meiotic double stranded breaks | [
"Q9Y5K1"
] | 20 | 57329803-57343994 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CT35",
"SPATA43",
"TOPOVIA",
"TOPVIA"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Meiosis"
] | [
"DNA-binding",
"Isomerase",
"Topoisomerase"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | null | Cluster 70: DU4475 - Unknown function | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in single | 79 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 9 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 729 | 5 |
ENSG00000054803 | CBLN4 | Cerebellin 4 precursor | [
"Q9NTU7"
] | 20 | 55997357-56005519 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA056335",
"HPA074497"
] | [
"CBLNL1",
"dJ885A10.1"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Cytosol",
"Flagellar centriole",
"Mid piece",
"Principal piece"
] | [
"Perinuclear theca",
"Calyx"
] | [
"Secreted in brain"
] | [
"No annotated function"
] | Approved | null | Supported | 60 | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 11: Neuronal - Sensory perception | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 730 | 9 |
ENSG00000054938 | CHRDL2 | Chordin like 2 | [
"Q6WN34"
] | 11 | 74696429-74731426 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021771",
"HPA076522"
] | [
"BNF1"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Chondrogenesis",
"Differentiation",
"Osteogenesis"
] | [
"Developmental protein"
] | [] | [
"Vesicles"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Developmental protein"
] | Approved | Uncertain | null | null | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 4: Breast lactating luminal cells - Lactation | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in some | 21 | Not detected in immune cells | Not detected | null | 4 | 2 | 3 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 731 | 8 |
ENSG00000054965 | FAM168A | Family with sequence similarity 168 member A | [
"Q92567"
] | 11 | 73400487-73598189 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037580"
] | [
"KIAA0280",
"TCRP1"
] | [
"Disease related genes",
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Enhanced | null | 23 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 19: Astrocytes - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 732 | 5 |
ENSG00000054967 | RELT | RELT TNF receptor | [
"Q969Z4"
] | 11 | 73376399-73397474 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042269"
] | [
"FLJ14993",
"TNFRSF19L"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis"
] | [
"Receptor"
] | [
"Amelogenesis imperfecta",
"Disease variant"
] | [
"Cytosol"
] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | Supported | null | null | 17 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 11: White matter - Signal transduction | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in many | 6 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 733 | 7 |
ENSG00000055044 | NOP58 | NOP58 ribonucleoprotein | [
"Q9Y2X3"
] | 2 | 202265736-202303661 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018472",
"HPA021062"
] | [
"HSPC120",
"NOP5"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis"
] | [
"Ribonucleoprotein"
] | [] | [
"Nucleoli fibrillar center"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | Supported | null | 80 | null | Yes | Cluster 9: T-regs - Cell cycle regulation | Cluster 31: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 735 | 3 |
ENSG00000055070 | SZRD1 | SUZ RNA binding domain containing 1 | [
"Q7Z422"
] | 1 | 16352575-16398145 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA024221"
] | [
"C1orf144",
"DKFZp566C0424"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 2 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 19: Astrocytes - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 736 | 5 |
ENSG00000055118 | KCNH2 | Potassium voltage-gated channel subfamily H member 2 | [
"Q12809"
] | 7 | 150944961-150978321 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"erg1",
"HERG",
"Kv11.1",
"LQT2"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Ion channel",
"Potassium channel",
"Voltage-gated channel"
] | [
"Deafness",
"Disease variant",
"FDA approved drug targets",
"Long QT syndrome",
"Short QT syndrome"
] | [] | [] | [] | [] | null | null | null | 11 | null | null | null | Cluster 49: Hindbrain - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 67: Testis - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 737 | 8 |
ENSG00000055147 | FAM114A2 | Family with sequence similarity 114 member A2 | [
"Q9NRY5"
] | 5 | 153990148-154038936 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035869",
"HPA035870"
] | [
"133K02",
"C5orf3"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 12 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 739 | 7 |
ENSG00000055163 | CYFIP2 | Cytoplasmic FMR1 interacting protein 2 | [
"Q96F07"
] | 5 | 157266079-157395595 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB055519",
"HPA068106",
"HPA071459"
] | [
"PIR121"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Cell adhesion"
] | [] | [
"Disease variant",
"Epilepsy"
] | [
"Endoplasmic reticulum"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 33 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 38: Sub-cortical - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 740 | 7 |
ENSG00000055332 | EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2 | [
"P19525"
] | 2 | 37099210-37157522 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB003845",
"HPA019795",
"HPA063893"
] | [
"PKR",
"PPP1R83",
"PRKR"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"Host-virus interaction",
"Immunity",
"Innate immunity",
"Transcription",
"Transcription regulation"
] | [
"Kinase",
"RNA-binding",
"Serine/threonine-protein kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Disease variant",
"Dystonia"
] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 115 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 31: Non-specific - Antiviral immune response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 15: Bone marrow - Innate immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Pancreatic Adenocarcinoma"
] | 743 | 9 |
ENSG00000055483 | USP36 | Ubiquitin specific peptidase 36 | [
"Q9P275"
] | 17 | 78787381-78841441 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012082",
"HPA012395",
"HPA052860"
] | [
"FLJ12851",
"KIAA1453"
] | [
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"RNA-binding",
"Thiol protease",
"Transferase"
] | [] | [
"Nucleoli",
"Nucleoli rim"
] | [
"Nuclear speckles"
] | [] | [] | Enhanced | Uncertain | Supported | 54 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 27: Breast cancer - Unknown function | Cluster 103: Non-specific - Basic cellular processes | Cluster 15: Bone marrow - Innate immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 744 | 8 |
ENSG00000055609 | KMT2C | Lysine methyltransferase 2C | [
"Q8NEZ4"
] | 7 | 152134922-152436644 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA062814",
"HPA074736"
] | [
"HALR",
"KIAA1506",
"MLL3"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Acyltransferase",
"Chromatin regulator",
"DNA-binding",
"Methyltransferase",
"Transferase"
] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | null | null | 34 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 6: Non-specific - Immune response | Cluster 39: Non-specific - Transcription | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 745 | 5 |
ENSG00000055732 | MCOLN3 | Mucolipin TRP cation channel 3 | [
"Q8TDD5"
] | 1 | 85018082-85048500 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018106",
"HPA062137"
] | [
"FLJ11006",
"TRP-ML3",
"TRPML3"
] | [
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 2 | null | null | null | Cluster 29: Forebrain - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 4: Adrenal gland - Steroid metabolism | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 746 | 2 |
ENSG00000055813 | CCDC85A | Coiled-coil domain containing 85A | [
"Q96PX6"
] | 2 | 56183990-56386172 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043106",
"HPA057020"
] | [
"KIAA1912"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 4 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 46: Lymphoma - Humoral immune response | Cluster 109: Neurons - Neuronal signaling | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 747 | 2 |
ENSG00000055917 | PUM2 | Pumilio RNA binding family member 2 | [
"Q8TB72"
] | 2 | 20248691-20352234 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030316",
"HPA049670"
] | [
"KIAA0235",
"PUMH2"
] | [
"Predicted intracellular proteins"
] | [
"Translation regulation"
] | [
"RNA-binding"
] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 10 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 31: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 748 | 5 |
ENSG00000055950 | MRPL43 | Mitochondrial ribosomal protein L43 | [
"Q8N983"
] | 10 | 100969458-100987515 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA073022"
] | [
"bMRP36a"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [
"Nucleoplasm",
"Mitochondria"
] | [] | [] | [] | Approved | null | null | 13 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 749 | 7 |
ENSG00000055957 | ITIH1 | Inter-alpha-trypsin inhibitor heavy chain 1 | [
"P19827"
] | 3 | 52777595-52792068 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041639",
"HPA042049"
] | [
"H1P",
"IATIH",
"ITIH"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Protease inhibitor",
"Serine protease inhibitor"
] | [] | [
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Enzyme inhibitor"
] | Approved | Approved | null | 4 | null | null | null | null | Cluster 18: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 642 | Not detected | Not detected | null | Cancer enriched | Detected in some | 457 | Cell type enriched | Detected in some | 65 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 751 | 3 |
ENSG00000056050 | HPF1 | Histone PARylation factor 1 | [
"Q9NWY4"
] | 4 | 169729470-169757944 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043467"
] | [
"C4orf27",
"FLJ20534"
] | [
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [] | [] | [
"Cytosol"
] | [
"Microtubules",
"Cytokinetic bridge"
] | [] | [] | Approved | Uncertain | Approved | 7 | Yes | No | Cluster 3: Non-specific - Nuclear processes | Cluster 28: Oligodendrocytes - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 97: Non-specific - Cellular respiration | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 752 | 6 |
ENSG00000056097 | ZFR | Zinc finger RNA binding protein | [
"Q96KR1"
] | 5 | 32354350-32444740 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA016666"
] | [
"SPG71",
"ZFR1"
] | [
"Predicted intracellular proteins"
] | [] | [
"Developmental protein",
"DNA-binding",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Supported | null | 78 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 34: Non-specific - Mixed function | Cluster 29: Non-specific - Unknown function | Cluster 17: Non-specific - RNA processing | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 753 | 7 |
ENSG00000056277 | ZNF280C | Zinc finger protein 280C | [
"Q8ND82"
] | X | 130202707-130268899 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051494",
"HPA055788"
] | [
"FLJ20095",
"SUHW3",
"ZNF633",
"ZPET"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Nucleoli fibrillar center"
] | [] | [] | [] | Approved | Enhanced | null | 21 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 31: Non-specific - Transcription | Cluster 36: Non-specific - mRNA processing | Cluster 20: Non-specific - Transcription regulation | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Thyroid Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Thyroid Carcinoma"
] | 754 | 6 |
ENSG00000056291 | NPFFR2 | Neuropeptide FF receptor 2 | [
"Q9Y5X5"
] | 4 | 72031902-72148305 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026825"
] | [
"GPR74",
"NPFF2",
"NPGPR"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [
"Plasma membrane"
] | [
"Actin filaments"
] | [] | [] | Approved | null | null | null | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 3: Rhabdoid - Membrane components | Cluster 4: Breast lactating luminal cells - Lactation | Cluster 80: Thymus - Adaptive immune response | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in some | null | Cell type enriched | Detected in some | 9 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 755 | 7 |
ENSG00000056487 | PHF21B | PHD finger protein 21B | [
"Q96EK2"
] | 22 | 44881162-45010005 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053834",
"HPA074665"
] | [
"BHC80L",
"FLJ34161",
"PHF4"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Nucleoli fibrillar center"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 3 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 21: Testis - Mixed function | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 6 | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 756 | 9 |
ENSG00000056558 | TRAF1 | TNF receptor associated factor 1 | [
"Q13077"
] | 9 | 120902393-120929173 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001852",
"CAB009593"
] | [
"EBI6"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Enhanced | null | 240 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 11: White matter - Signal transduction | Cluster 55: Lymphoma - Immune response | Cluster 82: Dendritic cells - Antigen presentation | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 3 | 0 | 4 | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 757 | 3 |
ENSG00000056586 | RC3H2 | Ring finger and CCCH-type domains 2 | [
"Q9HBD1"
] | 9 | 122844556-122905359 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042863",
"HPA062144"
] | [
"FLJ20301",
"FLJ20713",
"MNAB",
"RNF164"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Ubl conjugation pathway"
] | [
"Repressor",
"RNA-binding",
"Transferase"
] | [] | [
"Vesicles"
] | [] | [] | [] | Enhanced | Approved | null | 67 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 31: Non-specific - Transcription | Cluster 43: Non-specific - Basic cellular processes | Cluster 7: Non-specific - Transcription | Cluster 40: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Lung Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 758 | 5 |
ENSG00000056736 | IL17RB | Interleukin 17 receptor B | [
"Q9NRM6"
] | 3 | 53846568-53865794 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005482"
] | [
"CRL4",
"EVI27",
"IL17BR",
"IL17RH1"
] | [
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [] | [
"Vesicles",
"Plasma membrane"
] | [] | [
"Intracellular and membrane"
] | [
"Receptor"
] | Approved | Enhanced | null | 2 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 18: Liver cancer - Metabolism | Cluster 95: Tuft cells - Chemosensory signaling | Cluster 76: Non-specific - Metabolism | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 9 | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 759 | 8 |
ENSG00000056972 | TRAF3IP2 | TRAF3 interacting protein 2 | [
"O43734"
] | 6 | 111555381-111606906 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036352"
] | [
"ACT1",
"C6orf2",
"C6orf4",
"C6orf5",
"C6orf6",
"CIKS",
"DKFZP586G0522"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Inflammatory response",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Disease variant"
] | [
"Golgi apparatus"
] | [
"Vesicles"
] | [] | [] | Approved | Approved | null | 19 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 35: RS4;11 - Unknown function | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 760 | 1 |
ENSG00000056998 | GYG2 | Glycogenin 2 | [
"O15488"
] | X | 2828822-2882820 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005495",
"HPA064686"
] | [
"GN-2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Glycogen biosynthesis"
] | [
"Transferase"
] | [] | [
"Nucleoli",
"Cytosol"
] | [
"Nucleoplasm",
"Mitotic spindle",
"Centrosome"
] | [] | [] | Approved | Enhanced | null | 10 | Yes | No | null | Cluster 44: Non-specific - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 89: Adipocytes - Lipid metabolism | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 7 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | 761 | 5 |
ENSG00000057019 | DCBLD2 | Discoidin, CUB and LCCL domain containing 2 | [
"Q96PD2"
] | 3 | 98795941-98901695 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA016909"
] | [
"CLCP1",
"ESDN"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Approved | null | 1 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 72: Neuronal - Signal transduction | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 6 | 4 | 4 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 762 | 4 |
ENSG00000057149 | SERPINB3 | Serpin family B member 3 | [
"P29508"
] | 18 | 63655197-63661893 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB018772",
"CAB036006",
"CAB036007",
"HPA048341",
"HPA049988",
"HPA055992",
"HPA073892"
] | [
"HsT1196",
"SCC",
"SCCA1",
"T4-A"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Protease inhibitor",
"Serine protease inhibitor"
] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Supported | Enhanced | null | 39 | null | null | null | null | Cluster 71: Lymphoma - Inflammatory response | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 81: Squamous epithelium - Keratinization | Group enriched | Detected in some | 8 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 763 | 6 |
ENSG00000057252 | SOAT1 | Sterol O-acyltransferase 1 | [
"P35610"
] | 1 | 179293714-179358680 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009533",
"HPA047171"
] | [
"ACAT",
"ACAT1",
"SOAT",
"STAT"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Cholesterol metabolism",
"Lipid metabolism",
"Steroid metabolism",
"Sterol metabolism"
] | [
"Acyltransferase",
"Transferase"
] | [
"FDA approved drug targets"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Enhanced | Enhanced | null | 36 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 21: Non-specific - Metabolism | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 764 | 2 |
ENSG00000057294 | PKP2 | Plakophilin 2 | [
"Q99959"
] | 12 | 32790745-32896777 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014314",
"CAB037336",
"HPA056908"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell adhesion"
] | [] | [
"Cardiomyopathy",
"Disease variant"
] | [
"Cell Junctions"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | Enhanced | null | 41 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 29: Forebrain - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 35: Non-specific - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 4 | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 765 | 3 |
ENSG00000057468 | MSH4 | MutS homolog 4 | [
"O15457"
] | 1 | 75796882-75913242 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA028117"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Meiosis"
] | [
"DNA-binding"
] | [
"Disease variant",
"Premature ovarian failure"
] | [
"Nucleoplasm"
] | [
"Equatorial segment",
"Flagellar centriole",
"Mid piece"
] | [] | [] | Approved | null | null | 12 | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 3: Rhabdoid - Membrane components | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 67: Testis - Mixed function | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 766 | 4 |
ENSG00000057593 | F7 | Coagulation factor VII | [
"P08709"
] | 13 | 113105788-113120685 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Candidate cardiovascular disease genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Blood coagulation",
"Hemostasis"
] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [
"Secreted to blood"
] | [
"Blood coagulation"
] | null | null | null | 3 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 53: Liver - Plasma proteins | Tissue enriched | Detected in some | 95 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in some | 15 | Cell type enriched | Detected in some | 22 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Chromophobe"
] | [] | [
"Kidney Chromophobe"
] | 767 | 5 |
ENSG00000057608 | GDI2 | GDP dissociation inhibitor 2 | [
"P50395"
] | 10 | 5765223-5842132 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049290",
"HPA057668"
] | [
"RABGDIB"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Supported | null | 80 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 30: White matter - Myelination | Cluster 52: Non-specific - Mitochondria | Cluster 82: Dendritic cells - Antigen presentation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 768 | 8 |
ENSG00000057657 | PRDM1 | PR/SET domain 1 | [
"O75626"
] | 6 | 105993463-106109939 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030033",
"HPA075427"
] | [
"BLIMP1",
"PRDI-BF1"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Adaptive immunity",
"Immunity",
"Innate immunity",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Methyltransferase",
"Repressor",
"Transferase"
] | [
"Cancer-related genes"
] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 15 | null | null | Cluster 1: T-cells - Unknown function | Cluster 25: Non-specific - Transcription | Cluster 51: Myeloma - Immunoglobulins | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Cancer enriched | Detected in many | 4 | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Group enriched | Detected in many | 4 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 769 | 1 |
ENSG00000057663 | ATG5 | Autophagy related 5 | [
"Q9H1Y0"
] | 6 | 106045423-106325791 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB034432",
"CAB037309",
"HPA042973"
] | [
"APG5",
"APG5L",
"ASP",
"hAPG5"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Apoptosis",
"Autophagy",
"Host-virus interaction",
"Immunity"
] | [] | [
"Disease variant",
"Neurodegeneration"
] | [
"Primary cilium transition zone",
"Centrosome",
"Basal body"
] | [
"Vesicles"
] | [] | [] | Approved | Approved | null | 73 | null | null | Cluster 24: Non-specific - Transcription | Cluster 23: Choroid plexus - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | 770 | 8 |
ENSG00000057704 | TMCC3 | Transmembrane and coiled-coil domain family 3 | [
"Q9ULS5"
] | 12 | 94567122-94650557 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA014272"
] | [
"KIAA1145"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Endoplasmic reticulum"
] | [
"Vesicles"
] | [] | [] | Approved | Approved | null | 7 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 11: White matter - Signal transduction | Cluster 55: Lymphoma - Immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 771 | 7 |
ENSG00000057757 | PITHD1 | PITH domain containing 1 | [
"Q9GZP4"
] | 1 | 23778418-23788232 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA016936"
] | [
"C1orf128",
"HT014",
"TXNL1CL"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 4 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 14: Neurons - Synaptic function | Cluster 37: Non-specific - mRNA processing | Cluster 20: Non-specific - Transcription regulation | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 772 | 1 |
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