ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000038427 | VCAN | Versican | [
"P13611"
] | 5 | 83471618-83582303 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004726",
"CAB008979"
] | [
"CSPG2",
"PG-M"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [
"Cataract"
] | [
"Vesicles",
"Mid piece",
"Principal piece",
"End piece"
] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | Approved | Supported | null | 7 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 2 | 0 | 2 | [] | [
"Ovary Serous Cystadenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Stomach Adenocarcinoma"
] | 547 | 1 |
ENSG00000038532 | CLEC16A | C-type lectin domain containing 16A | [
"Q2KHT3"
] | 16 | 10944539-11182186 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035814",
"HPA035815",
"HPA061385"
] | [
"Gop-1",
"KIAA0350"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Autophagy"
] | [] | [
"Diabetes mellitus"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Approved | Enhanced | null | 10 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 38: Sub-cortical - Mixed function | Cluster 21: Lymphoma - Adaptive immune response | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 548 | 3 |
ENSG00000038945 | MSR1 | Macrophage scavenger receptor 1 | [
"P21757"
] | 8 | 16107878-16567490 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000272",
"CAB032491"
] | [
"CD204",
"SCARA1",
"SR-A",
"SR-AI",
"SR-AII",
"SR-AIII"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Endocytosis"
] | [
"Receptor"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Enhanced | null | 9 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 20: Macrophages & Microglia - Immune response | Cluster 51: Myeloma - Immunoglobulins | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 13: Lung - Secretion | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 549 | 1 |
ENSG00000039068 | CDH1 | Cadherin 1 | [
"P12830"
] | 16 | 68737292-68835537 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000087",
"HPA004812",
"CAB028364",
"CAB072855",
"CAB072856",
"CAB072857"
] | [
"CD324",
"UVO",
"uvomorulin"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Cell adhesion"
] | [] | [
"Cancer-related genes",
"Disease variant",
"Ectodermal dysplasia"
] | [
"Plasma membrane",
"Cell Junctions"
] | [
"Golgi apparatus"
] | [] | [] | Supported | Enhanced | null | 110 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 36: Choroid plexus - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 13 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 550 | 6 |
ENSG00000039123 | MTREX | Mtr4 exosome RNA helicase | [
"P42285"
] | 5 | 55307989-55425579 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037379"
] | [
"Dob1",
"fSAP118",
"KIAA0052",
"Mtr4",
"SKIV2L2"
] | [
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"mRNA processing",
"mRNA splicing",
"rRNA processing"
] | [
"Helicase",
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 66 | null | null | Cluster 18: Non-specific - Translation | Cluster 55: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 551 | 3 |
ENSG00000039523 | RIPOR1 | RHO family interacting cell polarization regulator 1 | [
"Q6ZS17"
] | 16 | 67518418-67546788 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005923"
] | [
"FAM65A",
"FLJ13725"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [
"Cytosol"
] | [] | [] | Supported | Uncertain | null | null | null | null | Cluster 29: Non-specific - Unknown function | Cluster 32: Cerebral cortex - Mixed function | Cluster 68: Non-specific - Cell cycle regulation | Cluster 57: Podocytes - Glomerular filtration | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 6 | Group enriched | Detected in many | 7 | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 554 | 4 |
ENSG00000039537 | C6 | Complement C6 | [
"P13671"
] | 5 | 41142116-41261438 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043823",
"CAB069427"
] | [] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted secreted proteins",
"Transporters"
] | [
"Complement pathway",
"Cytolysis",
"Immunity",
"Innate immunity"
] | [] | [
"Cancer-related genes"
] | [] | [] | [
"Secreted to blood"
] | [
"Complement pathway"
] | null | Enhanced | null | 3 | null | null | null | Cluster 3: Choroid plexus - Cilium | Cluster 44: Connective tissue cells - ECM organization | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 11 | Cancer enhanced | Detected in single | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Liver Hepatocellular Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Stomach Adenocarcinoma"
] | 555 | 5 |
ENSG00000039560 | RAI14 | Retinoic acid induced 14 | [
"Q9P0K7"
] | 5 | 34656328-34832612 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036949",
"HPA036950"
] | [
"DKFZp564G013",
"KIAA1334",
"NORPEG",
"RAI13"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis"
] | [] | [] | [
"Nucleoplasm"
] | [
"Actin filaments",
"Cytosol"
] | [] | [] | Supported | Supported | null | 53 | null | null | null | Cluster 30: White matter - Myelination | Cluster 72: Neuronal - Signal transduction | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 556 | 3 |
ENSG00000039600 | SOX30 | SRY-box transcription factor 30 | [
"O94993"
] | 5 | 157625679-157671480 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006159",
"CAB009382"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm",
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 4 | null | null | Cluster 5: Non-specific - Cell proliferation | null | Cluster 70: DU4475 - Unknown function | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 6: Testis - Spermatogenesis | Tissue enriched | Detected in single | 85 | Cancer enhanced | Detected in single | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 557 | 5 |
ENSG00000039650 | PNKP | Polynucleotide kinase 3'-phosphatase | [
"Q96T60"
] | 19 | 49859882-49878351 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006782"
] | [
"PNK"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"Hydrolase",
"Kinase",
"Multifunctional enzyme",
"Transferase"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability",
"Neurodegeneration",
"Primary microcephaly"
] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | [] | Supported | Supported | null | 58 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 10: Epididymal principal cells - Sperm maturation microenvironment | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 558 | 8 |
ENSG00000039987 | BEST2 | Bestrophin 2 | [
"Q8NFU1"
] | 19 | 12751702-12758458 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA046229"
] | [
"FLJ20132",
"VMD2L1"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Chloride channel",
"Ion channel"
] | [] | [
"Flagellar centriole",
"Principal piece",
"End piece"
] | [] | [] | [] | Approved | Approved | null | 14 | null | null | null | Cluster 25: Non-specific - Transcription | Cluster 56: Non-specific - Sensory perception | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 77: Intestine - Digestion | Group enriched | Detected in some | 6 | Not detected | Not detected | null | Low cancer specificity | Detected in some | null | Cell type enriched | Detected in some | 21 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Rectum Adenocarcinoma"
] | [
"Rectum Adenocarcinoma"
] | 559 | 3 |
ENSG00000040199 | PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 | [
"Q6ZVD8"
] | 16 | 71637835-71724701 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040761",
"HPA041837",
"HPA048598"
] | [
"KIAA0931",
"PHLPPL",
"PPM3B"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [
"Tumor suppressor"
] | [
"Cytokinetic bridge",
"Mitotic spindle",
"Primary cilium",
"Cytosol"
] | [
"Vesicles",
"Primary cilium tip",
"Centriolar satellite",
"Basal body"
] | [] | [] | Supported | Approved | null | 12 | Yes | No | null | Cluster 1: Neurons - Mixed function | Cluster 68: Non-specific - Cell cycle regulation | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 560 | 2 |
ENSG00000040275 | SPDL1 | Spindle apparatus coiled-coil protein 1 | [
"Q96EA4"
] | 5 | 169583636-169604778 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044700",
"HPA048146"
] | [
"CCDC99",
"FLJ20364",
"hSpindly"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 13 | null | Yes | Cluster 22: Eosinophils - Transcription | Cluster 30: White matter - Myelination | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 561 | 6 |
ENSG00000040341 | STAU2 | Staufen double-stranded RNA binding protein 2 | [
"Q9NUL3"
] | 8 | 73420369-73747708 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019155",
"CAB020836",
"HPA075293"
] | [
"39K2"
] | [
"Predicted intracellular proteins"
] | [
"Transport"
] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 41 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 40: Non-specific - Unknown function | Cluster 109: Neurons - Neuronal signaling | Cluster 41: Striated muscle - Muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 562 | 2 |
ENSG00000040487 | SLC66A1 | Solute carrier family 66 member 1 | [
"Q6ZP29"
] | 1 | 19312326-19329300 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA057810"
] | [
"FLJ20320",
"LAAT-1",
"LAAT1",
"PQLC2"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Amino-acid transport",
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | Approved | null | null | null | null | Cluster 29: Non-specific - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 563 | 7 |
ENSG00000040531 | CTNS | Cystinosin, lysosomal cystine transporter | [
"O60931"
] | 17 | 3636459-3663103 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA074687"
] | [
"CTNS-LSB",
"PQLC4",
"SLC66A4"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Melanin biosynthesis",
"Protein transport",
"Symport",
"Transport"
] | [] | [
"Disease variant"
] | [
"Vesicles"
] | [] | [] | [] | Supported | null | null | null | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 11: White matter - Signal transduction | Cluster 50: Lymphoma - Unknown function | Cluster 47: Platelets - Hemostasis | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 564 | 2 |
ENSG00000040608 | RTN4R | Reticulon 4 receptor | [
"Q9BZR6"
] | 22 | 20241415-20283246 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB012443"
] | [
"NOGOR"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [
"Disease variant",
"Schizophrenia"
] | [
"Plasma membrane",
"Focal adhesion sites"
] | [
"Actin filaments"
] | [] | [] | Approved | null | null | 18 | null | null | Cluster 11: T-cells - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 35: RS4;11 - Unknown function | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in many | 7 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 565 | 9 |
ENSG00000040633 | PHF23 | PHD finger protein 23 | [
"Q9BUL5"
] | 17 | 7235029-7239722 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052410",
"HPA077075"
] | [
"FLJ16355",
"MGC2941"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Autophagy",
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 11 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 42: Non-specific - Unknown function | Cluster 84: Apical squamous epithelium - Cornification | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 566 | 2 |
ENSG00000040731 | CDH10 | Cadherin 10 | [
"Q9Y6N8"
] | 5 | 24487100-24644978 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA010651",
"HPA012085"
] | [] | [
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Cell Junctions"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 1 | null | null | null | Cluster 2: Neurons - Nucleosome | Cluster 5: Rhabdoid - Unknown function | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in some | 6 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 567 | 4 |
ENSG00000040933 | INPP4A | Inositol polyphosphate-4-phosphatase type I A | [
"Q96PE3"
] | 2 | 98444854-98594392 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001628"
] | [
"INPP4"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [
"Nucleoplasm",
"Nuclear membrane"
] | [] | [] | [] | Supported | Approved | null | null | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 24: Neurons - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 10: Brain - Synaptic signal transduction | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 568 | 1 |
ENSG00000041353 | RAB27B | RAB27B, member RAS oncogene family | [
"O00194"
] | 18 | 54717860-54895516 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017712",
"HPA019849"
] | [] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [] | [
"Golgi apparatus",
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 23 | null | null | Cluster 24: Non-specific - Transcription | Cluster 14: Neurons - Synaptic function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 58: Mast cells - Allergic inflammatory responses | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 4 | 0 | 4 | [] | [
"Breast Invasive Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 569 | 1 |
ENSG00000041357 | PSMA4 | Proteasome 20S subunit alpha 4 | [
"P25789"
] | 15 | 78540405-78552417 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004973",
"HPA055466",
"HPA060613"
] | [
"HC9",
"HsT17706"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Vesicles",
"Connecting piece",
"Flagellar centriole",
"Mid piece"
] | [] | [] | Supported | Supported | null | 170 | No | No | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 27: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 6 | 0 | 6 | [
"Lung Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 570 | 4 |
ENSG00000041515 | MYO16 | Myosin XVI | [
"Q9Y6X6"
] | 13 | 108596152-109208005 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040110",
"HPA058769",
"HPA071948"
] | [
"KIAA0865",
"Myo16b",
"MYR8",
"NYAP3",
"PPP1R107"
] | [
"Predicted intracellular proteins"
] | [] | [
"Actin-binding",
"Motor protein",
"Myosin"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | 2 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in many | 7 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 571 | 2 |
ENSG00000041802 | LSG1 | Large 60S subunit nuclear export GTPase 1 | [
"Q9H089"
] | 3 | 194640791-194672463 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037704",
"HPA037705"
] | [
"FLJ11301"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [
"Hydrolase"
] | [] | [
"Nuclear bodies",
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 30 | No | No | Cluster 12: Non-specific - Mitochondrial translation | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 63: Non-specific - Protein processing | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 572 | 8 |
ENSG00000041880 | PARP3 | Poly(ADP-ribose) polymerase family member 3 | [
"Q9Y6F1"
] | 3 | 51942345-51948867 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020984",
"HPA067657"
] | [
"ADPRT3",
"ADPRTL3",
"ARTD3",
"hPARP-3",
"IRT1",
"pADPRT-3"
] | [
"FDA approved drug targets",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"Glycosyltransferase",
"Nucleotidyltransferase",
"Transferase"
] | [
"FDA approved drug targets"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [] | [] | [] | Supported | Supported | null | 5 | Yes | No | Cluster 12: Non-specific - Mitochondrial translation | Cluster 19: Astrocytes - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 573 | 3 |
ENSG00000041982 | TNC | Tenascin C | [
"P24821"
] | 9 | 115019575-115118207 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004592",
"HPA004823"
] | [
"DFNA56",
"HXB",
"MGC167029",
"TN"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [
"Cancer-related genes",
"Deafness",
"Disease variant",
"Non-syndromic deafness"
] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Cell adhesion"
] | null | Approved | null | 4 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 574 | 7 |
ENSG00000041988 | THAP3 | THAP domain containing 3 | [
"Q8WTV1"
] | 1 | 6624868-6635586 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA067114"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Mitochondria"
] | [] | [] | Approved | Approved | null | 18 | No | No | Cluster 5: Non-specific - Cell proliferation | Cluster 6: Non-specific - Immune response | Cluster 35: RS4;11 - Unknown function | Cluster 110: Mural cells - ECM organization | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 575 | 8 |
ENSG00000042062 | RIPOR3 | RIPOR family member 3 | [
"Q96MK2"
] | 20 | 50586108-50691542 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051823",
"HPA054759"
] | [
"C20orf175",
"C20orf176",
"dJ530I15.2",
"dJ530I15.3",
"FAM65C"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 6 | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 64: Connective tissue cells - ECM organization | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 576 | 8 |
ENSG00000042088 | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | [
"Q9NUW8"
] | 14 | 89954939-90044764 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA071317"
] | [
"FLJ11090",
"SCAN1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"Exonuclease",
"Hydrolase",
"Nuclease"
] | [
"Disease variant",
"Neurodegeneration"
] | [
"Nucleoplasm"
] | [
"Plasma membrane"
] | [] | [] | Supported | Approved | null | 27 | No | No | Cluster 5: Non-specific - Cell proliferation | Cluster 31: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 577 | 9 |
ENSG00000042286 | AIFM2 | Apoptosis inducing factor mitochondria associated 2 | [
"Q9BRQ8"
] | 10 | 70098223-70132934 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028961",
"HPA042309",
"HPA075576"
] | [
"AMID",
"FLJ14497",
"FSP1",
"PRG3"
] | [
"Predicted intracellular proteins"
] | [] | [
"DNA-binding",
"Oxidoreductase"
] | [] | [
"Vesicles"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | Supported | Approved | null | 7 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 7: Liver cancer - Metabolism | Cluster 89: Adipocytes - Lipid metabolism | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 578 | 5 |
ENSG00000042317 | SPATA7 | Spermatogenesis associated 7 | [
"Q9P0W8"
] | 14 | 88384924-88470350 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038082",
"HPA038083"
] | [
"HSD3",
"LCA3"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Sensory transduction",
"Vision"
] | [] | [
"Leber congenital amaurosis",
"Retinitis pigmentosa"
] | [
"Vesicles",
"Primary cilium transition zone",
"Mid piece"
] | [] | [] | [] | Supported | Enhanced | null | null | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 16: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 21: Testis - Mixed function | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 579 | 2 |
ENSG00000042429 | MED17 | Mediator complex subunit 17 | [
"Q9NVC6"
] | 11 | 93784227-93814963 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA046619"
] | [
"CRSP6",
"CRSP77",
"DRIP80",
"SRB4",
"TRAP80"
] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Nuclear speckles"
] | [
"Cytosol"
] | [] | [] | Approved | null | null | 165 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 16: Non-specific - Transcription | Cluster 24: Non-specific - Unknown function | Cluster 22: Non-specific - Basic cellular functions | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe"
] | 580 | 2 |
ENSG00000042445 | RETSAT | Retinol saturase | [
"Q6NUM9"
] | 2 | 85341955-85354531 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA007961"
] | [
"FLJ20296"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Lipid metabolism"
] | [
"Oxidoreductase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 24 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 39: Astrocytes - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 26: Kidney & Intestine - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 581 | 8 |
ENSG00000042493 | CAPG | Capping actin protein, gelsolin like | [
"P40121"
] | 2 | 85394753-85418432 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018843",
"HPA019080",
"HPA019092"
] | [
"AFCP",
"MCP"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin capping",
"Actin-binding"
] | [] | [
"Nucleoplasm"
] | [
"Mitotic chromosome"
] | [] | [] | Supported | Enhanced | null | 5 | Yes | No | Cluster 10: Non-specific - Membrane trafficking | Cluster 20: Macrophages & Microglia - Immune response | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 5 | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 582 | 4 |
ENSG00000042753 | AP2S1 | Adaptor related protein complex 2 subunit sigma 1 | [
"P53680"
] | 19 | 46838136-46850846 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CLAPS2",
"FBH3",
"FBHOk",
"HHC3"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Endocytosis",
"Protein transport",
"Transport"
] | [] | [
"Disease variant"
] | [] | [] | [] | [] | null | null | null | 53 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 4: Non-specific - Transcription | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 583 | 6 |
ENSG00000042781 | USH2A | Usherin | [
"O75445"
] | 1 | 215622891-216423448 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045176"
] | [
"RP39",
"USH2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Hearing",
"Sensory transduction",
"Vision"
] | [] | [
"Deafness",
"Disease variant",
"Retinitis pigmentosa",
"Usher syndrome"
] | [
"Acrosome",
"Equatorial segment",
"Mid piece",
"Principal piece"
] | [
"End piece"
] | [
"Intracellular and membrane"
] | [
"Other"
] | Approved | null | null | null | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 11: Neuronal - Sensory perception | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Group enriched | Detected in some | 21 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in many | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 584 | 5 |
ENSG00000042813 | ZPBP | Zona pellucida binding protein | [
"Q9BS86"
] | 7 | 49850421-50121329 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA058673"
] | [
"SP38",
"ZPBP1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted in male reproductive system"
] | [
"No annotated function"
] | null | Enhanced | null | null | null | null | null | null | Cluster 6: Leukemia - Signal transduction | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in some | 31 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 585 | 4 |
ENSG00000042832 | TG | Thyroglobulin | [
"P01266"
] | 8 | 132866958-133134903 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000077",
"HPA002740",
"CAB056155"
] | [
"AITD3",
"TGN"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Thyroid hormones biosynthesis"
] | [
"Hormone",
"Thyroid hormone"
] | [
"Cancer-related genes",
"Congenital hypothyroidism",
"Disease variant"
] | [] | [] | [
"Secreted in other tissues"
] | [
"Hormone"
] | null | Enhanced | null | 2 | null | null | Cluster 4: Neutrophils - Degranulation | Cluster 29: Forebrain - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 33: Thyroid gland - Tissue development | Tissue enriched | Detected in many | 685 | Cancer enriched | Detected in some | 9 | Cancer enriched | Detected in many | 1,546 | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 586 | 4 |
ENSG00000042980 | ADAM28 | ADAM metallopeptidase domain 28 | [
"Q9UKQ2"
] | 8 | 24294069-24359014 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA074034"
] | [
"ADAM23",
"eMDCII",
"MDC-Lm",
"MDC-Ls"
] | [
"Plasma proteins",
"Predicted membrane proteins",
"Predicted secreted proteins",
"Transporters"
] | [] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [
"Plasma membrane"
] | [
"Mitochondria"
] | [
"Secreted to blood"
] | [
"Enzyme"
] | Approved | Enhanced | null | 1 | null | null | Cluster 32: Basophils - Transcription | Cluster 20: Macrophages & Microglia - Immune response | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 50: Epididymis - Male reproductive secretion | Group enriched | Detected in many | 6 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 587 | 3 |
ENSG00000043039 | BARX2 | BARX homeobox 2 | [
"Q9UMQ3"
] | 11 | 129375848-129452279 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB033311",
"HPA064966",
"HPA068414"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Golgi apparatus",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 2 | null | null | null | Cluster 21: Non-specific - Metabolism | Cluster 21: Lymphoma - Adaptive immune response | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 588 | 4 |
ENSG00000043093 | DCUN1D1 | Defective in cullin neddylation 1 domain containing 1 | [
"Q96GG9"
] | 3 | 182938074-182985953 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035911"
] | [
"DCUN1L1",
"RP42",
"SCCRO",
"SCRO",
"Tes3"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 35 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 28: Oligodendrocytes - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in all | 6 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 8 | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 589 | 4 |
ENSG00000043143 | JADE2 | Jade family PHD finger 2 | [
"Q9NQC1"
] | 5 | 134524312-134583230 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA025959",
"HPA055789"
] | [
"JADE-2",
"KIAA0239",
"PHF15"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 11 | null | null | Cluster 16: Non-specific - Cell proliferation | Cluster 6: Non-specific - Immune response | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 590 | 5 |
ENSG00000043355 | ZIC2 | Zic family member 2 | [
"O95409"
] | 13 | 99981784-99986765 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055031"
] | [
"HPE5"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding",
"Repressor"
] | [
"Disease variant",
"Holoprosencephaly"
] | [
"Nuclear bodies"
] | [] | [] | [] | Supported | null | null | 4 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 10: Ciliated cells - Ion channel activity | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 71: Cerebellum - Nervous system development | Tissue enriched | Detected in some | 8 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 591 | 1 |
ENSG00000043462 | LCP2 | Lymphocyte cytosolic protein 2 | [
"Q13094"
] | 5 | 170246233-170297815 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004574",
"HPA036396",
"HPA036397"
] | [
"SLP-76",
"SLP76"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 39 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 49: HMC-1 - Innate immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Group enriched | Detected in many | 4 | Cancer enriched | Detected in some | 4 | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 592 | 7 |
ENSG00000043514 | TRIT1 | TRNA isopentenyltransferase 1 | [
"Q9H3H1"
] | 1 | 39838110-39883511 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024174",
"HPA027330"
] | [
"FLJ20061",
"IPT"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [
"Transferase"
] | [
"Disease variant",
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Approved | null | 1 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 31: Non-specific - Transcription | Cluster 10: Ciliated cells - Ion channel activity | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 2: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 593 | 7 |
ENSG00000043591 | ADRB1 | Adrenoceptor beta 1 | [
"P08588"
] | 10 | 114043866-114046904 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA067972"
] | [
"ADRB1R"
] | [
"FDA approved drug targets",
"G-protein coupled receptors",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | 7 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in some | 4 | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma"
] | 594 | 8 |
ENSG00000044012 | GUCA2B | Guanylate cyclase activator 2B | [
"Q16661"
] | 1 | 42153410-42155820 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | null | null | null | 2 | null | null | Cluster 40: Monocytes - Innate immune response | null | Cluster 40: Non-specific - Unknown function | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Tissue enriched | Detected in some | 8 | Cancer enriched | Detected in single | 24 | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 7 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 595 | 1 |
ENSG00000044090 | CUL7 | Cullin 7 | [
"Q14999"
] | 6 | 43037617-43053943 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB015449",
"HPA030095",
"HPA030096"
] | [
"dJ20C7.5",
"KIAA0076"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Ubl conjugation pathway"
] | [] | [
"Disease variant",
"Dwarfism"
] | [] | [] | [] | [] | null | Approved | null | 77 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 28: Non-specific - Nuclear processes | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 596 | 3 |
ENSG00000044115 | CTNNA1 | Catenin alpha 1 | [
"P35221"
] | 5 | 138610967-138935034 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB021089",
"HPA046119",
"HPA063535"
] | [
"CAP102"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Plasma membrane",
"Cell Junctions"
] | [
"Golgi apparatus",
"Vesicles",
"Connecting piece",
"Mid piece",
"Principal piece"
] | [] | [] | Supported | Supported | null | 73 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 11: White matter - Signal transduction | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 597 | 7 |
ENSG00000044446 | PHKA2 | Phosphorylase kinase regulatory subunit alpha 2 | [
"P46019"
] | X | 18892298-18984114 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002912"
] | [
"PHK",
"PYK"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism",
"Glycogen metabolism"
] | [
"Calmodulin-binding"
] | [
"Disease variant",
"Glycogen storage disease"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 33 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 6: Non-specific - Immune response | Cluster 36: Non-specific - mRNA processing | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 26: Kidney & Intestine - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 598 | 3 |
ENSG00000044574 | HSPA5 | Heat shock protein family A (Hsp70) member 5 | [
"P11021"
] | 9 | 125234853-125241382 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005221",
"HPA038845",
"HPA038846"
] | [
"BiP",
"GRP78"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Host-virus interaction"
] | [
"Chaperone",
"Hydrolase"
] | [] | [
"Cytosol",
"Annulus"
] | [
"Mid piece",
"Principal piece",
"End piece"
] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Uncertain | Enhanced | null | 449 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 8: Non-specific - Secretory pathway | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | 601 | 4 |
ENSG00000046604 | DSG2 | Desmoglein 2 | [
"Q14126"
] | 18 | 31498177-31549008 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004896",
"CAB025122"
] | [
"CDHF5"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [
"Cardiomyopathy",
"Disease variant"
] | [
"Cell Junctions"
] | [
"Vesicles",
"Plasma membrane"
] | [] | [] | Supported | Enhanced | null | 29 | null | null | Cluster 41: Basophils - Unknown function | Cluster 36: Choroid plexus - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 12 | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 602 | 1 |
ENSG00000046647 | GEMIN8 | Gem nuclear organelle associated protein 8 | [
"Q9NWZ8"
] | X | 14006726-14029893 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028613"
] | [
"FAM51A1",
"FLJ20514"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 44 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 30: White matter - Myelination | Cluster 36: Non-specific - mRNA processing | Cluster 7: Non-specific - Transcription | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 603 | 6 |
ENSG00000046651 | OFD1 | OFD1 centriole and centriolar satellite protein | [
"O75665"
] | X | 13734743-13777955 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031102",
"HPA031103",
"HPA031104"
] | [
"71-7A",
"CXorf5",
"JBTS10",
"RP23"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [
"Ciliopathy",
"Disease variant",
"Joubert syndrome",
"Retinitis pigmentosa"
] | [
"Microtubules"
] | [
"Primary cilium",
"End piece"
] | [] | [] | Uncertain | Approved | null | 74 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 34: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enriched | Detected in all | 6 | 0 | 0 | 0 | [] | [] | [] | 604 | 7 |
ENSG00000046653 | GPM6B | Glycoprotein M6B | [
"Q13491"
] | X | 13770939-13938638 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002913"
] | [
"M6B",
"MGC17150",
"MGC54284"
] | [
"Predicted membrane proteins"
] | [
"Differentiation",
"Neurogenesis",
"Osteogenesis",
"Protein transport",
"Transport"
] | [
"Developmental protein"
] | [] | [] | [] | [] | [] | null | Approved | null | 2 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 30: White matter - Myelination | Cluster 72: Neuronal - Signal transduction | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 3: Oligodendrocytes - Myelination | Group enriched | Detected in many | 14 | Group enriched | Detected in many | 5 | Cancer enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 230 | 2 | 0 | 2 | [
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 605 | 7 |
ENSG00000046774 | MAGEC2 | MAGE family member C2 | [
"Q9UBF1"
] | X | 142202342-142205290 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA062230"
] | [
"CT10",
"HCA587",
"MAGE-C2",
"MAGEE1"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Tumor antigen"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 19 | Yes | null | null | null | Cluster 51: Myeloma - Immunoglobulins | Cluster 106: Spermatogonia - Spermatogonial differentiation | Cluster 6: Testis - Spermatogenesis | Tissue enriched | Detected in single | 184 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 75 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 606 | 2 |
ENSG00000046889 | PREX2 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 | [
"Q70Z35"
] | 8 | 67952046-68237032 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015234",
"HPA075956"
] | [
"DEP.2",
"DEPDC2",
"FLJ12987",
"P-REX2",
"PPP1R129"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [
"Cancer-related genes"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Enhanced | null | 3 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 43: Placenta - Pregnancy hormone signaling | Low tissue specificity | Detected in many | null | Group enriched | Detected in some | 6 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 607 | 3 |
ENSG00000047056 | WDR37 | WD repeat domain 37 | [
"Q9Y2I8"
] | 10 | 1049538-1160991 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037376",
"HPA037565"
] | [
"KIAA0982"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant"
] | [
"Intermediate filaments"
] | [] | [] | [] | Approved | Enhanced | null | 11 | No | No | Cluster 15: NK-cells - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 52: Non-specific - Mitochondria | Cluster 55: Myocytes - Oxidative muscle function | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 7 | 0 | 7 | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Thyroid Carcinoma"
] | 608 | 6 |
ENSG00000047188 | YTHDC2 | YTH domain containing 2 | [
"Q9H6S0"
] | 5 | 113513694-113595285 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA037364",
"HPA072678"
] | [
"DKFZp564A186",
"FLJ10053",
"FLJ2194"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Meiosis",
"Oogenesis",
"Spermatogenesis"
] | [
"Helicase",
"Hydrolase",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Cytoplasmic bodies"
] | [] | [] | Approved | Approved | null | 59 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 31: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 42: Retina - Visual perception | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 609 | 6 |
ENSG00000047230 | CTPS2 | CTP synthase 2 | [
"Q9NRF8"
] | X | 16587999-16712936 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA017437",
"HPA075930"
] | [
"GATD5B"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Pyrimidine biosynthesis"
] | [
"Ligase"
] | [] | [
"Mitochondria",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 40 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 55: Non-specific - Transcription | Cluster 36: Non-specific - mRNA processing | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 610 | 9 |
ENSG00000047249 | ATP6V1H | ATPase H+ transporting V1 subunit H | [
"Q9UI12"
] | 8 | 53715543-53843558 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009532",
"HPA023421"
] | [
"CGI-11",
"SFD",
"SFDalpha",
"SFDbeta",
"VMA13"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Host-virus interaction",
"Hydrogen ion transport",
"Ion transport",
"Transport"
] | [] | [] | [
"Actin filaments",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Supported | Approved | null | 41 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 14: Neurons - Synaptic function | Cluster 40: Non-specific - Unknown function | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 611 | 6 |
ENSG00000047315 | POLR2B | RNA polymerase II subunit B | [
"P30876"
] | 4 | 56977722-57031158 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037506"
] | [
"RPB2"
] | [
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"RNA polymerase related proteins"
] | [
"Transcription"
] | [
"Hydrolase",
"Nucleotidyltransferase",
"RNA-directed RNA polymerase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 228 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 31: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 612 | 2 |
ENSG00000047346 | ATOSA | Atos homolog A | [
"Q32MH5"
] | 15 | 52581317-52709817 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039369",
"HPA040180"
] | [
"FAM214A",
"FLJ10980",
"KIAA1370"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 5 | null | null | Cluster 24: Non-specific - Transcription | Cluster 50: Non-specific - Nucleic acid binding | Cluster 46: Lymphoma - Humoral immune response | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 613 | 8 |
ENSG00000047365 | ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | [
"Q8WZ64"
] | 4 | 35948221-36244514 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035925"
] | [
"CENTD1",
"PARX"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Focal adhesion sites"
] | [
"Actin filaments"
] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 11: White matter - Signal transduction | Cluster 71: Lymphoma - Inflammatory response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 614 | 3 |
ENSG00000047410 | TPR | Translocated promoter region, nuclear basket protein | [
"P12270"
] | 1 | 186311652-186375693 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019661",
"HPA019663",
"HPA024336"
] | [] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Cell cycle",
"Cell division",
"Mitosis",
"mRNA transport",
"Protein transport",
"Translocation",
"Transport"
] | [] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability",
"Proto-oncogene"
] | [
"Nuclear membrane"
] | [] | [] | [] | Enhanced | Enhanced | null | 38 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 55: Non-specific - Transcription | Cluster 45: Non-specific - Nuclear processes | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 615 | 4 |
ENSG00000047457 | CP | Ceruloplasmin | [
"P00450"
] | 3 | 149162410-149221829 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001834",
"CAB008591"
] | [
"AB073614"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins",
"Transporters"
] | [] | [
"Oxidoreductase"
] | [
"Cancer-related genes"
] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Supported | null | 11 | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 616 | 5 |
ENSG00000047578 | KATNIP | Katanin interacting protein | [
"O60303"
] | 16 | 27550133-27780344 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035089",
"HPA035090"
] | [
"JBTS26",
"KIAA0556"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Ciliopathy",
"Joubert syndrome"
] | [
"Nucleoplasm",
"Basal body"
] | [
"Primary cilium",
"Centriolar satellite"
] | [] | [] | Approved | Enhanced | null | 8 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 3: Choroid plexus - Cilium | Cluster 1: Neuronal - Visual perception | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 1 | 0 | 1 | [] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe"
] | 617 | 3 |
ENSG00000047579 | DTNBP1 | Dystrobrevin binding protein 1 | [
"Q96EV8"
] | 6 | 15522807-15663058 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028053",
"HPA029615",
"HPA029616"
] | [
"BLOC1S8",
"DBND",
"Dysbindin",
"HPS7",
"My031"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Sensory transduction"
] | [] | [
"Albinism",
"Hermansky-Pudlak syndrome",
"Schizophrenia"
] | [
"Microtubules"
] | [
"Midbody"
] | [] | [] | Enhanced | Approved | null | 61 | Yes | No | Cluster 14: Non-specific - Unknown function | Cluster 33: Neurons - Mixed function | Cluster 28: Non-specific - Nuclear processes | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 618 | 6 |
ENSG00000047597 | XK | X-linked Kx blood group antigen, Kell and VPS13A binding protein | [
"P51811"
] | X | 37685791-37732130 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019036"
] | [
"Kx",
"NA",
"NAC",
"X1k",
"XKR1"
] | [
"Blood group antigen proteins",
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Amino-acid transport",
"Transport"
] | [
"Blood group antigen"
] | [
"Disease variant"
] | [
"Mitochondria"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | Approved | Approved | null | null | No | No | Cluster 22: Eosinophils - Transcription | Cluster 1: Neurons - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 47: Platelets - Hemostasis | Cluster 34: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 53 | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 619 | 5 |
ENSG00000047617 | ANO2 | Anoctamin 2 | [
"Q9NQ90"
] | 12 | 5531869-5946232 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036276",
"HPA057499"
] | [
"C12orf3",
"TMEM16B"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Chloride channel",
"Ion channel"
] | [] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | null | null | null | null | Cluster 47: Endothelial cells - Vasculature | Cluster 1: Neuronal - Visual perception | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in many | 22 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 5 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 620 | 8 |
ENSG00000047621 | C12orf4 | Chromosome 12 open reading frame 4 | [
"Q9NQ89"
] | 12 | 4487735-4538508 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037871"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Nuclear bodies"
] | [] | [] | [] | Approved | Uncertain | null | 9 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 34: Non-specific - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 621 | 1 |
ENSG00000047634 | SCML1 | Scm polycomb group protein like 1 | [
"Q9UN30"
] | X | 17737449-17754988 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035270",
"HPA035271",
"HPA061397"
] | [] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Enhanced | null | 10 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 37: Neurons - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 47: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 622 | 1 |
ENSG00000047644 | WWC3 | WWC family member 3 | [
"Q9ULE0"
] | X | 10015254-10144474 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039814"
] | [
"BM042",
"KIAA1280"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [] | [
"Cytosol"
] | [
"Actin filaments"
] | [] | [] | Approved | Uncertain | null | 5 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 13: Oligodendrocytes - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 623 | 8 |
ENSG00000047648 | ARHGAP6 | Rho GTPase activating protein 6 | [
"O43182"
] | X | 11117651-11665920 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001798",
"HPA002715",
"HPA036779",
"HPA064390"
] | [
"rhoGAPX-1"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Cytosol"
] | [
"Mitotic spindle"
] | [] | [] | Supported | Enhanced | null | null | Yes | null | null | Cluster 21: Non-specific - Metabolism | Cluster 60: Prostate cancer - Unknown function | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Cancer enriched | Detected in many | 6 | Group enriched | Detected in many | 4 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 624 | 3 |
ENSG00000047662 | FAM184B | Family with sequence similarity 184 member B | [
"Q9ULE4"
] | 4 | 17629306-17781621 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA044119",
"HPA048458"
] | [
"KIAA1276"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 1 | null | null | null | Cluster 32: Cerebral cortex - Mixed function | Cluster 11: Neuronal - Sensory perception | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Prostate Adenocarcinoma"
] | [
"Prostate Adenocarcinoma"
] | 625 | 7 |
ENSG00000047849 | MAP4 | Microtubule associated protein 4 | [
"P27816"
] | 3 | 47850690-48089272 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038149",
"HPA038150"
] | [] | [
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"FDA approved drug targets"
] | [
"Plasma membrane",
"Microtubules",
"Primary cilium",
"Cytosol"
] | [
"Basal body",
"Acrosome",
"Equatorial segment"
] | [] | [] | Approved | Enhanced | null | 75 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 19: Astrocytes - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 626 | 8 |
ENSG00000047932 | GOPC | Golgi associated PDZ and coiled-coil motif containing | [
"Q9HD26"
] | 6 | 117560269-117602542 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019477",
"HPA024018"
] | [
"CAL",
"dJ94G16.2",
"FIG",
"GOPC1",
"PIST"
] | [
"Cancer-related genes",
"Disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [
"Cancer-related genes"
] | [
"Golgi apparatus"
] | [
"Calyx",
"Connecting piece",
"Mid piece",
"Principal piece"
] | [] | [] | Supported | Approved | null | 60 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 34: Non-specific - Mixed function | Cluster 28: Non-specific - Nuclear processes | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 627 | 4 |
ENSG00000048028 | USP28 | Ubiquitin specific peptidase 28 | [
"Q96RU2"
] | 11 | 113797874-113875572 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006778",
"HPA006779"
] | [
"KIAA1515"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Supported | Enhanced | null | 14 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 2: Neurons - Nucleosome | Cluster 24: Non-specific - Unknown function | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 41: Striated muscle - Muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 629 | 6 |
ENSG00000048052 | HDAC9 | Histone deacetylase 9 | [
"Q9UKV0"
] | 7 | 18086949-19002416 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA028926"
] | [
"HD7",
"HDAC",
"HDAC7B",
"KIAA0744",
"MITR"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Hydrolase",
"Repressor"
] | [
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [
"Mitotic chromosome"
] | [] | [] | Approved | Uncertain | null | 19 | Yes | null | Cluster 2: Dendritic cells - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 32: Retina & Lymphoid tissues - Signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 630 | 8 |
ENSG00000048140 | TSPAN17 | Tetraspanin 17 | [
"Q96FV3"
] | 5 | 176647387-176659054 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [
"HPA030447"
] | [
"FBX23",
"FBXO23",
"TM4SF17"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | Cluster 33: Non-specific - ATP binding | Cluster 51: Neurons - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 631 | 5 |
ENSG00000048162 | NOP16 | NOP16 nucleolar protein | [
"Q9Y3C1"
] | 5 | 176383946-176388927 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036506",
"HPA058147"
] | [
"HSPC111",
"HSPC185",
"LOC51491"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli"
] | [] | [] | [] | Enhanced | Approved | null | 69 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 34: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 4 | 2 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Prostate Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Prostate Adenocarcinoma"
] | 632 | 1 |
ENSG00000048342 | CC2D2A | Coiled-coil and C2 domain containing 2A | [
"Q9P2K1"
] | 4 | 15469865-15601552 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044124"
] | [
"JBTS9",
"KIAA1345",
"MKS6"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [
"Ciliopathy",
"Disease variant",
"Joubert syndrome",
"Meckel syndrome",
"Retinitis pigmentosa"
] | [
"Connecting piece",
"Mid piece"
] | [
"Perinuclear theca",
"Principal piece"
] | [] | [] | Approved | Approved | null | 9 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 23: Choroid plexus - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 633 | 8 |
ENSG00000048392 | RRM2B | Ribonucleotide reductase regulatory TP53 inducible subunit M2B | [
"Q7LG56"
] | 8 | 102204502-102238961 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB006854",
"HPA028812"
] | [
"p53R2"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Deoxyribonucleotide synthesis",
"DNA damage",
"DNA repair"
] | [
"Oxidoreductase"
] | [
"Deafness",
"Disease variant",
"FDA approved drug targets",
"Neuropathy",
"Primary mitochondrial disease",
"Progressive external ophthalmoplegia"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | Approved | null | 8 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 46: Lymphoma - Humoral immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 634 | 1 |
ENSG00000048462 | TNFRSF17 | TNF receptor superfamily member 17 | [
"Q02223"
] | 16 | 11965210-11968068 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA010569"
] | [
"BCM",
"BCMA",
"CD269",
"TNFRSF13A"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"FDA approved drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Adaptive immunity",
"Immunity"
] | [
"Receptor"
] | [
"Cancer-related genes",
"FDA approved drug targets",
"Proto-oncogene"
] | [
"Golgi apparatus"
] | [
"Mitotic spindle"
] | [] | [] | Approved | null | null | 4 | Yes | null | Cluster 23: B-cells - Immunoglobulins | Cluster 34: Non-specific - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 34: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in some | 9 | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in some | 20 | Group enriched | Detected in some | 63 | 3 | 0 | 3 | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 636 | 5 |
ENSG00000048540 | LMO3 | LIM domain only 3 | [
"Q8TAP4"
] | 12 | 16548372-16610594 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"DAT1",
"RBTNL2",
"Rhom-3"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [] | [] | [] | [] | [] | null | null | null | 21 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 81: Alveolar cells - Lung function | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Uterine Corpus Endometrial Carcinoma"
] | [
"Uterine Corpus Endometrial Carcinoma"
] | 638 | 5 |
ENSG00000048545 | GUCA1A | Guanylate cyclase activator 1A | [
"P43080"
] | 6 | 42173364-42181338 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005561",
"HPA075056"
] | [
"C6orf131",
"COD3",
"CORD14",
"dJ139D8.6",
"GCAP",
"GCAP1",
"GUCA",
"GUCA1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Sensory transduction",
"Vision"
] | [] | [
"Cone-rod dystrophy",
"Disease variant"
] | [
"Plasma membrane"
] | [] | [] | [] | Uncertain | Supported | null | 7 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 1: Neuronal - Visual perception | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in some | 42 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in some | 4 | Group enriched | Detected in some | 5 | Immune cell enriched | Detected in single | 7 | 0 | 0 | 0 | [] | [] | [] | 640 | 1 |
ENSG00000048707 | VPS13D | Vacuolar protein sorting 13 homolog D | [
"Q5THJ4"
] | 1 | 12230030-12512047 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA027332",
"HPA051621"
] | [
"BLTP5D",
"FLJ10619",
"KIAA0453"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Lipid transport",
"Transport"
] | [] | [
"Disease variant",
"Neurodegeneration"
] | [
"Nucleoplasm",
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 7 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 37: Non-specific - mRNA processing | Cluster 110: Mural cells - ECM organization | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 642 | 7 |
ENSG00000048740 | CELF2 | CUGBP Elav-like family member 2 | [
"O95319"
] | 10 | 10798397-11336675 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016395",
"HPA035813"
] | [
"BRUNOL3",
"CUGBP2",
"Etr-3",
"NAPOR-2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"mRNA processing"
] | [
"Repressor",
"RNA-binding"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Vesicles",
"Midbody ring"
] | [] | [] | Supported | Enhanced | null | 2 | Yes | No | Cluster 35: Neutrophils - Protein binding | Cluster 51: Neurons - Mixed function | Cluster 49: HMC-1 - Innate immune response | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 61: Non-specific - Transcription | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 643 | 5 |
ENSG00000048828 | FAM120A | Family with sequence similarity 120A | [
"Q9NZB2"
] | 9 | 93451685-93566112 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019734",
"HPA055800"
] | [
"C9orf10",
"KIAA0183",
"OSSA"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"RNA-binding"
] | [
"Tumor suppressor"
] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 65 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 8: Immune cells - Immune response | Cluster 43: Non-specific - Basic cellular processes | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 644 | 7 |
ENSG00000048991 | R3HDM1 | R3H domain containing 1 | [
"Q15032"
] | 2 | 135531455-135725270 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030936"
] | [
"KIAA0029",
"R3HDM"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | null | null | 19 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 53: Neurons - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 10: Brain - Synaptic signal transduction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Thyroid Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Thyroid Carcinoma"
] | 645 | 6 |
ENSG00000049089 | COL9A2 | Collagen type IX alpha 2 chain | [
"Q14055"
] | 1 | 40300489-40317813 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA056316",
"HPA075286"
] | [
"EDM2",
"MED"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [
"Deafness",
"Disease variant",
"Dwarfism",
"Stickler syndrome"
] | [
"Vesicles"
] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | Approved | Supported | null | 4 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 6: Non-specific - Immune response | Cluster 11: Neuronal - Sensory perception | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 3: Oligodendrocytes - Myelination | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 4 | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 646 | 9 |
ENSG00000049130 | KITLG | KIT ligand | [
"P21583"
] | 12 | 88492793-88580851 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA070395"
] | [
"DFNA69",
"FPH2",
"Kitl",
"KL-1",
"MGF",
"SCF",
"SF",
"SLF"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"RAS pathway related proteins"
] | [
"Cell adhesion"
] | [
"Growth factor"
] | [
"Cancer-related genes",
"Deafness",
"Disease variant",
"Non-syndromic deafness",
"Waardenburg syndrome"
] | [
"Vesicles"
] | [] | [
"Intracellular and membrane"
] | [
"Growth factor"
] | Approved | Approved | null | 3 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 32: Non-specific - Cell proliferation | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 13: Lung - Secretion | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 647 | 2 |
ENSG00000049167 | ERCC8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit | [
"Q13216"
] | 5 | 60866454-60945073 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA029328"
] | [
"CKN1",
"CSA"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Ubl conjugation pathway"
] | [] | [
"Cockayne syndrome",
"Deafness",
"Disease variant",
"Dwarfism"
] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | null | null | 35 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 9: Non-specific - Receptor signaling | Cluster 30: Non-specific - Gene expression regulation | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 648 | 5 |
ENSG00000049192 | ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif 6 | [
"Q9UKP5"
] | 5 | 65148738-65481920 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA043441"
] | [
"ADAM-TS6"
] | [
"Cancer-related genes",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Cancer-related genes"
] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Enzyme"
] | null | Enhanced | null | null | null | Yes | null | Cluster 43: Hindbrain - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Not detected | Not detected | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 649 | 3 |
ENSG00000049239 | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase | [
"O95479"
] | 1 | 9234774-9271337 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004824",
"HPA005440"
] | [
"GDH",
"H6PDH"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism",
"Glucose metabolism"
] | [
"Hydrolase",
"Multifunctional enzyme",
"Oxidoreductase"
] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Uncertain | Approved | null | 12 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 44: Connective tissue cells - ECM organization | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 650 | 7 |
ENSG00000049245 | VAMP3 | Vesicle associated membrane protein 3 | [
"Q15836"
] | 1 | 7771296-7781432 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CEB"
] | [
"Cancer-related genes",
"Predicted membrane proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | null | null | 194 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 30: White matter - Myelination | Cluster 37: Non-specific - mRNA processing | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 651 | 1 |
ENSG00000049246 | PER3 | Period circadian regulator 3 | [
"P56645"
] | 1 | 7784291-7845177 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019530"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 4 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 2: Neurons - Nucleosome | Cluster 10: Ciliated cells - Ion channel activity | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 46: Brain & retina - Neuronal signaling | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 652 | 9 |
ENSG00000049247 | UTS2 | Urotensin 2 | [
"O95399"
] | 1 | 7843083-7853512 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA017000"
] | [
"PRO1068",
"U-II",
"UCN2",
"UII"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Hormone"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Hormone"
] | null | Uncertain | null | null | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 43: Hindbrain - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 58: Mast cells - Allergic inflammatory responses | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in many | 9 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in many | 5 | 1 | 0 | 1 | [] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma"
] | 653 | 4 |
ENSG00000049249 | TNFRSF9 | TNF receptor superfamily member 9 | [
"Q07011"
] | 1 | 7915871-7943165 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA071425"
] | [
"4-1BB",
"CD137",
"ILA"
] | [
"Cancer-related genes",
"CD markers",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Receptor"
] | [
"Cancer-related genes"
] | [
"Plasma membrane"
] | [
"Nucleoli"
] | [] | [] | Approved | null | null | 17 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 48: Non-specific - Mixed function | Cluster 21: Lymphoma - Adaptive immune response | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in many | 5 | 0 | 0 | 0 | [] | [] | [] | 654 | 1 |
ENSG00000049283 | EPN3 | Epsin 3 | [
"Q9H201"
] | 17 | 50532682-50543750 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA055546",
"HPA063224"
] | [
"FLJ20778",
"MGC129899"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 3 | null | null | null | Cluster 49: Hindbrain - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 655 | 9 |
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