ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000057935 | MTA3 | Metastasis associated 1 family member 3 | [
"Q9BTC8"
] | 2 | 42494569-42756947 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039433"
] | [
"KIAA1266"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Supported | Approved | null | 34 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 51: Neurons - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 80: Thymus - Adaptive immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 773 | 4 |
ENSG00000058056 | USP13 | Ubiquitin specific peptidase 13 | [
"Q92995"
] | 3 | 179653032-179804366 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004827"
] | [
"IsoT-3"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Autophagy",
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 45 | null | null | Cluster 1: T-cells - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 30: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in all | 9 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 774 | 9 |
ENSG00000058063 | ATP11B | ATPase phospholipid transporting 11B (putative) | [
"Q9Y2G3"
] | 3 | 182793503-182921629 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036237",
"HPA036238"
] | [
"ATPIF",
"ATPIR",
"KIAA0956"
] | [
"Enzymes",
"Predicted membrane proteins",
"Transporters"
] | [
"Lipid transport",
"Transport"
] | [
"Translocase"
] | [] | [
"Centriolar satellite",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 4 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 63: Non-specific - Protein processing | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in all | 4 | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 775 | 7 |
ENSG00000058085 | LAMC2 | Laminin subunit gamma 2 | [
"Q13753"
] | 1 | 183186238-183245127 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004257",
"HPA024638",
"HPA046539",
"HPA046540",
"CAB078165"
] | [
"BM600-100kDa",
"EBR2",
"EBR2A",
"kalinin-105kDa",
"LAMB2T",
"LAMNB2",
"nicein-100kDa"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [
"Heparin-binding"
] | [
"Epidermolysis bullosa"
] | [
"Endoplasmic reticulum",
"Golgi apparatus"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Cell adhesion"
] | Approved | Enhanced | null | 4 | No | No | null | Cluster 15: Non-specific - Transcription | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 13: Lung - Secretion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in many | 6 | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 776 | 6 |
ENSG00000058091 | CDK14 | Cyclin dependent kinase 14 | [
"O94921"
] | 7 | 90466424-91210590 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015267"
] | [
"PFTAIRE1",
"PFTK1"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Wnt signaling pathway"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 27 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 46: Lymphoma - Humoral immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 27: Cerebellum - Synaptic function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 8 | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Stomach Adenocarcinoma"
] | 777 | 6 |
ENSG00000058262 | SEC61A1 | SEC61 translocon subunit alpha 1 | [
"P61619"
] | 3 | 128051641-128071705 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022076"
] | [] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Protein transport",
"Translocation",
"Transport"
] | [
"Chaperone"
] | [
"Disease variant"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | null | null | 63 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 44: Non-specific - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 8: Non-specific - Secretory pathway | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 778 | 5 |
ENSG00000058335 | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1 | [
"Q13972"
] | 15 | 78959906-79090780 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010413",
"HPA041965"
] | [
"CDC25",
"CDC25L",
"GNRP",
"GRF1",
"GRF55",
"H-GRF55",
"PP13187"
] | [
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Approved | null | 2 | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 70: DU4475 - Unknown function | Cluster 80: Oligodendrocytes - Myelination | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in some | 7 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Lung Squamous Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | 780 | 6 |
ENSG00000058404 | CAMK2B | Calcium/calmodulin dependent protein kinase II beta | [
"Q13554"
] | 7 | 44210019-44334577 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB006849",
"HPA026307",
"HPA051783",
"HPA051785",
"HPA053973"
] | [
"CAM2",
"CAMK2",
"CAMKB",
"CaMKIIbeta"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Actin-binding",
"Calmodulin-binding",
"Developmental protein",
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Intellectual disability"
] | [
"Plasma membrane",
"Primary cilium tip",
"Primary cilium transition zone",
"Principal piece"
] | [
"Cell Junctions",
"Perinuclear theca",
"Calyx",
"Connecting piece",
"End piece"
] | [] | [] | Approved | Enhanced | Supported | 33 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 25: Non-specific - Basic cellular processes | Group enriched | Detected in many | 6 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 781 | 6 |
ENSG00000058453 | CROCC | Ciliary rootlet coiled-coil, rootletin | [
"Q5TZA2"
] | 1 | 16740273-16972964 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021191",
"HPA021762"
] | [
"CROCC1",
"ROLT",
"rootletin"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cilium biogenesis/degradation"
] | [] | [] | [
"Centrosome",
"Basal body"
] | [
"Plasma membrane",
"Primary cilium transition zone",
"Mid piece"
] | [] | [] | Supported | Enhanced | null | 5 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 65: Non-specific - Cell growth & division | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 782 | 5 |
ENSG00000058600 | POLR3E | RNA polymerase III subunit E | [
"Q9NVU0"
] | 16 | 22297375-22335101 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041419",
"HPA041477"
] | [
"C37",
"FLJ10509",
"RPC5",
"SIN"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins",
"RNA polymerase related proteins"
] | [
"Antiviral defense",
"Immunity",
"Innate immunity",
"Transcription"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 99 | Yes | No | Cluster 16: Non-specific - Cell proliferation | Cluster 44: Non-specific - Mixed function | Cluster 54: Non-specific - Transcription | Cluster 102: Non-specific - Mixed function | Cluster 24: Non-specific - Transcription | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 783 | 7 |
ENSG00000058668 | ATP2B4 | ATPase plasma membrane Ca2+ transporting 4 | [
"P23634"
] | 1 | 203626832-203744081 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016118",
"HPA040431"
] | [
"ATP2B2",
"MXRA1",
"PMCA4"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calmodulin-binding",
"Translocase"
] | [
"FDA approved drug targets"
] | [
"Plasma membrane",
"Primary cilium"
] | [
"Mitochondria",
"Basal body"
] | [] | [] | Supported | Enhanced | null | 19 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 51: Neurons - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 26: Keratinocytes - Keratinization | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in all | null | Cancer enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 784 | 4 |
ENSG00000058673 | ZC3H11A | Zinc finger CCCH-type containing 11A | [
"O75152"
] | 1 | 203795623-203854999 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026439",
"HPA028490",
"HPA028526"
] | [
"KIAA0663",
"ZC3HDC11A"
] | [
"Predicted intracellular proteins"
] | [
"mRNA transport",
"Transport"
] | [] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | Approved | null | 47 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 6: Non-specific - Immune response | Cluster 71: Lymphoma - Inflammatory response | Cluster 22: Non-specific - Basic cellular functions | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in some | 13 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 785 | 8 |
ENSG00000058729 | RIOK2 | RIO kinase 2 | [
"Q9BVS4"
] | 5 | 97160867-97183247 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA005681"
] | [
"FLJ11159"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Ribosome biogenesis"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Uncertain | null | 29 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 55: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 786 | 5 |
ENSG00000058799 | YIPF1 | Yip1 domain family member 1 | [
"Q9Y548"
] | 1 | 53851719-53889798 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014716",
"HPA073931"
] | [
"DJ167A19.1",
"FinGER1"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | Supported | Approved | null | 36 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 21: Non-specific - Metabolism | Cluster 27: Breast cancer - Unknown function | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma"
] | 787 | 2 |
ENSG00000058804 | NDC1 | NDC1 transmembrane nucleoporin | [
"Q9BTX1"
] | 1 | 53765478-53838463 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA069751",
"HPA070882"
] | [
"FLJ10407",
"NET3",
"TMEM48"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"mRNA transport",
"Protein transport",
"Translocation",
"Transport"
] | [] | [] | [
"Nuclear membrane"
] | [
"Plasma membrane",
"Actin filaments"
] | [] | [] | Supported | Approved | null | 18 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 55: Non-specific - Transcription | Cluster 37: Non-specific - mRNA processing | Cluster 27: Non-specific - Cell proliferation | Cluster 34: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 5 | 0 | 5 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 788 | 9 |
ENSG00000058866 | DGKG | Diacylglycerol kinase gamma | [
"P49619"
] | 3 | 186105668-186362234 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036577"
] | [
"DAGK3"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Kinase",
"Transferase"
] | [] | [
"Vesicles",
"Plasma membrane"
] | [] | [] | [] | Approved | Approved | null | 4 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 37: Neurons - Mixed function | Cluster 11: Neuronal - Sensory perception | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 6 | 0 | 0 | 0 | [] | [] | [] | 789 | 7 |
ENSG00000059122 | FLYWCH1 | FLYWCH-type zinc finger 1 | [
"Q4VC44"
] | 16 | 2911931-2951208 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040753",
"HPA041001"
] | [
"DKFZp761A132"
] | [
"Predicted intracellular proteins"
] | [
"DNA damage",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Cytosol"
] | [] | [] | Enhanced | Approved | null | 9 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 45: Non-specific - Mixed function | Cluster 54: Non-specific - Transcription | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 790 | 5 |
ENSG00000059145 | UNKL | Unk like zinc finger | [
"Q9H9P5"
] | 16 | 1363205-1414751 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055801",
"HPA073949"
] | [
"C16orf28",
"FLJ23360",
"ZC3H5L",
"ZC3HDC5L"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 7 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 6: Non-specific - Immune response | Cluster 54: Non-specific - Transcription | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 791 | 6 |
ENSG00000059377 | TBXAS1 | Thromboxane A synthase 1 | [
"P24557"
] | 7 | 139777051-140020325 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031257",
"HPA031258",
"HPA031259"
] | [
"CYP5",
"CYP5A1",
"THAS",
"TS",
"TXAS",
"TXS"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Fatty acid biosynthesis",
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid metabolism",
"Prostaglandin biosynthesis",
"Prostaglandin metabolism"
] | [
"Isomerase",
"Lyase",
"Monooxygenase",
"Oxidoreductase"
] | [
"Disease variant"
] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 1 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 14 | 1 | 0 | 1 | [] | [
"Testicular Germ Cell Tumor"
] | [
"Testicular Germ Cell Tumor"
] | 792 | 4 |
ENSG00000059588 | TARBP1 | TAR (HIV-1) RNA binding protein 1 | [
"Q13395"
] | 1 | 234391313-234479179 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB020810",
"HPA024632"
] | [
"TRM3",
"TRMT3",
"TRP-185"
] | [
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [
"Methyltransferase",
"RNA-binding",
"Transferase",
"tRNA-binding"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | Uncertain | null | 2 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 9: Non-specific - Receptor signaling | Cluster 45: Non-specific - Nuclear processes | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme"
] | 795 | 4 |
ENSG00000059691 | GATB | Glutamyl-tRNA amidotransferase subunit B | [
"O75879"
] | 4 | 151670504-151761007 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042610"
] | [
"PET112",
"PET112L"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Ligase"
] | [
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Uncertain | null | 19 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 27: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 7 | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 796 | 1 |
ENSG00000059728 | MXD1 | MAX dimerization protein 1 | [
"Q05195"
] | 2 | 69897688-69942945 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001599"
] | [
"bHLHc58",
"MAD",
"MAD1"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm",
"Mitochondria"
] | [
"Cytosol"
] | [] | [] | Uncertain | Enhanced | null | 9 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 16: Non-specific - Transcription | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 7 | Immune cell enriched | Detected in all | 4 | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 797 | 5 |
ENSG00000059769 | DNAJC25 | DnaJ heat shock protein family (Hsp40) member C25 | [
"Q9H1X3"
] | 9 | 111631334-111654351 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019122"
] | [
"bA16L21.2.1"
] | [
"Predicted membrane proteins"
] | [] | [
"Chaperone"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 11 | null | null | null | Cluster 17: Choroid plexus - Cilium | Cluster 43: Non-specific - Basic cellular processes | Cluster 22: Non-specific - Basic cellular functions | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 6 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 799 | 7 |
ENSG00000059804 | SLC2A3 | Solute carrier family 2 member 3 | [
"P11169"
] | 12 | 7919230-7936187 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002763",
"HPA006539"
] | [
"GLUT3"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Sugar transport",
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Approved | null | 3 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 1: Neurons - Mixed function | Cluster 34: Testis cancer - Unknown function | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in all | null | Cancer enriched | Detected in many | 7 | Cancer enriched | Detected in all | 5 | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 7 | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Stomach Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Stomach Adenocarcinoma"
] | 800 | 4 |
ENSG00000059915 | PSD | Pleckstrin and Sec7 domain containing | [
"A5PKW4"
] | 10 | 102402617-102421539 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA059237"
] | [
"EFA6",
"EFA6A",
"KIAA2011",
"PSD1",
"TYL"
] | [
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | 801 | 7 |
ENSG00000060069 | CTDP1 | CTD phosphatase subunit 1 | [
"Q9Y5B0"
] | 18 | 79679803-79754503 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB032641",
"HPA040394",
"HPA070389"
] | [
"FCP1"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [
"Hydrolase",
"Protein phosphatase"
] | [
"Cataract",
"Neuropathy"
] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Approved | Approved | null | 32 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 18: Non-specific - Mixed function | Cluster 13: Non-specific - Mixed function | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 47: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 802 | 4 |
ENSG00000060138 | YBX3 | Y-box binding protein 3 | [
"P16989"
] | 12 | 10699089-10723323 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034838"
] | [
"CSDA",
"CSDA1",
"dbpA",
"ZONAB"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 30 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 38: Non-specific - Transcription | Cluster 103: Non-specific - Basic cellular processes | Cluster 19: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in all | 7 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 5 | 0 | 5 | [
"Rectum Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 803 | 7 |
ENSG00000060140 | STYK1 | Serine/threonine/tyrosine kinase 1 | [
"Q6J9G0"
] | 12 | 10618923-10674318 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040468",
"HPA048569"
] | [
"DKFZp761P1010",
"NOK",
"SuRTK106"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Proto-oncogene"
] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Enhanced | null | 20 | null | null | Cluster 15: NK-cells - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 7 | 2 | 0 | 2 | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 804 | 3 |
ENSG00000060339 | CCAR1 | Cell division cycle and apoptosis regulator 1 | [
"Q8IX12"
] | 10 | 68721012-68792377 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007856",
"HPA048513"
] | [
"CARP-1",
"CARP1",
"FLJ10590"
] | [
"Cancer-related genes",
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Cell cycle",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Repressor"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Golgi apparatus"
] | [] | [] | Supported | Supported | null | 44 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 6: Non-specific - Immune response | Cluster 52: Non-specific - Mitochondria | Cluster 17: Non-specific - RNA processing | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Prostate Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Prostate Adenocarcinoma"
] | 806 | 1 |
ENSG00000060491 | OGFR | Opioid growth factor receptor | [
"Q9NZT2"
] | 20 | 62804835-62814000 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017899"
] | [
"7-60"
] | [
"Predicted intracellular proteins"
] | [
"Growth regulation"
] | [
"Receptor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Supported | null | 2 | null | null | Cluster 19: Eosinophils - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Group enriched | Detected in many | 4 | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 807 | 5 |
ENSG00000060642 | PIGV | Phosphatidylinositol glycan anchor biosynthesis class V | [
"Q9NUD9"
] | 1 | 26787054-26800659 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA054181"
] | [
"FLJ20477"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"GPI-anchor biosynthesis"
] | [
"Glycosyltransferase",
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Cytosol"
] | [
"Endoplasmic reticulum"
] | [] | [] | Approved | null | null | 3 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 21: Non-specific - Metabolism | Cluster 37: Non-specific - mRNA processing | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 810 | 9 |
ENSG00000060656 | PTPRU | Protein tyrosine phosphatase receptor type U | [
"Q92729"
] | 1 | 29236516-29326813 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB011476",
"HPA039832"
] | [
"FMI",
"hPTP-J",
"PCP-2",
"PTP",
"PTPRO"
] | [
"Enzymes",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Differentiation"
] | [
"Hydrolase",
"Protein phosphatase",
"Receptor"
] | [] | [] | [] | [] | [] | null | Approved | null | 4 | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 811 | 9 |
ENSG00000060688 | SNRNP40 | Small nuclear ribonucleoprotein U5 subunit 40 | [
"Q96DI7"
] | 1 | 31259568-31296788 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026527",
"HPA027345"
] | [
"HPRP8BP",
"PRP8BP",
"PRPF8BP",
"SPF38",
"WDR57"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Supported | null | 184 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 17: Non-specific - RNA processing | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 812 | 8 |
ENSG00000060709 | RIMBP2 | RIMS binding protein 2 | [
"O15034"
] | 12 | 130396133-130768228 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041494",
"HPA044114"
] | [
"KIAA0318",
"MGC15831",
"PPP1R133",
"RBP2",
"RIM-BP2"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Golgi apparatus",
"Cytosol"
] | [] | [] | Approved | null | null | null | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 6 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 813 | 3 |
ENSG00000060718 | COL11A1 | Collagen type XI alpha 1 chain | [
"P12107"
] | 1 | 102876467-103108872 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA058335"
] | [
"CO11A1",
"COLL6",
"DFNA37",
"STL2"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [
"Cancer-related genes",
"Cataract",
"Deafness",
"Disease variant",
"Dwarfism",
"Ectodermal dysplasia",
"Non-syndromic deafness",
"Stickler syndrome"
] | [
"Endoplasmic reticulum"
] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | Supported | null | null | null | No | No | null | Cluster 53: Neurons - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 814 | 8 |
ENSG00000060749 | QSER1 | Glutamine and serine rich 1 | [] | 11 | 32892811-32993316 | Evidence at transcript level | Evidence at transcript level | null | null | [
"HPA005682"
] | [
"FLJ21924"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 7 | null | null | null | Cluster 25: Non-specific - Transcription | Cluster 24: Non-specific - Unknown function | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 55: Breast - Lactation | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Not detected in immune cells | Not detected | null | 7 | 0 | 7 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 815 | 7 |
ENSG00000060762 | MPC1 | Mitochondrial pyruvate carrier 1 | [
"Q9Y5U8"
] | 6 | 166364919-166383013 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045119",
"HPA055790"
] | [
"BRP44L",
"CGI-129",
"dJ68L15.3",
"SLC54A1"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [
"Disease variant"
] | [
"Mitochondria"
] | [
"Principal piece"
] | [] | [] | Enhanced | Enhanced | null | 3 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 28: Non-specific - Nuclear processes | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 816 | 9 |
ENSG00000060982 | BCAT1 | Branched chain amino acid transaminase 1 | [
"P54687"
] | 12 | 24810024-24949101 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048592"
] | [
"BCATc",
"BCT1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Amino-acid biosynthesis",
"Branched-chain amino acid biosynthesis",
"Lipid metabolism"
] | [
"Aminotransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 45: Non-specific - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 8: Pancreas - Proteolysis | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 3 | 0 | 3 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 818 | 4 |
ENSG00000061273 | HDAC7 | Histone deacetylase 7 | [
"Q8WUI4"
] | 12 | 47782722-47833132 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004775",
"CAB080431"
] | [
"DKFZP586J0917",
"HDAC7A"
] | [
"Enzymes",
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Hydrolase",
"Repressor"
] | [
"FDA approved drug targets"
] | [
"Cytosol"
] | [] | [] | [] | Enhanced | null | null | 39 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 15: Kidney cancer - Membrane components | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Immune cell enriched | Detected in some | 4 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 819 | 5 |
ENSG00000061337 | LZTS1 | Leucine zipper tumor suppressor 1 | [
"Q9Y250"
] | 8 | 20246165-20303963 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA006294",
"HPA022046"
] | [
"FEZ1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [] | [
"Tumor suppressor"
] | [
"Plasma membrane"
] | [
"Nucleoli"
] | [] | [] | Approved | Approved | null | 79 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 110: Mural cells - ECM organization | Cluster 73: Brain - Neuronal signaling | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 820 | 1 |
ENSG00000061455 | PRDM6 | PR/SET domain 6 | [
"Q9NQX0"
] | 5 | 123089241-123194266 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030324"
] | [
"KMT8C",
"PRISM"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Methyltransferase",
"Repressor",
"Transferase"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 49 | null | null | null | Cluster 45: Non-specific - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 821 | 4 |
ENSG00000061492 | WNT8A | Wnt family member 8A | [
"Q9H1J5"
] | 5 | 138083990-138092365 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038539"
] | [
"WNT8D"
] | [
"Predicted secreted proteins"
] | [
"Wnt signaling pathway"
] | [
"Developmental protein"
] | [] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Developmental protein"
] | null | Uncertain | null | null | null | null | null | Cluster 32: Cerebral cortex - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 35: Neurons - Synaptic function & neurogenesis | null | Not detected | Not detected | null | Cancer enriched | Detected in single | 5 | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 822 | 5 |
ENSG00000061676 | NCKAP1 | NCK associated protein 1 | [
"Q9Y2A7"
] | 2 | 182909115-183038858 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020449"
] | [
"HEM2",
"Nap1",
"NAP125"
] | [
"Predicted membrane proteins"
] | [
"Host-virus interaction"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 94 | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 824 | 2 |
ENSG00000061794 | MRPS35 | Mitochondrial ribosomal protein S35 | [
"P82673"
] | 12 | 27710822-27756295 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038513"
] | [
"MDS023",
"MRPS28"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [
"Mitochondria"
] | [
"Cytosol",
"Connecting piece"
] | [] | [] | Supported | Supported | null | 87 | No | No | Cluster 33: Non-specific - ATP binding | Cluster 21: Non-specific - Metabolism | Cluster 10: Ciliated cells - Ion channel activity | Cluster 97: Non-specific - Cellular respiration | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 6 | 2 | 5 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 825 | 8 |
ENSG00000061918 | GUCY1B1 | Guanylate cyclase 1 soluble subunit beta 1 | [
"Q02153"
] | 4 | 155758992-155807811 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010890",
"HPA020870",
"HPA077706"
] | [
"GC-S-beta-1",
"GC-SB3",
"GUC1B3",
"GUCY1B3"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"cGMP biosynthesis"
] | [
"Lyase"
] | [
"FDA approved drug targets"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 6 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 14: Neurons - Synaptic function | Cluster 55: Lymphoma - Immune response | Cluster 110: Mural cells - ECM organization | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 8 | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 826 | 1 |
ENSG00000061936 | SFSWAP | Splicing factor SWAP | [
"Q12872"
] | 12 | 131711081-131799738 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039362",
"HPA040063"
] | [
"SFRS8",
"SWAP"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing",
"Transcription",
"Transcription regulation"
] | [
"Repressor",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | Approved | Approved | null | 14 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 38: Non-specific - Transcription | Cluster 7: Non-specific - Transcription | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 827 | 1 |
ENSG00000061938 | TNK2 | Tyrosine kinase non receptor 2 | [
"Q07912"
] | 3 | 195863364-195911945 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041954",
"HPA069561"
] | [
"ACK",
"ACK1",
"p21cdc42Hs"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Endocytosis"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes"
] | [
"Plasma membrane"
] | [
"Vesicles"
] | [] | [] | Supported | Approved | null | 56 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 32: Cerebral cortex - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 78: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme"
] | 828 | 1 |
ENSG00000061987 | MON2 | MON2 homolog, regulator of endosome-to-Golgi trafficking | [
"Q7Z3U7"
] | 12 | 62466817-62600476 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038697",
"HPA057607"
] | [
"KIAA1040"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Nucleoplasm",
"Nucleoli fibrillar center"
] | [] | [] | [] | Approved | Uncertain | null | 8 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 829 | 3 |
ENSG00000062038 | CDH3 | Cadherin 3 | [
"P22223"
] | 16 | 68636189-68727468 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001767",
"CAB002487",
"HPA002974"
] | [
"CDHP",
"PCAD"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Sensory transduction",
"Vision"
] | [] | [
"Disease variant",
"Ectodermal dysplasia",
"Hypotrichosis"
] | [
"Plasma membrane",
"Cell Junctions"
] | [] | [] | [] | Supported | Enhanced | null | 5 | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 26: Keratinocytes - Keratinization | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 830 | 4 |
ENSG00000062096 | ARSF | Arylsulfatase F | [
"P54793"
] | X | 3041471-3112727 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000549"
] | [
"ASF"
] | [
"Enzymes",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase"
] | [] | [
"Vesicles",
"Cytosol"
] | [] | [
"Secreted in other tissues"
] | [
"Enzyme"
] | Approved | null | null | 2 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 831 | 2 |
ENSG00000062194 | GPBP1 | GC-rich promoter binding protein 1 | [
"Q86WP2"
] | 5 | 57173948-57264679 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037773"
] | [
"DKFZp761C169"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Vesicles",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Approved | null | 15 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 55: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 832 | 2 |
ENSG00000062282 | DGAT2 | Diacylglycerol O-acyltransferase 2 | [
"Q96PD7"
] | 11 | 75759512-75801535 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA013351"
] | [] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Glycerol metabolism",
"Lipid biosynthesis",
"Lipid metabolism"
] | [
"Acyltransferase",
"Transferase"
] | [
"FDA approved drug targets"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Approved | null | null | null | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 33: Neurons - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 45: Liver - Metabolism & Coagulation | Group enriched | Detected in many | 7 | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 11 | 2 | 0 | 2 | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 833 | 6 |
ENSG00000062370 | ZNF112 | Zinc finger protein 112 | [
"Q9UJU3"
] | 19 | 44326555-44367217 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023856",
"HPA076887"
] | [
"ZFP112",
"ZNF228"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli fibrillar center"
] | [] | [] | Supported | Approved | null | null | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 25: Non-specific - Transcription | Cluster 4: Non-specific - Transcription | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 834 | 1 |
ENSG00000062485 | CS | Citrate synthase | [
"O75390"
] | 12 | 56271699-56300391 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038460",
"HPA038461",
"CAB075750",
"CAB075751",
"CAB075752",
"CAB075753",
"CAB075754"
] | [] | [
"Citric acid cycle related proteins",
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Tricarboxylic acid cycle"
] | [
"Transferase"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Enhanced | null | 190 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 38: Non-specific - Transcription | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 41: Striated muscle - Muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 835 | 7 |
ENSG00000062524 | LTK | Leukocyte receptor tyrosine kinase | [
"P29376"
] | 15 | 41503637-41513887 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA059545"
] | [
"TYK1"
] | [
"Disease related genes",
"Enzymes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Kinase",
"Receptor",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Systemic lupus erythematosus"
] | [
"Vesicles"
] | [] | [] | [] | Approved | null | null | 37 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 35: RS4;11 - Unknown function | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in some | 5 | 0 | 0 | 0 | [] | [] | [] | 836 | 1 |
ENSG00000062598 | ELMO2 | Engulfment and cell motility 2 | [
"Q96JJ3"
] | 20 | 46366050-46432985 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018811"
] | [
"CED-12",
"CED12",
"ELMO-2",
"FLJ11656",
"KIAA1834"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Phagocytosis"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 10 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 15: Non-specific - Transcription | Cluster 62: Non-specific - Plasma proteins | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 27: Cerebellum - Synaptic function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 838 | 8 |
ENSG00000062650 | WAPL | WAPL cohesin release factor | [
"Q7Z5K2"
] | 10 | 86435256-86521792 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037874",
"HPA037875",
"HPA066141"
] | [
"FOE",
"KIAA0261",
"WAPAL"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Host-virus interaction",
"Mitosis"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 42 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 55: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 17: Non-specific - RNA processing | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 839 | 8 |
ENSG00000062716 | VMP1 | Vacuole membrane protein 1 | [
"Q96GC9"
] | 17 | 59707192-59842255 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030773",
"HPA064780"
] | [
"EPG3",
"TANGO5",
"TMEM49"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Autophagy",
"Cell adhesion",
"Lipid transport",
"Transport"
] | [] | [] | [
"Endoplasmic reticulum"
] | [
"Nucleoli"
] | [] | [] | Approved | Approved | null | 23 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 28: Liver & Adrenal gland - Secretion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 4 | Immune cell enriched | Detected in all | 5 | 3 | 0 | 3 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 840 | 4 |
ENSG00000062725 | APPBP2 | Amyloid beta precursor protein binding protein 2 | [
"Q92624"
] | 17 | 60443158-60526242 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA066852",
"HPA078370"
] | [
"Hs.84084",
"KIAA0228",
"PAT1"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport",
"Ubl conjugation pathway"
] | [] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 109 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 841 | 3 |
ENSG00000062822 | POLD1 | DNA polymerase delta 1, catalytic subunit | [
"P28340"
] | 19 | 50384204-50418018 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004375",
"HPA046524"
] | [
"CDC2",
"POLD"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA excision",
"DNA repair",
"DNA replication"
] | [
"DNA-binding",
"DNA-directed DNA polymerase",
"Exonuclease",
"Hydrolase",
"Nuclease",
"Nucleotidyltransferase",
"Transferase"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Supported | null | 71 | null | null | Cluster 18: Non-specific - Translation | Cluster 6: Non-specific - Immune response | Cluster 4: Non-specific - Transcription | Cluster 27: Non-specific - Cell proliferation | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 842 | 7 |
ENSG00000063015 | SEZ6 | Seizure related 6 homolog | [
"Q53EL9"
] | 17 | 28954901-29006440 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011777"
] | [] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 1 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 11 | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 5 | 0 | 0 | 0 | [] | [] | [] | 843 | 2 |
ENSG00000063046 | EIF4B | Eukaryotic translation initiation factor 4B | [
"P23588"
] | 12 | 53006282-53042215 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039072",
"HPA046164"
] | [] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Initiation factor",
"RNA-binding"
] | [] | [
"Endoplasmic reticulum",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Approved | null | 73 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 844 | 6 |
ENSG00000063169 | BICRA | BRD4 interacting chromatin remodeling complex associated protein | [
"Q9NZM4"
] | 19 | 47608196-47703277 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA056211"
] | [
"GLTSCR1",
"SMARCK1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 21 | null | null | null | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 4: Non-specific - Transcription | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Rectum Adenocarcinoma"
] | 846 | 2 |
ENSG00000063176 | SPHK2 | Sphingosine kinase 2 | [
"Q9NRA0"
] | 19 | 48619291-48630717 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049062"
] | [] | [
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 4 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 45: Non-specific - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 847 | 4 |
ENSG00000063180 | CA11 | Carbonic anhydrase 11 | [
"O75493"
] | 19 | 48637946-48646187 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041778"
] | [
"CARP2",
"CARPX1"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Vesicles",
"Microtubules"
] | [] | [
"Secreted in brain"
] | [
"No annotated function"
] | Approved | null | null | 2 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 53: Neurons - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in all | 10 | Cancer enriched | Detected in many | 4 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 849 | 6 |
ENSG00000063241 | ISOC2 | Isochorismatase domain containing 2 | [
"Q96AB3"
] | 19 | 55452985-55462343 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043142"
] | [
"FLJ23469"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 1 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 4: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 850 | 7 |
ENSG00000063245 | EPN1 | Epsin 1 | [
"Q9Y6I3"
] | 19 | 55675226-55709858 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB009729",
"HPA061136",
"HPA071503"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Endocytosis"
] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | Approved | Approved | null | 33 | No | No | Cluster 25: Non-specific - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 852 | 4 |
ENSG00000063322 | MED29 | Mediator complex subunit 29 | [
"Q9NX70"
] | 19 | 39391303-39400641 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055956"
] | [
"DKFZp434H247",
"IXL",
"MED2"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 154 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 19: Astrocytes - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 65: Non-specific - Cell growth & division | Cluster 78: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 853 | 4 |
ENSG00000063438 | AHRR | Aryl hydrocarbon receptor repressor | [] | 5 | 321714-438291 | Evidence at protein level | Evidence at protein level | null | null | [
"HPA021483"
] | [
"AHH",
"AHHR",
"bHLHe77",
"KIAA1234"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 1 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 49: HMC-1 - Innate immune response | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 47: Testis - Mixed function | Tissue enriched | Detected in many | 4 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 9 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 854 | 9 |
ENSG00000063515 | GSC2 | Goosecoid homeobox 2 | [
"O15499"
] | 22 | 19146993-19150292 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043011"
] | [
"GSCL"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"DNA-binding"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 46 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 1: Neuronal - Visual perception | Cluster 106: Spermatogonia - Spermatogonial differentiation | Cluster 47: Testis - Mixed function | Group enriched | Detected in some | 20 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in some | 10 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 855 | 6 |
ENSG00000063587 | ZNF275 | Zinc finger protein 275 | [
"Q9NSD4"
] | X | 153334147-153360110 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000566"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoli"
] | [] | [] | [] | Approved | Approved | null | 13 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 22: Non-specific - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 856 | 1 |
ENSG00000063601 | MTMR1 | Myotubularin related protein 1 | [
"Q13613"
] | X | 150692971-150765108 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018502",
"HPA075953"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 20 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 29: Forebrain - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 857 | 3 |
ENSG00000063660 | GPC1 | Glypican 1 | [
"P35052"
] | 2 | 240435663-240468076 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030571"
] | [
"glypican"
] | [
"Disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Supported | null | null | 32 | null | null | null | Cluster 32: Cerebral cortex - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 24: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 858 | 2 |
ENSG00000063761 | ADCK1 | AarF domain containing kinase 1 | [
"Q86TW2"
] | 14 | 77800109-77935014 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051012",
"HPA055014"
] | [
"FLJ39600"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Uncertain | Uncertain | null | null | null | null | Cluster 29: Non-specific - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 7: Non-specific - Transcription | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 859 | 1 |
ENSG00000063978 | RNF4 | Ring finger protein 4 | [
"P78317"
] | 4 | 2462220-2515857 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022047",
"HPA049356"
] | [
"RES4-26",
"SLX5",
"SNURF"
] | [
"Enzymes",
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway"
] | [
"Activator",
"DNA-binding",
"Transferase"
] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Microtubule ends"
] | [] | [] | Supported | Approved | null | 165 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 38: Sub-cortical - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 7: Non-specific - Transcription | Cluster 51: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 861 | 7 |
ENSG00000064012 | CASP8 | Caspase 8 | [
"Q14790"
] | 2 | 201233443-201361836 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001302",
"CAB002047",
"HPA005688"
] | [
"Casp-8",
"FLICE",
"MACH",
"MCH5"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Host-virus interaction"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Mitochondria",
"Cytosol"
] | [
"Centriolar satellite",
"Connecting piece",
"Mid piece",
"Principal piece"
] | [] | [] | Uncertain | Approved | null | 83 | null | No | Cluster 35: Neutrophils - Protein binding | Cluster 20: Macrophages & Microglia - Immune response | Cluster 51: Myeloma - Immunoglobulins | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 862 | 4 |
ENSG00000064042 | LIMCH1 | LIM and calponin homology domains 1 | [
"Q9UPQ0"
] | 4 | 41359607-41700044 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004184",
"HPA063840"
] | [
"DKFZP686A01247",
"LIMCH1A",
"LMO7B"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Actin filaments"
] | [] | [] | [] | Supported | Uncertain | null | 3 | null | null | null | Cluster 13: Oligodendrocytes - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 62: Skeletal muscle - Muscle contraction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 8 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 863 | 6 |
ENSG00000064102 | INTS13 | Integrator complex subunit 13 | [
"Q9NVM9"
] | 12 | 26905181-26938326 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039543",
"HPA040109",
"HPA073020"
] | [
"ASUN",
"C12orf11",
"FLJ10637",
"Mat89Bb",
"NET48",
"SPATA30"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Vesicles"
] | [] | [] | Supported | Uncertain | null | 18 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 30: White matter - Myelination | Cluster 38: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 864 | 6 |
ENSG00000064115 | TM7SF3 | Transmembrane 7 superfamily member 3 | [
"Q9NS93"
] | 12 | 26971579-27014434 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA057640"
] | [] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Stress response"
] | [] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | null | null | null | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 10: Ciliated cells - Ion channel activity | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 865 | 8 |
ENSG00000064199 | SPA17 | Sperm autoantigenic protein 17 | [
"Q15506"
] | 11 | 124673844-124697518 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037568"
] | [
"CT22",
"SP17"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus",
"Principal piece"
] | [
"Vesicles"
] | [] | [] | Approved | Enhanced | null | 13 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 3: Choroid plexus - Cilium | Cluster 10: Ciliated cells - Ion channel activity | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 867 | 6 |
ENSG00000064201 | TSPAN32 | Tetraspanin 32 | [
"Q96QS1"
] | 11 | 2301997-2318204 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA024135"
] | [
"PHEMX",
"TSSC6"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 15: Bone marrow - Innate immune response | Group enriched | Detected in some | 6 | Cancer enriched | Detected in some | 6 | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 868 | 4 |
ENSG00000064205 | CCN5 | Cellular communication network factor 5 | [
"O76076"
] | 20 | 44714844-44728509 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB019273",
"HPA072121"
] | [
"CT58",
"CTGF-L",
"WISP-2",
"WISP2"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Plasma membrane"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Cell adhesion"
] | Approved | Approved | null | 1 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 869 | 9 |
ENSG00000064218 | DMRT3 | Doublesex and mab-3 related transcription factor 3 | [
"Q9NQL9"
] | 9 | 976655-991732 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA077685"
] | [
"DMRTA3"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Sexual differentiation",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [] | [] | [] | [] | [] | null | Approved | null | 66 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 69: Parathyroid gland - Mixed function | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Uterine Corpus Endometrial Carcinoma"
] | [
"Uterine Corpus Endometrial Carcinoma"
] | 870 | 1 |
ENSG00000064225 | ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | [
"Q9Y274"
] | 3 | 98732236-98821201 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018792"
] | [
"SIAT10",
"ST3GALVI"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 43: Hindbrain - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 57: Podocytes - Glomerular filtration | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 871 | 2 |
ENSG00000064270 | ATP2C2 | ATPase secretory pathway Ca2+ transporting 2 | [
"O75185"
] | 16 | 84368527-84464187 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA052262",
"HPA075812"
] | [
"KIAA0703",
"SPCA2"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Translocase"
] | [
"FDA approved drug targets"
] | [
"Plasma membrane",
"Focal adhesion sites"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 872 | 2 |
ENSG00000064300 | NGFR | Nerve growth factor receptor | [
"P08138"
] | 17 | 49495293-49515008 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000143",
"CAB001995",
"HPA004765"
] | [
"CD271",
"p75NTR",
"TNFRSF16"
] | [
"Cancer-related genes",
"CD markers",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"RAS pathway related proteins",
"Transporters"
] | [
"Apoptosis",
"Biological rhythms",
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein",
"Receptor"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | [] | Approved | Enhanced | null | 35 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 69: Skin cancer - ECM organization | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 8 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 873 | 5 |
ENSG00000064309 | CDON | Cell adhesion associated, oncogene regulated | [
"Q4KMG0"
] | 11 | 125955796-126063335 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB012422",
"HPA017377"
] | [
"CDO",
"CDON1",
"Ihog",
"ORCAM"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [] | [
"Disease variant",
"Holoprosencephaly"
] | [] | [] | [] | [] | null | Uncertain | null | 2 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 33: Sarcoma - Muscle contraction | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 874 | 3 |
ENSG00000064313 | TAF2 | TATA-box binding protein associated factor 2 | [
"Q6P1X5"
] | 8 | 119730774-119832863 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CIF150",
"TAF2B",
"TAFII150"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [
"Disease variant",
"Intellectual disability"
] | [] | [] | [] | [] | null | null | null | 12 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 25: Non-specific - Transcription | Cluster 40: Non-specific - Unknown function | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 875 | 8 |
ENSG00000064419 | TNPO3 | Transportin 3 | [
"Q9Y5L0"
] | 7 | 128954180-129055173 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039555",
"HPA072893"
] | [
"IPO12",
"LGMD1F",
"MTR10A",
"TRN-SR",
"TRN-SR2"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [
"Disease variant",
"Limb-girdle muscular dystrophy"
] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 46 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 39: Non-specific - Transcription | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 877 | 6 |
ENSG00000064489 | BORCS8-MEF2B | BORCS8-MEF2B readthrough | [] | 19 | 19145569-19192158 | Evidence at protein level | Evidence at protein level | null | null | [
"HPA004734"
] | [
"MEF2BNB-MEF2B"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Cell Junctions"
] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 19: Eosinophils - Unknown function | null | Cluster 25: Non-specific - Ribosome | Cluster 105: Non-specific - Mixed function | null | Not detected | Not detected | null | Low cancer specificity | Detected in some | null | Not detected | Not detected | null | Group enriched | Detected in some | 14 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 878 | 7 |
ENSG00000064490 | RFXANK | Regulatory factor X associated ankyrin containing protein | [
"O14593"
] | 19 | 19192229-19201869 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049157",
"HPA053330"
] | [
"ANKRA1",
"BLS",
"F14150_1",
"MGC138628",
"RFX-B"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Disease variant",
"SCID"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 76 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 879 | 3 |
ENSG00000064545 | TMEM161A | Transmembrane protein 161A | [
"Q9NX61"
] | 19 | 19119169-19138513 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043365"
] | [
"FLJ20422",
"FLJ39645"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 22 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 27: Non-specific - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 880 | 2 |
ENSG00000064547 | LPAR2 | Lysophosphatidic acid receptor 2 | [
"Q9HBW0"
] | 19 | 19623655-19628930 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019616"
] | [
"EDG-4",
"EDG4",
"LPA2"
] | [
"G-protein coupled receptors",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [] | [] | [] | [] | null | Approved | null | 84 | null | null | Cluster 39: T-cells - T-cell receptor | Cluster 20: Macrophages & Microglia - Immune response | Cluster 49: HMC-1 - Innate immune response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 881 | 9 |
ENSG00000064601 | CTSA | Cathepsin A | [
"P10619"
] | 20 | 45890144-45898949 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB024930",
"HPA031068",
"HPA072487"
] | [
"GSL",
"PPGB"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Carboxypeptidase",
"Hydrolase",
"Protease"
] | [
"Disease variant"
] | [
"Vesicles"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Enhanced | Enhanced | null | 13 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 21: Non-specific - Metabolism | Cluster 62: Non-specific - Plasma proteins | Cluster 47: Platelets - Hemostasis | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 6 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 882 | 8 |
ENSG00000064607 | SUGP2 | SURP and G-patch domain containing 2 | [
"Q8IX01"
] | 19 | 18990888-19034023 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041557",
"HPA061111"
] | [
"KIAA0365",
"SFRS14"
] | [
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Enhanced | Enhanced | null | 12 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 53: Neurons - Mixed function | Cluster 56: Non-specific - Sensory perception | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 883 | 2 |
ENSG00000064652 | SNX24 | Sorting nexin 24 | [
"Q9Y343"
] | 5 | 122843439-123029354 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044566",
"HPA073934"
] | [
"SBBI31"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 10 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 45: Non-specific - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 885 | 3 |
ENSG00000064655 | EYA2 | EYA transcriptional coactivator and phosphatase 2 | [
"O00167"
] | 20 | 46894624-47188844 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027024",
"HPA059291"
] | [
"EAB1"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Chromatin regulator",
"Developmental protein",
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 9 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 20: Myeloma - Immune response | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Thyroid Carcinoma"
] | [
"Thyroid Carcinoma"
] | 886 | 6 |
ENSG00000064666 | CNN2 | Calponin 2 | [
"Q99439"
] | 19 | 1026586-1039068 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049095",
"HPA075297"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding",
"Calmodulin-binding"
] | [] | [
"Actin filaments"
] | [] | [] | [] | Approved | Approved | null | 5 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 50: Non-specific - Nucleic acid binding | Cluster 55: Lymphoma - Immune response | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 887 | 8 |
ENSG00000064687 | ABCA7 | ATP binding cassette subfamily A member 7 | [
"Q8IZY2"
] | 19 | 1039997-1065572 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041564"
] | [
"ABCX"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Lipid transport",
"Phagocytosis",
"Transport"
] | [
"Translocase"
] | [
"Alzheimer disease",
"Amyloidosis",
"Neurodegeneration"
] | [
"Golgi apparatus",
"Plasma membrane"
] | [
"Cell Junctions"
] | [] | [] | Supported | Enhanced | null | null | null | null | Cluster 29: Non-specific - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 64: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 888 | 9 |
ENSG00000064726 | BTBD1 | BTB domain containing 1 | [
"Q9H0C5"
] | 15 | 83016423-83067252 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024263",
"HPA067671"
] | [] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Myogenesis",
"Ubl conjugation pathway"
] | [] | [] | [
"Cytoplasmic bodies"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 59 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 891 | 2 |
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