ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000138061 | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1 | [
"Q16678"
] | 2 | 38066973-38109902 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011705",
"HPA026863"
] | [
"CP1B",
"GLC3A"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism",
"Steroid metabolism"
] | [
"Lyase",
"Monooxygenase",
"Oxidoreductase"
] | [
"Disease variant",
"Glaucoma",
"Peters anomaly"
] | [
"Mitochondria"
] | [] | [] | [] | Uncertain | Approved | null | null | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 23: Choroid plexus - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 7 | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Stomach Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Stomach Adenocarcinoma"
] | 7,476 | 4 |
ENSG00000138068 | SULT6B1 | Sulfotransferase family 6B member 1 | [
"Q6IMI4"
] | 2 | 37167820-37196598 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [] | [] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Transferase"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in single | 5 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 4 | Immune cell enriched | Detected in single | 12 | 0 | 0 | 0 | [] | [] | [] | 7,477 | 6 |
ENSG00000138071 | ACTR2 | Actin related protein 2 | [
"P61160"
] | 2 | 65227788-65271253 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005083",
"HPA015050"
] | [
"ARP2"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [
"Cytosol"
] | [
"Nucleoli"
] | [] | [] | Uncertain | Approved | null | 125 | null | null | Cluster 41: Basophils - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 34: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 7,479 | 7 |
ENSG00000138073 | PREB | Prolactin regulatory element binding | [
"Q9HCU5"
] | 2 | 27130756-27134666 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA013582",
"HPA014133"
] | [
"SEC12"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"ER-Golgi transport",
"Protein transport",
"Transcription",
"Transcription regulation",
"Transport"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Uncertain | null | 30 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 45: Non-specific - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 8: Non-specific - Secretory pathway | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 7,480 | 6 |
ENSG00000138074 | SLC5A6 | Solute carrier family 5 member 6 | [
"Q9Y289"
] | 2 | 27199587-27212958 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036958"
] | [
"SMVT"
] | [
"Disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Sodium transport",
"Symport",
"Transport"
] | [] | [
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Approved | null | 10 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 42: Choroid plexus - Mitochondria | Cluster 34: Testis cancer - Unknown function | Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func. | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,481 | 3 |
ENSG00000138075 | ABCG5 | ATP binding cassette subfamily G member 5 | [
"Q9H222"
] | 2 | 43812472-43838865 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"STSL"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Lipid transport",
"Transport"
] | [
"Translocase"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | null | null | null | null | null | null | null | Cluster 18: Liver cancer - Metabolism | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 26: Kidney & Intestine - Metabolism | Group enriched | Detected in some | 69 | Not detected | Not detected | null | Cancer enriched | Detected in single | 25 | Group enriched | Detected in some | 9 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 7,482 | 5 |
ENSG00000138078 | PREPL | Prolyl endopeptidase like | [
"Q4J6C6"
] | 2 | 44316281-44361862 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA063238"
] | [
"KIAA0436"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Congenital myasthenic syndrome",
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | 8 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 14: Neurons - Synaptic function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 27: Cerebellum - Synaptic function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,483 | 2 |
ENSG00000138079 | SLC3A1 | Solute carrier family 3 member 1 | [
"Q07837"
] | 2 | 44275458-44321494 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038360",
"HPA071102"
] | [
"ATR1",
"CSNU1",
"D2H",
"NBAT",
"RBAT"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Amino-acid transport",
"Transport"
] | [] | [
"Cystinuria",
"Disease variant"
] | [
"Mitochondria"
] | [
"Nuclear bodies"
] | [] | [] | Approved | Enhanced | null | 1 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 15: Kidney cancer - Membrane components | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 8 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 7,484 | 3 |
ENSG00000138080 | EMILIN1 | Elastin microfibril interfacer 1 | [
"Q9Y6C2"
] | 2 | 27078615-27086403 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002822"
] | [
"DKFZp586M121",
"EMILIN",
"gp115"
] | [
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Cell adhesion"
] | null | Supported | null | 22 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 39: Astrocytes - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 7,485 | 1 |
ENSG00000138081 | FBXO11 | F-box protein 11 | [
"Q86XK2"
] | 2 | 47789316-47906498 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002690"
] | [
"FBX11",
"UBR6"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | [] | Supported | null | null | 23 | null | null | Cluster 32: Basophils - Transcription | Cluster 16: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 20: Non-specific - Transcription regulation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,486 | 1 |
ENSG00000138083 | SIX3 | SIX homeobox 3 | [
"O95343"
] | 2 | 44941702-44946071 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA067988"
] | [
"HPE2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding",
"Repressor"
] | [
"Disease variant",
"Holoprosencephaly"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | null | 5 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 1: Neuronal - Visual perception | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 4 | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [] | [
"Uterine Corpus Endometrial Carcinoma"
] | [
"Uterine Corpus Endometrial Carcinoma"
] | 7,487 | 4 |
ENSG00000138085 | ATRAID | All-trans retinoic acid induced differentiation factor | [
"Q6UW56"
] | 2 | 27212041-27217178 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051353"
] | [
"APR3",
"C2orf28",
"HSPC013",
"p18"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Differentiation"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 3 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 8: Non-specific - Secretory pathway | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 7,488 | 9 |
ENSG00000138092 | CENPO | Centromere protein O | [
"Q9BU64"
] | 2 | 24793136-24822376 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046189"
] | [
"CENP-O",
"MGC11266"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Supported | null | null | 17 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 20: Macrophages & Microglia - Immune response | Cluster 27: Breast cancer - Unknown function | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 5 | 2 | 4 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,489 | 5 |
ENSG00000138095 | LRPPRC | Leucine rich pentatricopeptide repeat containing | [
"P42704"
] | 2 | 43886224-43996226 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB033786",
"HPA036408",
"HPA036409"
] | [
"GP130",
"LRP130",
"LSFC"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Autophagy",
"mRNA transport",
"Transcription",
"Transcription regulation",
"Transport"
] | [
"DNA-binding",
"RNA-binding"
] | [
"Disease variant",
"Leigh syndrome",
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [
"Acrosome",
"Mid piece",
"End piece"
] | [] | [] | Enhanced | Enhanced | null | 92 | No | No | Cluster 16: Non-specific - Cell proliferation | Cluster 23: Choroid plexus - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 7,490 | 7 |
ENSG00000138100 | TRIM54 | Tripartite motif containing 54 | [
"Q9BYV2"
] | 2 | 27282429-27307439 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019690"
] | [
"MURF",
"MURF-3",
"RNF30"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation"
] | [
"Developmental protein"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 162 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 55: Myocytes - Oxidative muscle function | Cluster 30: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in many | 14 | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in some | 4 | Immune cell enriched | Detected in single | 17 | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,491 | 1 |
ENSG00000138101 | DTNB | Dystrobrevin beta | [
"O60941"
] | 2 | 25377198-25673647 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047168",
"HPA061357"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Uncertain | null | 46 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 7,492 | 8 |
ENSG00000138107 | ACTR1A | Actin related protein 1A | [
"P61163"
] | 10 | 102461881-102502712 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB037193",
"HPA047443"
] | [
"ARP1",
"Arp1A"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Microtubules"
] | [
"Cytokinetic bridge",
"Primary cilium",
"Cytosol"
] | [] | [] | Uncertain | Approved | null | 93 | Yes | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 45: Non-specific - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,493 | 4 |
ENSG00000138109 | CYP2C9 | Cytochrome P450 family 2 subfamily C member 9 | [
"P11712"
] | 10 | 94938658-94990091 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015066",
"CAB016123",
"HPA074424"
] | [
"CYP2C10",
"P450IIC9"
] | [
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism",
"Steroid metabolism",
"Sterol metabolism"
] | [
"Monooxygenase",
"Oxidoreductase"
] | [] | [
"Vesicles"
] | [
"Plasma membrane"
] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Uncertain | Enhanced | null | 4 | null | null | null | null | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 19 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in some | 43 | Cell type enriched | Detected in some | 28 | Not detected in immune cells | Not detected | null | 2 | 4 | 0 | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,494 | 2 |
ENSG00000138111 | MFSD13A | Major facilitator superfamily domain containing 13A | [
"Q14CX5"
] | 10 | 102461395-102477045 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018031"
] | [
"bA18I14.8",
"C10orf77",
"FLJ22529",
"TMEM180"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Golgi apparatus",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 3 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 2: Non-specific - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 7,495 | 6 |
ENSG00000138115 | CYP2C8 | Cytochrome P450 family 2 subfamily C member 8 | [
"P10632"
] | 10 | 95036772-95069497 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA013547",
"HPA013970",
"HPA015066",
"HPA074424"
] | [
"CPC8"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism",
"Steroid metabolism"
] | [
"Monooxygenase",
"Oxidoreductase"
] | [] | [
"Vesicles"
] | [
"Plasma membrane"
] | [] | [] | Uncertain | Enhanced | null | 2 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 15: Kidney cancer - Membrane components | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 363 | Not detected | Not detected | null | Cancer enriched | Detected in some | 84 | Cell type enriched | Detected in many | 17 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,496 | 4 |
ENSG00000138119 | MYOF | Myoferlin | [
"Q9NZM1"
] | 10 | 93306429-93482334 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014245"
] | [
"FER1L3",
"KIAA1207"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Vesicles",
"Plasma membrane",
"Centriolar satellite"
] | [
"Primary cilium",
"Primary cilium tip",
"Basal body"
] | [] | [] | Supported | Enhanced | null | 5 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 8: Immune cells - Immune response | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,497 | 8 |
ENSG00000138131 | LOXL4 | Lysyl oxidase like 4 | [
"Q96JB6"
] | 10 | 98247690-98268194 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB033876",
"HPA037609"
] | [
"FLJ21889",
"LOXC"
] | [
"Predicted secreted proteins"
] | [] | [
"Oxidoreductase"
] | [] | [
"Vesicles"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Enzyme"
] | Approved | Approved | null | 72 | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 69: Skin cancer - ECM organization | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Cancer enriched | Detected in many | 4 | Cancer enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 7,498 | 8 |
ENSG00000138134 | STAMBPL1 | STAM binding protein like 1 | [
"Q96FJ0"
] | 10 | 88879734-88975153 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040202"
] | [
"ALMalpha",
"AMSH-FP",
"AMSH-LP",
"bA399O19.2",
"FLJ31524",
"KIAA1373"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Uncertain | null | 37 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 53: Neurons - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Breast Invasive Carcinoma"
] | [] | [
"Breast Invasive Carcinoma"
] | 7,499 | 8 |
ENSG00000138135 | CH25H | Cholesterol 25-hydroxylase | [
"O95992"
] | 10 | 89205629-89207317 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Lipid biosynthesis",
"Lipid metabolism",
"Steroid biosynthesis",
"Steroid metabolism",
"Sterol biosynthesis",
"Sterol metabolism"
] | [
"Monooxygenase",
"Oxidoreductase"
] | [] | [] | [] | [] | [] | null | null | null | 2 | null | null | null | Cluster 44: Non-specific - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 103: Non-specific - Basic cellular processes | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 4 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Liver Hepatocellular Carcinoma"
] | [
"Lung Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 7,500 | 4 |
ENSG00000138136 | LBX1 | Ladybird homeobox 1 | [
"P52954"
] | 10 | 101226994-101229463 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002016",
"HPA002086",
"CAB079927"
] | [
"HPX6",
"LBX1H"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Myogenesis",
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Nuclear bodies",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 20 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enriched | Detected in some | 19 | Cancer enhanced | Detected in some | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,501 | 1 |
ENSG00000138138 | ATAD1 | ATPase family AAA domain containing 1 | [
"Q8NBU5"
] | 10 | 87751512-87841361 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA037569"
] | [
"FLJ14600",
"Msp1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [
"Translocase"
] | [
"Disease variant"
] | [
"Nucleoli rim"
] | [
"Mitochondria"
] | [] | [] | Approved | Uncertain | null | 5 | null | null | Cluster 15: NK-cells - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 52: Non-specific - Mitochondria | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,502 | 2 |
ENSG00000138152 | BTBD16 | BTB domain containing 16 | [
"Q32M84"
] | 10 | 122271296-122338159 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040529",
"HPA057638"
] | [
"C10orf87",
"Em:AC061711.1",
"FLJ25359"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli"
] | [
"Cytosol"
] | [] | [] | Uncertain | Uncertain | null | null | Yes | null | null | Cluster 28: Oligodendrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 47: Testis - Mixed function | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in some | 8 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,503 | 2 |
ENSG00000138160 | KIF11 | Kinesin family member 11 | [
"P52732"
] | 10 | 92574105-92655395 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006916",
"HPA010093",
"HPA010568",
"CAB017617"
] | [
"Eg5",
"HKSP",
"KNSL1",
"TRIP5"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [
"Motor protein"
] | [
"Disease variant"
] | [
"Cytosol",
"Mid piece"
] | [
"Vesicles",
"Mitotic spindle",
"Basal body",
"Principal piece",
"End piece"
] | [] | [] | Supported | Enhanced | null | 16 | Yes | Yes | Cluster 16: Non-specific - Cell proliferation | Cluster 23: Choroid plexus - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 5 | 4 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,504 | 3 |
ENSG00000138161 | CUZD1 | CUB and zona pellucida like domains 1 | [
"Q86UP6"
] | 10 | 122832158-122846175 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA068479",
"HPA068660",
"HPA074117"
] | [
"ERG-1",
"UO-44"
] | [
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Cell cycle",
"Cell division"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | No | null | null | Cluster 13: Non-specific - Mixed function | Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion | Cluster 8: Pancreas - Proteolysis | Tissue enriched | Detected in some | 2,112 | Not detected | Not detected | null | Cancer enriched | Detected in single | 77 | Cell type enriched | Detected in some | 14 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,505 | 8 |
ENSG00000138162 | TACC2 | Transforming acidic coiled-coil containing protein 2 | [
"O95359"
] | 10 | 121989163-122254545 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031020",
"HPA031021",
"HPA061394"
] | [
"AZU-1",
"ECTACC"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Supported | Enhanced | null | 12 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 62: Skeletal muscle - Muscle contraction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,506 | 9 |
ENSG00000138166 | DUSP5 | Dual specificity phosphatase 5 | [
"Q16690"
] | 10 | 110497907-110511533 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"HVH3"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [] | [] | [] | [] | null | null | null | 6 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 78: Plasma cells - Antibody production & ER-stress response | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 3 | 0 | 3 | [
"Kidney Chromophobe",
"Rectum Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 7,507 | 4 |
ENSG00000138172 | CALHM2 | Calcium homeostasis modulator family member 2 | [
"Q9HA72"
] | 10 | 103446786-103452402 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014706"
] | [
"FAM26B"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel"
] | [] | [
"Nucleoplasm",
"Mitochondria"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 12: Non-specific - Vasculature | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 7,508 | 6 |
ENSG00000138175 | ARL3 | ADP ribosylation factor like GTPase 3 | [
"P36405"
] | 10 | 102673731-102714397 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036292",
"HPA063596"
] | [
"ARFL3"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Protein transport",
"Transport"
] | [] | [
"Ciliopathy",
"Disease variant",
"Joubert syndrome"
] | [
"Nucleoplasm",
"Centrosome",
"Basal body"
] | [
"Primary cilium"
] | [] | [] | Supported | Approved | null | 42 | null | null | Cluster 4: Neutrophils - Degranulation | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 52: Non-specific - Mitochondria | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 7,509 | 9 |
ENSG00000138182 | KIF20B | Kinesin family member 20B | [
"Q96Q89"
] | 10 | 89701590-89774939 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050214"
] | [
"CT90",
"KRMP1",
"MPHOSPH1",
"MPP1"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [
"Motor protein"
] | [
"Oncogene"
] | [
"Nucleoplasm",
"Cytokinetic bridge",
"Basal body"
] | [
"Midbody",
"Centrosome",
"Cytosol",
"Perinuclear theca"
] | [] | [] | Supported | Supported | null | 8 | Yes | Yes | Cluster 5: Non-specific - Cell proliferation | Cluster 15: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,511 | 6 |
ENSG00000138185 | ENTPD1 | Ectonucleoside triphosphate diphosphohydrolase 1 | [
"P49961"
] | 10 | 95711779-95877266 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002494",
"HPA014067",
"CAB079986"
] | [
"ATPDase",
"CD39",
"NTPDase-1",
"SPG64"
] | [
"CD markers",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [] | [
"Hydrolase"
] | [
"Disease variant",
"Hereditary spastic paraplegia",
"Neurodegeneration"
] | [
"Microtubules"
] | [] | [] | [] | Uncertain | Enhanced | null | 3 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 20: Macrophages & Microglia - Immune response | Cluster 55: Lymphoma - Immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Rectum Adenocarcinoma"
] | 7,512 | 5 |
ENSG00000138190 | EXOC6 | Exocyst complex component 6 | [
"Q8TAG9"
] | 10 | 92826831-93059493 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036285"
] | [
"DKFZp761I2124",
"EXOC6A",
"FLJ1125",
"MGC33397",
"Sec15",
"SEC15L",
"SEC15L1"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Exocytosis",
"Protein transport",
"Transport"
] | [] | [] | [
"Centrosome",
"Basal body",
"Cytosol"
] | [] | [] | [] | Uncertain | Approved | null | 37 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 23: Choroid plexus - Mixed function | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 7,513 | 9 |
ENSG00000138207 | RBP4 | Retinol binding protein 4 | [
"P02753"
] | 10 | 93591687-93601744 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001641",
"CAB004555"
] | [] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins",
"Transporters"
] | [
"Sensory transduction",
"Transport",
"Vision"
] | [] | [
"Cancer-related genes",
"Disease variant",
"Microphthalmia"
] | [] | [] | [
"Secreted to blood"
] | [
"Transport"
] | null | Supported | null | 9 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 18: Liver cancer - Metabolism | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 53: Liver - Plasma proteins | Tissue enriched | Detected in many | 17 | Cancer enriched | Detected in many | 4 | Cancer enriched | Detected in many | 10 | Cell type enriched | Detected in many | 13 | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,515 | 4 |
ENSG00000138231 | DBR1 | Debranching RNA lariats 1 | [
"Q9UK59"
] | 3 | 138160988-138174949 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035365"
] | [] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"mRNA processing"
] | [
"Hydrolase"
] | [
"Disease variant",
"Ichthyosis"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Supported | null | 7 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 55: Non-specific - Transcription | Cluster 63: Non-specific - Protein processing | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,516 | 1 |
ENSG00000138246 | DNAJC13 | DnaJ heat shock protein family (Hsp40) member C13 | [
"O75165"
] | 3 | 132417502-132539032 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036923",
"HPA036924"
] | [
"KIAA0678",
"RME8"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [
"Protein transport",
"Transport"
] | [
"Chaperone"
] | [
"Disease variant",
"Neurodegeneration",
"Parkinson disease",
"Parkinsonism"
] | [
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 35 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,517 | 2 |
ENSG00000138271 | GPR87 | G protein-coupled receptor 87 | [
"Q9BY21"
] | 3 | 151294086-151316820 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA066313"
] | [
"GPR95"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [
"Lipid droplets",
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Approved | null | null | null | No | No | null | Cluster 23: Choroid plexus - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 7,518 | 7 |
ENSG00000138279 | ANXA7 | Annexin A7 | [
"P20073"
] | 10 | 73375101-73414076 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004312"
] | [
"ANX7"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Approved | null | 5 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 14: Neurons - Synaptic function | Cluster 52: Non-specific - Mitochondria | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,519 | 6 |
ENSG00000138286 | FAM149B1 | Family with sequence similarity 149 member B1 | [
"Q96BN6"
] | 10 | 73168119-73244504 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039189",
"HPA039859"
] | [
"KIAA0974"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [
"Ciliopathy",
"Disease variant",
"Joubert syndrome"
] | [
"Microtubules",
"Primary cilium"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 41: Basophils - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in single | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 7,520 | 4 |
ENSG00000138303 | ASCC1 | Activating signal cointegrator 1 complex subunit 1 | [
"Q8N9N2"
] | 10 | 72096032-72217134 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038038",
"HPA057567"
] | [
"ASC1p50",
"CGI-18",
"Em:AC022392.3",
"p50"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Transcription",
"Transcription regulation"
] | [] | [
"Neurodegeneration"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 16 | null | null | Cluster 32: Basophils - Transcription | Cluster 55: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 4 | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,521 | 8 |
ENSG00000138308 | PLA2G12B | Phospholipase A2 group XIIB | [
"Q9BX93"
] | 10 | 72934762-72954806 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA057745",
"HPA059562"
] | [
"PLA2G13"
] | [
"Plasma proteins",
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | null | Approved | null | null | null | null | null | null | Cluster 1: Neuronal - Visual perception | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 26: Kidney & Intestine - Metabolism | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in some | 7 | Cancer enriched | Detected in many | 6 | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,522 | 6 |
ENSG00000138311 | ZNF365 | Zinc finger protein 365 | [
"Q70YC5"
] | 10 | 62374192-62480288 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052446"
] | [
"KIAA0844",
"Su48",
"UAN"
] | [
"Predicted intracellular proteins"
] | [
"Neurogenesis"
] | [] | [] | [
"Centriolar satellite",
"Centrosome"
] | [
"Vesicles"
] | [] | [] | Approved | Supported | null | 3 | null | null | Cluster 15: NK-cells - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 73: Brain - Neuronal signaling | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in many | 9 | 0 | 0 | 0 | [] | [] | [] | 7,523 | 7 |
ENSG00000138315 | OIT3 | Oncoprotein induced transcript 3 | [
"Q8WWZ8"
] | 10 | 72893584-72933036 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"FLJ39116",
"LZP"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | null | null | null | 9 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 1: Neuronal - Visual perception | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 12 | Cancer enriched | Detected in single | 4 | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,524 | 9 |
ENSG00000138316 | ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif 14 | [
"Q8WXS8"
] | 10 | 70672506-70762441 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA079400"
] | [] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Collagen degradation"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Cancer-related genes"
] | [
"Golgi apparatus",
"Vesicles"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Enzyme"
] | Approved | null | null | null | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 47: Leukemia - Hemostasis | Cluster 108: Fibroblasts - ECM organization | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Lung Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Lung Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 7,525 | 3 |
ENSG00000138326 | RPS24 | Ribosomal protein S24 | [
"P62847"
] | 10 | 78033760-78056813 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003364",
"HPA073508"
] | [
"eS24",
"S24"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [
"Diamond-Blackfan anemia"
] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 142 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 7,526 | 1 |
ENSG00000138336 | TET1 | Tet methylcytosine dioxygenase 1 | [
"Q8NFU7"
] | 10 | 68560337-68694487 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019032"
] | [
"bA119F7.1",
"CXXC6",
"KIAA1676",
"LCX"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Chromatin regulator",
"Developmental protein",
"Dioxygenase",
"DNA-binding",
"Oxidoreductase",
"Repressor"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Nuclear membrane"
] | [] | [] | Supported | null | null | 5 | null | null | null | Cluster 25: Non-specific - Transcription | Cluster 34: Testis cancer - Unknown function | Cluster 89: Adipocytes - Lipid metabolism | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in some | null | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in single | 16 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Lung Squamous Cell Carcinoma"
] | 7,527 | 3 |
ENSG00000138346 | DNA2 | DNA replication helicase/nuclease 2 | [
"P51530"
] | 10 | 68414064-68472121 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037487",
"HPA057526"
] | [
"DNA2L",
"KIAA0083"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"DNA replication"
] | [
"DNA-binding",
"Endonuclease",
"Helicase",
"Hydrolase",
"Multifunctional enzyme",
"Nuclease"
] | [
"Disease variant",
"Dwarfism",
"Ectodermal dysplasia",
"Hypotrichosis",
"Intellectual disability",
"Primary mitochondrial disease",
"Progressive external ophthalmoplegia"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Approved | null | 23 | No | Yes | null | Cluster 34: Non-specific - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 27: Non-specific - Cell proliferation | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 5 | 5 | 0 | 5 | [
"Glioblastoma Multiforme"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,528 | 5 |
ENSG00000138347 | MYPN | Myopalladin | [
"Q86TC9"
] | 10 | 68087897-68212017 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036299",
"HPA061494"
] | [
"MYOP"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [
"Cardiomyopathy",
"Disease variant",
"Nemaline myopathy"
] | [
"Nucleoplasm"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 2 | No | No | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 29: Forebrain - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in many | 5 | Cancer enhanced | Detected in single | null | Cell type enriched | Detected in many | 4 | Group enriched | Detected in some | 27 | 0 | 0 | 0 | [] | [] | [] | 7,529 | 7 |
ENSG00000138356 | AOX1 | Aldehyde oxidase 1 | [
"Q06278"
] | 2 | 200586014-200677064 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040199",
"HPA040215"
] | [
"AO",
"AOH1"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Oxidoreductase"
] | [] | [
"Cytosol"
] | [
"Nuclear bodies",
"Microtubules",
"Cytokinetic bridge"
] | [] | [] | Supported | Enhanced | null | null | Yes | null | null | Cluster 11: White matter - Signal transduction | Cluster 44: Connective tissue cells - ECM organization | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 76: Non-specific - Metabolism | Group enriched | Detected in many | 6 | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in many | 7 | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 7,530 | 9 |
ENSG00000138363 | ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | [
"P31939"
] | 2 | 215311956-215349773 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013462",
"HPA021012"
] | [
"AICARFT",
"IMPCHASE",
"PURH"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Purine biosynthesis"
] | [
"Hydrolase",
"Multifunctional enzyme",
"Transferase"
] | [
"Cancer-related genes",
"Disease variant",
"Epilepsy",
"FDA approved drug targets",
"Intellectual disability"
] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Supported | null | 8 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 7,531 | 4 |
ENSG00000138376 | BARD1 | BRCA1 associated RING domain 1 | [
"Q99728"
] | 2 | 214725646-214809683 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB034106",
"HPA035354",
"HPA044864"
] | [] | [
"Cancer-related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Nuclear speckles"
] | [
"Cytoplasmic bodies"
] | [] | [] | Supported | Enhanced | null | 102 | No | Yes | Cluster 5: Non-specific - Cell proliferation | Cluster 19: Astrocytes - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 27: Non-specific - Cell proliferation | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 7,533 | 3 |
ENSG00000138378 | STAT4 | Signal transducer and activator of transcription 4 | [
"Q14765"
] | 2 | 191029576-191151596 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001860",
"CAB013108"
] | [] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant",
"Systemic lupus erythematosus"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Flagellar centriole"
] | [] | [] | Supported | Enhanced | null | 8 | null | null | Cluster 1: T-cells - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 35: Non-specific - Mixed function | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Breast Invasive Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,534 | 3 |
ENSG00000138379 | MSTN | Myostatin | [
"O14793"
] | 2 | 190055700-190062729 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB009963"
] | [
"GDF8"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted secreted proteins"
] | [] | [
"Cytokine",
"Growth factor",
"Heparin-binding"
] | [] | [] | [] | [
"Secreted in other tissues"
] | [
"Cytokine"
] | null | Approved | null | 18 | null | null | null | Cluster 31: Non-specific - Transcription | Cluster 33: Sarcoma - Muscle contraction | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 30: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in some | 4 | Cancer enriched | Detected in some | 7 | Cancer enriched | Detected in some | 6 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 7,535 | 8 |
ENSG00000138380 | CARF | Calcium responsive transcription factor | [
"Q8N187"
] | 2 | 202912214-202988263 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA034557",
"HPA043191"
] | [
"ALS2CR8",
"FLJ21579",
"NYD-SP24"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Vesicles"
] | [
"Nucleoli fibrillar center",
"Cytosol"
] | [] | [] | Approved | Approved | null | 5 | null | null | Cluster 16: Non-specific - Cell proliferation | Cluster 11: White matter - Signal transduction | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 7,536 | 6 |
ENSG00000138381 | ASNSD1 | Asparagine synthetase domain containing 1 | [
"Q9NWL6"
] | 2 | 189661385-189670831 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA036132",
"HPA036133",
"HPA075042"
] | [
"FLJ20752",
"NBLA00058",
"NS3TP1"
] | [
"Predicted intracellular proteins"
] | [
"Amino-acid biosynthesis",
"Asparagine biosynthesis"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | null | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 16: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 4 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,537 | 9 |
ENSG00000138382 | METTL5 | Methyltransferase 5, N6-adenosine | [
"Q9NRN9"
] | 2 | 169810081-169824931 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038223"
] | [
"HSPC133"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Methyltransferase",
"Transferase"
] | [
"Intellectual disability"
] | [
"Nucleoli",
"Nucleoli fibrillar center"
] | [
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 2 | null | null | Cluster 11: T-cells - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 97: Non-specific - Cellular respiration | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,538 | 5 |
ENSG00000138385 | SSB | Small RNA binding exonuclease protection factor La | [
"P05455"
] | 2 | 169791933-169812064 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004643",
"HPA017287"
] | [
"La",
"La/SSB",
"LARP3"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [
"RNA-binding"
] | [
"Systemic lupus erythematosus"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Supported | null | 229 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 23: Choroid plexus - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 17: Non-specific - RNA processing | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 7,539 | 2 |
ENSG00000138386 | NAB1 | NGFI-A binding protein 1 | [
"Q13506"
] | 2 | 190646746-190692766 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002738"
] | [] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [] | [
"Nucleoplasm",
"Plasma membrane"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Uncertain | null | 3 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 16: Non-specific - Transcription | Cluster 5: Rhabdoid - Unknown function | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,540 | 3 |
ENSG00000138395 | CDK15 | Cyclin dependent kinase 15 | [
"Q96Q40"
] | 2 | 201790461-201895550 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA015786"
] | [
"ALS2CR7",
"PFTAIRE2",
"PFTK2"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm",
"Golgi apparatus"
] | [] | [] | [] | Approved | Uncertain | null | 7 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 35: Non-specific - DNA binding | Cluster 49: HMC-1 - Innate immune response | Cluster 58: Mast cells - Allergic inflammatory responses | Cluster 22: Epididymis - Mixed function | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in single | null | Cell type enriched | Detected in some | 5 | Group enriched | Detected in some | 28 | 0 | 0 | 0 | [] | [] | [] | 7,541 | 8 |
ENSG00000138400 | MDH1B | Malate dehydrogenase 1B | [
"Q5I0G3"
] | 2 | 206737763-206765328 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA073761"
] | [
"FLJ25341",
"RP11-95H11"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Tricarboxylic acid cycle"
] | [
"Oxidoreductase"
] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 3: Choroid plexus - Cilium | Cluster 10: Ciliated cells - Ion channel activity | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,544 | 1 |
ENSG00000138411 | HECW2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 | [
"Q9P2P5"
] | 2 | 196189099-196593684 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034609"
] | [
"KIAA1301",
"NEDL2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 14 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,545 | 8 |
ENSG00000138413 | IDH1 | Isocitrate dehydrogenase (NADP(+)) 1 | [
"O75874"
] | 2 | 208236229-208266074 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB033218",
"HPA035248",
"HPA057936",
"CAB062556"
] | [] | [
"Cancer-related genes",
"Citric acid cycle related proteins",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Glyoxylate bypass",
"Tricarboxylic acid cycle"
] | [
"Oxidoreductase"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Nuclear bodies",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 19 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 21: Non-specific - Metabolism | Cluster 7: Liver cancer - Metabolism | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Chromophobe"
] | 7,546 | 8 |
ENSG00000138430 | OLA1 | Obg like ATPase 1 | [
"Q9NTK5"
] | 2 | 174072447-174248599 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035790",
"HPA041443"
] | [
"GTPBP9",
"PTD004"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 12 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 14: Neurons - Synaptic function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 7,547 | 4 |
ENSG00000138433 | CIR1 | Corepressor interacting with RBPJ, CIR1 | [
"Q86X95"
] | 2 | 174348022-174395712 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015784",
"HPA061442"
] | [
"CIR"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing",
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Approved | null | 14 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 31: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 7,548 | 8 |
ENSG00000138434 | ITPRID2 | ITPR interacting domain containing 2 | [
"P28290"
] | 2 | 181891730-181930738 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034665",
"HPA039989"
] | [
"CS-1",
"KIAA1927",
"KRAP",
"SPAG13",
"SSFA2"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Uncertain | null | 28 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 19: Astrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 8: Pancreas - Proteolysis | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,549 | 2 |
ENSG00000138435 | CHRNA1 | Cholinergic receptor nicotinic alpha 1 subunit | [
"P02708"
] | 2 | 174747592-174787935 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA071554"
] | [
"CHRNA"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"Congenital myasthenic syndrome",
"Disease variant"
] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 1 | null | null | null | Cluster 29: Forebrain - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enriched | Detected in some | 8 | Cancer enriched | Detected in some | 16 | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,550 | 8 |
ENSG00000138439 | FAM117B | Family with sequence similarity 117 member B | [
"Q6P1L5"
] | 2 | 202634969-202769757 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003229",
"HPA028746"
] | [
"ALS2CR13",
"FLJ38771"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Centrosome"
] | [] | [] | Approved | Uncertain | null | 43 | Yes | No | Cluster 24: Non-specific - Transcription | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 7,551 | 4 |
ENSG00000138442 | WDR12 | WD repeat domain 12 | [
"Q9GZL7"
] | 2 | 202874261-203014798 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036389"
] | [
"FLJ10881",
"YTM1"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis",
"rRNA processing"
] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Nucleoli"
] | [] | [] | Approved | Uncertain | null | 35 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,552 | 9 |
ENSG00000138443 | ABI2 | Abl interactor 2 | [
"Q9NYB9"
] | 2 | 203328280-203447728 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA070567"
] | [
"ABI-2",
"ABI2B",
"AblBP3",
"AIP-1",
"argBPIA",
"SSH3BP2"
] | [
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Neurogenesis"
] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 167 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 33: Neurons - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,553 | 1 |
ENSG00000138448 | ITGAV | Integrin subunit alpha V | [
"P06756"
] | 2 | 186590010-186680901 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002499",
"HPA004856"
] | [
"CD51",
"MSK8",
"VNRA",
"VTNR"
] | [
"Cancer-related genes",
"CD markers",
"FDA approved drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Cell adhesion",
"Host-virus interaction"
] | [
"Host cell receptor for virus entry",
"Integrin",
"Receptor"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Focal adhesion sites",
"Cytosol"
] | [] | [] | [] | Approved | Supported | null | 26 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 27: Non-specific - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 99: Retinal pigment epithelial cells - Retinol metabolism | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 7,554 | 1 |
ENSG00000138449 | SLC40A1 | Solute carrier family 40 member 1 | [
"Q9NP59"
] | 2 | 189560590-189583758 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065634"
] | [
"FPN1",
"HFE4",
"IREG1",
"MTP1",
"SLC11A3"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Iron transport",
"Transport"
] | [] | [
"Disease variant"
] | [
"Plasma membrane",
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Immune cell enhanced | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,555 | 1 |
ENSG00000138459 | SLC35A5 | Solute carrier family 35 member A5 | [
"Q9BS91"
] | 3 | 112561709-112585579 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035519",
"HPA057964"
] | [
"FLJ20730"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Sugar transport",
"Transport"
] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Uncertain | null | 9 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 30: White matter - Myelination | Cluster 63: Non-specific - Protein processing | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 4 | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 7,556 | 1 |
ENSG00000138463 | SLC49A4 | Solute carrier family 49 member 4 | [
"Q96SL1"
] | 3 | 122795069-122881139 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA072579"
] | [
"DIRC2",
"FLJ14784",
"RCC4"
] | [
"Disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | null | null | null | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,557 | 8 |
ENSG00000138468 | SENP7 | SUMO specific peptidase 7 | [
"Q9BQF6"
] | 3 | 101324205-101513241 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027259",
"HPA071998"
] | [] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Immunity",
"Innate immunity",
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Centrosome",
"Cytosol"
] | [] | [] | Supported | Approved | null | 7 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 25: Non-specific - Transcription | Cluster 56: Non-specific - Sensory perception | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 7,558 | 1 |
ENSG00000138472 | GUCA1C | Guanylate cyclase activator 1C | [
"O95843"
] | 3 | 108907792-108953879 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041597"
] | [
"GCAP3"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Focal adhesion sites"
] | [] | [] | [] | Approved | Uncertain | null | 2 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in some | 7 | Cancer enriched | Detected in single | 14 | Not detected | Not detected | null | Cell type enriched | Detected in some | 12 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,559 | 3 |
ENSG00000138483 | CCDC54 | Coiled-coil domain containing 54 | [
"Q8NEL0"
] | 3 | 107377439-107378635 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"FLJ25362",
"NYD-SP17",
"SP17"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 33: Sarcoma - Muscle contraction | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 6: Testis - Spermatogenesis | Tissue enriched | Detected in single | 127 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,560 | 7 |
ENSG00000138495 | COX17 | Cytochrome c oxidase copper chaperone COX17 | [
"Q14061"
] | 3 | 119654513-119677454 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042226",
"HPA048158"
] | [] | [
"Cancer-related genes",
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [
"Chaperone"
] | [
"Cancer-related genes"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Supported | null | 8 | null | null | Cluster 32: Basophils - Transcription | Cluster 44: Non-specific - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 7,561 | 7 |
ENSG00000138496 | PARP9 | Poly(ADP-ribose) polymerase family member 9 | [
"Q8IXQ6"
] | 3 | 122527924-122564577 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA066708"
] | [
"ARTD9",
"BAL",
"BAL1"
] | [
"Disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"DNA damage",
"DNA repair",
"Immunity",
"Innate immunity"
] | [
"Glycosyltransferase",
"Nucleotidyltransferase",
"Transferase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Mitochondria"
] | [] | [] | Supported | null | null | 5 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 43: Hindbrain - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 7,562 | 8 |
ENSG00000138587 | MNS1 | Meiosis specific nuclear structural 1 | [
"Q8NEH6"
] | 15 | 56421544-56465137 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039975",
"HPA040382"
] | [
"FLJ11222",
"SPATA40"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Meiosis"
] | [] | [
"Disease variant",
"Heterotaxy"
] | [
"Nucleoplasm",
"Nuclear speckles",
"Primary cilium",
"End piece"
] | [
"Basal body",
"Cytosol",
"Perinuclear theca",
"Flagellar centriole"
] | [] | [] | Approved | Uncertain | null | 26 | null | null | null | Cluster 50: Non-specific - Nucleic acid binding | Cluster 11: Neuronal - Sensory perception | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 7,563 | 7 |
ENSG00000138592 | USP8 | Ubiquitin specific peptidase 8 | [
"P40818"
] | 15 | 50424380-50514421 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA050215"
] | [
"HumORF8",
"KIAA0055",
"SPG59",
"UBPY"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Cancer-related genes",
"Cushing syndrome",
"Disease variant"
] | [
"Vesicles"
] | [
"Nucleoplasm",
"Golgi apparatus",
"Cytosol"
] | [] | [] | Approved | Approved | null | 69 | null | null | Cluster 32: Basophils - Transcription | Cluster 44: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 7,564 | 1 |
ENSG00000138593 | SECISBP2L | SECIS binding protein 2 like | [
"Q93073"
] | 15 | 48988476-49046447 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039875"
] | [
"KIAA0256"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 7 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 30: White matter - Myelination | Cluster 60: Prostate cancer - Unknown function | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 4 | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,565 | 3 |
ENSG00000138594 | TMOD3 | Tropomodulin 3 | [
"Q9NYL9"
] | 15 | 51829628-51947295 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001849"
] | [
"UTMOD"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [
"Cytosol"
] | [
"Actin filaments"
] | [] | [] | Approved | Approved | null | 24 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 12: Non-specific - Vasculature | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,566 | 6 |
ENSG00000138600 | SPPL2A | Signal peptide peptidase like 2A | [
"Q8TCT8"
] | 15 | 50702266-50765948 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036062",
"HPA067304"
] | [
"IMP3",
"PSL2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Hydrolase",
"Protease"
] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | Enhanced | null | 2 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 8: Immune cells - Immune response | Cluster 58: Non-specific - Nuclear processes | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 7,567 | 5 |
ENSG00000138604 | GLCE | Glucuronic acid epimerase | [
"O94923"
] | 15 | 69160584-69272217 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040481",
"HPA048216"
] | [
"HSEPI",
"KIAA0836"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Isomerase"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Uncertain | null | 2 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 35: Non-specific - DNA binding | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 7,568 | 4 |
ENSG00000138606 | SHF | Src homology 2 domain containing F | [
"Q7M4L6"
] | 15 | 45167214-45201175 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA057381"
] | [] | [
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | null | null | null | null | Cluster 33: Non-specific - ATP binding | Cluster 35: Non-specific - DNA binding | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 64: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 7,569 | 6 |
ENSG00000138614 | INTS14 | Integrator complex subunit 14 | [
"Q96SY0"
] | 15 | 65578753-65611289 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040255",
"HPA040651"
] | [
"C15orf44",
"DKFZP564O1664",
"VWA9"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Nuclear bodies",
"Mitochondria"
] | [
"Nuclear membrane"
] | [] | [] | Approved | Approved | null | 40 | No | No | Cluster 5: Non-specific - Cell proliferation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 58: Non-specific - Nuclear processes | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,571 | 4 |
ENSG00000138615 | CILP | Cartilage intermediate layer protein | [
"O75339"
] | 15 | 65194760-65211473 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA003195"
] | [
"HsT18872"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | null | Uncertain | null | null | null | null | null | null | Cluster 15: Kidney cancer - Membrane components | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Group enriched | Detected in some | 12 | Cancer enriched | Detected in many | 4 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Thyroid Carcinoma"
] | [
"Thyroid Carcinoma"
] | 7,572 | 6 |
ENSG00000138617 | PARP16 | Poly(ADP-ribose) polymerase family member 16 | [
"Q8N5Y8"
] | 15 | 65234460-65300618 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA017081"
] | [
"ARTD15",
"C15orf30",
"FLJ20509",
"FLJ25281",
"pART15"
] | [
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Unfolded protein response"
] | [
"Glycosyltransferase",
"Nucleotidyltransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Approved | null | 3 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 15: Non-specific - Transcription | Cluster 58: Non-specific - Nuclear processes | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 7,573 | 3 |
ENSG00000138621 | PPCDC | Phosphopantothenoylcysteine decarboxylase | [
"Q96CD2"
] | 15 | 75023586-75117462 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045667"
] | [
"FLJ14585",
"MDS018"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Coenzyme A biosynthesis"
] | [
"Decarboxylase",
"Lyase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 10 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 58: Non-specific - Nuclear processes | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,574 | 2 |
ENSG00000138622 | HCN4 | Hyperpolarization activated cyclic nucleotide gated potassium channel 4 | [
"Q9Y3Q4"
] | 15 | 73319859-73368958 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA073174"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Potassium transport",
"Sodium transport",
"Transport"
] | [
"Ion channel",
"Ligand-gated ion channel",
"Potassium channel",
"Sodium channel",
"Voltage-gated channel"
] | [
"Brugada syndrome",
"Disease variant",
"Epilepsy"
] | [] | [] | [] | [] | null | Approved | null | 5 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 109: Neurons - Neuronal signaling | Cluster 35: Non-specific - Mixed function | Group enriched | Detected in some | 6 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in single | 5 | Group enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,575 | 8 |
ENSG00000138623 | SEMA7A | Semaphorin 7A (John Milton Hagen blood group) | [
"O75326"
] | 15 | 74409289-74433958 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008210",
"HPA042273"
] | [
"CD108",
"H-Sema-L",
"SEMAL"
] | [
"Blood group antigen proteins",
"CD markers",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Differentiation",
"Inflammatory response",
"Neurogenesis"
] | [
"Developmental protein"
] | [
"Disease variant",
"Intrahepatic cholestasis"
] | [
"Vesicles"
] | [] | [] | [] | Uncertain | Uncertain | null | 3 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 30: White matter - Myelination | Cluster 55: Lymphoma - Immune response | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in some | 4 | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 7,576 | 4 |
ENSG00000138629 | UBL7 | Ubiquitin like 7 | [
"Q96S82"
] | 15 | 74445977-74461182 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040423",
"HPA041897"
] | [
"BMSC-UbP",
"MGC14421"
] | [
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"Immunity",
"Innate immunity",
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 15 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 14: Neurons - Synaptic function | Cluster 58: Non-specific - Nuclear processes | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 7,577 | 9 |
ENSG00000138639 | ARHGAP24 | Rho GTPase activating protein 24 | [
"Q8N264"
] | 4 | 85475150-86002668 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014288"
] | [
"DKFZP564B1162",
"FilGAP",
"FLJ33877"
] | [
"Predicted intracellular proteins"
] | [
"Angiogenesis",
"Differentiation"
] | [
"Developmental protein",
"GTPase activation"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 13 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 49: Hindbrain - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 7,578 | 7 |
ENSG00000138640 | FAM13A | Family with sequence similarity 13 member A | [
"O94988"
] | 4 | 88725955-89111398 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038108",
"HPA038109"
] | [
"ARHGAP48",
"FAM13A1",
"KIAA0914"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Cytosol"
] | [
"Nucleoli",
"Cell Junctions"
] | [] | [] | Approved | Uncertain | null | 10 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 5: Non-specific - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 89: Adipocytes - Lipid metabolism | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,579 | 4 |
ENSG00000138642 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | [
"Q8IVU3"
] | 4 | 88378739-88443097 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035846"
] | [
"FLJ20637"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 1 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 53: Neurons - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 104: Brain endothelial cells - Blood brain barrier | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 7,581 | 3 |
ENSG00000138646 | HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | [
"Q9UII4"
] | 4 | 88457119-88506163 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043929"
] | [
"CEB1"
] | [
"Predicted membrane proteins"
] | [
"Antiviral defense",
"Host-virus interaction",
"Immunity",
"Innate immunity",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [] | [] | [] | [] | null | Supported | null | 45 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 46: Brainstem - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 106: Spermatogonia - Spermatogonial differentiation | Cluster 57: Testis - Spermatogenesis | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enriched | Detected in all | 5 | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 7,582 | 2 |
ENSG00000138650 | PCDH10 | Protocadherin 10 | [
"Q9P2E7"
] | 4 | 133149294-133208606 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011220",
"HPA073462"
] | [
"KIAA1400",
"OL-PCDH"
] | [
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [
"Receptor"
] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | Approved | Approved | null | 7 | No | null | null | Cluster 33: Neurons - Mixed function | Cluster 3: Rhabdoid - Membrane components | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 73: Brain - Neuronal signaling | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,583 | 7 |
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