ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000139352
ASCL1
Achaete-scute family bHLH transcription factor 1
[ "P50553" ]
12
102957674-102960513
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029217", "HPA076307" ]
[ "ASH1", "bHLHa46", "HASH1" ]
[ "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Differentiation", "Neurogenesis", "Transcription", "Transcription regulation" ]
[ "Activator", "Developmental protein", "DNA-binding" ]
[ "Disease variant" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
12
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 10: Ciliated cells - Ion channel activity
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 36: Brain & Liver - Signaling
Tissue enhanced
Detected in some
null
Group enriched
Detected in some
4
Group enriched
Detected in many
4
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,697
3
ENSG00000139354
GAS2L3
Growth arrest specific 2 like 3
[ "Q86XJ1" ]
12
100573683-100628288
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA048593" ]
[]
[ "Predicted intracellular proteins" ]
[]
[ "Actin-binding" ]
[]
[]
[]
[]
[]
null
Approved
null
12
null
Yes
Cluster 26: Monocytes - Plasma membrane proteins
Cluster 48: Non-specific - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
7,698
1
ENSG00000139364
TMEM132B
Transmembrane protein 132B
[ "Q14DG7" ]
12
125186386-125662377
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA035661", "HPA035662" ]
[ "KIAA1786", "KIAA1906" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 12: Bone cancer - Neuronal signaling
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 73: Brain - Neuronal signaling
Tissue enriched
Detected in some
6
Cancer enriched
Detected in some
6
Cancer enriched
Detected in single
9
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,699
2
ENSG00000139370
SLC15A4
Solute carrier family 15 member 4
[ "Q8N697" ]
12
128793194-128823958
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016713" ]
[ "PHT1", "PTR4" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Immunity", "Innate immunity", "Peptide transport", "Protein transport", "Symport", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
20
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 15: Kidney cancer - Membrane components
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,700
8
ENSG00000139372
TDG
Thymine DNA glycosylase
[ "Q13569" ]
12
103965822-103988874
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA052263" ]
[]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "Transcription", "Transcription regulation" ]
[ "Activator", "Chromatin regulator", "Hydrolase" ]
[]
[ "Nucleoplasm" ]
[ "Plasma membrane" ]
[]
[]
Supported
Supported
null
31
null
null
Cluster 29: Non-specific - Unknown function
Cluster 53: Neurons - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
7,701
5
ENSG00000139405
RITA1
RBPJ interacting and tubulin associated 1
[ "Q96K30" ]
12
113185526-113192368
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039094", "HPA039095", "HPA061531" ]
[ "C12orf52", "FLJ14827", "RITA" ]
[ "Predicted intracellular proteins" ]
[ "Neurogenesis", "Notch signaling pathway" ]
[]
[]
[ "Nucleoplasm" ]
[ "Golgi apparatus", "Primary cilium", "Primary cilium tip", "Cytosol" ]
[]
[]
Supported
Supported
null
6
No
No
Cluster 41: Basophils - Unknown function
Cluster 38: Sub-cortical - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
7,702
1
ENSG00000139410
SDSL
Serine dehydratase like
[ "Q96GA7" ]
12
113422380-113438276
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA005740" ]
[ "cSDH", "SDS-RS1" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Lipid metabolism" ]
[ "Isomerase", "Lyase" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
1
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 27: Breast cancer - Unknown function
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 70: Non-specific - Protein processing
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
6
1
0
1
[]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe" ]
7,703
5
ENSG00000139428
MMAB
Metabolism of cobalamin associated B
[ "Q96EY8" ]
12
109553715-109573580
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039017" ]
[ "cblB", "CFAP23" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Transferase" ]
[ "Disease variant" ]
[ "Mitochondria" ]
[]
[]
[]
Approved
Supported
null
19
null
null
Cluster 30: Non-specific - DNA binding
Cluster 30: White matter - Myelination
Cluster 35: RS4;11 - Unknown function
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 70: Non-specific - Protein processing
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
7,704
2
ENSG00000139433
GLTP
Glycolipid transfer protein
[ "Q9NZD2" ]
12
109850945-109880541
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA056461", "HPA065503" ]
[]
[ "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Lipid transport", "Transport" ]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
3
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 30: White matter - Myelination
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Thyroid Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
7,705
9
ENSG00000139436
GIT2
GIT ArfGAP 2
[ "Q14161" ]
12
109929804-109996389
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004681" ]
[ "KIAA0148", "PKL" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "GTPase activation" ]
[]
[ "Microtubules" ]
[]
[]
[]
Approved
Approved
null
36
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 37: Neurons - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
7,706
6
ENSG00000139437
TCHP
Trichoplein keratin filament binding
[ "Q9BT92" ]
12
109900264-109983841
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038638", "HPA061543" ]
[ "MGC10854", "TpMs" ]
[ "Predicted intracellular proteins" ]
[ "Apoptosis", "Cilium biogenesis/degradation" ]
[]
[ "Tumor suppressor" ]
[ "Plasma membrane", "Cytosol" ]
[ "Primary cilium", "Centrosome", "Basal body", "Mid piece", "Principal piece" ]
[]
[]
Approved
Supported
null
63
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 6: Non-specific - Immune response
Cluster 38: Non-specific - Transcription
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 2: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
7,707
5
ENSG00000139438
FAM222A
Family with sequence similarity 222 member A
[ "Q5U5X8" ]
12
109713825-109770495
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA040181", "HPA075616" ]
[ "C12orf34", "FLJ14721" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Golgi apparatus" ]
[ "Cell Junctions", "Midbody ring" ]
[]
[]
Approved
Uncertain
null
1
Yes
null
null
Cluster 6: Non-specific - Immune response
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 20: Non-specific - Transcription regulation
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in many
7
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
[]
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
7,708
6
ENSG00000139445
FOXN4
Forkhead box N4
[ "Q96NZ1" ]
12
109277978-109309284
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA050018" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Neurogenesis", "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm", "Mitochondria" ]
[ "Cytosol" ]
[]
[]
Approved
Uncertain
null
3
null
null
null
Cluster 42: Choroid plexus - Mitochondria
Cluster 10: Ciliated cells - Ion channel activity
Cluster 89: Adipocytes - Lipid metabolism
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in some
11
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,709
6
ENSG00000139496
NUP58
Nucleoporin 58
[ "Q9BVL2" ]
13
25301524-25365390
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039360" ]
[ "KIAA0410", "NUP45", "NUPL1" ]
[ "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins", "Transporters" ]
[ "mRNA transport", "Protein transport", "Translocation", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
91
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 31: Non-specific - Transcription
Cluster 19: Non-specific - Unknown function
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
7,710
8
ENSG00000139505
MTMR6
Myotubularin related protein 6
[ "Q9Y217" ]
13
25246222-25287510
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Endocytosis", "Lipid metabolism" ]
[ "Hydrolase" ]
[]
[]
[]
[]
[]
null
null
null
8
null
null
Cluster 28: Neutrophils - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 19: Non-specific - Unknown function
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
7,711
8
ENSG00000139508
SLC46A3
Solute carrier family 46 member 3
[ "Q7Z3Q1" ]
13
28700064-28718970
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039930" ]
[ "DKFZp686A1775", "FLJ42613" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Symport", "Transport" ]
[]
[]
[ "Plasma membrane", "Cytosol" ]
[ "Actin filaments" ]
[]
[]
Approved
Approved
null
1
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 42: Choroid plexus - Mitochondria
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
7,712
1
ENSG00000139514
SLC7A1
Solute carrier family 7 member 1
[ "P30825" ]
13
29509414-29595688
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039721", "HPA077838" ]
[ "ATRC1", "CAT-1", "ERR", "HCAT1", "REC1L" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Amino-acid transport", "Transport" ]
[ "Receptor" ]
[]
[]
[]
[]
[]
null
Approved
null
112
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 49: Hindbrain - Mixed function
Cluster 13: Non-specific - Mixed function
Cluster 104: Brain endothelial cells - Blood brain barrier
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
2
0
2
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
7,713
5
ENSG00000139515
PDX1
Pancreatic and duodenal homeobox 1
[ "P52945" ]
13
27920000-27926313
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB025873", "HPA059146" ]
[ "GSF", "IDX-1", "IPF1", "IUF-1", "MODY4", "PDX-1", "STF-1" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "Developmental protein", "DNA-binding" ]
[ "Diabetes mellitus", "Disease variant" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Enhanced
null
6
null
null
null
null
Cluster 59: Leukemia - T-cell receptor
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 60: Stomach - Digestion
Group enriched
Detected in some
5
Cancer enhanced
Detected in some
null
Group enriched
Detected in many
5
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,714
4
ENSG00000139517
LNX2
Ligand of numb-protein X 2
[ "Q8N448" ]
13
27545913-27620529
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA040698" ]
[ "MGC46315", "PDZRN1" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
Approved
Approved
null
96
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 5: Non-specific - Mixed function
Cluster 19: Non-specific - Unknown function
Cluster 81: Alveolar cells - Lung function
Cluster 60: Stomach - Digestion
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in some
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
7,715
3
ENSG00000139531
SUOX
Sulfite oxidase
[ "P51687" ]
12
55997180-56006641
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA038208", "HPA038209" ]
[]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Oxidoreductase" ]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[]
[]
[]
[]
null
Approved
null
69
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
4
0
4
[ "Colon Adenocarcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Colon Adenocarcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
7,716
5
ENSG00000139537
CCDC65
Coiled-coil domain containing 65
[ "Q8IXS2" ]
12
48904110-48931840
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038520", "HPA057573" ]
[ "CFAP250", "CILD27", "DRC2", "FAP250", "FLJ35732", "NYD-SP28" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Ciliopathy", "Kartagener syndrome", "Primary ciliary dyskinesia" ]
[ "Vesicles", "Primary cilium transition zone", "Centriolar satellite" ]
[ "Mid piece", "Principal piece", "Annulus" ]
[]
[]
Approved
Uncertain
null
2
null
null
Cluster 11: T-cells - Unknown function
Cluster 17: Choroid plexus - Cilium
Cluster 56: Non-specific - Sensory perception
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 56: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
8
2
0
2
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma" ]
7,717
8
ENSG00000139540
SLC39A5
Solute carrier family 39 member 5
[ "Q6ZMH5" ]
12
56230049-56237846
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018423" ]
[]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport", "Zinc transport" ]
[]
[ "Disease variant" ]
[ "Vesicles" ]
[ "Nucleoplasm" ]
[]
[]
Approved
null
null
13
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 60: Stomach - Digestion
Group enriched
Detected in some
32
Group enriched
Detected in some
7
Cancer enhanced
Detected in many
null
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,718
5
ENSG00000139546
TARBP2
TARBP2 subunit of RISC loading complex
[ "Q15633" ]
12
53500921-53506431
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051181", "HPA061454", "CAB069406" ]
[ "Trbp" ]
[ "Predicted intracellular proteins" ]
[ "RNA-mediated gene silencing", "Translation regulation" ]
[ "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nuclear bodies" ]
[]
[]
Supported
Approved
null
42
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 25: Non-specific - Transcription
Cluster 38: Non-specific - Transcription
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
4
0
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
7,719
5
ENSG00000139547
RDH16
Retinol dehydrogenase 16
[ "O75452" ]
12
56951431-56959374
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038518" ]
[ "RODH-4", "SDR9C8" ]
[ "Enzymes", "Metabolic proteins", "Predicted membrane proteins" ]
[ "Lipid metabolism", "Steroid metabolism" ]
[ "Oxidoreductase" ]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 53: Liver - Plasma proteins
Tissue enriched
Detected in some
119
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
20
Cell type enriched
Detected in some
17
Not detected in immune cells
Not detected
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
7,720
1
ENSG00000139549
DHH
Desert hedgehog signaling molecule
[ "O43323" ]
12
49086656-49094801
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "HHG-3", "MGC35145" ]
[ "Disease related genes", "Human disease related genes", "Predicted secreted proteins" ]
[]
[ "Developmental protein", "Hydrolase", "Protease", "Transferase" ]
[ "Disease variant" ]
[]
[]
[ "Secreted in male reproductive system" ]
[ "Developmental protein" ]
null
null
null
30
null
null
null
Cluster 25: Non-specific - Transcription
Cluster 47: Leukemia - Hemostasis
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 67: Testis - Mixed function
Tissue enriched
Detected in single
11
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,721
2
ENSG00000139567
ACVRL1
Activin A receptor like type 1
[ "P37023" ]
12
51906908-51923361
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA007041" ]
[ "ACVRLK1", "ALK1", "HHT", "HHT2", "ORW2" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Angiogenesis" ]
[ "Kinase", "Receptor", "Serine/threonine-protein kinase", "Transferase" ]
[ "Disease variant" ]
[]
[]
[ "Intracellular and membrane" ]
[ "Receptor" ]
null
Approved
null
9
null
null
Cluster 26: Monocytes - Plasma membrane proteins
Cluster 47: Endothelial cells - Vasculature
Cluster 48: Adipocytes & Endothelial cells - Angiogenesis
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
19
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,722
3
ENSG00000139572
GPR84
G protein-coupled receptor 84
[ "Q9NQS5" ]
12
54362445-54364487
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA027603" ]
[ "EX33" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Enhanced
null
1
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 20: Macrophages & Microglia - Immune response
Cluster 71: Lymphoma - Inflammatory response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response
Tissue enhanced
Detected in some
null
Group enriched
Detected in some
6
Low cancer specificity
Detected in many
null
Group enriched
Detected in some
4
Group enriched
Detected in some
23
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,723
5
ENSG00000139574
NPFF
Neuropeptide FF-amide peptide precursor
[ "O15130" ]
12
53506688-53507484
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FMRFAL" ]
[ "Predicted secreted proteins" ]
[]
[ "Neuropeptide" ]
[]
[]
[]
[ "Secreted in male reproductive system" ]
[ "Neuropeptide" ]
null
null
null
null
null
null
null
Cluster 43: Hindbrain - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 30: Epididymal principal cells - Sperm storage microenvironment
Cluster 50: Epididymis - Male reproductive secretion
Tissue enriched
Detected in some
454
Cancer enriched
Detected in single
4
Cancer enriched
Detected in some
7
Cell type enriched
Detected in some
58
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,724
1
ENSG00000139579
NABP2
Nucleic acid binding protein 2
[ "Q9BQ15" ]
12
56222015-56229854
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044615", "HPA057213" ]
[ "hSSB1", "MGC2731", "OBFC2B", "SOSS-B1", "SSB1" ]
[ "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Supported
null
21
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 38: Non-specific - Transcription
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 19: Skeletal muscle - Striated muscle contraction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
5
Low immune cell specificity
Detected in all
null
4
0
4
[ "Glioblastoma Multiforme" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
7,725
1
ENSG00000139597
N4BP2L1
NEDD4 binding protein 2 like 1
[ "Q5TBK1" ]
13
32400723-32428311
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA038971", "HPA057219" ]
[ "CG018" ]
[ "Predicted intracellular proteins" ]
[]
[ "Developmental protein" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
null
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 51: Myeloma - Immunoglobulins
Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response
Cluster 31: Liver - Metabolism & Coagulation
Low tissue specificity
Detected in all
null
Group enriched
Detected in many
5
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
7,726
1
ENSG00000139610
CELA1
Chymotrypsin like elastase 1
[ "Q9UNI1" ]
12
51328442-51346679
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "ELA1" ]
[ "Enzymes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Hydrolase", "Protease", "Serine protease" ]
[]
[]
[]
[ "Secreted - unknown location" ]
[ "Enzyme" ]
null
null
null
null
null
null
Cluster 5: Non-specific - Cell proliferation
null
Cluster 34: Testis cancer - Unknown function
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 8: Pancreas - Proteolysis
Group enriched
Detected in some
5
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in many
null
0
0
0
[]
[]
[]
7,727
3
ENSG00000139613
SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
[ "Q8TAQ2" ]
12
56162359-56189567
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004321", "HPA021213", "HPA061788" ]
[ "BAF170", "CRACC2", "Rsc8" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Neurogenesis", "Transcription", "Transcription regulation" ]
[ "Chromatin regulator" ]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Supported
null
140
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 38: Non-specific - Transcription
Cluster 105: Non-specific - Mixed function
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
7,728
1
ENSG00000139618
BRCA2
BRCA2 DNA repair associated
[ "P51587" ]
13
32315086-32400268
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA026815" ]
[ "BRCC2", "FACD", "FAD", "FAD1", "FANCD", "FANCD1", "XRCC11" ]
[ "Cancer-related genes", "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cell cycle", "DNA damage", "DNA recombination", "DNA repair" ]
[ "DNA-binding" ]
[ "Cancer-related genes", "Disease variant", "Fanconi anemia", "Tumor suppressor" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Uncertain
null
83
Yes
No
Cluster 13: Non-specific - Mitochondria
null
Cluster 19: Non-specific - Unknown function
Cluster 27: Non-specific - Cell proliferation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
7,729
1
ENSG00000139620
KANSL2
KAT8 regulatory NSL complex subunit 2
[ "Q9H9L4" ]
12
48653211-48682238
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038497", "HPA038498" ]
[ "C12orf41", "FLJ20436", "NSL2" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[ "Chromatin regulator" ]
[]
[ "Nucleoplasm", "Plasma membrane", "Cytosol" ]
[]
[ "Intracellular and membrane" ]
[ "Other" ]
Supported
Uncertain
null
13
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 55: Non-specific - Transcription
Cluster 38: Non-specific - Transcription
Cluster 20: Non-specific - Transcription regulation
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
7,730
1
ENSG00000139624
CERS5
Ceramide synthase 5
[ "Q8N5B7" ]
12
50129289-50167533
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA006780", "HPA026589" ]
[ "FLJ25304", "LASS5", "MGC45411", "Trh4" ]
[ "Enzymes", "Metabolic proteins", "Predicted membrane proteins" ]
[ "Lipid biosynthesis", "Lipid metabolism", "Sphingolipid metabolism" ]
[ "Transferase" ]
[]
[ "Nuclear membrane" ]
[ "Endoplasmic reticulum", "Primary cilium" ]
[]
[]
Approved
Approved
null
2
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 25: Non-specific - Transcription
Cluster 35: RS4;11 - Unknown function
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Lung Squamous Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
7,731
1
ENSG00000139625
MAP3K12
Mitogen-activated protein kinase kinase kinase 12
[ "Q12852" ]
12
53479669-53500063
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039936", "HPA071996" ]
[ "DLK", "MEKK12", "MUK", "ZPK", "ZPKP1" ]
[ "Enzymes", "Predicted intracellular proteins", "Transporters" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nucleoplasm", "Plasma membrane" ]
[]
[]
[]
Approved
Enhanced
null
8
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 5: Rhabdoid - Unknown function
Cluster 83: Epicardial mesothelial cells - Basic cellular functions
Cluster 64: Non-specific - Transcription
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
3
0
3
[ "Lung Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
7,732
3
ENSG00000139626
ITGB7
Integrin subunit beta 7
[ "P26010" ]
12
53191323-53207282
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042277" ]
[]
[ "Cancer-related genes", "FDA approved drug targets", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[ "Host cell receptor for virus entry", "Integrin", "Receptor" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
null
null
3
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 20: Macrophages & Microglia - Immune response
Cluster 51: Myeloma - Immunoglobulins
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in many
18
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
4
0
4
[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
7,733
5
ENSG00000139629
GALNT6
Polypeptide N-acetylgalactosaminyltransferase 6
[ "Q8NCL4" ]
12
51351247-51392867
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011762", "HPA017086" ]
[ "GalNAc-T6" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Glycosyltransferase", "Transferase" ]
[]
[ "Nucleoplasm", "Golgi apparatus" ]
[]
[]
[]
Approved
Enhanced
null
11
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 68: Foveolar cells - Mucosal defense
Cluster 60: Stomach - Digestion
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
2
0
2
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma", "Ovary Serous Cystadenocarcinoma" ]
7,734
9
ENSG00000139631
CSAD
Cysteine sulfinic acid decarboxylase
[ "Q9Y600" ]
12
53157663-53180925
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039487", "HPA079296" ]
[ "CSD", "PCAP" ]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Decarboxylase", "Lyase" ]
[]
[ "Endoplasmic reticulum", "Vesicles", "Plasma membrane" ]
[]
[]
[]
Approved
Approved
null
1
null
null
Cluster 20: Non-specific - DNA binding
Cluster 11: White matter - Signal transduction
Cluster 27: Breast cancer - Unknown function
Cluster 89: Adipocytes - Lipid metabolism
Cluster 31: Liver - Metabolism & Coagulation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
4
3
2
3
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
7,735
7
ENSG00000139636
LMBR1L
Limb development membrane protein 1 like
[ "Q6UX01" ]
12
49097136-49110900
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FLJ10494", "KIAA1174" ]
[ "Essential proteins", "Predicted membrane proteins" ]
[ "Endocytosis", "Wnt signaling pathway" ]
[ "Receptor" ]
[]
[]
[]
[]
[]
null
null
null
9
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 25: Non-specific - Transcription
Cluster 46: Lymphoma - Humoral immune response
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
7,736
9
ENSG00000139637
MYG1
MYG1 exonuclease
[ "Q9HB07" ]
12
53299695-53307177
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038626", "HPA038627" ]
[ "C12orf10", "Gamm1", "MYG" ]
[ "Disease related genes", "Essential proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Nuclease" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
Supported
37
null
null
Cluster 33: Non-specific - ATP binding
Cluster 45: Non-specific - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
7,737
3
ENSG00000139641
ESYT1
Extended synaptotagmin 1
[ "Q9BSJ8" ]
12
56118250-56144674
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016858", "HPA076926" ]
[ "FAM62A", "KIAA0747", "MBC2" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Lipid transport", "Transport" ]
[]
[]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Supported
Approved
null
114
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 49: Hindbrain - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 58: Mast cells - Allergic inflammatory responses
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,738
5
ENSG00000139644
TMBIM6
Transmembrane BAX inhibitor motif containing 6
[ "P55061" ]
12
49707725-49764934
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA017378" ]
[ "BAXI1", "BI-1", "TEGT" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Apoptosis", "Autophagy", "Unfolded protein response" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
74
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 39: Astrocytes - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 16: Liver & Kidney - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Head and Neck Squamous Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
7,739
8
ENSG00000139648
KRT71
Keratin 71
[ "Q3SY84" ]
12
52543909-52553145
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049404" ]
[ "K6IRS1", "KRT6IRS", "KRT6IRS1" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Hypotrichosis" ]
[]
[]
[]
[]
null
Enhanced
null
23
null
null
null
null
Cluster 65: Non-specific - Unknown function
Cluster 30: Epididymal principal cells - Sperm storage microenvironment
Cluster 9: Skin - Hair follicle development
Tissue enriched
Detected in some
22
Not detected
Not detected
null
Cancer enriched
Detected in single
7
Cell type enriched
Detected in single
17
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,741
1
ENSG00000139651
ZNF740
Zinc finger protein 740
[ "Q8NDX6" ]
12
53180704-53195142
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA035691" ]
[ "Zfp740" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
1
null
null
Cluster 41: Basophils - Unknown function
Cluster 25: Non-specific - Transcription
Cluster 51: Myeloma - Immunoglobulins
Cluster 89: Adipocytes - Lipid metabolism
Cluster 49: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Low immune cell specificity
Detected in some
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,742
3
ENSG00000139656
SMIM2
Small integral membrane protein 2
[ "Q9BVW6" ]
13
44143150-44161257
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA026891", "HPA077071" ]
[ "C13orf44", "MGC5590" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[ "Nucleoplasm", "Nuclear bodies" ]
[]
[]
[]
Uncertain
Enhanced
null
2
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in some
5
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in some
null
Group enriched
Detected in some
7
Not detected in immune cells
Not detected
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,743
3
ENSG00000139668
WDFY2
WD repeat and FYVE domain containing 2
[ "Q96P53" ]
13
51584455-51767709
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA050094" ]
[ "ZFYVE22" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Supported
null
null
6
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 13: Oligodendrocytes - Mixed function
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 58: Skin - Keratinization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
7,744
5
ENSG00000139675
HNRNPA1L2
Heterogeneous nuclear ribonucleoprotein A1 like 2
[ "Q32P51" ]
13
52642431-52643773
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA077520" ]
[ "LOC144983" ]
[ "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing", "mRNA transport", "Transport" ]
[ "Ribonucleoprotein", "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
9
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 16: Non-specific - Transcription
Cluster 19: Non-specific - Unknown function
Cluster 105: Non-specific - Mixed function
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Bladder Urothelial Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
7,745
5
ENSG00000139679
LPAR6
Lysophosphatidic acid receptor 6
[ "P43657" ]
13
48389567-48444704
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028934", "HPA076273" ]
[ "P2RY5", "P2Y5" ]
[ "Disease related genes", "G-protein coupled receptors", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[ "Disease variant", "Hypotrichosis" ]
[ "Plasma membrane" ]
[ "Vesicles" ]
[]
[]
Supported
Approved
null
9
null
null
Cluster 33: Non-specific - ATP binding
Cluster 20: Macrophages & Microglia - Immune response
Cluster 6: Leukemia - Signal transduction
Cluster 74: Microglia - Neuroimmunity & neuroinflammation
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
7,746
9
ENSG00000139687
RB1
RB transcriptional corepressor 1
[ "P06400" ]
13
48303744-48599436
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB000095", "CAB016687", "HPA050082" ]
[ "OSRC", "PPP1R130", "RB" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Host-virus interaction", "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "DNA-binding", "Repressor" ]
[ "Cancer-related genes", "Disease variant", "Tumor suppressor" ]
[ "Nucleoplasm" ]
[ "Primary cilium transition zone" ]
[]
[]
Supported
Supported
null
218
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 55: Non-specific - Transcription
Cluster 19: Non-specific - Unknown function
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
7,748
2
ENSG00000139697
SBNO1
Strawberry notch homolog 1
[ "A3KN83" ]
12
123289109-123364847
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042388" ]
[ "FLJ10701", "FLJ10833", "MOP3", "Sno" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Inflammatory response", "Wnt signaling pathway" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
null
null
null
Cluster 24: Non-specific - Transcription
Cluster 34: Non-specific - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 44: Bone marrow - Nuclear processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
7,749
3
ENSG00000139714
MORN3
MORN repeat containing 3
[ "Q6PF18" ]
12
121648742-121672631
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA038709", "HPA038710" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Plasma membrane" ]
[]
[]
Approved
Uncertain
null
59
null
null
Cluster 20: Non-specific - DNA binding
Cluster 17: Choroid plexus - Cilium
Cluster 34: Testis cancer - Unknown function
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 1: Choroid plexus - Transmembrane transport
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in many
7
Low immune cell specificity
Detected in some
null
2
0
2
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Papillary Cell Carcinoma" ]
7,750
4
ENSG00000139719
VPS33A
VPS33A core subunit of CORVET and HOPS complexes
[ "Q96AX1" ]
12
122229564-122266494
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038701" ]
[]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Autophagy", "Protein transport", "Transport" ]
[]
[ "Disease variant", "Mucopolysaccharidosis" ]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
48
null
null
Cluster 9: T-regs - Cell cycle regulation
Cluster 34: Non-specific - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 22: Non-specific - Basic cellular functions
Cluster 32: Retina & Lymphoid tissues - Signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in some
7
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
7,752
7
ENSG00000139722
VPS37B
VPS37B subunit of ESCRT-I
[ "Q9H9H4" ]
12
122865330-122896127
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038217", "HPA038218" ]
[ "FLJ12750" ]
[ "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[]
[]
[ "Cytosol" ]
[ "Primary cilium" ]
[]
[]
Uncertain
Enhanced
null
47
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 51: Neurons - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 103: Non-specific - Basic cellular processes
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,753
5
ENSG00000139725
RHOF
Ras homolog family member F, filopodia associated
[ "Q9HBH0" ]
12
121777754-121803403
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045912", "HPA076019" ]
[ "ARHF", "FLJ20247", "RIF" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Golgi apparatus" ]
[]
[]
[]
Approved
Enhanced
Supported
8
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 34: Lymphoid tissue - Adaptive immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
6
0
6
[ "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
7,754
1
ENSG00000139726
DENR
Density regulated re-initiation and release factor
[ "O43583" ]
12
122752824-122771064
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA021783" ]
[ "DRP", "DRP1", "SMAP-3" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Protein biosynthesis" ]
[ "Initiation factor" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
8
null
null
Cluster 41: Basophils - Unknown function
Cluster 1: Neurons - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 17: Non-specific - RNA processing
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Immune cell enhanced
Detected in all
null
3
2
2
[]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
7,755
1
ENSG00000139734
DIAPH3
Diaphanous related formin 3
[ "Q9NSV4" ]
13
59665583-60163928
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA032151" ]
[ "AN", "AUNA1", "DRF3", "FLJ34705", "NSDAN" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Cancer-related genes", "Deafness", "Neuropathy", "Non-syndromic deafness" ]
[ "Plasma membrane", "Microtubules" ]
[]
[]
[]
Supported
null
null
8
null
Yes
null
null
Cluster 19: Non-specific - Unknown function
Cluster 27: Non-specific - Cell proliferation
Cluster 39: Testis - Nuclear processes
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
5
2
4
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
7,756
6
ENSG00000139737
SLAIN1
SLAIN motif family member 1
[ "Q8ND83" ]
13
77697687-77764242
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "C13orf32", "FLJ30046" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
36
null
null
Cluster 1: T-cells - Unknown function
Cluster 11: White matter - Signal transduction
Cluster 6: Leukemia - Signal transduction
Cluster 80: Oligodendrocytes - Myelination
Cluster 3: Oligodendrocytes - Myelination
Tissue enriched
Detected in all
6
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in all
4
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
2
0
2
[ "Breast Invasive Carcinoma" ]
[ "Prostate Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Prostate Adenocarcinoma" ]
7,757
9
ENSG00000139746
RBM26
RNA binding motif protein 26
[ "Q5T8P6" ]
13
79311824-79406477
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA040252" ]
[ "ARRS2", "C13orf10", "FLJ20957", "PPP1R132", "PRO1777", "SE70-2", "ZC3H17" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "RNA-binding" ]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Approved
Approved
null
17
null
null
Cluster 32: Basophils - Transcription
Cluster 31: Non-specific - Transcription
Cluster 19: Non-specific - Unknown function
Cluster 7: Non-specific - Transcription
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
7,758
6
ENSG00000139767
SRRM4
Serine/arginine repetitive matrix 4
[ "A7MD48" ]
12
118981541-119163051
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA052783" ]
[ "KIAA1853", "nSR100" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "mRNA processing", "mRNA splicing" ]
[ "RNA-binding" ]
[]
[]
[]
[]
[]
null
Uncertain
null
31
null
null
null
Cluster 37: Neurons - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 46: Brain & retina - Neuronal signaling
Group enriched
Detected in some
26
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in single
6
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,759
3
ENSG00000139780
METTL21C
Methyltransferase 21C, AARS1 lysine
[ "Q5VZV1" ]
13
102685747-102695044
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "C13orf39", "LOC196541" ]
[ "Predicted intracellular proteins" ]
[]
[ "Methyltransferase", "Transferase" ]
[]
[]
[]
[]
[]
null
null
null
3
null
null
null
Cluster 4: Non-specific - mRNA splicing & Cell cycle
Cluster 5: Rhabdoid - Unknown function
Cluster 30: Epididymal principal cells - Sperm storage microenvironment
Cluster 22: Epididymis - Mixed function
Tissue enriched
Detected in some
6
Not detected
Not detected
null
Cancer enriched
Detected in single
5
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,760
8
ENSG00000139793
MBNL2
Muscleblind like splicing regulator 2
[ "Q5VZF2" ]
13
97221434-97394120
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA062685" ]
[ "MBLL", "MBLL39" ]
[ "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[ "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
null
null
1
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 28: Oligodendrocytes - Mixed function
Cluster 19: Non-specific - Unknown function
Cluster 44: Plasma cells - Antibody production & secretion
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Colon Adenocarcinoma", "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
7,761
5
ENSG00000139797
RNF113B
Ring finger protein 113B
[ "Q8IZP6" ]
13
98175785-98177269
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "RNF161", "ZNF183L1" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in single
173
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
7
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,762
9
ENSG00000139800
ZIC5
Zic family member 5
[ "Q96T25" ]
13
99962964-99971767
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA074045" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Differentiation", "Neurogenesis" ]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm", "Vesicles" ]
[]
[]
[]
Uncertain
null
null
null
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 10: Ciliated cells - Ion channel activity
Cluster 2: Cerebellar granular cells - Neuronal signaling
Cluster 71: Cerebellum - Nervous system development
Tissue enriched
Detected in some
5
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in some
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,763
5
ENSG00000139826
ABHD13
Abhydrolase domain containing 13
[ "Q7L211" ]
13
108218392-108234243
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA032143", "HPA032144" ]
[ "bA153I24.2", "BEM46L1", "C13orf6", "FLJ14906" ]
[ "Predicted membrane proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
null
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 31: Non-specific - Transcription
Cluster 19: Non-specific - Unknown function
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,764
7
ENSG00000139835
GRTP1
Growth hormone regulated TBC protein 1
[ "Q5TC63" ]
13
113324163-113364148
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046201" ]
[ "FLJ22474", "TBC1D6" ]
[ "Predicted intracellular proteins" ]
[]
[ "GTPase activation" ]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 12: Non-specific - Vasculature
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 26: Kidney & Intestine - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
7,766
6
ENSG00000139842
CUL4A
Cullin 4A
[ "Q13619" ]
13
113208193-113267108
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA058979" ]
[]
[ "Predicted intracellular proteins" ]
[ "Biological rhythms", "DNA damage", "DNA repair", "Host-virus interaction", "Ubl conjugation pathway" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
155
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 12: Non-specific - Vasculature
Cluster 19: Non-specific - Unknown function
Cluster 17: Non-specific - RNA processing
Cluster 63: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,767
1
ENSG00000139865
TTC6
Tetratricopeptide repeat domain 6
[ "Q86TZ1" ]
14
37595629-38041442
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA069293" ]
[ "C14orf25", "NCRNA00291" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Centrosome" ]
[ "Basal body" ]
[]
[]
Approved
null
null
null
null
null
null
Cluster 46: Brainstem - Mixed function
Cluster 60: Prostate cancer - Unknown function
Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid
Cluster 21: Testis - Mixed function
Tissue enhanced
Detected in some
null
Cancer enriched
Detected in some
4
Group enriched
Detected in many
5
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,768
9
ENSG00000139874
SSTR1
Somatostatin receptor 1
[ "P30872" ]
14
38207904-38213067
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003207", "HPA031506" ]
[]
[ "FDA approved drug targets", "G-protein coupled receptors", "Predicted membrane proteins", "Transporters" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[ "FDA approved drug targets" ]
[ "Vesicles" ]
[]
[]
[]
Uncertain
Approved
null
9
null
null
null
Cluster 24: Neurons - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
7,769
5
ENSG00000139880
CDH24
Cadherin 24
[ "Q86UP0" ]
14
23047062-23057538
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA074551" ]
[ "CDH11L" ]
[ "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[]
[ "Cytosol" ]
[ "Vesicles" ]
[]
[]
Approved
null
null
null
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
7,770
7
ENSG00000139890
REM2
RRAD and GEM like GTPase 2
[ "Q8IYK8" ]
14
22883222-22887678
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FLJ38964" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
2
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
0
1
[ "Pancreatic Adenocarcinoma" ]
[]
[ "Pancreatic Adenocarcinoma" ]
7,771
5
ENSG00000139908
TSSK4
Testis specific serine kinase 4
[ "Q6SA08" ]
14
24205696-24208362
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA060660", "HPA077103" ]
[ "C14orf20", "STK22E" ]
[ "Enzymes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[ "Developmental protein", "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Cell Junctions" ]
[]
[]
[]
Uncertain
Approved
null
1
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 56: Non-specific - Sensory perception
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 47: Testis - Mixed function
Tissue enriched
Detected in many
9
Low cancer specificity
Detected in many
null
Not detected
Not detected
null
Group enriched
Detected in some
17
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,773
6
ENSG00000139910
NOVA1
NOVA alternative splicing regulator 1
[ "P51513" ]
14
26443090-26598033
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA004155" ]
[ "NOVA-1" ]
[ "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing", "Neurogenesis" ]
[ "RNA-binding" ]
[]
[ "Nucleoli" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Uncertain
null
4
null
null
null
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 27: Breast cancer - Unknown function
Cluster 14: Oligodendrocyte progenitor cells - Development & myelination
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enriched
Detected in many
5
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Pancreatic Adenocarcinoma" ]
[]
[ "Pancreatic Adenocarcinoma" ]
7,774
8
ENSG00000139914
FITM1
Fat storage inducing transmembrane protein 1
[ "A5D6W6" ]
14
24130659-24132849
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA019842" ]
[ "FIT1" ]
[ "Metabolic proteins", "Predicted membrane proteins" ]
[ "Lipid metabolism" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 25: Non-specific - Transcription
Cluster 33: Sarcoma - Muscle contraction
Cluster 102: Non-specific - Mixed function
Cluster 52: Non-specific - Cellular respiration
Group enriched
Detected in many
7
Low cancer specificity
Detected in single
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,775
8
ENSG00000139915
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
[ "Q7Z553" ]
14
46839629-47675605
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003084" ]
[ "MAMDC1" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 24: Neurons - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 46: Brain & retina - Neuronal signaling
Group enriched
Detected in some
10
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
7,776
3
ENSG00000139921
TMX1
Thioredoxin related transmembrane protein 1
[ "Q9H3N1" ]
14
51240162-51257655
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003085" ]
[ "PDIA11", "TMX", "TXNDC", "TXNDC1" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Electron transport", "Transport" ]
[ "Isomerase" ]
[]
[ "Endoplasmic reticulum" ]
[ "Nucleoli" ]
[ "Intracellular and membrane" ]
[ "Transport" ]
Supported
Approved
null
51
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 44: Non-specific - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 97: Non-specific - Cellular respiration
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
7,777
3
ENSG00000139926
FRMD6
FERM domain containing 6
[ "Q96NE9" ]
14
51489100-51730727
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001297" ]
[ "C14orf31", "EX1", "MGC17921", "willin" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
Uncertain
Supported
28
null
null
null
Cluster 16: Non-specific - Transcription
Cluster 64: Connective tissue cells - ECM organization
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 81: Squamous epithelium - Keratinization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma", "Stomach Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma", "Stomach Adenocarcinoma" ]
7,778
7
ENSG00000139946
PELI2
Pellino E3 ubiquitin protein ligase family member 2
[ "Q9HAT8" ]
14
56117814-56301524
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA053182" ]
[]
[ "Enzymes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Nucleoplasm", "Nucleoli", "Basal body" ]
[ "Intermediate filaments", "Centriolar satellite", "Centrosome", "Cytosol" ]
[]
[]
Approved
Uncertain
null
29
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 25: Non-specific - Transcription
Cluster 24: Non-specific - Unknown function
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 8: Pancreas - Proteolysis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
7,779
4
ENSG00000139970
RTN1
Reticulon 1
[ "Q16799" ]
14
59595976-59870776
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002745", "HPA040945", "HPA044249" ]
[ "NSP" ]
[ "Plasma proteins", "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[ "Endoplasmic reticulum" ]
[ "Nuclear bodies" ]
[]
[]
Supported
Enhanced
null
10
null
null
Cluster 26: Monocytes - Plasma membrane proteins
Cluster 14: Neurons - Synaptic function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 27: Cerebellum - Synaptic function
Tissue enriched
Detected in many
7
Cancer enriched
Detected in many
7
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
6
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
7,780
9
ENSG00000139973
SYT16
Synaptotagmin 16
[ "Q17RD7" ]
14
61811974-62112550
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA004199", "HPA076871" ]
[ "CHR14SYT", "Strep14", "SYT14L", "yt14r" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
26
null
null
null
Cluster 14: Neurons - Synaptic function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 73: Brain - Neuronal signaling
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in single
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,782
9
ENSG00000139977
NAA30
N-alpha-acetyltransferase 30, NatC catalytic subunit
[ "Q147X3" ]
14
57390544-57415906
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA057824" ]
[ "C14orf35", "FLJ35355", "MAK3", "Mak3p", "NAT12" ]
[ "Enzymes", "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Acyltransferase", "Transferase" ]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Uncertain
null
2
null
null
Cluster 16: Non-specific - Cell proliferation
Cluster 14: Neurons - Synaptic function
Cluster 30: Non-specific - Gene expression regulation
Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
7,784
6
ENSG00000139985
ADAM21
ADAM metallopeptidase domain 21
[ "Q9UKJ8" ]
14
70417107-70460427
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA059016" ]
[ "ADAM31" ]
[ "Predicted membrane proteins" ]
[]
[ "Hydrolase", "Metalloprotease", "Protease" ]
[]
[]
[]
[]
[]
null
Uncertain
null
24
null
null
null
Cluster 32: Cerebral cortex - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 89: Adipocytes - Lipid metabolism
Cluster 6: Testis - Spermatogenesis
Tissue enriched
Detected in some
7
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,785
6
ENSG00000139988
RDH12
Retinol dehydrogenase 12
[ "Q96NR8" ]
14
67701886-67734451
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FLJ30273", "LCA13", "RP53", "SDR7C2" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Lipid metabolism", "Sensory transduction", "Vision" ]
[ "Oxidoreductase" ]
[ "Disease variant", "Leber congenital amaurosis", "Retinitis pigmentosa" ]
[]
[]
[]
[]
null
null
null
9
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Group enriched
Detected in many
6
Low cancer specificity
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,786
3
ENSG00000139990
DCAF5
DDB1 and CUL4 associated factor 5
[ "Q96JK2" ]
14
69050881-69153150
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041575", "HPA048098" ]
[ "BCRG2", "BCRP2", "D14S1461E", "KIAA1824", "WDR22" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
Uncertain
null
37
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 30: Non-specific - Gene expression regulation
Cluster 7: Non-specific - Transcription
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
7,787
9
ENSG00000139998
RAB15
RAB15, member RAS oncogene family
[ "P59190" ]
14
64945814-64973226
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041177" ]
[]
[ "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[ "Hydrolase" ]
[]
[ "Vesicles", "Centriolar satellite" ]
[]
[]
[]
Approved
Uncertain
null
2
null
null
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
Cluster 51: Neurons - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
5
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
7,788
1
ENSG00000140006
WDR89
WD repeat domain 89
[ "Q96FK6" ]
14
63597039-63641871
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA000813" ]
[ "C14orf150", "MGC9907" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Intermediate filaments", "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
6
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 31: Non-specific - Transcription
Cluster 30: Non-specific - Gene expression regulation
Cluster 7: Non-specific - Transcription
Cluster 32: Retina & Lymphoid tissues - Signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,789
2
ENSG00000140009
ESR2
Estrogen receptor 2
[ "Q92731" ]
14
64084232-64338112
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA068406", "CAB079300" ]
[ "ER-beta", "Erb", "NR3A2" ]
[ "Cancer-related genes", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Nuclear receptors", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding", "Receptor" ]
[ "Cancer-related genes", "Disease variant", "FDA approved drug targets" ]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Supported
Enhanced
null
68
null
null
Cluster 30: Non-specific - DNA binding
Cluster 48: Non-specific - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 83: Epicardial mesothelial cells - Basic cellular functions
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
0
0
0
[]
[]
[]
7,790
3
ENSG00000140015
KCNH5
Potassium voltage-gated channel subfamily H member 5
[ "Q8NCM2" ]
14
62699464-63102037
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA030487", "HPA072351" ]
[ "eag2", "H-EAG2", "hEAG2", "Kv10.2" ]
[ "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Ion transport", "Potassium transport", "Transport" ]
[ "Calmodulin-binding", "Ion channel", "Potassium channel", "Voltage-gated channel" ]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[ "Centrosome" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
Approved
Uncertain
null
1
null
null
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,791
1
ENSG00000140022
STON2
Stonin 2
[ "Q8WXE9" ]
14
81260652-81436465
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003086" ]
[ "STN2", "STNB2" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Endocytosis" ]
[]
[]
[ "Nucleoli", "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
15
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 47: Leukemia - Hemostasis
Cluster 47: Platelets - Hemostasis
Cluster 78: Brain - Neuronal signaling
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,792
5
ENSG00000140025
EFCAB11
EF-hand calcium binding domain 11
[ "Q9BUY7" ]
14
89794669-89954777
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA051209" ]
[ "C14orf143" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cell Junctions", "Cytosol" ]
[]
[]
[]
Approved
null
null
7
null
null
Cluster 25: Non-specific - Unknown function
Cluster 46: Brainstem - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 67: Testis - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
7
Immune cell enhanced
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,793
4
ENSG00000140030
GPR65
G protein-coupled receptor 65
[ "Q8IYL9" ]
14
88005135-88014811
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA072624", "HPA077397" ]
[ "hTDAG8", "TDAG8" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Apoptosis" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[ "Vesicles" ]
[ "Nucleoli", "Cytosol" ]
[]
[]
Approved
Enhanced
null
1
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 20: Macrophages & Microglia - Immune response
Cluster 59: Leukemia - T-cell receptor
Cluster 58: Mast cells - Allergic inflammatory responses
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Group enriched
Detected in some
6
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
7,794
2
ENSG00000140044
JDP2
Jun dimerization protein 2
[ "Q8WYK2" ]
14
75427716-75474111
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA059511" ]
[ "JUNDM2" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[]
[ "Nucleoplasm", "Nuclear speckles" ]
[]
[]
[]
Approved
Supported
null
14
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 47: Endothelial cells - Vasculature
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
7,796
7
ENSG00000140057
AK7
Adenylate kinase 7
[ "Q96M32" ]
14
96392128-96489427
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003543" ]
[ "CFAP75", "FAP75", "FLJ32864" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation" ]
[ "Kinase", "Transferase" ]
[ "Disease variant" ]
[ "Cytosol", "Principal piece" ]
[]
[]
[]
Supported
Enhanced
null
null
null
null
Cluster 46: Basophils - Proteolysis
Cluster 3: Choroid plexus - Cilium
Cluster 12: Bone cancer - Neuronal signaling
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
24
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
7,797
8
ENSG00000140067
FAM181A
Family with sequence similarity 181 member A
[ "Q8N9Y4" ]
14
93918894-93929608
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001603", "HPA018522" ]
[ "C14orf152" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
null
null
null
null
Cluster 39: Astrocytes - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 67: Testis - Mixed function
Group enriched
Detected in some
9
Not detected
Not detected
null
Group enriched
Detected in some
6
Group enriched
Detected in some
16
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,798
6
ENSG00000140090
SLC24A4
Solute carrier family 24 member 4
[ "Q8NFF2" ]
14
92322581-92501481
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA063206" ]
[ "NCKX4" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Antiport", "Calcium transport", "Ion transport", "Olfaction", "Potassium transport", "Sensory transduction", "Sodium transport", "Symport", "Transport" ]
[]
[ "Amelogenesis imperfecta", "Disease variant" ]
[ "Plasma membrane" ]
[]
[]
[]
Approved
null
null
null
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 42: Choroid plexus - Mitochondria
Cluster 54: Non-specific - Transcription
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 1: Choroid plexus - Transmembrane transport
Group enriched
Detected in some
6
Group enriched
Detected in some
10
Cancer enhanced
Detected in some
null
Group enriched
Detected in many
8
Group enriched
Detected in some
4
0
0
0
[]
[]
[]
7,799
8
ENSG00000140092
FBLN5
Fibulin 5
[ "Q9UBX5" ]
14
91869411-91947987
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000848", "HPA000868", "CAB025843" ]
[ "ARMD3", "DANCE", "EVEC", "UP50" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Cell adhesion" ]
[]
[ "Age-related macular degeneration", "Charcot-Marie-Tooth disease", "Disease variant", "Neurodegeneration", "Neuropathy" ]
[ "Plasma membrane" ]
[]
[ "Secreted to extracellular matrix" ]
[ "Cell adhesion" ]
Uncertain
Supported
null
16
null
null
Cluster 41: Basophils - Unknown function
Cluster 39: Astrocytes - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in all
null
Group enriched
Detected in many
7
Immune cell enhanced
Detected in some
null
2
2
1
[ "Liver Hepatocellular Carcinoma" ]
[ "Stomach Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Stomach Adenocarcinoma" ]
7,800
4
ENSG00000140093
SERPINA10
Serpin family A member 10
[ "Q9UK55" ]
14
94280460-94293268
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA048739" ]
[ "PZI", "ZPI" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Blood coagulation", "Hemostasis" ]
[ "Heparin-binding", "Protease inhibitor", "Serine protease inhibitor" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[ "Secreted to blood" ]
[ "Blood coagulation" ]
Approved
null
null
8
null
null
null
Cluster 9: Non-specific - Receptor signaling
Cluster 10: Ciliated cells - Ion channel activity
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 53: Liver - Plasma proteins
Tissue enriched
Detected in some
112
Low cancer specificity
Detected in many
null
Cancer enriched
Detected in some
40
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Stomach Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma", "Stomach Adenocarcinoma" ]
7,801
1
ENSG00000140104
CLBA1
Clathrin binding box of aftiphilin containing 1
[ "Q96F83" ]
14
104985775-105010482
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA042052", "HPA061117", "HPA078556" ]
[ "C14orf79" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
Approved
Approved
null
null
null
null
null
Cluster 17: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,802
3
ENSG00000140105
WARS1
Tryptophanyl-tRNA synthetase 1
[ "P23381" ]
14
100333790-100376805
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA005573", "HPA018944" ]
[ "IFI53", "IFP53", "WARS" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Angiogenesis", "Protein biosynthesis" ]
[ "Aminoacyl-tRNA synthetase", "Ligase" ]
[ "Intellectual disability", "Neurodegeneration", "Neuropathy" ]
[ "Cytosol" ]
[]
[]
[]
Enhanced
Enhanced
null
9
No
No
Cluster 40: Monocytes - Innate immune response
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 13: Non-specific - Mixed function
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enhanced
Detected in all
null
0
0
0
[]
[]
[]
7,803
7
ENSG00000140107
SLC25A47
Solute carrier family 25 member 47
[ "Q6Q0C1" ]
14
100323339-100330421
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "C14orf68", "HDCMP" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
Cluster 10: Ciliated cells - Ion channel activity
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 31: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
357
Not detected
Not detected
null
Cancer enriched
Detected in single
204
Cell type enriched
Detected in some
42
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,804
7