ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000140153 | WDR20 | WD repeat domain 20 | [
"Q8TBZ3"
] | 14 | 102139503-102224847 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"Bun107",
"DMR",
"FLJ33659",
"MGC33177"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | 21 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 11: White matter - Signal transduction | Cluster 30: Non-specific - Gene expression regulation | Cluster 7: Non-specific - Transcription | Cluster 47: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 7,805 | 5 |
ENSG00000140157 | NIPA2 | NIPA magnesium transporter 2 | [
"Q8N8Q9"
] | 15 | 22838644-22869362 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA067160",
"HPA071342"
] | [
"SLC57A2"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 21: Non-specific - Metabolism | Cluster 58: Non-specific - Nuclear processes | Cluster 102: Non-specific - Mixed function | Cluster 34: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 7,806 | 1 |
ENSG00000140199 | SLC12A6 | Solute carrier family 12 member 6 | [
"Q9UHW9"
] | 15 | 34229784-34338060 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA034563"
] | [
"ACCPN",
"KCC3",
"KCC3A",
"KCC3B"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Potassium transport",
"Symport",
"Transport"
] | [] | [
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 26 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 26: Oligodendrocytes - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 32: Retina & Lymphoid tissues - Signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Group enriched | Detected in many | 6 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 7,807 | 7 |
ENSG00000140259 | MFAP1 | Microfibril associated protein 1 | [
"P55081"
] | 15 | 43804492-43824690 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015583",
"HPA042370"
] | [
"AMP"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Nucleoplasm"
] | [
"Centrosome"
] | [] | [] | Supported | Uncertain | null | 139 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 16: Non-specific - Transcription | Cluster 58: Non-specific - Nuclear processes | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 4 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,809 | 1 |
ENSG00000140262 | TCF12 | Transcription factor 12 | [
"Q99081"
] | 15 | 56918623-57299281 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004432",
"HPA065827"
] | [
"bHLHb20",
"HEB",
"HsT17266",
"HTF4",
"p64"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes",
"Craniosynostosis",
"Disease variant",
"Hypogonadotropic hypogonadism",
"Kallmann syndrome"
] | [
"Nucleoplasm",
"Nuclear speckles"
] | [] | [] | [] | Supported | Approved | null | 69 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 13: Oligodendrocytes - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 80: Oligodendrocytes - Myelination | Cluster 80: Thymus - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Bladder Urothelial Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma"
] | 7,810 | 3 |
ENSG00000140263 | SORD | Sorbitol dehydrogenase | [
"Q00796"
] | 15 | 45023147-45077185 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040260",
"HPA040621"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [
"Disease variant",
"Neuropathy"
] | [
"Cytosol"
] | [
"Acrosome",
"Equatorial segment"
] | [] | [] | Approved | Enhanced | null | 6 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 15: Non-specific - Transcription | Cluster 60: Prostate cancer - Unknown function | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in all | 4 | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 11 | 1 | 0 | 1 | [
"Lung Squamous Cell Carcinoma"
] | [] | [
"Lung Squamous Cell Carcinoma"
] | 7,811 | 3 |
ENSG00000140265 | ZSCAN29 | Zinc finger and SCAN domain containing 29 | [
"Q8IWY8"
] | 15 | 43358172-43371043 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007241",
"HPA011109"
] | [
"FLJ35867",
"Zfp690",
"ZNF690"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Plasma membrane",
"Actin filaments"
] | [] | [] | Approved | Enhanced | null | 1 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 13: Oligodendrocytes - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Immune cell enhanced | Detected in some | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 7,813 | 5 |
ENSG00000140274 | DUOXA2 | Dual oxidase maturation factor 2 | [
"Q1HG44"
] | 15 | 45114326-45118421 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA063548"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [
"Protein transport",
"Transport"
] | [] | [
"Congenital hypothyroidism"
] | [] | [] | [] | [] | null | Enhanced | null | 21 | null | null | null | null | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 68: Foveolar cells - Mucosal defense | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,814 | 1 |
ENSG00000140279 | DUOX2 | Dual oxidase 2 | [
"Q9NRD8"
] | 15 | 45092650-45114172 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"LNOX2",
"P138-TOX",
"P138(TOX)",
"THOX2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Hydrogen peroxide",
"Thyroid hormones biosynthesis"
] | [
"Oxidoreductase",
"Peroxidase"
] | [
"Congenital hypothyroidism",
"Disease variant"
] | [] | [] | [] | [] | null | null | null | 1 | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 68: Foveolar cells - Mucosal defense | Cluster 13: Lung - Secretion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,815 | 5 |
ENSG00000140280 | LYSMD2 | LysM domain containing 2 | [
"Q8IV50"
] | 15 | 51723011-51751585 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040460"
] | [
"MGC35274"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [
"Nuclear bodies"
] | [] | [] | Approved | Approved | null | null | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 1: Neurons - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 10: Brain - Synaptic signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 7,816 | 8 |
ENSG00000140284 | SLC27A2 | Solute carrier family 27 member 2 | [
"O14975"
] | 15 | 50182196-50236385 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026089"
] | [
"ACSVL1",
"FACVL1",
"FATP2",
"hFACVL1",
"HsT17226",
"VLACS",
"VLCS"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Fatty acid metabolism",
"Lipid metabolism",
"Lipid transport",
"Transport"
] | [
"Ligase"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 42 | null | null | Cluster 41: Basophils - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 30 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,817 | 8 |
ENSG00000140285 | FGF7 | Fibroblast growth factor 7 | [
"P21781"
] | 15 | 49423237-49488775 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043605"
] | [
"KGF"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [] | [
"Growth factor",
"Heparin-binding",
"Mitogen"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [
"Secreted in other tissues"
] | [
"Growth factor"
] | Approved | Uncertain | null | 2 | null | null | null | Cluster 26: Oligodendrocytes - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 103: Non-specific - Basic cellular processes | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Thyroid Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Thyroid Carcinoma"
] | 7,818 | 8 |
ENSG00000140287 | HDC | Histidine decarboxylase | [
"P19113"
] | 15 | 50241947-50265965 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038891"
] | [] | [
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Catecholamine biosynthesis"
] | [
"Decarboxylase",
"Lyase"
] | [] | [
"Nuclear bodies"
] | [] | [] | [] | Approved | Enhanced | null | 1 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 49: HMC-1 - Innate immune response | Cluster 58: Mast cells - Allergic inflammatory responses | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 5 | Group enriched | Detected in some | 5 | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 2,147 | 0 | 0 | 0 | [] | [] | [] | 7,819 | 9 |
ENSG00000140297 | GCNT3 | Glucosaminyl (N-acetyl) transferase 3, mucin type | [
"O95395"
] | 15 | 59594875-59640239 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA011154"
] | [
"C2/4GnT",
"C2GnT-M",
"C2GnT2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [] | [
"Golgi apparatus"
] | [
"Vesicles"
] | [] | [] | Approved | Enhanced | null | 6 | null | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 7,820 | 5 |
ENSG00000140299 | BNIP2 | BCL2 interacting protein 2 | [
"Q12982"
] | 15 | 59659146-59689339 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026843"
] | [
"BNIP-2",
"Nip2"
] | [
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Cytosol"
] | [
"Nucleoli"
] | [] | [] | Supported | Approved | null | 41 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 44: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,821 | 9 |
ENSG00000140307 | GTF2A2 | General transcription factor IIA subunit 2 | [
"P52657"
] | 15 | 59638062-59657541 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044897",
"HPA077202"
] | [
"HsT18745",
"TFIIA"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | null | null | 16 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 55: Non-specific - Transcription | Cluster 58: Non-specific - Nuclear processes | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 7,822 | 8 |
ENSG00000140319 | SRP14 | Signal recognition particle 14 | [
"P37108"
] | 15 | 40035690-40039181 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053738",
"HPA065118"
] | [
"ALURBP",
"MGC14326"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [] | [
"Ribonucleoprotein",
"RNA-binding"
] | [] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Approved | null | null | 165 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 58: Non-specific - Nuclear processes | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,823 | 6 |
ENSG00000140320 | BAHD1 | Bromo adjacent homology domain containing 1 | [
"Q8TBE0"
] | 15 | 40439721-40468236 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041196"
] | [
"KIAA0945"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 65 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 51: Neurons - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 81: Alveolar cells - Lung function | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 7,824 | 6 |
ENSG00000140323 | DISP2 | Dispatched RND transporter family member 2 | [
"A7MBM2"
] | 15 | 40358219-40378621 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA059903"
] | [
"C15orf36",
"DISPB",
"HsT16908",
"KIAA1742",
"LINC00594"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in some | 17 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | 7,825 | 9 |
ENSG00000140326 | CDAN1 | Codanin 1 | [
"Q8IWY9"
] | 15 | 42723544-42737128 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039404",
"HPA040787"
] | [
"CDA-I",
"CDAI"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [
"Congenital dyserythropoietic anemia",
"Disease variant",
"Hereditary hemolytic anemia"
] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Enhanced | Supported | null | 8 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 48: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 7,826 | 2 |
ENSG00000140350 | ANP32A | Acidic nuclear phosphoprotein 32 family member A | [
"P39687"
] | 15 | 68778535-68820897 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005231",
"HPA063133",
"HPA067561"
] | [
"C15orf1",
"I1PP2A",
"LANP",
"MAPM",
"mapmodulin",
"PHAPI",
"PP32"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [] | [
"Nucleoplasm"
] | [
"Centrosome",
"Cytosol"
] | [] | [] | Supported | Supported | null | 27 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 51: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 7,828 | 5 |
ENSG00000140365 | COMMD4 | COMM domain containing 4 | [
"Q9H0A8"
] | 15 | 75336020-75343224 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039935",
"HPA066957"
] | [
"FLJ20452"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway"
] | [] | [] | [
"Cytosol"
] | [
"Vesicles",
"Plasma membrane"
] | [] | [] | Supported | Uncertain | null | 92 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 21: Non-specific - Metabolism | Cluster 58: Non-specific - Nuclear processes | Cluster 27: Non-specific - Cell proliferation | Cluster 56: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 7,829 | 9 |
ENSG00000140367 | UBE2Q2 | Ubiquitin conjugating enzyme E2 Q2 | [
"Q8WVN8"
] | 15 | 75843307-75901078 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"DKFZp762C143"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [] | [] | [] | [] | null | null | null | 5 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 27: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 40: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,830 | 9 |
ENSG00000140368 | PSTPIP1 | Proline-serine-threonine phosphatase interacting protein 1 | [
"O43586"
] | 15 | 76993359-77037475 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA010116",
"HPA010600",
"HPA072744"
] | [
"CD2BP1",
"CD2BP1L",
"CD2BP1S",
"H-PIP",
"PAPAS",
"PSTPIP"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell adhesion",
"Endocytosis",
"Immunity",
"Inflammatory response",
"Innate immunity"
] | [] | [
"Disease variant"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 53 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Group enriched | Detected in many | 4 | Group enriched | Detected in some | 5 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | 7,831 | 7 |
ENSG00000140374 | ETFA | Electron transfer flavoprotein subunit alpha | [
"P13804"
] | 15 | 76188555-76311730 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018990",
"HPA018993",
"HPA018996",
"HPA024089"
] | [
"EMA",
"GA2",
"MADD"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Electron transport",
"Transport"
] | [] | [
"Disease variant",
"Glutaricaciduria"
] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Enhanced | null | 33 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 21: Non-specific - Metabolism | Cluster 58: Non-specific - Nuclear processes | Cluster 47: Platelets - Hemostasis | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,832 | 7 |
ENSG00000140379 | BCL2A1 | BCL2 related protein A1 | [
"Q16548"
] | 15 | 79960892-79971196 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"ACC-1",
"ACC-2",
"ACC1",
"ACC2",
"BCL2L5",
"BFL1",
"GRS",
"HBPA1"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | null | null | 14 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 12: Non-specific - Vasculature | Cluster 55: Lymphoma - Immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in many | 6 | Group enriched | Detected in many | 6 | Cancer enhanced | Detected in all | null | Cell type enriched | Detected in many | 4 | Group enriched | Detected in all | 5 | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 7,833 | 9 |
ENSG00000140382 | HMG20A | High mobility group 20A | [
"Q9NP66"
] | 15 | 77420412-77485607 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007685",
"HPA008126"
] | [
"FLJ10739",
"HMGX1",
"HMGXB1"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Supported | null | 109 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 58: Non-specific - Nuclear processes | Cluster 55: Myocytes - Oxidative muscle function | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 7,834 | 3 |
ENSG00000140386 | SCAPER | S-phase cyclin A associated protein in the ER | [
"Q9BY12"
] | 15 | 76347904-76905444 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046253",
"HPA048077"
] | [
"Zfp291",
"ZNF291"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant",
"Intellectual disability",
"Retinitis pigmentosa"
] | [
"Nucleoplasm",
"Nuclear speckles"
] | [
"Primary cilium",
"Primary cilium tip",
"Basal body",
"Cytosol"
] | [] | [] | Supported | Approved | null | 5 | null | No | Cluster 22: Eosinophils - Transcription | Cluster 31: Non-specific - Transcription | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 7,835 | 9 |
ENSG00000140391 | TSPAN3 | Tetraspanin 3 | [
"O60637"
] | 15 | 77041404-77083984 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA015996"
] | [
"TM4-A",
"TM4SF8",
"TSPAN-3"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Nucleoplasm",
"Golgi apparatus"
] | [] | [] | [] | Approved | Uncertain | null | 15 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Group enriched | Detected in all | 4 | 0 | 0 | 0 | [] | [] | [] | 7,836 | 8 |
ENSG00000140395 | SKIC8 | SKI8 subunit of superkiller complex | [
"Q9GZS3"
] | 15 | 78277835-78299703 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039932",
"HPA040065"
] | [
"REC14",
"SKI8",
"WDR61"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Wnt signaling pathway"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 116 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 55: Non-specific - Transcription | Cluster 58: Non-specific - Nuclear processes | Cluster 75: Non-specific - Chaperones and protein folding | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,837 | 1 |
ENSG00000140396 | NCOA2 | Nuclear receptor coactivator 2 | [
"Q15596"
] | 8 | 70109782-70403808 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA060243"
] | [
"bHLHe75",
"GRIP1",
"KAT13C",
"NCoA-2",
"TIF2"
] | [
"Cancer-related genes",
"Disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [] | [] | [] | Supported | null | null | 40 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 40: Non-specific - Unknown function | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 40: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 7,838 | 7 |
ENSG00000140398 | NEIL1 | Nei like DNA glycosylase 1 | [
"Q96FI4"
] | 15 | 75346955-75357115 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054084"
] | [
"FLJ22402",
"FPG1",
"hFPG1",
"NEI1"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"DNA-binding",
"Glycosidase",
"Hydrolase",
"Lyase",
"Multifunctional enzyme"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 178 | null | null | Cluster 24: Non-specific - Transcription | Cluster 15: Non-specific - Transcription | Cluster 71: Lymphoma - Inflammatory response | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,839 | 7 |
ENSG00000140400 | MAN2C1 | Mannosidase alpha class 2C member 1 | [
"Q9NTJ4"
] | 15 | 75355207-75368612 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040627",
"HPA067407"
] | [
"MANA",
"MANA1"
] | [
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Glycosidase",
"Hydrolase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 4 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 34: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 105: Non-specific - Mixed function | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,840 | 8 |
ENSG00000140403 | DNAJA4 | DnaJ heat shock protein family (Hsp40) member A4 | [
"Q8WW22"
] | 15 | 78264086-78282196 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004646",
"HPA041790"
] | [
"PRO1472"
] | [
"Predicted intracellular proteins"
] | [] | [
"Chaperone"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Nuclear membrane",
"Primary cilium",
"Centriolar satellite",
"Basal body"
] | [] | [] | Approved | Uncertain | null | 16 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 1: Neurons - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 7,841 | 1 |
ENSG00000140406 | TLNRD1 | Talin rod domain containing 1 | [
"Q9H1K6"
] | 15 | 81000923-81005788 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA071716"
] | [
"MESDC1",
"MGC99595"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytoplasmic bodies"
] | [] | [] | [] | Approved | null | null | 4 | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 5: Spleen - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma"
] | 7,842 | 3 |
ENSG00000140416 | TPM1 | Tropomyosin 1 | [
"P09493"
] | 15 | 63042632-63071915 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000261",
"HPA009066",
"CAB017698",
"HPA047089",
"HPA053624"
] | [
"C15orf13",
"CMH3"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Actin-binding",
"Muscle protein"
] | [
"Cancer-related genes",
"Cardiomyopathy",
"Disease variant"
] | [
"Actin filaments"
] | [
"Cytosol"
] | [] | [] | Approved | Supported | null | 35 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 15: Kidney cancer - Membrane components | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 41: Striated muscle - Muscle contraction | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 7,843 | 2 |
ENSG00000140443 | IGF1R | Insulin like growth factor 1 receptor | [
"P08069"
] | 15 | 98648539-98964530 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004822",
"CAB010268",
"HPA045563"
] | [
"CD221",
"IGFIR",
"IGFR",
"JTK13",
"MGC18216"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"RAS pathway related proteins"
] | [
"Host-virus interaction"
] | [
"Kinase",
"Receptor",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets"
] | [
"Nucleoli",
"Plasma membrane"
] | [
"Nucleoli rim",
"Primary cilium"
] | [] | [] | Approved | Approved | null | 128 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 42: Choroid plexus - Mitochondria | Cluster 58: Non-specific - Nuclear processes | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 8: Pancreas - Proteolysis | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 7,844 | 5 |
ENSG00000140451 | PIF1 | PIF1 5'-to-3' DNA helicase | [
"Q9H611"
] | 15 | 64815632-64825668 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB018701"
] | [
"C15orf20",
"FLJ22692"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA recombination",
"DNA repair"
] | [
"DNA-binding",
"Helicase",
"Hydrolase",
"Isomerase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | null | null | Yes | null | Cluster 1: Neurons - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 27: Non-specific - Cell proliferation | Cluster 34: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 5 | 2 | 4 | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 7,846 | 7 |
ENSG00000140459 | CYP11A1 | Cytochrome P450 family 11 subfamily A member 1 | [
"P05108"
] | 15 | 74337759-74367646 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA016436"
] | [
"CYP11A",
"P450SCC"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Cholesterol metabolism",
"Lipid biosynthesis",
"Lipid metabolism",
"Steroid biosynthesis",
"Steroid metabolism",
"Steroidogenesis",
"Sterol metabolism"
] | [
"Monooxygenase",
"Oxidoreductase"
] | [
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | 1 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 44: Non-specific - Mixed function | Cluster 34: Testis cancer - Unknown function | Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func. | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enriched | Detected in many | 25 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 48 | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,848 | 8 |
ENSG00000140463 | BBS4 | Bardet-Biedl syndrome 4 | [
"Q96RK4"
] | 15 | 72686179-72738475 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039418"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation",
"Protein transport",
"Sensory transduction",
"Transport",
"Vision"
] | [] | [
"Bardet-Biedl syndrome",
"Ciliopathy",
"Disease variant",
"Intellectual disability",
"Obesity"
] | [
"Cytosol",
"Flagellar centriole",
"Principal piece"
] | [
"Acrosome",
"Perinuclear theca",
"Annulus"
] | [] | [] | Approved | Approved | null | 36 | null | null | Cluster 24: Non-specific - Transcription | Cluster 44: Non-specific - Mixed function | Cluster 60: Prostate cancer - Unknown function | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 7,849 | 2 |
ENSG00000140464 | PML | PML nuclear body scaffold | [
"P29590"
] | 15 | 73994673-74047827 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008312",
"CAB010194",
"CAB016304"
] | [
"MYL",
"RNF71",
"TRIM19"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"Apoptosis",
"Biological rhythms",
"Host-virus interaction",
"Immunity",
"Innate immunity",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Transferase"
] | [
"Cancer-related genes",
"Proto-oncogene",
"Tumor suppressor"
] | [
"Nuclear bodies"
] | [] | [] | [] | Enhanced | Supported | null | 191 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 7,850 | 2 |
ENSG00000140465 | CYP1A1 | Cytochrome P450 family 1 subfamily A member 1 | [
"P04798"
] | 15 | 74719542-74725536 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB018654"
] | [
"CP11",
"CYP1",
"P1-450",
"P450-C",
"P450DX"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid metabolism",
"Steroid biosynthesis"
] | [
"Lyase",
"Monooxygenase",
"Oxidoreductase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 1 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 10 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,851 | 1 |
ENSG00000140470 | ADAMTS17 | ADAM metallopeptidase with thrombospondin type 1 motif 17 | [
"Q8TE56"
] | 15 | 99971437-100342005 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA062487"
] | [
"FLJ16363",
"FLJ32769"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Deafness",
"Dwarfism"
] | [
"Nucleoplasm"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Enzyme"
] | Approved | null | null | null | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Lung Squamous Cell Carcinoma"
] | 7,852 | 2 |
ENSG00000140471 | LINS1 | Lines homolog 1 | [
"Q8NG48"
] | 15 | 100559369-100603230 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038578",
"HPA038579"
] | [
"LINS",
"MRT27",
"WINS1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 9: Non-specific - Receptor signaling | Cluster 58: Non-specific - Nuclear processes | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 7,853 | 3 |
ENSG00000140474 | ULK3 | Unc-51 like kinase 3 | [
"Q6PHR2"
] | 15 | 74836118-74843346 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040474"
] | [
"DKFZP434C131",
"FLJ90566"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Autophagy"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Acrosome"
] | [] | [] | [] | Approved | Approved | null | 13 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 24: Neurons - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 84: Apical squamous epithelium - Cornification | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 7,854 | 4 |
ENSG00000140478 | GOLGA6D | Golgin A6 family member D | [
"P0CG33"
] | 15 | 75282835-75295807 | Evidence at protein level | Evidence at protein level | No human protein/transcript evidence | Evidence at protein level | [
"HPA044978",
"HPA050087",
"HPA072134"
] | [] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [
"Nucleoplasm",
"Centrosome"
] | [] | [] | Approved | Supported | null | null | null | null | null | null | Cluster 33: Sarcoma - Muscle contraction | Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase | Cluster 23: Testis - Spermatogenesis | Tissue enriched | Detected in single | 26 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,855 | 2 |
ENSG00000140481 | CCDC33 | Coiled-coil domain containing 33 | [
"Q8N5R6"
] | 15 | 74202705-74336472 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CT61",
"FLJ32855"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | 20 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 56: Ciliated tissues - Cilium organization | Group enriched | Detected in some | 6 | Cancer enhanced | Detected in single | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,857 | 5 |
ENSG00000140488 | CELF6 | CUGBP Elav-like family member 6 | [
"Q96J87"
] | 15 | 72284727-72320157 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA046985",
"HPA053526"
] | [
"BRUNOL6"
] | [
"Predicted intracellular proteins"
] | [
"mRNA processing"
] | [
"RNA-binding"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 1 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 64: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,858 | 1 |
ENSG00000140497 | SCAMP2 | Secretory carrier membrane protein 2 | [
"O15127"
] | 15 | 74843730-74873365 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014699",
"HPA019194"
] | [] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Golgi apparatus",
"Vesicles"
] | [
"Mid piece",
"Principal piece"
] | [] | [] | Supported | Approved | null | 69 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 8: Immune cells - Immune response | Cluster 58: Non-specific - Nuclear processes | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 17: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,859 | 4 |
ENSG00000140505 | CYP1A2 | Cytochrome P450 family 1 subfamily A member 2 | [
"P05177"
] | 15 | 74748845-74756607 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016531"
] | [
"CP12",
"P3-450"
] | [
"Cancer-related genes",
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism",
"Steroid metabolism",
"Sterol metabolism"
] | [
"Lyase",
"Monooxygenase",
"Oxidoreductase"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Enhanced | null | 2 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 48: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 236 | Low cancer specificity | Detected in single | null | Group enriched | Detected in some | 4 | Cell type enriched | Detected in some | 7 | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 7,860 | 7 |
ENSG00000140506 | LMAN1L | Lectin, mannose binding 1 like | [
"Q9HAT1"
] | 15 | 74812716-74825757 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [] | [
"ERGIC-53L",
"ERGL"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 25: Non-specific - Transcription | Cluster 60: Prostate cancer - Unknown function | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 35: Non-specific - Mixed function | Group enriched | Detected in some | 6 | Cancer enriched | Detected in single | 6 | Cancer enriched | Detected in single | 36 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,861 | 4 |
ENSG00000140511 | HAPLN3 | Hyaluronan and proteoglycan link protein 3 | [
"Q96S86"
] | 15 | 88877294-88895597 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA039237"
] | [
"EXLD1",
"HsT19883"
] | [
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | Approved | Approved | null | 4 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 47: Endothelial cells - Vasculature | Cluster 64: Connective tissue cells - ECM organization | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enriched | Detected in many | 5 | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 7,862 | 6 |
ENSG00000140519 | RHCG | Rh family C glycoprotein | [
"Q9UBD6"
] | 15 | 89471398-89496589 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041874",
"HPA043317"
] | [
"C15orf6",
"PDRC2",
"RHGK",
"SLC42A3"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ammonia transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 17 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 81: Squamous epithelium - Keratinization | Group enriched | Detected in many | 4 | Group enriched | Detected in some | 5 | Cancer enriched | Detected in many | 5 | Group enriched | Detected in many | 9 | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Chromophobe"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,863 | 9 |
ENSG00000140522 | RLBP1 | Retinaldehyde binding protein 1 | [
"P12271"
] | 15 | 89209869-89221614 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042051",
"HPA044083"
] | [
"CRALBP"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Sensory transduction",
"Transport",
"Vision"
] | [] | [
"Disease variant"
] | [
"Cytosol"
] | [
"Nucleoplasm",
"Centrosome"
] | [] | [] | Supported | Enhanced | Approved | 1 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 23: Choroid plexus - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in some | 16 | Group enriched | Detected in some | 13 | Group enriched | Detected in some | 28 | Group enriched | Detected in some | 90 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,865 | 1 |
ENSG00000140525 | FANCI | FA complementation group I | [
"Q9NVI1"
] | 15 | 89243945-89317261 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039972",
"HPA040379"
] | [
"FLJ10719",
"KIAA1794"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell cycle",
"DNA damage",
"DNA repair"
] | [
"DNA-binding"
] | [
"Disease variant",
"Fanconi anemia"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 26 | null | null | Cluster 32: Basophils - Transcription | Cluster 37: Neurons - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 4 | 2 | 3 | [
"Glioblastoma Multiforme"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 7,866 | 3 |
ENSG00000140526 | ABHD2 | Abhydrolase domain containing 2, acylglycerol lipase | [
"P08910"
] | 15 | 89087459-89202355 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA005999"
] | [
"LABH2"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Lipid degradation",
"Lipid metabolism"
] | [
"Hydrolase",
"Serine esterase"
] | [] | [
"Cytosol",
"Flagellar centriole"
] | [
"Nucleoplasm",
"Connecting piece"
] | [] | [] | Approved | Approved | null | null | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 23: Choroid plexus - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 7,867 | 2 |
ENSG00000140534 | TICRR | TOPBP1 interacting checkpoint and replication regulator | [
"Q7Z2Z1"
] | 15 | 89575469-89631056 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046746",
"HPA049454"
] | [
"C15orf42",
"FLJ41618",
"MGC45866",
"SLD3",
"Treslin"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"DNA damage",
"DNA repair"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 9 | null | Yes | null | Cluster 12: Non-specific - Vasculature | Cluster 58: Non-specific - Nuclear processes | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 7,869 | 1 |
ENSG00000140538 | NTRK3 | Neurotrophic receptor tyrosine kinase 3 | [
"Q16288"
] | 15 | 87859751-88256791 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009233",
"HPA027484",
"HPA048065"
] | [
"TRKC"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein",
"Kinase",
"Receptor",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Nucleoli",
"Nucleoli rim"
] | [
"Nuclear membrane"
] | [] | [] | Supported | Approved | null | 59 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 74: Non-specific - Signal transduction | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Breast Invasive Carcinoma"
] | [] | [
"Breast Invasive Carcinoma"
] | 7,870 | 8 |
ENSG00000140543 | DET1 | DET1 partner of COP1 E3 ubiquitin ligase | [
"Q7L5Y6"
] | 15 | 88494440-88546681 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048873"
] | [
"FLJ10103"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [] | [
"Microtubules"
] | [
"Nucleoplasm",
"Cytokinetic bridge"
] | [] | [] | Approved | Uncertain | null | 38 | Yes | No | Cluster 29: Non-specific - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 105: Non-specific - Mixed function | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,871 | 5 |
ENSG00000140545 | MFGE8 | Milk fat globule EGF and factor V/VIII domain containing | [
"Q08431"
] | 15 | 88898683-88913468 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002753",
"HPA002807"
] | [
"BA46",
"EDIL1",
"hP47",
"HsT19888",
"MFG-E8",
"OAcGD3S",
"SED1",
"SPAG10"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Angiogenesis",
"Cell adhesion",
"Fertilization"
] | [] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [] | [
"Secreted to blood"
] | [
"Cell adhesion"
] | Approved | Enhanced | null | 1 | null | null | Cluster 16: Non-specific - Cell proliferation | Cluster 30: White matter - Myelination | Cluster 64: Connective tissue cells - ECM organization | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Stomach Adenocarcinoma"
] | 7,872 | 2 |
ENSG00000140557 | ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 | [
"Q92186"
] | 15 | 92393881-92468728 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA054518",
"HPA057819"
] | [
"HsT19690",
"SIAT8B",
"ST8SIA-II",
"STX"
] | [
"Predicted secreted proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Secreted - unknown location"
] | [
"Enzyme"
] | Supported | Approved | null | 7 | null | null | null | Cluster 49: Hindbrain - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | Cluster 35: Non-specific - Mixed function | Tissue enhanced | Detected in some | null | Group enriched | Detected in some | 5 | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,875 | 4 |
ENSG00000140563 | MCTP2 | Multiple C2 and transmembrane domain containing 2 | [
"Q6DN12"
] | 15 | 94231538-94483952 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051176",
"HPA070541"
] | [
"FLJ11175",
"FLJ33303"
] | [
"Disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Developmental protein"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Enhanced | Uncertain | null | null | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 7,876 | 6 |
ENSG00000140575 | IQGAP1 | IQ motif containing GTPase activating protein 1 | [
"P46940"
] | 15 | 90388242-90502239 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013302",
"HPA014055"
] | [
"HUMORFA01",
"KIAA0051",
"p195",
"SAR1"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction"
] | [
"Calmodulin-binding"
] | [] | [
"Plasma membrane",
"Cell Junctions"
] | [] | [] | [] | Supported | Enhanced | null | 116 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 11: White matter - Signal transduction | Cluster 58: Non-specific - Nuclear processes | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 13: Lung - Secretion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,878 | 8 |
ENSG00000140577 | CRTC3 | CREB regulated transcription coactivator 3 | [
"Q6UUV7"
] | 15 | 90529923-90645345 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043735",
"HPA063691"
] | [
"FLJ21868"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | Approved | null | 24 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 13: Oligodendrocytes - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Immune cell enhanced | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,879 | 4 |
ENSG00000140598 | EFL1 | Elongation factor like GTPase 1 | [
"Q7Z2Z2"
] | 15 | 82130206-82262773 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039654",
"HPA047110",
"HPA052345"
] | [
"EFTUD1",
"FAM42A",
"FLJ13119",
"HsT19294",
"RIA1"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis",
"Ribosome biogenesis"
] | [
"Elongation factor",
"Hydrolase"
] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 5 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 58: Non-specific - Nuclear processes | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,880 | 7 |
ENSG00000140600 | SH3GL3 | SH3 domain containing GRB2 like 3, endophilin A3 | [
"Q99963"
] | 15 | 83447228-83618743 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039381",
"HPA077877"
] | [
"CNSA3",
"EEN-B2",
"HsT19371",
"SH3D2C",
"SH3P13"
] | [
"Predicted intracellular proteins"
] | [
"Endocytosis"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Enhanced | null | 25 | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 12: Bone cancer - Neuronal signaling | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,881 | 5 |
ENSG00000140623 | SEPTIN12 | Septin 12 | [
"Q8IYM1"
] | 16 | 4777606-4788398 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041128"
] | [
"FLJ25410",
"SEPT12"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Differentiation",
"Spermatogenesis"
] | [] | [
"Disease variant"
] | [
"Microtubules"
] | [
"Annulus"
] | [] | [] | Supported | null | null | 13 | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 23: Testis - Spermatogenesis | Tissue enriched | Detected in some | 37 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in some | 16 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,883 | 9 |
ENSG00000140650 | PMM2 | Phosphomannomutase 2 | [
"O15305"
] | 16 | 8788823-8862534 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA063649"
] | [
"CDG1",
"CDG1a",
"CDGS",
"PMI",
"PMI1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Isomerase"
] | [
"Congenital disorder of glycosylation",
"Disease variant"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Microtubules",
"Primary cilium",
"Primary cilium tip"
] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 36: Choroid plexus - Mixed function | Cluster 54: Non-specific - Transcription | Cluster 8: Non-specific - Secretory pathway | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enriched | Detected in all | 8 | 4 | 2 | 3 | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 7,885 | 2 |
ENSG00000140675 | SLC5A2 | Solute carrier family 5 member 2 | [
"P31639"
] | 16 | 31483002-31490860 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041603"
] | [
"SGLT2"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Sodium transport",
"Sugar transport",
"Symport",
"Transport"
] | [] | [
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | 2 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 72: Kidney - Transmembrane transport | Tissue enriched | Detected in some | 18 | Not detected | Not detected | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 7,886 | 4 |
ENSG00000140678 | ITGAX | Integrin subunit alpha X | [
"P20702"
] | 16 | 31355134-31382999 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004458",
"HPA004723",
"CAB072871",
"CAB080214"
] | [
"CD11C"
] | [
"CD markers",
"FDA approved drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [
"Integrin",
"Receptor"
] | [
"FDA approved drug targets"
] | [
"Vesicles",
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 2 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 12: Non-specific - Vasculature | Cluster 49: HMC-1 - Innate immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 7,887 | 1 |
ENSG00000140682 | TGFB1I1 | Transforming growth factor beta 1 induced transcript 1 | [
"O43294"
] | 16 | 31471585-31477960 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB020844",
"HPA072360"
] | [
"ARA55",
"Hic-5",
"TSC-5"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Wnt signaling pathway"
] | [
"Activator"
] | [] | [
"Focal adhesion sites"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 17 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 47: Endothelial cells - Vasculature | Cluster 72: Neuronal - Signal transduction | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 6 | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 7,888 | 7 |
ENSG00000140688 | RUSF1 | RUS family member 1 | [
"Q96GQ5"
] | 16 | 31489471-31509309 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA024406"
] | [
"C16orf58",
"FLJ13868"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoli",
"Golgi apparatus",
"Vesicles"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 77 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 14: Neurons - Synaptic function | Cluster 54: Non-specific - Transcription | Cluster 8: Non-specific - Secretory pathway | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,889 | 5 |
ENSG00000140691 | ARMC5 | Armadillo repeat containing 5 | [
"Q96C12"
] | 16 | 31458080-31467166 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041524",
"HPA063706"
] | [
"FLJ13063"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [
"Cushing syndrome",
"Disease variant"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Focal adhesion sites"
] | [] | [] | Approved | Approved | null | 13 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 49: Hindbrain - Mixed function | Cluster 35: RS4;11 - Unknown function | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 7,890 | 1 |
ENSG00000140694 | PARN | Poly(A)-specific ribonuclease | [
"O95453"
] | 16 | 14435700-14632728 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006314",
"CAB011673",
"HPA012010"
] | [
"DAN"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Nonsense-mediated mRNA decay"
] | [
"Exonuclease",
"Hydrolase",
"Nuclease",
"RNA-binding"
] | [
"Disease variant",
"Dyskeratosis congenita"
] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Supported | null | 24 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 46: Lymphoma - Humoral immune response | Cluster 102: Non-specific - Mixed function | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Stomach Adenocarcinoma"
] | [
"Stomach Adenocarcinoma"
] | 7,891 | 5 |
ENSG00000140718 | FTO | FTO alpha-ketoglutarate dependent dioxygenase | [
"Q9C0B1"
] | 16 | 53701692-54158512 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017123",
"HPA041086",
"HPA068695"
] | [
"ALKBH9",
"KIAA1752",
"MGC5149"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Dioxygenase",
"Oxidoreductase",
"Transferase"
] | [
"Disease variant",
"Obesity"
] | [
"Cytosol"
] | [
"Vesicles"
] | [] | [] | Supported | Enhanced | null | 9 | No | No | Cluster 16: Non-specific - Cell proliferation | Cluster 31: Non-specific - Transcription | Cluster 68: Non-specific - Cell cycle regulation | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 36: Brain & Liver - Signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,892 | 1 |
ENSG00000140740 | UQCRC2 | Ubiquinol-cytochrome c reductase core protein 2 | [
"P22695"
] | 16 | 21953288-21983660 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007998",
"HPA019146"
] | [
"QCR2",
"UQCR2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Electron transport",
"Respiratory chain",
"Transport"
] | [] | [
"Disease variant",
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Enhanced | null | 51 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 23: Choroid plexus - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 7,893 | 6 |
ENSG00000140743 | CDR2 | Cerebellar degeneration related protein 2 | [
"Q01850"
] | 16 | 22345936-22437165 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018151",
"HPA023870"
] | [
"CDR62",
"Yo"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 95 | null | null | Cluster 6: T-cells - T-cell receptor | Cluster 23: Choroid plexus - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 7,894 | 8 |
ENSG00000140749 | IGSF6 | Immunoglobulin superfamily member 6 | [
"O95976"
] | 16 | 21639550-21652608 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA041023",
"HPA041072"
] | [
"DORA"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 66: Lymphoid tissue - Immune response | Tissue enriched | Detected in many | 4 | Not detected | Not detected | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 7,895 | 3 |
ENSG00000140750 | ARHGAP17 | Rho GTPase activating protein 17 | [
"Q68EM7"
] | 16 | 24919389-25015666 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041703",
"HPA075891"
] | [
"FLJ10308",
"FLJ13219",
"NADRIN",
"RICH1",
"WBP15"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 30 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 30: White matter - Myelination | Cluster 55: Lymphoma - Immune response | Cluster 102: Non-specific - Mixed function | Cluster 5: Spleen - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Breast Invasive Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,896 | 7 |
ENSG00000140795 | MYLK3 | Myosin light chain kinase 3 | [
"Q32MK0"
] | 16 | 46702282-46790407 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA073447"
] | [
"caMLCK",
"MLCK"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 1 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 41: Striated muscle - Muscle contraction | Group enriched | Detected in some | 13 | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,897 | 2 |
ENSG00000140798 | ABCC12 | ATP binding cassette subfamily C member 12 | [] | 16 | 48080882-48156018 | Evidence at transcript level | Evidence at transcript level | null | null | [
"HPA043100"
] | [
"MRP9"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 1 | null | null | null | Cluster 34: Non-specific - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling | Cluster 61: Non-specific - Transcription | Group enriched | Detected in some | 4 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,898 | 7 |
ENSG00000140807 | NKD1 | NKD inhibitor of WNT signaling pathway 1 | [
"Q969G9"
] | 16 | 50548396-50649249 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041352",
"HPA049413"
] | [] | [
"Predicted intracellular proteins"
] | [
"Wnt signaling pathway"
] | [] | [] | [
"Nucleoli fibrillar center"
] | [] | [] | [] | Approved | Uncertain | null | 11 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 32: Non-specific - Cell proliferation | Cluster 57: Podocytes - Glomerular filtration | Cluster 74: Non-specific - Signal transduction | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 7,899 | 5 |
ENSG00000140829 | DHX38 | DEAH-box helicase 38 | [
"Q92620"
] | 16 | 72093613-72112912 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041347",
"HPA041604"
] | [
"DDX38",
"hPrp16",
"KIAA0224",
"PRP16",
"PRPF16"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Helicase",
"Hydrolase"
] | [
"Disease variant",
"Retinitis pigmentosa"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 35 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 6: Non-specific - Immune response | Cluster 68: Non-specific - Cell cycle regulation | Cluster 17: Non-specific - RNA processing | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | 7,900 | 3 |
ENSG00000140830 | TXNL4B | Thioredoxin like 4B | [
"Q9NX01"
] | 16 | 72044289-72094431 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065865"
] | [
"Dim2",
"DLP",
"FLJ20511"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 20 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 55: Non-specific - Transcription | Cluster 68: Non-specific - Cell cycle regulation | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 6 | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 7,901 | 2 |
ENSG00000140832 | MARVELD3 | MARVEL domain containing 3 | [
"Q96A59"
] | 16 | 71626161-71642114 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA043514",
"HPA045471"
] | [
"MRVLDC3"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Vesicles"
] | [
"Intermediate filaments"
] | [] | [] | Approved | null | null | null | No | null | Cluster 35: Neutrophils - Protein binding | Cluster 48: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,902 | 8 |
ENSG00000140835 | CHST4 | Carbohydrate sulfotransferase 4 | [
"Q8NCG5"
] | 16 | 71525233-71538748 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021955"
] | [
"HEC-GLCNAC-6-ST",
"LSST"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism",
"Inflammatory response"
] | [
"Transferase"
] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | Cluster 44: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 13: Lung - Secretion | Tissue enriched | Detected in some | 6 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 7 | Cell type enriched | Detected in some | 9 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,903 | 9 |
ENSG00000140836 | ZFHX3 | Zinc finger homeobox 3 | [
"Q15911"
] | 16 | 72782885-73891871 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA059353"
] | [
"ATBF1",
"C16orf47",
"FLJ26184",
"ZNF927"
] | [
"Cancer-related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Myogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [
"Atrial fibrillation",
"Cancer-related genes",
"Neurodegeneration",
"Spinocerebellar ataxia"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 4 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 50: Lymphoma - Unknown function | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in all | null | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,904 | 9 |
ENSG00000140839 | CLEC18B | C-type lectin domain family 18 member B | [
"Q6UXF7"
] | 16 | 74408631-74421478 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA048976"
] | [
"MRCL2"
] | [
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | null | Uncertain | null | null | null | null | null | Cluster 54: Immune cells - T cell receptor | Cluster 11: Neuronal - Sensory perception | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 72: Kidney - Transmembrane transport | Tissue enriched | Detected in some | 7 | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 4 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 7,905 | 2 |
ENSG00000140848 | CPNE2 | Copine 2 | [
"Q96FN4"
] | 16 | 57092583-57148369 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041132"
] | [
"CPN2"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Mitochondria",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 26 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 6: Leukemia - Signal transduction | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 7,906 | 8 |
ENSG00000140853 | NLRC5 | NLR family CARD domain containing 5 | [
"Q86WI3"
] | 16 | 56989485-57083531 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA060405",
"HPA074724"
] | [
"CLR16.1",
"FLJ21709",
"NOD27"
] | [
"Predicted intracellular proteins"
] | [
"Immunity",
"Innate immunity"
] | [] | [] | [
"Cytosol"
] | [
"Centrosome"
] | [] | [] | Supported | null | null | 2 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 43: Hindbrain - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 7,907 | 7 |
ENSG00000140854 | KATNB1 | Katanin regulatory subunit B1 | [
"Q9BVA0"
] | 16 | 57735739-57757244 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041165",
"HPA041839"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [
"Disease variant",
"Lissencephaly"
] | [
"Cytosol"
] | [
"Plasma membrane",
"Microtubules"
] | [] | [] | Supported | Enhanced | null | 25 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 68: Non-specific - Cell cycle regulation | Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase | Cluster 10: Brain - Synaptic signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 7,908 | 7 |
ENSG00000140859 | KIFC3 | Kinesin family member C3 | [
"Q9BVG8"
] | 16 | 57758217-57863053 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA021240"
] | [] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [] | [
"Motor protein"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Uncertain | null | 75 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 9: Non-specific - Receptor signaling | Cluster 72: Neuronal - Signal transduction | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 7,909 | 1 |
ENSG00000140873 | ADAMTS18 | ADAM metallopeptidase with thrombospondin type 1 motif 18 | [
"Q8TE60"
] | 16 | 77247813-77435034 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044326"
] | [
"ADAMTS21"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Midbody",
"Mitotic spindle"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Enzyme"
] | Approved | Uncertain | null | null | Yes | null | null | Cluster 25: Non-specific - Transcription | Cluster 70: DU4475 - Unknown function | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 43: Placenta - Pregnancy hormone signaling | Group enriched | Detected in some | 5 | Group enriched | Detected in some | 6 | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,910 | 4 |
ENSG00000140876 | NUDT7 | Nudix hydrolase 7 | [
"P0C024"
] | 16 | 77722492-77742260 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042042"
] | [] | [
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"RNA-binding"
] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Supported | null | null | null | null | Cluster 33: Non-specific - ATP binding | Cluster 23: Choroid plexus - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 97: Non-specific - Cellular respiration | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,911 | 5 |
ENSG00000140905 | GCSH | Glycine cleavage system protein H | [
"P23434"
] | 16 | 81081945-81096395 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041368",
"HPA057079"
] | [] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant",
"Neurodegeneration"
] | [
"Vesicles"
] | [] | [] | [] | Approved | Supported | null | 12 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 19: Astrocytes - Mixed function | Cluster 68: Non-specific - Cell cycle regulation | Cluster 30: Epididymal principal cells - Sperm storage microenvironment | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 7,912 | 6 |
ENSG00000140931 | CMTM3 | CKLF like MARVEL transmembrane domain containing 3 | [
"Q96MX0"
] | 16 | 66603874-66613892 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA013870",
"HPA072695"
] | [
"BNAS2",
"CKLFSF3",
"FLJ31762"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Chemotaxis"
] | [
"Cytokine"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 19 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 39: Astrocytes - Mixed function | Cluster 68: Non-specific - Cell cycle regulation | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 43: Placenta - Pregnancy hormone signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Lung Adenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 7,913 | 4 |
ENSG00000140932 | CMTM2 | CKLF like MARVEL transmembrane domain containing 2 | [
"Q8TAZ6"
] | 16 | 66579448-66588275 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CKLFSF2",
"FLJ25732",
"MGC39436"
] | [
"Predicted membrane proteins"
] | [
"Chemotaxis"
] | [
"Cytokine"
] | [] | [] | [] | [] | [] | null | null | null | 10 | null | null | Cluster 4: Neutrophils - Degranulation | Cluster 34: Non-specific - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 23: Testis - Spermatogenesis | Tissue enriched | Detected in some | 421 | Low cancer specificity | Detected in single | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 5 | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 7,914 | 2 |
ENSG00000140939 | NOL3 | Nucleolar protein 3 | [
"O60936"
] | 16 | 67170154-67175737 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009208"
] | [
"ARC",
"CARD2",
"MYP",
"NOP30"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"mRNA processing",
"mRNA splicing"
] | [] | [
"Disease variant"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 9 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 45: Non-specific - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 4 | 2 | 3 | [] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,916 | 2 |
ENSG00000140943 | MBTPS1 | Membrane bound transcription factor peptidase, site 1 | [
"Q14703"
] | 16 | 84053761-84116942 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA056109"
] | [
"KIAA0091",
"PCSK8",
"S1P",
"SKI-1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cholesterol metabolism",
"Lipid metabolism",
"Steroid metabolism",
"Sterol metabolism"
] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Disease variant",
"Dwarfism"
] | [] | [] | [] | [] | null | Supported | null | 26 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 68: Non-specific - Cell cycle regulation | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,918 | 9 |
ENSG00000140945 | CDH13 | Cadherin 13 | [
"P55290"
] | 16 | 82626965-83800640 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001380",
"CAB025863"
] | [
"CDHH"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Plasma membrane"
] | [] | [
"Intracellular and membrane"
] | [
"Cell adhesion"
] | Supported | Enhanced | null | 3 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 14: Neurons - Synaptic function | Cluster 64: Connective tissue cells - ECM organization | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 7,919 | 7 |
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