interpro_id string | interpro_numeric_id int64 | name string | short_name string | entry_type string | protein_count int64 | is_llm bool | is_llm_reviewed bool | abstract string | go_ids list | go_terms list | go_categories list | go_count int64 | member_databases list | member_accessions list | member_names list | member_protein_counts list | member_count int64 | external_databases list | external_accessions list | external_xrefs list | external_xref_count int64 | pdb_ids list | structure_count int64 | publication_ids list | pubmed_ids list | publication_titles list | publication_years list | publication_count int64 | parent_ids list | child_ids list | parent_count int64 | child_count int64 | tree_depth float64 | taxonomy_names list | taxonomy_protein_counts list | taxonomy_count int64 | key_species_names list | key_species_protein_counts list | key_species_count int64 | in_entry_list bool | entry_list_type string | entry_list_name string | names_dat_name string | short_names_dat_name string | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IPR021255 | 21,255 | Putative auto-transporter adhesin, head GIN domain | DUF2807 | Domain | 12,915 | false | false | Proteins containing this domain show structural similarity to other pectin lyase families. Although these proteins align with acetyl-transferases, there is no conservation of catalytic residues found. It is likely that the function is one of cell-adhesion. In , it is interesting to note that the polypeptide contains se... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10988"
] | [
"DUF2807"
] | [
12915
] | 1 | [] | [] | [] | 0 | [
"3jx8",
"3ljy",
"3lyc",
"3pet",
"4opw",
"4ygu",
"7muc",
"7mud",
"7muq",
"7mus",
"7muv",
"7muw",
"7muy",
"9ngu"
] | 14 | [
"PUB00029784",
"PUB00051306"
] | [
"14765110",
"18688279"
] | [
"The Yersinia adhesin YadA collagen-binding domain structure is a novel left-handed parallel beta-roll.",
"Structure of the head of the Bartonella adhesin BadA."
] | [
2004,
2008
] | 2 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
27,
12113,
617,
4,
154
] | 5 | [] | [] | 0 | true | Domain | Putative auto-transporter adhesin, head GIN domain | Putative auto-transporter adhesin, head GIN domain | DUF2807 | 8 |
IPR021256 | 21,256 | Protein of unknown function DUF2808 | DUF2808 | Family | 962 | false | false | This family of proteins with unknown function are mostly from Cyanobacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10989"
] | [
"DUF2808"
] | [
962
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillati",
"Halobacteriales"
] | [
959,
3
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2808 | Protein of unknown function DUF2808 | DUF2808 | 9 |
IPR021257 | 21,257 | Protein of unknown function DUF2809 | DUF2809 | Family | 3,961 | false | false | Some members in this family of proteins are annotated as yjgA however currently no function for the protein is known. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10990"
] | [
"DUF2809"
] | [
3961
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"ecological metagenomes"
] | [
3956,
5
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2809 | Protein of unknown function DUF2809 | DUF2809 | 3 |
IPR021258 | 21,258 | Epiplasmin protein | Epiplasmin | Family | 300 | false | false | This entry represents a group of epiplasmins, which are multigene family in Paramecium. They make up a scale structure called the epiplasm under the cell [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10992"
] | [
"Epiplasmin"
] | [
300
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00101292"
] | [
"19493334"
] | [
"Cross-study analysis of genomic data defines the ciliate multigenic epiplasmin family: strategies for functional analysis in Paramecium tetraurelia."
] | [
2009
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
300
] | 1 | [] | [] | 0 | true | Family | Epiplasmin protein | Epiplasmin protein | Epiplasmin | 7 |
IPR021259 | 21,259 | Protein of unknown function DUF2817 | DUF2817 | Family | 1,755 | false | false | This family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10994"
] | [
"DUF2817"
] | [
1755
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
1475,
266,
14
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2817 | Protein of unknown function DUF2817 | DUF2817 | 4 |
IPR021260 | 21,260 | Lipid II flippase Amj | Amj | Family | 1,332 | false | false | This entry includes lipid II flippase Amj, which is required for bacterial cell wall synthesis. It transports lipid-linked peptidoglycan precursors from the inner to the outer surface of the cytoplasmic membrane [ ]. | [] | [] | [] | 0 | [
"HAMAP",
"PFAM"
] | [
"MF_02077",
"PF10997"
] | [
"Amj_flippase",
"Amj"
] | [
1170,
1332
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00083236"
] | [
"25918422"
] | [
"MurJ and a novel lipid II flippase are required for cell wall biogenesis in Bacillus subtilis."
] | [
2015
] | 1 | [] | [] | 0 | 0 | null | [
"Aspergillus subgen. Circumdati",
"Bacteria",
"ecological metagenomes"
] | [
2,
1319,
11
] | 3 | [] | [] | 0 | true | Family | Lipid II flippase Amj | Lipid II flippase Amj | Amj | 7 |
IPR021261 | 21,261 | Glycerophosphocholine acyltransferase 1 | GPCAT | Family | 3,183 | false | false | Proteins in this family include glycerophosphocholine acyltransferase 1 (GPCAT). GPCAT homologues have been identified in most eukaryotes except chordates, but are not found in prokaryotes. GPCAT can acylate glycero-3-phosphocholine (GPC) with acyl groups from acyl-CoA. Thus it contributes to the maintenance of phospha... | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF10998",
"PTHR31201"
] | [
"DUF2838",
""
] | [
3042,
3131
] | 2 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC"... | [
"2.3.1.-",
"PWY-3602",
"PWY-361",
"PWY-4801",
"PWY-4922",
"PWY-5048",
"PWY-5139",
"PWY-5268",
"PWY-5284",
"PWY-5292",
"PWY-5307",
"PWY-5313",
"PWY-5317",
"PWY-5318",
"PWY-5353",
"PWY-5400",
"PWY-5473",
"PWY-5475",
"PWY-5477",
"PWY-5660",
"PWY-5679",
"PWY-5710",
"PWY-5794"... | [
"EC:2.3.1.-",
"METACYC:PWY-3602",
"METACYC:PWY-361",
"METACYC:PWY-4801",
"METACYC:PWY-4922",
"METACYC:PWY-5048",
"METACYC:PWY-5139",
"METACYC:PWY-5268",
"METACYC:PWY-5284",
"METACYC:PWY-5292",
"METACYC:PWY-5307",
"METACYC:PWY-5313",
"METACYC:PWY-5317",
"METACYC:PWY-5318",
"METACYC:PWY-53... | 219 | [] | 0 | [
"PUB00093705"
] | [
"27758859"
] | [
"Cloning of Glycerophosphocholine Acyltransferase (GPCAT) from Fungi and Plants: A NOVEL ENZYME IN PHOSPHATIDYLCHOLINE SYNTHESIS."
] | [
2016
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Klosneuvirinae",
"viral metagenome"
] | [
3178,
2,
3
] | 3 | [
"Arabidopsis thaliana",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea mays"
] | [
3,
1,
3,
1,
1,
12
] | 6 | true | Family | Glycerophosphocholine acyltransferase 1 | Glycerophosphocholine acyltransferase 1 | GPCAT | 2 |
IPR021262 | 21,262 | Protein of unknown function DUF2839 | DUF2839 | Family | 431 | false | false | This bacterial family of unknown function appear to be restricted to Cyanobacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10999"
] | [
"DUF2839"
] | [
431
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Cyanobacteriota",
"Eukaryota"
] | [
390,
41
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2839 | Protein of unknown function DUF2839 | DUF2839 | 9 |
IPR021263 | 21,263 | Protein of unknown function DUF2840 | DUF2840 | Family | 1,901 | false | false | This bacterial family of proteins have no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11000"
] | [
"DUF2840"
] | [
1901
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"metagenomes"
] | [
1874,
6,
21
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2840 | Protein of unknown function DUF2840 | DUF2840 | 8 |
IPR021264 | 21,264 | Subtelomeric hrmA-associated cluster protein AFUB_079030/YDR124W-like | AFUB_079030/YDR124W-like | Family | 1,925 | false | false | This family represents Subtelomeric hrmA-associated cluster protein AFUB_079030 from Aspergillus fumigatus and similar fungal proteins. AFUB_079030 is part of the subtelomeric hrmA-associated cluster (HAC) containing genes that alter the hyphal surface (such as reduced total chitin or increased beta-glucan exposure) an... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR36102"
] | [
""
] | [
1925
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00101836",
"PUB00153731"
] | [
"31945465",
"31548684"
] | [
"Predicting subcellular localization of proteins using protein-protein interaction data.",
"Fungal biofilm morphology impacts hypoxia fitness and disease progression."
] | [
2020,
2019
] | 2 | [] | [] | 0 | 0 | null | [
"Dikarya"
] | [
1925
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)"
] | [
1,
1
] | 2 | true | Family | Subtelomeric hrmA-associated cluster protein AFUB_079030/YDR124W-like | Subtelomeric hrmA-associated cluster protein AFUB_079030/YDR124W-like | AFUB_079030/YDR124W-like | 9 |
IPR021265 | 21,265 | Protein of unknown function DUF2842 | DUF2842 | Family | 2,351 | false | false | This bacterial family of proteins have no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11003"
] | [
"DUF2842"
] | [
2351
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Alphaproteobacteria",
"Puccinia triticina (isolate 1-1 / race 1 (BBBD))",
"ecological metagenomes"
] | [
2335,
1,
15
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2842 | Protein of unknown function DUF2842 | DUF2842 | 1 |
IPR021266 | 21,266 | Kdo hydroxylase | Kdo_hydroxlase | Family | 991 | false | false | This is a family of 3-deoxy-D-manno-oct-2-ulosonic acid 3-hydroxylases, which catalyse the conversion of 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) to D-glycero-D-talo-oct-2-ulosonic acid (Ko). It contains a potential iron-binding motif, HXDX(n)H (n>40). Hydroxylation activity is iron-dependent [ , ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11004"
] | [
"Kdo_hydroxy"
] | [
991
] | 1 | [] | [] | [] | 0 | [
"5y9i",
"5y9x",
"5y9y",
"5yka",
"5yvz",
"5yw0",
"6a2e"
] | 7 | [
"PUB00057446",
"PUB00162467"
] | [
"21178073",
"30092253"
] | [
"Dioxygenases in Burkholderia ambifaria and Yersinia pestis that hydroxylate the outer Kdo unit of lipopolysaccharide.",
"Biochemical and Structural Insights into an Fe(II)/α-Ketoglutarate/O<sub>2</sub>-Dependent Dioxygenase, Kdo 3-Hydroxylase (KdoO)."
] | [
2011,
2018
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Beauveria bassiana D1-5",
"ecological metagenomes"
] | [
982,
1,
8
] | 3 | [] | [] | 0 | true | Family | Kdo hydroxylase | Kdo hydroxylase | Kdo_hydroxlase | 9 |
IPR021267 | 21,267 | Protein of unknown function DUF2844 | DUF2844 | Family | 930 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11005"
] | [
"DUF2844"
] | [
930
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Lentinus tigrinus ALCF2SS1-6",
"mine drainage metagenome"
] | [
918,
1,
11
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2844 | Protein of unknown function DUF2844 | DUF2844 | 8 |
IPR021268 | 21,268 | Protein of unknown function DUF2845 | DUF2845 | Family | 1,567 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11006"
] | [
"DUF2845"
] | [
1567
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"unclassified sequences"
] | [
1555,
12
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2845 | Protein of unknown function DUF2845 | DUF2845 | 3 |
IPR021269 | 21,269 | Protein of unknown function DUF2848 | DUF2848 | Family | 1,895 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11010"
] | [
"DUF2848"
] | [
1895
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"unclassified sequences"
] | [
10,
1864,
21
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2848 | Protein of unknown function DUF2848 | DUF2848 | 2 |
IPR021270 | 21,270 | Protein of unknown function DUF2849 | DUF2849 | Family | 2,479 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11011"
] | [
"DUF2849"
] | [
2479
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
2457,
3,
19
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2849 | Protein of unknown function DUF2849 | DUF2849 | 1 |
IPR021271 | 21,271 | Protein of unknown function DUF2850 | DUF2850 | Family | 501 | false | false | This family of proteins with unknown function appear to be restricted to Vibrionaceae. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11012"
] | [
"DUF2850"
] | [
501
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
501
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF2850 | Protein of unknown function DUF2850 | DUF2850 | 1 |
IPR021272 | 21,272 | Protein of unknown function DUF2851 | DUF2851 | Family | 2,811 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11013"
] | [
"DUF2851"
] | [
2811
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Metazoa",
"unclassified sequences"
] | [
2731,
3,
77
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2851 | Protein of unknown function DUF2851 | DUF2851 | 1 |
IPR021273 | 21,273 | Protein of unknown function DUF2852 | DUF2852 | Family | 1,709 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11014"
] | [
"DUF2852"
] | [
1709
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
1694,
2,
13
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2852 | Protein of unknown function DUF2852 | DUF2852 | 4 |
IPR021274 | 21,274 | Protein of unknown function DUF2853 | DUF2853 | Family | 1,857 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11015"
] | [
"DUF2853"
] | [
1857
] | 1 | [] | [] | [] | 0 | [
"2pyq"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Ostreococcus tauri",
"ecological metagenomes"
] | [
1835,
1,
21
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2853 | Protein of unknown function DUF2853 | DUF2853 | 6 |
IPR021275 | 21,275 | Protein of unknown function DUF2854 | DUF2854 | Family | 1,184 | false | false | This family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF11016",
"PTHR35551"
] | [
"DUF2854",
""
] | [
1165,
1171
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Cyanobacteriota",
"Eukaryota"
] | [
362,
822
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
9,
2,
5
] | 3 | true | Family | Protein of unknown function DUF2854 | Protein of unknown function DUF2854 | DUF2854 | 8 |
IPR021276 | 21,276 | Protein of unknown function DUF2855 | DUF2855 | Family | 1,842 | false | false | This family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11017"
] | [
"DUF2855"
] | [
1842
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
1056,
729,
57
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2855 | Protein of unknown function DUF2855 | DUF2855 | 4 |
IPR021277 | 21,277 | Protein of unknown function DUF2610 | DUF2610 | Family | 165 | false | false | This family of proteins is functionally uncharacterised. They are predicted to contain a ribbon-helix-helix fold, so may function as DNA-binding proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11020"
] | [
"DUF2610"
] | [
165
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
157,
8
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2610 | Protein of unknown function DUF2610 | DUF2610 | 4 |
IPR021279 | 21,279 | Protein of unknown function DUF2721 | DUF2721 | Family | 4,147 | false | false | This family is conserved in bacteria. The function is not known. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11026"
] | [
"DUF2721"
] | [
4147
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriati",
"unclassified sequences"
] | [
4095,
6,
3,
43
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF2721 | Protein of unknown function DUF2721 | DUF2721 | 2 |
IPR021281 | 21,281 | Small nuclear RNA activating complex subunit 2 | SNAPC2 | Family | 676 | false | false | The SNAPc complex allows the transcription of human small nuclear RNA genes to occur by recognition of the proximal sequence element, the TATA box [ ]. SNAPC2 functions both to specifically recognise the proximal sequence element present in the core promoters of human snRNA genes and to stimulate TBP recognition of the... | [
"GO:0016251",
"GO:0009301"
] | [
"RNA polymerase II general transcription initiation factor activity",
"snRNA transcription"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PFAM",
"PANTHER"
] | [
"PF11035",
"PTHR15132"
] | [
"SNAPC2",
""
] | [
629,
639
] | 2 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-6807505",
"R-HSA-749476",
"R-HSA-76071",
"R-MMU-6807505",
"R-MMU-76071",
"R-RNO-6807505",
"R-RNO-76071"
] | [
"REACTOME:R-HSA-6807505",
"REACTOME:R-HSA-749476",
"REACTOME:R-HSA-76071",
"REACTOME:R-MMU-6807505",
"REACTOME:R-MMU-76071",
"REACTOME:R-RNO-6807505",
"REACTOME:R-RNO-76071"
] | 7 | [] | 0 | [
"PUB00053496",
"PUB00075226",
"PUB00098612"
] | [
"16603380",
"12621023",
"8633057"
] | [
"Co-expression of multiple subunits enables recombinant SNAPC assembly and function for transcription by human RNA polymerases II and III.",
"The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition.",
"The SNAP45 subunit of the small nuclear R... | [
2006,
2003,
1996
] | 3 | [] | [] | 0 | 0 | null | [
"Opisthokonta",
"bird metagenome"
] | [
675,
1
] | 2 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
4,
3,
6
] | 4 | true | Family | Small nuclear RNA activating complex subunit 2 | Small nuclear RNA activating complex subunit 2 | SNAPC2 | 5 |
IPR021282 | 21,282 | Dispersed gene family protein 1, domain 5 | Dispersed_gene_fam_prot1_dom5 | Domain | 824 | false | false | Dispersed gene family protein 1 (DGF-1) of Trypanosoma cruzi is one of the most abundant proteins in T. cruzi genome [ ]. It seems to have a preferential expression in amastigotes (intracellular replicative forms that develop in the mammalian host) [ ]. The function of this protein is not yet clear, however, it is like... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11038"
] | [
"DGF-1_5"
] | [
824
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00153905",
"PUB00153906"
] | [
"36839564",
"19841080"
] | [
"The Elusive <i>Trypanosoma cruzi</i> Disperse Gene Protein Family (DGF-1).",
"Localization and developmental regulation of a dispersed gene family 1 protein in Trypanosoma cruzi."
] | [
2023,
2010
] | 2 | [] | [] | 0 | 0 | null | [
"Trypanosoma"
] | [
824
] | 1 | [] | [] | 0 | true | Domain | Dispersed gene family protein 1, domain 5 | Dispersed gene family protein 1, domain 5 | Dispersed_gene_fam_prot1_dom5 | 9 |
IPR021283 | 21,283 | Bacteriophage baseplate wedge 1 protein | Phage_Wedge1 | Family | 1,950 | false | false | This entry, previously known as DUF2612, includes the baseplate wedge 1 protein of bacteriophage PhiTE that infects the plant pathogen Pectobacterium atrosepticum. Wedge 1 is a component of the wedge complex that comprises six lobed protomeric units in the baseplate. Each protomer contains a single copy of wedge 1 prot... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11041"
] | [
"Phage_Wedge1"
] | [
1950
] | 1 | [] | [] | [] | 0 | [
"7kh1",
"7yfz",
"8env",
"8eon",
"9b45",
"9cuy",
"9mjn"
] | 7 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
1560,
11,
368,
11
] | 4 | [] | [] | 0 | true | Family | Bacteriophage baseplate wedge 1 protein | Bacteriophage baseplate wedge 1 protein | Phage_Wedge1 | 2 |
IPR021284 | 21,284 | Protein of unknown function DUF2750 | DUF2750 | Family | 3,289 | false | false | This family is conserved in Proteobacteria. The function is not known. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11042"
] | [
"DUF2750"
] | [
3289
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Halorubrum tibetense",
"Hirondellea gigas",
"ecological metagenomes"
] | [
3276,
1,
1,
11
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF2750 | Protein of unknown function DUF2750 | DUF2750 | 9 |
IPR021285 | 21,285 | Transcription regulator, HycA | Tscrpt_reg_HycA | Family | 828 | false | false | This family is conserved in Proteobacteria. It is likely to be the transcriptional repressor molecule for the hyc and hyp operons, which express, amongst others, the protein HycA. This protein may be harnessed for the reduction of technetium oxide, an unwelcome product of radio-nucleotide bioaccumulation. HycA produces... | [] | [] | [] | 0 | [
"NCBIFAM",
"PFAM"
] | [
"NF007567",
"PF11046"
] | [
"PRK10198.1",
"HycA_repressor"
] | [
761,
828
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00003862",
"PUB00013159",
"PUB00053497",
"PUB00104498",
"PUB00104572",
"PUB00104573"
] | [
"8022272",
"1625581",
"17521447",
"12426353",
"10848985",
"15556475"
] | [
"Isolation and characterization of hypophosphite--resistant mutants of Escherichia coli: identification of the FocA protein, encoded by the pfl operon, as a putative formate transporter.",
"Mutational analysis of the operon (hyc) determining hydrogenase 3 formation in Escherichia coli.",
"Inhibition of hydrogen... | [
1994,
1992,
2007,
2002,
2000,
2004
] | 6 | [] | [] | 0 | 0 | null | [
"Ecdysozoa",
"Gammaproteobacteria"
] | [
2,
826
] | 2 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Transcription regulator, HycA | Transcription regulator, HycA | Tscrpt_reg_HycA | 7 |
IPR021286 | 21,286 | Baculovirus, protein E26 | Baculovirus_E26 | Family | 45 | false | false | DA26 (E26) is a multifunctional protein. One form of E26 associates with viral DNA or DNA binding proteins, while a second form associates with intracellular membranes [ ]. It functions to sort occlusion-derived virus envelope proteins to the inner nuclear membrane [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11050"
] | [
"Viral_env_E26"
] | [
45
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00053498",
"PUB00082321"
] | [
"17169392",
"19019955"
] | [
"BV/ODV-E26: a palmitoylated, multifunctional structural protein of Autographa californica nucleopolyhedrovirus.",
"Baculovirus data suggest a common but multifaceted pathway for sorting proteins to the inner nuclear membrane."
] | [
2007,
2009
] | 2 | [] | [] | 0 | 0 | null | [
"Alphabaculovirus"
] | [
45
] | 1 | [] | [] | 0 | true | Family | Baculovirus, protein E26 | Baculovirus, protein E26 | Baculovirus_E26 | 6 |
IPR021287 | 21,287 | Trans-sialidase, conserved site | Trans-sialidase_CS | Conserved_site | 2,995 | false | false | This is a highly conserved region, of about 50aa, that is the very C terminus of a number of more diverse proteins from Trypanosoma cruzi. All members of the family are annotated putatively as being trans-sialidase but this appears to be a diverse group. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11052"
] | [
"Tr-sialidase_C"
] | [
2995
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2995
] | 1 | [] | [] | 0 | true | Conserved_site | Trans-sialidase, conserved site | Trans-sialidase, conserved site | Trans-sialidase_CS | 6 |
IPR021288 | 21,288 | Sporulated oocyst TA4 antigen | Surface_antigen | Family | 477 | false | false | This family of proteins is a Eukaryotic family of surface antigens. One of the better characterised members of the family is the sporulated oocyst TA4 antigen from Eimeria tenella. The TA4 gene encodes a single polypeptide of 25kDa which contains a 17 and a 8kDa polypeptide [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11054"
] | [
"Surface_antigen"
] | [
477
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00053499"
] | [
"3290678"
] | [
"Characterization of a surface antigen of Eimeria tenella sporozoites and synthesis from a cloned cDNA in Escherichia coli."
] | [
1988
] | 1 | [] | [] | 0 | 0 | null | [
"Eimeriidae"
] | [
477
] | 1 | [] | [] | 0 | true | Family | Sporulated oocyst TA4 antigen | Sporulated oocyst TA4 antigen | Surface_antigen | 7 |
IPR021290 | 21,290 | Protein of unknown function DUF2861 | DUF2861 | Family | 515 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11060"
] | [
"DUF2861"
] | [
515
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Beauveria bassiana D1-5"
] | [
514,
1
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2861 | Protein of unknown function DUF2861 | DUF2861 | 3 |
IPR021291 | 21,291 | Cytochrome b6-f regulatory subunit PetP | Petp-like | Family | 423 | false | false | This family of proteins is predominantly found in cyanobacteria and red algae, including Uncharacterized protein ORF65 from Porphyra purpurea , Tsr0524 from Thermosynechococcus vestitus and Cytochrome b6-f regulatory subunit PetP. Tsr0524 (also known as PetP) is a component of the cyanobacterial cytochrome b6f that may... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11061"
] | [
"Tsr0524-like"
] | [
423
] | 1 | [] | [] | [] | 0 | [
"2n5u",
"7r0w"
] | 2 | [
"PUB00100692",
"PUB00162595"
] | [
"27033306",
"35726684"
] | [
"The cyanobacterial cytochrome b6f subunit PetP adopts an SH3 fold in solution.",
"Cryo-EM structures of the Synechocystis sp. PCC 6803 cytochrome b6f complex with and without the regulatory PetP subunit."
] | [
2016,
2022
] | 2 | [] | [] | 0 | 0 | null | [
"Cyanobacteriota",
"Rhodophyta",
"marine metagenome"
] | [
391,
31,
1
] | 3 | [] | [] | 0 | true | Family | Cytochrome b6-f regulatory subunit PetP | Cytochrome b6-f regulatory subunit PetP | Petp-like | 6 |
IPR021292 | 21,292 | Protein of unknown function DUF2863 | DUF2863 | Family | 987 | false | false | This bacterial family of proteins have no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11062"
] | [
"DUF2863"
] | [
987
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Linnemannia gamsii",
"metagenomes"
] | [
977,
2,
8
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2863 | Protein of unknown function DUF2863 | DUF2863 | 4 |
IPR021293 | 21,293 | Protein of unknown function DUF2865 | DUF2865 | Family | 1,424 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11064"
] | [
"DUF2865"
] | [
1424
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Alphaproteobacteria",
"ecological metagenomes"
] | [
1418,
6
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2865 | Protein of unknown function DUF2865 | DUF2865 | 6 |
IPR021294 | 21,294 | Protein of unknown function DUF2866 | DUF2866 | Family | 488 | false | false | This bacterial family of proteins have no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11065"
] | [
"DUF2866"
] | [
488
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Burkholderiaceae"
] | [
488
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF2866 | Protein of unknown function DUF2866 | DUF2866 | 4 |
IPR021295 | 21,295 | Protein of unknown function DUF2867 | DUF2867 | Family | 9,740 | false | false | This family contains uncharacterised proteins, including the single-pass membrane protein YbjT from Escherichia coli which has an N-terminal NAD(P)-binding domain. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11066"
] | [
"DUF2867"
] | [
9740
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes",
"virus sp. ctLpa4"
] | [
9511,
34,
194,
1
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF2867 | Protein of unknown function DUF2867 | DUF2867 | 3 |
IPR021296 | 21,296 | Protein of unknown function DUF2868 | DUF2868 | Family | 2,026 | false | false | Some members in this family of proteins with unknown function are annotated as putative membrane proteins. However, this cannot be confirmed. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11067"
] | [
"DUF2868"
] | [
2026
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
1997,
3,
26
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2868 | Protein of unknown function DUF2868 | DUF2868 | 9 |
IPR021297 | 21,297 | YlqD protein | YlqD | Family | 1,347 | false | false | The structure of a representative of this family has been solved and found to form a tetrameric structure of prefoldin-like architecture with the β-barrel core and helical coiled coil tentacles. This suggests that this family may act as molecular chaperones. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11068"
] | [
"YlqD"
] | [
1347
] | 1 | [] | [] | [] | 0 | [
"4dci"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
1335,
8,
4
] | 3 | [] | [] | 0 | true | Family | YlqD protein | YlqD protein | YlqD | 9 |
IPR021298 | 21,298 | Cilia- and flagella-associated protein 298 | CFAP298 | Family | 2,342 | false | false | This entry includes a group of cilia- and flagella-associated protein, including Kur from zebrafish and C21orf59 from humans. Kur has been shown to play a dual role in cilia motility and polarization [ ]. Primary ciliary dyskinesia (PCD) is caused when defects of motile cilia lead to chronic airway infections, male inf... | [
"GO:0003352"
] | [
"regulation of cilium movement"
] | [
"biological_process"
] | 1 | [
"PFAM",
"PANTHER"
] | [
"PF11069",
"PTHR13238"
] | [
"CFAP298",
""
] | [
2211,
2293
] | 2 | [] | [] | [] | 0 | [
"9k9m"
] | 1 | [
"PUB00089729",
"PUB00089805"
] | [
"24094744",
"26904945"
] | [
"Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia.",
"c21orf59/kurly Controls Both Cilia Motility and Polarization."
] | [
2013,
2016
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2342
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
5,
1,
22,
6,
4,
2,
2
] | 7 | true | Family | Cilia- and flagella-associated protein 298 | Cilia- and flagella-associated protein 298 | CFAP298 | 5 |
IPR021299 | 21,299 | Protein of unknown function DUF2871 | DUF2871 | Family | 1,456 | false | false | This family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11070"
] | [
"DUF2871"
] | [
1456
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Promethearchaeum syntrophicum",
"metagenomes"
] | [
1417,
34,
1,
4
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF2871 | Protein of unknown function DUF2871 | DUF2871 | 7 |
IPR021300 | 21,300 | Integrating conjugative element protein, PFL4695 | Integr_conj_element_PFL4695 | Family | 1,850 | false | false | This model describes a protein family exemplified by PFL_4695 of Pseudomonas fluorescens Pf-5. Full-length proteins in this family show some architectural variety, but this model represents a conserved domain. Most or all member proteins belong to laterally transferred chromosomal islands called integrative conjugative... | [] | [] | [] | 0 | [
"PFAM",
"NCBIFAM"
] | [
"PF11072",
"TIGR03765"
] | [
"DUF2859",
"ICE_PFL_4695"
] | [
1850,
1808
] | 2 | [
"GP"
] | [
"GenProp0855"
] | [
"GP:GenProp0855"
] | 1 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Gibberella intermedia",
"metagenomes"
] | [
1835,
1,
14
] | 3 | [] | [] | 0 | true | Family | Integrating conjugative element protein, PFL4695 | Integrating conjugative element protein, PFL4695 | Integr_conj_element_PFL4695 | 2 |
IPR021301 | 21,301 | Domain of unknown functionDUF2779 | DUF2779 | Domain | 1,424 | false | false | This domain is found at the C-terminal in Uncharacterized protein MG366, Uncharacterized protein UU173 and related bacteria. UU173 is encoded next to an element that encodes UU172 , a phase-variable surface membrane protein paralogous to multiple-banded antigen (MBA) [ ] | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11074"
] | [
"DUF2779"
] | [
1424
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00159629"
] | [
"21255110"
] | [
"Ureaplasma antigenic variation beyond MBA phase variation: DNA inversions generating chimeric structures and switching in expression of the MBA N-terminal paralogue UU172."
] | [
2011
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
12,
1272,
85,
55
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown functionDUF2779 | Domain of unknown functionDUF2779 | DUF2779 | 1 |
IPR021302 | 21,302 | Protein of unknown function DUF2780, VcgC/VcgE | DUF2780_VcgC/VcgE | Family | 1,532 | false | false | This is a bacterial family of uncharacterised proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11075"
] | [
"DUF2780"
] | [
1532
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
1514,
11,
7
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2780, VcgC/VcgE | Protein of unknown function DUF2780, VcgC/VcgE | DUF2780_VcgC/VcgE | 2 |
IPR021303 | 21,303 | Uncharacterised protein family, inner membrane, YbhQ | Uncharacterised_YbhQ | Family | 806 | false | false | This family is conserved in Proteobacteria. The function is not known but most members are annotated as being inner membrane protein YbhQ. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11076"
] | [
"YbhQ"
] | [
806
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"bioreactor metagenome"
] | [
805,
1
] | 2 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Uncharacterised protein family, inner membrane, YbhQ | Uncharacterised protein family, inner membrane, YbhQ | Uncharacterised_YbhQ | 1 |
IPR021305 | 21,305 | Protein of unknown function DUF2880 | DUF2880 | Family | 36 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11082"
] | [
"DUF2880"
] | [
36
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Cupriavidus"
] | [
36
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF2880 | Protein of unknown function DUF2880 | DUF2880 | 8 |
IPR021306 | 21,306 | Protein of unknown function DUF2878 | DUF2878 | Family | 2,632 | false | false | This bacterial family of proteins has no known function. Some members annotate the proteins as the permease component of a Mn2+/Zn2+ transport system however this cannot be confirmed. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11086"
] | [
"DUF2878"
] | [
2632
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
2605,
9,
18
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2878 | Protein of unknown function DUF2878 | DUF2878 | 3 |
IPR021307 | 21,307 | Protein of unknown function DUF2884 | DUF2884 | Family | 2,900 | false | false | Some members in this bacterial family of proteins are annotated as YggN which currently has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11101"
] | [
"DUF2884"
] | [
2900
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Fungi",
"marine sediment metagenome"
] | [
2892,
4,
4
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF2884 | Protein of unknown function DUF2884 | DUF2884 | 2 |
IPR021308 | 21,308 | Group 4 capsule polysaccharide formation lipoprotein GfcB | GfcB | Family | 2,978 | false | false | This family includes lipoprotein GfcB (YmcC), involved in group 4 capsule polysaccharide formation [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11102"
] | [
"YjbF"
] | [
2978
] | 1 | [] | [] | [] | 0 | [
"2in5"
] | 1 | [
"PUB00066719"
] | [
"16030220"
] | [
"Identification of an Escherichia coli operon required for formation of the O-antigen capsule."
] | [
2005
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"ecological metagenomes"
] | [
2960,
2,
16
] | 3 | [
"Escherichia coli (strain K12)"
] | [
2
] | 1 | true | Family | Group 4 capsule polysaccharide formation lipoprotein GfcB | Group 4 capsule polysaccharide formation lipoprotein GfcB | GfcB | 9 |
IPR021310 | 21,310 | Plant viral coat protein nucleocapsid | Nucleocap_ssRNA | Family | 360 | false | false | This family of nucleocapsid proteins is from ssRNA negative-strand viruses of plant origin. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11128"
] | [
"Nucleocap_ssRNA"
] | [
360
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Haploviricotina"
] | [
360
] | 1 | [] | [] | 0 | true | Family | Plant viral coat protein nucleocapsid | Plant viral coat protein nucleocapsid | Nucleocap_ssRNA | 7 |
IPR021311 | 21,311 | Rev protein of equine infectious anaemia virus | EIAV_Rev | Family | 376 | false | false | The sequence of this family is highly conserved and carries a nuclear export signal from residues 31-55, and RNA binding/nuclear localisation signals of RRDR at residue 76 and KRRRK at residue 159. Rev is an essential regulatory protein required for nucleocytoplasmic transport of incompletely spliced viral mRNAs that e... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11129"
] | [
"EIAV_Rev"
] | [
376
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Equine infectious anemia virus"
] | [
376
] | 1 | [] | [] | 0 | true | Family | Rev protein of equine infectious anaemia virus | Rev protein of equine infectious anaemia virus | EIAV_Rev | 1 |
IPR021312 | 21,312 | Protein of unknown function DUF2889 | DUF2889 | Family | 2,551 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11136"
] | [
"DUF2889"
] | [
2551
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
2469,
2,
80
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2889 | Protein of unknown function DUF2889 | DUF2889 | 4 |
IPR021313 | 21,313 | Protein of unknown function DUF2909 | DUF2909 | Family | 3,518 | false | false | This is a family of proteins conserved in Proteobacteria of unknown function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11137"
] | [
"DUF2909"
] | [
3518
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"unclassified sequences"
] | [
3469,
3,
46
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2909 | Protein of unknown function DUF2909 | DUF2909 | 5 |
IPR021314 | 21,314 | Protein of unknown function DUF2911 | DUF2911 | Family | 5,929 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11138"
] | [
"DUF2911"
] | [
5929
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"unclassified sequences",
"uncultured marine thaumarchaeote AD1000_39_D08"
] | [
5872,
4,
52,
1
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF2911 | Protein of unknown function DUF2911 | DUF2911 | 4 |
IPR021315 | 21,315 | Glycolipid exporter Gap/Sap | Gap/Sap | Family | 4,692 | false | false | This entry includes glycolipid exporters form bacteria and archaea, including peptidoglycolipid exporter Gap from Mycobacterium smegmatis and Sulfolipid-1 exporter Sap from Mycobacterium tuberculosis. Sap is required for the transport across the inner membrane of sulfolipid-1 (SL-1), which is a major cell wall lipid of... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11139"
] | [
"SfLAP"
] | [
4692
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00074523",
"PUB00077558"
] | [
"16194230",
"22194604"
] | [
"Gap, a mycobacterial specific integral membrane protein, is required for glycolipid transport to the cell surface.",
"Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis."
] | [
2005,
2012
] | 2 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"metagenomes"
] | [
92,
4561,
39
] | 3 | [] | [] | 0 | true | Family | Glycolipid exporter Gap/Sap | Glycolipid exporter Gap/Sap | Gap/Sap | 4 |
IPR021316 | 21,316 | Protein of unknown function DUF2913 | DUF2913 | Family | 1,845 | false | false | This family of proteins with unknown function appear to be restricted to Gammaproteobacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11140"
] | [
"DUF2913"
] | [
1845
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
1841,
4
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2913 | Protein of unknown function DUF2913 | DUF2913 | 6 |
IPR021317 | 21,317 | Protein of unknown function DUF2917 | DUF2917 | Family | 2,032 | false | false | This bacterial family of proteins appears to be restricted to Proteobacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11142"
] | [
"DUF2917"
] | [
2032
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"ecological metagenomes"
] | [
2022,
10
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2917 | Protein of unknown function DUF2917 | DUF2917 | 9 |
IPR021318 | 21,318 | Protein of unknown function DUF2919 | DUF2919 | Family | 1,970 | false | false | This entry represents a group of bacterial proteins, including the inner membrane protein YfeZ from E. coli. The function of YfeZ is not clear. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11143"
] | [
"DUF2919"
] | [
1970
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"marine sediment metagenome"
] | [
1969,
1
] | 2 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF2919 | Protein of unknown function DUF2919 | DUF2919 | 4 |
IPR021319 | 21,319 | SWEET-like domain | DUF2921 | Domain | 5,365 | false | false | This entry describes a domain of unknown function, which could adopt a similar fold to the SWEET-like (TM helices) domain. It was found in transmembrane E3 ubiquitin-proteins and members of the DSC E3 ubiquitin ligase complex. It is predominant in fungi and plants, including the FLY1/2 proteins from Arabidopsis thalian... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11145"
] | [
"DUF2921"
] | [
5365
] | 1 | [
"EC",
"METACYC"
] | [
"2.3.2.27",
"PWY-7511"
] | [
"EC:2.3.2.27",
"METACYC:PWY-7511"
] | 2 | [] | 0 | [
"PUB00150892",
"PUB00160282"
] | [
"23482858",
"39461958"
] | [
"Flying saucer1 is a transmembrane RING E3 ubiquitin ligase that regulates the degree of pectin methylesterification in Arabidopsis seed mucilage.",
"The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi."
] | [
2013,
2024
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
5365
] | 1 | [
"Arabidopsis thaliana",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea mays"
] | [
16,
1,
27,
1,
1,
16
] | 6 | true | Domain | SWEET-like domain | SWEET-like domain | DUF2921 | 6 |
IPR021320 | 21,320 | Protein of unknown function DUF2905 | DUF2905 | Family | 3,716 | false | false | This is a family of bacterial proteins conserved of unknown function. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF11146",
"PTHR36443"
] | [
"DUF2905",
""
] | [
3716,
2971
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
3649,
8,
59
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2905 | Protein of unknown function DUF2905 | DUF2905 | 4 |
IPR021321 | 21,321 | Protein of unknown function DUF2922 | DUF2922 | Family | 3,867 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11148"
] | [
"DUF2922"
] | [
3867
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Trichuris trichiura",
"unclassified sequences"
] | [
3815,
2,
50
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2922 | Protein of unknown function DUF2922 | DUF2922 | 1 |
IPR021322 | 21,322 | Protein of unknown function DUF2924 | DUF2924 | Family | 1,849 | false | false | This family of proteins has not been functionally characterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11149"
] | [
"DUF2924"
] | [
1849
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"metagenomes"
] | [
1812,
2,
16,
19
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF2924 | Protein of unknown function DUF2924 | DUF2924 | 8 |
IPR021324 | 21,324 | Protein of unknown function DUF2929 | DUF2929 | Family | 1,855 | false | false | This family of proteins with unknown function appears occur predominantly in Firmicutes. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11151"
] | [
"DUF2929"
] | [
1855
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"bioreactor metagenome"
] | [
1854,
1
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2929 | Protein of unknown function DUF2929 | DUF2929 | 3 |
IPR021325 | 21,325 | Cofactor assembly of complex C subunit B, CCB2/CCB4 | CCB2/CCB4 | Family | 1,955 | false | false | Cofactor maturation pathways such as the CCB system (system IV) for cytochrome c-heme attachment are conserved in all organisms performing oxygenic photosynthesis [ ]. The CCB system consists of four proteins: CCB1-4. CCB2 and CCB4 are paralogues derived from a unique cyanobacterial ancestor [ ]. Orthologues are conser... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11152"
] | [
"CCB2_CCB4"
] | [
1955
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00075312",
"PUB00075315"
] | [
"17535914",
"18593701"
] | [
"A specific c-type cytochrome maturation system is required for oxygenic photosynthesis.",
"A novel pathway of cytochrome c biogenesis is involved in the assembly of the cytochrome b6f complex in arabidopsis chloroplasts."
] | [
2007,
2008
] | 2 | [] | [
"IPR044705",
"IPR044970"
] | 0 | 2 | 0 | [
"Cyanobacteriota",
"Eukaryota"
] | [
362,
1593
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
11,
10,
11
] | 3 | true | Family | Cofactor assembly of complex C subunit B, CCB2/CCB4 | Cofactor assembly of complex C subunit B, CCB2/CCB4 | CCB2/CCB4 | 4 |
IPR021326 | 21,326 | Protein of unknown function DUF2931 | DUF2931 | Family | 2,684 | false | false | Some members in this family of proteins are annotated as lipoproteins however this cannot be confirmed. Currently, there is no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11153"
] | [
"DUF2931"
] | [
2684
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
2668,
3,
13
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2931 | Protein of unknown function DUF2931 | DUF2931 | 4 |
IPR021327 | 21,327 | Protein of unknown function DUF2934 | DUF2934 | Family | 4,946 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11154"
] | [
"DUF2934"
] | [
4946
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
4890,
4,
52
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2934 | Protein of unknown function DUF2934 | DUF2934 | 4 |
IPR021328 | 21,328 | Spore coat protein CotB-like | CotB-like | Family | 2,647 | false | false | This family of proteins, previously known as DUF2935, includes Spore coat protein CotB from Clostridioides difficile and similar sequences mainly found in firmicutes. CotB contributes to the formation of thick-exosporium spores [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11155"
] | [
"DUF2935"
] | [
2647
] | 1 | [] | [] | [] | 0 | [
"3d19",
"3dby"
] | 2 | [
"PUB00152825"
] | [
"36296193"
] | [
"Role of the Spore Coat Proteins <i>CotA</i> and <i>CotB</i>, and the Spore Surface Protein CDIF630_02480, on the Surface Distribution of Exosporium Proteins in <i>Clostridioides difficile</i> 630 Spores."
] | [
2022
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
2594,
4,
29,
20
] | 4 | [] | [] | 0 | true | Family | Spore coat protein CotB-like | Spore coat protein CotB-like | CotB-like | 3 |
IPR021329 | 21,329 | Protein of unknown function DUF2938 | DUF2938 | Family | 1,999 | false | false | This bacterial and archaeal family of proteins has no known function. Some members are thought to be membrane proteins, however this has not been confirmed. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11158"
] | [
"DUF2938"
] | [
1999
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"unclassified sequences"
] | [
1990,
9
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2938 | Protein of unknown function DUF2938 | DUF2938 | 5 |
IPR021330 | 21,330 | Protein of unknown function DUF2939 | DUF2939 | Family | 1,794 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11159"
] | [
"DUF2939"
] | [
1794
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Knufia peltigerae",
"metagenomes"
] | [
1789,
1,
4
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2939 | Protein of unknown function DUF2939 | DUF2939 | 9 |
IPR021331 | 21,331 | Hypervirulence associated protein, TUDOR domain | Hva1_TUDOR | Domain | 6,055 | false | false | Proteins containing this domain include HVA1 (hypervirulence-associated protein 1) from Cryptococcus neoformans ( ), whose absence is associated with a hypervirulent phenotype in mice. Metabolomics analysis suggests that when HVA1 is absent there is a block in the citric acid cycle, while structural analysis of the Hva... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11160"
] | [
"Hva1_TUDOR"
] | [
6055
] | 1 | [] | [] | [] | 0 | [
"4p5n"
] | 1 | [
"PUB00091033"
] | [
"27583447"
] | [
"A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals."
] | [
2016
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
4082,
1944,
13,
16
] | 4 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
2
] | 1 | true | Domain | Hypervirulence associated protein, TUDOR domain | Hypervirulence associated protein, TUDOR domain | Hva1_TUDOR | 3 |
IPR021332 | 21,332 | Protein of unknown function DUF2944 | DUF2944 | Family | 1,298 | false | false | This family of proteins with unknown function appear to be restricted to Proteobacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11161"
] | [
"DUF2944"
] | [
1298
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Ricinus communis",
"unclassified sequences"
] | [
1279,
1,
18
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2944 | Protein of unknown function DUF2944 | DUF2944 | 6 |
IPR021334 | 21,334 | Protein of unknown function DUF2947 | DUF2947 | Family | 669 | false | false | This family of proteins with unknown function appears to be restricted to Gammaproteobacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11163"
] | [
"DUF2947"
] | [
669
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"ecological metagenomes"
] | [
666,
3
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2947 | Protein of unknown function DUF2947 | DUF2947 | 3 |
IPR021335 | 21,335 | Protein of unknown function DUF2948 | DUF2948 | Family | 2,034 | false | false | This family of proteins with unknown function appear to be restricted to Proteobacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11164"
] | [
"DUF2948"
] | [
2034
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
2002,
2,
30
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2948 | Protein of unknown function DUF2948 | DUF2948 | 7 |
IPR021336 | 21,336 | Protein of unknown function DUF2949 | DUF2949 | Family | 807 | false | false | This family of proteins with unknown function appear to be restricted to Cyanobacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11165"
] | [
"DUF2949"
] | [
807
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
807
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF2949 | Protein of unknown function DUF2949 | DUF2949 | 6 |
IPR021337 | 21,337 | Protein of unknown function DUF2951 | DUF2951 | Family | 202 | false | false | This family of proteins has no known function. It has a highly conserved sequence. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11166"
] | [
"DUF2951"
] | [
202
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanobrevibacter arboriphilus",
"Viruses"
] | [
97,
1,
104
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2951 | Protein of unknown function DUF2951 | DUF2951 | 5 |
IPR021338 | 21,338 | Protein of unknown function DUF2953 | DUF2953 | Family | 2,530 | false | false | This family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11167"
] | [
"DUF2953"
] | [
2530
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Siphoviridae sp. ctf8W5",
"ecological metagenomes"
] | [
154,
2355,
1,
20
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF2953 | Protein of unknown function DUF2953 | DUF2953 | 3 |
IPR021340 | 21,340 | Protein of unknown function DUF2957 | DUF2957 | Family | 822 | false | false | Some members annotate the proteins to be putative lipoproteins however this cannot be confirmed. Currently no function is known for this family of proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11170"
] | [
"DUF2957"
] | [
822
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadati"
] | [
822
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF2957 | Protein of unknown function DUF2957 | DUF2957 | 1 |
IPR021341 | 21,341 | Protein of unknown function DUF2958 | DUF2958 | Family | 2,173 | false | false | Some members are annotated as lipoproteins however this cannot be confirmed. This family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11171"
] | [
"DUF2958"
] | [
2173
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"Methanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 / OCM 146 / M1)",
"metagenomes"
] | [
2073,
4,
5,
1,
90
] | 5 | [] | [] | 0 | true | Family | Protein of unknown function DUF2958 | Protein of unknown function DUF2958 | DUF2958 | 9 |
IPR021342 | 21,342 | Protein of unknown function DUF2959 | DUF2959 | Family | 1,103 | false | false | DUF2959 is a family of uncharacterised proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11172"
] | [
"DUF2959"
] | [
1103
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
1087,
4,
12
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2959 | Protein of unknown function DUF2959 | DUF2959 | 1 |
IPR021343 | 21,343 | Protein of unknown function DUF2960 | DUF2960 | Family | 548 | false | false | This family of proteins with unknown function appears to be restricted to Gammaproteobacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11173"
] | [
"DUF2960"
] | [
548
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"ecological metagenomes"
] | [
544,
4
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2960 | Protein of unknown function DUF2960 | DUF2960 | 5 |
IPR021344 | 21,344 | Protein of unknown function DUF2970 | DUF2970 | Family | 3,123 | false | false | This short family is conserved in Proteobacteria. The function is not known. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11174"
] | [
"DUF2970"
] | [
3123
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"unclassified sequences"
] | [
3082,
41
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2970 | Protein of unknown function DUF2970 | DUF2970 | 6 |
IPR021345 | 21,345 | GH172, second beta-sandwich domain | DUF2961 | Domain | 3,697 | false | false | This entry represents a domain found in GH172 family of enzymes including DFA I synthase/hydrolase from Bifidobacterium dentium , Exo-alpha-D-arabinofuranosidase from Microbacterium arabinogalactanolyticum and related proteins [ , , ]. These proteins contain a pair of homologous structurally similar domains which adopt... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11175"
] | [
"GH172_2nd"
] | [
3697
] | 1 | [] | [] | [] | 0 | [
"4kq7",
"7v1v",
"7v1w",
"7v1x",
"8ah3",
"8ic8"
] | 6 | [
"PUB00161976",
"PUB00161977",
"PUB00161978"
] | [
"37076525",
"37726269",
"34688653"
] | [
"Identification of D-arabinan-degrading enzymes in mycobacteria.",
"Identification and characterization of endo-α-, exo-α-, and exo-β-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria.",
"Identification of difructose dianhydride I synthase/hydrolase from an oral bacterium es... | [
2023,
2023,
2021
] | 3 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Halorubrum tailed virus 29",
"metagenomes"
] | [
14,
3274,
353,
1,
55
] | 5 | [] | [] | 0 | true | Domain | GH172, second beta-sandwich domain | GH172, second beta-sandwich domain | DUF2961 | 4 |
IPR021346 | 21,346 | Translation machinery-associated protein 16 | Tma16 | Family | 3,213 | false | false | Proteins in this family localise to the nucleus [ , ]. Their function is not clear. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF11176",
"PTHR13349"
] | [
"Tma16",
""
] | [
3211,
3130
] | 2 | [] | [] | [] | 0 | [
"2kkm",
"6lss",
"6lu8",
"8fla",
"8flb",
"8flc",
"8hfr",
"8idt",
"8idy",
"8ine",
"8inf"
] | 11 | [
"PUB00016470",
"PUB00035474"
] | [
"14562095",
"16702403"
] | [
"Global analysis of protein localization in budding yeast.",
"Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes."
] | [
2003,
2006
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
3213
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)"
] | [
2,
3,
6,
2,
1,
4,
1
] | 7 | true | Family | Translation machinery-associated protein 16 | Translation machinery-associated protein 16 | Tma16 | 5 |
IPR021347 | 21,347 | Protein of unknown function DUF2964 | DUF2964 | Family | 533 | false | false | This family of proteins with unknown function appears to be restricted to Proteobacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11177"
] | [
"DUF2964"
] | [
533
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Burkholderiaceae"
] | [
533
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF2964 | Protein of unknown function DUF2964 | DUF2964 | 4 |
IPR021348 | 21,348 | Domiain of unknown function DUF2963 | DUF2963 | Domain | 399 | false | false | This domain of unknown function is found mainly in Mollicutes. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11178"
] | [
"DUF2963"
] | [
399
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
399
] | 1 | [] | [] | 0 | true | Domain | Domiain of unknown function DUF2963 | Domiain of unknown function DUF2963 | DUF2963 | 6 |
IPR021349 | 21,349 | Protein of unknown function DUF2967 | DUF2967 | Family | 193 | false | false | This family of proteins with unknown function appears to be restricted to Drosophila. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11179"
] | [
"DUF2967"
] | [
193
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Neoptera"
] | [
193
] | 1 | [
"Drosophila melanogaster"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF2967 | Protein of unknown function DUF2967 | DUF2967 | 2 |
IPR021350 | 21,350 | Protein of unknown function DUF2968 | DUF2968 | Family | 996 | false | false | This family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11180"
] | [
"DUF2968"
] | [
996
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Pseudomonadota",
"metagenomes"
] | [
4,
985,
7
] | 3 | [
"Oryza sativa subsp. japonica"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF2968 | Protein of unknown function DUF2968 | DUF2968 | 2 |
IPR021351 | 21,351 | Protein of unknown function DUF2969 | DUF2969 | Family | 1,143 | false | false | This family of proteins with unknown function appears to be restricted to Lactobacillales. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11184"
] | [
"DUF2969"
] | [
1143
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
1139,
4
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2969 | Protein of unknown function DUF2969 | DUF2969 | 5 |
IPR021352 | 21,352 | Protein of unknown function DUF2971 | DUF2971 | Family | 4,465 | false | false | This bacterial family of proteins has no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11185"
] | [
"DUF2971"
] | [
4465
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
50,
4355,
6,
9,
45
] | 5 | [] | [] | 0 | true | Family | Protein of unknown function DUF2971 | Protein of unknown function DUF2971 | DUF2971 | 3 |
IPR021354 | 21,354 | Protein of unknown function DUF2975 | DUF2975 | Family | 8,913 | false | false | This family of bacterial proteins have no known function. These proteins are likely to be integral membrane proteins. The proteins contain a highly conserved glutamic acid close to their C terminus. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11188"
] | [
"DUF2975"
] | [
8913
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriati",
"unclassified sequences"
] | [
8838,
3,
5,
67
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF2975 | Protein of unknown function DUF2975 | DUF2975 | 8 |
IPR021355 | 21,355 | Bacteriophage Syn9, Gp224 | Phage_Syn9_Gp224 | Family | 439 | false | false | This entry represents a group of proteins from tailed bacteriophages and prophages mainly found in cyanobacteria, including from Bacteriophage Syn9, Gp224. Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently they have no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11189"
] | [
"DUF2973"
] | [
439
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes"
] | [
361,
78
] | 2 | [] | [] | 0 | true | Family | Bacteriophage Syn9, Gp224 | Bacteriophage Syn9, Gp224 | Phage_Syn9_Gp224 | 1 |
IPR021356 | 21,356 | Integrating conjugative element protein PFL4702 | Integr_conj_element_PFL4702 | Family | 1,709 | false | false | Members of this protein family are found occasionally on plasmids such as the Pseudomonas putida TOL plasmid pWWO_p085. Usually, however, they are found on the bacterial main chromosome in a region flanked by markers of conjugative transfer and/or transposition. | [] | [] | [] | 0 | [
"PFAM",
"NCBIFAM"
] | [
"PF11190",
"TIGR03745"
] | [
"DUF2976",
"conj_TIGR03745"
] | [
1709,
1610
] | 2 | [
"GP"
] | [
"GenProp0855"
] | [
"GP:GenProp0855"
] | 1 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
1694,
2,
13
] | 3 | [] | [] | 0 | true | Family | Integrating conjugative element protein PFL4702 | Integrating conjugative element protein PFL4702 | Integr_conj_element_PFL4702 | 6 |
IPR021357 | 21,357 | Protein of unknown function DUF2782 | DUF2782 | Family | 1,985 | false | false | This is a bacterial family of proteins whose function is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11191"
] | [
"DUF2782"
] | [
1985
] | 1 | [] | [] | [] | 0 | [
"2mhg"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Knufia peltigerae",
"Pseudomonadati",
"unclassified sequences"
] | [
1,
1952,
32
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2782 | Protein of unknown function DUF2782 | DUF2782 | 2 |
IPR021358 | 21,358 | Protein of unknown function DUF2977 | DUF2977 | Family | 262 | false | false | This entry includes Bacteriophage 96, Orf38. The characteristics of the protein distribution suggest prophage matches in addition to the phage matches. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11192"
] | [
"DUF2977"
] | [
262
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Viruses"
] | [
114,
148
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2977 | Protein of unknown function DUF2977 | DUF2977 | 8 |
IPR021359 | 21,359 | Protein of unknown function DUF2812 | DUF2812 | Family | 3,375 | false | false | This is a bacterial family of uncharacterised proteins, however some members of this family are annotated as membrane proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11193"
] | [
"DUF2812"
] | [
3375
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanobacteriota",
"metagenomes"
] | [
3338,
8,
29
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2812 | Protein of unknown function DUF2812 | DUF2812 | 2 |
IPR021361 | 21,361 | Thoeris anti-defense 2-like domain | Tad2-like_dom | Domain | 2,119 | false | false | This entry represents Thoeris anti-defense 2 from Bacillus phage SP01 (Tad2) and similar sequences from tailed bacteriophages and bacterial prophagues. Tad2 is an anti-defence protein that counteracts the host Thoeris antiviral defence system. It sequesters the immune signalling molecules produced by Thoeris TIR-domain... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11195"
] | [
"Tad2-like"
] | [
2119
] | 1 | [] | [] | [] | 0 | [
"8kbi",
"8kbj",
"8kbk",
"8kbl",
"8kbm",
"8sme",
"8smf",
"8smg",
"8v3e",
"8wjc",
"8wjd",
"8wje",
"9eib"
] | 13 | [
"PUB00153732"
] | [
"37992756"
] | [
"Phages overcome bacterial immunity via diverse anti-defence proteins."
] | [
2024
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eumetazoa",
"Methanobacteriota",
"Viruses",
"metagenomes"
] | [
1790,
2,
2,
297,
28
] | 5 | [] | [] | 0 | true | Domain | Thoeris anti-defense 2-like domain | Thoeris anti-defense 2-like domain | Tad2-like_dom | 7 |
IPR021363 | 21,363 | Protein of unknown function DUF2835 | DUF2835 | Family | 1,363 | false | false | This is a bacterial family of uncharacterised proteins. One member of this family ( ) is annotated as the A subunit of Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV). | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11197"
] | [
"DUF2835"
] | [
1363
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"unclassified sequences"
] | [
1331,
32
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF2835 | Protein of unknown function DUF2835 | DUF2835 | 5 |
IPR021364 | 21,364 | Protein of unknown function DUF2857 | DUF2857 | Family | 1,845 | false | false | This is a bacterial family of uncharacterised proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11198"
] | [
"DUF2857"
] | [
1845
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Pseudomonadota",
"metagenomes"
] | [
5,
1826,
14
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2857 | Protein of unknown function DUF2857 | DUF2857 | 8 |
IPR021365 | 21,365 | Protein of unknown function DUF2891 | DUF2891 | Family | 2,852 | false | false | This is a bacterial family of uncharacterised proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11199"
] | [
"DUF2891"
] | [
2852
] | 1 | [] | [] | [] | 0 | [
"8ieu",
"8iev"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriati",
"ecological metagenomes"
] | [
2683,
70,
73,
26
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF2891 | Protein of unknown function DUF2891 | DUF2891 | 5 |
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