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" curcumin is herbal compound that has been shown to have anticancer effects in preclinical andclinical studies the anticancer effects of curcumin include inhibiting the carcinogenesis inhibiting angiogenesisand inhibiting tumour growth this study aims to determine the clinical effects of curcumin in different types o... | Colon_Cancer |
" leukotriene receptor antagonists ltras are broadly used for the management of allergic asthmaand have recently been indicated to inhibit carcinogenesis and cancer cell growth in colorectal cancer crcchemoprevention studies the occurrence of adenoma or crc itself is generally set as the trial endpoint althoughthe occ... | Colon_Cancer |
ovarian cancer is one of the leading causes of common lethal gynecologic malignancy cortez in worldwide there were an estimated cases and deaths from ovariancancer bray because of the lack of an early diagnosis method and the absence ofspeciï¬c early warning symptoms patients with ovarian cancer are usually di... | Colon_Cancer |
introduction postoperative ileus poi a common complication after surgery severely affects postoperative recovery it is unclear whether pretreatment with transcutaneous electrical acupoint stimulation teas can improve recovery from poi this trial will evaluate the effects of pretreatment with teas on poimethods and ana... | Colon_Cancer |
" recently copy number alteration cna of 9p241 were demonstrated in of diffuse large bcelllymphoma dlbcl with gene expression and mutation profiles that were similar to those of primary mediastinallarge bcell lymphoma pmbcl however their cnabased profile and clinical impact still remain unclearmethods multiplex ligat... | Colon_Cancer |
continuously increasing with development of the economy and the environment [] the prognosis for hcc patients remains extremely poor although significant progress has been achieved strategies for early diagnosis are urgently needed because the majority of patients with hcc are diagnosed in very late stages however the... | Colon_Cancer |
" breast cancer bc is the most commonly diagnosed malignant cancer in women bc is the main cause of cancerrelated death in women and seriously threatens the life and health of women worldwide micrornas mirnasmirs have been reported to regulate the development and progression of different types of cancer however the reg... | Colon_Cancer |
purposeconjunctival squamous cell carcinoma scc is primarily treated with surgical resectionscc has various stages and local recurrence is common the purpose of this study was todetermine molecular localization of epidermal growth factor receptor egfr and the possibility of egfr as a biomarker for the management of con... | Colon_Cancer |
" levels of physical activity change throughout the year however little is known to what extentactivity levels can vary based on accelerometer determined sedentary and physicallyactive time the aim of thislongitudinal study was to examine older adults activity changes from a nonsnowfall season to a subsequentsnowfall... | Colon_Cancer |
thyroid carcinoma is presently the malignancy with the most rapidly increasing incidence in the worldand is the most widely recognized endocrine carcinoma in the western world thyroid cancers derivedfrom follicular thyroid cells can be sorted into papillary thyroid carcinoma ptc follicular thyroid carcinoma ftc and a... | Colon_Cancer |
glioma initiates from glial cells and contains several types such as astrocytoma and oligodendroglioma1 over a quarter of brain tumors are glioma which causes a large number of cancerrelated deaths every year around the world1 the current clinically therapeutic strategies are surgery combined with che... | Colon_Cancer |
chronic rhinosinusitis crs characterized by dysfunctionalmucociliary clearancemcc with subsequent microbialcolonization is known as a multifactorial disease process wherebacterial infection may play a role in the commencement orprogression of the ammatory response ramakrishnan crs patients have complex sinus microbi... | Colon_Cancer |
" the activation of the nfκb pathway plays a crucial role in the progression of breast cancer bca andalso involved in endocrine therapy resistance on the contrary to the canonical nfκb pathway the effect of thenoncanonical nfκb pathway in bca progression remains elusivemethods bca tumor tissues and the correspondin... | Colon_Cancer |
chronic rhinosinusitis crs characterized by dysfunctionalmucociliary clearancemcc with subsequent microbialcolonization is known as a multifactorial disease process wherebacterial infection may play a role in the commencement orprogression of the ammatory response ramakrishnan crs patients have complex sinus microbi... | Colon_Cancer |
craigpattersontelecaretoj rajani r perry m the reality of medical work the case for a new perspectiveon telemedicine virtual real bf01421807 hoek pd schers hj bronkhorst em vissers kcp hasselaar jgj the eï¬ectof weekly specialist palliative care teleconsultations in patients with advancedcancer a randomized clini... | Colon_Cancer |
high throughput methods in biological and biomedical fields acquire alarge number of molecular parameters or omics data by a single experimentcombining these omics data can significantly increase the capability for recoveringfinetuned structures or reducing the effects of experimental and biological noise indataresul... | Colon_Cancer |
" inhibiting suchtarget protein reduces the virulence of pathogens and reduces thetherapeutic resistance in the case of cancer we first come to the basicunderstanding of the role of grp78 in healthy and diseased cells grp78 in normal versus stressed cellunder normal conditions grp78 is found bound to three essentialenz... | Colon_Cancer |
" colorectal cancer crc is the third leading cause of cancerassociated mortality the present study aimed to investigate novel biomarkers to predict prognosis and provide a theoretical basis for studies of the pathogenesis and the development of therapies for crc the present study compared mrna expression levels of pat... | Colon_Cancer |
this study hypothesizes that bromelain bl acts as radiosensitizer of tumor cells and that it protects normal cells from radiation effects in vitro and in vivo studies have been carried out to prove that assumption in vitro mtt cell proliferation assay has shown that the irradiated ehrlich ascites carcinoma eac cell lin... | Colon_Cancer |
"carcinogenesis is a process of somatic evolution previous models of stem and transient amplifying cells in epithelial proliferating units like colonic crypts showed that intermediate numbers of stem cells in a crypt should optimally prevent progression to cancer if a stem cell population is too small it is easy for a ... | Colon_Cancer |
" in head and neck cancer hnc the relationship between a delay in starting radiotherapy rt andthe outcome is unclear the aim of the present study was to determine the impact of the amount of time beforetreatment intervention tti and the growth kinetics of individual tumors on treatment outcomes and survivalmethods two... | Colon_Cancer |
dysregulation of lncrnas is frequent in glioma and has emerged as an important mechanism involved in tumorigenesis previous analysis of chinese glioma genome atlas cgga database indicated that lbx2as1 expression is one of differentially expression lncrna between lower grade glioma lgg grade ii and iii and glioblast... | Colon_Cancer |
covid19 has had an impact on the provision of colorectal cancer care the aim of the crccovid study is to describe the changes in colorectal cancer services in the uk and usa in response to thepandemic and to understand the longterm impactmethods and analysis this study comprises phases phase is a survey of colorecta... | Colon_Cancer |
cancer is a complex and heterogeneous disease with many possible genetic and environmentalcauses the same treatment for patients of the same cancer type often results in different outcomes in terms ofefficacy and side effects of the treatment thus the molecular characterization of individual cancer patients isincreas... | Colon_Cancer |
" according to the who most chronic diseases including cancer can be prevented by identifyingtheir risk factors such as unhealthy diet smoking and physical inactivity this research examined the effectiveness ofa theorybased educational intervention on colorectal cancerrelated preventive nutritional behaviors among asa... | Colon_Cancer |
" the incidence of thyroid carcinoma is increasing all over the world some studies have suggestedthat the change of adipokines expression can induce thyroid carcinoma however other studies have come to theopposite therefore we studied the relationship between adipokines and thyroid carcinomamethods databasespubmed c... | Colon_Cancer |
collagen triple helix repeat containing1 cthrc1 anextracellular matrix ecm protein was identiï¬ed in thescreening of diï¬erentially expressed sequences between balloon injury and normal arteries the evolution of cthrc1can be traced back to at least million years ago and theconserved genes were not found in invertebra... | Colon_Cancer |
dysregulation of lncrnas is frequent in glioma and has emerged as an important mechanism involved in tumorigenesis previous analysis of chinese glioma genome atlas cgga database indicated that lbx2as1 expression is one of differentially expression lncrna between lower grade glioma lgg grade ii and iii and glioblast... | Colon_Cancer |
" the severe acute respiratory syndrome coronavirus sarscov2 has caused the greatest worldwide pandemic since the flu the consequences of the coronavirus disease covid19 are devastating and represent the current major public health issue across the globe at the onset sarscov2 primarily attacks the respiratory syste... | Colon_Cancer |
" phytolaccaceae species in china are not only ornamental plants but also perennial herbs that areclosely related to human health however both largescale fulllength cdna sequencing and reference genevalidation of phytolaccaceae members are still lacking therefore singlemolecule realtime sequencing technologywas employ... | Colon_Cancer |
" the activation of the nfκb pathway plays a crucial role in the progression of breast cancer bca andalso involved in endocrine therapy resistance on the contrary to the canonical nfκb pathway the effect of thenoncanonical nfκb pathway in bca progression remains elusivemethods bca tumor tissues and the correspondin... | Colon_Cancer |
" in head and neck cancer hnc the relationship between a delay in starting radiotherapy rt andthe outcome is unclear the aim of the present study was to determine the impact of the amount of time beforetreatment intervention tti and the growth kinetics of individual tumors on treatment outcomes and survivalmethods two... | Colon_Cancer |
" mirnas regulate a multitude of cellular processes and their aberrant regulation is linked to humancancer however the role of mir4255p in lung cancer lca is still largely unclear here we explored the role ofmir4255p during lca tumorigenesismethods cell proliferation was evaluated by cell counting kit8 and colony form... | Colon_Cancer |
acute myeloid leukemia aml is the most common type ofacute leukemia in adults caused by the clonal expansion ofundiï¬erentiated myeloid progenitor cells although mostpatients with aml can achieve complete remission by inductionchemotherapy the recurrence rate remains high and thus is themain factor aï¬ecting the outco... | Colon_Cancer |
"what clinicians know about the diagnosis treatment and prevention of disease originates from studies mostly done on male cells male mice and men1 historically for multiple reasons including the purported safety of women and their offspring women of childbearing age were excluded from clinical ... | Colon_Cancer |
" excessive perioperative fluid administration may result in iatrogenic endothelial dysfunction andtissue edema transducing inflammatory markers into the bloodstream colloids remain longer in the circulationrequiring less volume to reach similar hemodynamic endpoints compared to crystalloids thus we tested thehypothes... | Colon_Cancer |
section all disclosure information for gie editors can befound online at httpwwwgie contentconï¬ictoï¬nterest cme editors and their disclosures are as followsprasad g iyer md associate editor for cmeconsultingadvisoryspeaking olympus research supporttakeda pharmaamit rastogi md associate editor for cmeconsulting... | Colon_Cancer |
" african americans aa are at high risk for colorectal cancer crc studies report a increasein crc risk with physical inactivity obesity and metabolic syndrome activation of the wntcatenin ctnnb1signaling pathway plays a critical role in colorectal carcinogenesis accumulating evidence also indicates a role ofwntctnnb... | Colon_Cancer |
clinical manifestations of sarscov2 infection include more frequently fever and cough failure can occur in persons with additional comorbidities liver dysfunction is one of the most striking affections among patients suggesting that sarscov2 may represent a new king of liver aggressor however the molecular process un... | Colon_Cancer |
preoperative heart rate variability a prognosticindicator for overall survival and cancer recurrencein patients with primary colorectal cancer one e0237244 101371 pone0237244editor louise emilsson university of oslonorwayreceived february accepted july published august copyright strous this is an openaccess di... | Colon_Cancer |
in a novel coronavirus sarscov2 was found to cause a highly contagious disease characterized by pneumonia the disease covid19 quickly spread around the globe escalating to a global pandemic in this review we discuss the virological immunological and imaging approaches harnessed for covid19 diagnosis and research covid... | Colon_Cancer |
during the covid19 pandemic emergency departments have noted a significant decrease in strokepatients we performed a timely analysis of the bavarian telestroke tempis working diagnosis databasemethods twelve hospitals from the tempis network were selected data collected for january through april in years through we... | Colon_Cancer |
" the ampactivated protein kinase ampk is an evolutionarily conserved regulator of cellular energyhomeostasis as a nexus for transducing metabolic signals ampk cooperates with other energysensing pathwaysto modulate cellular responses to metabolic stressors with metabolic reprogramming being a hallmark of cancerthe ut... | Colon_Cancer |
"adipogenesis is the process through which mesenchymalstem cells mscs commit to the adipose lineage and diï¬erentiate into adipocytes during this process preadipocytescease to proliferate begin to accumulate lipid droplets anddevelop morphologic and biochemical characteristics ofmature adipocytes such as hormonerespons... | Colon_Cancer |
endometrial cancer ec is a common malignancy of the female reproductive system circular rnas circrnas were demonstrated to exert critical roles in cancers including ec this study aimed to investigate the effects of hsa_circrna_0001776 circ_0001776 on ecmethods realtime quantitative pcr rtqpcr was used to measure c... | Colon_Cancer |
the european commission asked efsa for a scientiï¬c opinion on the risks for animal and humanhealth related to the presence of glycoalkaloids gas in feed and food this risk assessment coversedible parts of potato plants and other food plants containing gastomato andaubergine in humans acute toxic effects of potato gas... | Colon_Cancer |
gastroenteropancreatic neuroendocrine neoplasms gep nens as well as neuroendocrine tumors gep nets are heterogeneous tumors that originate from peptidergic neurons and neuroendocrine cells previously described as carcinoid tumors in most nets are indolent tumors compared with other epithelial malignancies h... | Colon_Cancer |
"ammatory bowel disease ibd is a long life disease with remission and relapse periods ibd arises as a result of inappropriateimmune response to intestinal commensal anisms in individualswith genetic predisposition and consequently causes ammation andintestinal ulcers in addition ibd has a complex pathogenesis andma... | Colon_Cancer |
ulcerative colitis is a type of ammatory bowel disease thatcan potentially lead to cancer e age of onset of colitis istypically years old and it can seriously threaten thequality of life of patients e immunopathogenesis andimmunosuppressive treatment of colitis are currently theresearch topics of significant inter... | Colon_Cancer |
primary colorectal cancer pcrc is a common digestive tract cancer in the elderly the primary lesioncan be seen in the left colon the right colon the upper or lower rectum pcrc is the second mostcommonly diagnosed cancer in women and the third most commonly diagnosed cancer in men and theprevalence of male is higher t... | Colon_Cancer |
"high mobility group box hmgb1 is a nonhistone chromatinassociated protein widely distributed in eukaryoticcells and is involved in dna damage repair and genomic stability maintenance in response to stimulus like bacteriaor chemoradiotherapy hmgb1 can translocate to extracellular context as a danger alarmin activate t... | Colon_Cancer |
" immune checkpoint inhibitors that block programmed cell death1 pd1 and programmed cell death ligand1 pd l1 have improved outcomes for many cancer subtypes but do exhibit toxicity in the form of immune related adverse eventsobjective the aim of this study was to investigate the emerging toxicities of pd1 and pd l1 ... | Colon_Cancer |
coronaviruses covs belong to a family of envelopedviruses with a positive sense singlestranded rna genomecovs cause illness ranging from upper respiratory tractinfections urtis resembling the common cold to lowerrespiratory tract infections lrtis such as bronchitis pneumonia and even severe acute respiratory syndrome s... | Colon_Cancer |
" the practice of clinical radiology has become more sedentary in the era of the picture archiving andcommunication system physical inactivity is a wellknown risk factor for various chronic diseases this study aimedto determine the frequency and pattern of physical exercises among radiologists in the eastern province ... | Colon_Cancer |
" clinical trials have been conducted to clarify the beneficial effects of vd3 1α25dihydroxy vitamind3 also known as calcitriol treatment in prostate cancer however the molecular mechanisms underlying theseeffects are not fully understood recent studies on igfbp3 have indicated its intracellular functions in cell gro... | Colon_Cancer |
open accesscitation iburg km mikkelsen l adair t lopez ad are cause of death data fit for purposeevidence from countries at different levels ofsocioeconomic development one e0237539 101371 pone0237539editor brecht devleesschauwer sciensanobelgiumreceived april accepted july published august peer review history re... | Colon_Cancer |
"cellular recognition of microbial dna is an evolutionarily conserved mechanism by which the innate immunesystem detects pathogens cyclic gmpamp synthase cgas and its downstream effector stimulator of interferongenes sting are involved in mediating fundamental innate antimicrobial immunity by promoting the release ofty... | Colon_Cancer |
emerging evidence reveals that micrornas mirnas play a crucial role in tumor progression but the underlying mechanism of micrornas in lung squamous cell cancer lscc remains unclearmethod westernblotting and quantitative realtime pcr qpcr were carried out to detect mrna and protein expression cell proliferation was... | Colon_Cancer |
covid19 has had an impact on the provision of colorectal cancer care the aim of the crccovid study is to describe the changes in colorectal cancer services in the uk and usa in response to thepandemic and to understand the longterm impactmethods and analysis this study comprises phases phase is a survey of colorecta... | Colon_Cancer |
" chemotherapy is one of the most commonly used treatments for patients with advanced colon cancer yet the toxicity of chemotherapy agents such as fluorouracil 5fu limits the effectiveness of chemotherapy ginsenoside rg3 rg3 is an active ingredient isolated from ginseng rg3 has been shown to display anticancer effects... | Colon_Cancer |
gon§ales junior w effect of treatment with injectable progesterone at the onset of super precocious tairessincronization protocol on tai pregnancy rates of nellore heifers in animal reproduction for the annual meeting of the brazilian embryo technology society sbte august florianopolis brazil animal reproducti... | Colon_Cancer |
s case reports duplicate studies and those with insufficient available data were excludeddata extraction and managementdata were independently extracted by two investigators yao xl and wu ww according to the same inclusionand exclusion criteria disagreements were adjudicated by a third reviewer qu kthe following data w... | Colon_Cancer |
"melatonin is a sleepregulating hormone created by the pineal glandand is released at night it has been found to have biological activityin almost all living anisms including plants animals and microbes itcan quickly enter cells through the bilipid bilayer and exhibit scavenging activity towards oxygen free radicals ... | Colon_Cancer |
objective this study aimed to test the hypothesis that levobupivacaine has antitumour effects on breast cancer cellsresults colony formation and transwell assay were used to determine breast cancer cells proliferation flow cytometry annexin v and pi staining was used to investigate breast cancer cells apoptosis th... | Colon_Cancer |
" exercise has been extensively utilised as an effective therapy for overweight and obesityassociatedchanges that are linked to health complications several preclinical rodent studies have shown that treadmillexercise alongside an unhealthy diet improves metabolic health and microbiome composition furthermorechronic e... | Colon_Cancer |
"gut microbiota composition influences the balance between human health and disease increasing evidencesuggests the involvement of microbial factors in regulating cancer development progression and therapeuticresponse distinct microbial species have been implicated in modulating gut environment and architecture thataff... | Colon_Cancer |
" among eukaryotic anisms alternative splicing is an important process that can generate multipletranscripts from one same precursor messenger rna which greatly increase transcriptome and proteome diversitythis process is carried out by a superprotein complex defined as the spliceosome specifically splicing factor bra... | Colon_Cancer |
"although the clinical development of immune checkpoint inhibitors icis therapy has ushered in a new era of antitumor therapy with sustained responses and significant survival advantages observed in multiple tumors mostpatients do not benefit therefore more and more attention has been paid to the identification and dev... | Colon_Cancer |
ammation is an established risk factor for colorectal cancer we and others have shown that colorectal cancerpatients with elevated cysteinyl leukotriene receptor cyslt2r and 15hydroxyprostaglandin dehydrogenase15pgdh levels exhibit good prognoses however both cyslt2r and 15pgdh which act as tumour suppressorsare ofte... | Colon_Cancer |
" preproof 0c highlights f0b7 propolis made by bees from bioactive plant resins has antiviral activity f0b7 propolis potentially can interfere with host cell invasion by sarscov2 f0b7 propolis blocks proinflammatory pak1 a kinase highly expressed in covid19 patients propolis a resinous material produced by ... | Colon_Cancer |
"pd1pdl1 blockade therapy is a promising cancer treatment strategy which has revolutionized the treatmentlandscape of malignancies over the last decade pd1pdl1 blockade therapy has been trialed in a broad range ofmalignancies and achieved clinical success despite the potentially curelike survival benefit only a minorit... | Colon_Cancer |
curative therapeutic options for a number of immunological disorders remain to be established and approaches for identifying drug candidates are relatively limited furthermorephenotypic screening methods using induced pluripotent stem cell ipscderived immunecells or hematopoietic cells need improvement in the present s... | Colon_Cancer |
coronaviruses covs belong to a family of envelopedviruses with a positive sense singlestranded rna genomecovs cause illness ranging from upper respiratory tractinfections urtis resembling the common cold to lowerrespiratory tract infections lrtis such as bronchitis pneumonia and even severe acute respiratory syndrome s... | Colon_Cancer |
" fasassociated factor faf1 has been implicated in parkinsons disease pd and activates the celldeath machinery in the cytosol however the presence of extracellular faf1 has not been studiedmethods serumfree conditioned medium cm from faf1transfected shsy5y cells was concentrated andanalyzed by western blotting exoso... | Colon_Cancer |
" mirnas regulate a multitude of cellular processes and their aberrant regulation is linked to humancancer however the role of mir4255p in lung cancer lca is still largely unclear here we explored the role ofmir4255p during lca tumorigenesismethods cell proliferation was evaluated by cell counting kit8 and colony form... | Colon_Cancer |
" accurate detection of patients with minimal residual disease mrd after surgery for stage ii coloncancer cc remains an urgent unmet clinical need to improve selection of patients who might benefit formadjuvant chemotherapy act presence of circulating tumor dna ctdna is indicative for mrd and has highpredictive value ... | Colon_Cancer |
agar oligosaccharides aos produced by agarase has a good application prospect agar amarine polysaccharide producing from red algae is widely used in food industry pharmaceuticalindustry and biological engineering wonjae as the main component of agaragarose is composed of 36anhydrolgalactose lahg and dgalactose dgal ... | Colon_Cancer |
" variability in the health effects of dietary fiber might arise from interindividual differences in the gutmicrobiotas ability to ferment these substrates into beneficial metabolites our understanding of what drives thisindividuality is vastly incomplete and will require an ecological perspective as microbiomes func... | Colon_Cancer |
" a critical barrier to improving the quality of endoflife eol cancer care is our lack of understanding of themechanisms underlying variation in eol treatment intensity this study aims to fill this gap by identifying anizational and provider practice norms at major us cancer centers and how these norms influence prov... | Colon_Cancer |
" vibrio cholerae are oxidasepositive bacteria that are classified into various serotypes based on the osurface antigen v cholerae serotypes are divided into two main groups the o1 and o139 group and the nono1nono139 group o1 and o139 v cholerae are related to cholera infection whereas nono1nono139 v choleraenovc can ... | Colon_Cancer |
neprilysin nep is a neutral endopeptidase it is also known by different functional names such as common acute lymphoblastic leukemia antigen calla the cluster of differentiation cd10 endoprotease endopeptidase and membrane metalloen dopeptidase nep is a member of m13 family of zinc peptidase in ... | Colon_Cancer |
bcl9 and pygo are bcatenin cofactors that enhance the transcription of wnt targetgenes they have been proposed as therapeutic targets to diminish wnt signaling output inintestinal malignancies here we find that in colorectal cancer cells and in developing mouseforelimbs bcl9 proteins sustain the action of bcatenin in ... | Colon_Cancer |
colorectal carcinoma crc as one of the most commongastrointestinal malignancies has developed the worldsfourth most deadly cancer with a high rate of incidence andmortality [ ] liver metastasis which is the most commonform for crc metastasis is the leading cause of high mortality for this severe malignancy however f... | Colon_Cancer |
"introduction a diet low in fermentable oligosaccharides disaccharides monosaccharides and polyols fodmap is an effective way to reduce gut symptoms in people with irritable bowel syndrome ibs this diet reduces the intake of fermentable fibres leading to changes of the gut microbiota and insufficient fermentation in t... | Colon_Cancer |
subcutaneous hydration and medicationsinfusions effectiveness safety acceptability asystematic review of systematic reviews one e0237572 101371 pone0237572editor jose´ das neves university of portoportugalreceived november accepted july published august copyright broadhurst this is an openaccess distributed un... | Colon_Cancer |
it is hard to comprehend how much of their lives poor people spend waiting in the emergency room dealing with indifferent bureaucracies that are supposed to address basic needs in the laundromat where people must scramble for available machines and keep a close eye on their laundry waiting adds yet more pressu... | Colon_Cancer |
this study hypothesizes that bromelain bl acts as radiosensitizer of tumor cells and that it protects normal cells from radiation effects in vitro and in vivo studies have been carried out to prove that assumption in vitro mtt cell proliferation assay has shown that the irradiated ehrlich ascites carcinoma eac cell lin... | Colon_Cancer |
"adipogenesis is the process through which mesenchymalstem cells mscs commit to the adipose lineage and diï¬erentiate into adipocytes during this process preadipocytescease to proliferate begin to accumulate lipid droplets anddevelop morphologic and biochemical characteristics ofmature adipocytes such as hormonerespons... | Colon_Cancer |
n6methyladenosine m6a regulators are involved in the progression of various cancers via regulating m6amodiï¬cation however the potential role and mechanism of the m6a modiï¬cation in osteosarcoma remains obscurein this study wtap was found to be highly expressed in osteosarcoma tissue and it was an independent progno... | Colon_Cancer |
purpose to explore a new therapeutic option for patients with hepatocellular carcinoma hcc the efficacy and safety of a group of traditional chinese medicines banxia xiexin recipe as monotherapy for patients with advanced hcc was studied materials and methods the study included patients with advanced hcc ... | Colon_Cancer |
biochemically interleukin6 belongs to the class of fourhelical cytokines the cytokine can be synthesised and secreted by many cells it acts via a cell surfaceexpressed interleukin6 receptor which is not signalling competent this receptor when complexed with interleukin6 associates with the signalling receptor glycopro... | Colon_Cancer |
" the choice of treatment in patients with metastatic colorectal cancer mcrc is generally influenced by tumour and patient characteristics treatment efficacy and tolerability and quality of life better patient selection might lead to improved outcomesmethods this post hoc exploratory analysis examined the effect of ... | Colon_Cancer |
high throughput methods in biological and biomedical fields acquire alarge number of molecular parameters or omics data by a single experimentcombining these omics data can significantly increase the capability for recoveringfinetuned structures or reducing the effects of experimental and biological noise indataresul... | Colon_Cancer |
cancer is a complex and heterogeneous disease with many possible genetic and environmentalcauses the same treatment for patients of the same cancer type often results in different outcomes in terms ofefficacy and side effects of the treatment thus the molecular characterization of individual cancer patients isincreas... | Colon_Cancer |
" camp responsive element binding protein creb5 is a transcriptional activator in eukaryotic cells that canregulate gene expression previously we found that creb5 was involved in the occurrence and development of colorectalcancer crc using bioinformatics analysis however the biological roles and underlying regulatory... | Colon_Cancer |
microbiota involves communities ofhepatitis is generally known as an ammation of the liver that can be caused by hepaticand nonhepatic viruses can be caused by alcohol can be drug induced and can be caused byautoimmunity gut microbiota composition is known to be associated with disease pathogenesishowever dynamic alte... | Colon_Cancer |
" the empirical dietary index for hyperinsulinemia edih score is a validated foodbased dietary scorethat assesses the ability of wholefood diets to predict plasma cpeptide concentrations although the edih hasbeen extensively applied and found to be predictive of risk of developing major chronic diseases its influence ... | Colon_Cancer |
specialty sectionthis was submitted tomolecular and cellular oncologya section of the frontiers in cell and developmentalbiologyreceived april accepted july published august citationchen w yang j fang h li l andsun j relevance functionof lincror in the pathogenesisof cancerfront cell dev biol 103389fcell20200069... | Colon_Cancer |
" patients with pelvic malignancies often receive radiosensitising chemotherapy with radiotherapy toimprove survival however this is at the expense of increased normal tissue toxicity particularly in elderly patientshere we explore if an alternative lowcost and nontoxic approach can achieve radiosensitisation in mice ... | Colon_Cancer |
the periparturient period is one of the most challenging periods in dairy cows and encompasses the a0wk prior to and a0wk after parturition the nutrient requirements of dairy cows change greatly during this time largely due to the exponential growth of the gravid uterus and fetus followed by the demands of lac... | Colon_Cancer |
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