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id stringlengths 15 19	title stringlengths 4 685	content stringlengths 54 6.04k	contents stringlengths 77 6.1k	PMID int64 21 3.77M
pubmed23n0001_400	[Biosynthesis of flavins and its regulation in the yeast Pichia guilliermondii].	The nature of riboflavin precursors was studied in the yeast Pichia guilliermondii. By means of mutants with blocked GMP-synthetase the purine precursors of riboflavin were shown to belong to guanylic compounds. Accumulation of 2,4,5-triamino-6-oxypyrimidine, 2,5-diamino-6-oxy-4-ribitylaminopyrimidine, 2,6-dioxy-5-amin...	[Biosynthesis of flavins and its regulation in the yeast Pichia guilliermondii]. The nature of riboflavin precursors was studied in the yeast Pichia guilliermondii. By means of mutants with blocked GMP-synthetase the purine precursors of riboflavin were shown to belong to guanylic compounds. Accumulation of 2,4,5-triam...	834
pubmed23n0001_401	[DNases and RNases of Misgurnus fossilis ovocytes].	The pH optima were determined for DNases and RNases of the loach eggs. For DNases they are 5.6 and 7.6 and for RNases - 5.2 and 7.2. It is established that Ca++ activates, and Fe++ has not effect on the activity of acid and alkaline DNases, while Mg++, Mn++ and especially Co++, Zn++, Cd++, Cu++ have an inhibitory effec...	[DNases and RNases of Misgurnus fossilis ovocytes]. The pH optima were determined for DNases and RNases of the loach eggs. For DNases they are 5.6 and 7.6 and for RNases - 5.2 and 7.2. It is established that Ca++ activates, and Fe++ has not effect on the activity of acid and alkaline DNases, while Mg++, Mn++ and especi...	835
pubmed23n0001_402	[Properties of NAD-pyrophosphorylase of the nuclei of liver cells of chickens].	Certain characteristics of chicken liver cells nuclei NAD-pyrophosphorylase (NMN-adenylytranspherase, EC 2.7.7.1) were investigated. It was established that NAD-pyrophosphorylase activity optimum pH is within interval of 7.0-7.5; temperature optimum - 38-39 degrees C; factor Q10 is equal to 2. Enzyme activation energy,...	[Properties of NAD-pyrophosphorylase of the nuclei of liver cells of chickens]. Certain characteristics of chicken liver cells nuclei NAD-pyrophosphorylase (NMN-adenylytranspherase, EC 2.7.7.1) were investigated. It was established that NAD-pyrophosphorylase activity optimum pH is within interval of 7.0-7.5; temperatur...	833
pubmed23n0001_403	[Catecholamines, cholinergic and serotoninergic complexes as criteria of prognosis in acute cranio-cerebral trauma].	In experiments on 30 animals and in observations over the course of acute closed craniocerebral trauma in 24 patients is was found that the course and prognosis of a posttraumatic period were dependent on the functional activity of the sympathoadrenal system and cholin- and serotoninergic processes. Based on the data o...	[Catecholamines, cholinergic and serotoninergic complexes as criteria of prognosis in acute cranio-cerebral trauma]. In experiments on 30 animals and in observations over the course of acute closed craniocerebral trauma in 24 patients is was found that the course and prognosis of a posttraumatic period were dependent o...	839
pubmed23n0001_404	[Incarcerated gallbladder in cholecystitis].	Among 206 examined patients with cholecystitis and similar diseases in 112 (65%) cases, as evidenced by the authors' findings, the gallbladder proved to be non-functioning. Its escape in the biliary system was functional (indirect) or organic (absolute). The main causes of a direct organic escape of the gallbladder are...	[Incarcerated gallbladder in cholecystitis]. Among 206 examined patients with cholecystitis and similar diseases in 112 (65%) cases, as evidenced by the authors' findings, the gallbladder proved to be non-functioning. Its escape in the biliary system was functional (indirect) or organic (absolute). The main causes of a...	840
pubmed23n0001_405	[Determination of optimal conditions for the electron-cytochemical detection of ATPase activity in isolated nuclei].	The optimal conditions are selected for electron-cytochemical detection of the ATPase activity in nuclei of the skeletal muscles of rabbits and nuclei of Vicia faba L. meristem. It is shown that the previous fixation of nuclei in the rabbit skeletal muscle for 10 min in a mixture of the buffer solutions of 4% glutaric ...	[Determination of optimal conditions for the electron-cytochemical detection of ATPase activity in isolated nuclei]. The optimal conditions are selected for electron-cytochemical detection of the ATPase activity in nuclei of the skeletal muscles of rabbits and nuclei of Vicia faba L. meristem. It is shown that the prev...	836
pubmed23n0001_406	[Determination of the proteolytic activity of beef liver by means of natural substrates labed with 125 I].	There is a description of the determination of the enzymatic activity of acid proteinases: the method is based on the use of 125J-labelled natural protein substrates. Labelled albumin 125J, globulin 125J, and insulin 125J were tested for the determination of activities. All the substrates were hydrolyzed with the enzym...	[Determination of the proteolytic activity of beef liver by means of natural substrates labed with 125 I]. There is a description of the determination of the enzymatic activity of acid proteinases: the method is based on the use of 125J-labelled natural protein substrates. Labelled albumin 125J, globulin 125J, and insu...	841
pubmed23n0001_407	Significance of serum pepsinogen and abomasal pH levels in a field infection of O circumcincta in lambs.	Serum pepsinogen estimations from serially bled lambs grazing on pasture from spring to autumn showed correlations with the availability of Ostertagia larvae on pasture, with faecal egg counts of O circumcincta, and with Ostertagia worm counts in similar lambs slaughtered fort-nightly from the same pasture. In the sla...	Significance of serum pepsinogen and abomasal pH levels in a field infection of O circumcincta in lambs. Serum pepsinogen estimations from serially bled lambs grazing on pasture from spring to autumn showed correlations with the availability of Ostertagia larvae on pasture, with faecal egg counts of O circumcincta, an...	842
pubmed23n0001_408	[Cultivation of Trichomonas gallinarum and Trichomonas tenax on a trimed medium].	Studied was the possibility to isolate and culture Tr. gallinarum and Tr. tenax on a medium Trimed, proposed by the authors for the isolation and cultivation of Tr. vaginalis. The growth and development of the two Trichomonas species were followed up at various temperatures -- 38 degrees, 36 degrees, and 32 degrees C, ...	[Cultivation of Trichomonas gallinarum and Trichomonas tenax on a trimed medium]. Studied was the possibility to isolate and culture Tr. gallinarum and Tr. tenax on a medium Trimed, proposed by the authors for the isolation and cultivation of Tr. vaginalis. The growth and development of the two Trichomonas species were...	843
pubmed23n0001_409	Amylase of the thermophilic actinomycete Thermomonospora vulgaris.	alpha-Amylase of the thermophilic actinomycete Thermomonospora vulgaris was partially purified. Maximal enzyme activity was obtained at 60degreeC and pH 6.0. KM value was l.4%. The effect of some metal salts on enzyme activity was studied. Enzyme activity was inhibited by by KCN, EDTA, and iodoacetate. Inhibition by ED...	Amylase of the thermophilic actinomycete Thermomonospora vulgaris. alpha-Amylase of the thermophilic actinomycete Thermomonospora vulgaris was partially purified. Maximal enzyme activity was obtained at 60degreeC and pH 6.0. KM value was l.4%. The effect of some metal salts on enzyme activity was studied. Enzyme activi...	848
pubmed23n0001_410	[The effect of therapeutic gentamycin doses on the enzyme secretion in urine].	8 patients with chronic pyelonephritis were given gentamycin intramuscularly injected in individual dosage during 8-10 days. Here the behaviour of the excretion of protein, alanine aminopeptidase alkaline phosphatase, alpha-glucosidase, gamma-glutamyl transpeptidase and lysozyme with the urine was tested. With the exce...	[The effect of therapeutic gentamycin doses on the enzyme secretion in urine]. 8 patients with chronic pyelonephritis were given gentamycin intramuscularly injected in individual dosage during 8-10 days. Here the behaviour of the excretion of protein, alanine aminopeptidase alkaline phosphatase, alpha-glucosidase, gamm...	856
pubmed23n0001_411	[Alkaline phosphatases in human feces, intestinal mucosa and bile, and the occurrence of 5'-nucleotidase in feces (author's transl)].	Alkaline phosphatase (EC 3.1.3.1) in extracts of human feces resembles alkaline phosphatase in extracts of duodenal mucosa, except for its electrophoretic mobility in starch gel. It is very probable that the normal feces alkaline phosphatase derives from intestinal mucosa. Gall bladder alkaline phosphatase, which is ma...	[Alkaline phosphatases in human feces, intestinal mucosa and bile, and the occurrence of 5'-nucleotidase in feces (author's transl)]. Alkaline phosphatase (EC 3.1.3.1) in extracts of human feces resembles alkaline phosphatase in extracts of duodenal mucosa, except for its electrophoretic mobility in starch gel. It is v...	858
pubmed23n0001_412	Simultaneous determination of 5'-nucleotidase and alkaline phosphatase activities in serum.	A simple method is described for the simultaneous determination of alkaline phosphatase (EC 3.1.3.1) and 5'-nucleotidase (EC 3.1.3.5) in serum. The method is based on the determination of inorganic phosphorus released by the action of the two enzymes on adenosine-5'-monophosphate at pH 9.5 (200 mmol/l tris-buffer) in t...	Simultaneous determination of 5'-nucleotidase and alkaline phosphatase activities in serum. A simple method is described for the simultaneous determination of alkaline phosphatase (EC 3.1.3.1) and 5'-nucleotidase (EC 3.1.3.5) in serum. The method is based on the determination of inorganic phosphorus released by the act...	859
pubmed23n0001_413	Absorption of short and medium chain fatty acids in the jejunum of the rat.	The uptake of the shortest six fatty acids (acetic to octanoic) was studied in vitro, using everted segments of rat jejunum. The marked influence of medium-pH and fatty acid chain-length suggests that non-ionic diffusion through the lipoid membrane is quantitatively the most important way of transport, but ionic diffus...	Absorption of short and medium chain fatty acids in the jejunum of the rat. The uptake of the shortest six fatty acids (acetic to octanoic) was studied in vitro, using everted segments of rat jejunum. The marked influence of medium-pH and fatty acid chain-length suggests that non-ionic diffusion through the lipoid memb...	860
pubmed23n0001_414	Carcinogenic N-nitro-dimethylamine from the reaction of the analgesic amidopyrine and nitrite extracted from foodstuffs.	The reaction of the analgesic amidopyrine (100 mg) with nitrite extracted from cured meats and from spinach in varying degrees of spoilage was studied. Unde physiological conditions the carcinogenic dimethylnitrosamine was formed at milligram levels at nitrite concentrations as low as 4 mg (in 175 ml extracted from 100...	Carcinogenic N-nitro-dimethylamine from the reaction of the analgesic amidopyrine and nitrite extracted from foodstuffs. The reaction of the analgesic amidopyrine (100 mg) with nitrite extracted from cured meats and from spinach in varying degrees of spoilage was studied. Unde physiological conditions the carcinogenic ...	861
pubmed23n0001_415	[A modern quick method for the acidity determination of the gastric juice (pentagastrin test)].	The author describes a very rapid and accurate method of determining the acidity of gastric juice which is based on recent findings. Starting from the electrometrically determined pH value and the volume of the gastric juice, the actual hydrogenion concentration may be read from a table. The laboratory work is consider...	[A modern quick method for the acidity determination of the gastric juice (pentagastrin test)]. The author describes a very rapid and accurate method of determining the acidity of gastric juice which is based on recent findings. Starting from the electrometrically determined pH value and the volume of the gastric juice...	863
pubmed23n0001_416	Histochemical observations on the occurrence of glycolytic and pentose phosphate cycle enzymes in the hepatopancreas and their possible relation to eyestalk factor(s) in the crab Scylla serrata (Forskal).	Histochemical studies were carried out on some of the glycolytic enzymes viz. phosphorylase, aldose, alpha-glycerophosphate dehydrogenase (alpha-GPDH) and lactic dehydrogenase (LDH) and a key enzyme of the pentose phosphatase cycle, glucose-6-phosphate dehydrogenase (G-6-PDH), in the hepatopancreas of Scylla serrata (F...	Histochemical observations on the occurrence of glycolytic and pentose phosphate cycle enzymes in the hepatopancreas and their possible relation to eyestalk factor(s) in the crab Scylla serrata (Forskal). Histochemical studies were carried out on some of the glycolytic enzymes viz. phosphorylase, aldose, alpha-glycerop...	864
pubmed23n0001_417	[Acid-base equilibrium during physiological pregnancy].	Authors applied blood-gas analysis in 30 healthy gravid women on 3,3 occassions making out 90 cases altogether by blood samples taken from the pulp of the finger capillaries. As a control 27 healthy non-gravid women were examined for comparative analysis. In 10 cases between the 16. and 28. week the results of samples ...	[Acid-base equilibrium during physiological pregnancy]. Authors applied blood-gas analysis in 30 healthy gravid women on 3,3 occassions making out 90 cases altogether by blood samples taken from the pulp of the finger capillaries. As a control 27 healthy non-gravid women were examined for comparative analysis. In 10 ca...	872
pubmed23n0001_418	[The cathode bound group antigen of dysentery-provoking escherichieae (author's transl)].	Antigens from disrupted cells of dysentery-provoking and of non-enteropathogenic Escherichieae were submitted to immunoelectrophoresis on cellulose acetate stripes at pH 8.0. Among 6 immune sera produced for this purpose by immunizing rabbits against desintegrated dysentery bacteria, only one contained a precipitine re...	[The cathode bound group antigen of dysentery-provoking escherichieae (author's transl)]. Antigens from disrupted cells of dysentery-provoking and of non-enteropathogenic Escherichieae were submitted to immunoelectrophoresis on cellulose acetate stripes at pH 8.0. Among 6 immune sera produced for this purpose by immuni...	873
pubmed23n0001_419	[Isolation of the individual structural elements of bacteria of the genus Bordetella and a study of their properties. I. The formation of mureinoplasts and true protoplasts from B. pertussis].	B. pertussis suspension was tested by De Voe et al. method (1970) and its modification with the solutions of a definite ionic composition and a lysozyme. The best results were obtained by the following modification elaborated by the authors. The microbes were grown on the casein-carbon agar for 36 hours and were washed...	[Isolation of the individual structural elements of bacteria of the genus Bordetella and a study of their properties. I. The formation of mureinoplasts and true protoplasts from B. pertussis]. B. pertussis suspension was tested by De Voe et al. method (1970) and its modification with the solutions of a definite ionic c...	875
pubmed23n0001_420	[Sympathico-adrenal system activity in a primary immune response].	Experiments were carried out on linear mice immunized with sheep erythrocytes; it was found that the primary immune respose developed against the background of significant changes in the state of the sympathico-adrenal system, whose activity was determined by the dynamics of catecholamines in the blood and in the tissu...	[Sympathico-adrenal system activity in a primary immune response]. Experiments were carried out on linear mice immunized with sheep erythrocytes; it was found that the primary immune respose developed against the background of significant changes in the state of the sympathico-adrenal system, whose activity was determi...	877
pubmed23n0001_421	[Covalent binding of peroxidase to CH- and AH-Sepharose 4 B].	The properties of peroxidase insolubilized by covalent binding to CH- and AH-Sepharose 4 B in the presence of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) are described. CH-Sepharose 4 B bound peroxidase yields an enzyme preparation with a residual specific activity of 60.6%. When bound to AH-Sepharose 4 B, the...	[Covalent binding of peroxidase to CH- and AH-Sepharose 4 B]. The properties of peroxidase insolubilized by covalent binding to CH- and AH-Sepharose 4 B in the presence of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) are described. CH-Sepharose 4 B bound peroxidase yields an enzyme preparation with a residual s...	878
pubmed23n0001_422	Aerobacter aerogenes PRL-R3 urease. Purification and properties.	A method for the preparation of a 150-fold purified and homogenous A. aerogenes urease is reported. The enzyme exhibited two pH optima at pH 7.0 and 7.5 in triethanolamine and phosphate buffer, respectively. The affinity of the enzyme toward its substrate increased with the increase of pH. No effect of the pH was obser...	Aerobacter aerogenes PRL-R3 urease. Purification and properties. A method for the preparation of a 150-fold purified and homogenous A. aerogenes urease is reported. The enzyme exhibited two pH optima at pH 7.0 and 7.5 in triethanolamine and phosphate buffer, respectively. The affinity of the enzyme toward its substrate...	879
pubmed23n0001_423	Further characterization of the association of glyceraldehyde-3-phosphate dehydrogenase with reticulocyte membranes.	1. The behaviour and properties of membrane-bound GAPDH of rabbit reticulocytes were investigated. 2. The bound GAPDH is more resistant to inactivation by KCl than the soluble enzyme (allotopy). 3. The bound enzyme is released by electrolytes. This effect does not only depend on the ionic strength but additionally on t...	Further characterization of the association of glyceraldehyde-3-phosphate dehydrogenase with reticulocyte membranes. 1. The behaviour and properties of membrane-bound GAPDH of rabbit reticulocytes were investigated. 2. The bound GAPDH is more resistant to inactivation by KCl than the soluble enzyme (allotopy). 3. The b...	880
pubmed23n0001_424	[Effect of the vagus nerve on isolated rabbit atria in ganglionic blockade due to hexamethonium].	By quantitative stimulation of the vagus nerves of isolated rabbit atria frequency-response relations were obtained for both the electrotropic effect (reduction of the area of the monophasic action potential) and the inotropic response. An addition of hexamethonium in a final concentration of 10(-5) g/ml resulted in a ...	[Effect of the vagus nerve on isolated rabbit atria in ganglionic blockade due to hexamethonium]. By quantitative stimulation of the vagus nerves of isolated rabbit atria frequency-response relations were obtained for both the electrotropic effect (reduction of the area of the monophasic action potential) and the inotr...	881
pubmed23n0001_425	Chemical relaxation studies on the system liver alcohol dehydrogenase, NADH and imidazole.	Several years ago, Theorell and Czerlinski conducted experiments on the system of horse liver alcohol dehydrogenase, reduced nicotinamide adenine dinucleotide and imidazole, using the first version of the temperature jump apparatus with detection of changes in fluorescence. These early experiments were repeated with im...	Chemical relaxation studies on the system liver alcohol dehydrogenase, NADH and imidazole. Several years ago, Theorell and Czerlinski conducted experiments on the system of horse liver alcohol dehydrogenase, reduced nicotinamide adenine dinucleotide and imidazole, using the first version of the temperature jump apparat...	882
pubmed23n0001_426	Comparative study of virological infections in asthmatic and nonasthmatic children.	The author shows complex analyses: clinical, laboratory, X-rays, bronchoscopical, bronchographical and measuring lung function tests as well as the serological examinations in blood serum of both groups of asthmatic and nonasthmatic children with virological infection. The calculation of statistically significant diffe...	Comparative study of virological infections in asthmatic and nonasthmatic children. The author shows complex analyses: clinical, laboratory, X-rays, bronchoscopical, bronchographical and measuring lung function tests as well as the serological examinations in blood serum of both groups of asthmatic and nonasthmatic chi...	884
pubmed23n0001_427	Multiple forms of staphylococcal alpha-toxin.	A group of proteins was readily extracted at neutrality from trichloroacetic acid precipitates of staphylococcal culture filtrate supernatants, while alpha-toxin was dissolved and activated by treating the precipitate with 8 M urea, with acidic buffers or by heating to 90-100 degrees C at neutrality. Heat activation of...	Multiple forms of staphylococcal alpha-toxin. A group of proteins was readily extracted at neutrality from trichloroacetic acid precipitates of staphylococcal culture filtrate supernatants, while alpha-toxin was dissolved and activated by treating the precipitate with 8 M urea, with acidic buffers or by heating to 90-1...	886
pubmed23n0001_428	Acute otitis media. A clinical bacteriological and serological study of children with frequent episodes of acute otitis media.	A series of episodes of acute otitis media was studied with reference to bacterial findings and specific serological responses in 48 children with histories of frequent episodes before. D. pneumoniae and H. influenzae were the most frequently isolated pathogens. Re-isolations after therapy were often made in episodes w...	Acute otitis media. A clinical bacteriological and serological study of children with frequent episodes of acute otitis media. A series of episodes of acute otitis media was studied with reference to bacterial findings and specific serological responses in 48 children with histories of frequent episodes before. D. pneu...	885
pubmed23n0001_429	Endosymbiosis and cellular tolerance in the Hawaiian soft coral Sarcothelia edmondsoni verrill.	The relationship between the soft coral Sarcothelia edmondsoni Verrill and its symbiotic algae is considered as an early instance of cellular tolerance which can be disturbed by a variety of adverse conditions. The algal cells lie in vesicles deep within the endodermal cells of the host and are not subject to digestion...	Endosymbiosis and cellular tolerance in the Hawaiian soft coral Sarcothelia edmondsoni verrill. The relationship between the soft coral Sarcothelia edmondsoni Verrill and its symbiotic algae is considered as an early instance of cellular tolerance which can be disturbed by a variety of adverse conditions. The algal cel...	899
pubmed23n0001_430	Epidemiologic investigations of the 1969 epidemic of Venezuelan encephalitis in Ecuador.	An epizoodemic of Venezuelan equine encephalitis (VEE), subtype I variant B, occurred in Ecuador during the rainy and hot season of 1969. In this paper, a general description of the epidemic is given and virus isolations from humans are reported. A serologic survey was performed in order to determine the extension of t...	Epidemiologic investigations of the 1969 epidemic of Venezuelan encephalitis in Ecuador. An epizoodemic of Venezuelan equine encephalitis (VEE), subtype I variant B, occurred in Ecuador during the rainy and hot season of 1969. In this paper, a general description of the epidemic is given and virus isolations from human...	906
pubmed23n0001_431	Congenital malformations of the central nervous system produced by narcotic analgesics in the hamster.	Maternal dose--fetal teratogenic response data were obtained for a variety of narcotic and related compounds by single subcutaneous injections of the drugs into pregnant hamsters during the critical periods of central nervous system organogenesis. The number of abnormal fetuses from females injected with diacetylmorphi...	Congenital malformations of the central nervous system produced by narcotic analgesics in the hamster. Maternal dose--fetal teratogenic response data were obtained for a variety of narcotic and related compounds by single subcutaneous injections of the drugs into pregnant hamsters during the critical periods of central...	907
pubmed23n0001_432	Evaluation of a non-professional visual screening method.	A screening method designed for administration by lay personnel is evaluated and compared to Modified Clinical Technique screening results for a screening of 1600 elementary school children.	Evaluation of a non-professional visual screening method. A screening method designed for administration by lay personnel is evaluated and compared to Modified Clinical Technique screening results for a screening of 1600 elementary school children.	908
pubmed23n0001_433	Ionic requirements of proximal tubular sodium transport. II. Hydrogen ion.	Simultaneous perfusion to proximal convoluted tubules and peritubular capillaries was used to study the effects of different perfusion fluids on sodium reabsorption and hydrogen secretion, which was calculated as bicarbonate reabsorption and titratable acid. Results show that sodium reabsorption was not tightly coupled...	Ionic requirements of proximal tubular sodium transport. II. Hydrogen ion. Simultaneous perfusion to proximal convoluted tubules and peritubular capillaries was used to study the effects of different perfusion fluids on sodium reabsorption and hydrogen secretion, which was calculated as bicarbonate reabsorption and tit...	909
pubmed23n0001_434	ECS, intracellular pH, and electrolytes of cardiac and skeletal muscle.	The extracellular space (ECS) of muscle from each ventricle of the heart (RV and LV), the atria, diaphragm, and quadriceps was estimated in the anesthetized rabbit from the distribution volumes of [14C]insulin, [14C]sucrose, [51Cr]EDTA, and C1--. Whole-tissue electrolytes were measured and intracellular electrolytes ca...	ECS, intracellular pH, and electrolytes of cardiac and skeletal muscle. The extracellular space (ECS) of muscle from each ventricle of the heart (RV and LV), the atria, diaphragm, and quadriceps was estimated in the anesthetized rabbit from the distribution volumes of [14C]insulin, [14C]sucrose, [51Cr]EDTA, and C1--. W...	910
pubmed23n0001_435	Intracellular pH and K+ of cardiac and skeletal muscle in acidosis and alkalosis.	The effects of a metabolic and respiratory acidosis and alkalosis on intracellular pH (pHi) and K+ have been compared in cardiac and skeletal muscle from the anesthetized rabbit. The extracellular space and pHi were calculated from the distribution volumes of [51Cr] EDTA and [14C]DMO, respectively. When pHe was varied ...	Intracellular pH and K+ of cardiac and skeletal muscle in acidosis and alkalosis. The effects of a metabolic and respiratory acidosis and alkalosis on intracellular pH (pHi) and K+ have been compared in cardiac and skeletal muscle from the anesthetized rabbit. The extracellular space and pHi were calculated from the di...	911
pubmed23n0001_436	Effects of autonomic neurohumors on transmembrane potentials of atrial plateau fibers.	Isolated canine atrial plateau fibers were treated with acetylcholine or norepinephrine to note the effects on the transmembrane potential. Acetylcholine, 1.0 or 2.0 mug/ml, consistently reduced the slope of inherent phase 4 depolarization. Increases in maximum diastolic potential and rising velocity occurred along wit...	Effects of autonomic neurohumors on transmembrane potentials of atrial plateau fibers. Isolated canine atrial plateau fibers were treated with acetylcholine or norepinephrine to note the effects on the transmembrane potential. Acetylcholine, 1.0 or 2.0 mug/ml, consistently reduced the slope of inherent phase 4 depolari...	912
pubmed23n0001_437	Interstitial fluid pressure and alkaline gastric secretion.	The interstitial fluid pressure of the submucosa of the gastric fundus was monitored by means of Guyton's capsules in dogs anesthetized with pentobarbital. The intracapsular pressure (ICP) was measured during secretion produced by: a) hypertonic solutions placed inside the stomach; b) arterial hypertension (200 mmHg) a...	Interstitial fluid pressure and alkaline gastric secretion. The interstitial fluid pressure of the submucosa of the gastric fundus was monitored by means of Guyton's capsules in dogs anesthetized with pentobarbital. The intracapsular pressure (ICP) was measured during secretion produced by: a) hypertonic solutions plac...	913
pubmed23n0001_438	Overview: maintenance therapy in psychiatry: I. Schizophrenia.	Hospital psychiatry has evolved from long-term "treatment" programs that were primarily custodial to the successful pharmacological treatment of acute psychotic episodes. Unfortunately, many patients still return to the hospital with relapses. This so-called revolving door syndrome draws attention to the critical impor...	Overview: maintenance therapy in psychiatry: I. Schizophrenia. Hospital psychiatry has evolved from long-term "treatment" programs that were primarily custodial to the successful pharmacological treatment of acute psychotic episodes. Unfortunately, many patients still return to the hospital with relapses. This so-calle...	914
pubmed23n0001_439	Inpatient and outpatient patterns of psychotropic drug prescribing by nonpsychiatrist physicians.	The authors found that among 228 general hospital patients, minor tranquilizers were prescribed most often and with the least justification and that major tranquilizers were prescribed sparingly and by and large judiciously. Antidepressants were given less often than would be justified by the incidence of depressive il...	Inpatient and outpatient patterns of psychotropic drug prescribing by nonpsychiatrist physicians. The authors found that among 228 general hospital patients, minor tranquilizers were prescribed most often and with the least justification and that major tranquilizers were prescribed sparingly and by and large judiciousl...	915