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Effect of Bay U 3405, a new thromboxane antagonist, on collagen-induced thromboembolism in rabbits. Bay U 3405 [(3R)-3-(4-fluorophenylsulfonamido)-1,2,3,4-tetrahydro-9- carbazolepropanoic acid] potently inhibits platelet aggregation, thromboxane A2-induced contraction of smooth muscles, and coronary artery thrombosis. ... | cardiovascular diseases |
Conservative therapy for adnexal torsion. A case report. Adnexal torsion has traditionally been treated with oophorectomy because of the fear that untwisting the ovarian pedicle may result in a thrombotic embolus. Such a patient had bilateral adnexal torsion secondary to dermoid cysts. Since standard therapy, oophorect... | cardiovascular diseases |
The daylong pattern of the antianginal effect of long-term three times daily administered isosorbide dinitrate Three times daily administration of isosorbide dinitrate may avoid much of the tolerance seen with more frequent dosing. To determine the daylong pattern of the antianginal effect of three times daily isosorbi... | cardiovascular diseases |
Melanoma in pregnancy. The clinical course of malignant melanoma in pregnancy has been a subject of controversy, but current evidence indicates that it is similar to the clinical course in non-pregnant patients. Early detection and biopsy of localized disease is crucial because early treatment provides an excellent pro... | neoplasms |
Overt hepatic encephalopathy precipitated by zinc deficiency. Encephalopathy in liver disease may be unresponsive to protein restriction, lactulose, and neomycin. Zinc supplements have been reported to improve psychometric performance in liver cirrhosis, but the importance of zinc deficiency in overt hepatic encephalop... | general pathological conditions |
Effect of lovastatin on intimal hyperplasia after balloon angioplasty: a study in an atherosclerotic hypercholesterolemic rabbit. Restenosis, the major limitation of balloon angioplasty, is the result of intimal hyperplasia after the procedure. Lovastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) inhibitor, ma... | cardiovascular diseases |
The rapid detection of clonal T-cell proliferations in patients with lymphoid disorders. A series of T-cell proliferations in peripheral blood, bone marrow, or tissue samples were analyzed for clonality. The technique used employs the polymerase chain reaction to amplify portions of the rearranged T-cell receptor beta ... | neoplasms |
Paraneoplastic brachial plexopathy in a patient with Hodgkin's disease. We describe a case of inflammatory brachial plexopathy that occurred in the context of a mild, diffuse sensorimotor peripheral neuropathy associated with Hodgkin's disease. Clinical, electrophysiologic, and pathologic studies helped distinguish thi... | neoplasms |
Motor units in incomplete spinal cord injury: electrical activity, contractile properties and the effects of biofeedback. The electrical and contractile properties of hand muscles in a selected population of quadriplegic subjects were studied intensively before and after EMG biofeedback. Spontaneously active motor unit... | nervous system diseases |
Gastroesophageal reflux and sclerotherapy strictures. The development of esophageal stricture is common following endoscopic variceal sclerotherapy (EVS). Gastroesophageal reflux may be at least partly responsible. Twelve randomly selected male patients underwent chronic EVS for the management of bleeding esophageal va... | general pathological conditions |
Rhabdomyosarcoma. From the laboratory to the clinic. The prospect of identifying and developing new agents for treatment of rhabdomyosarcomas is discussed in the light of current prognosis for children with advanced stage disease. Preliminary attempts to identify tumor-specific agents using in vitro cell culture show p... | neoplasms |
Modulation of the stretch reflex during volitional sinusoidal tracking in Parkinson's disease. Sinusoidal visually-guided wrist tracking, in normal and parkinsonian subjects, was perturbed by torque transients every 90 degrees throughout the movement. Long-latency stretch reflex and volitional EMG amplitude modulations... | nervous system diseases |
Plasma thrombin-antithrombin III complexes in the diagnosis of primary hepatocellular carcinoma complicating liver cirrhosis. Detection of hypercoagulable state might be helpful in the diagnosis of primary hepatocellular carcinoma (HCC) complicating liver cirrhosis (LC). Plasma levels of thrombin-antithrombin III compl... | digestive system diseases |
Early scintigraphic detection of experimental myocardial infarction in dogs with technetium-99m-glucaric acid Recent data have generated some interest in technetium-99m-(99mTc) glucaric acid as an in vivo viability marker. We studied 99mTc-glucaric acid retention in canine models of myocardial ischemia (20-min occlusio... | cardiovascular diseases |
Is gastric acid responsible for the pain in patients with essential dyspepsia? The pathogenesis of symptoms in patients with essential dyspepsia is not known. Since treatment with H2-receptor antagonists has provided symptomatic relief in some reports, we carried out the present study to investigate whether gastric aci... | nervous system diseases |
Late recurrence of a hepatocellular carcinoma in a patient with incomplete Alagille syndrome. In this study, the case of a patient presenting a second hepatocellular carcinoma 13 years after resection of a first tumor of the same type is reported. In this case, etiological investigations remained negative, but an incom... | general pathological conditions |
Hospital management of voluntary total fasting among political prisoners In 1989 20 political detainees, held without trial for up to 32 months, were admitted, on hunger strike, to the Johannesburg Hospital, South Africa. Most were held under the regulations of the State of Emergency (since revoked) and 5 were held inc... | general pathological conditions |
Cancer mortality in workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin BACKGROUND. In both animal and epidemiologic studies, exposure to dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin, or TCDD) has been associated with an increased risk of cancer. METHODS. We conducted a retrospective cohort study of mortality among t... | neoplasms |
An inconsistent relationship between insulin and blood pressure in three Pacific island populations. The evidence linking insulin to blood pressure is controversial, and results for groups similarly categorized by body mass, glucose tolerance and hypertensive status are often contradictory. We have investigated the rel... | cardiovascular diseases |
Significance of magnetic resonance imaging in acute head injury. One hundred seventy-seven patients who had incurred head trauma were studied with magnetic resonance imaging (MRI). Patients varied from those with mild injury without any focal neurological deficit to those with severe injury with post-traumatic coma. Al... | general pathological conditions |
Similar time course of ST depression during and after exercise in patients with coronary artery disease and syndrome X. To assess whether the time course of ST segment depression differs in patients with coronary artery disease and patients with angina and normal coronary arteries, the exercise tests of 54 patients wit... | general pathological conditions |
Late development of a squamous carcinoma in a reconstructed pharynx. We report a case in which a squamous cell carcinoma was found to have arisen from a delto-pectoral skin flap used in pharyngeal reconstruction. The flap had been forming a neo-pharynx for 24 years. No other signs of recurrent disease had developed in ... | neoplasms |
Estrogen replacement and coronary artery disease. Effect on survival in postmenopausal women. The relationship among postmenopausal estrogen use, coronary stenosis, and survival was examined retrospectively in 2268 women undergoing coronary angiography. The patients were selected for study if their age was 55 years or ... | cardiovascular diseases |
Gallstone dissolution. Many methods are available for gallstone dissolution, including oral bile salts; cholesterol solvents such as mono-octanoin or methyl tert-butyl either; and calcium or pigment solvents such as EDTA and polysorbate. Which of these approaches will be appropriate for an individual patient depends on... | digestive system diseases |
Two-year outcome after angiographically documented myocardial reperfusion for acute coronary occlusion. Thrombolysis and Angioplasty Study Group. Reperfusion therapy has been clearly shown to decrease the early mortality after acute myocardial infarction, but the impact of this therapy on long-term survival has been le... | cardiovascular diseases |
Reconstruction of patellar tendon rupture after total knee arthroplasty with an extensor mechanism allograft. Although patellar tendon rupture after total knee arthroplasty (TKA) is a rare complication, the consistently poor outcome of conventional tendon repair has convinced some to abandon such reconstruction in favo... | general pathological conditions |
Computed tomographic and ultrasonographic findings in women with acute fatty liver of pregnancy. Acute fatty liver of pregnancy is associated with complications that can influence antepartum management and necessitate delivery. To date, liver biopsy has been regarded as the "gold standard" for diagnosis. Radiologic eva... | digestive system diseases |
Prognostic factors in primary retroperitoneal soft-tissue sarcomas. We analyzed independent treatment variables (age, sex, signs and symptoms, site, size, histopathologic findings, grade, and clinical presentation) and treatment-dependent variables (resectability, type of operation, surgical margins, surgical boundarie... | neoplasms |
Left superior vena cava: a pitfall in computed tomographic diagnosis with surgical implications. We report 2 cases in which computed tomography of the mediastinum demonstrated an abnormality originally misinterpreted as lymphadenopathy but subsequently shown to represent a left superior vena cava. Misinterpretation may... | neoplasms |
Long-term follow-up of patients operated on for recurrent carotid stenosis. We reviewed our experience with 29 operations for recurrent carotid stenosis in 27 patients who underwent both their primary carotid endarterectomy and their reoperations at our institution. These 27 patients represent 4% of the 667 patients wh... | nervous system diseases |
Tumor-targeted chemotherapy with lipid contrast medium and macromolecular anticancer drug (SMANCS) for renal cell carcinoma. Twenty-five patients with renal cell carcinoma were treated with a lipophilic macromolecular drug, poly(stylene-co-maleic acid)-conjugated neocarzinostatin (SMANCS) dissolved in lipid contrast me... | neoplasms |
Increased epidermal growth factor receptors in seborrheic keratoses and acrochordons of patients with the dysplastic nevus syndrome. Seborrheic keratoses and acrochordons may change in biologic behavior with pregnancy or during treatment with sex steroids. Because epidermal growth factor receptor localization may chang... | neoplasms |
A patient-oriented approach to perilymph fistula. The subject of perilymph fistula is controversial in part because the preoperative diagnosis of perilymph fistula is difficult. Patients suffering auditory and vestibular symptoms secondary to perilymph fistula, therefore, present a dilemma to the practicing physician. ... | general pathological conditions |
Hereditary internal anal sphincter myopathy causing proctalgia fugax and constipation. A newly identified condition. A newly identified myopathy of the internal anal sphincter is described. In the affected family, at least one member from each of five generations had severe proctalgia fugax; onset was usually in the th... | digestive system diseases |
Itraconazole in opportunistic mycoses: cryptococcosis and aspergillosis. Striking results were obtained with oral itraconazole therapy in two opportunistic mycoses. Of 28 patients with cryptococcal meningitis, 18 achieved complete responses, including 16 of 24 patients with acquired immunodeficiency syndrome. Other man... | general pathological conditions |
Detection of HTLV-I proviral sequences in CD30-positive large cell cutaneous T-cell lymphomas. To investigate the possibility that cutaneous T-cell lymphomas of large cell type may be associated with human T-cell leukemia/lymphoma virus type I infection in nonendemic regions, tissue samples from six cases of large cell... | neoplasms |
The early diagnosis and treatment of developmental patella infera syndrome. Developmental patella infera and associated arthrofibrosis after knee surgery require prompt recognition and treatment. The condition develops because of contracture of peripatellar tissues, fatpad tissues, and quadriceps weakness, and may rapi... | general pathological conditions |
Multifocal colitis associated with an epidemic of chronic diarrhea. An outbreak of a chronic diarrheal syndrome was detected between May and August 1987 in rural Henderson County, Illinois. Seventy-two individuals were affected. Epidemiological studies performed by the Center for Disease Control implicated the water of... | digestive system diseases |
Intestinal obstruction by distension of a Foley jejunostomy catheter. Jejunostomies can be effective in permitting postoperative nutritional support, particularly in the patient with complicated gastrointestinal disease. In the case presented, however, distension of the Foley balloon catheter, used as the jejunostomy t... | digestive system diseases |
Mechanical ventilation in medical and neurological diseases: 11 years of experience. Mechanical ventilation (MV) is imperative in many forms of acute respiratory failure (ARF). The aim of this work was to review all episodes of MV in a Medical Intensive Care Unit (MICU) during the 11-year period 1976-1986. Four per cen... | neoplasms |
Relationship of parental smoking to wheezing and nonwheezing lower respiratory tract illnesses in infancy. Group Health Medical Associates. The relationship between parental smoking and lower respiratory tract illness (LRI) was studied in a large cohort of infants followed prospectively from birth. Illnesses were diagn... | general pathological conditions |
Sustained calcium channel blockade in the treatment of severe hypertension. A two year experience. Thirty-nine patients with severe hypertension (diastolic blood pressure greater than 120 mm Hg) predominantly drawn from an inner-city population were placed on nifedipine gastrointestinal therapeutic system (GITS) for lo... | cardiovascular diseases |
The epidemiology of ophthalmic malignancies in New York State. The epidemiologic characteristics of more than 1400 primary eye cancers (ICD-9, site 190) diagnosed among New York State (NYS) residents between 1975 and 1986 are described. Among NYS male residents, the average annual age-adjusted incidence rate was 7.5 pe... | neoplasms |
Nonbacterial thrombotic endocarditis in Hong Kong Chinese. Fifty-two Hong Kong Chinese cases of nonbacterial thrombotic endocarditis at autopsy were reviewed to ascertain if there was any difference in autopsy incidence, associated diseases, age and sex incidence, distribution of infarcts, and pattern of valve involvem... | cardiovascular diseases |
High or low hepaticojejunostomy for bile duct strictures? The 19 patients who underwent 22 postoperative repairs of bile duct stricture in our institution between 1973 and 1984 were evaluated to assess whether the recognition of the tenuous blood supply of the supraduodenal bile duct in 1979 had improved the results th... | general pathological conditions |
Relationships of somatic symptoms to behavioral and emotional risk in young adolescents. Junior high students (n = 1508) from a midwestern community completed a health behavioral questionnaire that asked the frequency of headache and abdominal pain and of a number of behavioral and emotional risk indicators. Headache (... | digestive system diseases |
Enterogenous cyst of the cerebellopontine angle cistern: case report. A case of an enterogenous cyst located in the cerebellopontine angle cistern is presented. These cysts have usually been found in the spinal canal, and their intracranial occurrence is exceptional. In the present case, the cyst was lined histological... | nervous system diseases |
Nimodipine after resuscitation from out-of-hospital ventricular fibrillation. A placebo-controlled, double-blind, randomized trial. One hundred fifty-five consecutive patients resuscitated after out-of-hospital ventricular fibrillation by a physician-manned advanced life support unit were randomly assigned to receive n... | general pathological conditions |
The prevalence of Helicobacter pylori infection in the Peoples Republic of China. Meta-analysis on data from 16 (two volunteer and 14 endoscopic) studies ahs been performed to investigate the prevalence of Helicobacter pylori infection in the stomachs of individuals within the Peoples Republic of China. In this survey ... | neoplasms |
Primary repair for complete atrioventricular canal: recommendation for early primary repair. Forty patients with complete atrioventricular canal (CAVC) underwent primary repair at Fukuoka Children's Hospital in Fukuoka, Japan, between August 1, 1981 and July 31, 1989. The age at repair ranged from 2 months to 6 years (... | cardiovascular diseases |
Potential value of hormone receptor assay in carcinoma in situ of breast. The estrogen receptor (ER) expression of invasive breast cancer has been extensively studied both biochemically and with specific monoclonal antibodies against ER. Relatively few studies have attempted to characterize ER pattern in breast carcino... | general pathological conditions |
Monocortical miniplate fixation of mandibular angle fractures. Noncompression monocortical miniplate fixation of mandibular fractures has become a reliable method of providing rigid fixation and eliminating the need for intermaxillary fixation. Recent studies, using a variety of internal fixation techniques, have descr... | general pathological conditions |
Expandable biliary metal stents for malignancies: endoscopic insertion and diathermic cleaning for tumor ingrowth. Seventeen patients with malignant biliary strictures have been treated by endoscopic insertion of self-expandable metallic prostheses. Two patients received two prostheses inserted simultaneously in both t... | digestive system diseases |
Changes in left ventricular volume, mass, and function during the development and regression of supraventricular tachycardia-induced cardiomyopathy. Disparity between recovery of systolic versus diastolic function. Chronic supraventricular tachycardia causes a dilated cardiomyopathy in man. Terminating this tachycardia... | cardiovascular diseases |
Experimental studies of the physiologic properties of technetium-99m isonitriles. Recently, efforts have been directed at the development of technetium-99m (Tc-99m)-labeled isonitrile compounds for assessment of regional perfusion and viability after experimental myocardial infarction or ischemia. One of the most promi... | cardiovascular diseases |
Fourth ventricular schwannoma. Case report. A schwannoma arising from the dorsum of the pontomedullary junction and presenting as an exophytic mass in the fourth ventricle is described. A ventricular schwannoma has not previously been reported in the literature. The presenting clinical and radiographic features and the... | neoplasms |
Lymphokine-activated killer (LAK) cell activity in B and T chronic lymphoid leukemia: defective LAK generation and reduced susceptibility of the leukemic cells to allogeneic and autologous LAK effectors. The capacity to generate lymphokine-activated killer (LAK) cells and the susceptibility of the neoplastic cells to b... | neoplasms |
Mini-perforation of the colon--not all postpolypectomy perforations require laparotomy. In a 10-year experience with 4,784 consecutive colonoscopic polypectomies, the need for operative intervention in just two of seven perforations indicates that patients with specially defined, limited perforations can usually be tre... | digestive system diseases |
Effect of vaginal delivery on the pelvic floor: a 5-year follow-up. We have studied the pelvic floor musculature and its innervation in 14 of 24 (58 per cent) multiparous women who had been recruited into a study of the effect of childbirth on the pelvic floor as part of a prospective investigation that began in 1983. ... | nervous system diseases |
Speech, velopharyngeal function, and hearing before and after orthognathic surgery. Articulation, voice, resonance, hearing sensitivity, and middle ear function were examined in 34 patients before and 3, 6, 9, and 12 months after orthognathic surgery. Thirty of the 34 patients had articulation errors before surgery. Er... | general pathological conditions |
Grafting of venous leg ulcers. An intraindividual comparison between cultured skin equivalents and full-thickness skin punch grafts. Skin equivalents that consisted of a noncontracted collagen gel populated with allogeneic fibroblasts and covered with autologous cultured keratinocytes were used for grafting venous leg ... | general pathological conditions |
Sarcosaprophagous fly activity in Maryland. Eighty-six successful rearings of sarcosaprophagous flies characteristic of the first successional insect wave of infestation of a corpse were conducted under field conditions in Maryland. Different species were observed to be active during spring and summer. The development ... | general pathological conditions |
Combined laminoplasty and posterolateral fusion for spinal canal surgery in children and adolescents. Spinal deformities, especially kyphosis and instability, after laminectomy for tumors and other diseases, are major clinical problems. Since 1981, combined laminoplasty and posterolateral fusion for the prevention of p... | neoplasms |
Maternal feeding behavior and child acceptance of food during diarrhea, convalescence, and health in the central Sierra of Peru. Feeding patterns by mothers and child acceptance of food were measured in a Peruvian village to determine changes on days when children had diarrhea as compared to days of convalescence and h... | general pathological conditions |
Surgical management of islet cell dysmaturation syndrome in young children. Islet cell dysmaturation syndrome (ICDS) encompasses the causes of infantile hyperinsulinemic hypoglycemia histologically described as islet cell hyperplasia, pancreatic adenomatosis and nesidioblastosis. Eleven infants underwent 14 pancreatic ... | general pathological conditions |
Severe hypertension after liver transplantation in alpha 1 antitrypsin deficiency. Five children with alpha 1 antitrypsin deficiency and terminal liver disease received liver grafts; all five became hypertensive and four developed hypertensive encephalopathy. There was evidence of renal disease preoperatively and renal... | digestive system diseases |
Neurobehavioral outcome 1 year after severe head injury. Experience of the Traumatic Coma Data Bank. The outcome 1 year after they had sustained a severe head injury was investigated in patients who were admitted to the neurosurgery service at one of four centers participating in the Traumatic Coma Data Bank (TCDB). Of... | nervous system diseases |
Obesity and colorectal adenomatous polyps. Obesity has been investigated as a risk factor for various malignancies, including colon cancer. A case-control study was conducted on patients in three colonoscopy practices in New York City to determine possible risk factors for colorectal adenomatous polyps, a known precurs... | neoplasms |
Surgery for thoracoabdominal aortic aneurysms. From July 1985 to July 1989, Loma Linda University Medical Center evaluated 46 thoracoabdominal aortic aneurysms (TAAAs). Forty patients were taken to surgery--18 (45%) were operated on an emergency basis for reasons including rupture (12 patients, 30%), dissection (5 pati... | cardiovascular diseases |
Clinical significance of plasminogen activator inhibitor activity in patients with exercise-induced ischemia. To assess the fibrinolytic system in patients with exercise-induced ischemia and its relation to ischemia and severity of coronary artery disease (CAD), 47 patients with CAD confirmed by results of coronary ang... | cardiovascular diseases |
Dietary calcium, vascular reactivity, and genetic hypertension in the Lyon rat strain. In order to examine the relationship existing between dietary calcium and the development of hypertension, we developed a long-term study in the Lyon hypertensive rat strain (LH) and two control strains, the Lyon normotensive (LN) an... | cardiovascular diseases |
Landau-Kleffner syndrome: a pharmacologic study of five cases. Five children with Landau-Kleffner syndrome (epilepsy, acquired aphasia, and continuous spike-wave discharges during sleep), were treated with antiepileptic drugs (AEDs), sleep-modifying drugs, and corticosteroids. The pharmacologic profiles differed from t... | nervous system diseases |
Endometrial ablation for the treatment of menorrhagia: a comparison of patients with normal, enlarged, and fibroid uteri. One hundred sixty-one patients underwent endometrial ablation with the Nd:YAG laser for the treatment of refractory menorrhagia. Patients were divided into one of three groups: those with a normal-s... | neoplasms |
The normal mediastinum in blunt traumatic rupture of the thoracic aorta and brachiocephalic arteries. In a review of 52 articles, published between 1953 and 1989, 656 patients with blunt traumatic rupture of the thoracic aorta or brachiocephalic arteries were identified. Of these, 608 (92.7%) had an abnormal mediastinu... | cardiovascular diseases |
Enhanced modulation of antibodies coating guinea pig leukemic cells in vitro and in vivo. The role of Fc gamma R expressing cells. We have investigated the antigenic modulation induced by a number of antibody fragments and derivatives directed against the idiotype of the surface Ig of the L2C guinea pig B lymphoblastic... | neoplasms |
Use of quinapril in the elderly patient. Quinapril hydrochloride is a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor that has been extensively tested and found effective when administered once-a-day to hypertensive patients of both sexes and all degrees of hypertension and cardiac compromise, including tho... | cardiovascular diseases |
Diagnostic imaging and surgical treatment of dumbbell tumors of the mediastinum. We describe the diagnostic procedures and surgical approaches employed in 5 patients with dumbbell tumors of the mediastinum. Magnetic resonance imaging accurately described the existence and longitudinal extension of the intraspinal compo... | neoplasms |
Aortocaval and iliac arteriovenous fistulas: recognition and treatment. Despite the well characterized physiologic effects of aortocaval or iliac arteriovenous fistulas, patients with such uncommon lesions may manifest a diverse array of symptoms, and diagnosis is often delayed or overlooked. To examine clinical featur... | general pathological conditions |
The acutely affected abdomen in paraplegic spinal cord injury patients. The records of 145 paraplegic or quadriplegic patients were reviewed to identify those factors useful in the correct diagnosis of the acute abdomen in this population. Twenty-one patients had 22 episodes of acute or subacute abdominal problems. Pre... | digestive system diseases |
Extraperitoneal endarterectomy for iliofemoral occlusive disease. Sixty patients with iliofemoral occlusive disease were treated by autogenous anatomic reconstruction by endarterectomy. Endarterectomy was performed extra-peritoneally by the eversion technique. The operative technique and its advantages and disadvantage... | general pathological conditions |
Health effects of radon exposure. Report of the Council on Scientific Affairs, American Medical Association. The consensus of scientists is that exposure to radon is hazardous, but disagreement exists about the effects of lower radon concentrations. Studies of underground miners have indicated that the risk of lung can... | neoplasms |
Traumatic popliteal artery pseudoaneurysms: case report and review of the literature. Traumatic pseudoaneurysms of the popliteal artery are an uncommon late complication of arterial injury. Although reviewed extensively in wartime, they occur less frequently in civilian trauma and have accordingly been less frequently ... | cardiovascular diseases |
Genetic determination of cytomegalovirus-induced and age-related cardiopathy in inbred mice. Characterization of infiltrating cells. Carditis developed 7 days after the administration of murine cytomegalovirus to neonatal, young adult or aged mice of varying sensitivity to lethal infection with this virus. The inflamma... | cardiovascular diseases |
Intraoperative ultrasonic imaging of the ascending aorta in ischemic heart disease. In an attempt to locate any atherosclerotic lesion in the ascending aorta and to prevent embolization, intraoperative B-mode ultrasonography was performed in 100 patients with ischemic heart disease (31 women and 69 men). Ultrasonograph... | cardiovascular diseases |
Power of oesophageal peristalsis can be controlled voluntarily. The hypothesis that oesophageal peristalsis can be modified voluntarily was explored. Six healthy male volunteers and eight female patients with angina like chest pain underwent oesophageal manometry. Each was asked to take a series of swallows, and to var... | cardiovascular diseases |
Long-term effect of mexiletine on left ventricular function and relation to suppression of ventricular arrhythmia. The effects of oral mexiletine on left ventricular (LV) ejection fraction (EF) and ventricular arrhythmias--and a possible relation between these effects--were evaluated during 3 months of therapy in 29 pa... | cardiovascular diseases |
Carcinoma of the vulva. Clinicopathologic factors involved in inguinal and pelvic lymph node metastasis. Eighty-five women with vulvar squamous cell carcinoma were subjected to radical vulvectomy with bilateral inguinal and femoral node dissection or to radical vulvectomy with bilateral inguinofemoral and deep pelvic n... | neoplasms |
Continuing care for cancer pain relief with oral morphine solution. One-year experience in a regional cancer center. This report is a prospective study of 223 patients with intractable cancer pain who were offered continuing care during the year 1988 at the Pain Relief Unit, Kidwai Memorial Institute of Oncology, Banga... | neoplasms |
Aortobronchial fistula after an aortic operation. A 71-year-old man with a postoperative aortobronchial fistula was successfully treated. The fistula occurred between the left lower lobe and the descending thoracic aorta, to which a distal anastomosis of a temporary bypass graft had been placed during thoracic aortic a... | cardiovascular diseases |
Myocardial metabolic and hemodynamic effects of a sustained intravenous infusion of nifedipine with and without metoprolol in patients with unstable angina. We tested the usefulness of a sustained intravenous infusion of nifedipine and a combination of nifedipine and metoprolol in the early management of 14 patients wi... | cardiovascular diseases |
Cerebellar voice tremor: an acoustic analysis. Patients with cerebellar disease may exhibit tremulous phonation as part of their dysarthria. The results of an acoustic analysis of cerebellar voice tremor in a patient with hereditary ataxia and presenting with a purely cerebellar syndrome are reported. Analysis included... | general pathological conditions |
Cytologic diagnosis of aspergillosis in cardiac transplantation. Fine-needle aspiration of the lung is now widely utilized to diagnose pulmonary neoplasms, but often serologic techniques or open-lung biopsy is relied on for the diagnosis of infectious pulmonary processes. We report a series of four patients in whom the... | general pathological conditions |
Insulin resistance and blood pressure in young black men. Insulin resistance, independent of obesity or non-insulin-dependent diabetes mellitus, has been demonstrated to be associated with high blood pressure. To determine if insulin resistance could be an antecedent to hypertension in a high-risk population, we studie... | cardiovascular diseases |
The encased ureter: bullet and bodkin pattern, a reliable radiographic sign. Among the causes of constricted ureter is benign or malignant encasement. The diagnosis of ureteric encasement is frequently overlooked, even by well informed clinicians and radiologists. The most common benign cause is retroperitoneal fibrosi... | general pathological conditions |
Clinical implications of screening for cervical cancer under Medicare. The natural history of cervical cancer in the elderly: what do we know? What do we need to know? Despite the recent passage of coverage for Papanicolaou test screening under Medicare, several aspects of the natural history of cervical cancer in the ... | neoplasms |
Anorectal sensory and motor function in neurogenic fecal incontinence. Comparison between multiple sclerosis and diabetes mellitus. We measured anorectal sensory and motor function in 11 patients with multiple sclerosis and fecal incontinence, 11 continent patients with multiple sclerosis, 10 diabetics with fecal incon... | digestive system diseases |
Echocardiographic assessment of doxazosin on left ventricular mass in patients with essential hypertension. A single daily dose of doxazosin taken during a 12-week period produced a significant reduction in blood pressure and left ventricular mass index in patients with mild or moderate hypertension. The systolic short... | cardiovascular diseases |
Captopril-induced cholestatic jaundice. I have reported a case of captopril-induced cholestatic jaundice. This drug is being used with increasing frequency, so it is important that physicians recognize this adverse effect. Captopril-induced jaundice resolves after cessation of captopril therapy. | general pathological conditions |
Effect of the topical anesthetic EMLA on the efficacy of pulsed dye laser treatment of port-wine stains. EMLA cream (Eutectic Mixture of Local Anesthetics) is a new topical anesthetic composed of 25 mg lidocaine and 25 mg prilocaine in an oil-in-water emulsion cream. It has been found to be very effective for local ane... | neoplasms |
Basal cell carcinoma recurring after radiotherapy: a unique, difficult treatment subclass of recurrent basal cell carcinoma. Twenty-seven basal cell carcinomas (BCCs) recurring following radiation therapy alone or in addition to other treatment modalities were treated with Mohs micrographic surgery (MMS) from 1983 to 1... | neoplasms |
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