text stringlengths 170 4k | label stringclasses 5
values |
|---|---|
Persistent rectal ulcer associated with human papillomavirus type 33 in a patient with AIDS: successful treatment with isotretinoin. Rectal dysplasia and carcinoma associated with human papillomavirus infection are increasing in prevalence among homosexual men, particularly those infected with the human immunodeficienc... | digestive system diseases |
Intraputaminal infusion of nerve growth factor to support adrenal medullary autografts in Parkinson's disease. One-year follow-up of first clinical trial. Experimental studies in rodents show that beta-nerve growth factor can increase the survival, neurite outgrowth, and functional effect of grafts of adrenal chromaffi... | nervous system diseases |
Mycobacterium chelonei keratopathy with visual rehabilitation by a triple procedure. We report a chronic keratouveitis following an eye injury, the etiology of which remained obscure despite repeated corneal scrapings and cultures. Eventually, the diagnosis was established by culturing Mycobacterium chelonei from a cor... | general pathological conditions |
Complications of lateral C1-2 puncture myelography. This study reviewed the technical complication of 112 cases of lateral C1-2 puncture myelography for cervical spinal cord disorders. Spinal cord puncture and contrast injection, puncture between the occiput and C1, and blood vessel puncture were the main complications... | nervous system diseases |
A human CD5+ B cell clone that secretes an idiotype-specific high affinity IgM monoclonal antibody. We previously demonstrated the occurrence of a naturally arisen human anti-idiotypic B cell clone, that we transformed with EBV (EBV383). We show evidence that EBV383 not only expresses the CD5 surface Ag, but also conta... | neoplasms |
Gene rearrangements in the diagnosis of lymphoma/leukemia. Guidelines for use based on a multiinstitutional study. The demonstration of immunoglobulin or T-cell receptor gene rearrangements in human lymphoproliferative processes with the use of DNA hybridization has gained great popularity as a sensitive laboratory adj... | neoplasms |
The response of retroperitoneal fibrosis to tamoxifen. Although retroperitoneal fibrosis is uncommon and histologically benign, it is a progressive and potentially fatal tumor. As the fibroblasts proliferate, they encase and may obstruct important retroperitoneal structures. Medical therapy in the past has been ineffec... | general pathological conditions |
Outpatient percutaneous central venous access in cancer patients. A 1-year experience of percutaneous subclavian catheterization in outpatients with cancer was reviewed to document reliability, safety, and cost. There were 763 catheter insertions attempted with prospective documentation of complications in 664 consecut... | neoplasms |
Sixty consecutive breast reconstructions with the inflatable expander: a critical appraisal. Breast reconstruction using inflatable expanders has become an established and preferred technique. Although our knowledge of the biomechanical changes occurring in expanded skin has increased greatly, little information is ava... | general pathological conditions |
Effect of abrupt mitral regurgitation after balloon valvuloplasty on myocardial load and performance. The concept that mitral regurgitation masks myocardial dysfunction by reducing afterload and augmenting ejection performance has not been well established in humans. The effect of abruptly produced mitral regurgitation... | cardiovascular diseases |
Effect of drug and diet treatment of mild hypertension on diastolic blood pressure. The TAIM Research Group. The Trial of Antihypertensive Interventions and Management is a multicenter randomized trial designed to examine the diastolic blood pressure response of various combinations of pharmacological and dietary inter... | cardiovascular diseases |
The unique aspects of acute promyelocytic leukemia. Acute promyelocytic leukemia (APL) accounts for approximately 10% of cases of acute myeloid leukemia (AML). Distinctive features of this disorder at the time of diagnosis include leukopenia coexisting with a marrow replaced with granulated dysplastic promyelocytes, di... | neoplasms |
Preoperative radiotherapy in operable rectal cancer. The effect of preoperative radiotherapy (31.5 Gy in 3.5 weeks) in operable rectal cancer was examined with respect to resectability and prognosis after two surgical procedures, abdominoperineal resection, or low anterior resection. Preoperative radiation did not infl... | general pathological conditions |
Porokeratoses: immunohistochemical, light and electron microscopic evaluation. Punch biopsy specimens of 14 patients with porokeratosis of Mibelli (n = 1), disseminated superficial porokeratosis (n = 6), disseminated superficial actinic porokeratosis (n = 4), porokeratosis plantaris, palmaris et disseminata (n = 2), an... | general pathological conditions |
Recurrent acute fatty liver of pregnancy associated with a fatty-acid oxidation defect in the offspring. A case of a 29-year-old woman who has had two episodes both clinically and biochemically consistent with acute fatty liver of pregnancy is described. These episodes occurred in two successive pregnancies, and liver ... | digestive system diseases |
Increased glucose metabolism in the medulla of patients with palatal myoclonus. Hypertrophic degeneration of the inferior olivary nuclei is the pathologic substrate for palatal myoclonus, but the physiologic correlate of this finding is uncertain. Using the 2-[18F]fluoro-2-deoxy-D-glucose and PET method, we determined ... | general pathological conditions |
Stimulatory effects of maitotoxin on insulin release in insulinoma HIT cells: role of calcium uptake and phosphoinositide breakdown. In hamster insulinoma (HIT) cells, maitotoxin (MTX) induces a time-dependent and concentration-dependent release of insulin that requires the presence of extracellular calcium. The respon... | neoplasms |
Implications of peritoneal cytology for staging of early pancreatic cancer. Cytologic examination of peritoneal washings was performed in 40 patients with pancreatic ductal adenocarcinoma (35 head, 5 body) whose tumors had been selected as potentially resectable by computed tomographic (CT) findings. Saline (100 mL) wa... | neoplasms |
Surgery or radiation for early cervical cancer. In summary, neither radiation nor surgery is clearly superior. The benefits of surgery include: 1) emotional satisfaction that the tumor has been removed, 2) accuracy of surgical staging, 3) preservation of the ovaries, 4) no secondary uterine cancer (a very uncommon prob... | neoplasms |
Headaches in dementia. We investigated 288 elderly subjects with various degree of dementia, focusing on headaches. Seventy-three of 288 elderly subjects (25.3%) complained of some headaches. The most common type was the tension-type headache, from which 43 of the 73 subjects with headaches (58.9%) suffered. The degree... | nervous system diseases |
Use of H2-receptor antagonists in children. H2-receptor antagonists (H2RAs) have evolved into the mainstay of anti-acid therapy for pediatric patients, replacing antacids and other modes of therapy. Much of the experience and data used for therapeutic decisions in children, however, have been extrapolated from adult st... | digestive system diseases |
Hypomutability in Fanconi anemia cells is associated with increased deletion frequency at the HPRT locus. Fanconi anemia (FA) is an inherited human disorder associated with a predisposition to cancer and characterized by anomalies in the processing of DNA cross-links and certain monoadducts. We reported previously that... | general pathological conditions |
Studies of myocardial protection in the immature heart. V. Safety of prolonged aortic clamping with hypocalcemic glutamate/aspartate blood cardioplegia. This study tests the hypothesis that multidose, hypocalcemic aspartate/glutamate-enriched blood cardioplegia provides safe and effective protection during prolonged ao... | cardiovascular diseases |
Immediate postoperative mammogram for failed surgical excision of breast lesions In a series of 200 consecutive preoperative needle localizations of non-palpable breast lesions, 128 lesions (64%) were calcified and 72 lesions (36%) were noncalcified on preoperative mammograms. Radiographs of the surgical specimen faile... | neoplasms |
Spectral analysis of tremor: understanding the results. Spectral analysis of a tremor record can sometimes produce a spectrum with multiple components of significant amplitude. The problem is to determine whether the presence of several peaks represents the coexistence of separate tremor mechanisms or be a consequence ... | general pathological conditions |
Serial magnetic resonance imaging of hamstring anterior cruciate ligament autografts during the first year of implantation. A preliminary study. A prospective, observational study was performed to document the serial changes in the magnetic resonance signal of devascularized, hamstring ACL autografts during the 1st yea... | general pathological conditions |
Low metastatic potential of clone from murine colon adenocarcinoma 26 increased by transfection of activated c-erbB-2 gene. We investigated the effect of an activated c-erbB-2 gene (also known as ERBB2) on metastatic potential. The c-erbB-2 gene was activated by mutation of the valine at position 659 within the transme... | neoplasms |
Concealed entrainment as a guide for catheter ablation of ventricular tachycardia in patients with prior myocardial infarction. Fifteen consecutive patients with drug-refractory, recurrent, sustained, monomorphic ventricular tachycardia and a history of remote myocardial infarction underwent catheter ablation of ventri... | cardiovascular diseases |
Hyperplastic polyps seen at sigmoidoscopy are markers for additional adenomas seen at colonoscopy. Asymptomatic individuals undergoing screening flexible sigmoidoscopy were prospectively studied. Polyps were found in 185 subjects. The endoscopist recorded an opinion on the polyps' histology based on endoscopic appearan... | neoplasms |
Cardiopulmonary resuscitation and the patient with cancer. The records of 114 cancer patients suffering cardiopulmonary arrests (CPA) during a 3-year period at Memorial Sloan-Kettering Cancer Center (MSKCC) were retrospectively reviewed to identify variables predicting final outcome in these patients. Although 65.7% of... | cardiovascular diseases |
Evolution of fundic argyrophil cell hyperplasia in nonantral atrophic gastritis. Fundic argyrophil cells were studied for a mean period of 68.7 months (range, 11-170) in 18 patients with fundic atrophic gastritis and achlorhydria. Initially, 12 patients had hyperplasia of the argyrophil cells, the severity of which was... | general pathological conditions |
Collis gastroplasty: origin and evolution. In 1957 J. Leigh Collis published his innovative operation for treating the difficult problem of the irreducible hiatal hernia, esophagitis, and stricture. The design of the operation was based on the relatively primitive understanding of hiatal hernia and the newly emerging c... | digestive system diseases |
Detection of colorectal liver metastases using intraoperative ultrasonography. Intraoperative ultrasonography of the liver has been carried out in 99 patients undergoing surgery for colorectal cancer. Palpation of the liver, preoperative abdominal ultrasonography and computed tomography scanning were also performed in ... | neoplasms |
The osteogenetic potential of fracture haematoma. Subperiosteal and intramuscular transplantation of the haematoma. We studied the precise role of the fracture haematoma in healing by the experimental transplantation of the haematoma at two days and four days after fracture of the rat femur to subperiosteal and intramu... | general pathological conditions |
Pancreatic cancer versus chronic pancreatitis: diagnosis with CA 19-9 assessment, US, CT, and CT-guided fine-needle biopsy. The authors prospectively performed serum CA 19-9 assessment, ultrasound (US), computed tomography (CT), and CT-guided fine-needle aspiration biopsy (FNAB) of the pancreas in 81 consecutive patien... | digestive system diseases |
Initial CT findings in 753 patients with severe head injury. A report from the NIH Traumatic Coma Data Bank. In this prospective multicenter study, the authors have examined data derived from the initial computerized tomography (CT) scans of 753 patients with severe head injury. When the CT findings were related to abn... | cardiovascular diseases |
Total knee arthroplasty in obese patients. We examined 182 patients (257 knees) who had had a total knee arthroplasty two to five six years earlier. The patients were grouped into five weight classes. Eighteen patients (twenty-seven knees) were considered moderately obese and twelve patients (twenty-seven knees), sever... | cardiovascular diseases |
Chordoma: a 20-year clinicopathologic review of the experience at Groote Schuur Hospital, Cape Town. Eighteen chordomas (11 females and 7 males) were seen over a 20-year period; 61% of the tumors occurred in the sphenoid region. The youngest patient was 3 years old and had a family history of chordoma. Histologically, ... | neoplasms |
Cranial nerve palsy in childhood acute lymphoblastic leukemia and non-Hodgkin's lymphoma. Forty-five children with acute lymphoblastic leukemia or non-Hodgkin's lymphoma had cranial nerve palsy (CNP) as a complication of their disease. Twenty-two of these children had CNP initially and 23, at relapse, with or without p... | neoplasms |
Family psychoeducation, social skills training, and maintenance chemotherapy in the aftercare treatment of schizophrenia. II. Two-year effects of a controlled study on relapse and adjustment. Environmental-Personal Indicators in the Course of Schizophrenia (EPICS) Research Group. We demonstrated earlier that a novel fa... | general pathological conditions |
Diagnostic value of brush cytology in the diagnosis of bile duct carcinoma: a study in 65 patients with bile duct strictures. Malignant strictures of the extrahepatic bile ducts are difficult to distinguish from benign strictures, particularly in patients with primary sclerosing cholangitis. Because attempts at diagnos... | digestive system diseases |
Prevention of renal disease and conservation of renal function. In summary, we have reviewed some of the most frequently encountered areas of prevention of renal failure in the elderly. They include obstruction, hypertension, drug interaction, and inappropriate use of drugs and the silent killer of the elderly, renal c... | cardiovascular diseases |
Flexible bronchoscopy via the laryngeal mask: a new technique. Malignant tracheal tumours often cause airway obstruction and this may be aggravated by vocal cord paralysis due to invasion of the recurrent laryngeal nerve. Conventional endoscopic techniques performed under general anaesthesia do not give a simultaneous ... | general pathological conditions |
Elective diagnostic laparoscopy. Laparoscopy developed as a science at the turn of the century, and many scientists assisted in the evolution of this technique. However, it was many years before the multiple trocar system was developed that allowed internal organs to be moved and biopsies to be obtained. This has led t... | neoplasms |
Quantitative assessment of cerebral blood volume by single-photon emission computed tomography. We implemented a technique for measuring regional cerebral blood volume using single-photon emission computed tomography and in vivo technetium-99m-labeled red blood cells and then evaluated it in nine normal human volunteer... | cardiovascular diseases |
Endourological treatment of ureteroenteric anastomotic strictures: long-term followup. In 1987 we reported our initial experience with an endosurgical incisional approach to ureteroenteric anastomotic strictures (that is endoureterotomy). We have extended that initial report to encompass 15 patients with 19 ureteroente... | general pathological conditions |
Predicting distant metastases in operable breast cancer patients. Risk factors for distant metastases following mastectomy and axillary node dissection for breast cancer were analyzed in a review of 1022 women. From diagnosis until the end of the adjuvant treatment, six stages were identified that corresponded well to ... | general pathological conditions |
Dispatcher-assisted telephone CPR: common delays and time standards for delivery. STUDY OBJECTIVES: To determine the rate of bystander CPR before and after implementation of a telephone CPR program in King County; to determine the reasons for dispatcher delays in identifying patients in cardiac arrest in delivering CPR... | cardiovascular diseases |
Anterior perforations in lumbar discectomies. A report of four cases of vascular complications and a CT study of the prevertebral lumbar anatomy. Four cases of vascular complications to anterior perforations during discectomy prompted a CT study to measure lumbar disc diameters and to evaluate the prevertebral anatomy.... | general pathological conditions |
Allelic loss of chromosomes 16q and 10q in human prostate cancer. Recent advances in understanding the molecular genetics of common adult tumors have indicated that multiple genetic alterations including the activation of oncogenes and the inactivation of tumor suppressor genes are important in the pathogenesis of thes... | general pathological conditions |
Effective destruction of cervical intraepithelial neoplasia (CIN) 3 at 100 degrees C using the Semm cold coagulator: 14 years experience A total of 1628 women with CIN 3 treated with the Semm cold coagulator between 1975 and 1989 was followed primarily by cytology. The standard suitability criteria for ablation were ad... | neoplasms |
Low dose amitriptyline in chronic pain: the gain is modest. In the double-blind placebo-controlled study presented here, the effects were investigated of a low dose of amitriptyline (75 mg) in patients with chronic pain of various origins. The active drug was superior to placebo in reducing pain intensity. The reductio... | general pathological conditions |
Limitation of myocardial infarct size by a right ventricular assist device. To evaluate the effects of an RVAD on myocardial ischemic injury during right coronary artery (RCA) ligation, a pneumatically driven pusher plate pump was inserted between the right atrium and pulmonary artery, and the RCA was ligated at its or... | general pathological conditions |
Dental patient reaction to electrocardiogram screening. Ninety-one patients receiving routine dental treatment at the University of Minnesota School of Dentistry participated in an electrocardiogram screening study. The purpose of the study was to evaluate patient reaction to electrocardiogram screening in a dental sch... | general pathological conditions |
Aids for visual impairment. This article provides only a flavour of the type and range of aids available to the visually impaired person. Many other aids for leisure, learning, and daily living are illustrated in the RNIB equipment and games catalogue. | nervous system diseases |
Diffuse sclerosing osteomyelitis of the mandible: a new concept of its etiology. Diffuse sclerosing osteomyelitis of the mandible is a disease of unknown etiology. The clinical and radiographic findings suggest an infectious origin, but bacteriologic and histologic findings do not support this concept. Analysis of clin... | general pathological conditions |
Diagnosis and treatment of cytomegalovirus disease in transplant patients based on gastrointestinal tract manifestations. Infection due to cytomegalovirus is a substantial cause of morbidity and mortality in immunocompromised patients. In particular, cytomegalovirus infection has been associated with a significant detr... | digestive system diseases |
Thrombosis-related markers in unstable angina pectoris. While thrombus formation has been implicated in the pathogenesis of unstable angina, the value of thrombus-related markers for distinguishing unstable from stable angina is not well defined. Fibrin D-dimer and plasminogen activator inhibitor were prospectively ana... | cardiovascular diseases |
Primary lymphoma of the liver: clinical and pathological features of 10 patients. Nine out of 10 patients with primary lymphoma of the liver presented in a manner that did not suggest a tumour. The initial diagnoses were chronic active hepatitis in three cases and "granulomatous cholangitis", inflammatory pseudotumour,... | neoplasms |
Pulse oximetry during apparent tonic-clonic seizures. A pulse oximeter was used to monitor arterial oxygen saturations in 11 patients during apparent tonic-clonic seizures. 8 had a clinical diagnosis of genuine fits, 6 of whom showed striking falls in oxygen saturation during the seizures. 3 had a clinical diagnosis of... | nervous system diseases |
Prediction of cognitive change as a function of preoperative ability status among temporal lobectomy patients seen at 6-month follow-up. The relationship between preoperative ability levels and postoperative changes in cognitive function was examined among 23 left (LTL) and 19 right (RTL) temporal lobectomy patients us... | nervous system diseases |
Weight gain with breast cancer adjuvant treatment. Available information suggests that individuals with breast cancer gain weight during adjuvant treatment and that this weight gain may be associated with poor prognosis. Exploration of the factors which affect weight gain may aid in developing weight control interventi... | general pathological conditions |
Deletion mapping of Aland Island eye disease to Xp21 between DXS67 (B24) and Duchenne muscular dystrophy. Aland Island Eye Disease (AIED) is an X-linked form of ocular hypopigmentation--also known as Forsius-Eriksson, or type 2, ocular albinism--in which affected males demonstrate subnormal visual acuity, protanomalous... | general pathological conditions |
Congenital diaphragmatic hernia: impact of prostanoids in the perioperative period. A prospective study of 10 neonates with congenital diaphragmatic hernia and five controls to determine the importance of prostanoid concentrations perioperatively and the relation with persistent pulmonary hypertension (PPH) is reported... | digestive system diseases |
Acute lower respiratory tract infections in hospitalized patients with diarrhea in Dhaka, Bangladesh. This study focused on 401 children less than 5 years old who were hospitalized with acute lower respiratory tract infection (ALRI) and diarrhea in Dhaka, Bangladesh, and who were investigated for the presence of both b... | digestive system diseases |
Delayed onset of cardiac arrhythmias from sustained-release verapamil. Sustained-release products in overdose are known to produce prolonged effects as well as delayed onset. The availability of sustained-release calcium channel blockers may produce an initial misleading picture for patients who are at risk for serious... | cardiovascular diseases |
Mechanisms of blood flow during pneumatic vest cardiopulmonary resuscitation. Mechanisms of blood flow during cardiopulmonary resuscitation (CPR) were studied in a canine model with implanted mitral and aortic flow probes and by use of cineangiography. Intrathoracic pressure (ITP) fluctuations were induced by a circumf... | cardiovascular diseases |
Atopy and primary lung cancer. Histology and sex distribution. Atopy, defined as the ability to develop IgE antibodies to commonly encountered allergens under conditions of normal exposure, has an inherited component with pleiotropic effects. An inverse relationship between the occurrence of atopy, allergy-related dise... | neoplasms |
Cat-scratch disease: an unusual cause of combative behavior. Acute encephalitis is an unusual manifestation of cat-scratch disease. The authors present the case of a 27-year-old man who exhibited the acute onset of encephalitis manifested by violent behavior and confusion. The diagnosis of drug abuse was presumed initi... | nervous system diseases |
Treatment of severe acne with isotretinoin in patients with inflammatory bowel disease. Four patients with inflammatory bowel disease and severe cystic acne were treated with isotretinoin. Two patients had a successful course of treatment without any gastrointestinal side-effects. One patient had two episodes of profus... | general pathological conditions |
A prospective study of patients with sciatica. A comparison between conservatively treated patients and patients who have undergone operation, Part II: Results after one year follow-up. The prospective study included 122 sciatica patients who had not undergone operation (NOPs) and 220 sciatica patients who had undergon... | general pathological conditions |
Infrainguinal bypass surgery: factors determining late graft patency. The results of 373 infrainguinal bypass grafts, in a single centre, between 1980 and 1988 are reviewed. One hundred and thirty in situ vein (ISV), 47 reversed saphenous vein (RSV), 118 polytetrafluoroethylene (PTFE) and 78 human umbilical vein (HUV) ... | cardiovascular diseases |
Improved early detection of recurrence in prostatic carcinoma following hormonal therapy. Combined use of palpation and fine needle aspiration cytology. Fifty-nine hormonally treated prostatic carcinoma patients were prospectively followed by rectal examination and fine needle aspiration cytology at six-month intervals... | neoplasms |
Surgical presentation of Kawasaki disease (mucocutaneous lymph node syndrome). Five patients with Kawasaki disease (mucocutaneous lymph node syndrome) are reported whose varied presentations included acute abdominal pain, peripheral arterial aneurysms, digital gangrene and sterile pyuria and whose presenting pathology ... | cardiovascular diseases |
Improved flow cytometric determination of proliferative activity (S-phase fraction) from paraffin-embedded tissue. Recent studies suggest that proliferative activity (S-phase fraction [SPF]) may have greater prognostic significance than total nuclear DNA content; however, relatively few studies have examined SPF from p... | general pathological conditions |
Patient factors predicting early alcohol-related readmissions for alcoholics: role of alcoholism severity and psychiatric co-morbidity. The current study was undertaken primarily to identify whether psychiatric co-morbidity was associated with the rate and time of alcohol-related inpatient readmissions for a group of 2... | general pathological conditions |
Patients with two types of atrioventricular junctional (AV nodal) reentrant tachycardia. Evidence that a common pathway of nodal tissue is not present above the reentrant circuit. BACKGROUND. The site of the reentrant circuit in atrioventricular (AV) junctional reentrant tachycardia has not been defined; in particular,... | cardiovascular diseases |
Improved scintigraphic assessment of severe cholestasis with the hepatic extraction fraction. In previous studies, we found that biliary scintigraphy with technetium-99m-labeled iminodiacetic acid ([99mTc]IDA) provided excellent discrimination between intrahepatic and extrahepatic cholestasis, except in patients with p... | general pathological conditions |
Neglected factors in chronic pain treatment outcome studies--referral patterns, failure to enter treatment, and attrition. An increasing number of chronic pain treatment outcome studies have appeared in the literature. In general, these studies support the efficacy of multidisciplinary pain programs, as well as specifi... | nervous system diseases |
Recurrent acute fatty liver of pregnancy associated with a fatty-acid oxidation defect in the offspring. A case of a 29-year-old woman who has had two episodes both clinically and biochemically consistent with acute fatty liver of pregnancy is described. These episodes occurred in two successive pregnancies, and liver ... | general pathological conditions |
Pain control in the ambulatory elderly. Pain control in the elderly, no matter what the etiology or setting, can be a major clinical challenge. Aging causes unique physiologic changes, eg, a decreased perception of pain and an enhanced sensitivity to opioid analgesics. Principles regarding evaluation of patients with p... | nervous system diseases |
Disseminated zygomycosis associated with systemic lupus erythematosus. We describe a 36-year-old patient who had systemic lupus erythematosus (SLE) and died of disseminated zygomycosis. There was rapid progression of his SLE, leading to suspicion of superimposed infectious disease, but the actual cause of his multiorga... | general pathological conditions |
Angiotensin-converting-enzyme inhibitors and anaphylactoid reactions to high-flux membrane dialysis In a retrospective study, 9 of 236 haemodialysis patients treated with high-flux polyacrylonitrile 'AN 69' membranes were found to have had anaphylactoid reactions. Treatment with angiotensin-converting-enzyme (ACE) inhi... | general pathological conditions |
Giant breast hematoma requiring blood transfusion: an unusual complication after an echocardiographic study during thrombolytic therapy. We report on a patient in whom significant bleeding occurred during thrombolytic therapy. The bleeding occurred after an echocardiographic study, and it resulted in blood transfusion.... | general pathological conditions |
Capsular genu syndrome. We report 5 patients with unilateral infarct and 1 with hemorrhage limited to the genu of the internal capsule. The most prominent finding was contralateral facial and lingual hemiparesis with dysarthria. Three patients also showed unilateral mastication-palatal-pharyngeal weakness, and 1 had un... | general pathological conditions |
Anaesthetic problems in ex situ resection of the liver. Ex-situ resection of the liver is a new surgical technique for treatment of liver tumours not amenable to conventional surgery. This paper describes the cardiovascular and metabolic changes that occurred in nine consecutive such patients. No severe haemodynamic or... | general pathological conditions |
Prospective pharmacokinetically based development of effective infusion regimens for ACC-9358, a new antiarrhythmic drug. In this study we evaluated the clinical pharmacology of intravenous ACC-9358, a new antiarrhythmic drug derived from a Chinese herbal remedy. In a first-study phase, 0.125 to 1.0 mg/kg during 10 min... | general pathological conditions |
Adrenal hormones and the anorectic response and adaptation of rats to amino acid imbalance. The role of adrenal function in the anorectic response and adaptation of rats to a diet with an isoleucine (Ile) imbalance was investigated. In the first of four experiments, rats were fed a mildly Ile-imbalanced diet after trea... | general pathological conditions |
Assessment of myocardial perfusion in patients after the arterial switch operation. In 21 patients who had undergone the arterial switch operation, the adequacy of myocardial perfusion was evaluated by thallium-201 computed scintigraphy 2.6 +/- 2 (0.3-7) yr after surgery. Fourteen patients had undergone the arterial sw... | cardiovascular diseases |
Cause of thrombosis in human atherosclerotic arteries. Although it has been known for a long time that thrombosis nearly always develops in atherosclerotic arteries--and almost never in normal vessels--the mechanism through which atherosclerosis promotes thrombosis was unknown until this problem was explored through hi... | general pathological conditions |
Respiratory symptoms and risk factors in an Arizona population sample of Anglo and Mexican-American whites. Prevalence rates of respiratory symptoms and diseases in a large group of Anglos and Mexican-Americans were analyzed. Each subject completed a questionnaire. Among current smokers, chronic productive cough and dy... | general pathological conditions |
Regeneration of myocardial phosphocreatine in pigs despite continued moderate ischemia. The effects of 1 hour of mild and moderate reductions in coronary blood flow on myocardial high-energy phosphate levels were evaluated. Thirty anesthetized pigs were instrumented with left anterior descending arterial and venous cat... | cardiovascular diseases |
Removal of radiation-induced cataracts in patients treated for retinoblastoma. Experience with removal of radiation-induced cataract in patients treated for retinoblastoma is limited. We retrospectively reviewed the records of 38 patients with retinoblastoma (42 eyes) who underwent removal of radiation-induced cataract... | neoplasms |
Adrenergic control of the internal anal sphincter is abnormal in patients with idiopathic faecal incontinence. There is histological and functional evidence that the internal anal sphincter is abnormal in patients with idiopathic faecal incontinence. The in vitro responsiveness of the internal anal sphincter to noradre... | digestive system diseases |
Popliteal aneurysms identified by intra-arterial streptokinase: a changing pattern of presentation. Five patients presenting with chronic or subacute leg ischaemia due to thrombosed popliteal artery aneurysm are described. Only one of these aneurysms was diagnosed before intra-arterial streptokinase infusion, which suc... | cardiovascular diseases |
Effects of carotid denervation and decerebration on ventilatory response to CO. To clarify the mechanisms involved in the ventilatory response to the inhalation of low concentrations of CO (0.18-0.22% in air), the roles of the arterial chemoreceptors and the forebrain structures have been investigated in unanesthetized... | nervous system diseases |
Matched group study of surgical resection versus cobalt-60 plaque radiotherapy for primary choroidal or ciliary body melanoma. We report the results of a nonrandomized, matched-group, survival and visual preservation study of patients with a choroidal or ciliary body melanoma managed by microsurgical resection of the t... | neoplasms |
Cyclophosphamide and ifosfamide combination as neoadjuvant chemotherapy for locally advanced nonsmall-cell lung cancer: a meta-analytic review. Twenty-three patients with marginally resectable and unresectable non-small-cell lung cancer (stages IIIA and IIIB) were treated by neoadjuvant chemotherapy. All patients recei... | neoplasms |
Effects of head trauma from motor vehicle accidents on Parkinson's disease. During 1 year we monitored changes in clinical disability scores in 10 patients with Parkinson's disease (PD) who sustained head trauma from motor vehicle accidents. Disability significantly increased immediately after trauma, but returned to b... | nervous system diseases |
Palliative operations for colorectal cancer. A review of 96 consecutive patients who underwent palliative surgery for primary colorectal cancer was undertaken to clarify the value of palliation achieved with surgical treatment. The overall rate of postoperative mortality was 8 percent (8 of 96) and the overall rate of ... | general pathological conditions |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.