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Ischaemic brain lesions diagnosed at birth in preterm infants: clinical events and developmental outcome. In 232 newborn babies of less than 32 weeks' gestational age ultrasound brain scans were carried out shortly after birth, daily for the first week of life, and at least twice weekly thereafter. Periventricular echo... | nervous system diseases |
Effects of hypothyroidism on bronchial reactivity in non-asthmatic subjects. The effect of hypothyroidism on non-specific bronchial reactivity was studied in 11 patients without pulmonary disease (mean age 40 (SD 13) years) who had had a total thyroidectomy and radioiodine treatment for thyroid cancer 41 (36) months be... | neoplasms |
An extracorporeal perfusion system to bridge pediatric liver transplant candidates. An extracorporeal liver perfusion system was designed to maintain cadaver livers in an oxygenated, normothermic state for bridging procedures for hepatic transplantation. Nonpulsatile high flow and pulsatile low flow blood are supplied ... | nervous system diseases |
Apparent reduction in the size of one side of the face associated with a small retrosplenial haemorrhage. A 68 year old Japanese female with unilateral metamorphopsia of the face that developed after a small haemorrhage in the contralateral retrosplenial region, is described. The patient claimed that the right side of ... | nervous system diseases |
The effects of methoxamine and epinephrine on survival and regional distribution of cardiac output in dogs with prolonged ventricular fibrillation This study compares the effects of methoxamine, a pure alpha 1-agonist, and epinephrine on cerebral and myocardial blood flow, central hemodynamics, and survival in a random... | general pathological conditions |
Role of epidermal growth factor, prostaglandin, and sulfhydryls in stress-induced gastric lesions. Epidermal growth factor promotes the growth of and protects gastric mucosa against various ulcerogens, including stress, but little is known about its role in the pathogenesis of stress ulcerations. In this study, Wistar ... | digestive system diseases |
Malignant mixed tumor (malignant ameloblastoma and fibrosarcoma) of the maxilla. We present a rare case of carcinosarcoma (malignant ameloblastoma and fibrosarcoma) of the left maxilla that developed in a 63-year-old Japanese man. The tumor recurred repeatedly despite multiple surgical removals, radiotherapy, and chemo... | neoplasms |
Influence of chemotherapy administration on monocyte activation by liposomal muramyl tripeptide phosphatidylethanolamine in children with osteosarcoma. The purpose of these studies was to determine whether chemotherapy interfered with the ability of peripheral blood monocytes from patients with osteosarcoma to respond ... | neoplasms |
Comparison of postmortem magnetic resonance imaging and neuropathologic findings in the cerebral white matter. Two types of high-signal intensity abnormalities are frequently found bilaterally in the cerebral white matter of brains of elderly patients on T2-weighted magnetic resonance imaging (MRI) scans. One is locate... | general pathological conditions |
Antigen related to cell proliferation in malignant gliomas recognized by a human monoclonal antibody. A human monoclonal antibody (CLN-IgG) was produced from a human-human hybridoma derived from lymphocytes of a patient with cervical carcinoma. The reactivities of this antibody with various human glioma tissues and cul... | neoplasms |
Dysgeusia, gustatory sweating, and crocodile tears syndrome induced by a cerebellopontine angle meningioma. Facial nerve involvement in cerebellopontine angle tumors, both during their development and after excision, may be expressed in irreversible dysfunction of the parasympathetic pathways. The exact location of the... | general pathological conditions |
Quantifying the potential benefit of CA 125 screening for ovarian cancer. We develop a stochastic model of screening for ovarian cancer with serum levels of the CA 125 radioimmunoassay, a tumor-specific marker. The natural history of the disease is constructed using a four stage model characterized by a multivariate di... | neoplasms |
Syringomyelia as a postoperative sequela of the resection of a chordoma of the clivus: case report. Syringomyelia has been described frequently in association with various abnormalities of the skull base but rarely with tumors of the skull base. Syringomyelia as a postoperative sequela of surgery of the skull base has ... | nervous system diseases |
Epidermal growth factor regulates the in vitro sensitivity of human ovarian carcinoma cells to cisplatin. Cisplatin (DDP) is the most effective drug for the treatment of human ovarian cancer, but the mechanisms that determine sensitivity to the cytotoxic action of DDP are not well understood. Treatment of two human ova... | neoplasms |
Preferential mitogenic activity for myoblast-like cells can be extracted from uterine leiomyoma tissues. The presence of mitogen(s) in leiomyoma extracts stimulating cells with the fibroblast, myoblast, and osteoblast phenotype was documented. Mitogenic activity in leiomyoma extracts was acid stable and sensitive to tr... | neoplasms |
Atracurium decay and the formation of laudanosine in humans. Several groups of investigators have reported that the plasma concentrations of laudanosine, a metabolite of atracurium, are high immediately after administration of atracurium and thereafter decline. Such a time profile of a metabolite in plasma is very unus... | digestive system diseases |
Diagnosis of chronic abacterial prostato-vesiculitis by rectal ultrasonography in relation to symptoms and findings. A group of 36 men with chronic abacterial prostato-vesiculitis, confirmed by semen analysis and rectal ultrasonography, underwent detailed anamnesis and clinical examination. There was no clear relations... | general pathological conditions |
Norfloxacin prevents spontaneous bacterial peritonitis recurrence in cirrhosis: results of a double-blind, placebo-controlled trial. Eighty cirrhotic patients who had recovered from an episode of spontaneous bacterial peritonitis were included in a multicenter, double-blind trial aimed at comparing long-term norfloxaci... | digestive system diseases |
Should safety concerns with available ulcer treatment influence drug selection? With the identification of the parietal cell receptors for gastric acid secretion coupled with the introduction of cimetidine in 1977, treatment of acid-peptic diseases was transformed from empiric therapy to an approach based on a clearer ... | digestive system diseases |
Diffuse proliferative lupus nephritis: long-term observations in patients treated with ancrod. Twenty-two patients with histologically demonstrated diffuse proliferative lupus nephritis (DPLN) and glomerular thrombosis received a 14-day course of ancrod, followed in most by nitrogen mustard (mechlorethamine hydrochlori... | cardiovascular diseases |
Characteristics of duodenal wall gastrinomas. Fifteen patients with duodenal wall gastrinomas (DWGs) and the Zollinger-Ellison syndrome have been treated since 1960. In 6 of 11 patients, DWGs were recognized at operation and totally excised. In four patients, the tumor was subsequently found in the proximal duodenum of... | neoplasms |
Treatment of malignant pleural effusions with doxorubicin hydrochloride-containing poly(L-lactic acid) microspheres. For the treatment of malignant pleural effusions, we prepared doxorubicin hydrochloride (Adriamycin)-containing poly(L-lactic acid) microspheres (ADR-MS). In vitro, 50 percent and 100 percent release tim... | neoplasms |
Atonic pupil: an unusual complication of cataract surgery. Eight cases of atonic pupil, an unusual complication following cataract surgery, are presented. Six of the eyes involved had intracapsular cataract extraction and anterior chamber intraocular lens implantation; one case underwent extracapsular cataract extracti... | general pathological conditions |
The influence of age vs peak serum concentration on life-threatening events after chronic theophylline intoxication. To identify risk factors for the development of seizures and cardiac arrhythmias after chronic, unintentional theophylline intoxication we monitored the clinical course of 72 consecutive patients referre... | general pathological conditions |
Angiocentric lymphoma with histologic features of neoplastic angioendotheliomatosis presenting with predominant respiratory and hematologic manifestations. Report of a case and review of the literature Neoplastic angioendotheliomatosis (NAE) is a rare fatal disease characterized by widespread intravascular proliferatio... | neoplasms |
Sudden death from acute cocaine intoxication in Virginia in 1988. A review of medical examiners' autopsy records revealed that in 1988, 33 residents of Virginia died of acute cocaine intoxication. The subjects were 19 to 45 years old; most were men, used cocaine intravenously, and used other toxic substances with the l... | cardiovascular diseases |
Effects of local reduction in pressure on distensibility and composition of cerebral arterioles. This study examined effects of local reductions in mean and pulse pressures on cerebral arterioles in normotensive Wistar-Kyoto rats (WKY) and stroke-prone spontaneously hypertensive rats (SHRSP). WKY and SHRSP underwent cl... | general pathological conditions |
src expression in small-cell lung carcinoma and other neuroendocrine malignancies. The proto-oncogene c-src codes for two tyrosine kinases, pp60c-src and pp60c-srcN. The latter protein appears to be exclusively expressed in neurons and neuronally differentiated tumors. In cell lines derived from neuroblastoma and small... | neoplasms |
Normal small bowel biopsy followed by coeliac disease. We report four patients (two children, one adolescent, and one adult) having normal small bowel mucosa shown on a biopsy specimen taken before the initial diagnosis of coeliac disease was made. The first biopsy was undertaken in two cases because of suspected malab... | digestive system diseases |
Recurrence of duodenal ulcer and elevated serum pepsinogen I levels in smokers and nonsmokers. We determined serum pepsinogen I (PG I) levels by radioimmunoassay in 472 patients with duodenal ulcer and 141 normal subjects to investigate whether serum PG I levels were related to cigarette smoking, and in 225 patients to... | digestive system diseases |
Tracheoesophageal anastomosis for intractable aspiration pneumonia. Permanent tracheostomy and tracheoesophageal anastomosis were performed as a means of surgical intervention for the treatment of intractable aspiration pneumonia. Conventional methods of tracheoesophageal anastomosis have entailed various problems. The... | nervous system diseases |
Selected neurologic complications of pregnancy. Many neurologic disorders, such as eclampsia, pseudotumor cerebri, stroke, obstetric nerve palsies, subarachnoid hemorrhage, pituitary tumors, and choriocarcinoma, can develop in the pregnant patient. Maternal mortality from eclampsia, which ranges from 0 to 14%, can be d... | nervous system diseases |
Successful CPR in a severely hypothermic patient using continuous thoracostomy lavage. Severe hypothermia with cardiopulmonary arrest often requires prolonged resuscitation while rewarming procedures are implemented. A 63-year-old male in cardiopulmonary arrest with a core body temperature of 23.7 C was resuscitated su... | cardiovascular diseases |
Modified technique of Pringle's maneuver in resection of the liver. Crushing of the hepatic parenchyma with hepatic clamps to minimize blood loss during resection of the liver leads to mechanical damage of hepatocytes. Pringle's maneuver may precipitate liver failure by hepatic warm ischemia as well. Therefore, we cont... | general pathological conditions |
Ultrasound-Doppler diagnosis of Budd-Chiari syndrome. We report a case of apparently idiopathic Budd-Chiari syndrome, diagnosed by ultrasound and Doppler sonography, in a patient with latent myeloproliferative disease. This case proves that Doppler sonography shows in the hepatic veins a flow pattern suggestive of part... | cardiovascular diseases |
Attenuated neuropathology by nilvadipine after middle cerebral artery occlusion in rats. We investigated the effects of nilvadipine, a calcium antagonist, on cerebral ischemia in rats. Under halothane anesthesia, 30 rats had a 3-0 nylon suture introduced through the extracranial internal carotid artery to occlude the l... | cardiovascular diseases |
Moustache appearance in craniopharyngiomas: unique magnetic resonance imaging and computed tomographic findings of perifocal edema. This report describes two cases of craniopharyngioma with perifocal edema. In both patients, computed tomography and magnetic resonance imaging (MRI) revealed that the tumors occupied the ... | nervous system diseases |
Influence of hepatitis delta virus replication in the presence of hepatitis B virus DNA in peripheral blood mononuclear cells. The presence of hepatitis B virus DNA was studied in peripheral blood mononuclear cell samples from 259 HBsAg carriers (229 anti-hepatitis delta negative, 30 anti-hepatitis delta positive), 16 ... | digestive system diseases |
Modified anterior compartment resection. In the majority of patients with soft tissue sarcomas of the anterior compartment of the thigh, it is possible to preserve a small portion of the quadriceps with intact nerve supply without compromising on the radicality of the procedure or the local control rate. The distal one... | neoplasms |
Occupational exposure and head and neck carcinoma. An epidemiological case-control study was conducted to investigate occupational risk factors in cancers of the upper respiratory and digestive tract. Cases were men with squamous cell carcinoma of the oropharynx (667), hypopharynx (348), glottis (246), supraglottis (21... | neoplasms |
A retinoic acid response element is part of a pleiotropic domain in the phosphoenolpyruvate carboxykinase gene. Several hormones, including insulin, glucagon, and glucocorticoids, regulate the expression of the rate-limiting gluconeogenic enzyme, phosphoenolpyruvate carboxykinase [GTP: oxaloacetate carboxy-lyase (trans... | neoplasms |
Use of activated charcoal to reduce elevated serum phenobarbital concentration in a neonate. The course of a neonate administered activated charcoal orally for elevated phenobarbital concentration is described. The neonate required a serum concentration of phenobarbital eventually exceeding 80 micrograms/mL for seizure... | nervous system diseases |
Cardiac conducting tissue. A simplified technique for examination of the SA and AV nodes. We describe a modified method for examination of the atrioventricular and sinoatrial nodes that displays the major elements of the cardiac conducting system, yet is not time-consuming for the technician. We examined 31 cases in th... | general pathological conditions |
Ligation of the superficial femoral vein in prevention of pulmonary embolism: an old fashion procedure? From 1974 to 1988, interruption of the superficial femoral vein (SFV) was performed to prevent pulmonary embolism (PE) in 73 patients. The mean age of the patients was 62 years. Phlebography showed thrombi in the fol... | cardiovascular diseases |
Studies of controlled reperfusion after ischemia. XXI. Reperfusate composition: superiority of blood cardioplegia over crystalloid cardioplegia in limiting reperfusion damage--importance of endogenous oxygen free radical scavengers in red blood cells. Postischemic damage is caused partially by oxygen free radical-media... | general pathological conditions |
Research and policy directions. Salt and blood pressure. The relation between dietary intake of sodium chloride and blood pressure levels remains controversial. The critical questions concern whether there is a susceptible subgroup at risk of elevated blood pressure because of sodium chloride consumption. If there is s... | general pathological conditions |
Myocardial perfusion-contraction matching. Implications for coronary heart disease and hibernation. Experimental studies demonstrate that short-term regional perfusion-contraction matching, in which the energy demands of regional myocardial contraction are reduced to match the diminished myocardial substrate supply, oc... | cardiovascular diseases |
Electrocardiographic signal-averaging during atrial pacing and effect of cycle length on the terminal QRS in patients with and without inducible ventricular tachycardia. Electrocardiographic signal-averaging during sinus rhythm (61 to 99 beats/min) and atrial pacing (100 to 171 beats/min) were performed to determine th... | cardiovascular diseases |
Lightning injury with lung bleeding in a tracheotomized patient. A 68-year-old man, who had undergone laryngectomy six months earlier, was struck by lightning and developed pulmonary hemorrhage. This was attributed to pulmonary barotrauma due to a lightning blast via his tracheostoma. | general pathological conditions |
Effective doses of epidural morphine for relief of postcholecystectomy pain. Having previously established the effective dose of intrathecal morphine for relief of postcholecystectomy pain, we determined in this study the effective dose of epidural morphine for relief of postcholecystectomy pain in 154 patients given e... | general pathological conditions |
Leukotriene synthesis inhibition and receptor blockade do not inhibit hypoxic pulmonary vasoconstriction in sheep. Several lines of evidence suggest that leukotrienes may be mediators of hypoxic pulmonary vasoconstriction (HPV). However, the effect of leukotriene inhibition on HPV remains controversial. The present stu... | general pathological conditions |
Analysis of antigen expression at multiple tumor sites in epithelial ovarian cancer. The question of whether the antigenic phenotype of human epithelial ovarian cancer varies in a given patient between the primary tumor and metastatic sites or among metastatic sites themselves is an important issue in planning potentia... | general pathological conditions |
Nausea, vomiting, and retching. Although nausea, vomiting, and retching have plagued mankind since antiquity, limited attention has been given to the three symptoms as separate entities. Although knowledge of symptom occurrence is essential to practice, nurses must focus on patients' response or distress to the occurre... | digestive system diseases |
Infantile CNS spongy degeneration--14 cases: clinical update. We studied 14 Arab infants with infantile spongy degeneration, 13 of whom were products of consanguineous marriages. They presented in infancy with macrocephaly, poor visual behavior or blindness, and axial hypotonia with appendicular spasticity. Brain CT an... | nervous system diseases |
Blood rheology after cardiac valve replacement with mechanical prostheses or bioprostheses. Arterial thromboembolism is a serious complication in patients after heart valve replacement. Abnormalities in blood rheology may contribute to this complication. Therefore, the aim of this study was to compare various determina... | general pathological conditions |
Hemangiopericytoma of the sternum. Hemangiopericytoma of the chest wall is a rare tumor. We describe a patient with malignant hemangiopericytoma of the sternum who was treated with primary surgical resection and discuss the clinical, radiographic, and histologic features of the case. Surgical resection is the primary m... | neoplasms |
Conservative management or closed nailing for tibial shaft fractures. A randomised prospective trial. We performed a prospective randomised trial on matched groups of patients with displaced tibial shaft fractures to compare conservative treatment with closed intramedullary nailing. The results showed conclusively that... | general pathological conditions |
Nontuberculous mycobacterial infections of the skin. Report of fourteen cases and review of the literature. This study comprised 14 patients from whose skin nontuberculous mycobacteria were recovered. Most clinical manifestations were relatively nonspecific. Various histopathologic patterns were observed in 22 biopsy s... | general pathological conditions |
Adult respiratory distress syndrome after limited resection of adenocarcinoma of the lung. Two cases of the adult respiratory distress syndrome developed after limited resection for lung carcinoma. No other known precipitants were evident. The adult respiratory distress syndrome is a clinical expression of acute lung i... | neoplasms |
DNA ploidy pattern in rectal carcinoid tumors. The nuclear DNA pattern of 22 rectal carcinoids was determined by cytophotometry of paraffin embedded tissues. The results were compared with clinical as well as histopathologic features of the tumor. Three of the carcinoids with synchronous or metachronous metastasis had ... | neoplasms |
Self-report of physical activity and patterns of mortality in Seventh-Day Adventist men. The Adventist Mortality Study provides 26-year follow-up through 1985 for 9484 males who completed a lifestyle questionnaire in 1960. The relationship of self-reported physical activity and all cause and disease-specific mortality ... | cardiovascular diseases |
Endothelial cell biology. The endothelium is not a passive blood-compatible lining for the containment of blood cells and plasma, but rather it is a metabolically active tissue that subserves a wide range of functions relating to vascular homeostasis. This article reviews the current understanding of endothelial cell b... | general pathological conditions |
Selective uptake of toxic nucleoside (125IUdR) by resistant cancer. We report uptake of a thymidine analogue 125-Iodine-5-iodo-2'-deoxyuridine (125IUdR) by nude mice bearing human xenografts of choriocarcinoma or colonic cancer. When 125IUdR was given alone, uptake by intestinal tissues was 5-10 times greater than by t... | neoplasms |
Change in sympathetic activity before, during, and after dialysis-induced hypotension. During the hemodialyses of eight patients with end-stage renal failure, who often had sudden-onset dialysis-induced hypotension, catecholamine (CA) levels were measured in the ultrafiltrate obtained by a mini-filter placed in series ... | cardiovascular diseases |
Prolongation of ventricular refractoriness by class Ia antiarrhythmic drugs in the prevention of ventricular tachycardia induction. The effects of class la antiarrhythmic drugs (procainamide, quinidine) on the right ventricular effective refractory period (VERP) and intraventricular conduction time were assessed during... | cardiovascular diseases |
Pregnancy associated with Gorlin's syndrome. A pregnant woman with Gorlin's syndrome presented for the removal of malignant ovarian tumours. The main problem encountered by the anaesthetists was an unexpected increase in arterial blood pressure. This was most probably associated with surgical manipulation of the ovarie... | general pathological conditions |
Medical treatment and prevention of peptic ulcer disease. Many agents seem to be equally effective for the treatment of peptic ulcer disease. This is true despite the drugs' varied mechanisms of action, and this observation has caused investigators to shift their focus from aggressive to defensive factors when studying... | general pathological conditions |
Flow patterns in dilated cardiomyopathy: a pulsed-wave and color flow Doppler study. In 48 patients with dilated cardiomyopathy, pulsed-wave and color Doppler examination were performed. In addition, 14 normal patients served as control subjects. Peak inflow velocity at the level of the mitral valve, middle left ventri... | cardiovascular diseases |
Effects of acute ethanol ingestion and burn injury on serum immunoglobulin. Previous studies have found that acute ethanol ingestion before burn injury caused further impairment of mitogenic response of B lymphocytes compared with burn injury alone. The principal role of B lymphocytes is immunoglobulin production. This... | general pathological conditions |
HIV associated systemic necrotizing vasculitis. The spectrum of HIV associated rheumatic syndromes continues to expand as does our experience with the disease. The following is a case of HIV associated systemic necrotizing vasculitis documented by rectal biopsy. The patient was treated successfully with corticosteroids... | general pathological conditions |
Left atrial to femoral arterial bypass using the biomedicus pump for operations of the thoracic aorta. Left atrial to left femoral arterial bypass is an approach to operations of the thoracic aorta dating back to the late 1950s. Since that time, various modifications of the basic bypass circuit have evolved. In additio... | general pathological conditions |
Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-lipoxygenase inhibitor BACKGROUND AND METHODS. The clinical importance of leukotrienes in human allergy has not been defined, in part because there have been no selective 5-lipoxygenase inhibitors that have been effective and sa... | general pathological conditions |
Obstructed total anomalous pulmonary venous return. Toward neutralization of a major risk factor. Among 57 neonates undergoing repair of total anomalous pulmonary venous return with severe pulmonary venous obstruction from 1980 through 1989, date of operation (1980 to 1984), preoperative hemodynamic instability, and fa... | general pathological conditions |
Calcium, parathyroid hormone, and vitamin D in the "prehypertensive" Dahl salt-sensitive rat. The purpose of this study was to determine if alterations of calcium and calcium regulating hormones precede the onset of NaCl-induced hypertension in the Dahl salt-sensitive (S) rat. After a 5-day balance study, serum ionized... | cardiovascular diseases |
Follow-up recatheterization after balloon aortic valvuloplasty. Mansfield Scientific Aortic Valvuloplasty Registry Investigators. The results of recatheterization were assessed in a select group of 95 patients enrolled in the Mansfield Scientific Aortic Valvuloplasty Registry to determine whether any procedural or pati... | general pathological conditions |
Time of onset of supraventricular tachyarrhythmia in relation to alcohol consumption. It is widely believed but has never been proved that idiopathic supraventricular tachyarrhythmias beginning during or after weekends or winter holidays are frequently alcohol-related ("holiday heart" syndrome). The time of arrhythmia ... | cardiovascular diseases |
Clinicopathologic features of hepatocellular carcinoma in young patients. To investigate clinicopathologic characteristics of hepatocellular carcinoma (HCC) in young adults, excised tumors from 21 patients younger than 45 years (young group) were compared with findings in tumors from 204 patients older than 45 (old gro... | digestive system diseases |
Impact of echocardiography on the management of patients with mitral valve prolapse OBJECTIVE: To determine whether echocardiography affects the decisions to use beta blockers or to recommend bacterial endocarditis prophylaxis in patients suspected of having mitral valve prolapse (MVP). DESIGN: Retrospective review of ... | cardiovascular diseases |
Clinical-computed tomographic correlations of lacunar infarction in the Stroke Data Bank. Lacunar stroke was diagnosed in 337 (26%) of the 1,273 patients with cerebral infarction among the 1,805 total in the Stroke Data Bank. We analyzed the 316 patients with classic lacunar syndromes. Among these, 181 (57%) had pure m... | general pathological conditions |
Lumbar spinal nerves in the neural foramen: MR appearance. The appearance of the proximal lumbar spinal nerves at magnetic resonance (MR) imaging has not, to the authors' knowledge, been described. MR images and exactly corresponding sections obtained from four cadavers by means of a freezing microtome were correlated ... | general pathological conditions |
Endotoxin requirements for alveolar macrophage stimulation. Acute pulmonary failure or ARDS in severely injured patients continues to be a significant problem. The most important clinical risk factor identified is sepsis syndrome. Sepsis syndrome is the clinical correlate of a malignant systemic inflammatory process an... | general pathological conditions |
Nonendoscopic percutaneous gastrostomy. Tight peritoneal adherence of the stomach to the abdominal wall as a prerequisite of percutaneous gastrostomy can be achieved by a newly developed cannula. It serves for puncture and fixation of the gastric wall. Thus, percutaneous gastrostomy can be established safely even in in... | neoplasms |
Surgical treatment of the retethered spinal cord after repair of lipomyelomeningocele. In a series of 75 patients with surgically treated lipomyelomeningoceles, the neurological condition of six patients deteriorated 6 months to 14 years after the operation due to repeat tethering of the spinal cord. The tethering resu... | nervous system diseases |
Fractures of the clivus: classification and clinical features. Fractures of the clival complex were diagnosed in a series of 17 patients admitted to the Maryland Institute for Emergency Medical Services System and the University of Maryland Medical System over a 30-month period. These fractures were divided pathologica... | nervous system diseases |
Recurrent subacute torsion: prospective study of effects on testicular morphology and function. A prospective study was done on 43 consecutive patients with a diagnosis of recurrent subacute testicular torsion. All patients underwent full examination, hormonal assays and seminal fluid analysis before scrotal exploratio... | general pathological conditions |
Retinal arterial macroaneurysms: risk factors and natural history. A case control study was conducted to identify the systemic and ocular risk factors for retinal arterial macroaneurysms. Forty-three patients with 52 photographically confirmed macroaneurysms were located. Forty-three age-matched, race-matched concurren... | cardiovascular diseases |
Treatment with desmopressin acetate in routine coronary artery bypass surgery to improve postoperative hemostasis. Desmopressin acetate (DDAVP) has been shown to decrease blood loss and transfusions in complex cardiac operations with long extracorporeal times. Its use in routine cardiac valve operations has been shown ... | general pathological conditions |
Antinociceptive interaction between opioids and medetomidine: systemic additivity and spinal synergy. The antinociceptive interaction on the tail flick (TF) and hot plate (HP) tests between opioid analgesics and medetomidine after intravenous (iv) or intrathecal administration were examined by isobolographic analysis. ... | nervous system diseases |
Percutaneous fine-needle aspiration cytologic study of main pancreatic duct stenosis under pancreatographic guidance. When pancreatography shows a stenosis of the main pancreatic duct in patients with normal or inconclusive ultrasound and computed tomography, the exact nature of such stenosis is sometimes difficult to ... | neoplasms |
Rapid eye movement sleep deprivation as a probe in elderly subjects. The effects of a 2-night rapid eye movement (REM) sleep deprivation (RSD) procedure on electroencephalographic sleep and mood were examined in 15 healthy elderly control subjects, 14 elderly patients with endogenous depression, and 15 patients with pr... | nervous system diseases |
Cortical asymmetry of REM sleep EEG following unilateral pontine hemorrhage. A 24-year-old woman with a left pontine hematoma showed marked asymmetry in the EEG of REM sleep, suggesting that a unilateral pontine lesion is sufficient to disrupt normal REM sleep EEG in the ipsilateral hemisphere. Other REM sleep characte... | general pathological conditions |
Presence of identical mitochondrial proteins in unstimulated constitutive steroid-producing R2C rat Leydig tumor and stimulated nonconstitutive steroid-producing MA-10 mouse Leydig tumor cells. The acute regulation of steroidogenesis in steroidogenic tissues requires de novo protein synthesis. It is believed that these... | neoplasms |
Stress and sudden death. The case of the long QT syndrome. The idiopathic long QT syndrome (LQTS) represents a unique clinical example of stress-related sudden cardiac death. LQTS is characterized by the association of several distinctive electrocardiographic features, among which prolongation of the QT interval is the... | cardiovascular diseases |
Intraocular pressure and the rate of visual field loss in chronic open-angle glaucoma. We measured the rate of change of visual field threshold values over time (mean follow-up, 44.9 +/- 17.4 months) by trend analysis in 40 eyes of 40 patients with chronic open-angle glaucoma. Twenty-eight eyes had stable visual fields... | general pathological conditions |
Adenocarcinomas of the colon and rectum in persons under 40 years old. A population-based study. Data collected by nine population-based tumor registries participating in the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute were analyzed to characterize the epidemiology of noncarcino... | neoplasms |
Multiple breakpoint method for measuring effect of antibiotics on endocarditis strains of streptococci. The activity of penicillin alone and combined with aminoglycoside on endocarditis strains of streptococci was examined. Good assay reproducibility was obtained by the use of logarithmic phase cultures standardised by... | cardiovascular diseases |
Coronary artery fistula formation secondary to permanent pacemaker placement. We present the findings in two patients who apparently developed a coronary artery fistula as a complication of an endocardial pacing electrode. This complication may actually be occurring more frequently than recognized because the patient m... | cardiovascular diseases |
Structure and distribution of an Alu-type deletion mutation in Sandhoff disease. Sandhoff disease is a recessively inherited lysosomal storage disease resulting from a deficiency of beta-hexosaminidase activity. The enzyme occurs in two major forms, beta-hexosaminidase A, composed of an alpha- and beta-subunit and beta... | general pathological conditions |
Enlarged cisterna magna and the Dandy-Walker malformation: factors associated with chromosome abnormalities. Thirty-three fetuses with an enlarged cisterna magna (10 mm or more) were evaluated to determine factors that might be associated with an underlying chromosome abnormality. Eighteen fetuses (55%) proved to have ... | general pathological conditions |
MIC2 is a specific marker for Ewing's sarcoma and peripheral primitive neuroectodermal tumors. Evidence for a common histogenesis of Ewing's sarcoma and peripheral primitive neuroectodermal tumors from MIC2 expression and specific chromosome aberration. This study reports on the specific expression of the MIC2 gene, a ... | neoplasms |
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