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Radiographic identification by mastoid sinus and arterial pattern. A skull and some incomplete postcranial remains were discovered in two searches over a two-month period near Santa Fe, New Mexico. The discoveries could be demonstrated to be from the same person, and the remains were shown to be consistent with a speci... | general pathological conditions |
Physician practice for cardiovascular disease risk-factor reduction in six upper Midwestern communities. Preventive practice for coronary heart disease risk is increasingly accepted in the medical community. To determine the extent and characteristics of treatment advice for high blood pressure, blood cholesterol, and ... | cardiovascular diseases |
Short-term effect of hepatic arterial versus portal venous reperfusion on energy levels of liver tissue. The hepatic artery and the portal vein blood vary in flow, oxygenation, and hormonal content. It was uncertain which blood supply has a greater effect on the recuperative process of the hepatocytes in the ischemic l... | cardiovascular diseases |
Lower respiratory tract infections. Although lower respiratory tract infections are frequently diagnosed in a primary care setting, they are still associated with a significant morbidity and mortality, which warrants a careful approach to treatment. Knowledge of the most common cause based on the age of the patient, lo... | general pathological conditions |
Mycobacterium paratuberculosis and Crohn's disease. The possible aetiological role of Mycobacterium paratuberculosis in Crohn's disease was investigated. The immunological response was studied using an enzyme-linked immunosorbent assay (ELISA), Western blotting, and immunocytochemistry. The antibody response to two pro... | digestive system diseases |
Effects of aerobic exercise training on symptomatic women with mitral valve prolapse. The effects of a 12-week aerobic exercise training protocol on 32 symptomatic women with mitral valve prolapse were studied. Subjects were randomly assigned to control or exercise groups. Exercise subjects completed a 12-week (3 times... | general pathological conditions |
Is preoperative ultrasound cancer survey necessary in patients with normal liver function tests? Abdominal ultrasound examination is so easy that it may be overused. To reduce medical costs, we investigated whether preoperative ultrasonic abdominal survey was necessary for oncologic patients with normal liver function ... | neoplasms |
Genetics of NIDDM. This brief review discusses the current level of understanding of the role of genetic defects in the etiology of non-insulin-dependent diabetes mellitus (NIDDM) and the use of molecular-genetic methods for this study. Evidence for genetic susceptibility is strong, and defects in both insulin producti... | general pathological conditions |
Reduction of myocardial reperfusion injury by intravenous adenosine administered during the early reperfusion period. Adenosine influences the function of several cell types thought to be involved in the pathogenesis of myocardial reperfusion injury. We have previously demonstrated that intracoronary administration of ... | cardiovascular diseases |
Hormonal and enzymatic parameters of hepatic regeneration in patients undergoing major liver resections. Thirteen patients who underwent 40% to 80% removal of their livers had blood samples drawn initially and daily on postoperative days 1 to 7. The enzyme marker of heightened polyamine metabolism, ornithine decarboxyl... | neoplasms |
Intraventricular diamorphine via an Ommaya shunt for intractable cancer pain. We describe two patients in whom diamorphine was administered into the intraventricular space via an Ommaya reservoir, producing excellent pain relief. The use of this technique for long term administration of analgesia is reviewed. | general pathological conditions |
Propagation of deep venous thrombosis identified by duplex ultrasonography. To investigate the efficacy of anticoagulation in preventing continuing thrombosis, we prospectively evaluated 24 patients with acute deep venous thrombosis using duplex ultrasonography. All patients were hospitalized with conclusive ultrasonic... | cardiovascular diseases |
Extraoral application of osseointegrated implants. The use of osseointegrated implants to provide support for craniofacial prostheses has provided the clinician with another approach to the treatment of complex craniofacial reconstructive problems. The surgical technique is reviewed and the Mayo Clinic experience is pr... | neoplasms |
Differences in the membrane interaction of scrapie amyloid precursor proteins in normal and scrapie- or Creutzfeldt-Jakob disease-infected brains. The membrane interaction and hydrophobicity of the normal (PrPC) and infectious isoform (PrPSc/CJD) of scrapie and Creutzfeldt-Jakob disease amyloid precursor proteins was s... | nervous system diseases |
Active vs passive rhythms as an explanation of bigeminal rhythm with similar P waves. We describe the criteria for differential diagnosis between 3:2 sinoatrial block from atrial bigeminy due to an ectopic focus in the sinus or parasinus zone. In the 3:2 sinoatrial block the RR interval of the basic rhythm is similar t... | general pathological conditions |
Late onset adrenal hyperplasia: mutation at codon 282 of the functional 21-hydroxylase gene is not ubiquitous. Ten patients affected with 21-hydroxylase (21-OH) deficient late-onset adrenal hyperplasia were studied to determine the prevalence of a mutation at codon 281 of the functional 21-OH gene (CYP21B) that results... | general pathological conditions |
Perinatal infection of human T-lymphotropic virus type I, the etiologic virus of adult T-cell leukemia/lymphoma. DNA amplification of specific human T-lymphotropic virus type I sequences. A gene amplification technique, polymerase chain reaction, was used to detect human T-lymphotropic virus type I (HTLV-I), the etiolo... | neoplasms |
Incidence of adverse events and negligence in hospitalized patients. Results of the Harvard Medical Practice Study I BACKGROUND. As part of an interdisciplinary study of medical injury and malpractice litigation, we estimated the incidence of adverse events, defined as injuries caused by medical management, and of the ... | general pathological conditions |
Coagulation-fibrinolysis abnormalities in acute and chronic phases of cerebral thrombosis and embolism. We assayed plasma concentrations of fibrinogen, fibrinopeptide A, plasmin-alpha 2 plasmin inhibitor complex, D dimer, and antithrombin III activity in 40 patients with cerebral thrombosis and nine patients with cereb... | general pathological conditions |
Paratope- and framework-related cross-reactive idiotopes on anti-acetylcholine receptor antibodies. Cross-reactive idiotopes are a possible target for therapeutical interventions in autoimmune diseases. To investigate their role in the pathogenesis of experimental autoimmune myasthenia gravis (EAMG) we analyzed the Id ... | nervous system diseases |
Periventricular hyperintensity detected by magnetic resonance imaging in infancy. Twenty-one infants younger than 12 months of age were diagnosed as having periventricular hyperintensity (PVH) on T2-weighted magnetic resonance imaging. Ten infants had experienced neonatal asphyxia, 6 intracranial hemorrhage, 2 bacteria... | general pathological conditions |
Reconstruction of mandibular defects in irradiated patients. In this prospective study, mandibular reconstruction using titanium plates was evaluated in 31 patients treated between July 1988 and January 1990. Sixteen patients had prior surgery; 13 had prior radiotherapy. In 11 patients, prior radiation and surgery had ... | neoplasms |
Two discharge patterns of carotid body chemoreceptors in the goat. Twenty-nine single carotid body chemoreceptor units recorded during normocapnic normoxia from 20 anesthetized goats were classified into two groups by discharge pattern. Thirteen fibers, which had interspike interval distributions with a prominent peak ... | general pathological conditions |
Severe hemorrhagic radiation proctitis advancing to gradual cessation with hyperbaric oxygen. We report a case of a male patient suffering from a severe hemorrhagic radiation proctitis which gradually ceased with hyperbaric oxygen. We discuss the mechanisms of chronic radiation injury and the effect of the hyperbaric o... | digestive system diseases |
Critical aortic stenosis in early infancy. Anatomic and echocardiographic substrates of successful open valvotomy. To establish noninvasive criteria by which to manage infants with critical aortic stenosis, we examined 20 heart specimens from infants under 3 months of age and reviewed the clinical course and real time ... | cardiovascular diseases |
Kenneth McKenzie, Harvey Cushing, and the early neurosurgical treatment of spasmodic torticollis. In 1923, Dr. Kenneth McKenzie trained at the Peter Bent Brigham Hospital under Dr. Harvey Cushing. At that time, a patient with spasmodic torticollis came to Cushing and was treated with an innovative operation for this di... | nervous system diseases |
Crohn's disease of the lung Two years after developing colonic Crohn's disease, a 17 year old boy presented with focal pulmonary consolidation. A lung biopsy specimen showed areas of non-caseating epithelioid granuloma. Although some respiratory abnormalities appear to be associated with inflammatory bowel disease, gra... | digestive system diseases |
Effect of bleomycin on hematoporphyrin derivative phototherapy of solid tumors. Hematoporphyrin derivative phototherapy (HpD-PT) has been successfully used to localize and treat superficial squamous cell cancers. Bleomycin sulfate is a glycopeptide antibiotic that has antineoplastic properties against squamous cell can... | general pathological conditions |
Sacral plexus injury after radiotherapy for carcinoma of cervix. A 42-year-old woman developed lower extremity weakness and sensory loss 1 year after external and intracavitary radiotherapy for Stage IB carcinoma of cervix. She has been followed for 5 years posttreatment, and the neurologic abnormalities have persisted... | neoplasms |
Role of upper gastrointestinal investigations in a screening study for colorectal neoplasia. Should patients with positive faecal occult blood screening tests who are free of colorectal neoplasia undergo upper gastrointestinal investigation? Altogether 16,985 faecal occult blood tests were completed in a group of 18,81... | neoplasms |
The bone marrow in human immunodeficiency virus (HIV)-related disease. Morphology and clinical correlation. To determine the true incidence of abnormalities in bone marrow specimens from patients infected with human immunodeficiency virus (HIV) and the clinical significance of these abnormalities regarding their cause ... | nervous system diseases |
Treatment of hepatolithiasis: improvement of result by a systematic approach. In previous decades the result of treatment of hepatolithiasis has been unsatisfactory. The incidence of residual stones after surgery might reach 77%. In the past 6 years we adopted a systematic approach comprised of accurate delineation of ... | general pathological conditions |
Patterns of neuropsychological impairment after severe blunt head injury. A consecutive series of 100 subjects with severe blunt head injuries was followed up 6 years after trauma. Neuropsychological test performances of 82 subjects and of a noninjured control group were analyzed by two principal components analyses (P... | nervous system diseases |
Teflon versus thyroplasty versus nerve transfer: a comparison. Surgical rehabilitation of the paralyzed larynx is currently performed by Teflon injection, thyroplasty, and reinnervation techniques. Proponents of the two newer techniques maintain that they are preferred to Teflon injection because superior phonatory qua... | general pathological conditions |
Metabolism of human gliomas: assessment with H-1 MR spectroscopy and F-18 fluorodeoxyglucose PET Localized hydrogen-1 magnetic resonance (MR) spectroscopy and fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) were employed to obtain metabolic information from intracranial gliomas. Advantages and d... | neoplasms |
Minor papilla cannulation and dorsal ductography in pancreas divisum. Until recently, pancreas divisum represented a major technical barrier to a complete evaluation of pancreatic ductal anatomy. Technical refinements have now made it possible to achieve minor papilla cannulation and dorsal ductography in more than 90%... | digestive system diseases |
Abnormal growth patterns and adult short stature in 115 long-term survivors of childhood leukemia. Significant growth retardation was found in 115 survivors of childhood acute lymphoblastic leukemia (ALL) who had completed their growth. These children were diagnosed before 12 years of age and treated on four protocols ... | neoplasms |
Eosinophilic ascites due to hyperinfection with Strongyloides stercoralis. We report the case of a patient with cryptogenic cirrhosis, new onset ascites, and hyperinfection with Strongyloides stercoralis who had significant eosinophilia of the peritoneal fluid. The eosinophilia resolved with treatment of the S. stercor... | general pathological conditions |
Fistulas between the aorta and tracheobronchial tree. Aortobronchial fistula is a rare condition that is invariably fatal if not diagnosed and surgically treated. With appropriate surgical intervention, survival rates greater than 70% can be achieved. A review of the literature and an illustrative case report are prese... | cardiovascular diseases |
Functional results of facial nerve suture after removal of acoustic neurinoma: analysis of 25 cases. The facial nerve is sometimes severed during the removal of acoustic neurinomas, either intentionally to ensure complete removal, or unintentionally because of difficulties in identification. In such cases we have, if p... | neoplasms |
Isolated erythroid hypoplasia and renal insufficiency induced by long-term griseofulvin therapy. We describe a patient with hematuria, pyuria, eosinophiluria, decreased renal function, and severe anemia that developed while she was receiving chronic therapy with griseofulvin for onychomycosis. We offer evidence that gr... | general pathological conditions |
Optimal wound closure after tethered cord correction. Technical note. A technique of wound closure following tethered cord correction is presented that significantly reduces the incidence of cerebrospinal fluid collections in the subcutaneous space. In over 60 cases, the described method of fascia and skin closure has ... | nervous system diseases |
Congenital midline nasal masses: diagnosis and management. Congenital midline nasal masses (CMNMs) are rare lesions most commonly caused by dermoids, hemangiomas, nasal gliomas or encephaloceles. We report a case of nasal glioma and discuss the embryologic development, evaluation, and management of such CMNMs. | neoplasms |
Paediatric urolithiasis in Greece. A group of 44 patients, aged from 10 months to 14 years, underwent surgery for urinary calculi over a 7-year period (1982-1989). Eleven patients had bilateral or multiple calculi (total number of stones = 55, 20 of which were staghorn). Metabolic disorders (n = 25) and Proteus urinary... | general pathological conditions |
Treatment of Wegener's granulomatosis with intermittent high-dose intravenous cyclophosphamide PURPOSE: Concerns regarding the long-term toxicity of daily cyclophosphamide (CP) therapy for the systemic vasculitides have led us to evaluate alternative approaches to treatment in an attempt to achieve comparable efficacy ... | digestive system diseases |
Maintenance and relapse after weight loss in women: behavioral aspects. Obese women who regained weight after successful weight reduction (relapsers, n = 44); formerly obese, average-weight women who maintained weight loss (maintainers, n = 30); and women who had always remained at the same average, nonobese weight (co... | general pathological conditions |
Corticosteroids for acute, severe asthma. Corticosteroids have been used in the therapy of acute, severe asthma since the early 1950s. Numerous randomized, double-blind, placebo-controlled trials in adults and children have proven corticosteroids to be efficacious. Only the results from less rigorously designed trials ... | general pathological conditions |
Provision of gastrointestinal endoscopy and related services for a district general hospital. Working Party of the Clinical Services Committee of the British Society of Gastroenterology. (1) The number of endoscopic examinations performed is rising. Epidemiological data and the workload of well developed units show tha... | digestive system diseases |
Cognitive deficits in children: adaptive behavior and treatment techniques. Impaired cognitive functioning impedes the development of age-appropriate adaptive behavior, thus adding to the burdens of many children with epilepsy. Detailed neuropsychological assessment can identify the underlying ability-related impairmen... | nervous system diseases |
Anti-inflammatory effects of pentoxifylline in claudication. We measured neutrophil elastase/alpha 1 proteinase inhibitor complex (E/alpha) levels by ELISA in plasma samples drawn from 19 patients with claudication, before and at 1 and 2 months after initiation of pentoxifylline (PTF), 400 mg. p.o. tid. Plasma E/alpha ... | cardiovascular diseases |
Use of monoclonal antibody KP1 for identifying normal and neoplastic human mast cells. The monoclonal antibody KP1 (CD68) was used to stain normal and neoplastic monocytes and macrophages in routinely processed, paraffin wax embedded tissue: mast cells also exhibited strong, consistent cytoplasmic immunoreactivity. Lig... | neoplasms |
Effect of motilin on gastric emptying in patients with diabetic gastroparesis. OBJECTIVES: Because disturbances of gastric emptying are a serious complication in insulin-dependent diabetic subjects with regard to the maintenance of good metabolic control, we wanted to assess the effectiveness of motilin as a potential ... | general pathological conditions |
Genetics and biology of human ovarian teratomas. I. Cytogenetic analysis and mechanism of origin. One hundred and two benign, mature ovarian teratomas and two immature, malignant teratomas were karyotyped and scored for centromeric heteromorphisms as part of an ongoing project to determine the chromosomal karyotype and... | neoplasms |
Keratin subsets in spindle cell sarcomas. Keratins are widespread but synovial sarcoma contains a distinctive keratin polypeptide pattern and desmoplakins. The presence of individual keratin polypeptides and desmoplakins was immunohistochemically studied in 25 spindle cell sarcomas of different types using acetone-fixe... | nervous system diseases |
Stridor: intracranial pathology causing postextubation vocal cord paralysis. During an 18-month period in a pediatric intensive care unit, nine patients with vocal cord paralysis were identified using flexible bronchoscopy. When tracheally extubated, each child was found to have stridor. The children ranged in age from... | nervous system diseases |
Failure of internal fixation of displaced femoral neck fractures in rheumatoid patients. We reviewed the records and radiographs from 10 hospitals to identify 50 patients with rheumatoid arthritis (RA) who had sustained 52 femoral neck fractures. Most patients were female (88%), elderly (mean age 66 years) and had had ... | general pathological conditions |
Sjogren's syndrome and primary biliary cirrhosis: presence of autoantibodies to purified mitochondrial 2-OXO acid dehydrogenases. Sjogren's syndrome is well known for the presence of antibodies directed at specific nuclear antigens. However, the presence of antibodies reacting with a variety of other self antigens, inc... | digestive system diseases |
A clinicopathologic study of the eyes in familial adenomatous polyposis with extracolonic manifestations (Gardner's syndrome). The eyes of a 51-year-old woman with familial adenomatous polyposis and extracolonic manifestations (Gardner's syndrome) were obtained postmortem and studied by light microscopy and by transmis... | digestive system diseases |
Assessment of dilation methods in achalasia: large diameter mercury bougienage followed by pneumatic dilation as needed. In a retrospective study, 33 achalasia patients were treated with dilation therapy using large diameter mercury bougienage (mean, 56 French) and/or pneumatic balloon dilation. Mean follow-up time was... | general pathological conditions |
Xeroderma pigmentosum: review and report of a case. Xeroderma pigmentosum is a rare inherited dermatosis that provides insight into the basic mechanism of carcinogenesis. It is a model disorder linking defective DNA repair with clinical abnormalities and neoplasia. UV light-induced damage to the skin begins early and r... | general pathological conditions |
Steroid anabolic drugs and arterial complications in an athlete--a case history. Serious side effects and complications have been attributed to anabolic and androgenic steroids when used for medical reasons or when taken in sports in hopes of increasing strength and, hence, performance. The author presents a case of an... | cardiovascular diseases |
Malnutrition and carbohydrate malabsorption in children with vertically transmitted human immunodeficiency virus 1 infection. The nutritional needs of children with human immunodeficiency virus infection are poorly understood. Twenty-eight children with vertically transmitted human immunodeficiency virus infection were... | general pathological conditions |
Medicinal leeches: once again at the forefront of medicine. Medical grade leeches have recently been used in the management of acute problems relative to venous congestion in patients with traumatic injuries and surgical problems. Specific cases, especially in the realm of reconstructive microsurgery, have demonstrated... | cardiovascular diseases |
Hot spots for growth hormone gene deletions in homologous regions outside of Alu repeats. Familial growth hormone deficiency type 1A is an autosomal recessive disease caused by deletion of both growth hormone-1 (GH1) alleles. Ten patients from heterogeneous geographic origins showed differences in restriction fragment ... | general pathological conditions |
Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. Multiple sclerosis (MS) brain tissue, spleen, and PBMC were studied using immunocytochemistry and FACS for immunoreactivity for lymphotoxin (LT) and TNF. Both cytokines were identified in acute and chronic active MS lesions but were ... | general pathological conditions |
Cerebrospinal fluid fistula and endoscopic sinus surgery. Seven cases of cerebrospinal fluid fistulae occurring as a result of endoscopic sinus surgery in a total of 800 ethmoidectomies are discussed, along with 1 case referred for consultation. One cerebrospinal fluid fistula was intrasphenoid, 4 were posterior ethmoi... | general pathological conditions |
Beta-adrenergic effects on carbohydrate metabolism in the unweighted rat soleus muscle. The effects of insulin on carbohydrate metabolism in atrophied rat soleus muscle are increased after unweighting by tail-cast suspension. This work has been extended by testing the effect of unweighting on the response of carbohydra... | general pathological conditions |
Stunned myocardium and myocardial collagen damage: differential effects of single and repeated occlusions. It has been suggested that collagen loss and damage is responsible for the dysfunction seen in stunned myocardium. To test this hypothesis we compared collagen in canine hearts stunned by repeated occlusion with c... | cardiovascular diseases |
Surgical treatment of endomyocardial fibrosis: a new approach. Endomyocardial fibrosis has been treated surgically for many years. For complete removal of fibrosis from both ventricles by the classic technique, each atrioventricular (AV) valve was removed and replaced with a prosthesis. Relapse of endomyocardial fibros... | cardiovascular diseases |
Myocardial perfusion imaging with technetium-99m sestamibi SPECT in the evaluation of coronary artery disease. Technetium-99m (Tc-99m) sestamibi is a new myocardial perfusion imaging agent that offers significant advantages over thallium-201 (Tl-201) for myocardial perfusion imaging. The results of the current clinical... | cardiovascular diseases |
Angioscopic coronary macromorphology in patients with acute coronary disorders. To investigate the pathogenesis of acute coronary disorders and to clarify what type of plaque precedes these disorders, percutaneous transluminal coronary angioscopy, by means of a new angioscope, was carried out during catheterisation in ... | general pathological conditions |
Incisional parapubic hernias. A parapubic hernia, distinct from other lower abdominal wall hernias, is identified as a particular type of incisional hernia. This hernia results from the disruption of the musculotendinous elements of the abdominal wall as they insert into the pubis. This disruption is brought about by e... | digestive system diseases |
Tissue-specific transformation by epidermal growth factor receptor: a single point mutation within the ATP-binding pocket of the erbB product increases its intrinsic kinase activity and activates its sarcomagenic potential. Avian c-erbB is activated to a leukemia oncogene following truncation of its amino-terminal, lig... | general pathological conditions |
Short-term changes in renal function, blood pressure, and electrolyte levels in patients receiving cyclosporine for dermatologic disorders. We compared the changes in renal function, blood pressure (BP), and concentrations of serum potassium, magnesium, and urate (uric acid) in two groups of patients not given transpla... | cardiovascular diseases |
Complications of the pectoralis major myocutaneous flap in head and neck reconstruction. A retrospective review of the complications in 211 patients undergoing pectoralis major myocutaneous flap reconstruction is presented. The flap was used for mucosal lining of the oral cavity or oropharynx in 109 patients, for phary... | neoplasms |
Pyogenic hepatic abscess. Presented is a case of spontaneous pyogenic hepatic abscess in a previously healthy young man without associated risk factors. This disease entity has a low incidence, however, it is associated with significant morbidity and mortality if diagnosis and treatment are delayed. | general pathological conditions |
Delayed chest wall pain due to sternal wire sutures. This report describes 18 patients with disabling chest wall pain due to one or more sternal wire sutures. The pain occurred from 2 to 84 months after a median sternotomy. The pain was described either as sharp and stabbing or as a deep-seated ache. The involved wires... | general pathological conditions |
Unusual cause of 'piriformis muscle syndrome'. The piriformis muscle syndrome is a controversial "clinical" syndrome primarily characterized by signs and symptoms of sciatic nerve compression at the region of the piriformis muscle as it passes through the greater sciatic notch. The syndrome is often referred to; howeve... | general pathological conditions |
Trisomy 13: a new recurring chromosome abnormality in acute leukemia. A new recurring chromosome abnormality was identified in 8 of 621 consecutive successfully karyotyped adults with de novo acute leukemia. These eight patients had trisomy 13 as the sole cytogenetic abnormality. On central morphologic review, five cas... | neoplasms |
Study of preneoplastic changes of liver cells by immunohistochemical and molecular hybridization techniques. The status of hepatitis B virus DNA was investigated by in situ hybridization in multifocal areas of a noncancerous hepatitis B virus-associated cirrhosis. This liver exhibited a marked degree of dysplasia and a... | general pathological conditions |
Possible mechanisms of abnormal norepinephrine sensitivity and reactivity of resistance vessels and the development of hypertension in spontaneously hypertensive rats. A hypothesis. This study examined structural and functional changes of mesenteric resistance vessels in early, developing, and established stages of hyp... | cardiovascular diseases |
Very low birth weight children: behavior problems and school difficulty in a national sample We addressed three questions concerning the behavioral and academic status of low and very low birth weight infants through a secondary analysis of the 1981 National Health Interview Survey--Child Health Supplement: (1) in chil... | nervous system diseases |
Influence of chromosomal integration on glucocorticoid-regulated transcription of growth-stimulating papillomavirus genes E6 and E7 in cervical carcinoma cells. In most cervical carcinoma cells the E6 and E7 genes of specific human papillomaviruses are transcribed from viral sequences integrated into host cell chromoso... | neoplasms |
A randomized clinical trial to compare two different approaches in women with chronic pelvic pain. One hundred six patients with chronic pelvic pain were randomly allocated to one of two treatment groups. In the standard-approach group, organic causes of pelvic pain were excluded first and diagnostic laparoscopy was ro... | general pathological conditions |
Early and frequent detection of HBxAg and/or anti-HBx in hepatitis B virus infection. To clarify the significance of the X gene of hepatitis B virus, we have tested for anti-HBx in the serum and HBxAg in the liver at different stages of the natural history of hepatitis B virus infection. Sera were screened by enzyme-li... | digestive system diseases |
Glomerular binding and contractile response to angiotensin II in rats with chronic experimental cirrhosis of the liver. 1. The effects of angiotensin II on glomerular filtration rate and renal plasma flow were studied in surgically instrumented conscious control and cirrhotic rats. In addition, angiotensin II binding a... | general pathological conditions |
Ileal pouch-anal anastomosis. The Emory University experience. The ileal pouch-anal anastomosis has become a practical alternative to proctocolectomy for the treatment of ulcerative colitis and polyposis coli. To evaluate its success, the Emory University Affiliated Hospital experience from February 1984 to March 1989 ... | digestive system diseases |
Role of visceral afferent mechanisms in functional bowel disorders. This report analyzes the clinical and physiological evidence supporting a role for altered visceral afferent mechanisms in the pathogenesis of two functional bowel syndromes: noncardiac chest pain and the irritable bowel syndrome. Considerable recent e... | digestive system diseases |
Persistent primitive trigeminal artery-cavernous sinus fistulas: report of two cases. Two cases of persistent primitive trigeminal artery-cavernous sinus fistulas are presented. In one case, the fistula was treated by using a two-balloon tandem technique. This method was accomplished by introducing, inflating, and deta... | general pathological conditions |
Mayer-Rokitansky-Kuster-Hauser syndrome with splenosis. A case report. This is the first reported case of simultaneously occurring pelvic splenosis and Mayer-Rokitansky-Kuster-Hauser syndrome. No other congenital or anatomic abnormalities were observed in the patient, and she had no history of abdominal trauma or surge... | general pathological conditions |
Development of language in six hemispherectomized patients. The development of language skills in the isolated right hemisphere was investigated by comparing the performance of 3 left hemispherectomized with that of the 3 right hemispherectomized patients and three groups of control subjects on baseline clinical measur... | general pathological conditions |
A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway Major histocompatibility complex (MHC) class I molecules export peptides to the cell surface for surveillance by cytotoxic T lymphocytes. Intracellular peptide binding is critical for the proper ass... | general pathological conditions |
Two cases of spontaneous internal carotid artery occlusion due to giant intracranial carotid artery aneurysm. Although spontaneous thrombosis of a giant intracranial aneurysm is relatively common, occlusion of its parent artery is rare. We describe two recent patients in whom the parent artery spontaneously occluded. O... | cardiovascular diseases |
Role of angioplasty in myocardial infarction management strategies: a review. The role of angioplasty in acute myocardial infarction has been extensively studied in the past few years. Although angioplasty in some circumstances can be the primary reperfusion intervention, logistic problems and the excellent results of ... | general pathological conditions |
Ossified chronic subdural hematoma: case report. A case of ossified chronic subdural hematoma is presented in a 13-year-old male in whom the mass was surgically removed. His neurological deficits continued afterward but were less severe. | general pathological conditions |
Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage. In a double-blind randomized trial, the hemodynamic events following the administration of propranolol (n = 51) or a placebo (n = 51) were prospectively studied in cirrhotic patients with... | general pathological conditions |
5-year results of cisplatin and fluorouracil infusion in head and neck cancer. As part of the developmental process for the Head and Neck Intergroup trial of adjuvant chemotherapy for advanced resectable head and neck carcinoma, in 1981 the Radiation Therapy Oncology Group, Philadelphia, Pa, conducted two nonrandomized... | neoplasms |
Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus-induced demyelinating disease. IV. Identification of an immunodominant T cell determinant on the N-terminal end of the VP2 capsid protein in susceptible SJL/J mice. Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating dise... | nervous system diseases |
Human hepatic regenerative stimulator substance: partial purification and biological characterization of hepatic stimulator substance from human fetal liver cells. Current support or replacement therapies for fulminant acute hepatic failure are frequently very disappointing. In this study, human hepatic stimulator subs... | general pathological conditions |
Idiopathic bilateral spontaneous hyphemas. Spontaneous hyphemas are rare and usually associated with iris microhemangiomas or other vascular anomalies of the iris. In addition, various systemic problems can result in spontaneous hyphema. This is a case report of a bilateral spontaneous hyphema (recurrent in one eye), i... | general pathological conditions |
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