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Long-term adjuvant therapy of high-risk malignant melanoma with interferon alpha 2b. Fifty-three high-risk melanoma patients in stage I and 15 patients in stage II were treated after standard surgical intervention with adjuvant therapy with recombinant interferon alpha-2b (rIFN alpha 2b) therapy for a total period of 2...
neoplasms
Trabecular or Merkel's cell carcinoma. Two cases of trabecular cell carcinoma of the skin are presented. The clinical presentation and behavior, and the histologic findings, of the tumor are described. Surgical excision of the primary lesion with regional lymph node dissection, if indicated, is the treatment of choice....
neoplasms
Renal carcinoma in a solitary kidney. We studied the clinical and pathological features of 26 patients with renal carcinoma of a solitary kidney, including 6 treated at this hospital. Four patients had a contracted kidney and 22 had previously undergone nephrectomy. Partial nephrectomy was performed in 16 patients, enu...
general pathological conditions
Febrile infants less than eight weeks old. Predictors of infection. Febrile infants less than eight weeks old frequently are admitted and receive parenteral antibiotics for treatment of possible sepsis. The authors assess 52 infants less than eight weeks old with a rectal temperature of 38.1 degrees C or higher as havi...
general pathological conditions
Diphtheria-tetanus-pertussis vaccine and serious neurologic illness: an updated review of the epidemiologic evidence. A widespread impression that DTP vaccine does cause brain damage has been based first on historical precedent--smallpox and rabies vaccines were recognized as sometimes causing devastating neurologic il...
nervous system diseases
Expression of the human papillomavirus E7 oncogene during cell transformation is sufficient to induce susceptibility to lysis by activated macrophages. Human papillomaviruses (HPV), and in particular HPV type 16, are etiologic agents in the development of cervical cancer, which is the second most common form of cancer ...
general pathological conditions
Hypertension in Hispanics, Asians and Pacific-Islanders, and Native Americans. There is a paucity of information about hypertension and its risk factors, prevalence, morbidity, and mortality in many racial minorities in the United States. Most of the population groups discussed in this section are composed of several s...
cardiovascular diseases
Choledocholithiasis in Chinese immigrants with cholelithiasis. During the period from January 1987 to December 1989, admissions for biliary tract disease at the New York Infirmary--Beekman Downtown Hospital were split almost evenly between Chinese immigrants from southeast Asia and all other ethnic groups (Caucasian, H...
digestive system diseases
Magnetic resonance imaging of radiation optic neuropathy. Three patients with delayed radiation optic neuropathy after radiation therapy for parasellar neoplasms underwent magnetic resonance imaging. The affected optic nerves and chiasms showed enlargement and focal gadopentetate dimeglumine enhancement. The magnetic r...
neoplasms
Abdominal aortic aneurysm with perianeurysmal fibrosis: experience from 11 Swedish vascular centers. Case records of 2026 patients operated on because of abdominal aortic aneurysms from 11 Swedish Vascular Centers were reviewed and revealed 98 cases (4.8%) of inflammatory abdominal aortic aneurysm. Also included in thi...
cardiovascular diseases
What to do when an x-ray film suggests lung cancer. The chest film is one of the most common methods of detecting lung cancer, which often appears as solitary nodules or hilar masses. Once the diagnosis is established, the most effective treatment can be determined and staging of the tumor can be done. Surgical resecti...
neoplasms
Arteriographically determined occlusive disease within the hypogastric-cavernous bed in impotent patients following blunt perineal and pelvic trauma. To determine the presence, location and pattern of arterial occlusive disease within the hypogastric-cavernous arterial bed in impotent men following blunt perineal and p...
cardiovascular diseases
Large diameter expanded polytetrafluoroethylene grafts for infrarenal aortic aneurysm surgery. The performance of an expanded polytetrafluoroethylene (ePTFE) graft used for aortic aneurysm replacement was evaluated. ePTFE grafts were implanted in 241 patients undergoing infrarenal abdominal aortic aneurysm (AAA) repair...
cardiovascular diseases
The risk of lymph node metastasis in colorectal polyps with invasive adenocarcinoma. One hundred fifty-one patients with colorectal polyps containing invasive adenocarcinoma treated by resection were studied to determine the incidence of lymph node metastasis and whether lymph node metastasis was related to the depth o...
digestive system diseases
Sialosyl-Tn. A novel mucin antigen associated with prognosis in colorectal cancer patients. Colon cancers typically produce mucin. However, it is not known whether tumor mucin plays a biological role in cancer cell behavior. To address this issue, the expression of a mucin-associated antigen, sialosyl-Tn, was examined ...
neoplasms
Evaluation of methods for detecting venous reflux. Perspectives in venous insufficiency. Using 793 limbs with nonobstructive venous reflux, we evaluated a number of techniques used for the assessment of venous reflux. The venous Doppler examination was found to be a reliable screening tool with excellent sensitivity an...
cardiovascular diseases
Ischemic optic neuropathy. ION typically affects the older population with a sudden decrease in vision, altitudinal visual field loss, and a swollen optic nervehead. Systemic hypertension and diabetes mellitus are the most commonly associated medical problems. Occlusion of the posterior ciliary arterial blood supply to...
nervous system diseases
Failure of nutritional recovery after total gastrectomy. Malnutrition is reported to be an inevitable consequence of total gastrectomy, although there are few data to support this contention. Six patients of median age 63 years underwent total gastrectomy for malignancy. At follow-up (median 45 months, range 25-60 mont...
general pathological conditions
Perception and action in 'visual form agnosia'. A single case study of a patient with 'visual form agnosia' is presented. A severe visual recognition deficit was accompanied by impairments in discriminating shape, reflectance, and orientation, although visual acuity and colour vision, along with tactile recognition and...
nervous system diseases
Bladder function in the mentally retarded. A group of 21 mentally retarded patients with severe, long-standing urinary symptoms underwent urodynamical investigation. The most common abnormalities were detrusor areflexia and detrusor hyper-reflexia. Of 11 patients treated surgically, 10 derived marked benefit. Drugs wer...
nervous system diseases
Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma. Mutational inactivation of the retinoblastoma gene (RB) is found in all retinoblastomas and in a subset of other human neoplasms, including sarcomas of bone or soft tissue and carcinomas of lung or breast. Exogenous copies of wild...
general pathological conditions
Prophylaxis of uric acid stones with alternate day doses of alkaline potassium salts. Uric acid stone formation ordinarily is prevented by increases in the urinary pH after meals. This postprandial alkaline tide is lost in patients who make such calculi. Single dose, alternate day administration of an alkaline potassiu...
digestive system diseases
Late arterial hemorrhage secondary to a Greenfield filter requiring operative intervention. Retroperitoneal hematomas associated with Greenfield filters have been described and are generally characterized as clinically insignificant. We report a retroperitoneal hematoma that was associated with a Greenfield filter and ...
general pathological conditions
Thromboxane receptor blockade prevents pulmonary hypertension induced by heparin-protamine reactions in awake sheep We used competitive thromboxane A2-prostaglandin endoperoxide receptor blockade (SQ 30,741) as a probe to evaluate the role of thromboxane in ovine pulmonary vasoconstriction associated with protamine rev...
general pathological conditions
Doppler assessment of left ventricular filling pattern in silent ischemia in patients with Prinzmetal's angina. Spontaneous angina is an ideal condition in which to study left ventricular (LV) dysfunction induced by acute myocardial ischemia. In 6 patients with Prinzmetal's angina, LV diastolic function during 16 episo...
cardiovascular diseases
Selection of therapy for stage III breast cancer. Locally advanced breast cancer is a heterogenous group including both operable and inoperable lesions. Local surgery or radiation alone produces poor survival rates, indicating micrometastases at diagnosis. Systemic chemotherapy as part of multimodality regimens has inc...
neoplasms
Epilepsy. As surgical treatments for adult and pediatric forms of epilepsy have become more refined, methods for noninvasive localization of epileptogenic foci have become increasingly important. Detection of focal brain metabolic or flow abnormalities is now well recognized as an essential step in the presurgical eval...
nervous system diseases
The appearance of the piriformis muscle syndrome in computed tomography and magnetic resonance imaging. A case report and review of the literature. The piriformis syndrome (PS) is a controversial cause of hip pain because of the lack of objective findings to support the diagnosis. Computed tomography (CT) and magnetic ...
nervous system diseases
Age effects susceptibility to pulmonary barotrauma in rabbits. OBJECTIVE: We studied the effect of age on the development of pulmonary barotrauma after mechanical ventilation with high peak inspiratory pressures (PIP). DESIGN: Young (4 to 6 wk old) and adult rabbits were ventilated for 1 hr at PIPs of 15, 30, and eithe...
general pathological conditions
The cancer experience in the Framingham Heart Study cohort. The almost 40-year records of The Framingham Heart Study (FHS) cohort were reviewed to establish the cancer experience of this noninstitutionalized group of white subjects. Diagnoses were confirmed from pathology and laboratory reports and clinical notes. Age-...
cardiovascular diseases
Serum amylase in patients with renal insufficiency and renal failure. Results vary with regard to the upper limits of serum amylase seen in patients with renal failure, and very little has been reported with patients with renal insufficiency not yet requiring dialysis. To determine the level of serum amylase elevation ...
general pathological conditions
Trends in systolic blood pressure, 24-hour sodium excretion, and stroke mortality in the elderly in Belgium. Data from six surveys of systolic blood pressure conducted in Belgium between 1967 and 1986 were analyzed. The mean ages of the six groups of 3,328 subjects ranged from 70 to 81 years. The prevalence of systolic...
cardiovascular diseases
Sterol-dependence of gastric protective activity of unsaturated phospholipids. The major aim of this study was to investigate the gastric protective effect of unsaturated phospholipids and to determine the ability of neutral lipids to enhance this activity. We found that although a liposomal suspension of unsaturated p...
digestive system diseases
Colorectal adenocarcinoma in patients less than 40 years of age. From 1973 to 1985, 105 patients under 40 years of age were treated for colorectal adenocarcinoma at Roswell Park Cancer Institute. There were 51 males and 54 females. The mean age was 32 years. The majority of patients were treated for left colon or recta...
neoplasms
Transgenic mice susceptible to poliovirus. Poliovirus-sensitive transgenic mice were produced by introducing the human gene encoding cellular receptors for poliovirus into the mouse genome. Expression of the receptor mRNAs in tissues of the transgenic mice was analyzed by using RNA blot hybridization and the polymerase...
general pathological conditions
Leukemia initiated by hemopoietic stem cells expressing the v-abl oncogene. We report a mouse model with which to study leukemogenesis initiated by a specific genetic change introduced into a primary lymphoid-myeloid pluripotent stem cell. Fetal liver hemopoietic cells were infected with a high titer of helper-free Abe...
neoplasms
Response to diet and cholestyramine in a patient with sitosterolemia. In this report, an 11-year-old boy with diffuse tendinous and tuberous xanthomatosis and a plasma sterol concentration of 555 mg/dL, consisting primarily of cholesterol, is described. Three months after changing from an unrestricted diet to a cholest...
cardiovascular diseases
Gastric duplication cyst communicating with the pancreatic duct: a rare cause of recurrent abdominal pain. A 41-year-old woman with recurrent attacks of postprandial abdominal pain was found on endoscopic retrograde cholangiopancreatography and subsequent computed tomographic scan to have an enteric duplication within ...
digestive system diseases
Increased arterial adrenaline is related to pain in uncomplicated myocardial infarction. Plasma levels of catecholamines, beta-thromboglobulin (BTG) and arginine vasopressin (AVP), and degree of pain were examined in 22 patients with suspected uncomplicated myocardial infarction within 24 h following onset of chest pai...
cardiovascular diseases
Localization of malignant melanoma using monoclonal antibodies. Finding a screening test to evaluate patients with cancer for occult metastatic disease, as well as imaging all known disease, is a goal of research efforts. Twenty-nine evaluable patients with deeply invasive (stage I), regional nodal (stage II), or syste...
neoplasms
Aplasia cutis congenita and arteriovenous fistula. Case report and review. We describe a child with congenital aplasia cutis congenita of the scalp and an occult giant posterior fossa arteriovenous fistula. Previous case reports of central nervous system malformations associated with aplasia cutis congenita are reviewe...
general pathological conditions
Generation of human monoclonal antibodies against colon cancer. Lymphocytes from regional lymph nodes of patients with colon cancer were fused with a human lymphoblastoid cell line with or without in vitro immunization. The efficacy of these two protocols for the generation of human monoclonal antibodies against colon ...
neoplasms
Clinical analyses and short-term prognoses of neonates with subependymal cysts. Twenty-one neonates with subependymal cysts detected by neurosonography soon after birth were prospectively examined. The clinical and cranial sonographic findings were evaluated with respect to short-term prognosis. The prognosis was poor ...
neoplasms
Recurrent intracaval renal cell carcinoma: the role of intravascular ultrasonography. The presence of extension into the vena cava does not preclude curative resection for extensive renal cell carcinomas. However, preoperative assessment of (1) the proximal extent of the tumor and (2) the degree of adherence within the...
neoplasms
Bone marrow transplantation for myelodysplasia and secondary acute nonlymphoblastic leukemia. Twenty-three patients with primary myelodysplasia (MDS) or secondary myelodysplasia/acute nonlymphocytic leukemia (MDS/ANLL) were treated with allogeneic or syngeneic bone marrow transplantation (BMT). Only one patient was in ...
neoplasms
Epidermotropic eccrine porocarcinoma. Three cases of epidermotropic eccrine porocarcinoma are summarized and compared with reported cases. All patients had a long-standing tumor on a lower extremity that rapidly metastasized to the skin and proximal lymph nodes. The histologic picture was consistent with an intraepider...
cardiovascular diseases
Preperitoneal herniorrhaphy for the acutely incarcerated groin hernia. Elective preperitoneal or posterior repair for recurrent groin hernias and primary femoral hernias has been shown to be a technically advantageous approach. In addition to the ease of inguinal floor and femoral canal assessment, scar tissue from pri...
digestive system diseases
Ureteral triplication and ureterocele: report of 3 cases and review of the literature. We report 3 cases of ureterocele associated with ureteral triplication and review the literature. Ureteral triplication was type I in 2 patients and type II in 1. Diagnosis was established preoperatively in 2 cases and intraoperative...
general pathological conditions
Round fingerpad sign: an early sign of scleroderma. We describe a clinical skin sign in scleroderma termed round fingerpad sign. This term refers to disappearance of the peaked contour on fingerpads and replacement with a hemisphere-like fingertip contour; this change is especially apparent on the ring fingers. A posit...
general pathological conditions
Comparison of converting enzyme inhibitor and calcium channel blocker in hypertensive glomerular injury. The protective effect of converting enzyme inhibitors in experimental hypertensive glomerular injury is associated with decreased systemic arterial and glomerular capillary pressure. Although calcium channel blocker...
cardiovascular diseases
The use of a tourniquet when plating tibial fractures. Sixty closed fractures of the tibia were treated by open reduction and internal fixation with plates and screws. Half the operations were performed with a thigh tourniquet and half without. In the tourniquet group, there were six cases with erythema and induration ...
general pathological conditions
Effect of prior cancer chemotherapy on human tumor-specific cytotoxicity in vitro in response to immunopotentiating biologic response modifiers. Tumor-specific cytotoxicity was measured in fresh human biopsy specimens by a modification of the differential staining cytotoxicity assay. ImuVert, a cytokine inducer derived...
neoplasms
The elusive colonic malignancy. A need for definitive preoperative localization. Colonoscopy with biopsy is the standard of practice for the diagnosis of colonic malignancies. Unfortunately, the inability of endoscopy to obtain precise distance measurements from the anal verge can make localization of lesions at operat...
neoplasms
Fludarabine phosphate: a synthetic purine antimetabolite with significant activity against lymphoid malignancies. Fludarabine phosphate is the 2-fluoro, 5'-monophosphate derivative of vidarabine (ara-A) with the advantages of resistance to deamination by adenosine deaminase (ADA) and improved solubility. The mechanism ...
neoplasms
Cimetidine 800 mg twice daily for healing erosions and ulcers in gastroesophageal reflux disease. Although H2-receptor antagonists have been the mainstay of therapy for gastroesophageal reflux disease (GERD), none of these agents has been approved by the FDA as effective in healing lesions. Since proton pump inhibitors...
general pathological conditions
Lymphoma presenting as a popliteal mass in a patient with rheumatoid arthritis. A patient with HLA-B27 and rheumatoid factor positive rheumatoid arthritis presented with a painless swelling in his popliteal fossa. Clinical features were atypical for a Baker's cyst, and subsequent investigation showed this lesion to be ...
neoplasms
Misdiagnosis of the Zollinger-Ellison syndrome due to hyperlipidemia. Most authorities feel that diagnosis of the Zollinger-Ellison syndrome is established when the serum gastrin level is greater than 1000 pg/mL (1000 ng/L) in a patient with gastric acid hypersecretion and clinical manifestations consistent with the di...
neoplasms
Decreased operative risk of surgical treatment of mitral regurgitation with or without coronary artery disease. The consecutive 2 year experience with patients undergoing first-time surgery for mitral regurgitation with and without coronary artery disease was reviewed. From January 1988 to January 1990, 127 patients wi...
cardiovascular diseases
The effect of dopexamine HCl upon collateral perfusion of the acutely ischemic myocardium in anesthetized dogs. The effects of low-dose (10(-9) and 3 x 10(-9) mole/kg/min) infusions of dopexamine HCl, a new synthetic catecholamine with beta 2-adrenergic and DA1-dopaminergic agonostic actions, was tested in anesthetized...
cardiovascular diseases
Epidermolysis bullosa acquisita and associated symptomatic esophageal webs. Epidermolysis bullosa acquisita (EBA) is a well-characterized, subepidermal blistering disorder associated with autoimmunity to type VII collagen, which is the collagen localized to anchoring fibrils within the dermoepidermal junction of skin. ...
digestive system diseases
Supravalvar aortic stenosis: a complication of aortic valve surgery. After a patient had aortic valvotomy and aortotomy for the relief of valvar aortic stenosis supravalvar stenosis developed over the next six years.
general pathological conditions
Evaluation of the perforating veins of the lower extremity using high resolution duplex imaging. The purpose of this study was to evaluate duplex imaging as a means of assessing perforating veins in patients with longstanding venous stasis ulceration. Thirty patients with nonhealing venous stasis ulcers and twenty norm...
cardiovascular diseases
Respiratory input impedance in anesthetized paralyzed patients. Respiratory impedance (Zrs) was measured between 0.25 and 32 Hz in seven anesthetized and paralyzed patients by applying forced oscillation of low amplitude at the inlet of the endotracheal tube. Effective respiratory resistance (Rrs; in cmH2O.l-1.s) fell ...
general pathological conditions
White matter hyperintensities in dementia of Alzheimer's type and in healthy subjects without cerebrovascular risk factors. A magnetic resonance imaging study. T2-weighted (0.5 T) magnetic resonance images were used to study the prevalence of subcortical white matter hyperintensities (WMHIs) in 22 patients with dementi...
nervous system diseases
Creutzfeldt-Jakob disease from allogeneic dura: a review of risks and safety. Surgeons and the lay public have recently expressed concern over the safety of allogeneic dura as it relates to the transmission of Creutzfeldt-Jakob Disease. Indeed, two cases have resulted from use of tissue procured from a commercial agenc...
nervous system diseases
The effect of quinidine and mexiletine on the adaptation of ventricular refractoriness to an increase in rate. The purpose of this study was to determine the effects of quinidine and mexiletine on the adaptation of ventricular refractoriness to a change in heart rate. The ventricular effective refractory period was mea...
nervous system diseases
The long-term effectiveness of hysteroscopic treatment of menorrhagia and leiomyomas. One hundred fifty-six of 177 patients admitted to the St. Luke's/Roosevelt Hospital Center between November 1973 and November 1988 for hysteroscopic treatment of menorrhagia and/or uterine leiomyomas were followed for long-term compli...
general pathological conditions
Hemopump ventricular support for patients undergoing high risk coronary angioplasty. Prophylactic implantation of a Hemopump (Johnson and Johnson, Skillman, NJ) has been evaluated in nine patients selected for high risk coronary angioplasty. They were unstable patients, refractory to maximal pharmacology, with indicati...
cardiovascular diseases
The effects of epidural anesthesia on the Doppler velocimetry of umbilical and uterine arteries in normal and hypertensive patients during active term labor. To study the effects of epidural anesthesia on uterine and umbilical artery blood flow in preeclampsia, we observed 25 patients in active labor at 36 or more week...
cardiovascular diseases
Inflammatory abdominal aortic aneurysms. In a series of 517 operations for abdominal aortic aneurysm from 1971 to 1988 there were 45 cases (8.7%) with an inflammatory aneurysm with a typical thick glistening whitish fibrous layer. Almost two-third of the patients had rather severe chronic or acute progressive pain in t...
cardiovascular diseases
Mental activity, adrenergic modulation, and cardiac arrhythmias in patients with heart disease. All of the electrophysiological mechanisms of arrhythmias are sensitive to the influences of the autonomic nervous system, particularly to its adrenergic limb. Arrhythmogenic areas may also be dependent on the inhomogeneity ...
cardiovascular diseases
Facial bone fracture associated with carotid-cavernous sinus fistula. Out of 989 cases of facial bone fracture, ten patients had carotid-cavernous sinus fistulas (1.01%). Their ages ranged from 25 to 48 years. Seven were male and three female. Two of the ten patients had lower third, three patients had middle third, th...
nervous system diseases
Nephropathy in model combining genetic hypertension with experimental diabetes. Enalapril versus hydralazine and metoprolol therapy. We compared the effects of the angiotensin-converting enzyme inhibitor enalapril and a conventional antihypertensive regimen (hydralazine and metoprolol) on kidney function, albuminuria, ...
cardiovascular diseases
Endoscopic appearance and significance of functional lymphangiectasia of the duodenal mucosa. Intestinal lymphangiectasia is found in a wide variety of pathologic conditions. Functional lymphangiectasia has not been well characterized. We report 20 patients followed for 9 to 55 months (mean 30 months) after incidental ...
digestive system diseases
Postictal psychosis after partial complex seizures: a multiple case study. Bouts of unusually frequent partial complex seizures originating in the temporal lobe, that sometimes became secondarily generalized, induced psychotic episodes in 9 patients. In 7, the increase in seizures occurred at a time when antiepileptic ...
nervous system diseases
Popliteal artery aneurysms. Long-term follow-up of aneurysmal disease and results of surgical treatment. The natural history of aneurysmal disease was analyzed in 50 patients who were treated for 71 popliteal aneurysms. No patients were lost to follow-up (mean, 5.0 years). Initially, 25 popliteal aneurysms (25/71; 35%)...
cardiovascular diseases
Malnutrition and carbohydrate malabsorption in children with vertically transmitted human immunodeficiency virus 1 infection. The nutritional needs of children with human immunodeficiency virus infection are poorly understood. Twenty-eight children with vertically transmitted human immunodeficiency virus infection were...
digestive system diseases
Ogilvie's syndrome. Would you recognize it? Numerous conditions predispose to Ogilvie's syndrome, a process that mimics bowel obstruction. Characteristic radiographic findings of acute pseudo-obstruction include dilatation of the cecum and the remainder of the colon but not the small intestine. Treatment is individuali...
digestive system diseases
Second primary cancer following Hodgkin's disease: updated results of an Italian multicentric study. The risk of second primary cancer (SPC) was evaluated in 947 patients treated for Hodgkin's disease (HD) during the period January 1969 to December 1979. The median follow-up of this series was 10.5 years (range, 9 to 1...
neoplasms
Transtelephonic defibrillation. STUDY OBJECTIVES: This study was undertaken to assess the safety and reliability of a device for transtelephonic defibrillation. DESIGN: The transtelephonic system consists of a patient unit and a base station. The patient unit contains a monitor-defibrillator, electrode pads, microphone...
cardiovascular diseases
How selective is selective posterior rhizotomy? Although selective posterior rhizotomy has become an increasingly utilized surgical treatment for spasticity, the procedure is unstandardized and is performed differently at various medical centers. Most surgeons use some form of direct dorsal rootlet stimulation with int...
nervous system diseases
Importance of sampling method in DNA analysis of lung cancer. Lung carcinomas are characterised by considerable histological variation within the tumour. The possible effects of this morphological heterogeneity on the estimation of tumour ploidy were investigated. Multiple tissue blocks were systematically taken from 2...
general pathological conditions
Prognostic implications of DNA histogram, DNA content, and histologic changes of regional lymph nodes in patients with lung cancer. Forty-six cases of resected lung cancer, including 20 cases at Stages I and II and 26 cases at Stage III (N2), were subdivided into two groups: a good prognosis group with a longer surviva...
general pathological conditions
Hepatomuscular failure in septic catabolism: altered muscular response to plasma proteolytic factor in decreased hepatic mitochondrial redox potential. To estimate the contribution of muscle protein in whole-body protein catabolism, the muscular contribution index (MCI; urine 3-methylhistidine/urine total nitrogen) was...
general pathological conditions
Therapeutic embolization: enhanced radiolabeled monitoring. Radiolabeling of Ivalon (polyvinyl alcohol sponge) particles permits localization of injected particles during embolization through the use of a portable gamma camera and provides a means to prevent potentially fatal complications such as pulmonary embolizatio...
cardiovascular diseases
Accuracy of prospective two-dimensional/Doppler echocardiography in the assessment of reparative surgery. Between January 1987 and January 1989, all 129 patients (aged 11 days to 25 years, median 39 months) undergoing both an echocardiographic examination and cardiac catheterization after reparative surgery were prospe...
cardiovascular diseases
Surgical management of carcinoid heart disease Metastatic carcinoid tumor is often seen with flushing, diarrhea, and cardiac symptoms--the carcinoid syndrome. Cardiac failure is often associated with major morbidity and mortality in carcinoid disease. In this report, a case of successful cardiac valvar surgical interve...
neoplasms
Radiation-induced cranial nerve palsy: hypoglossal nerve and vocal cord palsies. Cranial nerve palsies are an unexpected complication of radiotherapy for head and neck tumours. We present a case of this radiation-induced cranial palsy. An 18-year-old female with nasopharyngeal carcinoma developed a right hypoglossal ne...
neoplasms
Serum enzyme alterations in chronic muscle disease. A biopsy-based diagnostic assessment. The results of interpretation of muscle biopsies were compared retrospectively to activities of serum enzymes and isoenzymes. A total of 137 patients seen at the Cleveland Clinic Foundation in 1986 and 1987 were included in this s...
general pathological conditions
Postcardiotomy mechanical circulatory support in the elderly. The role of mechanical circulatory support after cardiac operations in elderly patients is not clearly established. Between November 1985 and July 1989, 18 patients 65 years of age or older (mean age, 71 years; range, 65 to 82 years) were treated after cardi...
nervous system diseases
Abnormal epidermal changes after argon laser treatment. A 26-year-old woman with a congenital port-wine stain on the forehead was treated three times at 2-month intervals with an argon laser. Six months after the last treatment, moderate blanching and mild scaling confined to the treated area was observed. A biopsy spe...
neoplasms
Ultrasound-guided aspiration for transient synovitis of the hip. We reviewed 15 children with transient synovitis of the hip who had aspiration of an effusion under local anaesthesia with ultrasound guidance. There were no significant complications; aspiration was useful for diagnosis and gave considerable symptomatic ...
general pathological conditions
A nongastrin malignant ampullary tumor causing gastric acid and pepsin hypersecretion. A case report. We report a case of multiple duodenal ulcers with gastric hypersecretion due to a nongastrin secretagogue produced by a malignant tumor of the pancreas in a 78-year-old man. The case resembled a Zollinger-Ellison syndr...
digestive system diseases
Threshold perimetry in tilted disc syndrome. Twelve consecutive patients (17 eyes) with tilted disc syndrome underwent quantified visual field examination with the G1 Octopus program (Interzeag AG, Schlieren, Switzerland). Visual fields were abnormal in all cases. Although field loss was more pronounced in the superote...
general pathological conditions
Percutaneous coronary excimer laser-assisted balloon angioplasty: initial clinical and quantitative angiographic results in 50 patients. The initial clinical experience and quantitative angiographic results of percutaneous coronary excimer laser-assisted balloon angioplasty are described for 55 lesions in 50 patients. ...
cardiovascular diseases
Image cytophotometric DNA analysis of atypical hyperplasias and intraductal carcinomas of the breast. With the use of image analysis, DNA content was quantified on paraffin-embedded tissue sections of 25 atypical hyperplasias and 35 intraductal carcinomas of the breast by comparison of integrated gray levels of Feulgen...
neoplasms
Left ventricular mid-cavitary obstruction after balloon dilation in isolated aortic valve stenosis in children. A hyperdynamic left ventricle can lead to post-dilation mid-cavitary obstruction in the absence of any preballoon mid-cavitary obstruction in children with aortic valve stenosis. The purpose of this study was...
cardiovascular diseases
Generation of "soft x-rays" by using the free electron laser as a proposed means of diagnosing and treating breast cancer. The diagnosis and treatment of breast lesions may be markedly enhanced by the use of a unique new source of near-monochromatic x-rays. Concentric beams of near-monochromatic x-ray photons may be ge...
neoplasms
Effect of portasystemic shunts on subsequent transplantation of the liver. Portasystemic (PS) shunts have been regarded as a relative contraindication to hepatic transplantation (HT) because of the potential for increased technical difficulties during the transplant operation. We compared operative blood loss, morbidit...
digestive system diseases
Primary intramedullary nailing of open femoral shaft fractures. The cases of 60 patients with 63 open femoral fractures treated by primary reamed intramedullary nailing were retrospectively reviewed. Twenty-two were classified as Type I open fractures, 26 as Type II and 15 as Type III open fractures by Gustilo's classi...
general pathological conditions