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Omeprazole 20 mg three days a week and 10 mg daily in prevention of duodenal ulcer relapse. Double-blind comparative trial. In a double-blind, parallel-group clinical trial of 195 patients with duodenal ulcers who after a short-term study had relief of pain and healed ulcers proved endoscopically, 65 were randomized to...
digestive system diseases
Effects of anxiety on family members of patients with cardiac disease learning cardiopulmonary resuscitation. The effects of anxiety on learning cardiopulmonary resuscitation (CPR) by family members of patients with cardiac disease was examined. Family members of hospitalized patients (n = 17), family members of nonhos...
cardiovascular diseases
Risk monitoring of randomized trials in emergency medicine: experience of the Brain Resuscitation Clinical Trial II. Risk monitoring for the Brain Resuscitation Clinical Trial II, a multicenter, placebo-controlled trial to evaluate the efficacy of the calcium-entry blocker lidoflazine in the amelioration of brain damag...
cardiovascular diseases
Unsuspected syphilitic hepatitis in a patient with low-grade proteinuria and abnormal liver function A 25-year-old patient was found to have cholestatic liver enzyme abnormalities during assessment for asymptomatic low-grade proteinuria at the US Naval Hospital in Portsmouth, Virginia. These abnormalities persisted for...
digestive system diseases
The surgical treatment of atrial fibrillation. I. Summary of the current concepts of the mechanisms of atrial flutter and atrial fibrillation. Atrial fibrillation is a common arrhythmia that is frequently resistant to medical therapy and has no satisfactory surgical therapy. The development of an effective surgical pro...
general pathological conditions
Substance-P is present in a subset of thyrotrophs in the human pituitary. Substance-P immunoreactivity and tachykinin-like peptides are present in the pituitary gland of several mammalian species. In humans, however, the biochemical nature and cellular localization of pituitary substance-P has not been defined. We repo...
neoplasms
Meningitis in the neurosurgical patient. In the patient with a basilar skull fracture and CSF leak, the risk of meningitis is greatly increased. The diagnosis of both leak and infection can be obscured by the patient's other injuries, and requires aggressive investigation of symptoms that suggest infection. Although th...
general pathological conditions
Effects of theophylline, atenolol and their combination on myocardial ischemia in stable angina pectoris. The effects of theophylline (400 mg twice a day), atenolol (50 mg twice a day) and their combination on myocardial ischemia were studied in 9 patients with stable angina pectoris in a randomized, single-blind, trip...
cardiovascular diseases
Total left main coronary artery occlusion after aortic aneurysm repair and valve replacement. A 38-year-old woman with complete occlusion of the left main coronary artery secondary to cannulation during aortic valve replacement is presented. The clinical course was characterized by progressive left ventricular dysfunct...
cardiovascular diseases
Epidemiologic studies demonstrating increased morning incidence of sudden cardiac death. To determine if sudden cardiac death shows a circadian variation, the mortality records of the Massachusetts population and the Framingham Heart Study were analyzed. The Massachusetts mortality data analysis revealed an increased m...
general pathological conditions
Population aging patterns: the expansion of mortality. We used the hypothesis of mortality compression as a framework to examine patterns of mortality from 1962 to 1984. Data from national vital statistics records were used for analysis of the changing age at death for percentiles of the population. Data from the Socia...
general pathological conditions
Two cases of adult T-cell leukemia associated with acute pancreatitis due to hypercalcemia. We report two cases of adult T-cell leukemia associated with acute pancreatitis and hypercalcemia. After sudden onset of epigastralgia, acute pancreatitis and hypercalcemia were found in both patients. There were no diseases tha...
neoplasms
Education and epilepsy: assessment and remediation. Learning difficulties in children with epilepsy may be caused by brain damage and should be investigated. In many cases, however, seizures and/or electroencephalographic (EEG) findings are the only signs of pathology. Frequency and type of seizures may be determining ...
general pathological conditions
The neuroradiology of visual disturbances. The neuroradiology of visual deficits has advanced dramatically in recent years. Plain film evaluation of the orbit and face remains useful in the emergency room for the evaluation of trauma. High-resolution coronal CT remains the method of choice in the assessment of serious ...
neoplasms
Treatable abdominal pathologic conditions and unsuspected malignant neoplasms at autopsy in veterans who received mechanical ventilation. STUDY OBJECTIVE: To determine, in medical patients who received mechanical ventilation, the frequency and types of major unexpected diagnoses at autopsy that, if known before death, ...
neoplasms
Long-term follow-up of patients after transcatheter direct current ablation of the atrioventricular junction. The long-term follow-up study (41 +/- 23 months) of 47 patients undergoing direct current ablation because of drug-resistant supraventricular arrhythmias is reported. Significant early complications occurred in...
general pathological conditions
Therapy of persistent human papillomavirus disease with two different interferon species. Consensus interferon and interferon alfa-2a were used to treat patients with persistent human papillomavirus disease. Thirty-one patients were treated with either consensus interferon or a placebo (25 received active drug and 6 re...
general pathological conditions
Effects of vasopressin on portal pressure during hemorrhage from esophageal varices. Vasopressin is often used to treat variceal hemorrhage. However, its efficacy is uncertain, and its portal hemodynamic effects in this setting are unknown. Eleven patients with alcoholic liver disease and bleeding varices were given va...
digestive system diseases
Physician practices in the diagnosis of dementing disorders. Because there are both treatable and untreatable causes of dementia, the physician's ability to conduct (or refer a patient for) a differential diagnosis could have a profound effect on health outcomes for patients and on health care costs. This study was und...
nervous system diseases
High risk of recurrent stroke after discontinuance of five to twelve years of transfusion therapy in patients with sickle cell disease. Although long-term transfusion therapy is at least 90% effective in preventing recurrent strokes after an initial cerebrovascular accident in patients with sickle cell disease, it is u...
general pathological conditions
Benign and malignant nodules in cirrhotic livers: distinction based on blood supply. The blood supplies of nodular lesions associated with liver cirrhosis were analyzed in vivo with various imaging modalities. The portal blood supply was evaluated with computed tomography (CT) during arterial portography (CTAP); the ar...
digestive system diseases
Severe thrombocytopenia after paracetamol overdose. Two patients with severe thrombocytopenia after paracetamol overdose are described. The platelet count was lowest two days after the overdose. Neither leucopenia nor anaemia occurred.
digestive system diseases
Epidemiologic studies demonstrating increased morning incidence of sudden cardiac death. To determine if sudden cardiac death shows a circadian variation, the mortality records of the Massachusetts population and the Framingham Heart Study were analyzed. The Massachusetts mortality data analysis revealed an increased m...
cardiovascular diseases
Long-term follow-up of patients operated on for recurrent carotid stenosis. We reviewed our experience with 29 operations for recurrent carotid stenosis in 27 patients who underwent both their primary carotid endarterectomy and their reoperations at our institution. These 27 patients represent 4% of the 667 patients wh...
general pathological conditions
Equal parental origin of chromosome 22 losses in human sporadic meningioma: no evidence for genomic imprinting. Inactivation of tumor suppressor genes can occur either by mutation at the gene locus or by loss of part or all of the chromosome region containing the gene. The latter is most frequently detected by DNA mark...
neoplasms
Effect of long-term exercise on regional myocardial function and coronary collateral development after gradual coronary artery occlusion in pigs. The effect of myocardial ischemia, induced by long-term exercise, on regional myocardial function and coronary collateral development was examined in pigs after gradual occlu...
cardiovascular diseases
Diagnostic criteria for neuropsychiatric systemic lupus erythematosus: the results of a consensus meeting. The Ad Hoc Neuropsychiatric Lupus Workshop Group. Definitions and classifications proposed for the neuropsychiatric complications of systemic lupus erythematosus (NP-SLE) indicate a wide range of approaches taken ...
nervous system diseases
Severe aortic regurgitation as a late complication of temporal arteritis. Two patients with a remote history of pathologically documented giant cell arteritis developed severe regurgitation. The first patient developed severe aortic regurgitation five years after the pathologic documentation of giant cell arteritis of ...
cardiovascular diseases
The incidence of myocarditis in endomyocardial biopsy samples from patients with congestive heart failure. We present the combined experience of three Yugoslavian cardiovascular centers in the application of endomyocardial biopsy for the diagnosis of myocarditis in patients who present clinically with congestive heart ...
cardiovascular diseases
Aortic calcified plaques and cardiovascular disease (the Framingham Study). The relation between the presence of calcified plaques in the thoracic aorta, as detected on chest x-rays, and the development of cardiovascular disease is examined during 12 years of follow-up of the Framingham cohort (n = 5,209). The prevalen...
nervous system diseases
Reduction in hepatic venous pressure gradient as a consequence of volume contraction due to chronic administration of spironolactone in patients with cirrhosis and no ascites. The effect of plasma volume contraction induced by a 4-wk administration of spironolactone or furosemide on the hepatic venous pressure gradient...
digestive system diseases
Different prevalence and degree of nonspecific bronchial hyperreactivity between seasonal and perennial rhinitis. From the patients observed at our respiratory allergology service, we selected patients with rhinitis only, without any past or present respiratory symptoms, for our study. All these patients had normal pul...
general pathological conditions
Characteristics of biliary lipid metabolism after liver transplantation. Biliary lipid metabolism was studied after 10 liver transplantations with continuous drainage of bile. Within 3 wk after transplantation, the new liver produced bile with concentrations of biliary lipids in agreement with those reported for T-tube...
cardiovascular diseases
Pre-trigeminal neuralgia. Eighteen patients who subsequently developed typical trigeminal neuralgia experienced a prodromal pain termed "pre-trigeminal neuralgia." These patients described their prodromal pain as a toothache or sinusitis-like pain lasting up to several hours, sometimes triggered by jaw movements or by ...
nervous system diseases
Evaluating cervical cone biopsy specimens with frozen sections at hysterectomy. Frozen section evaluations of cervical cone biopsy specimens were performed at the time of hysterectomy to exclude invasive cervical cancer. During a two-year period we prospectively evaluated 43 cone biopsy specimens. We found all the diag...
neoplasms
Measurement and treatment in cerebral palsy: an argument for a new approach. This article describes the need for a shift in our therapeutic strategies for patients with cerebral palsy. Changes in functional abilities must be stressed in therapy. Coincident with this emphasis must be the development of functional assess...
nervous system diseases
Arterial mechanical properties in dilated cardiomyopathy. Aging and the response to nitroprusside. The effects of aging on arterial mechanical properties and the response to nitroprusside were examined in 25 patients with dilated cardiomyopathy. High-fidelity pressures were recorded with a multisensor catheter. Pulse w...
cardiovascular diseases
Isolated trigeminal sensory loss secondary to a distal anterior inferior cerebellar artery aneurysm: case report. A previously healthy 25-year-old woman suddenly developed right-sided facial numbness and a headache. The neurological examination was within normal limits with the exception of meningismus and right-sided ...
general pathological conditions
High NaCl diet enhances arterial baroreceptor reflex in NaCl-sensitive spontaneously hypertensive rats. Previous studies from our laboratory have shown that arterial baroreceptor reflex control of lumbar sympathetic nerve activity is blunted in the NaCl-sensitive spontaneously hypertensive rat (SHR-S) compared with eit...
cardiovascular diseases
The growing teratoma syndrome. Thirteen patients with metastatic non-seminomatous germ cell tumours and enlarging metastases consisting of teratoma differentiated only were identified. Patients were managed with surgical resection soon after the growing lesions were documented. Surgical morbidity was minimal and 12 pat...
neoplasms
The lateral approach for operative release of post-traumatic contracture of the elbow. A lateral approach was used to release a post-traumatic contracture of the elbow in seven patients, and the results were evaluated an average of thirty-eight months postoperatively. Extension improved from an average flexion contract...
general pathological conditions
Rhabdomyosarcoma of the ciliary body. Rhabdomyosarcoma is the most common malignant orbital tumor of childhood. It has twice been reported to arise within the globe from the iris. In addition, teratoid medulloepithelioma, a tumor arising from the ciliary epithelium, can contain a rhabdomyoblastic component, often in co...
neoplasms
Leukoaraiosis, intracerebral hemorrhage, and arterial hypertension. To investigate whether the observed association of leukoaraiosis with intracerebral hemorrhage is direct or mediated by risk factors, we compared 116 patients with intracerebral hemorrhage confirmed by computed tomography and 155 controls without intra...
cardiovascular diseases
Failure of Hancock pericardial xenografts: is prophylactic bioprosthetic replacement justified? The incidence of major valve-related complications was evaluated in a series of patients in whom the Hancock pericardial xenograft was used for aortic (AVR; n = 84), mitral (MVR; n = 17) and mitral-aortic (MAVR; n = 13) valv...
cardiovascular diseases
Elderly men with histories of heavy drinking: correlates and consequences. Recognition that the physical, psychological and social consequences of substance abuse may persist throughout the life span has led to increased study of the impact of lifetime drinking habits on the elderly. We examined the characteristics of ...
neoplasms
Botulinum toxin therapy. Botulinum toxin therapy has emerged as a treatment modality for a variety of spastic- or contracture-related muscle diseases. Its safety has been proven for long-term use in the treatment of benign essential blepharospasm, hemifacial spasm, and certain types of strabismus. Recent approval from ...
general pathological conditions
Cervicogenic headache: diagnostic criteria. Criteria for the diagnosis of cervicogenic headache are proposed, which include unilateral head pain, symptoms and signs of neck involvement, non-clustering episodic moderate pain originating in the neck then spreading to the head, and response to root or nerve blockade; plus...
nervous system diseases
Venous ulcers: pathophysiology and medical therapy. Venous ulcers may occur as a result of lower extremity calf pump failure, with ensuing edema, trapping of white blood cells and deposition of pericapillary fibrin. Acute, smaller lesions are easily treated with adequate compression and occlusive dressings. Larger, mor...
cardiovascular diseases
Unusual posterior retinal holes associated with high myopia in XYY syndrome. A 49-year-old XYY man was found to have high myopia OU with unusual multiple retinal atrophic holes located in the posterior pole, unrelated to a posterior staphyloma or any other myopic degenerative changes. Most of the retinal holes showed s...
general pathological conditions
The effect of age on treatment choice and survival in elderly breast cancer patients. To investigate the effect of age on treatment choice and survival in patients with breast cancer, data from the cancer registry of the Netherlands Cancer Institute (NKI, Amsterdam, The Netherlands) on 611 women have been analyzed. All...
neoplasms
Diagnosis of noninfective cardiac mass lesions by two-dimensional echocardiography. Comparison of the transthoracic and transesophageal approaches. This study was conducted in 46 patients with cardiac thrombi, 15 patients with atrial myxomas, and 32 patients with other cardiac or paracardiac tumors. Diagnoses were subs...
cardiovascular diseases
Myocardial infarction in the young adult. CAD in young male adults below the age of 40 years has generally been found to be associated with the usual risk factors associated with CAD. In a lesser number of young adults, MIs may be related to cocaine use. Sympathomimetic effects and increase in myocardial oxygen demand ...
cardiovascular diseases
Hypophosphatemia and renal tubular dysfunction in alcoholics. Are they related to liver function impairment? The study was designed to evaluate (a) the role of reduced renal phosphate reabsorptive capacity assessed as the ratio of maximum capacity for renal phosphate reabsorption (TmPO4) to glomerular filtration rate (...
digestive system diseases
Relationship between blood pressure, plasma insulin and triglyceride concentration, and insulin action in spontaneous hypertensive and Wistar-Kyoto rats. Previous results have shown that spontaneously hypertensive rats (SHR) are insulin resistant, hyperinsulinemic, and hypertriglyceridemic as compared to Wistar-Kyoto r...
cardiovascular diseases
Endoscopic management of postoperative biliary leaks: review of 77 cases and report of two cases with biloma formation. Biliary leaks are uncommon complications of abdominal surgery. Left untreated, they may result in significant morbidity and mortality. The traditional treatment has been surgical, but several authors ...
general pathological conditions
Limitations of electroencephalographic monitoring in the detection of cerebral ischemia accompanying carotid endarterectomy. An analysis was undertaken of 458 consecutive carotid endarterectomies performed over 6 years with the patient under general anesthesia and with electroencephalographic monitoring. Seventy patien...
nervous system diseases
Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake. Glutamate uptake into nerve and glial cells usually functions to keep the extracellular glutamate concentration low in the central nervous system. But one component of glutamate release from neurons is calcium-independent, su...
general pathological conditions
Calcium and contractile responses to phorbol esters and the calcium channel agonist, Bay K 8644, in arteries from hypertensive rats. This study examined the calcium dependency of contractions in arteries from rats made hypertensive by aortic coarctation and in rats with genetic hypertensive (stroke-prone spontaneously ...
cardiovascular diseases
Hyaluronan in pleural effusions and in serum. It has been suggested that a high level of hyaluronan (hyaluronic acid, HYA) in pleural fluid is an indicator of malignant mesothelioma. In 78 consecutive patients with pleural effusion of various causes the HYA concentration was measured in pleural fluid samples and in ser...
general pathological conditions
Reliability of death certificate diagnoses. Consistency between death certificates and clinical records from 5 general hospitals in Kuwait was studied for 470 deaths with the following underlying or associated causes: hypertensive (HYP), ischaemic heart diseases (IHD), cerebrovascular diseases (CVD) and diabetes mellit...
cardiovascular diseases
Increased platelet membrane sodium-proton exchange rate in spontaneously hypertensive rats. It has been proposed that increased Na-H exchange activity is involved in the pathophysiology of genetic hypertension. We studied platelets of spontaneously hypertensive rats (SHR), normotensive Wistar-Kyoto (WKY), and domestic ...
cardiovascular diseases
The vascularized fibula graft in mandibular reconstruction. The use of a vascularized graft from the fibula for mandibular reconstruction is presented. The great strength, pliability, and long vascular pedicle that characterize such grafts make them particularly suitable for this type of repair. The results in six case...
neoplasms
Effects of doxazosin on blood pressure, renin-angiotensin-aldosterone and urinary kallikrein. Doxazosin, a new quinazoline-derivative postsynaptic alpha 1-adrenoceptor antagonist, was studied in this randomized, double-blind, placebo-controlled 12-week study. Its effects on blood pressure (BP), heart rate, metabolic fu...
cardiovascular diseases
Effect of severe pulmonary hypertension on the calculation of mitral valve area in patients with mitral stenosis. We studied 50 consecutive patients with mitral valve stenosis (MS) by cardiac catheterization and Doppler echocardiography to assess whether the presence of severe pulmonary hypertension affected the calcul...
cardiovascular diseases
Lipomatous hamartoma of the orbit. Proliferations of mature adipose tissue, while common in retroperitoneal and subcutaneous sites, rarely occur in the orbit. We describe the clinical, radiographic, and histopathologic findings of a nonencapsulated lipomatous tissue overgrowth of the right orbit in a 35-year-old man. T...
neoplasms
Role of perfusion pressure and flow in major organ dysfunction after cardiopulmonary bypass. The role of perfusion pressure and flow during cardiopulmonary bypass with moderate hypothermia and hemodilution in the development of new postoperative renal or clinically apparent cerebral dysfunction was examined in 504 adul...
cardiovascular diseases
A prospective randomized study of cerebrospinal fluid drainage to prevent paraplegia after high-risk surgery on the thoracoabdominal aorta. This article is concerned with the study of the effect of several variables, principally that of cerebrospinal fluid drainage, on the incidence of neurologic deficit in a prospecti...
general pathological conditions
The perception of life events and daily stress in nonulcer dyspepsia. Previous studies on the association of nonulcer dyspepsia with major life events were performed without emphasis on the perception of these events, and have yielded conflicting results. The present study examined the perception of life events and, in...
general pathological conditions
Colobronchial fistula: a rare complication of Crohn's colitis. A 29-yr-old white woman presented with chronic pneumonia in the left lower lobe and with left pleural effusion. She was known to have inflammatory bowel disease, but she was asymptomatic under maintenance treatment with 5-ASA. She received numerous antibiot...
digestive system diseases
Verapamil increases serum alkaline phosphatase in hypertensive patients. In rats, verapamil decreases intestinal absorption of calcium, increases serum parathyroid hormone (PTH), and induces osteopenia. In this prospective study, verapamil 80-120 mg three times daily was given for 2 months to 20 patients with hypertens...
cardiovascular diseases
Postmortem chorionic villus sampling is a better method for cytogenetic evaluation of early fetal loss than culture of abortus material. In utero chorionic villus sampling at the time of diagnosis of intrauterine fetal death is compared with more traditional use of cultured fetal skin, products of conception, or amnioc...
general pathological conditions
Glucose and fat metabolism during short-term starvation in cirrhosis. To evaluate the metabolic consequences of short-term (i.e., less than 24 hours) starvation, glucose and fat metabolism were studied in eight healthy subjects and in eight patients with stable cirrhosis after 16-hour and again after 22-hour starvation...
digestive system diseases
Muscle fibre type and habitual snoring. Although anatomical abnormalities of the upper airway have been recorded in some patients with obstructive sleep apnoea (OSA), a muscle tone dysregulation also seems to have an important role in this disorder. Since habitual snoring is the initial stage of OSA, the structural cha...
neoplasms
Trichothiodystrophy with chronic neutropenia and mild mental retardation. Trichothiodystrophy is a feature of several diseases that consist of characteristic hair shaft abnormalities and a wide spectrum of other developmental defects. Detection of sulfur-deficient hairs identifies this disorder and separates it from ot...
nervous system diseases
Improved cannulation method for extracorporeal membrane oxygenation. Extracorporeal membrane oxygenation has been shown to be useful for patients in reversible cardiogenic shock. Effective arterial cannulation techniques for infants have been developed that are simple to use and require minimal subsequent vascular repa...
cardiovascular diseases
A comparison between single and double dose intravenous Timentin for the prophylaxis of wound infection in elective colorectal surgery. A prospective, randomized, single-blind, controlled clinical trial was undertaken to determine whether two doses of systemic Timentin provided superior prophylaxis against postoperativ...
general pathological conditions
Coronary angioplasty in patients with severe left ventricular dysfunction. The applications for coronary angioplasty have greatly expanded and the procedure is now increasingly used in complex and potentially high risk conditions. This report describes the short- and long-term effects of coronary angioplasty in 61 pati...
cardiovascular diseases
The association of carotid artery stenosis with carotid sinus hypersensitivity. Transitory cerebral ischaemic attack provoked by carotid sinus reflex The association of internal carotid stenosis with the carotid sinus syndrome represents a special clinical entity. Transitory cerebral ischaemic attack (TIA) will usually...
nervous system diseases
Transient neuromuscular impairment resulting from prolonged inhalation of halothane and enflurane. Inhalation anesthesia first with halothane followed by enflurane relieved a patient with status asthmaticus who was refractory to conventional therapy including mechanical ventilation. After 13 days of anesthesia while on...
nervous system diseases
Selective evaluation and management of coronary artery disease in patients undergoing repair of abdominal aortic aneurysms. A 16-year experience. Reduction of cardiac mortality associated with abdominal aortic aneurysm (AAA) repair remains an important goal. Five hundred consecutive urgent or elective operations for in...
cardiovascular diseases
Control of interleukin-1 beta expression by protein kinase C and cyclic adenosine monophosphate in myeloid leukemia cells. We have examined the signal transduction pathways leading to the expression of the interleukin-1 beta (IL-1 beta) gene in human myeloid leukemia cells lines. Two cell lines representing different s...
neoplasms
Fetal death due to nonlethal maternal carbon monoxide poisoning. Fetal death due to acute carbon monoxide poisoning is rarely reported in the medical literature. Of the eight cases found in literature review, only one documented the fetal carboxyhemoglobin concentration. This paper reports a fetal death due to accident...
general pathological conditions
Nonpigmented congenital iris stromal cyst. A nonpigmented iris stromal cyst was observed in the right eye of a 6-week-old girl. There was no past history of trauma or use of topical miotics, and the remainder of the ocular examination was normal. The pathophysiology and management of this rare developmental anomaly are...
neoplasms
The current spectrum of peptic ulcer disease in the older age groups. Not only has there been a relative increase in the prevalence of peptic ulcer disease (PUD) among America's older age groups, but the characteristics of PUD in these patients differ significantly from those of the general population. Seventy-two cons...
general pathological conditions
Urticaria: current therapy. Although the ideal treatment for urticaria is identification and removal of its cause, no underlying cause can be discerned in the majority of instances. The chief clinical problem is the treatment of chronic idiopathic urticaria. H1-receptor antagonists are the major class of therapeutic ag...
cardiovascular diseases
Malignant melanoma presenting as nasal obstruction. Mucosal melanomas arising in the nasal cavity are rare tumors comprising less than 1 percent of all melanomas. Often, the common clinical symptom is nasal obstruction. Grossly, they may or may not be pigmented and frequently attain large sizes. Histologic diagnosis of...
neoplasms
Initial evaluation of heart murmurs: are laboratory tests necessary? Heart murmurs, most of them innocent, are the most common reason for referrals to a pediatric cardiologist. In the evaluation of murmurs, the electrocardiogram and echocardiogram are often included. The purpose of this study was to determine the utili...
cardiovascular diseases
Noninvasive estimation of left atrial pressure in patients with congestive heart failure and mitral regurgitation by Doppler echocardiography. A completely noninvasive method for estimating left atrial pressure in patients with congestive heart failure and mitral regurgitation has been devised with the use of continuou...
cardiovascular diseases
End-stage renal disease--is infrainguinal limb revascularization justified? Reports of reconstructive surgery for peripheral vascular disease have been relatively uncommon in patients with end-stage renal disease. Between 1980 and 1989, 39 patients with end-stage renal disease underwent revascularization of 56 limbs. F...
cardiovascular diseases
Persistent mullerian duct syndrome. Persistent mullerian syndrome is rare. A case of phenotypically normal male with persistent mullerian structures that consisted of a bicornuate uterus, fallopian tubes, and upper third of the vagina is reported. These unusual structures were found in association with bilateral crypto...
digestive system diseases
Psychosocial adjustment in women with breast cancer. There is a plethora of studies investigating psychosocial adjustment in women with breast cancer, its correlates, clinical course, and prognosis. These studies have been conducted with varying degrees of methodologic rigor. An assessment has been made of the quality ...
neoplasms
Impedance tympanometry and acoustic reflectometry at myringotomy [published erratum appears in Pediatrics 1991 Jun;87(6):945] A total of 220 ears undergoing myringotomy and pressure-equalizing tube placement were studied with impedance tympanometry and acoustic reflectometry in a direct comparison for detection of midd...
general pathological conditions
General assay for phosphoproteins in cerebrospinal fluid: a candidate marker for paraneoplastic cerebellar degeneration. The components of protein phosphorylation systems (protein kinases, protein phosphatases, and their phosphoprotein substrates) are highly enriched in neuronal cells compared with other cell types. We...
nervous system diseases
Emphysematous gastritis: case report and review. Emphysematous gastritis is a condition involving gastric wall inflammation, radiologic or intraoperative evidence of intramural gas, and systemic toxicity. A recent case of emphysematous gastritis in a 57-year-old diabetic man is reported, and 27 cases published since 18...
general pathological conditions
Diagnosis of left atrial thrombi in mitral valve disease by coronary arteriography. Arteriographic findings of neovascularity and fistula formation between coronary arteries and left atrium have occasionally been described in association with left atrial thrombosis in patients with mitral valve disease. The validity of...
cardiovascular diseases
Aspiration pneumonia and the laryngeal mask airway A case of aspiration pneumonia is reported after the use of a laryngeal mask airway in a young woman undergoing an elective cholecystectomy. The case illustrates the hazards of regurgitation with the laryngeal mask airway and the need for further evaluation when used w...
general pathological conditions
Sclerotherapy for esophageal varices. Endoscopic injection sclerotherapy (EIS) frequently is used for patients with esophageal varices, both for controlling acute hemorrhage and for prophylaxis. An old technique, interest in EIS increased when other methods did not improve patient outcomes. Clinical trials of EIS for a...
digestive system diseases
Local hypothermia to prolong safe tourniquet time. Local hypothermia was studied as a method to safely prolong tourniquet time for reconstructive procedures of the upper extremity. An ice blanket constructed of flannel cloth and cold gel packs was applied to the limb for 45 minutes preoperatively. Seventy-eight patient...
cardiovascular diseases
Ablation of the cystic duct and the gallbladder. Experimental basis and initial clinical observations. Bipolar radiofrequency electrocoagulation of the cystic duct by catheter can be performed safely and reproducibly using fluoroscopic control and induces endoluminal scar formation. The scar within the cystic duct form...
digestive system diseases
Preliminary characterization of growth factors secreted by human pituitary tumors. To investigate the secretion of mitogenic factors by human pituitary tumors we have cultured cells from 54 adenomas in serum-free medium. Conditioned media from 28 (52%) elicited dose-dependent stimulation of [3H]thymidine incorporation ...
neoplasms