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e461a8c5_apter_16_Flashcards___Cram_com__tand_evolution__Not_always_bad
[Why are mutations important?] Describe 5-bromouracil.
Base analog: mutagenic chemicals that can substitute for purines or pyrimides during nucleic acid synthesis. Look up in notes.
[]
Genetics Chapter 16 Flashcards - Cram.com
Basis of genetic analysis. Needed to understand evolution. Not always bad
http://www.cram.com/flashcards/genetics-chapter-16-2013327
10/1438042988065.26_20150728002308-00162-ip-10-236-191-2_387603751_0.json
e461a8c5_apter_16_Flashcards___Cram_com__tand_evolution__Not_always_bad
[Why are mutations important?] Discuss alkylating agents:
Add methyl/ketyl group to amino/keto groups of bases: same thing as base analogs
[]
Genetics Chapter 16 Flashcards - Cram.com
Basis of genetic analysis. Needed to understand evolution. Not always bad
http://www.cram.com/flashcards/genetics-chapter-16-2013327
10/1438042988065.26_20150728002308-00162-ip-10-236-191-2_387603751_0.json
e461a8c5_apter_16_Flashcards___Cram_com__tand_evolution__Not_always_bad
[Why are mutations important?] Discuss acridine dyes.
ethydium bromide causes insertion/deletion mutations becasue intercoloring agents fits between bases.
[]
Genetics Chapter 16 Flashcards - Cram.com
Basis of genetic analysis. Needed to understand evolution. Not always bad
http://www.cram.com/flashcards/genetics-chapter-16-2013327
10/1438042988065.26_20150728002308-00162-ip-10-236-191-2_387603751_0.json
e461a8c5_apter_16_Flashcards___Cram_com__tand_evolution__Not_always_bad
[Why are mutations important?] Discuss UV light and mutations.
Cannot be reversed back to original form. Causes dimers to be made: covalent bonds between T residues. Dimers cause DNA conformational changes, can be skipped during replication... causes mistakes to occur.
[]
Genetics Chapter 16 Flashcards - Cram.com
Basis of genetic analysis. Needed to understand evolution. Not always bad
http://www.cram.com/flashcards/genetics-chapter-16-2013327
10/1438042988065.26_20150728002308-00162-ip-10-236-191-2_387603751_0.json
e461a8c5_apter_16_Flashcards___Cram_com__tand_evolution__Not_always_bad
[Why are mutations important?] Ames test.
Tests for mutagens, NOT carcinogens.
[]
Genetics Chapter 16 Flashcards - Cram.com
Basis of genetic analysis. Needed to understand evolution. Not always bad
http://www.cram.com/flashcards/genetics-chapter-16-2013327
10/1438042988065.26_20150728002308-00162-ip-10-236-191-2_387603751_0.json
e461a8c5_apter_16_Flashcards___Cram_com__tand_evolution__Not_always_bad
[Why are mutations important?] Discuss DNA repair during replication.
DnA pol can go back and replace wrong bases.
[]
Genetics Chapter 16 Flashcards - Cram.com
Basis of genetic analysis. Needed to understand evolution. Not always bad
http://www.cram.com/flashcards/genetics-chapter-16-2013327
10/1438042988065.26_20150728002308-00162-ip-10-236-191-2_387603751_0.json
e461a8c5_apter_16_Flashcards___Cram_com__tand_evolution__Not_always_bad
[Why are mutations important?] How does it know which is the template vs. new strand?
Adenine methylase recognizes sequence GATC and adds methyl to adenine. New strand is temporarily unmethylated bc methylase lags behind polymerase.
[]
Genetics Chapter 16 Flashcards - Cram.com
Basis of genetic analysis. Needed to understand evolution. Not always bad
http://www.cram.com/flashcards/genetics-chapter-16-2013327
10/1438042988065.26_20150728002308-00162-ip-10-236-191-2_387603751_0.json
e461a8c5_apter_16_Flashcards___Cram_com__tand_evolution__Not_always_bad
[Why are mutations important?] Discuss excision repair.
Error clipped out by endonuclease DNA pol I fills in gap Ligase seals backbone
[]
Genetics Chapter 16 Flashcards - Cram.com
Basis of genetic analysis. Needed to understand evolution. Not always bad
http://www.cram.com/flashcards/genetics-chapter-16-2013327
10/1438042988065.26_20150728002308-00162-ip-10-236-191-2_387603751_0.json
e461a8c5_apter_16_Flashcards___Cram_com__tand_evolution__Not_always_bad
[Why are mutations important?] Discuss base excision repair.
corrects damage to bases from chemicals
[]
Genetics Chapter 16 Flashcards - Cram.com
Basis of genetic analysis. Needed to understand evolution. Not always bad
http://www.cram.com/flashcards/genetics-chapter-16-2013327
10/1438042988065.26_20150728002308-00162-ip-10-236-191-2_387603751_0.json
e461a8c5_apter_16_Flashcards___Cram_com__tand_evolution__Not_always_bad
[Why are mutations important?] Discuss nucelotide excision repai
corrects bulky lesions in DNA tha alter double helix
[]
Genetics Chapter 16 Flashcards - Cram.com
Basis of genetic analysis. Needed to understand evolution. Not always bad
http://www.cram.com/flashcards/genetics-chapter-16-2013327
10/1438042988065.26_20150728002308-00162-ip-10-236-191-2_387603751_0.json
e461a8c5_apter_16_Flashcards___Cram_com__tand_evolution__Not_always_bad
[Why are mutations important?] Double strand break repair.
Last resort. Enzyme recognizes double strand break. 5' end of break is digested. 3' end looks for complementary sequence and aligns with it.
[]
Genetics Chapter 16 Flashcards - Cram.com
Basis of genetic analysis. Needed to understand evolution. Not always bad
http://www.cram.com/flashcards/genetics-chapter-16-2013327
10/1438042988065.26_20150728002308-00162-ip-10-236-191-2_387603751_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Neisseria meningitis • Gram-negative diplococci • 12 antigenic serotypes - Most serioues infections due to types A, B, C, and Y
Meningococcal Meningitis Causative Agent
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Acquired by inhaling infected respiratory droplets – Bacteria adhere to mucous membranes via pili and multiply – Invade bloodstream by passing through respiratory epithelium • Bloodstream carries organisms to CSF – Organisms phagocytized by PMNs • Enter fluid in large numbers – Inflammation causes swelling and infarcts to brain tissue • Can also cause obstruction of outflow of CSF – Causes brain to squeeze against skull – Release of endotoxin causes drop in blood pressure leading to shock
Meningococcal Meningitis Pathogenesis
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– N. meningitis more prone to cause epidemics • Reasons unknown – Can spread rapidly in due to types A,B,C and Y crowded stressed places – Human only source of infection – Transmission can occur with disease or asymptomatic carrier • Organism recovered from 5% - 15% of healthy individuals
Meningococcal Meningitis Epidemiology
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
• The decline in meningitis due to H.influenzae has resulted in a marked overall decrease in bacterial meningitis and a shift in the peak incidence in older age groups • Streptococcus pneumoniae is the leading cause of meningitis in adults
Meningococcal Meningitis
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Most cases asymptomatic – Symptoms include • Fever and muscle aches • Sometimes nausea and diarrhea • 75% of cases coming to medical attention have meningitis – With typical symptoms of meningitis
Listeriosis Symptoms
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Listeria monocytogenes • Motile, non-spore forming, facultative anaerobe, Gram (+) rod
Listeriosis Causative Agent
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Mode of entry usually obscure • Generally thought to enter through GI tract – Bacteria penetrate intestinal mucosa then enter the bloodstream • Leads to bacteremia – Organism can cross the placenta • Produces abscesses in fetal tissues • Babies usually develop meningitis after 1-4 week incubation period
Listeriosis Pathogenesis
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Widespread in natural waters and vegetation – Can be carried asymptomatically in animals and humans – Occurs on all continents except Antarctica – Pregnant women, elderly and immuncompromised at highest risk • Advised to refrain from soft cheeses and reheat leftovers – Epidemics have resulted from contaminated foods • Organism can survive in commercially prepared foods and at refrigeration temperatures
Listeriosis Epidemiology
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Begins gradually • Usually with onset of increased or decreased sensation in certain areas of skin • These areas usually have changes in pigmentation – Affected areas later enlarge and thicken – Loss of hair, ability to sweat and sensation – Nerves in extremities visibly enlarge – Changes most obvious in face
Hansen's Disease (leprosy) Symptoms
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Mycobacterium leprae • Aerobic, acid-fast, rod shaped – Grows slowly • Generation time approximately 12 days
Hansen's Disease (leprosy) Causative agent
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Earliest detectable findings in humans is infection of small nerves of skin – Only know human pathogen to preferentially attack peripheral nerves – Grows slowly within macrophages – Disease may spontaneously stop progressing – Tuberculoid leprosy » Rarely transmitted to others – Uncommon form termed lepromatous leprosy • High numbers of bacteria in mucous membranes with very little inflammation
Hansen's Disease (leprosy) Pathogenesis
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Transmission via direct human-to-human contact • Disease develops in small number of people – Controlled by body defenses – Natural infections occur in wild nine banded armadillos and mangabey monkeys • Armadillos not a source of human infection
Hansen's Disease (leprosy) Epidemiology
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– No proven vaccine – Dapsone and rifampin used to arrest tuberculoid leprosy • Treated for 6 months • Lepromatous treated for 2 years – Combination therapy required to control resistance
Hansen's Disease (leprosy) Prevention and Treatment
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Begins 12 to 36 hours post ingestion of contaminated foods – Begins with dizziness, dry mouth and blurred vision – Abdominal symptoms include pain, nausea, vomiting and diarrhea or constipation – Progressive paralysis ensues • Paralysis of respiratory muscles most common cause of death • Paralysis distinguishes botulism from other forms of food poisoning
Botulism Symptoms
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
Clostridium botulinum • Gram (+), spore forming rod shaped – Endospores generally resist boiling for hours • Killed by autoclaving – Produces toxin • 7 different toxins – A, B, C1, D, E, F, G » All produced by different strains – A, B, E, F responsible for most human cases
Botulism Causative Agent
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Spores germinate in favorable environment • Bacterial growth results in toxin release – Toxin resists digestion and is absorbed by small intestine – Toxin can circulate in blood stream for 3 weeks or more – Toxin is neurotoxin • Acts against nervous system • One of most powerful poisons known • Toxin attaches to motor nerves blocking function of neurotransmitter – Causes paralysis – Toxin is AB toxin • B portion binds and A portion enters nerve cell
Botulism Pathogenesis
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Prevention depends on proper sterilization and sealing of canned food – Heating food to 100°C for 15 minutes just prior to eating generally makes food safe to eat • Can’t rely on smell, taste or appearance to detect contamination – Treated by intravenous administration of antitoxin ASAP • Antitoxin only neutralizes circulating toxin • Affected nerves recover slowly – Gastric washing and surgical removal of tissues removes unabsorbed toxin – Artificial respiration may be required for prolonged periods
Botulism Prevention and Treatment
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Typically abrupt in onset – Characterized by • Fever • Severe headache above or behind eyes • Stiff neck with increased pain on forward flexion • Sensitivity to light • Nausea and vomiting • May have sore throat, chest pain, swollen glands and skin rash – Depends on causative agent
Viral Meningitis Symptoms
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
VViral Meningitis • Symptoms – Typically abrupt in onset – Characterized by • Fever • Severe headache above or behind eyes • Stiff neck with increased pain on forward flexion • Sensitivity to light • Nausea and vomiting • May have sore throat, chest pain, swollen glands and skin rash – Depends on causative agent • Causative agent – Small, non-enveloped RNA virus – Member of the enterovirus subgroup of picornavirus family – Responsible for at least half of viral meningitis cases • Most common offenders are Coxsackie virus and Echovirus
Viral Meningitis Causative Agent
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Begins with infection of throat and intestinal epithelium • Progresses to lymphoid tissue in the bloodstream – Viremia results in meningeal infection • May also be responsible for rash and chest pain
Viral Meningitis Pathogenesis
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
Enteroviruses transmitted by the fecal-oral route, mumps by respiratory secretions and saliva. Enteroviruses transmission mainly summer and early fall; mumps in fall an d winter.
Viral Meningitis Epidemiology
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
Handwashing, avoiding crowded swimming pools during enterovirus epidemics; mumps vaccine for mumps prevention. No specific treatment.
Viral Meningitis Prevention and Treatment
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
• Symptoms – Onset usually abrupt – Characterized by • Fever • Headache • Vomiting • One or more nervous system abnormalities – Disorientation, localized paralysis, deafness, seizures or coma
Viral Encephalitis Symptoms
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
West Nile Virus – Arboviruses • Arthropod borne viruses – Transmitted by insects, mites and ticks – Viruses enveloped single-stranded RNA viruses
Viral Encephalitis Causative Agent
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
• Pathogenesis – Knowledge of pathogenesis incomplete – Viruses multiply at site of bite and in local lymph nodes • Produces viremia – Virus crosses blood-brain barrier • Mechanism unknown – Progression of disease halted with appearance of neutralizing antibody – Mortality ranges from 2% to 50% depending on agent
Viral Encephalitis Pathogenesis
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Only minority infected develop encephalitis • Other develop viral meningitis – Disease are all zoonoses • Maintained naturally in birds and rodents – Humans are accidental hosts – LaCrosse encephalitis usually causes most cases of encephalitis
Viral Encephalitis Epidemiology
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Virus widespread in areas where sanitation is poor • Virus usually spread via fecal-oral route – In endemic areas people generally do not escape childhood without contracting disease – Babies receive antibodies transplacental • Babies develop disease within 2 to 3 months of age – Develop lifelong immunity
Infantile Paralysis (Polio) Epidemiology
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Virus stable under natural conditions – Control directed at vaccination
Infantile Paralysis (Polio) Prevention and Treatment
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
- Infects throat and intestine - Circulates via bloodstream - Enters some motor nerve cells of brain or spinal cord - Infected nerve cells lyse upon release of mature virus
Infantile Paralysis (Polio) Pathogenesis
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
Spreads by fecal-oral route; asymptomatic and nonparalytic cases common
Infantile Paralysis (Polio) Epidemiology
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
Injected Salk's inactivated disease or Sabin's orally administered attenuated vaccine Treatment: artificial ventiliation for respiratory paralysis; physical therapy and rehabilitation
Infantile Paralysis (Polio) Prevention and treatment
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Fever/Fatigue – Head and muscle ache – Sore throat – Nausea – Tingling/twitching at site of viral entry – Early symptoms begin 1 to 2 months post infection • Progress rapidly to secondary symptoms of – Encephalitis, agitation, confusion, hallucinations, seizure, increased sensitivity to light and touch • Body temperature rises with increased salivation and difficulty swallowing – Results in frothing of mouth • Hydrophobia occurs in 50% of cases • Coma develops • About 50% of patients die within 4 days after onset
Rabies Symptoms
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Rabies virus • Member of rhabdovirus family • Sticking bullet shape • Enveloped, single-stranded RNA genome
Rabies Causative Agent
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Mode of transmission primarily via saliva of rabid animal • Usually due to bite or abrasion • Can be contacted via inhalation – Virus multiples in muscle cells at site of infection – Virus reaches brain via infected nerve • Virus multiplies extensively in brain • Negri bodies form at sites of replication
Rabies Pathogenesis
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
Widespread in wild animals • 5,000 cases reported annually in United States – Skunks, raccoons and bats considered chief reservoir • Raccoons most infected • Almost all human cases due to contact with infected bats – Zero to 4 reported cases in U.S annually • Only 25% have history of dog bite • Long incubation period of virus make history unreliable
Rabies Epidemiology
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Wash wound immediately and thoroughly • Use soap and water and apply antiseptic – Risk of developing rabies from bite of rabid dog is approximately 30% • Risk can be lowered considerably if vaccine is administered as soon as possible after exposure – Presumably vaccine provokes better immune response – Bitten individual should receive series of 5 injections at wound site and intramuscularly • Shots should be given even if biting animal presumed to be rabid – No effective treatment for rabies • Only six known survivors of disease
Rabies Prevention and Treatment
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
• Symptoms – Develop gradually in healthy individuals – Generally consist of • Difficulty thinking • Dizziness • Intermittent headache • Slight or no fever – Slow progression of disease results in other symptoms • Vomiting • Weight loss • Paralysis • Seizures • Coma
Cryptococcal Meningioencephalitis Symptoms
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Yeast form of Filobasidiella neoformans fungus – Small, spherical yeast – Generally surrounded by large capsule
Cryptococcal Meningioencephalitis Causative Agent
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Fungus becomes airborne in dust • Enters body via inhalation and establishes infection first in lung – Infection often eliminated by body defenses – Organism multiplies and enters bloodstream – Capsule inhibits phagocytosis and neutralizes opsonins – Organisms typically cause thickening of meninges • This can often impede the flow of CSF • Also invade brain tissue producing abscesses
Cryptococcal Meningioencephalitis Pathogenesis
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Distributed worldwide in soil and vegetation • Numerous in soil where pigeon droppings accumulate – For every one case of disease millions are infected with organism – Symptomatic infection often the first indicator of AIDS – Person-to-person spread does not occur
Cryptococcal Meningioencephalitis Epidemiology
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– First symptoms appear within a week after bite from tsetse fly • Nodule develops at site of bite • Regional lymph nodes enlarge – Symptoms may disappear spontaneously – Weeks or years later recurrent fevers develop – CNS involvement marked by gradual loss of interest in everything • Marked by decreased activity and indifference to food – Eyelids droop and individual falls asleep during everyday tasks – Speech becomes slurred followed by coma and death
African Sleeping Sickness Symptoms
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Trypanosoma brucei • Flagellated protozoan • Slender with wavy undulating membrane • Two subspecies – T. brucei rhodesiense » Occurs mainly in cattle-raising areas of East Africa – T. brucei gambiense » Occurs mainly in forested areas of Central and West Africa • Transmitted by tsetse fly
African Sleeping Sickness Causative Agent
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Protozoan enters through bite in fly saliva – Organism multiplies at skin and migrates to lymphatic and blood circulation • Body responds with fever and IgM antibody – Symptoms improve – Period followed by recurrent increases in numbers of parasite • Termed parasitemica – Parasitemia and antibody production continue until treatment or death – T. brucei rhodesiense infections progress quickly often with major system involvement with 6 weeks and death in 6 months – T. brucei gambiense infections progress much more slowly
African Sleeping Sickness Pathogenesis
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Disease occurs on African continent within 15° of equator – 10,000 to 20,000 new cases annually – Occurrence of disease is determined by distribution of tsetse fly – Wild animals main reservoir for Rhodesian form – Humans are main reservoir for Gambian form • Human-to-human transmission more common
African Sleeping Sickness Epidemiology
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Early symptoms • Vague behavioral changes • Anxiety • Insomnia • Fatigue – These symptoms progress weeks to months to hallmark symptoms • Muscle jerks • Lack of coordination • Dementia • Deteriorating intellectual function • Impaired judgment • Memory loss – Disease often progresses to death within a year
Transmissible Spongiform Encephalopathies Symptoms
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Proteinaceous infectious particles • a.k.a prions • Appear to be new class of infectious agent – Differ from bacteria, viruses and viroids – Main characteristics • Increase in quantity during incubation period • Resist inactivation via UV and ionizing radiation • Resist inactivation by formaldehyde and heat • Not readily destroyed by proteases • Not destroyed by nucleases • Much smaller than smallest virus • Composed of protein coded by normal cellular gene – Modified after transcription – Apparently arose following gene encoding normal prion protein – Mutation caused protein to have different folding properties – Mutated protein resistant to proteases • Normal protein sensitive – Resists UV light and nucleases • Due to lack of nucleic acid – Inactivated by chemicals that denature proteins
Transmissible Spongiform Encephalopathies Causative agent
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Creutzfeld-Jakob occurs in humans over age 45 • Human-to-human transmission has occurred via corneal transplants – Scrapie found in sheep • Most likely transmitted from ewe to lamb – Mad cow disease result of cattle exposed to scrapie in cattle feed – New varient Creutzfeld-Jakob mostly likely due to exposure of human to mad cow disease • Median age of onset of NVCJ is 28 years
Transmissible Spongiform Encephalopathies Epidemiology
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– Prions inactivated by autoclaving in 1N NaOH – No treatment • All forms are fatal
Transmissible Spongiform Encephalopathies Prevention and Treatment
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
b652710f_fections_Flashcards___Cram_com__ingococcal_Meningitis_Symptoms
– No inflammatory or immune response produced – Replication depends on presence of normal cellular protein • Replicate by converting normal protein into copies of themselves – Normal course of infections • Replication in spleen – Most likely in dendritic cells • Then transported to nervous system via nerve axon • Prions aggregate in insoluble masses in nerve cells – Causes malfunction and death
Transmissible Spongiform Encephalopathies Pathogenesis
[]
12 Pathogens, Exam 3, CNS infections Flashcards - Cram.com
Meningococcal Meningitis Symptoms
http://www.cram.com/flashcards/12-pathogens-exam-3-cns-infections-1543342
10/1438042992201.62_20150728002312-00185-ip-10-236-191-2_377615802_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
>INSERT >Slides from files> Slide finder>BROWSE to file >OPEN FILE>select slides.
Which feature do you use to copy slides from one presentation to another?
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
To allow others to review and provide feedback.
Why would you save a presentation as a presentation for review.
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
In the slide pane & in slide layout pane INSERTS BELOW currently selected slide.
Clicking the new slide button on the formatting toolbar will insert a new slide WHERE?
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
PLACEHOLDER BORDER MOve the placeholder by positioning teh mouse pointer on teh border of the placeholder until the pointer displays with a 4 headed arrow.
To move a table in a slide point to which table component?
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
highlight and drag pointer to all cells or point into one box on the table and >EDIT >SELECT ALL
Know to select all cells in a table
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
On the left side in a single column.
With the slide tab selected, how are individual slides displayed?
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
Creates a presentation - new presentation task pane displays at right side of screen. The presentation is created with sample ideas for text to be filled in.
Know what the autocontent wizard does.
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
+ to promote demotes
Which two keys do you press to promote the insertion point to the previous level?
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
TAB
Know which Keys you press to demote to the next level
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
Right side of screen. name varies. Slide Design Task Pane, Slide Layout Task Pane. PRESENTS FEATURES TO HELP YOU EASILY IDENTIFY AND USE MORE OF THE PROGRAM.
What does the task pane do?
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
It shows at the bottom of the page in small print on every slide.
What is a footer?
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
Number of rows and columns.
When inserting a table in a slide which items must be specified?
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
change background color, shape fills.
Know when / why you would use the fill color button.
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
WMF - metafile format
what is the file category of most clip art pictures?
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
resize or crop a picture to fit better, reduce file size.
Why would you use crop?
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
To replace a fons universally throughout a presentation.
When would you use replace fonts?
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
Place the insertion point in the object, and then press CTRL+A
Press these keys on the keyboard to select all text in the placeholder
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
FORMAT OBJECT FORMAT>OBJECT
recolor a clip art image with options at this dialog box.
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MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
SLIDESHOW>Annimation schemes
Display animation schemes in the slide design task pane by clicking this option on the menu bar
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MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
Format>LINE SPACING
Specify spacing before a paragraph with options at this dialog box
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MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
Outline/slides pane
This pane contains two tabs and displays at teh left side of the window in normal view.
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
slide sorter view
click this button on the VIEW toolbar and all slides in the presentation display in slide miniature.
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
normal view, slide sorter view, and slideshow from current slide
button on the VIEW toolbar shows what views?
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
AUTOFIT OPTIONS APPEARS - stop fitting or autfit text
if text is bigger than placeholder?
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
NEW LINE COMMAND, SHIFT+ENTER inserts a new line that is considered part of the previous paragraph.
Create a blank line between bulleted items without creating another bullet
[]
MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
serif
Text intensive slides use what type of font?
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MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
sans-serif
headings subtitles and titles and short text items use what type of font?
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MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
a79ffc49_T_CIS120_Flashcards___Cram_com___on_a_presentation_you_review_
position arrow pointer over slide hold down CTR key and left mouse button drag to location you want
in slide sorter view, how do you move a slide?
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MS POWERPOINT CIS120 Flashcards - Cram.com
Changing the username and initials to your name & initials will have what effect on a presentation you review?
http://www.cram.com/flashcards/ms-powerpoint-cis120-346368
10/1438042988065.26_20150728002308-00000-ip-10-236-191-2_389290877_0.json
011d77b2_mester_1_Flashcards___Cram_com__1
[2] Connected with or related to the matter at hand. [1]
Relevant
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English Trimester 1 Flashcards - Cram.com
1
http://www.cram.com/flashcards/english-trimester-1-3105814
10/1438042992201.62_20150728002312-00312-ip-10-236-191-2_379681801_0.json
011d77b2_mester_1_Flashcards___Cram_com__1
[2] To develop gradually; to rise to a higher level [1]
Evolve
[]
English Trimester 1 Flashcards - Cram.com
1
http://www.cram.com/flashcards/english-trimester-1-3105814
10/1438042992201.62_20150728002312-00312-ip-10-236-191-2_379681801_0.json
011d77b2_mester_1_Flashcards___Cram_com__1
[2] A literary work or film continuing the story of one written or made earlier [1]
Sequel
[]
English Trimester 1 Flashcards - Cram.com
1
http://www.cram.com/flashcards/english-trimester-1-3105814
10/1438042992201.62_20150728002312-00312-ip-10-236-191-2_379681801_0.json
011d77b2_mester_1_Flashcards___Cram_com__1
[2] A person or thing of no importance [1]
Nonentity
[]
English Trimester 1 Flashcards - Cram.com
1
http://www.cram.com/flashcards/english-trimester-1-3105814
10/1438042992201.62_20150728002312-00312-ip-10-236-191-2_379681801_0.json
011d77b2_mester_1_Flashcards___Cram_com__1
[2] Ridiculous and unpredictable behavior or actions [1]
Antics
[]
English Trimester 1 Flashcards - Cram.com
1
http://www.cram.com/flashcards/english-trimester-1-3105814
10/1438042992201.62_20150728002312-00312-ip-10-236-191-2_379681801_0.json
011d77b2_mester_1_Flashcards___Cram_com__1
[2] To reduce to nothing; to declare legally invalid or void [1]
Annul
[]
English Trimester 1 Flashcards - Cram.com
1
http://www.cram.com/flashcards/english-trimester-1-3105814
10/1438042992201.62_20150728002312-00312-ip-10-236-191-2_379681801_0.json
011d77b2_mester_1_Flashcards___Cram_com__1
[2] To work with; to work together [1]
Collaborate
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English Trimester 1 Flashcards - Cram.com
1
http://www.cram.com/flashcards/english-trimester-1-3105814
10/1438042992201.62_20150728002312-00312-ip-10-236-191-2_379681801_0.json
011d77b2_mester_1_Flashcards___Cram_com__1
[2] Humorous, not meant seriously [1]
Facetious
[]
English Trimester 1 Flashcards - Cram.com
1
http://www.cram.com/flashcards/english-trimester-1-3105814
10/1438042992201.62_20150728002312-00312-ip-10-236-191-2_379681801_0.json
011d77b2_mester_1_Flashcards___Cram_com__1
[2] (v) To exchange playful remarks, tease (n) Talk that is playful and teasing [1]
Bantering
[]
English Trimester 1 Flashcards - Cram.com
1
http://www.cram.com/flashcards/english-trimester-1-3105814
10/1438042992201.62_20150728002312-00312-ip-10-236-191-2_379681801_0.json
011d77b2_mester_1_Flashcards___Cram_com__1
[2] To regard with reverence, look up to with great respect [1]
Venerated
[]
English Trimester 1 Flashcards - Cram.com
1
http://www.cram.com/flashcards/english-trimester-1-3105814
10/1438042992201.62_20150728002312-00312-ip-10-236-191-2_379681801_0.json
011d77b2_mester_1_Flashcards___Cram_com__1
[2] A high point of land extending into water [1]
Promontory
[]
English Trimester 1 Flashcards - Cram.com
1
http://www.cram.com/flashcards/english-trimester-1-3105814
10/1438042992201.62_20150728002312-00312-ip-10-236-191-2_379681801_0.json
011d77b2_mester_1_Flashcards___Cram_com__1
[2] To feel or express regret or disapproval [1]
Deplore
[]
English Trimester 1 Flashcards - Cram.com
1
http://www.cram.com/flashcards/english-trimester-1-3105814
10/1438042992201.62_20150728002312-00312-ip-10-236-191-2_379681801_0.json