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1784 33846634 pubmed Inoue D (2021) 1-PMID33846634 34 593 No 34 EdgeR All Significant - High Throughput Phenotype Screen Pool Cytokine depletion 7 Days IL-3 withdrawal - - CRISPRn ZRSR2 splicing target library (Abdel-Wahab, 2021) CRISPRn Knockout Cas9 Ba/F3 Pre-B-Lymphocyte Cell Line regulation of signal transduction p... |
1785 33846634 pubmed Inoue D (2021) 2-PMID33846634 50 593 No 50 EdgeR All Significant - High Throughput Phenotype Screen Pool Cytokine depletion 7 Days IL-3 withdrawal - - CRISPRn ZRSR2 splicing target library (Abdel-Wahab, 2021) CRISPRn Knockout Cas9 32Dcl3 bone marrow cell line regulation of signal transduction pheno... |
1838 31509742 pubmed Freeman AJ (2019) 1-PMID31509742 20229 20229 Yes 1048 MaGeCK Score Significance Score.2 (p-Value) < 0.05 High Throughput Negative Selection Pool NK cell exposure 3 Days NK (activated natural killer) cells 1 Ratio of effector cells/target cells = 0.3 Brie (mouse) CRISPRn Knockout Cas9 B16-F10 Melano... |
1839 31509742 pubmed Freeman AJ (2019) 2-PMID31509742 20570 20570 Yes 1066 MaGeCK Score Significance Score.2 (p-Value) < 0.05 High Throughput Phenotype Screen Pool Cytokine exposure 1 Days Interferon gamma 1.0 ng/mL = 0.3 Brie (mouse) CRISPRn Knockout Cas9 B16-F10 Melanoma Cell Line protein/peptide accumulation 4 MaGeC... |
1888 34497417 pubmed Kamber RA (2021) 3-PMID34497417 22898 22898 Yes 372 CasTLE Column Significance - High Throughput Phenotype Screen Pool Other 24 Hours Exposure to magnetic IgG-coated bead - - Bassik Mouse CRISPR Knockout Library CRISPRn Knockout Cas9 J774 macrophage phagocytosis 3 CasTLE Score CasTLE Effect p-Value... |
1889 34497417 pubmed Kamber RA (2021) 4-PMID34497417 22893 22893 Yes 38 CasTLE Column Significance - High Throughput Phenotype Screen Pool Other 72 Hours Exposure to APMAP-KO cancer cells - - Bassik Mouse CRISPR Knockout Library CRISPRn Knockout Cas9 J774 macrophage phagocytosis 3 CERES score CasTLE Effect p-Value - - ... |
1890 34497417 pubmed Kamber RA (2021) 5-PMID34497417 22894 22894 Yes 24 CasTLE Column Significance - High Throughput Phenotype Screen Pool Other 72 Hours Exposure to APMAP-KO cancer cells vs. Control-KO cancer cells - - Bassik Mouse CRISPR Knockout Library CRISPRn Knockout Cas9 J774 macrophage phagocytosis 3 CasTLE Sco... |
1908 35263388 pubmed Ortega-Gonzalez P (2022) 1-PMID35263388 873 20077 No 873 STARS All Significant - High Throughput Positive Selection Pool Virus Exposure 9 Days Virus: Reovirus strains T1L or T3D 100.0 PFU/cell = 0.2 Asagio (mouse) CRISPRn Knockout Cas9 BV-2 Microglial Cell Line response to virus 4 STARS Score p-Val... |
1937 35842423 pubmed Zou Y (2022) 1-PMID35842423 79 20611 No 79 Log2 Fold Change (L2FC) All Significant - High Throughput Positive Selection Pool Cytokine exposure | Drug exposure 48 Hours TNF‐α | Z-VAD-FMK 20 µM < 0.3 GECKO v2 (mouse) CRISPRn Knockout Cas9 NCTC clone 929 Fibroblast Cell Line viability 2 Log2FC p-Value... |
2019 33033111 pubmed Rushworth LK (2020) 1-PMID33033111 17 20611 No 17 MaGeCK All Significant - High Throughput Negative Selection in vivo Drug Exposure - docetaxel 6.0 mg/kg < 0.4 GECKO v2 (mouse) CRISPRn Knockout Cas9 SP1 Breast Cancer Cell Line response to chemicals 2 p-Value Log2FC - - - 10090 M. musculus Hit genes... |
2049 33513212 pubmed McLellan LK (2021) 1-PMID33513212 20144 20144 Yes 9 Log2 Fold Change (L2FC) Score Significance Score.1 (p-Value) > 2.58 AND Score.2 (Log2FC) > 0.0 High Throughput Phenotype Screen Pool Bacteria Exposure 75 Minutes Escherichia coli (str. UTI89) 150.0 MOI = 0.5 Brie (mouse) CRISPRn Knockout Cas9 IMCD... |
2127 35750052 pubmed Belk JA (2022) 1-PMID35750052 17447 17447 Yes 99 Z-score Score Significance Score.3 (FDR) < 0.06 High Throughput Positive Selection Pool Other 10 Days Chronic T cell stimulation - - Teichmann Retroviral Mouse Genome-wide CRISPR Knockout Library CRISPRn Knockout Cas9 CD8+ T s (primary-derived) Regul... |
2141 35379808 pubmed Frey N (2022) 1-PMID35379808 66 19647 No 66 MaGeCK All Significant - High Throughput Positive and Negative Selection Pool T cell exposure 3 Days OT-I T cells 1.0 Ratio of effector cells/target cells = 0.3 Brie (mouse) CRISPRn Knockout Cas9 KPC Pancreatic Ductal Adenocarcinoma Cell Line cell prolife... |
2142 35379808 pubmed Frey N (2022) 2-PMID35379808 64 63 No 64 MaGeCK All Significant - High Throughput Positive and Negative Selection Pool T cell exposure 5 Days OT-I T cells implanted into the pancreata of RAG1-/- mice - = 0.3 Targeted CRISPRn library (Schwank, 2022) CRISPRn Knockout Cas9 KPC Pancreatic Ductal Adenoc... |
2143 35972292 pubmed Sullender ME (2022) 1-PMID35972292 27 22774 No 27 Log2 Fold Change (L2FC) All Significant - High Throughput Positive Selection Pool Virus Exposure 10 Days MNV (murine norovirus) CR6 5.0 MOI ~ 0.4 Caprano CRISPRa Activation dCas9-VP64 BV-2 Microglial Cell Line response to virus 2 Log2FC p-Value - - ... |
2144 35972292 pubmed Sullender ME (2022) 2-PMID35972292 28 22774 No 28 Log2 Fold Change (L2FC) All Significant - High Throughput Positive Selection Pool Virus Exposure 10 Days MNV (murine norovirus) 1 (CW3) 5.0 MOI ~ 0.4 Caprano CRISPRa Activation dCas9-VP64 BV-2 Microglial Cell Line response to virus 2 Log2FC p-Value ... |
2170 34529489 pubmed Martin TD (2021) 1-PMID34529489 7253 7253 Yes 480 MaGeCK Score Significance Score.4 (FDR) < 0.1 High Throughput Negative Selection Pool Timecourse 10 Doublings - - - Mouse druggable genome (Elledge, 2021) CRISPRn Knockout Cas9 4T1 Breast Adenocarcinoma Cell Line cell proliferation 5 Rank MaGeCK Sco... |
2171 34529489 pubmed Martin TD (2021) 2-PMID34529489 7253 7253 Yes 198 MaGeCK Score Significance Score.4 (FDR) < 0.1 High Throughput Negative Selection in vivo Implantation to Mouse Model - - - - Mouse druggable genome (Elledge, 2021) CRISPRn Knockout Cas9 4T1 Breast Adenocarcinoma Cell Line tumorigenicity 5 Rank MaGeC... |
2172 34529489 pubmed Martin TD (2021) 3-PMID34529489 7253 7253 Yes 282 MaGeCK Score Significance Score.4 (FDR) < 0.1 High Throughput Negative Selection in vivo Implantation to Mouse Model - SCID BALB/c host - - Mouse druggable genome (Elledge, 2021) CRISPRn Knockout Cas9 4T1 Breast Adenocarcinoma Cell Line tumorigenici... |
2173 34529489 pubmed Martin TD (2021) 4-PMID34529489 7253 7253 Yes 40 MaGeCK Score Significance Score.4 (FDR) < 0.1 High Throughput Positive Selection Pool Timecourse 10 Doublings - - - Mouse druggable genome (Elledge, 2021) CRISPRn Knockout Cas9 4T1 Breast Adenocarcinoma Cell Line cell proliferation 5 Rank MaGeCK Scor... |
2174 34529489 pubmed Martin TD (2021) 5-PMID34529489 7253 7253 Yes 100 MaGeCK Score Significance Score.4 (FDR) < 0.1 High Throughput Positive Selection in vivo Implantation to Mouse Model - - - - Mouse druggable genome (Elledge, 2021) CRISPRn Knockout Cas9 4T1 Breast Adenocarcinoma Cell Line tumorigenicity 5 Rank MaGeC... |
2175 34529489 pubmed Martin TD (2021) 6-PMID34529489 7253 7253 Yes 18 MaGeCK Score Significance Score.4 (FDR) < 0.1 High Throughput Positive Selection in vivo Implantation to Mouse Model - SCID BALB/c host - - Mouse druggable genome (Elledge, 2021) CRISPRn Knockout Cas9 4T1 Breast Adenocarcinoma Cell Line tumorigenicit... |
2176 34529489 pubmed Martin TD (2021) 7-PMID34529489 7253 7253 Yes 44 MaGeCK Score Significance Score.4 (FDR) < 0.1 High Throughput Negative Selection Pool Timecourse 10 Doublings - - - Mouse druggable genome (Elledge, 2021) CRISPRn Knockout Cas9 CT26 Colonic Cancer Cell Line cell proliferation 4 Rank Log2FC p-Value FD... |
2177 34529489 pubmed Martin TD (2021) 8-PMID34529489 7253 7253 Yes 44 MaGeCK Score Significance Score.4 (FDR) < 0.1 High Throughput Negative Selection in vivo Implantation to Mouse Model - - - - Mouse druggable genome (Elledge, 2021) CRISPRn Knockout Cas9 CT26 Colonic Cancer Cell Line tumorigenicity 4 Rank Log2FC p-Val... |
2178 34529489 pubmed Martin TD (2021) 9-PMID34529489 7253 7253 Yes 186 MaGeCK Score Significance Score.4 (FDR) < 0.1 High Throughput Negative Selection in vivo Implantation to Mouse Model - SCID BALB/c host - - Mouse druggable genome (Elledge, 2021) CRISPRn Knockout Cas9 CT26 Colonic Cancer Cell Line tumorigenicity 4 R... |
2179 34529489 pubmed Martin TD (2021) 10-PMID34529489 7253 7253 Yes 54 MaGeCK Score Significance Score.4 (FDR) < 0.1 High Throughput Positive Selection Pool Timecourse 10 Doublings - - - Mouse druggable genome (Elledge, 2021) CRISPRn Knockout Cas9 CT26 Colonic Cancer Cell Line cell proliferation 4 Rank Log2FC p-Value F... |
2180 34529489 pubmed Martin TD (2021) 11-PMID34529489 7253 7253 Yes 30 MaGeCK Score Significance Score.4 (FDR) < 0.1 High Throughput Positive Selection in vivo Implantation to Mouse Model - - - - Mouse druggable genome (Elledge, 2021) CRISPRn Knockout Cas9 CT26 Colonic Cancer Cell Line tumorigenicity 4 Rank Log2FC p-Va... |
2181 34529489 pubmed Martin TD (2021) 12-PMID34529489 7253 7253 Yes 41 MaGeCK Score Significance Score.4 (FDR) < 0.1 High Throughput Positive Selection in vivo Implantation to Mouse Model - SCID BALB/c host - - Mouse druggable genome (Elledge, 2021) CRISPRn Knockout Cas9 CT26 Colonic Cancer Cell Line tumorigenicity 4 R... |
2182 34529489 pubmed Martin TD (2021) 13-PMID34529489 472 472 Yes 47 EdgeR Score Significance Score.3 (FDR) < 0.1 High Throughput Positive and Negative Selection Pool Timecourse 10 Doublings - - - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout Cas9 185-3 MPNST Malignant Peripheral N... |
2183 34529489 pubmed Martin TD (2021) 14-PMID34529489 472 472 Yes 18 EdgeR Score Significance Score.3 (FDR) < 0.1 High Throughput Positive and Negative Selection in vivo Implantation to Mouse Model - Rag1-/- mice - - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout Cas9 185-3 MPNST Ma... |
2184 34529489 pubmed Martin TD (2021) 15-PMID34529489 472 472 Yes 21 EdgeR Score Significance Score.3 (FDR) < 0.1 High Throughput Positive and Negative Selection in vivo Implantation to Mouse Model - - - - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout Cas9 185-3 MPNST Malignant Per... |
2185 34529489 pubmed Martin TD (2021) 16-PMID34529489 471 471 Yes 58 EdgeR Score Significance Score.3 (FDR) < 0.1 High Throughput Positive and Negative Selection Pool Timecourse 10 Doublings - - - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout Cas9 B16 Melanoma Cell Line cell prolif... |
2186 34529489 pubmed Martin TD (2021) 17-PMID34529489 471 471 Yes 36 EdgeR Score Significance Score.3 (FDR) < 0.1 High Throughput Positive and Negative Selection in vivo Implantation to Mouse Model - Rag1-/- mice - - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout Cas9 B16 Melanoma C... |
2187 34529489 pubmed Martin TD (2021) 18-PMID34529489 471 471 Yes 23 EdgeR Score Significance Score.3 (FDR) < 0.1 High Throughput Positive and Negative Selection in vivo Implantation to Mouse Model - - - - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout Cas9 B16 Melanoma Cell Line tu... |
2188 34529489 pubmed Martin TD (2021) 19-PMID34529489 472 472 Yes 31 EdgeR Score Significance Score.3 (FDR) < 0.1 High Throughput Positive and Negative Selection Pool Timecourse 10 Doublings - - - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout Cas9 KP1233 Non-Small Cell Lung Cancer ... |
2189 34529489 pubmed Martin TD (2021) 20-PMID34529489 472 472 Yes 4 EdgeR Score Significance Score.3 (FDR) < 0.1 High Throughput Positive and Negative Selection in vivo Implantation to Mouse Model - Rag1-/- mice - - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout Cas9 KP1233 Non-Smal... |
2190 34529489 pubmed Martin TD (2021) 21-PMID34529489 472 472 Yes 0 EdgeR Score Significance Score.3 (FDR) < 0.1 High Throughput Positive and Negative Selection in vivo Implantation to Mouse Model - - - - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout Cas9 KP1233 Non-Small Cell Lung... |
2191 34529489 pubmed Martin TD (2021) 22-PMID34529489 472 472 Yes 13 MaGeCK Score Significance Score.3 (FDR) < 0.1 High Throughput Negative Selection Pool T cell exposure 6 Hours OT-I T cells 0.1 Ratio of effector cells/target cells - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout C... |
2192 34529489 pubmed Martin TD (2021) 23-PMID34529489 472 472 Yes 18 MaGeCK Score Significance Score.3 (FDR) < 0.1 High Throughput Positive Selection Pool T cell exposure 6 Hours OT-I T cells 0.1 Ratio of effector cells/target cells - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout C... |
2193 34529489 pubmed Martin TD (2021) 24-PMID34529489 472 472 Yes 2 MaGeCK Score Significance Score.3 (FDR) < 0.1 High Throughput Negative Selection Pool T cell exposure 6 Hours OT-I T cells 0.25 Ratio of effector cells/target cells - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout C... |
2194 34529489 pubmed Martin TD (2021) 25-PMID34529489 472 472 Yes 7 MaGeCK Score Significance Score.3 (FDR) < 0.1 High Throughput Positive Selection Pool T cell exposure 6 Hours OT-I T cells 0.25 Ratio of effector cells/target cells - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout C... |
2195 34529489 pubmed Martin TD (2021) 26-PMID34529489 472 472 Yes 5 MaGeCK Score Significance Score.3 (FDR) < 0.1 High Throughput Phenotype Screen Pool Cytokine exposure 16 Hours Interferon gamma 20.0 ng - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout Cas9 C57BL/6 mouse pancreas ce... |
2196 34529489 pubmed Martin TD (2021) 27-PMID34529489 472 472 Yes 3 MaGeCK Score Significance Score.3 (FDR) < 0.1 High Throughput Phenotype Screen Pool Timecourse 16 Hours - - - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout Cas9 C57BL/6 mouse pancreas cells expressing full-length o... |
2197 34529489 pubmed Martin TD (2021) 28-PMID34529489 472 472 Yes 9 MaGeCK Score Significance Score.3 (FDR) < 0.1 High Throughput Phenotype Screen Pool Cytokine exposure 16 Hours Interferon gamma 20.0 ng - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout Cas9 C57BL/6 mouse pancreas ce... |
2198 34529489 pubmed Martin TD (2021) 29-PMID34529489 472 472 Yes 40 MaGeCK Score Significance Score.3 (FDR) < 0.1 High Throughput Phenotype Screen Pool Timecourse 16 Hours - - - Mouse Tumor Suppressor Gene (TSG) targeted library (Elledge, 2021) CRISPRn Knockout Cas9 C57BL/6 mouse pancreas cells expressing full-length ... |
2211 36794958 pubmed Gilliland HN (2023) 1-PMID36794958 11702 11702 Yes 100 Robust-rank aggregation (RRA) Score Significance Score.1 (Rank) <= 100.0 High Throughput Phenotype Screen Pool Bacteria Exposure 4 Hours Mycobacterium abscessus 5.0 MOI - Brie (mouse) CRISPRn Knockout Cas9 iBMDM (immortalized bone marrow derive... |
2307 36396656 pubmed Liu Y (2022) 1-PMID36396656 19674 19674 Yes 1303 MaGeCK Score Significance Score.1 (Beta Score) > 0.643 OR Score.1 (Beta Score) < -0.575 High Throughput Positive and Negative Selection Pool Drug Exposure 12 Days Gemcitabine 20.0 nM - Brie (mouse) CRISPRn Knockout Cas9 4292 KRASG12D/p53R172H Pancre... |
2308 36396656 pubmed Liu Y (2022) 2-PMID36396656 19674 19674 Yes 3483 MaGeCK Score Significance Score.1 (Beta Score) >= 0.1188 OR Score.1 (Beta Score) < -0.1893 High Throughput Positive and Negative Selection Pool Drug Exposure 12 Days selinexor 0.33 µM - Brie (mouse) CRISPRn Knockout Cas9 4292 KRASG12D/p53R172H Pancr... |
2359 35804923 pubmed Yang H (2022) 1-PMID35804923 22507 22507 Yes 3 MaGeCK Score Significance Score.1 (MaGeCK Score) > 0.0 AND Score.2 (p-Value) < 0.05 AND Score.3 (FDR) < 0.05 High Throughput Positive Selection Pool Drug Exposure 15 Days Gemcitabine 50.0 nM = 0.3 GECKO v2 CRISPRn Knockout Cas9 TB32047 Pancreatic Cance... |
2372 38395437 pubmed Qian Z (2024) 1-PMID38395437 59 59 Yes 9 MaGeCK Score Significance Score.2 (p-Value) < 0.1 High Throughput Phenotype Screen in vivo Implantation to Mouse Model 10 Weeks - - = 0.3 CRISPRa targeted library based on Caprano sgRNAs (Zhao, 2024) CRISPRa Activation dCas9-VP64 BNL CL.2 Liver cell line tum... |
2403 36772830 pubmed Al Adhami H (2023) 1-PMID36772830 19673 19673 Yes 126 MaGeCK Score Significance Score.1 (p-Value) < 0.005 High Throughput Phenotype Screen Pool Timecourse 10 Days - - = 0.3 Brie (mouse) CRISPRn Knockout Cas9 Mouse Embryonic Stem Cell Embryonic Cell Line protein/peptide accumulation 2 p-Value Log2FC... |
2411 34879274 pubmed Zhao H (2021) 1-PMID34879274 2643 19674 No 2643 Log2 Fold Change (L2FC) All Significant - High Throughput Negative Selection in vivo Implantation to Mouse Model 7 Days - - ~ 0.5 Brie (mouse) CRISPRn Knockout Cas9 OT-I cells Cytotoxic T-lymphocyte (CD8+ T cells) cell proliferation 1 Log2FC - - - - 1... |
2412 34879274 pubmed Zhao H (2021) 2-PMID34879274 1555 19674 No 1555 Log2 Fold Change (L2FC) All Significant - High Throughput Negative Selection Pool Cytokine exposure 7 Days Interleukin-2 (IL-2) - ~ 0.5 Brie (mouse) CRISPRn Knockout Cas9 OT-I cells Cytotoxic T-lymphocyte (CD8+ T cells) cell proliferation 1 Log2FC - -... |
2429 40372436 pubmed Soriaga LB (2025) 2-PMID40372436 21189 21189 Yes 109 MaGeCK Score Significance Score.2 (FDR) < 0.05 OR Score.4 (FDR) < 0.05 High Throughput Positive and Negative Selection Pool Virus Exposure 48 Hours Virus: Influenza A (A/Puerto Rico/8/1934(H1N1) 1.0 MOI - Brie (mouse) CRISPRn Knockout Cas9 BV-2 M... |
2469 10.1101/2025.08.26.672429 prepub Fatimah J. Al Khazal (2025) 1-CUSTOM00000028 19648 19648 Yes 2171 MaGeCK Score Significance Score.1 (MAGeCK pos score) < 0.05 AND Score.2 (p-Value) < 0.05 OR Score.4 (MAGeCK neg score) < 0.05 AND Score.5 (p-Value) < 0.05 High Throughput Positive and Negative Selection Pool Timecour... |
2474 36476853 pubmed He B (2022) 1-PMID36476853 1146 1146 Yes 59 MaGeCK Score Significance Score.1 (Log2FC) > 0.58 AND Score.2 (p-Value) < 0.05 OR Score.1 (Log2FC) < -0.58 AND Score.2 (p-Value) < 0.05 High Throughput Phenotype Screen Pool Timecourse 7 Days - - = 0.3 MitoCarta2.0 CRISPRn Knockout Cas9 MEF Embryonic Fibr... |
2477 37059858 pubmed Ruan Y (2023) 1-PMID37059858 19674 19674 Yes 4342 MaGeCK Score Significance Score.2 (p-Value) < 0.05 OR Score.4 (p-Value) < 0.05 High Throughput Positive and Negative Selection Pool Other 14 Days Leukaemia inhibitory factors (LIF)/serum condition (L/S) - = 0.4 Brie (mouse) CRISPRn Knockout Cas9 R1 ... |
2488 39681701 pubmed Uijttewaal ECH (2024) 1-PMID39681701 20461 20461 Yes 477 CRISPR-StAR–MAGeCK analysis pipeline Score Significance Score.1 (Log2FC) < -3.0 AND Score.2 (RRA score) >= 10.0 High Throughput Negative Selection Pool Timecourse 14 Days - - = 0.25 CRISPRn library in CRISPR-StAR vector (Elling, 2024) CRISPRn... |
2490 39681701 pubmed Uijttewaal ECH (2024) 3-PMID39681701 538 538 Yes 29 CRISPR-StAR–MAGeCK analysis pipeline Score Significance Score.1 (Log2FC) < -1.5 OR Score.1 (Log2FC) > 1.0 High Throughput Positive and Negative Selection Pool Drug Exposure 14 Days dabrafenib 100.0 nM = 0.25 Targeted CRISPRn library in CRISPR-StAR... |
2491 39681701 pubmed Uijttewaal ECH (2024) 4-PMID39681701 538 538 Yes 19 CRISPR-StAR–MAGeCK analysis pipeline Score Significance Score.1 (Log2FC) < -1.5 OR Score.1 (Log2FC) > 1.0 High Throughput Positive and Negative Selection Pool Timecourse 14 Days - - = 0.25 Targeted CRISPRn library in CRISPR-StAR vector (Elling, 20... |
2492 39681701 pubmed Uijttewaal ECH (2024) 2-PMID39681701 20461 20461 Yes 515 CRISPR-StAR–MAGeCK analysis pipeline Column Significance - High Throughput Positive and Negative Selection Pool Implantation to Mouse Model 14 Days - - = 0.25 CRISPRn library in CRISPR-StAR vector (Elling, 2024) CRISPRn Knockout Cas9 YUMM1.7 ... |
2493 39681701 pubmed Uijttewaal ECH (2024) 5-PMID39681701 538 538 Yes 139 CRISPR-StAR–MAGeCK analysis pipeline Score Significance Score.1 (Log2FC) < -1.5 OR Score.1 (Log2FC) > 1.0 High Throughput Positive and Negative Selection Pool Implantation to Mouse Model 14 Days - - = 0.25 Targeted CRISPRn library in CRISPR-StAR ... |
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