screen_file string | organism string | perturbation string | gene string | cell string | phenotype string | hit int64 | benchmark_type string | prompt string | gene_context string |
|---|---|---|---|---|---|---|---|---|---|
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Lrr1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Lrr1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Lrr1 (leucine rich repeat protein 1)
Type: protein-coding
Summary: Predicted to be involved in intracellular signal transduction. Predicted to be located in nucleus. Orthologous to human LRR1 (leucine rich repeat protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Gene Ontolo... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Tmem126b | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Tmem126b in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Tmem126b (transmembrane protein 126B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial respiratory chain complex I assembly, mitochondrion organization, response to food; CC: membrane, mitochondrial membrane, mitochondrion
Pathways: Aerobic res... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Tbca | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Tbca in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Tbca (tubulin cofactor A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: post-chaperonin tubulin folding pathway, protein folding, tubulin complex assembly; MF: beta-tubulin binding, tubulin binding; CC: cytoplasm, cytoskeleton, microtubule, microtubule cytoskeleto... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Gm2897 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Gm2897 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Gm2897 (predicted gene 2897)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: K7N6T7
Entrez ID: 100040671 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Chmp2a | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Chmp2a in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Chmp2a (charged multivesicular body protein 2A)
Type: protein-coding
Summary: Predicted to enable phosphatidylcholine binding activity and protein domain specific binding activity. Predicted to be involved in several processes, including mitotic nuclear division; regulation of cell cycle process; ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ckap5 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ckap5 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ckap5 (cytoskeleton associated protein 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA transport, cell division, central nervous system myelin formation, centrosome cycle, centrosome duplication, cytoplasmic translation, dendritic spine maintenance, establish... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Sdhaf2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Sdhaf2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Sdhaf2 (succinate dehydrogenase complex assembly factor 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial electron transport, succinate to ubiquinone, mitochondrial respiratory chain complex II assembly, negative regulation of canonical Wnt signaling ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Eif3f | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Eif3f in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Eif3f (eukaryotic translation initiation factor 3, subunit F)
Type: protein-coding
Summary: Enables cysteine-type deubiquitinase activity and translation initiation factor binding activity. Contributes to translation initiation factor activity. Involved in translational initiation. Part of eukaryo... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | 2700062C07Rik | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of 2700062C07Rik in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: 2700062C07Rik (RIKEN cDNA 2700062C07 gene)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA processing, biological_process; CC: cellular_component, nucleus, ribonuclease MRP complex
Pathways:
UniProt: Q5XFZ0
Entrez ID: 68046 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Slc25a19 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Slc25a19 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Slc25a19 (solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: deoxynucleotide transport, thiamine diphosphate biosynthetic process, thiamine pyrophosphate transmembrane transport, thiami... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrpl53 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrpl53 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrpl53 (mitochondrial ribosomal protein L53)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, ribonucleoprotein complex, ribosome
Pathways: Metabolism of proteins, Mitochondr... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Eif3a | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Eif3a in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Eif3a (eukaryotic translation initiation factor 3, subunit A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: IRES-dependent viral translational initiation, cytoplasmic translational initiation, formation of cytoplasmic translation initiation complex, negative regul... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mfn2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mfn2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mfn2 (mitofusin 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: aerobic respiration, apoptotic process, autophagy, blastocyst formation, camera-type eye morphogenesis, intracellular distribution of mitochondria, mitochondrial calcium ion homeostasis, mitochondria... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Abce1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Abce1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Abce1 (ATP-binding cassette, sub-family E member 1)
Type: protein-coding
Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Cdkn2a | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Cdkn2a in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Cdkn2a (cyclin dependent kinase inhibitor 2A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: amyloid fibril formation, apoptotic process, apoptotic signaling pathway, autophagy of mitochondrion, cellular response to gamma radiation, cellular response to hydrogen pe... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Cad | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Cad in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Cad (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: 'de novo' UMP biosynthetic process, 'de novo' pyrimidine nucleobase biosynthetic process, UDP biosynthetic process, UTP biosyntheti... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Psmd13 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Psmd13 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Psmd13 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 13)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: meiosis I, ubiquitin-dependent protein catabolic process; MF: endopeptidase activity, structural molecule activity; CC: cytosol, nucleus, proteasome ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Cep55 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Cep55 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Cep55 (centrosomal protein 55)
Type: protein-coding
Summary: Predicted to enable identical protein binding activity. Predicted to be involved in cranial skeletal system development; establishment of protein localization; and midbody abscission. Located in intercellular bridge and midbody. Is expre... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Vps18 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Vps18 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Vps18 (VPS18 CORVET/HOPS core subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: autophagy, endosome organization, endosome to lysosome transport, intracellular protein transport, lysosome organization, negative regulation of intracellular estrogen receptor si... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ttc14 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ttc14 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ttc14 (tetratricopeptide repeat domain 14)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: nucleic acid binding, protein binding
Pathways:
UniProt: Q9CSP9
Entrez ID: 67120 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ptcd1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ptcd1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ptcd1 (pentatricopeptide repeat domain 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, tRNA 3'-end processing, tRNA processing; MF: tRNA binding; CC: mitochondrial matrix, mitochondrion
Pathways:
UniProt: Q8C2E4
... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Snx7 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Snx7 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Snx7 (sorting nexin 7)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: endocytic recycling, mitophagy, piecemeal microautophagy of the nucleus, positive regulation of autophagosome assembly, protein transport, reticulophagy; MF: lipid binding, phosphatidylinositol b... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Chmp3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Chmp3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Chmp3 (charged multivesicular body protein 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: autophagosome maturation, autophagy, cell division, endosome to lysosome transport, endosome transport via multivesicular body sorting pathway, late endosome to lysosome tr... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nudc | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nudc in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nudc (nudC nuclear distribution protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell division, establishment of organelle localization, mitotic metaphase chromosome alignment, mitotic spindle organization, nuclear migration, protein folding, response to pep... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Igf1r | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Igf1r in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Igf1r (insulin-like growth factor I receptor)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: adrenal gland development, amyloid-beta clearance, animal organ morphogenesis, axonogenesis, brain development, cell surface receptor protein tyrosine kinase signaling path... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Exosc3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Exosc3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Exosc3 (exosome component 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CUT catabolic process, DNA deamination, DNA metabolic process, RNA catabolic process, RNA processing, TRAMP-dependent tRNA surveillance pathway, U4 snRNA 3'-end processing, exonucleolytic t... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Cenpp | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Cenpp in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Cenpp (centromere protein P)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CENP-A containing chromatin assembly, biological_process, chromosome segregation; CC: chromosome, chromosome, centromeric region, inner kinetochore, nucleolus, nucleoplasm, nucleus
... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rps20 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rps20 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rps20 (ribosomal protein S20)
Type: protein-coding
Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encode... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Kti12 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Kti12 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Kti12 (KTI12 homolog, chromatin associated)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: ATP binding, molecular_function, nucleotide binding
Pathways:
UniProt: Q9D1R2
Entrez ID: 100087 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Srsf5 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Srsf5 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Srsf5 (serine and arginine-rich splicing factor 5)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Gigyf1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Gigyf1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Gigyf1 (GRB10 interacting GYF protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: insulin-like growth factor receptor signaling pathway; CC: cytosol, protein-containing complex
Pathways:
UniProt: Q99MR1
Entrez ID: 57330 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rrp36 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rrp36 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rrp36 (ribosomal RNA processing 36)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), rRNA processing, ribosomal small subunit biogenesis, ribosome biogenesis; CC: 90S preribosom... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Tomm70a | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Tomm70a in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Tomm70a (translocase of outer mitochondrial membrane 70A)
Type: protein-coding
Summary: Predicted to enable mitochondrion targeting sequence binding activity and molecular adaptor activity. Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in several p... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pik3c2a | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pik3c2a in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pik3c2a (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: autophagosome organization, cell migration, cellular response to starvation, endocytosis, exocytosis, lipid metabolic process, macroaut... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Sdhc | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Sdhc in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Sdhc (succinate dehydrogenase complex, subunit C, integral membrane protein)
Type: protein-coding
Summary: Predicted to enable heme binding activity. Predicted to be involved in mitochondrial electron transport, succinate to ubiquinone. Located in mitochondrion. Part of respiratory chain complex I... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Fus | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Fus in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Fus (fused in sarcoma)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, amyloid fibril formation, gene expression, mRNA stabilization, membraneless organelle assembly, positive regulation of DNA-templated transcription, positive regulation of double-str... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Acly | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Acly in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Acly (ATP citrate lyase)
Type: protein-coding
Summary: Enables ATP citrate synthase activity. Predicted to be involved in acetyl-CoA biosynthetic process and carboxylic acid metabolic process. Located in mitochondrion. Is active in cytosol. Is expressed in several structures, including alimentary ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rapgef1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rapgef1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rapgef1 (Rap guanine nucleotide exchange factor (GEF) 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Rap protein signal transduction, Ras protein signal transduction, blood vessel development, cell-cell adhesion, cellular response to cAMP, cellular response to n... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pnpt1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pnpt1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pnpt1 (polyribonucleotide nucleotidyltransferase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA catabolic process, RNA import into mitochondrion, RNA processing, cellular response to interferon-beta, cellular response to oxidative stress, liver regeneration,... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Bri3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Bri3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Bri3 (brain protein I3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: identical protein binding; CC: cytoplasm, lysosomal membrane, lysosome, membrane, perinuclear region of cytoplasm
Pathways: Immune System, Innate Immune System, Neutrophil degranulation... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nsun4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nsun4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nsun4 (NOL1/NOP2/Sun domain family, member 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial RNA catabolic process, mitochondrial RNA modification, rRNA methylation, tRNA methylation; MF: RNA methyltransferase activity, mRNA (cytidine-5-)-methyltransf... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Bcl7a | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Bcl7a in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Bcl7a (B cell CLL/lymphoma 7A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin remodeling, motor behavior, negative regulation of cell differentiation, neuron projection arborization, positive regulation of cell population proliferation, positive regulatio... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Gm15127 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Gm15127 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Gm15127 (predicted gene 15127)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: E9Q1L3, B1AVZ5
Entrez ID: 434866 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Med13 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Med13 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Med13 (mediator complex subunit 13)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cholesterol homeostasis, negative regulation of transcription by RNA polymerase II, positive regulation of DNA-templated transcription, positive regulation of transcription by RNA po... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mbip | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mbip in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mbip (MAP3K12 binding inhibitory protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, positive regulation of JNK cascade, positive regulation of gene expression, regulation of DNA-templated transcripti... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Sptlc1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Sptlc1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Sptlc1 (serine palmitoyltransferase, long chain base subunit 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ceramide biosynthetic process, lipid metabolic process, positive regulation of lipophagy, regulation of fat cell apoptotic process, sphinganine biosynthet... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Tmprss4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Tmprss4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Tmprss4 (transmembrane protease, serine 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of growth rate, positive regulation of viral entry into host cell, protein processing, proteolysis, regulation of gene expression, response to wounding; MF... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Lig3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Lig3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Lig3 (ligase III, DNA, ATP-dependent)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA biosynthetic process, DNA damage response, DNA recombination, DNA repair, DNA replication, base-excision repair, cell division, double-strand break repair, double-strand break ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Scd3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Scd3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Scd3 (stearoyl-coenzyme A desaturase 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: fatty acid biosynthetic process, fatty acid metabolic process, lipid metabolic process, monounsaturated fatty acid biosynthetic process, response to fatty acid, unsaturated fatty... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Atp1b3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Atp1b3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Atp1b3 (ATPase, Na+/K+ transporting, beta 3 polypeptide)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: intracellular potassium ion homeostasis, intracellular sodium ion homeostasis, membrane repolarization, metal ion transport, monoatomic ion transport, positive r... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Dhx16 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Dhx16 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Dhx16 (DEAH-box helicase 16)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, antiviral innate immune response, immune system process, innate immune response, mRNA processing, mRNA splicing, via spliceosome; MF: ATP binding, ATP-dependent activity, acti... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Plrg1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Plrg1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Plrg1 (pleiotropic regulator 1)
Type: protein-coding
Summary: Acts upstream of or within positive regulation of G1/S transition of mitotic cell cycle and protein localization to nucleus. Predicted to be located in fibrillar center; nuclear membrane; and nuclear speck. Predicted to be part of DNA r... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ifna12 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ifna12 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ifna12 (interferon alpha 12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: B cell activation involved in immune response, T cell activation involved in immune response, adaptive immune response, defense response, defense response to virus, humoral immune response,... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Edc3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Edc3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Edc3 (enhancer of mRNA decapping 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: P-body assembly, deadenylation-independent decapping of nuclear-transcribed mRNA; MF: RNA binding, identical protein binding, mRNA binding; CC: P-body, cytoplasm, cytoplasmic ribonuc... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Cmpk1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Cmpk1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Cmpk1 (cytidine/uridine monophosphate kinase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: 'de novo' pyrimidine nucleobase biosynthetic process, CDP biosynthetic process, UDP biosynthetic process, dCDP biosynthetic process, dUDP biosynthetic process, nucleobase... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Cdh2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Cdh2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Cdh2 (cadherin 2)
Type: protein-coding
Summary: This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion. The encoded preproprotein undergoes proteolytic processing to generate a mature protein. Mice lacking the encoded protein exhibit severe ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrpl45 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrpl45 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrpl45 (mitochondrial ribosomal protein L45)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, ribonucleoprotein ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Gstcd | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Gstcd in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Gstcd (glutathione S-transferase, C-terminal domain containing)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, respiratory system development, response to lipopolysaccharide; MF: molecular_function, protein binding; CC: cytoplasm
Pathwa... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Actr10 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Actr10 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Actr10 (ARP10 actin-related protein 10)
Type: protein-coding
Summary: Acts upstream of or within microtubule-based movement. Part of dynactin complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Prpf18 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Prpf18 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Prpf18 (pre-mRNA processing factor 18)
Type: protein-coding
Summary: Predicted to be involved in generation of catalytic spliceosome for second transesterification step and negative regulation of protein metabolic process. Predicted to be located in nuclear speck. Predicted to be part of U2-type p... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pkm | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pkm in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pkm (pyruvate kinase, muscle)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: canonical glycolysis, cellular response to insulin stimulus, chromatin remodeling, glucose metabolic process, glycolytic process, positive regulation of cytoplasmic translation, positive r... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Tbcc | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Tbcc in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Tbcc (tubulin-specific chaperone C)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: post-chaperonin tubulin folding pathway, protein folding, tubulin complex assembly; MF: GTPase activity, tubulin binding; CC: cytoplasm, cytosol, endoplasmic reticulum, photoreceptor... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Usp8 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Usp8 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Usp8 (ubiquitin specific peptidase 8)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Ras protein signal transduction, cellular response to dexamethasone stimulus, cellular response to nerve growth factor stimulus, endosome organization, mitotic cytokinesis, negativ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ssbp1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ssbp1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ssbp1 (single-stranded DNA binding protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA replication, DNA-templated DNA replication, mitochondrion organization, positive regulation of mitochondrial DNA replication, protein homotetramerization; MF: DNA bindi... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Chchd3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Chchd3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Chchd3 (coiled-coil-helix-coiled-coil-helix domain containing 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cristae formation, inner mitochondrial membrane organization, mitochondrial fusion; MF: molecular adaptor activity, phosphatase binding, protein binding;... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Tectb | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Tectb in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Tectb (tectorin beta)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: extracellular matrix structural constituent, protein binding; CC: cell periphery, cell surface, extracellular matrix, extracellular region, extracellular space, membrane, plasma membrane, side of ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ccl19 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ccl19 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ccl19 (C-C motif chemokine ligand 19)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CCL19-activated CCR7 signaling pathway, T cell costimulation, antimicrobial humoral immune response mediated by antimicrobial peptide, cell maturation, cell migration, cellular res... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Sp2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Sp2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Sp2 (Sp2 transcription factor)
Type: protein-coding
Summary: This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc fin... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Dcaf13 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Dcaf13 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Dcaf13 (DDB1 and CUL4 associated factor 13)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: decidualization, epigenetic programming in the zygotic pronuclei, female gamete generation, maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Gm17019 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Gm17019 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Gm17019 (predicted gene 17019)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: K7N6W5
Entrez ID: 66773 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Serpine1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Serpine1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Serpine1 (serine (or cysteine) peptidase inhibitor, clade E, member 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to transforming growth factor beta stimulus, cellula... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Yae1d1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Yae1d1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Yae1d1 (Yae1 domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein maturation; CC: cellular_component, cytoplasm, nucleus
Pathways:
UniProt: A0A1Y7VLX4, Q9DAY6
Entrez ID: 67008 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Paqr5 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Paqr5 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Paqr5 (progestin and adipoQ receptor family member V)
Type: protein-coding
Summary: Predicted to enable signaling receptor activity. Predicted to be involved in oogenesis. Predicted to be located in plasma membrane. Is expressed in bladder; late tubule; urinary system; and urothelium of bladder. O... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Tmem186 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Tmem186 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Tmem186 (transmembrane protein 186)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial respiratory chain complex I assembly; CC: membrane, mitochondrial inner membrane, mitochondrion
Pathways: Aerobic respiration and respiratory electron transpor... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Dna2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Dna2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Dna2 (DNA replication helicase/nuclease 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA double-strand break processing, DNA repair, DNA replication, DNA replication checkpoint signaling, DNA replication, Okazaki fragment processing, DNA r... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Jun | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Jun in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Jun (jun proto-oncogene)
Type: protein-coding
Summary: Enables chromatin binding activity and transcription cis-regulatory region binding activity. Involved in cellular response to anisomycin and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processe... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Smu1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Smu1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Smu1 (smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome, regulation of alternative mRNA splicing, via spliceosome; CC: U2-type precatalytic spliceo... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Cherp | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Cherp in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Cherp (calcium homeostasis endoplasmic reticulum protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA processing, intracellular calcium ion homeostasis, negative regulation of cell population proliferation, positive regulation of calcineurin-NFAT signaling c... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Gtpbp4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Gtpbp4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Gtpbp4 (GTP binding protein 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), negative regulation of DNA replication, negative regulation of G2/M transition of mitotic cell cy... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Abcf2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Abcf2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Abcf2 (ATP-binding cassette, sub-family F member 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: ATP binding, ATP hydrolysis activity, nucleotide binding, protein binding
Pathways:
UniProt: Q99LE6
Entrez ID: 27407 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Sptlc2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Sptlc2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Sptlc2 (serine palmitoyltransferase, long chain base subunit 2)
Type: protein-coding
Summary: This gene encodes a long chain base subunit of serine palmitoyltransferase. The enzyme, serine palmitoyltransferase, consists of two different subunits, and is the key enzyme in sphingolipid biosynthesis.... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Irf9 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Irf9 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Irf9 (interferon regulatory factor 9)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: defense response to protozoan, dendritic cell differentiation, immune system process, lymphocyte activation involved in immune response, lymphocyte differentiation, myeloid cell di... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Sdhd | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Sdhd in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Sdhd (succinate dehydrogenase complex, subunit D, integral membrane protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to hypoxia, mitochondrial electron transport, succinate to ubiquinone, proton motive force-driven mitochondrial ATP synthes... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ten1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ten1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ten1 (TEN1 telomerase capping complex subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of telomere maintenance via telomerase; MF: DNA binding, single-stranded DNA binding, telomerase inhibitor activity, telomeric DNA binding; CC: CST com... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Tprkb | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Tprkb in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Tprkb (Tp53rk binding protein)
Type: protein-coding
Summary: Predicted to enable protein kinase binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to be located in cytoplasm. Predicted to be part of EKC/KEOPS complex. Predicted to be active in cyt... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Sirt6 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Sirt6 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Sirt6 (sirtuin 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, Ras protein signal transduction, base-excision repair, cardiac muscle cell differentiation, cellular response to angiotensin... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Med4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Med4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Med4 (mediator complex subunit 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, positive regulation of DNA-templated transcription, positive regulation of transcription elongation by RNA polymerase II, positive reg... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ipo11 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ipo11 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ipo11 (importin 11)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: intracellular protein transport, nucleocytoplasmic transport, protein import into nucleus, protein transport, ribosomal protein import into nucleus; MF: nuclear import signal receptor activity, prot... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrpl19 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrpl19 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrpl19 (mitochondrial ribosomal protein L19)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrial riboso... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rabggta | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rabggta in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rabggta (Rab geranylgeranyl transferase, a subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: Rab geranylgeranyltransferase activity, prenyltransferase activity, protein geranylgeranyltransferase activity, protein prenyltransferase activity, small GTPase bindi... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rpl7l1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rpl7l1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rpl7l1 (ribosomal protein L7-like 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: blastocyst formation, maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); MF: RNA binding, structural constituent of ribosome; CC: cytosol, cyt... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Coq4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Coq4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Coq4 (coenzyme Q4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ubiquinone biosynthetic process; MF: 4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity, carboxy-lyase activity, lyase activity, metal ion binding, molecular_function; CC: extrinsic comp... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Camk1d | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Camk1d in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Camk1d (calcium/calmodulin-dependent protein kinase ID)
Type: protein-coding
Summary: Predicted to enable calcium/calmodulin-dependent protein kinase activity and calmodulin binding activity. Involved in positive regulation of neuron projection development and positive regulation of neutrophil che... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ints5 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ints5 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ints5 (integrator complex subunit 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA polymerase II transcription initiation surveillance, snRNA 3'-end processing, snRNA processing; CC: INTAC complex, cytoplasm, cytosol, integrator complex, membrane, nuclear memb... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Lsm12 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Lsm12 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Lsm12 (LSM12 homolog)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: RNA binding, molecular_function; CC: cellular_component, cytoplasm
Pathways:
UniProt: Q9D0R8
Entrez ID: 268490 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Dctn5 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Dctn5 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Dctn5 (dynactin 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: aorta development, coronary vasculature development, ventricular septum development; CC: centrosome, chromosome, chromosome, centromeric region, cytoplasm, cytoskeleton, dynactin complex, kinetochore... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rpa2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rpa2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rpa2 (replication protein A2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, DNA replication, base-excision repair, double-strand break repair via homologous recombination, mismatch repair, mitotic G1 DNA damage c... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pbrm1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pbrm1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pbrm1 (polybromo 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: blastocyst formation, blood vessel remodeling, cardiac vascular smooth muscle cell development, chromatin organization, chromatin remodeling, epicardium-derived cardiac endothelial cell differentiat... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Dhx38 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Dhx38 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Dhx38 (DEAH-box helicase 38)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome; MF: 3'-5' RNA helicase activity, ATP binding, ATP-dependent activity, acting on RNA, RNA binding, RNA helicase activity, helic... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Riok1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Riok1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Riok1 (RIO kinase 1)
Type: protein-coding
Summary: This gene encodes a member of the RIO family of atypical serine protein kinases. A similar protein in humans is a component of the protein arginine methyltransferase 5 complex that specifically recruits the RNA-binding protein nucleolin as a methy... |
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