screen_file string | organism string | perturbation string | gene string | cell string | phenotype string | hit int64 | benchmark_type string | prompt string | gene_context string |
|---|---|---|---|---|---|---|---|---|---|
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rprd1b | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rprd1b in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rprd1b (regulation of nuclear pre-mRNA domain containing 1B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA polymerase II promoter clearance, mRNA 3'-end processing, positive regulation of cell population proliferation, positive regulation of transcription by R... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Cdk4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Cdk4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Cdk4 (cyclin dependent kinase 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G1/S transition of mitotic cell cycle, cell division, cellular response to interleukin-4, cellular response to ionomycin, cellular response to lipopolysaccharide, cellular response to p... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Vmn2r42 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Vmn2r42 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Vmn2r42 (vomeronasal 2, receptor 42)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane
Pathways:
UniProt: D3YZ9... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Kdm2a | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Kdm2a in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Kdm2a (lysine (K)-specific demethylase 2A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin organization, chromatin remodeling, circadian regulation of gene expression, double-strand break repair via nonhomologous end joining, embryonic organ morphogenesis,... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Krtap5-4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Krtap5-4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Krtap5-4 (keratin associated protein 5-4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: cellular_component, cytosol, intermediate filament, keratin filament
Pathways: Developmental Biology, Keratinization
UniProt: Q62220
Entrez ID: 50775 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mybl2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mybl2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mybl2 (myeloblastosis oncogene-like 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to leukemia inhibitory factor, mitotic cell cycle, mitotic spindle assembly, positive regulation of neuron apoptotic process, positive regulation of transcriptio... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Lonp1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Lonp1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Lonp1 (lon peptidase 1, mitochondrial)
Type: protein-coding
Summary: Enables several functions, including ATP hydrolysis activity; ATP-dependent peptidase activity; and DNA binding activity. Acts upstream of or within negative regulation of insulin receptor signaling pathway; proteolysis; and regu... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrap | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrap in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrap (melanocortin 2 receptor accessory protein)
Type: protein-coding
Summary: Predicted to enable identical protein binding activity; melanocortin receptor binding activity; and signaling receptor regulator activity. Acts upstream of or within brown fat cell differentiation. Predicted to be locat... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Elac2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Elac2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Elac2 (elaC ribonuclease Z 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial tRNA 3'-end processing, tRNA processing; MF: 3'-tRNA processing endoribonuclease activity, endonuclease activity, hydrolase activity, metal ion binding, nuclease activity, tR... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ncl | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ncl in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ncl (nucleolin)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: angiogenesis, cellular response to epidermal growth factor stimulus, cellular response to leukemia inhibitory factor, cellular response to lipopolysaccharide, endocytosis, negative regulation of apoptot... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ep300 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ep300 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ep300 (E1A binding protein p300)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: B cell differentiation, DNA repair-dependent chromatin remodeling, N-terminal peptidyl-lysine acetylation, TORC1 signaling, TORC2 signaling, animal organ morphogenesis, apoptotic proces... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrps2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrps2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrps2 (mitochondrial ribosomal protein S2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial ribosome assembly, mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial small ribosoma... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Kntc1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Kntc1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Kntc1 (kinetochore associated 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell division, mitotic sister chromatid segregation, mitotic spindle assembly checkpoint signaling, protein localization to kinetochore involved in kinetochore assembly; CC: RZZ complex... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Exosc5 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Exosc5 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Exosc5 (exosome component 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA deamination, RNA catabolic process, RNA processing, U4 snRNA 3'-end processing, defense response to virus, mRNA catabolic process, nuclear mRNA surveillance, poly(A)-dependent snoRNA 3'... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Gm3488 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Gm3488 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Gm3488 (predicted gene, 3488)
Type: protein-coding
Summary: predicted gene, 3488
Gene Ontology:
Pathways:
UniProt: M0QW81
Entrez ID: 100041735 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Snrpf | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Snrpf in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Snrpf (small nuclear ribonucleoprotein polypeptide F)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome, protein-RNA complex assembly, spliceosomal snRNP assembly; MF: RNA binding; CC: SMN-Sm protein comple... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ndufb9 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ndufb9 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ndufb9 (NADH:ubiquinone oxidoreductase subunit B9)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: aerobic respiration, mitochondrial electron transport, NADH to ubiquinone, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner me... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rps23 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rps23 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rps23 (ribosomal protein S23)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, maintenance of translational fidelity, ribosomal small subunit biogenesis, stress granule assembly, translation; MF: protein binding, structural constituent of rib... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Cryzl1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Cryzl1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Cryzl1 (crystallin zeta like 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: identical protein binding, oxidoreductase activity; CC: early endosome, endosome
Pathways:
UniProt: Q921W4
Entrez ID: 66609 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rabggtb | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rabggtb in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rabggtb (Rab geranylgeranyl transferase, b subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: endoplasmic reticulum to Golgi vesicle-mediated transport, protein geranylgeranylation; MF: Rab geranylgeranyltransferase activity, catalytic activity, isoprenoid bin... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nhlrc2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nhlrc2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nhlrc2 (NHL repeat containing 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: cytoplasm, cytosol
Pathways: Hemostasis, Platelet activation, signaling and aggregation, Platelet degranulation , Response to elevated platelet cytosolic Ca2+, arsenate detoxif... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Eif4h | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Eif4h in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Eif4h (eukaryotic translation initiation factor 4H)
Type: protein-coding
Summary: This gene encodes eukaryotic translation initiation factor 4H (eIF4H) that plays a critical role in the process of protein synthesis. The encoded protein is an RNA-binding protein that, in concert with other translat... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nme6 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nme6 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nme6 (NME/NM23 nucleoside diphosphate kinase 6)
Type: protein-coding
Summary: Predicted to enable nucleoside diphosphate kinase activity. Predicted to be involved in negative regulation of cell growth and negative regulation of mitotic nuclear division. Located in mitochondrion. Is expressed in se... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rhod | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rhod in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rhod (ras homolog family member D)
Type: protein-coding
Summary: Enables GTP binding activity and protein kinase binding activity. Involved in regulation of actin cytoskeleton organization and regulation of focal adhesion assembly. Acts upstream of or within several processes, including actin fila... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nup188 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nup188 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nup188 (nucleoporin 188)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA export from nucleus, mRNA transport, nucleocytoplasmic transport, protein import into nucleus, protein transport; MF: structural constituent of nuclear pore; CC: nuclear envelope, nuclear p... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Fads2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Fads2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Fads2 (fatty acid desaturase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: alpha-linolenic acid metabolic process, arachidonate metabolite production involved in inflammatory response, fatty acid biosynthetic process, fatty acid derivative biosynthetic process,... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rpn2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rpn2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rpn2 (ribophorin II)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein N-linked glycosylation, protein glycosylation; MF: protein binding, ribosome binding; CC: autophagosome membrane, endoplasmic reticulum, endoplasmic reticulum membrane, membrane, nuclear bo... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Usp16 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Usp16 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Usp16 (ubiquitin specific peptidase 16)
Type: protein-coding
Summary: Enables histone H2A deubiquitinase activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in several structures, inc... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Zbtb14 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Zbtb14 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Zbtb14 (zinc finger and BTB domain containing 14)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cardiac septum development, coronary vasculature development, heart valve development, kidney development, negative regulation of DNA-templated transcription, negative ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Lrrc10 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Lrrc10 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Lrrc10 (leucine rich repeat containing 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cardiac muscle cell development; MF: actin binding, alpha-actinin binding; CC: cytoskeleton, mitochondrion, myofibril, nucleus, sarcomere
Pathways:
UniProt:... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Vmn1r11 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Vmn1r11 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Vmn1r11 (vomeronasal 1 receptor 11)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromone ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Sec22b | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Sec22b in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Sec22b (SEC22 homolog B, vesicle trafficking protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: endoplasmic reticulum to Golgi vesicle-mediated transport, negative regulation of autophagosome assembly, positive regulation of protein catabolic process, protein ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pgam1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pgam1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pgam1 (phosphoglycerate mutase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: canonical glycolysis, gluconeogenesis, glyceraldehyde-3-phosphate biosynthetic process, glycolytic process; MF: bisphosphoglycerate mutase activity, catalytic activity, hydrolase activ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pa2g4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pa2g4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pa2g4 (proliferation-associated 2G4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of DNA-templated transcription, negative regulation of apoptotic process, positive regulation of cell differentiation, rRNA processing, regulation of translation... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Sel1l | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Sel1l in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Sel1l (sel-1 suppressor of lin-12-like (C. elegans))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ERAD pathway, Notch signaling pathway, protein secretion, protein transport, response to endoplasmic reticulum stress, retrograde protein transport, ER to cytosol, t... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrpl12 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrpl12 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrpl12 (mitochondrial ribosomal protein L12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial transcription, mitochondrial translation, positive regulation of DNA-templated transcription, translation; MF: mRNA binding, structural constituent of ribosome... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | C4b | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of C4b in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: C4b (complement C4B (Chido blood group))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: complement activation, complement activation, GZMK pathway, complement activation, classical pathway, complement activation, lectin pathway, immune system process, immunoglobuli... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nfx1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nfx1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nfx1 (nuclear transcription factor, X-box binding 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of MHC class II biosynthetic process, negative regulation of transcription by RNA polymerase II, protein autoubiquitination; MF: DNA binding, DNA... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pacsin1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pacsin1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pacsin1 (protein kinase C and casein kinase substrate in neurons 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: actin filament organization, cytoskeleton organization, endocytosis, negative regulation of endocytosis, neuron development, neuron projection morphog... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pofut2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pofut2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pofut2 (protein O-fucosyltransferase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: fucose metabolic process, mesoderm formation, positive regulation of protein folding, protein O-linked glycosylation via fucose, protein glycosylation, regulation of epithelial t... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Trim34b | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Trim34b in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Trim34b (tripartite motif-containing 34B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: defense response to virus, innate immune response, protein ubiquitination, regulation of gene expression; MF: identical protein binding, metal ion binding, transferase activity... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Timmdc1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Timmdc1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Timmdc1 (translocase of inner mitochondrial membrane domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, mitochondrial respiratory chain complex I assembly; CC: membrane, mitochondrial membrane, mitochondrion, nucleoplasm
... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | H2-T3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of H2-T3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: H2-T3 (histocompatibility 2, T region locus 3)
Type: protein-coding
Summary: Predicted to enable several functions, including beta-2-microglobulin binding activity; peptide antigen binding activity; and signaling receptor binding activity. Predicted to be involved in several processes, including a... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Yeats4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Yeats4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Yeats4 (YEATS domain containing 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin organization, chromatin remodeling, positive regulation of DNA-templated transcription, positive regulation of double-strand break repair via homologous recombination, regul... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Zfp534 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Zfp534 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Zfp534 (zinc finger protein 534)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Spc24 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Spc24 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Spc24 (SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: attachment of spindle microtubules to kinetochore, cell division, chromosome segregation, mitotic spindle assembly checkpoint signaling; CC: N... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Axin1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Axin1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Axin1 (axin 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Wnt signaling pathway, apoptotic process, axial mesoderm development, axial mesoderm formation, beta-catenin destruction complex assembly, canonical Wnt signaling pathway, cell development, cytoplasmic m... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Donson | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Donson in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Donson (downstream neighbor of SON)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage checkpoint signaling, DNA replication, mitotic DNA replication checkpoint signaling, mitotic G2 DNA damage checkpoint signaling, nuclear DNA replication, replication fork ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rps28 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rps28 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rps28 (ribosomal protein S28)
Type: protein-coding
Summary: A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation; maturation of SSU-rRNA; and ribosomal small subunit assembly. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in seve... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ssrp1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ssrp1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ssrp1 (structure specific recognition protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, DNA replication, nucleosome assembly, nucleosome disassembly, regulation of chromatin organization; MF: DNA binding, chromatin binding, ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rhox3e | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rhox3e in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rhox3e (reproductive homeobox 3E)
Type: protein-coding
Summary: Orthologous to human RHOXF2B (Rhox homeobox family member 2B). [provided by Alliance of Genome Resources, Apr 2025]
Gene Ontology:
Pathways:
UniProt: V9GX94, Q4TU90, V9GXY5, V9GXK5, V9GWU0, V9GXD0, V9GXQ1
... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Gnl3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Gnl3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Gnl3 (guanine nucleotide binding protein nucleolar 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of miRNA transcription, positive regulation of protein localization to chromosome, telomeric region, positive regulation of protein sumoylation,... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Tmem201 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Tmem201 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Tmem201 (transmembrane protein 201)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: angiogenesis, centrosome localization, fibroblast migration, nuclear envelope organization, nuclear migration, nuclear migration along microtubule, positive regulation of endothelial... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pwp2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pwp2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pwp2 (PWP2 periodic tryptophan protein homolog (yeast))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), ribosomal small subunit assembly, ribosomal small subunit biogenesis; CC... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ddx52 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ddx52 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ddx52 (DExD box helicase 52)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: maturation of SSU-rRNA; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase activity, hydrolase activity, nucleic acid binding, nucleotide binding; CC: nu... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Eif2s2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Eif2s2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Eif2s2 (eukaryotic translation initiation factor 2 subunit 2 beta)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translational initiation, formation of translation preinitiation complex, in utero embryonic development, male germ cell proliferation, mal... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mbd3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mbd3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mbd3 (methyl-CpG binding domain protein 3)
Type: protein-coding
Summary: This gene encodes a member of the MBD family of nuclear proteins that contain a methyl-CpG binding domain (MBD). The encoded protein is a component of the nucleosome remodeling and histone deacetylation (NuRD) complex. Deleti... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ubl5 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ubl5 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ubl5 (ubiquitin-like 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mRNA splicing, via spliceosome, protein modification process; CC: cytoplasm, nucleus
Pathways: Metabolism of RNA, Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing, mRNA Sp... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rps25 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rps25 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rps25 (ribosomal protein S25)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, rRNA processing, ribosomal small subunit biogenesis; MF: structural constituent of ribosome; CC: cytoplasm, cytosol, cytosolic ribosome, cytosolic small ribosomal ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Yrdc | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Yrdc in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Yrdc (yrdC domain containing (E.coli))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of transport, regulation of translational fidelity, tRNA threonylcarbamoyladenosine modification; MF: L-threonylcarbamoyladenylate synthase, double-stranded RN... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Asns | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Asns in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Asns (asparagine synthetase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: L-asparagine biosynthetic process, amino acid biosynthetic process, asparagine biosynthetic process, cellular response to glucose starvation, negative regulation of apoptotic process, posit... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pdcd10 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pdcd10 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pdcd10 (programmed cell death 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Golgi reassembly, angiogenesis, apoptotic process, cellular response to anoxia, cellular response to leukemia inhibitory factor, endothelium development, establishment of Golgi localiz... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pfdn5 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pfdn5 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pfdn5 (prefoldin 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA polymerase I assembly, RNA polymerase II core complex assembly, RNA polymerase III assembly, negative regulation of DNA-templated transcription, negative regulation of amyloid fibril formation, ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrpl4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrpl4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrpl4 (mitochondrial ribosomal protein L4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, ribonuc... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Sds | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Sds in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Sds (serine dehydratase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: L-serine catabolic process, amino acid metabolic process, gluconeogenesis, lipid metabolic process, protein-containing complex assembly, pyruvate biosynthetic process, small molecule biosynthet... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrps33 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrps33 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrps33 (mitochondrial ribosomal protein S33)
Type: protein-coding
Summary: Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; liver; salivary gland; and spleen. Orthologous to human MRPS33 (mitochon... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Frs2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Frs2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Frs2 (fibroblast growth factor receptor substrate 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: anterior/posterior axis specification, embryo, cell surface receptor protein tyrosine kinase signaling pathway, cellular response to fibroblast growth factor stimulu... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Krtap10-4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Krtap10-4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Krtap10-4 (keratin associated protein 10-4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: identical protein binding, molecular_function; CC: cellular_component, cytosol, intermediate filament, keratin filament
Pathways: Developmental Biology, Keratinizati... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Vmn1r79 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Vmn1r79 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Vmn1r79 (vomeronasal 1 receptor 79)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Isca1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Isca1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Isca1 (iron-sulfur cluster assembly 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: iron-sulfur cluster assembly, protein maturation; MF: 2 iron, 2 sulfur cluster binding, iron-sulfur cluster binding, metal ion binding; CC: cytoplasm, mitochondrial [4Fe-4S] assem... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Zfp652 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Zfp652 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Zfp652 (zinc finger protein 652)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, metal ion binding, zinc ion binding
Pathways:
... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Atxn2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Atxn2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Atxn2 (ataxin 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: P-body assembly, cerebellar Purkinje cell differentiation, homeostasis of number of cells, negative regulation of multicellular organism growth, negative regulation of receptor internalization, neuromu... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Psma1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Psma1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Psma1 (proteasome subunit alpha 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: immune system process, negative regulation of inflammatory response to antigenic stimulus, proteasome-mediated ubiquitin-dependent protein catabolic process, proteolysis involved in p... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Slc25a32 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Slc25a32 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Slc25a32 (solute carrier family 25, member 32)
Type: protein-coding
Summary: Enables FAD transmembrane transporter activity. Involved in mitochondrial FAD transmembrane transport. Located in mitochondrion. Is expressed in embryo; metencephalon floor plate; and skeletal muscle. Orthologous to human... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Dhrs7b | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Dhrs7b in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Dhrs7b (dehydrogenase/reductase 7B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: adipose tissue development, brown fat cell differentiation, ether lipid biosynthetic process, fat cell differentiation, inflammatory response, negative regulation of DNA-templated tr... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rpl32 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rpl32 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rpl32 (ribosomal protein L32)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to dexamethasone stimulus, cytoplasmic translation, liver regeneration, translation, translation at postsynapse, translation at presynapse; MF: structural constituent of ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Trmu | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Trmu in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Trmu (tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: tRNA processing, tRNA wobble position uridine thiolation; MF: ATP binding, RNA binding, nucleotide binding, sulfurtransferase activity, tRNA binding, tR... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Zbtb26 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Zbtb26 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Zbtb26 (zinc finger and BTB domain containing 26)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, regulation of cytokine production, regulation of immune system process; MF: DNA binding, DNA-binding transcri... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Kctd4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Kctd4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Kctd4 (potassium channel tetramerisation domain containing 4)
Type: protein-coding
Summary: Predicted to be involved in protein homooligomerization. Is expressed in cerebral cortex subventricular zone; cortical plate; midbrain; and periaqueductal grey. Orthologous to human KCTD4 (potassium channel... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Gramd4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Gramd4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Gramd4 (GRAM domain containing 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, negative regulation of toll-like receptor 9 signaling pathway, positive regulation of apoptotic process; CC: endoplasmic reticulum, endoplasmic reticulum membrane, m... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rrp15 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rrp15 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rrp15 (ribosomal RNA processing 15 homolog)
Type: protein-coding
Summary: This gene encodes a protein similar to budding yeast Rrp15p. Rrp15p is a component of pre-60S ribosomal particles in budding yeast, and is required for the early maturation steps of the 60S subunit. The mouse genome contains... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Foxn2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Foxn2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Foxn2 (forkhead box N2)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity and cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within skeletal muscle cell differentiation. Predicted to be located in nucleoplasm. Predicted t... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Fanca | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Fanca in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Fanca (Fanconi anemia, complementation group A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, female gonad development, interstrand cross-link repair, male gonad development, male meiotic nuclear division, regulation of CD40 signal... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrps18b | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrps18b in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrps18b (mitochondrial ribosomal protein S18B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: cell junction, mitochondrial inner membrane, mitochondrial small ribosomal subunit, mit... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mis12 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mis12 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mis12 (MIS12 kinetochore complex component)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: attachment of mitotic spindle microtubules to kinetochore, attachment of spindle microtubules to kinetochore, cell division, chromosome segregation, kinetochore assembly, mit... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mycbp | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mycbp in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mycbp (MYC binding protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of DNA-templated transcription, regulation of DNA-templated transcription; MF: transcription coactivator activity; CC: cytoplasm, mitochondrion, nucleoplasm, nucleus
... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rbm27 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rbm27 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rbm27 (RNA binding motif protein 27)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: RNA binding, metal ion binding, nucleic acid binding, zinc ion binding; CC: cytoplasm, nuclear speck, nucleus
Pathways: Metabolism of RNA, Nuclear RNA decay
UniPro... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ufm1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ufm1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ufm1 (ubiquitin-fold modifier 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: brain development, negative regulation of apoptotic process, negative regulation of protein import into nucleus, protein K69-linked ufmylation, protein ufmylation, regulation of intrace... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Tex19.1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Tex19.1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Tex19.1 (testis expressed gene 19.1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell differentiation, cell proliferation involved in embryonic placenta development, homologous chromosome pairing at meiosis, in utero embryonic development, male gonad development... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mical2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mical2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mical2 (microtubule associated monooxygenase, calponin and LIM domain containing 2)
Type: protein-coding
Summary: Enables several functions, including NAD(P)H oxidase H2O2-forming activity; actin binding activity; and mitogen-activated protein kinase binding activity. Involved in actin filament de... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Kdm1a | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Kdm1a in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Kdm1a (lysine (K)-specific demethylase 1A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA repair-dependent chromatin remodeling, cell differentiation, cellular response to UV, cellular response to gamma radiation, chromatin organization, epigenetic regulation o... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mecr | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mecr in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mecr (mitochondrial trans-2-enoyl-CoA reductase)
Type: protein-coding
Summary: Predicted to enable enoyl-[acyl-carrier-protein] reductase (NADPH) activity; nuclear receptor binding activity; and signaling receptor binding activity. Predicted to be involved in fatty acid metabolic process. Located ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Psma5 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Psma5 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Psma5 (proteasome subunit alpha 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: proteasome-mediated ubiquitin-dependent protein catabolic process, proteolysis involved in protein catabolic process, ubiquitin-dependent protein catabolic process; CC: cytoplasm, cyt... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Farsb | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Farsb in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Farsb (phenylalanyl-tRNA synthetase, beta subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: phenylalanyl-tRNA aminoacylation, protein heterotetramerization, translation; MF: ATP binding, RNA binding, aminoacyl-tRNA ligase activity, ligase activity, magnesium ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Slbp | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Slbp in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Slbp (stem-loop binding protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cap-dependent translational initiation, mRNA 3'-end processing by stem-loop binding and cleavage, mRNA processing, mRNA transport; MF: RNA binding, histone pre-mRNA stem-loop binding, i... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Asb3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Asb3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Asb3 (ankyrin repeat and SOCS box-containing 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, establishment or maintenance of cell polarity, intracellular signal transduction, protein ubiquitination, regulation of Wnt signaling pathway
... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Aco2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Aco2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Aco2 (aconitase 2, mitochondrial)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: citrate metabolic process, isocitrate metabolic process, tricarboxylic acid cycle; MF: 3 iron, 4 sulfur cluster binding, 4 iron, 4 sulfur cluster binding, aconitate hydratase activity,... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mup9 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mup9 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mup9 (major urinary protein 9)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: P02762
Entrez ID: 100038948 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nop2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nop2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nop2 (NOP2 nucleolar protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA methylation, RNA processing, blastocyst formation, maturation of LSU-rRNA, methylation, rRNA base methylation, rRNA processing, regulation of signal transduction by p53 class mediator,... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mdn1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mdn1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mdn1 (midasin AAA ATPase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ribosomal large subunit assembly, ribosome biogenesis; MF: ATP binding, ATP hydrolysis activity, molecular_function, nucleotide binding; CC: cytosol, intermediate filament cytoskeleton, nucl... |
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