screen_file string | organism string | perturbation string | gene string | cell string | phenotype string | hit int64 | benchmark_type string | prompt string | gene_context string |
|---|---|---|---|---|---|---|---|---|---|
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Polr3f | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Polr3f in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Polr3f (polymerase (RNA) III (DNA directed) polypeptide F)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: defense response to virus, immune system process, innate immune response, positive regulation of innate immune response, positive regulation of interferon-beta... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ppan | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ppan in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ppan (peter pan homolog)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), rRNA processing, regulation of cell growth by extracellular stimulus; MF: rRNA binding; CC: nucleolus, ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Alyref | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Alyref in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Alyref (Aly/REF export factor)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA export from nucleus, RNA folding, RNA splicing, mRNA export from nucleus, mRNA processing, mRNA transport; MF: C5-methylcytidine-containing RNA reader activity, RNA binding, RNA foldi... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nup62 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nup62 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nup62 (nucleoporin 62)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA export from nucleus, cell migration, cell surface receptor signaling pathway, cellular senescence, centriole assembly, centrosome cycle, mRNA transport, mitotic centrosome separation, mitotic... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrpl52 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrpl52 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrpl52 (mitochondrial ribosomal protein L52)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, nucle... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Wdr82 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Wdr82 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Wdr82 (WD repeat domain containing 82)
Type: protein-coding
Summary: Enables chromatin binding activity and lncRNA binding activity. Involved in RNA catabolic process and negative regulation of DNA-templated transcription. Acts upstream of or within gene expression. Located in nucleus. Is expresse... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rps12 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rps12 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rps12 (ribosomal protein S12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, maintenance of translational fidelity, positive regulation of canonical Wnt signaling pathway, ribosomal small subunit biogenesis, translation, translation at post... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Abca2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Abca2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Abca2 (ATP-binding cassette, sub-family A member 2)
Type: protein-coding
Summary: Predicted to enable several functions, including ATP binding activity; ceramide floppase activity; and endopeptidase regulator activity. Involved in several processes, including regulation of intracellular cholestero... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nek8 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nek8 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nek8 (NIMA (never in mitosis gene a)-related expressed kinase 8)
Type: protein-coding
Summary: This gene encodes a NIMA-related kinase. Members of this serine/threonine protein kinase family are structurally-related to NIMA (never in mitosis, gene A) which controls mitotic signaling in Aspergillus... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | R3hdm1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of R3hdm1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: R3hdm1 (R3H domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: molecular_function, nucleic acid binding
Pathways:
UniProt: E9Q9Q2, Q80ZH9, B9EHE8, Q3URW7, A0A087WPF0, A0A087WQI5, A0A087WQF6, A0A087WRE1, A0A087WP65
Entrez ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Fars2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Fars2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Fars2 (phenylalanine-tRNA synthetase 2, mitochondrial)
Type: protein-coding
Summary: Predicted to enable phenylalanine-tRNA ligase activity and tRNA binding activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation and tRNA processing. Located in mitochondrion. Is expressed in several... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ppp1r8 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ppp1r8 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ppp1r8 (protein phosphatase 1, regulatory subunit 8)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, cell population proliferation, mRNA processing; MF: DNA binding, RNA binding, RNA endonuclease activity, mRNA binding, molecular function inhibitor act... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Alas1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Alas1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Alas1 (aminolevulinic acid synthase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to insulin stimulus, erythrocyte development, heme A biosynthetic process, heme B biosynthetic process, heme biosynthetic process, hemoglobin biosynthetic proces... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Cct8 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Cct8 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Cct8 (chaperonin containing TCP1 subunit 8)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: binding of sperm to zona pellucida, positive regulation of telomere maintenance via telomerase, protein folding, protein stabilization; MF: ATP binding, ATP hydrolysis activi... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mapkap1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mapkap1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mapkap1 (mitogen-activated protein kinase associated protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: TORC2 signaling, cellular response to insulin stimulus, cellular response to nutrient levels, cytoskeleton organization, insulin receptor signaling pathwa... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Phf21a | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Phf21a in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Phf21a (PHD finger protein 21A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin organization, negative regulation of transcription by RNA polymerase II, suckling behavior; MF: DNA binding, chromatin binding, metal ion binding, zinc ion binding; CC: DNA rep... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Timm9 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Timm9 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Timm9 (translocase of inner mitochondrial membrane 9)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein insertion into mitochondrial inner membrane, protein transport; MF: membrane insertase activity, metal ion binding, protein homodimerization activity, prote... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Smc1a | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Smc1a in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Smc1a (structural maintenance of chromosomes 1A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, cell division, chromosome organization, meiotic cell cycle, mitotic spindle assembly, response to DNA damage checkpoint signaling, respo... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Sf3b6 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Sf3b6 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Sf3b6 (splicing factor 3B, subunit 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, blastocyst formation, mRNA processing, mRNA splicing, via spliceosome; MF: RNA binding, mRNA binding, nucleic acid binding; CC: U12-type spliceosomal complex, U2-type... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nutf2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nutf2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nutf2 (nuclear transport factor 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mRNA transport, negative regulation of vascular endothelial growth factor production, nucleocytoplasmic transport, positive regulation of protein import into nucleus, protein export f... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Eif4ebp3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Eif4ebp3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Eif4ebp3 (eukaryotic translation initiation factor 4E binding protein 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of translation, negative regulation of translational initiation, regulation of translation; MF: eukaryotic initiation factor ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Glrx5 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Glrx5 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Glrx5 (glutaredoxin 5)
Type: protein-coding
Summary: This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron-sulfur clusters, which are required for normal iron homeostasis. Mutations in the human gene are associated with autosomal rec... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nhp2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nhp2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nhp2 (NHP2 ribonucleoprotein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: rRNA processing, rRNA pseudouridine synthesis, ribosome biogenesis, snRNA pseudouridine synthesis, snoRNA guided rRNA pseudouridine synthesis, telomere maintenance via telomerase; MF: RNA ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rsl24d1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rsl24d1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rsl24d1 (ribosomal L24 domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ribosomal large subunit biogenesis, ribosome biogenesis; CC: nucleolus, nucleoplasm, nucleus
Pathways: Coronavirus disease - COVID-19 - Mus musculus (mouse), Ribosom... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Psmg4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Psmg4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Psmg4 (proteasome (prosome, macropain) assembly chaperone 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, proteasome assembly; MF: molecular_function, protein binding, protein-containing complex binding; CC: cytosol, protein-containing complex... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Atg9a | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Atg9a in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Atg9a (autophagy related 9A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: autophagosome assembly, autophagy, bone morphogenesis, innate immune response, lipid transport, mitophagy, negative regulation of interferon-beta production, negative regulation of macropha... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Seh1l | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Seh1l in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Seh1l (SEH1-like (S. cerevisiae)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: attachment of mitotic spindle microtubules to kinetochore, cell division, cellular response to amino acid starvation, cellular response to nutrient levels, chromosome segregation, defen... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Caap1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Caap1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Caap1 (caspase activity and apoptosis inhibitor 1)
Type: protein-coding
Summary: Predicted to be involved in negative regulation of apoptotic process. Orthologous to human CAAP1 (caspase activity and apoptosis inhibitor 1). [provided by Alliance of Genome Resources, Jul 2025]
Gene Ontolog... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Supt20 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Supt20 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Supt20 (SPT20 SAGA complex component)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: gastrulation, positive regulation of DNA-templated transcription, positive regulation of gluconeogenesis, positive regulation of transcription by RNA polymerase II, regulation of D... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Plekhh3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Plekhh3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Plekhh3 (pleckstrin homology domain containing, family H (with MyTH4 domain) member 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q8VCE9
Entrez ID: 217198 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pdss2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pdss2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pdss2 (prenyl (solanesyl) diphosphate synthase, subunit 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cerebellum development, isoprenoid biosynthetic process, lipid metabolic process, regulation of body fluid levels, ubiquinone biosynthetic process; MF: all-tra... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrpl14 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrpl14 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrpl14 (mitochondrial ribosomal protein L14)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, translation; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, ribonucleoprotein complex, ribosome
... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ddx54 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ddx54 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ddx54 (DEAD box helicase 54)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA metabolic process, RNA processing, negative regulation of DNA-templated transcription, rRNA processing; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, hel... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Eif3e | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Eif3e in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Eif3e (eukaryotic translation initiation factor 3, subunit E)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translational initiation, formation of cytoplasmic translation initiation complex, nuclear-transcribed mRNA catabolic process, nonsense-mediated... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Wdr75 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Wdr75 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Wdr75 (WD repeat domain 75)
Type: protein-coding
Summary: Predicted to enable RNA binding activity. Predicted to be involved in positive regulation of rRNA processing; positive regulation of transcription by RNA polymerase I; and ribosomal small subunit biogenesis. Predicted to be part of small-su... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nol6 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nol6 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nol6 (nucleolar protein family 6 (RNA-associated))
Type: protein-coding
Summary: Predicted to enable RNA binding activity. Predicted to be involved in rRNA processing; ribosomal small subunit biogenesis; and tRNA export from nucleus. Located in condensed nuclear chromosome and nucleolus. Is expres... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nol12 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nol12 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nol12 (nucleolar protein 12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: RNA binding, identical protein binding, rRNA binding, single-stranded DNA binding; CC: cytoplasm, nucleolus, nucleus
Pathways:
UniProt: Q8BG17
Entrez ID: 97961 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Slc38a2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Slc38a2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Slc38a2 (solute carrier family 38, member 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: L-glutamine import across plasma membrane, L-proline import across plasma membrane, L-serine import across plasma membrane, L-serine transport, acidic amino acid transport, ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pop7 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pop7 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pop7 (processing of precursor 7, ribonuclease P family, (S. cerevisiae))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA processing, rRNA processing, tRNA 5'-leader removal, tRNA processing; MF: nucleic acid binding, ribonuclease P RNA binding, ribonuclease P ac... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mcrs1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mcrs1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mcrs1 (microspherule protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, chromatin organization, chromatin remodeling, negative regulation of telomere maintenance via telomere lengthening, positive regulatio... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rai1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rai1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rai1 (retinoic acid induced 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: circadian regulation of gene expression, negative regulation of multicellular organism growth, positive regulation of DNA-templated transcription, regulation of transcription by RNA polym... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Hnrnpl | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Hnrnpl in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Hnrnpl (heterogeneous nuclear ribonucleoprotein L)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to amino acid starvation, mRNA processing, negative regulation of DNA-templated transcription, negative regulation of mRNA splicing, via spliceosome,... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Get4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Get4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Get4 (golgi to ER traffic protein 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ERAD pathway, maintenance of unfolded protein, post-translational protein targeting to endoplasmic reticulum membrane, protein insertion into ER membrane, regulation of protein stab... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Bptf | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Bptf in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Bptf (bromodomain PHD finger transcription factor)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: anterior/posterior pattern specification, brain development, cellular response to nerve growth factor stimulus, chromatin organization, chromatin remodeling, embryonic... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nup43 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nup43 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nup43 (nucleoporin 43)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell division, chromosome segregation, mRNA transport, nucleocytoplasmic transport, protein transport; CC: chromosome, chromosome, centromeric region, cytosol, kinetochore, nuclear envelope, nucl... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Zdhhc16 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Zdhhc16 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Zdhhc16 (zinc finger, DHHC domain containing 16)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, apoptotic process, eye development, fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment, heart developm... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Fgfr1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Fgfr1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Fgfr1 (fibroblast growth factor receptor 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: angiogenesis, auditory receptor cell development, biomineral tissue development, blood vessel morphogenesis, brain development, branching involved in salivary gland morphogen... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Lrrc69 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Lrrc69 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Lrrc69 (leucine rich repeat containing 69)
Type: protein-coding
Summary: Predicted to be involved in intracellular signal transduction. Orthologous to human LRRC69 (leucine rich repeat containing 69). [provided by Alliance of Genome Resources, Jul 2025]
Gene Ontology:
Pathways: ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Imp4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Imp4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Imp4 (IMP4, U3 small nucleolar ribonucleoprotein)
Type: protein-coding
Summary: Predicted to enable snoRNA binding activity. Predicted to be involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to be located in fibrillar center. Predicted to be part of Mpp10 complex and sm... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Wdr73 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Wdr73 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Wdr73 (WD repeat domain 73)
Type: protein-coding
Summary: Predicted to be involved in cytoplasmic microtubule organization; negative regulation of apoptotic process; and nucleus organization. Predicted to colocalize with cleavage furrow; cytosol; and spindle pole. Human ortholog(s) of this gene im... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Xrn2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Xrn2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Xrn2 (5'-3' exoribonuclease 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA recombination, DNA repair, DNA-templated transcription termination, RNA metabolic process, hippocampus development, mRNA processing, microtubule-based process, neuron differentiation,... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Surf6 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Surf6 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Surf6 (surfeit gene 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ribosomal large subunit biogenesis, ribosomal small subunit biogenesis, ribosome assembly, ribosome biogenesis; MF: DNA binding, RNA binding, molecular condensate scaffold activity; CC: chromosom... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Itgb1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Itgb1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Itgb1 (integrin beta 1 (fibronectin receptor beta))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CD40 signaling pathway, G1/S transition of mitotic cell cycle, angiogenesis, axon extension, basement membrane organization, bicellular tight junction assembly, calci... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ccdc86 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ccdc86 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ccdc86 (coiled-coil domain containing 86)
Type: protein-coding
Summary: Located in nucleus. Is expressed in urinary system. Orthologous to human CCDC86 (coiled-coil domain containing 86). [provided by Alliance of Genome Resources, Apr 2025]
Gene Ontology: BP: chromosome segregation, mitot... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Wdr27 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Wdr27 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Wdr27 (WD repeat domain 27)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q8C5V5
Entrez ID: 71682 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Myt1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Myt1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Myt1 (myelin transcription factor 1)
Type: protein-coding
Summary: This gene is a member of the myelin transcription factor 1 gene family. The encoded protein, a zinc finger DNA-binding protein, is involved in regulation of oligodendrocyte differentiation and proliferation in the developing centra... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ppp4r2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ppp4r2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ppp4r2 (protein phosphatase 4, regulatory subunit 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, hematopoietic progenitor cell differentiation, mRNA processing, regulation of double-strand break repair, regulation of double-strand break repair via ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Vac14 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Vac14 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Vac14 (Vac14 homolog (S. cerevisiae))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: phosphatidylinositol biosynthetic process, regulation of postsynaptic neurotransmitter receptor internalization, response to osmotic stress; MF: identical protein binding, kinase a... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nckap1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nckap1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nckap1 (NCK-associated protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Rac protein signal transduction, apical protein localization, basal protein localization, cell migration, cell migration involved in gastrulation, cell morphogenesis, cell projection a... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | BC005624 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of BC005624 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: BC005624 (cDNA sequence BC005624)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, chromosome segregation, mRNA cis splicing, via spliceosome, mRNA processing, mRNA splicing, via spliceosome, regulation of homologous chromosome segregation; MF: RNA bind... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Brix1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Brix1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Brix1 (BRX1, biogenesis of ribosomes)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: rRNA processing, ribosomal large subunit assembly, ribosome biogenesis; MF: RNA binding, rRNA binding; CC: chromosome, nucleolus, nucleus
Pathways:
UniProt: Q9DC... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Olig2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Olig2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Olig2 (oligodendrocyte transcription factor 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: axon development, central nervous system neuron differentiation, myelination, negative regulation of neuron differentiation, negative regulation of transcription by RNA po... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Syt3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Syt3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Syt3 (synaptotagmin III)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell differentiation, chemical synaptic transmission, exocytosis, positive regulation of dendrite extension, positive regulation of vesicle fusion, regulation of calcium ion-dependent exocytosi... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pdss1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pdss1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pdss1 (prenyl (solanesyl) diphosphate synthase, subunit 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: isoprenoid biosynthetic process, lipid metabolic process, ubiquinone biosynthetic process; MF: all-trans-decaprenyl-diphosphate synthase activity, all-trans-no... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Atp6v0b | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Atp6v0b in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Atp6v0b (ATPase, H+ transporting, lysosomal V0 subunit B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: monoatomic ion transport, proton transmembrane transport; MF: P-type proton-exporting transporter activity, proton transmembrane transporter activity, proton-tr... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Coq5 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Coq5 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Coq5 (coenzyme Q5 methyltransferase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: methylation, ubiquinone biosynthetic process; MF: 2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity, methyltransferase activity, transferase activity; CC: extrinsic ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Supt6 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Supt6 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Supt6 (SPT6, histone chaperone and transcription elongation factor)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, blastocyst formation, mRNA processing, mRNA transport, nucleobase-containing compound metabolic process, nucleosome organization, positi... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Uba5 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Uba5 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Uba5 (ubiquitin-like modifier activating enzyme 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: erythrocyte differentiation, megakaryocyte differentiation, neuromuscular process, protein K69-linked ufmylation, protein ufmylation, regulation of intracellular estro... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Syvn1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Syvn1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Syvn1 (synovial apoptosis inhibitor 1, synoviolin)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ERAD pathway, immature B cell differentiation, in utero embryonic development, negative regulation of T-helper 1 type immune response, negative regulation of endoplasm... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Magoh | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Magoh in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Magoh (mago homolog, exon junction complex core component)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, female gamete generation, mRNA export from nucleus, mRNA processing, mRNA splicing, via spliceosome, mRNA transport, nuclear-transcribed mRNA cat... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Nars2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Nars2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Nars2 (asparaginyl-tRNA synthetase 2 (mitochondrial)(putative))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: asparaginyl-tRNA aminoacylation, tRNA aminoacylation for protein translation, translation; MF: ATP binding, aminoacyl-tRNA ligase activity, asparagine-tRN... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrpl3 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrpl3 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrpl3 (mitochondrial ribosomal protein L3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, ribonuc... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Usp36 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Usp36 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Usp36 (ubiquitin specific peptidase 36)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin organization, chromatin remodeling, negative regulation of macroautophagy, nucleolus organization, protein deubiquitination, protein stabilization, proteolysis, regulat... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrpl15 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrpl15 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrpl15 (mitochondrial ribosomal protein L15)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to leukemia inhibitory factor, mitochondrial translation, mitochondrion organization, translation; MF: structural constituent of ribosome; CC: large riboso... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Btaf1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Btaf1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Btaf1 (B-TFIID TATA-box binding protein associated factor 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of DNA-templated transcription; MF: ATP binding, ATP hydrolysis activity, ATP-dependent activity, acting on DNA, DNA binding, TBP-class p... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Gpr160 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Gpr160 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Gpr160 (G protein-coupled receptor 160)
Type: protein-coding
Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrpl54 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrpl54 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrpl54 (mitochondrial ribosomal protein L54)
Type: protein-coding
Summary: Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including brain; brown fat; early conceptus; gonad; ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ei24 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ei24 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ei24 (etoposide induced 2.4 mRNA)
Type: protein-coding
Summary: Predicted to enable importin-alpha family protein binding activity. Acts upstream of or within several processes, including cellular response to UV-C; intrinsic apoptotic signaling pathway in response to DNA damage; and negative regul... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Chmp6 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Chmp6 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Chmp6 (charged multivesicular body protein 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: autophagosome maturation, autophagy, late endosome to lysosome transport, late endosome to vacuole transport via multivesicular body sorting pathway, membrane fission, midb... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ppp1r10 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ppp1r10 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ppp1r10 (protein phosphatase 1, regulatory subunit 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA polymerase II promoter clearance, negative regulation of cardiac muscle cell apoptotic process, negative regulation of mitotic DNA damage checkpoint, negative ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Fdxr | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Fdxr in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Fdxr (ferredoxin reductase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cholesterol metabolic process, lipid metabolic process, steroid biosynthetic process, steroid metabolic process, ubiquinone biosynthetic process; MF: ferredoxin-NADP+ reductase activity, oxi... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Lin54 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Lin54 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Lin54 (lin-54 DREAM MuvB core complex component)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: nucleosome organization, regulation of DNA-templated transcription; MF: DNA binding, metal ion binding, minor groove of adenine-thymine-rich DNA binding, transcription r... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Trmt6 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Trmt6 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Trmt6 (tRNA methyltransferase 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mRNA processing, tRNA methylation, tRNA processing; CC: nucleus, tRNA (m1A) methyltransferase complex
Pathways:
UniProt: Q8CE96
Entrez ID: 66926 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Gm13057 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Gm13057 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Gm13057 (predicted gene 13057)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, negative regulation of DNA-templated transcription, negative regulation of apoptotic process, negative regulation of cell differentiation, positive regulation of cell ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Itga6 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Itga6 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Itga6 (integrin alpha 6)
Type: protein-coding
Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are transmembrane receptors involved cell adhesion and signaling, and they are subdivided based on the heterodimer formation of alpha and beta chains. This pro... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Cdk7 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Cdk7 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Cdk7 (cyclin dependent kinase 7)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, RNA polymerase II promoter clearance, RNA polymerase II transcription initiation surveillance, cell division, positive regulation of transcription by RN... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ints6 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ints6 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ints6 (integrator complex subunit 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA polymerase II transcription initiation surveillance, protein localization to chromatin, snRNA 3'-end processing, snRNA processing, transcription by RNA polymerase II, transcript... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Slc29a4 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Slc29a4 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Slc29a4 (solute carrier family 29 (nucleoside transporters), member 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: adenosine transport, cellular detoxification, dopamine transport, dopamine uptake, epinephrine transport, epinephrine uptake, export across plasma ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Cox15 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Cox15 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Cox15 (cytochrome c oxidase assembly protein 15)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytochrome complex assembly, heme A biosynthetic process, heme biosynthetic process; MF: heme A synthase activity, metal ion binding, oxidoreductase activity, oxidoreduc... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Polr3c | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Polr3c in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Polr3c (polymerase (RNA) III (DNA directed) polypeptide C)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA-templated transcription, defense response to virus, immune system process, innate immune response, positive regulation of innate immune response, positive ... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rtcb | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rtcb in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rtcb (RNA 2',3'-cyclic phosphate and 5'-OH ligase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA processing, in utero embryonic development, placenta development, tRNA processing, tRNA splicing, via endonucleolytic cleavage and ligation; MF: GTP binding, RNA l... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Rexo2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Rexo2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Rexo2 (RNA exonuclease 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA metabolic process, mitochondrial RNA surveillance, nucleobase-containing compound metabolic process; MF: 3'-5' exonuclease activity, 3'-5'-DNA exonuclease activity, 3'-5'-RNA exonuclease a... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Ddx10 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Ddx10 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Ddx10 (DEAD box helicase 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: anterior head development, rRNA processing; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase activity, hydrolase activity, nucleic acid binding, nucleo... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Wars2 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Wars2 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Wars2 (tryptophanyl tRNA synthetase 2 (mitochondrial))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial tryptophanyl-tRNA aminoacylation, positive regulation of angiogenesis, tRNA aminoacylation for protein translation, translation, tryptophanyl-tRNA am... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mvk | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mvk in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mvk (mevalonate kinase)
Type: protein-coding
Summary: This gene encodes mevalonate kinase, a key enzyme involved in the biosynthesis of cholesterol and non-sterol isoprenes. The complete lack of encoded protein is lethal to mouse embryos. Mice lacking one allele of this gene exhibit increased leve... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Pga5 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Pga5 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Pga5 (pepsinogen 5, group I)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: proteolysis; MF: aspartic-type endopeptidase activity, hydrolase activity, peptidase activity; CC: cellular_component, extracellular region
Pathways: Protein digestion and absorpti... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Clp1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Clp1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Clp1 (CLP1, cleavage and polyadenylation factor I subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RISC complex assembly, RNA processing, cerebellar cortex development, global gene silencing by mRNA cleavage, mRNA 3'-end processing, mRNA processing, tRNA pro... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Adamdec1 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Adamdec1 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Adamdec1 (ADAM-like, decysin 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell differentiation, extracellular matrix organization, inflammatory response, proteolysis, tissue remodeling, wound healing; MF: hydrolase activity, metal ion binding, metalloendopepti... |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Gm10408 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Gm10408 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Gm10408 (predicted gene 10408)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: K7N693
Entrez ID: 100041840 |
SCREEN_18_HITS_ONLY_FOR_INVERSE.tsv | mouse | knockout | Mrps17 | NG2-3112 mouse glioblastoma cells | decreased sensitivity to gliocidin and subsequently glioblastoma cell survival | 1 | difficult | Does knockout of Mrps17 in NG2-3112 mouse glioblastoma cells causally result in decreased sensitivity to gliocidin and subsequently glioblastoma cell survival? | Gene: Mrps17 (mitochondrial ribosomal protein S17)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, translation; MF: RNA binding, rRNA binding, structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial small ribosomal su... |
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