screen_file string | organism string | perturbation string | gene string | cell string | phenotype string | hit int64 | benchmark_type string | prompt string | gene_context string |
|---|---|---|---|---|---|---|---|---|---|
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Uros | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Uros in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Uros (uroporphyrinogen III synthase)
Type: protein-coding
Summary: The protein encoded by this gene is the fourth enzyme in the heme biosynthesis pathway. It converts hydroxymethylbilane to uroporphyrinogen III, a cyclic tetrapyrrole. This enzyme is defective in the autosomal recessive disorder co... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mrpl55 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mrpl55 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mrpl55 (mitochondrial ribosomal protein L55)
Type: protein-coding
Summary: Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. O... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cdc45 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cdc45 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cdc45 (cell division cycle 45)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA replication, DNA replication initiation, double-strand break repair via break-induced replication, mitotic DNA replication preinitiation complex assembly; MF: DNA replication origin b... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Setdb1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Setdb1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Setdb1 (SET domain, bifurcated 1)
Type: protein-coding
Summary: Enables DNA binding activity; histone H3K9 methyltransferase activity; and promoter-specific chromatin binding activity. Involved in DNA methylation-dependent constitutive heterochromatin formation; negative regulation of single stran... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Memo1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Memo1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Memo1 (mediator of cell motility 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: regulation of microtubule-based process
Pathways: ERBB2 Regulates Cell Motility, Signal Transduction, Signaling by ERBB2, Signaling by Receptor Tyrosine Kinases
Uni... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cpox | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cpox in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cpox (coproporphyrinogen oxidase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: establishment or maintenance of transmembrane electrochemical gradient, heme A biosynthetic process, heme B biosynthetic process, heme biosynthetic process, porphyrin-containing compou... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl28 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl28 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl28 (ribosomal protein L28)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: structural constituent of ribosome; CC: cell body, cytoplasm, cytoplasmic ribonucleoprotein... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Atic | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Atic in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Atic (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase)
Type: protein-coding
Summary: Enables IMP cyclohydrolase activity and phosphoribosylaminoimidazolecarboxamide formyltransferase activity. Involved in purine ribonucleoside monophosphate biosynthetic process. ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pdcd11 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pdcd11 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pdcd11 (programmed cell death 11)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA processing, rRNA processing; MF: NF-kappaB binding, RNA binding, nucleic acid binding; CC: cytosol, nucleolus, nucleus, small-subunit processome
Pathways: Major pathway of... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Uqcr10 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Uqcr10 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Uqcr10 (ubiquinol-cytochrome c reductase, complex III subunit X)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular respiration, mitochondrial electron transport, ubiquinol to cytochrome c; CC: membrane, mitochondrial inner membrane, mitochondrion, respiratory... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rcc1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rcc1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rcc1 (regulator of chromosome condensation 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G1/S transition of mitotic cell cycle, cell division, chromosome segregation, mitotic spindle organization, regulation of mitotic cell cycle, regulation of mitotic nuclear ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Exosc1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Exosc1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Exosc1 (exosome component 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA catabolic process, RNA processing, rRNA processing; MF: RNA binding, nucleic acid binding, protein binding; CC: cytoplasm, cytoplasmic exosome (RNase complex), cytosol, exosome (RNase c... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Smc5 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Smc5 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Smc5 (structural maintenance of chromosomes 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, cell division, cellular senescence, chromosome condensation, chromosome organization, chromosome segregation, double-st... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Grwd1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Grwd1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Grwd1 (glutamate-rich WD repeat containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA replication, nucleosome assembly, nucleosome disassembly, ribosome biogenesis; MF: DNA replication origin binding, chromatin binding, histone binding; CC: chromosome, c... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Parn | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Parn in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Parn (poly(A)-specific ribonuclease (deadenylation nuclease))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA catabolic process, box H/ACA sno(s)RNA 3'-end processing, lncRNA processing, mRNA catabolic process, miRNA catabolic process, negative regulation of mac... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Bms1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Bms1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Bms1 (BMS1, ribosome biogenesis factor)
Type: protein-coding
Summary: Predicted to enable GTP binding activity; GTPase activity; and U3 snoRNA binding activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of SS... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Trim28 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Trim28 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Trim28 (tripartite motif-containing 28)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA methylation-dependent constitutive heterochromatin formation, DNA repair, chromatin organization, convergent extension involved in axis elongation, embryo implantation, embry... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpn1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpn1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpn1 (ribophorin I)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein glycosylation; CC: cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, membrane, oligosaccharyltran... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dbr1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dbr1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dbr1 (debranching RNA lariats 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA fragment catabolic process, RNA splicing, via transesterification reactions, mRNA processing, mRNA splicing, via spliceosome; MF: RNA lariat debranching enzyme activity, hydrolase a... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Opa1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Opa1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Opa1 (OPA1, mitochondrial dynamin like GTPase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: GTP metabolic process, apoptotic process, calcium import into the mitochondrion, cellular senescence, cristae formation, inner mitochondrial membrane organization, intrace... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rbbp4 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rbbp4 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rbbp4 (retinoblastoma binding protein 4, chromatin remodeling factor)
Type: protein-coding
Summary: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in DNA replication-dependent chromatin assembly; chromatin remodeling; and regulation... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Aldoa | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Aldoa in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Aldoa (aldolase A, fructose-bisphosphate)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ATP biosynthetic process, binding of sperm to zona pellucida, canonical glycolysis, fructose 1,6-bisphosphate metabolic process, fructose metabolic process, glycolytic process,... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dnaaf5 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dnaaf5 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dnaaf5 (dynein, axonemal assembly factor 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell projection organization, cilium movement, inner dynein arm assembly, outer dynein arm assembly; MF: dynein intermediate chain binding; CC: cytoplasm, cytosol, dynein axo... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dkc1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dkc1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dkc1 (dyskeratosis congenita 1, dyskerin)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA modification, RNA processing, box H/ACA sno(s)RNA 3'-end processing, box H/ACA sno(s)RNA metabolic process, enzyme-directed rRNA pseudouridine synthesis, mRNA pseudouridine... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Gatad2a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Gatad2a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Gatad2a (GATA zinc finger domain containing 2A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: anterior neuropore closure, blood vessel development, chromatin remodeling, embryonic body morphogenesis, in utero embryonic development, negative regulation of DNA-templ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Paf1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Paf1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Paf1 (Paf1, RNA polymerase II complex component)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Wnt signaling pathway, cellular response to lipopolysaccharide, endodermal cell fate commitment, mRNA 3'-end processing, negative regulation of myeloid cell differentiat... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Prmt5 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Prmt5 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Prmt5 (protein arginine N-methyltransferase 5)
Type: protein-coding
Summary: This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional e... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ddx19a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ddx19a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ddx19a (DEAD box helicase 19a)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: poly(A)+ mRNA export from nucleus, positive regulation of apoptotic process, response to zinc ion; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase a... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tuba1a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tuba1a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tuba1a (tubulin, alpha 1A)
Type: protein-coding
Summary: Enables GTP binding activity and protein heterodimerization activity. Involved in several processes, including learning or memory; microtubule cytoskeleton organization; and nervous system development. Located in cytoplasmic microtubule. Is ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Lars2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Lars2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Lars2 (leucyl-tRNA synthetase, mitochondrial)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: aminoacyl-tRNA metabolism involved in translational fidelity, leucyl-tRNA aminoacylation, mitochondrial translation, tRNA aminoacylation for protein translation, translatio... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pgd | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pgd in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pgd (phosphogluconate dehydrogenase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: D-gluconate metabolic process, NADP+ metabolic process, NADPH regeneration, pentose biosynthetic process, pentose-phosphate shunt, pentose-phosphate shunt, oxidative branch; MF: NAD... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Matr3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Matr3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Matr3 (matrin 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: activation of innate immune response, blastocyst formation, heart valve development, immune system process, innate immune response, post-transcriptional regulation of gene expression, ventricular septu... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eif3m | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eif3m in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eif3m (eukaryotic translation initiation factor 3, subunit M)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translational initiation, formation of cytoplasmic translation initiation complex, translation, translational initiation; MF: translation initia... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Hmbs | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Hmbs in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Hmbs (hydroxymethylbilane synthase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: heme A biosynthetic process, heme B biosynthetic process, heme biosynthetic process, liver development, porphyrin-containing compound biosynthetic process, porphyrin-containing compo... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Hsp90ab1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Hsp90ab1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Hsp90ab1 (heat shock protein 90 alpha (cytosolic), class B member 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to heat, cellular response to interleukin-4, chaperone-mediated protein complex assembly, negative regulation of apoptotic process,... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mars2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mars2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mars2 (methionine-tRNA synthetase 2 (mitochondrial))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: methionyl-tRNA aminoacylation, tRNA aminoacylation for protein translation, translation; MF: ATP binding, aminoacyl-tRNA ligase activity, ligase activity, methionine... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tmem70 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tmem70 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tmem70 (transmembrane protein 70)
Type: protein-coding
Summary: Predicted to enable mitochondrial proton-transporting ATP synthase complex binding activity. Involved in mitochondrial proton-transporting ATP synthase complex assembly. Located in mitochondrion. Is expressed in several structures, in... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl23a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl23a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl23a (ribosomal protein L23A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: RNA binding, TORC2 complex binding, large ribosomal subunit rRNA binding, protein binding... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cox17 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cox17 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cox17 (cytochrome c oxidase assembly protein 17, copper chaperone)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: heart development, mitochondrial cytochrome c oxidase assembly, positive regulation of cell population proliferation; MF: copper chaperone activity, co... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mbtps1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mbtps1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mbtps1 (membrane-bound transcription factor peptidase, site 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: NLS-bearing protein import into nucleus, cholesterol metabolic process, lipid metabolic process, lysosome organization, membrane protein intracellular doma... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Top1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Top1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Top1 (topoisomerase (DNA) I)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA replication, DNA topological change, animal organ regeneration, cellular response to luteinizing hormone stimulus, chromatin remodeling, chromosome segregation, circadian regulation of ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tefm | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tefm in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tefm (transcription elongation factor, mitochondrial)
Type: protein-coding
Summary: Predicted to enable DNA polymerase processivity factor activity and transcription elongation factor activity. Predicted to be involved in mitochondrial transcription; oxidative phosphorylation; and positive regulat... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Txnrd1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Txnrd1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Txnrd1 (thioredoxin reductase 1)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocys... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Esf1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Esf1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Esf1 (ESF1 nucleolar pre-rRNA processing protein homolog)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: rRNA processing; CC: nucleolus, nucleoplasm, nucleus
Pathways:
UniProt: Q3V1V3
Entrez ID: 66580 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Krr1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Krr1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Krr1 (KRR1, small subunit (SSU) processome component, homolog (yeast))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: rRNA processing, ribosomal small subunit biogenesis, ribosome biogenesis; MF: RNA binding, nucleic acid binding; CC: chromosome, intercellular brid... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eef2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eef2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eef2 (eukaryotic translation elongation factor 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to brain-derived neurotrophic factor stimulus, glial cell proliferation, hematopoietic progenitor cell differentiation, positive regulation of cytopla... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mios | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mios in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mios (meiosis regulator for oocyte development)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to amino acid starvation, cellular response to nutrient levels, central nervous system myelin formation, oligodendrocyte differentiation, oligodendrocyt... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Urm1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Urm1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Urm1 (ubiquitin related modifier 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein urmylation, tRNA processing, tRNA thio-modification, tRNA wobble uridine modification; MF: protein tag activity, sulfur carrier activity; CC: cytoplasm, cytosol, nucleus
... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Hmgcs1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Hmgcs1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Hmgcs1 (3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: acetyl-CoA metabolic process, cellular response to low-density lipoprotein particle stimulus, cholesterol biosynthetic process, cholesterol biosynthetic process... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cebpz | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cebpz in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cebpz (CCAAT/enhancer binding protein zeta)
Type: protein-coding
Summary: Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of CCAAT-binding activity factor complex. Predicted to be ac... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Lamtor1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Lamtor1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Lamtor1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: TORC1 signaling, autophagosome assembly, cellular response to amino acid stimulus, cellular response to nutrient levels, cholesterol homeostasis, cy... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Psmc6 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Psmc6 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Psmc6 (proteasome (prosome, macropain) 26S subunit, ATPase, 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ERAD pathway, positive regulation of RNA polymerase II transcription preinitiation complex assembly, positive regulation of inclusion body assembly, protea... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Vrk1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Vrk1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Vrk1 (vaccinia related kinase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Cajal body organization, DNA damage response, Golgi disassembly, cell division, chromatin remodeling, neuron projection development, positive regulation of protein localization to chrom... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nelfb | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nelfb in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nelfb (negative elongation factor complex member B)
Type: protein-coding
Summary: This gene encodes subunit B of a metazoan-specific, four-subunit protein complex that regulates promoter-proximal pausing of RNA polymerase II. RNA polymerase II pausing is thought to be important for coordination of... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rae1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rae1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rae1 (ribonucleic acid export 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA export from nucleus, cell division, nucleocytoplasmic transport, regulation of mitotic spindle organization, transcription-dependent tethering of RNA polymerase II gene DNA at nucle... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Polrmt | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Polrmt in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Polrmt (polymerase (RNA) mitochondrial (DNA directed))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA-templated transcription, mitochondrial transcription, transcription initiation at mitochondrial promoter; MF: 3'-5'-RNA exonuclease activity, 5'-3' RNA polymer... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Wdr33 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Wdr33 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Wdr33 (WD repeat domain 33)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mRNA 3'-end processing, mRNA processing; CC: collagen trimer, fibrillar center, mRNA cleavage and polyadenylation specificity factor complex, nucleoplasm, nucleus
Pathways: Gene exp... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nop16 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nop16 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nop16 (NOP16 nucleolar protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: nucleolus, nucleoplasm, nucleus
Pathways:
UniProt: Q9CPT5
Entrez ID: 28126 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Vps33a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Vps33a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Vps33a (VPS33A CORVET/HOPS core subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: autophagosome maturation, autophagy, endosome to lysosome transport, intracellular protein transport, lysosome localization, melanosome localization, pigmentation, platelet form... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mak16 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mak16 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mak16 (MAK16 homolog)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: maturation of 5.8S rRNA, maturation of LSU-rRNA; CC: nucleolus, nucleus, preribosome, large subunit precursor
Pathways:
UniProt: Q8BGS0
Entrez ID: 67920 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl31 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl31 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl31 (ribosomal protein L31)
Type: protein-coding
Summary: A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in early conceptus and embryo. Orthologous to h... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ybey | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ybey in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ybey (ybeY metallopeptidase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: RNA endonuclease activity, endonuclease activity, hydrolase activity, metal ion binding, metalloendopeptidase activity, nuclease activity; CC: mitochondrion, nucleus
Pathways:
... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pop5 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pop5 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pop5 (processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae))
Type: protein-coding
Summary: Enables ribonuclease P activity. Acts upstream of or within tRNA processing. Part of nucleolar ribonuclease P complex. Is expressed in Meckel's cartilage and skeleton. Orthologous to human POP... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Supt5 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Supt5 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Supt5 (suppressor of Ty 5, DSIF elongation factor subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA-templated transcription elongation, negative regulation of DNA-templated transcription, elongation, negative regulation of transcription by RNA polymerase ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cct3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cct3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cct3 (chaperonin containing TCP1 subunit 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: binding of sperm to zona pellucida, positive regulation of telomere maintenance via telomerase, protein folding, protein stabilization; MF: ATP binding, ATP hydrolysis activi... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ppa2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ppa2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ppa2 (pyrophosphatase (inorganic) 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: diphosphate metabolic process, phosphate-containing compound metabolic process, regulation of mitochondrial membrane potential; MF: hydrolase activity, inorganic diphosphate phospha... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Timm13 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Timm13 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Timm13 (translocase of inner mitochondrial membrane 13)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein insertion into mitochondrial inner membrane, protein transport; CC: fibrillar center, membrane, mitochondrial inner membrane, mitochondrial intermembrane ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Med22 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Med22 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Med22 (mediator complex subunit 22)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, positive regulation of transcription elongation by RNA polymerase II, positive regulation of transcription initiation by RNA polymer... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pnkp | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pnkp in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pnkp (polynucleotide kinase 3'- phosphatase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, double-strand break repair via nonhomologous end joining, positive regulation of double-strand break repair via nonhomologous end joining, p... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl14 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl14 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl14 (ribosomal protein L14)
Type: protein-coding
Summary: A structural constituent of ribosome. Predicted to be involved in rRNA processing and ribosomal large subunit biogenesis. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in several struc... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Top2a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Top2a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Top2a (topoisomerase (DNA) II alpha)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA metabolic process, DNA topological change, apoptotic chromosome condensation, chromatin organization, chromosome condensation, chromosome segregation, embry... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rac1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rac1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rac1 (Rac family small GTPase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, Rac protein signal transduction, Wnt signaling pathway, planar cell polarity pathway, actin cytoskeleton organization, actin filament organ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Alg8 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Alg8 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Alg8 (ALG8 alpha-1,3-glucosyltransferase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: dolichol-linked oligosaccharide biosynthetic process, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein glycosylation; MF: dolichyl pyropho... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mphosph6 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mphosph6 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mphosph6 (M phase phosphoprotein 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: maturation of 5.8S rRNA, rRNA processing; MF: RNA binding, molecular_function; CC: cytoplasm, cytosol, exosome (RNase complex), nuclear exosome (RNase complex), nucleolus, nucleoplas... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Imp3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Imp3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Imp3 (IMP3, U3 small nucleolar ribonucleoprotein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: rRNA processing, ribosomal small subunit biogenesis, ribosome biogenesis; MF: RNA binding, rRNA binding, snoRNA binding; CC: Mpp10 complex, cytosol, nucleolus, nucleopl... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Adat2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Adat2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Adat2 (adenosine deaminase, tRNA-specific 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: tRNA processing, tRNA wobble adenosine to inosine editing; MF: catalytic activity, hydrolase activity, metal ion binding, tRNA-specific adenosine deaminase activity, tRNA-sp... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tspyl1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tspyl1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tspyl1 (testis-specific protein, Y-encoded-like 1)
Type: protein-coding
Summary: Predicted to enable chromatin binding activity; enzyme binding activity; and histone binding activity. Predicted to be involved in nucleosome assembly. Predicted to be located in nucleolus and nucleoplasm. Predicted t... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Hjurp | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Hjurp in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Hjurp (Holliday junction recognition protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CENP-A containing chromatin assembly, chromosome segregation, regulation of protein-containing complex assembly; MF: DNA binding, histone binding, identical protein binding... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ptpn11 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ptpn11 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ptpn11 (protein tyrosine phosphatase, non-receptor type 11)
Type: protein-coding
Summary: Enables cell adhesion molecule binding activity; non-membrane spanning protein tyrosine phosphatase activity; and signaling receptor binding activity. Involved in several processes, including negative regulat... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Vhl | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Vhl in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Vhl (von Hippel-Lindau tumor suppressor)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: amyloid fibril formation, angiogenesis, blood vessel endothelial cell migration, camera-type eye morphogenesis, ciliary body morphogenesis, extracellular matrix organization, ey... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eif3j1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eif3j1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eif3j1 (eukaryotic translation initiation factor 3, subunit J1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translational initiation, formation of cytoplasmic translation initiation complex, translation, translational initiation; MF: identical protei... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dph6 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dph6 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dph6 (diphthamine biosynthesis 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein histidyl modification to diphthamide; MF: ATP binding, diphthine-ammonia ligase activity, ligase activity, nucleotide binding
Pathways: Gamma carboxylation, hypusinyla... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpp38 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpp38 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpp38 (ribonuclease P/MRP 38 subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: rRNA processing, tRNA 5'-leader removal, tRNA processing; MF: ribonuclease P RNA binding, ribonuclease P activity; CC: fibrillar center, multimeric ribonuclease P complex, nucleola... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ube4b | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ube4b in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ube4b (ubiquitination factor E4B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ERAD pathway, granzyme-mediated apoptotic signaling pathway, neuron projection development, proteasome-mediated ubiquitin-dependent protein catabolic process, protein autoubiquitinatio... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Polr1a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Polr1a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Polr1a (polymerase (RNA) I polypeptide A)
Type: protein-coding
Summary: Predicted to enable DNA/RNA hybrid binding activity; chromatin binding activity; and metal ion binding activity. Predicted to contribute to DNA-directed RNA polymerase activity. Predicted to be involved in negative regulation ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rnaseh2a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rnaseh2a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rnaseh2a (ribonuclease H2, large subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA replication, removal of RNA primer, RNA catabolic process, RNA metabolic process, mismatch repair; MF: RNA binding, RNA-DNA hybrid ribonuclease activity, endonuclease activ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps26 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps26 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps26 (ribosomal protein S26)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, negative regulation of RNA splicing, translation, translation at postsynapse, translation at presynapse; MF: mRNA binding, structural constituent of ribosome; CC: ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pde12 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pde12 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pde12 (phosphodiesterase 12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: antiviral innate immune response, cellular response to dsRNA, cellular response to interferon-alpha, cellular response to type II interferon, mRNA processing, mitochondrial mRNA catabolic p... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cenpo | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cenpo in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cenpo (centromere protein O)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, centromere complex assembly, chromosome segregation; CC: Mis6-Sim4 complex, chromosome, chromosome, centromeric region, inner kinetochore, kinetochore, nuclear body, nuc... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mrpl23 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mrpl23 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mrpl23 (mitochondrial ribosomal protein L23)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: cytosolic ribosome, fibrillar center, mitochondrial inner membrane, mitochondrial large r... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ppp2r3c | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ppp2r3c in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ppp2r3c (protein phosphatase 2, regulatory subunit B'', gamma)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: B cell homeostasis, T cell homeostasis, cortical cytoskeleton organization, microtubule cytoskeleton organization, positive regulation of B cell differenti... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpsa | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpsa in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpsa (ribosomal protein SA)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell adhesion, cytoplasmic translation, ribosomal small subunit assembly, translation; MF: DNA binding, laminin binding, laminin receptor activity, protein binding, ribosome binding, structu... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dph1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dph1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dph1 (diphthamide biosynthesis 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: fibroblast proliferation, protein histidyl modification to diphthamide; MF: 2-(3-amino-3-carboxypropyl)histidine synthase activity, 4 iron, 4 sulfur cluster binding, iron-sulfur cluste... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tcea1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tcea1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tcea1 (transcription elongation factor A (SII) 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA-templated transcription, erythrocyte differentiation, positive regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II,... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Armc7 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Armc7 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Armc7 (armadillo repeat containing 7)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, biological_process, mRNA processing
Pathways:
UniProt: Q3UJZ3
Entrez ID: 276905 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Supt4a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Supt4a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Supt4a (SPT4A, DSIF elongation factor subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of DNA-templated transcription, elongation, negative regulation of transcription by RNA polymerase II, negative regulation of transcription elongation ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Coa6 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Coa6 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Coa6 (cytochrome c oxidase assembly factor 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial cytochrome c oxidase assembly, respiratory chain complex IV assembly; MF: copper ion binding; CC: mitochondrial intermembrane space, mitochondrion, nucleoplas... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Gtf2b | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Gtf2b in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Gtf2b (general transcription factor IIB)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA-templated transcription initiation, RNA polymerase II core complex assembly, RNA polymerase II preinitiation complex assembly, chromatin remodeling, chromosome organization,... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dnajc9 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dnajc9 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dnajc9 (DnaJ heat shock protein family (Hsp40) member C9)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: nucleosome assembly; MF: heat shock protein binding, histone binding, protein-folding chaperone binding; CC: cytoplasm, cytosol, extracellular space, membrane, ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Wdr48 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Wdr48 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Wdr48 (WD repeat domain 48)
Type: protein-coding
Summary: Predicted to enable DNA binding activity; deubiquitinase activator activity; and ubiquitin binding activity. Acts upstream of or within several processes, including double-strand break repair via homologous recombination; regulation of prot... |
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