screen_file string | organism string | perturbation string | gene string | cell string | phenotype string | hit int64 | benchmark_type string | prompt string | gene_context string |
|---|---|---|---|---|---|---|---|---|---|
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ctcf | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ctcf in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ctcf (CCCTC-binding factor)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA methylation-dependent constitutive heterochromatin formation, cardiac muscle cell development, cardiac muscle cell differentiation, chromatin looping, chromatin organization, chromosome ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Foxk2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Foxk2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Foxk2 (forkhead box K2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: canonical glycolysis, intracellular glucose homeostasis, negative regulation of DNA-templated transcription, negative regulation of autophagy, negative regulation of transcription by RNA polymer... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Taf1c | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Taf1c in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Taf1c (TATA-box binding protein associated factor, RNA polymerase I, C)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA polymerase I preinitiation complex assembly, transcription by RNA polymerase I; MF: DNA binding, RNA polymerase I core promoter sequence-speci... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Scd2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Scd2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Scd2 (stearoyl-Coenzyme A desaturase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: fatty acid biosynthetic process, fatty acid metabolic process, lipid metabolic process, monounsaturated fatty acid biosynthetic process, response to fatty acid, unsaturated fatty... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tecr | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tecr in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tecr (trans-2,3-enoyl-CoA reductase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: fatty acid biosynthetic process, fatty acid elongation, fatty acid metabolic process, lipid metabolic process, sphingolipid metabolic process, steroid biosynthetic process, very lon... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pfn1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pfn1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pfn1 (profilin 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: actin cytoskeleton organization, modification of postsynaptic actin cytoskeleton, modulation of chemical synaptic transmission, negative regulation of actin filament bundle assembly, negative regulati... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Alg11 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Alg11 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Alg11 (ALG11 alpha-1,2-mannosyltransferase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: dolichol-linked oligosaccharide biosynthetic process, protein N-linked glycosylation; MF: GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity, glycosyltrans... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cenpu | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cenpu in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cenpu (centromere protein U)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chordate embryonic development, chromosome segregation; CC: centriolar satellite, chromosome, chromosome, centromeric region, cytoplasm, inner kinetochore, kinetochore, nucleoplasm, nucleus... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ermp1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ermp1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ermp1 (endoplasmic reticulum metallopeptidase 1)
Type: protein-coding
Summary: Predicted to enable metal ion binding activity and metalloexopeptidase activity. Predicted to be involved in cellular response to oxidative stress; ovarian follicle development; and proteolysis. Predicted to act upstrea... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ncbp1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ncbp1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ncbp1 (nuclear cap binding protein subunit 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: 7-methylguanosine mRNA capping, RNA catabolic process, RNA metabolic process, RNA splicing, alternative mRNA splicing, via spliceosome, cap-dependent translational initiati... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Baz1b | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Baz1b in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Baz1b (bromodomain adjacent to zinc finger domain, 1B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, chromatin organization, chromatin remodeling, negative regulation of mitotic chromosome condensation, positive regulation of transcription by ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ppil2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ppil2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ppil2 (peptidylprolyl isomerase (cyclophilin)-like 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, mRNA processing, protein folding, protein localization to plasma membrane, protein polyubiquitination, protein ubiquitination; MF: peptidyl-prolyl cis... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rnaseh1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rnaseh1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rnaseh1 (ribonuclease H1)
Type: protein-coding
Summary: This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and is necessary for DNA replication and repair. This enzyme is present in both mitochondria and nuclei, which are resulted from translation of a single m... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ankrd52 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ankrd52 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ankrd52 (ankyrin repeat domain 52)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q8BTI7
Entrez ID: 237615 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Polr3h | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Polr3h in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Polr3h (polymerase (RNA) III (DNA directed) polypeptide H)
Type: protein-coding
Summary: Predicted to enable DNA-directed RNA polymerase activity. Predicted to be involved in transcription initiation at RNA polymerase III promoter. Predicted to be located in centrosome and nucleoplasm. Predicted t... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Atp1a1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Atp1a1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Atp1a1 (ATPase, Na+/K+ transporting, alpha 1 polypeptide)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to mechanical stimulus, cellular response to steroid hormone stimulus, establishment or maintenance of transmembrane electrochemical gradient,... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ddx49 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ddx49 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ddx49 (DEAD box helicase 49)
Type: protein-coding
Summary: Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be involved in positive regulation of cell growth; rRNA processing; and regulation of rRNA stability. P... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ccnt1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ccnt1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ccnt1 (cyclin T1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell division, host-mediated activation of viral transcription, positive regulation of DNA-templated transcription, elongation, positive regulation of transcription by RNA polymerase II, positive regu... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Hnrnpab | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Hnrnpab in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Hnrnpab (heterogeneous nuclear ribonucleoprotein A/B)
Type: protein-coding
Summary: This gene encodes a protein with consensus RNA binding domains present in a number of other RNA binding proteins and a glycine-rich C-terminus. This gene overlaps in a tail-to-tail orientation the gene encoding ala... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps27a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps27a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps27a (ribosomal protein S27A)
Type: protein-coding
Summary: Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in modification-dependent protein catabolic process; protein ubiquiti... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Syncrip | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Syncrip in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Syncrip (synaptotagmin binding, cytoplasmic RNA interacting protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CRD-mediated mRNA stabilization, RNA splicing, cellular response to type II interferon, chromosomal 5-methylcytosine DNA demethylation pathway, mRNA ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tufm | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tufm in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tufm (Tu translation elongation factor, mitochondrial)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translational elongation, translation, translational elongation; MF: GTP binding, GTPase activity, hydrolase activity, magnesium ion binding, metal i... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Gnl2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Gnl2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Gnl2 (guanine nucleotide binding protein nucleolar 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: GTP binding, nucleotide binding; CC: nucleolus, nucleus
Pathways: Ribosome biogenesis in eukaryotes - Mus musculus (mouse)
UniProt: Q99LH1
... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Trrap | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Trrap in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Trrap (transformation/transcription domain-associated protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin organization, positive regulation of DNA-templated transcription, positive regulation of biosynthetic process, positive regulation of double-stra... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps19bp1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps19bp1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps19bp1 (ribosomal protein S19 binding protein 1)
Type: protein-coding
Summary: Predicted to enable enzyme binding activity. Predicted to be involved in ribosomal small subunit biogenesis. Located in nucleolus and nucleoplasm. Is expressed in brain; male reproductive gland or organ; and metanephr... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ddx18 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ddx18 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ddx18 (DEAD box helicase 18)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to estradiol stimulus, maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cuta | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cuta in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cuta (cutA divalent cation tolerance homolog)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: intracellular protein localization, response to metal ion; MF: copper ion binding, enzyme binding; CC: membrane, mitochondrion
Pathways:
UniProt: Q9CQ89
... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Hsd17b12 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Hsd17b12 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: estrogen biosynthetic process, extracellular matrix organization, fatty acid biosynthetic process, fatty acid elongation, saturated fatty acid, lipid metabolic proce... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Txn2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Txn2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Txn2 (thioredoxin 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: peptide-methionine (R)-S-oxide reductase activity, peptide-methionine (S)-S-oxide reductase activity, protein-containing complex binding, protein-disulfide reductase activity; CC: dendrite, mitocho... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dynlrb1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dynlrb1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dynlrb1 (dynein light chain roadblock-type 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: microtubule-based movement, visual behavior; MF: dynein intermediate chain binding, identical protein binding, protein binding; CC: centrosome, cytoplasm, cytoplasmic dynei... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ciapin1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ciapin1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ciapin1 (cytokine induced apoptosis inhibitor 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, hemopoiesis, iron-sulfur cluster assembly, negative regulation of apoptotic process; MF: 2 iron, 2 sulfur cluster binding, 4 iron, 4 sulfur cluster bi... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Sap18 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Sap18 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Sap18 (Sin3-associated polypeptide 18)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, mRNA processing, negative regulation of DNA-templated transcription, negative regulation of mRNA splicing, via spliceosome, positive regulation of apoptotic process,... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nrbp2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nrbp2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nrbp2 (nuclear receptor binding protein 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: intracellular signal transduction, negative regulation of macroautophagy, negative regulation of neuron apoptotic process, nervous system development, neuron differentiation; ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nsd1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nsd1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nsd1 (nuclear receptor-binding SET-domain protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin organization, chromatin remodeling, gastrulation with mouth forming second, methylation, negative regulation of DNA-templated transcription, negative regul... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Map2k7 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Map2k7 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Map2k7 (mitogen-activated protein kinase kinase 7)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: JNK cascade, apoptotic process, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to osmotic stress, positive regulation o... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dennd6a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dennd6a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dennd6a (DENN domain containing 6A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of cell-cell adhesion mediated by cadherin; MF: guanyl-nucleotide exchange factor activity; CC: cytoplasm, endosome, recycling endosome
Pathways: Membran... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pet117 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pet117 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pet117 (PET117 homolog)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: mitochondrion
Pathways:
UniProt: P0DJF2
Entrez ID: 100048644 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Sco1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Sco1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Sco1 (SCO1 cytochrome c oxidase assembly protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: copper ion homeostasis, cyclooxygenase pathway, gene expression, homeostasis of number of cells, immune response, intracellular copper ion homeostasis, intracellular ir... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mrps28 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mrps28 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mrps28 (mitochondrial ribosomal protein S28)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation; CC: mitochondrial inner membrane, mitochondrial small ribosomal subunit, mitochondrion, ribonucleoprotein complex, ribosome
Pathways: Met... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Trit1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Trit1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Trit1 (tRNA isopentenyltransferase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial tRNA modification, tRNA modification, tRNA processing; MF: ATP binding, metal ion binding, nucleotide binding, tRNA dimethylallyltransferase activity, transferase act... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dlst | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dlst in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dlst (dihydrolipoamide S-succinyltransferase)
Type: protein-coding
Summary: Predicted to enable dihydrolipoyllysine-residue succinyltransferase activity; heat shock protein binding activity; and protein-folding chaperone binding activity. Predicted to be involved in 2-oxoglutarate metabolic proces... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Sod2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Sod2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Sod2 (superoxide dismutase 2, mitochondrial)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure, apoptotic mitochondrial changes, cellular response to ethanol, cellular respo... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tra2b | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tra2b in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tra2b (transformer 2 beta)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, cellular response to glucose stimulus, cerebral cortex regionalization, embryonic brain development, mRNA processing, mRNA splicing, via spliceosome, positive regulation of mRNA... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dnajc11 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dnajc11 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dnajc11 (DnaJ heat shock protein family (Hsp40) member C11)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cristae formation; CC: MICOS complex, SAM complex, membrane, mitochondrial inner membrane, mitochondrial outer membrane, mitochondrion, nuclear speck, nucleop... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl7 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl7 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl7 (ribosomal protein L7)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), rRNA processing, ribosomal large subunit biogenesis, translation, translati... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Gm4836 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Gm4836 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Gm4836 (predicted gene 4836)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: nucleus
Pathways:
UniProt: Q62478
Entrez ID: 22526 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Leo1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Leo1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Leo1 (Leo1, Paf1/RNA polymerase II complex component)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Wnt signaling pathway, endodermal cell fate commitment, mRNA 3'-end processing, negative regulation of myeloid cell differentiation, positive regulation of transcri... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Zfp65 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Zfp65 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Zfp65 (zinc finger protein 65)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps14 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps14 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps14 (ribosomal protein S14)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, erythrocyte differentiation, maturation of SSU-rRNA, negative regulation of transcription by RNA polymerase II, ribosomal small subunit assembly, ribosomal small s... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Fam118a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Fam118a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Fam118a (family with sequence similarity 118, member A)
Type: protein-coding
Summary: Predicted to enable identical protein binding activity. Predicted to be located in membrane. Is expressed in cerebral cortex and cerebral cortex marginal layer. Orthologous to human FAM118A (family with sequence ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ap2s1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ap2s1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ap2s1 (adaptor-related protein complex 2, sigma 1 subunit)
Type: protein-coding
Summary: Predicted to enable clathrin adaptor activity. Predicted to be involved in postsynaptic neurotransmitter receptor internalization and synaptic vesicle endocytosis. Part of AP-2 adaptor complex. Is active in sy... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Phb2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Phb2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Phb2 (prohibitin 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: B cell activation, RIG-I signaling pathway, antiviral innate immune response, cell migration, mammary gland alveolus development, mammary gland branching involved in thelarche, mitochondrion organiz... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Gatb | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Gatb in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Gatb (glutamyl-tRNA amidotransferase subunit B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: glutaminyl-tRNAGln biosynthesis via transamidation, mitochondrial translation, translation; MF: ATP binding, carbon-nitrogen ligase activity, with glutamine as amido-N-do... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Uqcc2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Uqcc2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Uqcc2 (ubiquinol-cytochrome c reductase complex assembly factor 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial respiratory chain complex III assembly, positive regulation of mitochondrial translation, regulation of insulin secretion, regulation of ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ndufs2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ndufs2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ndufs2 (NADH:ubiquinone oxidoreductase core subunit S2)
Type: protein-coding
Summary: Enables NADH dehydrogenase (ubiquinone) activity and oxygen sensor activity. Involved in several processes, including cellular response to oxygen levels; gliogenesis; and mitochondrial respiratory chain complex I... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Bend3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Bend3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Bend3 (BEN domain containing 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA methylation-dependent constitutive heterochromatin formation, chromatin organization, negative regulation of transcription by RNA polymerase II, positive regulation of ATP metabolic ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ranbp2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ranbp2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ranbp2 (RAN binding protein 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: NLS-bearing protein import into nucleus, centrosome localization, cytoplasmic pattern recognition receptor signaling pathway, intracellular glucose homeostasis, mRNA transport, negative r... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Thap1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Thap1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Thap1 (THAP domain containing, apoptosis associated protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA-templated transcription, endothelial cell proliferation, negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcr... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ncbp2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ncbp2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ncbp2 (nuclear cap binding protein subunit 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, alternative mRNA splicing, via spliceosome, cap-dependent translational initiation, histone mRNA metabolic process, mRNA 3'-end processing, mRNA cis splicing,... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Gins3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Gins3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Gins3 (GINS complex subunit 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA replication, cellular senescence, multicellular organism growth; CC: CMG complex, GINS complex, chromosome, nucleoplasm, nucleus
Pathways: Cell Cycle, Cell Cycle, Mitotic, DN... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tmem208 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tmem208 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tmem208 (transmembrane protein 208)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: autophagy, vacuolar protein processing; CC: endoplasmic reticulum, endoplasmic reticulum membrane, intracellular membrane-bounded organelle, membrane, vacuole
Pathways:
... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Sox10 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Sox10 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Sox10 (SRY (sex determining region Y)-box 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell differentiation, cell maturation, cellular response to progesterone stimulus, cellular response to xenobiotic stimulus, central nervous system myelination, development... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mrps11 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mrps11 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mrps11 (mitochondrial ribosomal protein S11)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial small ribosomal subunit, mitochondrion, ribon... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Zbtb17 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Zbtb17 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Zbtb17 (zinc finger and BTB domain containing 17)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G1 to G0 transition, ectoderm development, gastrulation with mouth forming second, negative regulation of cell population proliferation, positive regulation of DNA-temp... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Bop1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Bop1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Bop1 (block of proliferation 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell population proliferation, cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of 5.8S rRNA, maturation of 5.8... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Kras | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Kras in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Kras (Kirsten rat sarcoma viral oncogene homolog)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Ras protein signal transduction, actin cytoskeleton organization, cardiac muscle cell proliferation, cytokine-mediated signaling pathway, epithelial tube branching invo... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nxf1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nxf1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nxf1 (nuclear RNA export factor 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA export from nucleus, mRNA export from nucleus, mRNA transport, poly(A)+ mRNA export from nucleus, protein transport; MF: RNA binding, mRNA binding, nucleic acid binding, protein b... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rnaseh2c | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rnaseh2c in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rnaseh2c (ribonuclease H2, subunit C)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA catabolic process, mismatch repair; CC: nucleus, ribonuclease H2 complex
Pathways: DNA replication - Mus musculus (mouse)
UniProt: Q9CQ18
Entrez ID: 6... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Hspa5 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Hspa5 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Hspa5 (heat shock protein 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ER overload response, ERAD pathway, IRE1-mediated unfolded protein response, PERK-mediated unfolded protein response, cellular response to glucose starvation, cellular response to interleuk... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Prmt1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Prmt1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Prmt1 (protein arginine N-methyltransferase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: BMP signaling pathway, DNA damage response, RNA splicing, TORC1 signaling, cardiac muscle tissue development, cellular response to amino acid starvation, cellular response... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eif4e | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eif4e in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eif4e (eukaryotic translation initiation factor 4E)
Type: protein-coding
Summary: This gene encodes a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dnm1l | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dnm1l in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dnm1l (dynamin 1-like)
Type: protein-coding
Summary: This gene encodes a member of the dynamin family. The encoded protein is localized to the cytoplasm and mitochondrial membrane, is involved in mitochondrial and peroxisomal division, and is essential for mitochondrial fission. Alternative splici... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dusp12 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dusp12 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dusp12 (dual specificity phosphatase 12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: hydrolase activity, kinase binding, metal ion binding, phosphatase activity, phosphoprotein phosphatase activity, protein serine/threonine phosphatase activity, protein tyrosine... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rev1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rev1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rev1 (REV1, DNA directed polymerase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA biosynthetic process, DNA damage response, DNA metabolic process, DNA repair, error-free translesion synthesis, error-prone translesion synthesis, response to UV, somatic hyperm... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Vps16 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Vps16 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Vps16 (VSP16 CORVET/HOPS core subunit)
Type: protein-coding
Summary: Enables actin binding activity. Acts upstream of or within symbiont entry into host cell. Located in actin filament; clathrin-coated vesicle; and early endosome membrane. Part of AP-3 adaptor complex and CORVET complex. Used to s... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Srsf11 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Srsf11 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Srsf11 (serine and arginine-rich splicing factor 11)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (R... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Fbl | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Fbl in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Fbl (fibrillarin)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: box C/D sno(s)RNA 3'-end processing, chromatin remodeling, methylation, rRNA methylation, rRNA processing, ribosomal small subunit biogenesis, sno(s)RNA metabolic process, snoRNA localization; MF: ATP... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Stoml2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Stoml2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Stoml2 (stomatin (Epb7.2)-like 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CD4-positive, alpha-beta T cell activation, T cell receptor signaling pathway, intracellular calcium ion homeostasis, lipid localization, mitochondrial protein processing, mitochondrio... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mrpl16 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mrpl16 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mrpl16 (mitochondrial ribosomal protein L16)
Type: protein-coding
Summary: Predicted to enable rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to act upstream of or within translation. Located in mitochon... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Atp6v0c | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Atp6v0c in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Atp6v0c (ATPase, H+ transporting, lysosomal V0 subunit C)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: lysosomal lumen acidification, monoatomic ion transport, negative regulation of autophagic cell death, positive regulation of ERK1 and ERK2 cascade, positive re... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mrpl33 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mrpl33 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mrpl33 (mitochondrial ribosomal protein L33)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, translation; CC: cytosol, mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, ribonucleoprotein complex, ribosome
... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mad2l1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mad2l1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mad2l1 (MAD2 mitotic arrest deficient-like 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell division, establishment of centrosome localization, establishment of mitotic spindle orientation, mitotic sister chromatid segregation, mitotic spindle assembly checkp... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Acat2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Acat2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Acat2 (acetyl-Coenzyme A acetyltransferase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cholesterol biosynthetic process via desmosterol, cholesterol biosynthetic process via lathosterol, fatty acid metabolic process, isopentenyl diphosphate biosynthetic proce... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Gm9758 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Gm9758 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Gm9758 (predicted gene 9758)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q80ZT2
Entrez ID: 381714 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl30 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl30 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl30 (ribosomal protein L30)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: antimicrobial humoral immune response mediated by antimicrobial peptide, cytoplasmic translation, defense response to Gram-negative bacterium, killing of cells of another organism; MF: RNA... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rbm41 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rbm41 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rbm41 (RNA binding motif protein 41)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: RNA binding, U12 snRNA binding, nucleic acid binding, pre-mRNA intronic binding
Pathways:
UniProt: Q8JZV4
Entrez ID: 237073 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cstf2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cstf2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cstf2 (cleavage stimulation factor, 3' pre-RNA subunit 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to nerve growth factor stimulus, mRNA 3'-end processing, mRNA processing; MF: RNA binding, mRNA binding, nucleic acid binding; CC: cleavage bo... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Vmn2r36 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Vmn2r36 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Vmn2r36 (vomeronasal 2, receptor 36)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane
Pathways:
UniProt: K7N74... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Fh1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Fh1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Fh1 (fumarate hydratase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, arginine metabolic process, fumarate metabolic process, homeostasis of number of cells within a tissue, malate metabolic process, positive regulation of cold-... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Smc6 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Smc6 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Smc6 (structural maintenance of chromosomes 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, cellular senescence, double-strand break repair, double-strand break repair via homologous recombination, host-mediated... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ndufb8 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ndufb8 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ndufb8 (NADH:ubiquinone oxidoreductase subunit B8)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: aerobic respiration, mitochondrial electron transport, NADH to ubiquinone, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner me... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Shf | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Shf in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Shf (Src homology 2 domain containing F)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, signal transduction
Pathways:
UniProt: Q8CG80
Entrez ID: 435684 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Kat8 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Kat8 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Kat8 (K(lysine) acetyltransferase 8)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin organization, dosage compensation by inactivation of X chromosome, epigenetic regulation of gene expression, epithelial to mesenchymal transition, germ cell development, h... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Polr3f | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Polr3f in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Polr3f (polymerase (RNA) III (DNA directed) polypeptide F)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: defense response to virus, immune system process, innate immune response, positive regulation of innate immune response, positive regulation of interferon-beta... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ppan | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ppan in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ppan (peter pan homolog)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), rRNA processing, regulation of cell growth by extracellular stimulus; MF: rRNA binding; CC: nucleolus, ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Alyref | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Alyref in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Alyref (Aly/REF export factor)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA export from nucleus, RNA folding, RNA splicing, mRNA export from nucleus, mRNA processing, mRNA transport; MF: C5-methylcytidine-containing RNA reader activity, RNA binding, RNA foldi... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nup62 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nup62 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nup62 (nucleoporin 62)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA export from nucleus, cell migration, cell surface receptor signaling pathway, cellular senescence, centriole assembly, centrosome cycle, mRNA transport, mitotic centrosome separation, mitotic... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mrpl52 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mrpl52 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mrpl52 (mitochondrial ribosomal protein L52)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, nucle... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Wdr82 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Wdr82 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Wdr82 (WD repeat domain containing 82)
Type: protein-coding
Summary: Enables chromatin binding activity and lncRNA binding activity. Involved in RNA catabolic process and negative regulation of DNA-templated transcription. Acts upstream of or within gene expression. Located in nucleus. Is expresse... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps12 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps12 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps12 (ribosomal protein S12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, maintenance of translational fidelity, positive regulation of canonical Wnt signaling pathway, ribosomal small subunit biogenesis, translation, translation at post... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.