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Does Knockout of Pcmtd1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Pcmtd1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pcmtd1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein ubiquitination; MF: S-adenosylmethionine-dependent methyltransferase activity, protein-L-isoaspartate (D-aspartate) O-methyl...
Does Knockout of Zfp940 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Zfp940
cell proliferation
Colonic Cancer Cell Line
Gene: Zfp940 (zinc finger protein 940) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II...
Does Knockout of Hcn3 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Hcn3
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Hcn3 (hyperpolarization-activated, cyclic nucleotide-gated K+ 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to cAMP, monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion transmembrane transport, potassium ion transpo...
Does Knockout of Gm9869 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,279
Knockout
Gm9869
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Gm9869 (predicted gene 9869) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Usp20 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Usp20
cell proliferation
Colonic Cancer Cell Line
Gene: Usp20 (ubiquitin specific peptidase 20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antiviral innate immune response, canonical NF-kappaB signal transduction, endocytosis, negative regulation of canonical NF-kappaB signal transduction, nervous system development...
Does Knockout of Cldn12 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Cldn12
protein/peptide accumulation
Embryonic Cell Line
Gene: Cldn12 (claudin 12) Type: protein-coding Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the para...
Does Knockout of Wdsub1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Wdsub1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Wdsub1 (WD repeat, SAM and U-box domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, protein ubiquitination; MF: molecular_function, ubiquitin-protein transferase activity Pathways: UniProt: Q9D0I6 Entr...
Does Knockout of Adarb2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Adarb2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Adarb2 (adenosine deaminase, RNA-specific, B2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 3'-UTR-mediated mRNA stabilization, RNA processing, adenosine to inosine editing, mRNA processing; MF: RNA binding, adenosine deaminase activity, double-stranded RNA adeno...
Does Knockout of Prrg3 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Prrg3
response to chemicals
Pancreatic Cancer Cell Line
Gene: Prrg3 (proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)) Type: protein-coding Summary: This gene encodes proline-rich gamma-carboxyglutamic acid protein 3, a member of vitamin K-dependent membrane proteins containing gamma-carboxyglutamic acid residues. The encoded precursor protein con...
Does Knockout of Larp1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Larp1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Larp1 (La ribonucleoprotein 1, translational regulator) Type: protein-coding Summary: No summary available. Gene Ontology: BP: TOR signaling, TORC1 signaling, cell population proliferation, cellular response to rapamycin, mRNA stabilization, negative regulation of translation, negative re...
Does Knockout of Det1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Det1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Det1 (DET1 partner of COP1 E3 ubiquitin ligase) Type: protein-coding Summary: Predicted to enable ubiquitin protein ligase binding activity and ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic pro...
Does Knockout of Tmem268 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,398
Knockout
Tmem268
protein/peptide accumulation
Microglial Cell Line
Gene: Tmem268 (transmembrane protein 268) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane, plasma membrane Pathways: UniProt: Q8R239 Entrez ID: 230279
Does Knockout of Tead4 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Tead4
protein/peptide accumulation
Mouse cell
Gene: Tead4 (TEA domain family member 4) Type: protein-coding Summary: This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT ...
Does Knockout of Tmem132d in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Tmem132d
cell proliferation
Melanoma Cell Line
Gene: Tmem132d (transmembrane protein 132D) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q76HP3 Entrez ID: 243274
Does Knockout of Dgat2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Dgat2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Dgat2 (diacylglycerol O-acyltransferase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to oleic acid, cholesterol homeostasis, diacylglycerol biosynthetic process, diacylglycerol metabolic process, fat pad development, fatty acid homeostasis, g...
Does Knockout of Zfyve28 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Zfyve28
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfyve28 (zinc finger, FYVE domain containing 28) Type: protein-coding Summary: Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in negative regulation of epidermal growth factor-activated receptor activity. Predicted to be located in cytosol. Predicte...
Does Knockout of Guk1 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Guk1
protein/peptide distribution
Microglial Cell Line
Gene: Guk1 (guanylate kinase 1) Type: protein-coding Summary: Enables ATP binding activity and guanylate kinase activity. Involved in purine nucleotide metabolic process. Located in cytosol and photoreceptor inner segment. Is expressed in several structures, including alimentary system; genitourinary sy...
Does Knockout of Wdr54 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Wdr54
cell viability
Immortal mouse chromaffin cells
Gene: Wdr54 (WD repeat domain 54) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fusion of sperm to egg plasma membrane involved in single fertilization, negative regulation of receptor internalization, regulation of MAPK cascade, regulation of epidermal growth factor re...
Does Knockout of Gm5108 in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Gm5108
cell cycle progression
breast epithelium
Gene: Gm5108 (predicted gene 5108) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 330097
Does Knockout of Cgn in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Cgn
cell viability
Immortal mouse chromaffin cells
Gene: Cgn (cingulin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bicellular tight junction assembly, epithelial cell morphogenesis, microtubule cytoskeleton organization; MF: actin binding, microtubule binding, protein binding; CC: anchoring junction, apical junction ...
Does Knockout of Hspa1l in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Hspa1l
cell proliferation
Melanoma Cell Line
Gene: Hspa1l (heat shock protein 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: binding of sperm to zona pellucida, cell differentiation, positive regulation of protein targeting to mitochondrion, protein folding, protein refolding, spermatogenesis; MF: ATP bindi...
Does Knockout of Fbxo25 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Fbxo25
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Fbxo25 (F-box protein 25) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein ubiquitination; MF: actin binding, protein binding; CC: SCF ubiquitin ligase complex, cytoplasm, nucleus Pathways: FoxO signaling pathway - Mus musculus (mouse) UniPr...
Does Knockout of Brwd3 in Melanoma Cell Line causally result in tumorigenicity?
0
2,186
Knockout
Brwd3
tumorigenicity
Melanoma Cell Line
Gene: Brwd3 (bromodomain and WD repeat domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoskeleton organization, regulation of cell shape, regulation of transcription by RNA polymerase II Pathways: UniProt: A2AHJ4 Entrez ID...
Does Knockout of Slc7a5 in Cytotoxic T-lymphocyte (CD8+ T cells) causally result in cell proliferation?
1
2,412
Knockout
Slc7a5
cell proliferation
Cytotoxic T-lymphocyte (CD8+ T cells)
Gene: Slc7a5 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-amino acid transport, L-histidine transport, L-leucine import across plasma membrane, L-leucine transport, L-tryptophan transmem...
Does Knockout of Sec11c in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Sec11c
cell proliferation
Regulatory T cell
Gene: Sec11c (SEC11 homolog C, signal peptidase complex subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteolysis, signal peptide processing; MF: hydrolase activity, peptidase activity, serine-type endopeptidase activity; CC: endoplasmic reticulum, endoplasmic ...
Does Knockout of Sephs2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
1,565
Knockout
Sephs2
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Sephs2 (selenophosphate synthetase 2) Type: protein-coding Summary: This gene encodes an enzyme that catalyzes the production of monoselenophosphate (MSP) from selenide and ATP. MSP is the selenium donor required for synthesis of selenocysteine (Sec), which is co-translationally incorporated into ...
Does Knockout of Eif3i in macrophage causally result in phagocytosis?
0
1,889
Knockout
Eif3i
phagocytosis
macrophage
Gene: Eif3i (eukaryotic translation initiation factor 3, subunit I) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translational initiation, formation of cytoplasmic translation initiation complex, translation, translational initiation; MF: RNA binding, prote...
Does Knockout of Psg29 in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Psg29
response to virus
Neuroblastoma Cell Line
Gene: Psg29 (pregnancy-specific beta-1-glycoprotein 29) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of immune system process, signal transduction; CC: cell surface, plasma membrane Pathways: Cell surface interactions at the vascular wall, Hemostasi...
Does Knockout of Lama3 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Lama3
cell proliferation
Melanoma Cell Line
Gene: Lama3 (laminin, alpha 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ morphogenesis, axon guidance, cell adhesion, cell-cell adhesion, endodermal cell differentiation, hemidesmosome assembly, regulation of cell adhesion, regulation of cell migration,...
Does Knockout of Gnat3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Gnat3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Gnat3 (G protein subunit alpha transducin 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, detection of light stimulus involved in visual perce...
Does Knockout of Zeb2 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Zeb2
protein/peptide distribution
Microglial Cell Line
Gene: Zeb2 (zinc finger E-box binding homeobox 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: astrocyte activation, cell proliferation in forebrain, central nervous system development, collateral sprouting, corpus callosum morphogenesis, corticospinal tract morphogene...
Does Knockout of Plekhf2 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Plekhf2
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Plekhf2 (pleckstrin homology domain containing, family F (with FYVE domain) member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endosome organization, endosome to lysosome transport, protein transport; MF: metal ion binding, phosphatidylinositol binding, zinc ...
Does Knockout of Zar1l in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,263
Knockout
Zar1l
cell proliferation
Colonic Cancer Cell Line
Gene: Zar1l (zygote arrest 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, negative regulation of translation, oocyte maturation, oogenesis, translation; MF: RNA binding, mRNA 3'-UTR binding, mRNA binding, metal ion binding, protein binding, ...
Does Knockout of Dynlrb1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,259
Knockout
Dynlrb1
cell proliferation
Mouse kidney carcinoma cell
Gene: Dynlrb1 (dynein light chain roadblock-type 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule-based movement, visual behavior; MF: dynein intermediate chain binding, identical protein binding, protein binding; CC: centrosome, cytoplasm, cytoplasmic dynei...
Does Knockout of Pogk in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,308
Knockout
Pogk
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Pogk (pogo transposable element with KRAB domain) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, regulation of DNA-templated transcription; MF: DNA binding, molecular_function, nucleic acid binding; CC: nucleoplasm, nucleus Pathways: ...
Does Knockout of Mmel1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Mmel1
protein/peptide accumulation
Embryonic Cell Line
Gene: Mmel1 (membrane metallo-endopeptidase-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein processing, proteolysis; MF: endopeptidase activity, hydrolase activity, metal ion binding, metalloendopeptidase activity, metallopeptidase activity, peptidase acti...
Does Knockout of Cndp2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Cndp2
protein/peptide accumulation
Embryonic Cell Line
Gene: Cndp2 (CNDP dipeptidase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteolysis; MF: carboxypeptidase activity, dipeptidase activity, hydrolase activity, metal ion binding, metallodipeptidase activity, metallopeptidase activity, peptidase activity; CC: cytopl...
Does Knockout of Col6a4 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Col6a4
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Col6a4 (collagen, type VI, alpha 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, extracellular matrix organization; MF: collagen binding, extracellular matrix structural constituent conferring tensile strength; CC: collagen trimer, collagen type VI...
Does Knockout of Iffo2 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Iffo2
protein/peptide distribution
myoblast cell line
Gene: Iffo2 (intermediate filament family orphan 2) Type: protein-coding Summary: Predicted to be located in intermediate filament. Is expressed in 4th ventricle; axial skeleton; choroid plexus; lateral ventricle choroid plexus; and rib. Orthologous to human IFFO2 (intermediate filament family orphan 2)...
Does Knockout of Cnpy1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Cnpy1
cell proliferation
Mouse kidney carcinoma cell
Gene: Cnpy1 (canopy FGF signaling regulator 1) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q4VAB4 Entrez ID: 269637
Does Knockout of Ube2ql1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Ube2ql1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ube2ql1 (ubiquitin-conjugating enzyme E2Q family-like 1) Type: protein-coding Summary: Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein polyubiquitination. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be active in nucleus. I...
Does Knockout of Add2 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Add2
protein/peptide distribution
Microglial Cell Line
Gene: Add2 (adducin 2) Type: protein-coding Summary: This gene encodes the beta subunit of the adducin family. Adducins, encoded by alpha, beta and gamma genes, are heteromeric proteins that crosslink actin filaments with spectrin at the cytoskeletal membrane. This protein, primarily found in the brain ...
Does Knockout of Pcsk6 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
163
Knockout
Pcsk6
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Pcsk6 (proprotein convertase subtilisin/kexin type 6) Type: protein-coding Summary: Predicted to enable heparin binding activity; nerve growth factor binding activity; and serine-type endopeptidase activity. Acts upstream of or within determination of left/right symmetry; protein processing; and z...
Does Knockout of Rnls in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Rnls
cell proliferation
Colonic Cancer Cell Line
Gene: Rnls (renalase, FAD-dependent amine oxidase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cardiac left ventricle morphogenesis, dopamine metabolic process, epinephrine metabolic process, heart contraction, negative regulation of blood pressure, negative regulatio...
Does Knockout of Uqcr10 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,259
Knockout
Uqcr10
cell proliferation
Mouse kidney carcinoma cell
Gene: Uqcr10 (ubiquinol-cytochrome c reductase, complex III subunit X) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular respiration, mitochondrial electron transport, ubiquinol to cytochrome c; CC: membrane, mitochondrial inner membrane, mitochondrion, respiratory...
Does Knockout of Dleu7 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Dleu7
cell proliferation
Colonic Cancer Cell Line
Gene: Dleu7 (deleted in lymphocytic leukemia, 7) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8CHZ8 Entrez ID: 239133
Does Knockout of Timm17a in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Timm17a
protein/peptide distribution
Microglial Cell Line
Gene: Timm17a (translocase of inner mitochondrial membrane 17a) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of protein processing, protein import into mitochondrial matrix, protein transport; MF: enzyme binding, protein transmembrane transporter ac...
Does Knockout of Mbd3l2 in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
Mbd3l2
cell proliferation
Melanoma Cell Line
Gene: Mbd3l2 (methyl-CpG binding domain protein 3-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA methylation-dependent constitutive heterochromatin formation, biological_process, negative regulation of transcription by RNA polymerase II; MF: methyl-CpG bindin...
Does Knockout of Cyp4a31 in Microglial Cell Line causally result in phagocytosis?
0
1,587
Knockout
Cyp4a31
phagocytosis
Microglial Cell Line
Gene: Cyp4a31 (cytochrome P450, family 4, subfamily a, polypeptide 31) Type: protein-coding Summary: No summary available. Gene Ontology: BP: arachidonate metabolic process, fatty acid metabolic process, icosanoid biosynthetic process, kidney development, lauric acid metabolic process, linoleic...
Does Knockout of Commd7 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Commd7
cell proliferation
Mouse kidney carcinoma cell
Gene: Commd7 (COMM domain containing 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA-templated transcription, tumor necrosis factor-mediated signaling pathway; MF: NF-kappaB binding Pathways: Metabolism of proteins, Neddylation, Post...
Does Knockout of P2rx3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
P2rx3
cell proliferation
Mouse kidney carcinoma cell
Gene: P2rx3 (purinergic receptor P2X, ligand-gated ion channel, 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: behavioral response to formalin induced pain, behavioral response to pain, calcium ion transmembrane transport, cellular response to ATP, chemical synaptic t...
Does Knockout of BC004004 in Embryonic Fibroblast Cell Line causally result in cell proliferation?
0
345
Knockout
BC004004
cell proliferation
Embryonic Fibroblast Cell Line
Gene: BC004004 (cDNA sequence BC004004) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagy, chromatin remodeling, collagen metabolic process, connective tissue replacement, epithelial cell proliferation, fibroblast proliferation, positive regulation of cell cycle, ...
Does Knockout of Cldn34b4 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Cldn34b4
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cldn34b4 (claudin 34B4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bicellular tight junction assembly, cell adhesion; MF: molecular_function, structural molecule activity; CC: anchoring junction, bicellular tight junction, membrane, plasma membrane Pat...
Does Knockout of Tenm2 in myoblast cell line causally result in protein/peptide distribution?
0
1,685
Knockout
Tenm2
protein/peptide distribution
myoblast cell line
Gene: Tenm2 (teneurin transmembrane protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cell-cell adhesion, negative regulation of transcription by RNA polymerase II, neuron development, positive regulation of filopodium assembly, retrograde trans-sy...
Does Knockout of Tmem255a in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Tmem255a
response to virus
Embryonic Fibroblast Cell Line
Gene: Tmem255a (transmembrane protein 255A) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q8BHW5 Entrez ID: 245386
Does Knockout of Mis18a in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Mis18a
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Mis18a (MIS18 kinetochore protein A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CENP-A containing chromatin assembly, cell division, chromosome segregation, heterochromatin formation, pericentric heterochromatin organization, protein localization to chromosome,...
Does Knockout of Bin2 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Bin2
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Bin2 (bridging integrator 2) Type: protein-coding Summary: Predicted to enable phospholipid binding activity. Predicted to be involved in several processes, including phagocytosis, engulfment; plasma membrane tubulation; and podosome assembly. Predicted to be located in anchoring junction; cell co...
Does Knockout of Igsf9 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Igsf9
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Igsf9 (immunoglobulin superfamily, member 9) Type: protein-coding Summary: Enables cell-cell adhesion mediator activity. Acts upstream of or within dendrite development; homophilic cell adhesion via plasma membrane adhesion molecules; and regulation of synapse organization. Located in axon; dendri...
Does Knockout of Pnrc2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Pnrc2
cell proliferation
Mouse kidney carcinoma cell
Gene: Pnrc2 (proline-rich nuclear receptor coactivator 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; CC: Golgi apparatus, P-body, cytoplasm, nucleoplasm, nucleus Pat...
Does Knockout of Tmem45a2 in macrophage causally result in phagocytosis?
0
1,890
Knockout
Tmem45a2
phagocytosis
macrophage
Gene: Tmem45a2 (transmembrane protein 45A2) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q8CEZ6, B7ZWJ5 Entrez ID: 69457
Does Knockout of Lima1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Lima1
protein/peptide accumulation
Embryonic Cell Line
Gene: Lima1 (LIM domain and actin binding 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament bundle assembly, cell migration, cholesterol homeostasis, cholesterol metabolic process, intestinal cholesterol absorption, lipid metabolic process, negative regula...
Does Knockout of Zbtb8b in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Zbtb8b
cell proliferation
Melanoma Cell Line
Gene: Zbtb8b (zinc finger and BTB domain containing 8b) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, metal ion binding, zinc ion binding; CC: cytosol, nucleoplasm, nucleus Path...
Does Knockout of Dcun1d1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Dcun1d1
cell proliferation
Mouse kidney carcinoma cell
Gene: Dcun1d1 (defective in cullin neddylation 1 domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of protein neddylation, protein neddylation, regulation of protein neddylation, regulation of protein ubiquitination; MF: cullin famil...
Does Knockout of Top2a in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,276
Knockout
Top2a
cell proliferation
Colonic Cancer Cell Line
Gene: Top2a (topoisomerase (DNA) II alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA metabolic process, DNA topological change, apoptotic chromosome condensation, chromatin organization, chromosome condensation, chromosome segregation, embry...
Does Knockout of Pex2 in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Pex2
response to virus
Neuroblastoma Cell Line
Gene: Pex2 (peroxisomal biogenesis factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bile acid biosynthetic process, cellular response to reactive oxygen species, cholesterol homeostasis, fatty acid beta-oxidation, negative regulation of epithelial cell proliferat...
Does Knockout of Kcnk6 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Kcnk6
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Kcnk6 (potassium inwardly-rectifying channel, subfamily K, member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transmembrane transport, monoatomic ion transport, negative regulation of systemic arterial blood pressure, positive regulation of NLR...
Does Knockout of Pick1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Pick1
cell proliferation
Mouse kidney carcinoma cell
Gene: Pick1 (protein interacting with C kinase 1) Type: protein-coding Summary: Enables protein kinase C binding activity and signaling receptor binding activity. Involved in receptor clustering. Acts upstream of or within protein targeting. Located in several cellular components, including Golgi appara...
Does Knockout of Slc30a5 in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Slc30a5
response to virus
Neuroblastoma Cell Line
Gene: Slc30a5 (solute carrier family 30 (zinc transporter), member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GPI anchor biosynthetic process, cobalt ion transport, insulin processing, intracellular zinc ion homeostasis, monoatomic cation transport, monoatomic ion...
Does Knockout of Pcgf6 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Pcgf6
protein/peptide distribution
myoblast cell line
Gene: Pcgf6 (polycomb group ring finger 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin remodeling, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II...
Does Knockout of Spata20 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Spata20
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Spata20 (spermatogenesis associated 20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate metabolic process, cell differentiation, spermatogenesis Pathways: UniProt: Q80YT5 Entrez ID: 217116
Does Knockout of Sirt6 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Sirt6
cell proliferation
Mouse kidney carcinoma cell
Gene: Sirt6 (sirtuin 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, Ras protein signal transduction, base-excision repair, cardiac muscle cell differentiation, cellular response to angiotensin...
Does Knockout of Tmem97 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Tmem97
protein/peptide accumulation
Embryonic Cell Line
Gene: Tmem97 (transmembrane protein 97) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cholesterol homeostasis, positive regulation of lipoprotein transport, positive regulation of wound healing, regulation of intracellular cholesterol transport, regulation of intracellu...
Does Knockout of Tbxas1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Tbxas1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tbxas1 (thromboxane A synthase 1, platelet) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fatty acid biosynthetic process, fatty acid metabolic process, icosanoid metabolic process, intracellular chloride ion homeostasis, lipid metabolic process, long-chain fatty ...
Does Knockout of Usp18 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Usp18
cell proliferation
Colonic Cancer Cell Line
Gene: Usp18 (ubiquitin specific peptidase 18) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antiviral innate immune response, negative regulation of type I interferon-mediated signaling pathway, protein deubiquitination, proteolysis, regulation of inflammatory response,...
Does Knockout of Defb48 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Defb48
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Defb48 (defensin beta 48) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell chemotaxis, defense response, defense response to bacterium, positive chemotaxis; MF: CCR6 chemokine receptor binding, chemoattractant activity; CC: extracellular region, extracellular sp...
Does Knockout of Abca3 in Regulatory T cell causally result in cell proliferation?
0
1,483
Knockout
Abca3
cell proliferation
Regulatory T cell
Gene: Abca3 (ATP-binding cassette, sub-family A member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intermembrane lipid transfer, lipid translocation, lipid transport, lung development, organelle assembly, phosphatidylcholine metabolic process, phosphatidylglycerol ...
Does Knockout of Unc5b in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Unc5b
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Unc5b (unc-5 netrin receptor B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, anterior/posterior axon guidance, apoptotic process, axon guidance, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, negative regulation o...
Does Knockout of Sox13 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Sox13
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Sox13 (SRY (sex determining region Y)-box 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cell fate commitment, gamma-delta T cell differentiation, negative regulation of DNA-templated transcription, negative regulation of canonical Wnt sig...
Does Knockout of Sgip1 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Sgip1
protein/peptide distribution
myoblast cell line
Gene: Sgip1 (SH3-domain GRB2-like (endophilin) interacting protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: clathrin-dependent endocytosis, endocytosis, energy homeostasis, plasma membrane tubulation, positive regulation of eating behavior, positive regulation o...
Does Knockout of Gm10840 in Melanoma Cell Line causally result in cell proliferation?
0
1,282
Knockout
Gm10840
cell proliferation
Melanoma Cell Line
Gene: Gm10840 (predicted gene 10840) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Uqcr10 in macrophage causally result in response to bacteria?
0
2,211
Knockout
Uqcr10
response to bacteria
macrophage
Gene: Uqcr10 (ubiquinol-cytochrome c reductase, complex III subunit X) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular respiration, mitochondrial electron transport, ubiquinol to cytochrome c; CC: membrane, mitochondrial inner membrane, mitochondrion, respiratory...
Does Knockout of Gm5797 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Gm5797
cell viability
Immortal mouse chromaffin cells
Gene: Gm5797 (predicted gene 5797) Type: protein-coding Summary: predicted gene 5797 Gene Ontology: Pathways: UniProt: Q5BKP9 Entrez ID: 545013
Does Knockout of Rsbn1 in myoblast cell line causally result in protein/peptide distribution?
0
1,683
Knockout
Rsbn1
protein/peptide distribution
myoblast cell line
Gene: Rsbn1 (rosbin, round spermatid basic protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, chromatin organization, chromatin remodeling; MF: dioxygenase activity, histone H4K20 demethylase activity, metal ion binding, oxidoreductase activity...
Does Knockout of Nedd4l in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
163
Knockout
Nedd4l
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Nedd4l (neural precursor cell expressed, developmentally down-regulated gene 4-like) Type: protein-coding Summary: Enables sodium channel inhibitor activity and ubiquitin protein ligase activity. Involved in regulation of postsynaptic neurotransmitter receptor internalization; regulation protein c...
Does Knockout of Cacna1c in Melanoma Cell Line causally result in cell proliferation?
0
2,488
Knockout
Cacna1c
cell proliferation
Melanoma Cell Line
Gene: Cacna1c (calcium channel, voltage-dependent, L type, alpha 1C subunit) Type: protein-coding Summary: Enables enzyme binding activity and voltage-gated calcium channel activity involved in cardiac muscle cell action potential. Involved in positive regulation of adenylate cyclase activity. Acts upst...
Does Knockout of Vmn2r45 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Vmn2r45
cell cycle progression
breast epithelium
Gene: Vmn2r45 (vomeronasal 2, receptor 45) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: UniProt: L7N2B...
Does Knockout of Ppy in myoblast cell line causally result in protein/peptide distribution?
1
1,680
Knockout
Ppy
protein/peptide distribution
myoblast cell line
Gene: Ppy (pancreatic polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: feeding behavior, neuropeptide signaling pathway; MF: G protein-coupled receptor binding, hormone activity, neuropeptide Y receptor binding, neuropeptide hormone activity; CC: cytoplasm, ex...
Does Knockout of Ntrk1 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Ntrk1
protein/peptide distribution
myoblast cell line
Gene: Ntrk1 (neurotrophic tyrosine kinase, receptor, type 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, Sertoli cell development, axon guidance, axonogenesis involved in innervation, behavioral response to formalin induced pain, cell different...
Does Knockout of Ighv1-12 in macrophage causally result in phagocytosis?
0
1,890
Knockout
Ighv1-12
phagocytosis
macrophage
Gene: Ighv1-12 (immunoglobulin heavy variable V1-12) Type: other Summary: No summary available. Gene Ontology: BP: adaptive immune response, immune system process, immunoglobulin mediated immune response; CC: extracellular region, immunoglobulin complex Pathways: UniProt: ...
Does Knockout of Hsd3b7 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Hsd3b7
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Hsd3b7 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell chemotaxis, cholesterol catabolic process, lipid metabolic process, regulation of cell growth, steroid biosynthetic process; ...
Does Knockout of Pou2f1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Pou2f1
cell proliferation
Embryonic Stem Cell Line
Gene: Pou2f1 (POU domain, class 2, transcription factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lens induction in camera-type eye, negative regulation of DNA-templated transcription, negative regulation of miRNA transcription, olfactory placode formation, posit...
Does Knockout of Akr1c19 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Akr1c19
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Akr1c19 (aldo-keto reductase family 1, member C19) Type: protein-coding Summary: No summary available. Gene Ontology: BP: daunorubicin metabolic process, doxorubicin metabolic process, progesterone metabolic process, prostaglandin metabolic process; MF: 15-hydroxyprostaglandin-D dehydroge...
Does Knockout of Oscar in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Oscar
protein/peptide accumulation
Embryonic Cell Line
Gene: Oscar (osteoclast associated receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Fc-gamma receptor signaling pathway, collagen-activated signaling pathway, immune response-regulating signaling pathway, multinuclear osteoclast differentiation, osteoclast differ...
Does Knockout of Kcnk7 in macrophage causally result in phagocytosis?
0
1,890
Knockout
Kcnk7
phagocytosis
macrophage
Gene: Kcnk7 (potassium channel, subfamily K, member 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion transmembrane transport, potassium ion transport; MF: outward rectifier potassium channel...
Does Knockout of Sash3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Sash3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Sash3 (SAM and SH3 domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell homeostasis, homeostasis of number of cells within a tissue, positive regulation of B cell proliferation, positive regulation of CD4-positive, alpha-beta T cell differenti...
Does Knockout of Grin1os in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Grin1os
response to chemicals
Pancreatic Cancer Cell Line
Gene: Grin1os (glutamate receptor, ionotropic, NMDA1 (zeta 1), opposite strand) Type: ncRNA Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 320354
Does Knockout of Pcbp4 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Pcbp4
cell proliferation
Mouse kidney carcinoma cell
Gene: Pcbp4 (poly(rC) binding protein 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulation of mRNA splicing, via spliceosome, regulation of gene expression, regulation...
Does Knockout of Ndufc1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ndufc1
cell proliferation
Embryonic Stem Cell Line
Gene: Ndufc1 (NADH:ubiquinone oxidoreductase subunit C1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner membrane, mitochondrion, respiratory chain complex I ...
Does Knockout of Cep72 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Cep72
protein/peptide accumulation
Mouse cell
Gene: Cep72 (centrosomal protein 72) Type: protein-coding Summary: No summary available. Gene Ontology: BP: centriole replication, gamma-tubulin complex localization, regulation of protein localization to centrosome, spindle organization; CC: centriolar satellite, centrosome, ciliary basal body...
Does Knockout of Agbl2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
1,565
Knockout
Agbl2
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Agbl2 (ATP/GTP binding protein-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein side chain deglutamylation, proteolysis; MF: carboxypeptidase activity, hydrolase activity, metal ion binding, metallocarboxypeptidase activity, metallopeptidase activity,...