prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of Akirin2 in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 579 | Knockout | Akirin2 | cell proliferation | Embryonic Stem Cell Line | Gene: Akirin2 (akirin 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: adaptive immune response, cerebral cortex development, defense response to bacterium, embryo development ending in birth or egg hatching, immune system process, innate immune response, negative regul... |
Does Knockout of Fmr1nb in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,262 | Knockout | Fmr1nb | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Fmr1nb (Fmr1 neighbor)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q80ZA7
Entrez ID: 207854 |
Does Knockout of Canx in breast epithelium causally result in cell cycle progression? | 0 | 1,469 | Knockout | Canx | cell cycle progression | breast epithelium | Gene: Canx (calnexin)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ERAD pathway, clathrin-dependent endocytosis, protein folding, synaptic vesicle endocytosis; MF: apolipoprotein binding, calcium ion binding, carbohydrate binding, ionotropic glutamate receptor binding,... |
Does Knockout of Unc50 in Embryonic Fibroblast Cell Line causally result in cell proliferation? | 0 | 345 | Knockout | Unc50 | cell proliferation | Embryonic Fibroblast Cell Line | Gene: Unc50 (unc-50 homolog)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein localization to cell surface; MF: RNA binding; CC: Golgi apparatus, Golgi membrane, membrane, nuclear inner membrane, nucleus
Pathways:
UniProt: Q9CQ61
Entrez I... |
Does Knockout of H2-DMb1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 84 | Knockout | H2-DMb1 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: H2-DMb1 (histocompatibility 2, class II, locus Mb1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: MHC class II protein complex assembly, adaptive immune response, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen... |
Does Knockout of Cdh23 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity? | 0 | 2,175 | Knockout | Cdh23 | tumorigenicity | Breast Adenocarcinoma Cell Line | Gene: Cdh23 (cadherin related 23 (otocadherin))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: auditory receptor cell stereocilium organization, calcium ion transport, calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, cell adhesion, cell m... |
Does Knockout of Serpinb6d in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,684 | Knockout | Serpinb6d | protein/peptide distribution | myoblast cell line | Gene: Serpinb6d (serine (or cysteine) peptidase inhibitor, clade B, member 6d)
Type: protein-coding
Summary: This gene is a member of the large Serpin gene family. Many members of this family act as protease inhibitors, and have a conserved structure including a reactive center loop (RCL) that can act a... |
Does Knockout of Rnf113a1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 165 | Knockout | Rnf113a1 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Rnf113a1 (ring finger protein 113A1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mRNA splicing, via spliceosome, negative regulation of chemokine-mediated signaling pathway, protein ubiquitination, snoRNA splicing; MF: metal ion binding, ubiquitin protein ligase... |
Does Knockout of Tbc1d10c in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 0 | 2,188 | Knockout | Tbc1d10c | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: Tbc1d10c (TBC1 domain family, member 10c)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of B cell activation, negative regulation of ERK1 and ERK2 cascade, negative regulation of calcineurin-NFAT signaling cascade, retrograde transport, endosom... |
Does Knockout of Dpf1 in macrophage causally result in phagocytosis? | 0 | 1,888 | Knockout | Dpf1 | phagocytosis | macrophage | Gene: Dpf1 (double PHD fingers 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin remodeling, nervous system development, positive regulation of cell differentiation, positive regulation of double-strand break repair, regulation of G0 to G1 transition, regulatio... |
Does Knockout of Dhx40 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 161 | Knockout | Dhx40 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Dhx40 (DEAH-box helicase 40)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: 3'-5' RNA helicase activity, ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase activity, hydrolase activity, nucleic acid binding, nucleotide binding
... |
Does Knockout of Nhlrc1 in Melanoma Cell Line causally result in cell proliferation? | 0 | 1,269 | Knockout | Nhlrc1 | cell proliferation | Melanoma Cell Line | Gene: Nhlrc1 (NHL repeat containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: autophagy, glycogen biosynthetic process, glycogen metabolic process, positive regulation of protein ubiquitination, proteasome-mediated ubiquitin-dependent protein catabolic process, p... |
Does Knockout of Pou3f3 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,290 | Knockout | Pou3f3 | cell proliferation | Mouse kidney carcinoma cell | Gene: Pou3f3 (POU domain, class 3, transcription factor 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: brain development, cerebral cortex radially oriented cell migration, chemical homeostasis, forebrain ventricular zone progenitor cell division, kidney development, m... |
Does Knockout of St8sia4 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,681 | Knockout | St8sia4 | protein/peptide distribution | myoblast cell line | Gene: St8sia4 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: N-glycan processing, ganglioside biosynthetic process, oligosaccharide metabolic process, protein glycosylation, sialylation; MF: alpha-N-acetylneu... |
Does Knockout of Psd in macrophage causally result in response to bacteria? | 0 | 2,211 | Knockout | Psd | response to bacteria | macrophage | Gene: Psd (pleckstrin and Sec7 domain containing)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: maintenance of postsynaptic density structure, neuron projection development, regulation of ARF protein signal transduction, regulation of postsynapse assembly; MF: guanyl-nu... |
Does Knockout of Asf1a in Lymphoma Cell Line causally result in response to chemicals? | 0 | 1,546 | Knockout | Asf1a | response to chemicals | Lymphoma Cell Line | Gene: Asf1a (anti-silencing function 1A histone chaperone)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, DNA replication-dependent chromatin assembly, chromatin organization, double-strand break... |
Does Knockout of Phox2b in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 2,477 | Knockout | Phox2b | cell proliferation | Embryonic Stem Cell Line | Gene: Phox2b (paired-like homeobox 2b)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: autonomic nervous system development, brainstem development, cell development, cell differentiation in hindbrain, cellular response to BMP stimulus, cellular response to carbon dioxide,... |
Does Knockout of Fabp5 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,261 | Knockout | Fabp5 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Fabp5 (fatty acid binding protein 5, epidermal)
Type: protein-coding
Summary: The protein encoded by this gene is part of the fatty acid binding protein family (FABP). FABPs are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands... |
Does Knockout of Pkn2 in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 579 | Knockout | Pkn2 | cell proliferation | Embryonic Stem Cell Line | Gene: Pkn2 (protein kinase N2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apical junction assembly, apoptotic process, cell adhesion, cell division, cell projection organization, epithelial cell migration, intracellular signal transduction, positive regulation of cyt... |
Does Knockout of Jrkl in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,260 | Knockout | Jrkl | cell proliferation | Mouse kidney carcinoma cell | Gene: Jrkl (Jrk-like)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: DNA binding, molecular_function, nucleic acid binding; CC: nucleus
Pathways:
UniProt: B2RRL2
Entrez ID: 77532 |
Does Knockout of Map10 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 1,152 | Knockout | Map10 | protein/peptide accumulation | Embryonic Cell Line | Gene: Map10 (microtubule-associated protein 10)
Type: protein-coding
Summary: Predicted to enable microtubule binding activity. Predicted to be involved in microtubule cytoskeleton organization; positive regulation of cytokinesis; and regulation of microtubule-based process. Predicted to be active in mi... |
Does Knockout of Egr1 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,260 | Knockout | Egr1 | cell proliferation | Mouse kidney carcinoma cell | Gene: Egr1 (early growth response 1)
Type: protein-coding
Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and enzyme binding activity. Involved in several processes, including cellu... |
Does Knockout of Tbc1d10c in Non-Small Cell Lung Cancer Cell Line causally result in tumorigenicity? | 0 | 2,189 | Knockout | Tbc1d10c | tumorigenicity | Non-Small Cell Lung Cancer Cell Line | Gene: Tbc1d10c (TBC1 domain family, member 10c)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of B cell activation, negative regulation of ERK1 and ERK2 cascade, negative regulation of calcineurin-NFAT signaling cascade, retrograde transport, endosom... |
Does Knockout of Cd22 in Neuroblastoma Cell Line causally result in response to virus? | 0 | 1,422 | Knockout | Cd22 | response to virus | Neuroblastoma Cell Line | Gene: Cd22 (CD22 antigen)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: B cell activation, cell adhesion, cell surface receptor signaling pathway, negative regulation of B cell receptor signaling pathway, negative regulation of calcium-mediated signaling, negative regul... |
Does Knockout of Trpc1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 687 | Knockout | Trpc1 | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Trpc1 (transient receptor potential cation channel, subfamily C, member 1)
Type: protein-coding
Summary: Enables store-operated calcium channel activity. Acts upstream of or within saliva secretion. Located in basolateral plasma membrane; membrane raft; and myofibril. Part of protein-containing co... |
Does Knockout of Kcns1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 83 | Knockout | Kcns1 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Kcns1 (K+ voltage-gated channel, subfamily S, 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: action potential, monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion transmembrane transport, potassium ion transport, protein homooligomeri... |
Does Knockout of Lonrf1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,280 | Knockout | Lonrf1 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Lonrf1 (LON peptidase N-terminal domain and ring finger 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: metal ion binding, zinc ion binding
Pathways: Adaptive Immune System, Antigen processing: Ubiquitination & Proteasome degradation, Class I MHC mediate... |
Does Knockout of Zcchc2 in pro-B-lymphocyte causally result in response to chemicals? | 0 | 1,720 | Knockout | Zcchc2 | response to chemicals | pro-B-lymphocyte | Gene: Zcchc2 (zinc finger, CCHC domain containing 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: metal ion binding, molecular_function, nucleic acid binding, phosphatidylinositol binding, zinc ion binding; CC: cytoplasm
Pathways:
UniProt: Q69ZB8
... |
Does Knockout of Numb in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,263 | Knockout | Numb | cell proliferation | Colonic Cancer Cell Line | Gene: Numb (NUMB endocytic adaptor protein)
Type: protein-coding
Summary: This gene encodes a conserved protein that is distributed asymmetrically during cell division in the developing embryo. The encoded protein participates in cell fate decisions by interacting with the Notch receptor. Loss of functi... |
Does Knockout of Cep83 in macrophage causally result in phagocytosis? | 0 | 1,889 | Knockout | Cep83 | phagocytosis | macrophage | Gene: Cep83 (centrosomal protein 83)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell projection organization, cilium assembly, establishment of centrosome localization, protein localization to centrosome, vesicle docking; CC: Golgi apparatus, centriole, centrosome, c... |
Does Knockout of Caprin2 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,263 | Knockout | Caprin2 | cell proliferation | Colonic Cancer Cell Line | Gene: Caprin2 (caprin family member 2)
Type: protein-coding
Summary: This gene encodes a member of the caprin family. The encoded protein may function as an RNA-binding protein that induces the formation of RNA granules and plays an important role in brain function. Alternative splicing results in multi... |
Does Knockout of Mturn in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 81 | Knockout | Mturn | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Mturn (maturin, neural progenitor differentiation regulator homolog (Xenopus))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of NF-kappaB transcription factor activity, neuron development, positive regulation of ERK1 and ERK2 cascade, positive ... |
Does Knockout of Stat1 in Mouse kidney carcinoma cell causally result in cell proliferation? | 1 | 1,283 | Knockout | Stat1 | cell proliferation | Mouse kidney carcinoma cell | Gene: Stat1 (signal transducer and activator of transcription 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA-templated transcription, blood circulation, cell population proliferation, cell surface receptor signaling pathway via JAK-STAT, cell surface receptor sign... |
Does Knockout of Vmn1r101 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,680 | Knockout | Vmn1r101 | protein/peptide distribution | myoblast cell line | Gene: Vmn1r101 (vomeronasal 1 receptor 101)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled recepto... |
Does Knockout of Fam174b in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 2,477 | Knockout | Fam174b | cell proliferation | Embryonic Stem Cell Line | Gene: Fam174b (family with sequence similarity 174, member B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Golgi organization; CC: Golgi apparatus, membrane, plasma membrane
Pathways:
UniProt: Q8K064
Entrez ID: 100038347 |
Does Knockout of Prickle4 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,284 | Knockout | Prickle4 | cell proliferation | Mouse kidney carcinoma cell | Gene: Prickle4 (prickle planar cell polarity protein 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: actin cytoskeleton organization, heart development, muscle structure development; MF: actin binding, muscle alpha-actinin binding; CC: Z disc, adherens junction, filame... |
Does Knockout of Sele in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 687 | Knockout | Sele | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Sele (selectin, endothelial cell)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: actin filament-based process, cell adhesion, heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, leukocyte cell-cell adhesion, leukocyte tethering or rolling, ... |
Does Knockout of Tnfrsf17 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,679 | Knockout | Tnfrsf17 | protein/peptide distribution | myoblast cell line | Gene: Tnfrsf17 (tumor necrosis factor receptor superfamily, member 17)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: adaptive immune response, immune system process, lymphocyte homeostasis, tumor necrosis factor-mediated signaling pathway
Pathways: Cytokine Sig... |
Does Knockout of Prorsd1 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,263 | Knockout | Prorsd1 | cell proliferation | Colonic Cancer Cell Line | Gene: Prorsd1 (prolyl-tRNA synthetase domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: aminoacyl-tRNA metabolism involved in translational fidelity, biological_process, tRNA metabolic process; MF: aminoacyl-tRNA deacylase activity, molecular_function
... |
Does Knockout of Camk2d in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,663 | Knockout | Camk2d | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Camk2d (calcium/calmodulin-dependent protein kinase II, delta)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G1/S transition of mitotic cell cycle, calcium ion transport, cardiac muscle cell contraction, cardiac muscle contraction, cell growth involved in cardiac ... |
Does Knockout of Krt8 in Melanoma Cell Line causally result in cell proliferation? | 0 | 1,270 | Knockout | Krt8 | cell proliferation | Melanoma Cell Line | Gene: Krt8 (keratin 8)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell differentiation involved in embryonic placenta development, extrinsic apoptotic signaling pathway, hepatocyte apoptotic process, response to hydrostatic pressure, response to other organism, sarco... |
Does Knockout of Parva in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,276 | Knockout | Parva | cell proliferation | Colonic Cancer Cell Line | Gene: Parva (parvin, alpha)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: actin cytoskeleton organization, actin filament-based process, actin-mediated cell contraction, angiogenesis, cell adhesion, cell projection organization, chemotaxis, cilium assembly, establishmen... |
Does Knockout of Rps19bp1 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,285 | Knockout | Rps19bp1 | cell proliferation | Mouse kidney carcinoma cell | Gene: Rps19bp1 (ribosomal protein S19 binding protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, ribosomal small subunit biogenesis; MF: enzyme binding, protein binding; CC: cytosol, nucleolus, nucleoplasm, nucleus, small-subunit processome
... |
Does Knockout of Vmn1r65 in Regulatory T cell causally result in cell proliferation? | 0 | 1,483 | Knockout | Vmn1r65 | cell proliferation | Regulatory T cell | Gene: Vmn1r65 (vomeronasal 1 receptor 65)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor ... |
Does Knockout of Zfp458 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,276 | Knockout | Zfp458 | cell proliferation | Colonic Cancer Cell Line | Gene: Zfp458 (zinc finger protein 458)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of DNA-templated transcription, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: metal ion binding, sequence-specific... |
Does Knockout of Nxph2 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,680 | Knockout | Nxph2 | protein/peptide distribution | myoblast cell line | Gene: Nxph2 (neurexophilin 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: signaling receptor binding
Pathways:
UniProt: Q61199
Entrez ID: 18232 |
Does Knockout of Zfp457 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,267 | Knockout | Zfp457 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Zfp457 (zinc finger protein 457)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, metal ion bindin... |
Does Knockout of Zbtb14 in Microglial Cell Line causally result in response to virus? | 0 | 2,429 | Knockout | Zbtb14 | response to virus | Microglial Cell Line | Gene: Zbtb14 (zinc finger and BTB domain containing 14)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cardiac septum development, coronary vasculature development, heart valve development, kidney development, negative regulation of DNA-templated transcription, negative ... |
Does Knockout of Alg9 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 2,173 | Knockout | Alg9 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Alg9 (ALG9 alpha-1,2-mannosyltransferase)
Type: protein-coding
Summary: Predicted to enable dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity and dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity. Predicted to be involved in dolichol-linked oligosacchari... |
Does Knockout of Gde1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 167 | Knockout | Gde1 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Gde1 (glycerophosphodiester phosphodiesterase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, N-acylethanolamine metabolic process, ethanolamine metabolic process, lipid metabolic process, phospholipid metabolic proce... |
Does Knockout of Arpc3 in Regulatory T cell causally result in protein/peptide accumulation? | 0 | 1,482 | Knockout | Arpc3 | protein/peptide accumulation | Regulatory T cell | Gene: Arpc3 (actin related protein 2/3 complex, subunit 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Arp2/3 complex-mediated actin nucleation, regulation of actin filament polymerization, regulation of synaptic vesicle endocytosis; MF: actin binding, actin filament ... |
Does Knockout of Borcs5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 82 | Knockout | Borcs5 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Borcs5 (BLOC-1 related complex subunit 5)
Type: protein-coding
Summary: Acts upstream of or within nervous system development and organelle transport along microtubule. Is active in axon and lysosome. Is expressed in brain; heart; lung; and metanephros. Human ortholog(s) of this gene implicated in... |
Does Knockout of 2310061I04Rik in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,289 | Knockout | 2310061I04Rik | cell proliferation | Mouse kidney carcinoma cell | Gene: 2310061I04Rik (RIKEN cDNA 2310061I04 gene)
Type: protein-coding
Summary: Located in mitochondrion. Is expressed in several structures, including adrenal gland; gonad; liver; lung; and spleen. Orthologous to human C6orf136 (chromosome 6 open reading frame 136). [provided by Alliance of Genome Resou... |
Does Knockout of 6030469F06Rik in Melanoma Cell Line causally result in cell proliferation? | 0 | 1,269 | Knockout | 6030469F06Rik | cell proliferation | Melanoma Cell Line | Gene: 6030469F06Rik (RIKEN cDNA 6030469F06 gene)
Type: ncRNA
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt:
Entrez ID: 100043065 |
Does Knockout of Ebf4 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation? | 0 | 1,077 | Knockout | Ebf4 | protein/peptide accumulation | Mouse Embryonic Stem Cell | Gene: Ebf4 (early B cell factor 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: T cell apoptotic process, positive regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA bin... |
Does Knockout of Cetn2 in Lymphoma Cell Line causally result in response to chemicals? | 0 | 1,523 | Knockout | Cetn2 | response to chemicals | Lymphoma Cell Line | Gene: Cetn2 (centrin 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, cell division, centriole replication, mRNA transport, microtubule cytoskeleton organization, nucleotide-excision repair, protein transport, regulation of cytokinesis, ... |
Does Knockout of Foxo6 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 84 | Knockout | Foxo6 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Foxo6 (forkhead box O6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: memory, positive regulation of dendritic spine development, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcriptio... |
Does Knockout of Dlx2 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,272 | Knockout | Dlx2 | cell proliferation | Mouse kidney carcinoma cell | Gene: Dlx2 (distal-less homeobox 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: GABAergic neuron differentiation, branching morphogenesis of a nerve, cartilage development, cell differentiation, cerebral cortex GABAergic interneuron differentiation, cerebral cortex GA... |
Does Knockout of Inpp4b in Melanoma Cell Line causally result in cell proliferation? | 0 | 2,492 | Knockout | Inpp4b | cell proliferation | Melanoma Cell Line | Gene: Inpp4b (inositol polyphosphate-4-phosphatase, type II)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: intracellular calcium ion homeostasis, lipid metabolic process, negative regulation of osteoclast differentiation, phosphatidylinositol dephosphorylation, phosphat... |
Does Knockout of Fbxw25 in macrophage causally result in phagocytosis? | 0 | 1,889 | Knockout | Fbxw25 | phagocytosis | macrophage | Gene: Fbxw25 (F-box and WD-40 domain protein 25)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: cellular_component, cytoplasm
Pathways:
UniProt: F7C9P2
Entrez ID: 546160 |
Does Knockout of Ccnb1 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,680 | Knockout | Ccnb1 | protein/peptide distribution | myoblast cell line | Gene: Ccnb1 (cyclin B1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G1/S transition of mitotic cell cycle, cell division, cellular response to fatty acid, cellular response to hypoxia, cellular response to iron(III) ion, digestive tract development, in utero embryonic... |
Does Knockout of Armcx6 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation? | 0 | 1,077 | Knockout | Armcx6 | protein/peptide accumulation | Mouse Embryonic Stem Cell | Gene: Armcx6 (armadillo repeat containing, X-linked 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: membrane, mitochondrial outer membrane, mitochondrion
Pathways:
UniProt: Q8K3A6
Entrez ID: 278097 |
Does Knockout of Pptc7 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,276 | Knockout | Pptc7 | cell proliferation | Colonic Cancer Cell Line | Gene: Pptc7 (PTC7 protein phosphatase homolog)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitophagy, negative regulation of mitophagy, positive regulation of ubiquinone biosynthetic process, regulation of ubiquinone biosynthetic process; MF: hydrolase activity, metal... |
Does Knockout of Junb in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,663 | Knockout | Junb | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Junb (jun B proto-oncogene)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to calcium ion, decidualization, embryonic process involved in female pregnancy, in utero embryonic development, labyrinthine layer blood vessel development, osteoblast dif... |
Does Knockout of Gpr85 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,261 | Knockout | Gpr85 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Gpr85 (G protein-coupled receptor 85)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: endoplasmic reticulum, membrane, plasma membrane
Pathways: ... |
Does Knockout of Cntn3 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,683 | Knockout | Cntn3 | protein/peptide distribution | myoblast cell line | Gene: Cntn3 (contactin 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell adhesion, neuron projection development; CC: membrane, neuron projection, plasma membrane, side of membrane
Pathways: Metabolism of proteins, Post-translational modification: synthesis... |
Does Knockout of Osgepl1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 2,307 | Knockout | Osgepl1 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: Osgepl1 (O-sialoglycoprotein endopeptidase-like 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: tRNA processing, tRNA threonylcarbamoyladenosine modification; MF: acyltransferase activity, acyltransferase activity, transferring groups other than amino-acyl groups... |
Does Knockout of Spata31 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,261 | Knockout | Spata31 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Spata31 (spermatogenesis associated 31)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, cell differentiation, spermatogenesis; MF: actin binding, molecular_function; CC: acrosomal lumen, acrosomal membrane, acrosomal vesicle, cytoplasmic vesicle,... |
Does Knockout of Sbpl in Melanoma Cell Line causally result in cell proliferation? | 0 | 2,488 | Knockout | Sbpl | cell proliferation | Melanoma Cell Line | Gene: Sbpl (spermine binding protein-like)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, cell migration; MF: carbohydrate binding, molecular_function; CC: apicolateral plasma membrane, cytoplasm, extracellular region, extracellular space, plasma memb... |
Does Knockout of Nlrp4e in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,278 | Knockout | Nlrp4e | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Nlrp4e (NLR family, pyrin domain containing 4E)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: antiviral innate immune response, biological_process, inflammatory response, negative regulation of innate immune response, proteasome-mediated ubiquitin-dependent protei... |
Does Knockout of Naif1 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 1,440 | Knockout | Naif1 | protein/peptide accumulation | Embryonic Cell Line | Gene: Naif1 (nuclear apoptosis inducing factor 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, negative regulation of cell growth, regulation of mitochondrial membrane permeability involved in apoptotic process; CC: cytosol, mitochondrion, nucleoplas... |
Does Knockout of Rec8 in Lymphoma Cell Line causally result in response to chemicals? | 0 | 1,527 | Knockout | Rec8 | response to chemicals | Lymphoma Cell Line | Gene: Rec8 (REC8 meiotic recombination protein)
Type: protein-coding
Summary: Predicted to enable chromatin binding activity. Acts upstream of or within several processes, including germ cell development; meiosis I; and seminiferous tubule development. Located in kinetochore; lateral element; and male g... |
Does Knockout of Cdcp2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,267 | Knockout | Cdcp2 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Cdcp2 (CUB domain containing protein 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: cellular_component, membrane
Pathways:
UniProt: Q8BQH6
Entrez ID: 242603 |
Does Knockout of Chchd3 in Mouse kidney carcinoma cell causally result in cell proliferation? | 1 | 1,289 | Knockout | Chchd3 | cell proliferation | Mouse kidney carcinoma cell | Gene: Chchd3 (coiled-coil-helix-coiled-coil-helix domain containing 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cristae formation, inner mitochondrial membrane organization, mitochondrial fusion; MF: molecular adaptor activity, phosphatase binding, protein binding;... |
Does Knockout of Dlg2 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 1,440 | Knockout | Dlg2 | protein/peptide accumulation | Embryonic Cell Line | Gene: Dlg2 (discs large MAGUK scaffold protein 2)
Type: protein-coding
Summary: A structural constituent of postsynaptic density. Involved in several processes, including axo-dendritic protein transport; clustering of voltage-gated potassium channels; and neurotransmitter receptor localization to postsy... |
Does Knockout of Vti1b in Microglial Cell Line causally result in response to virus? | 0 | 1,439 | Knockout | Vti1b | response to virus | Microglial Cell Line | Gene: Vti1b (vesicle transport through interaction with t-SNAREs 1B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Golgi to vacuole transport, intra-Golgi vesicle-mediated transport, intracellular protein transport, macroautophagy, protein transport, regulation of prote... |
Does Knockout of Arsg in Breast Adenocarcinoma Cell Line causally result in tumorigenicity? | 0 | 2,172 | Knockout | Arsg | tumorigenicity | Breast Adenocarcinoma Cell Line | Gene: Arsg (arylsulfatase G)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: gene expression, glial cell differentiation, homeostasis of number of cells, lysosome organization, neuron apoptotic process, retina development in camera-type eye, sulfur compound metabolic proc... |
Does Knockout of Ccar1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,278 | Knockout | Ccar1 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Ccar1 (cell division cycle and apoptosis regulator 1)
Type: protein-coding
Summary: Enables transcription coactivator activity. Predicted to be involved in positive regulation of cell migration; positive regulation of cell population proliferation; and regulation of DNA-templated transcription. Pr... |
Does Knockout of Zbed5 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,290 | Knockout | Zbed5 | cell proliferation | Mouse kidney carcinoma cell | Gene: Zbed5 (zinc finger BED-type containing 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q8CEW7, B2RPU8, D3Z5B1
Entrez ID: 71970 |
Does Knockout of Zfp770 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 687 | Knockout | Zfp770 | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Zfp770 (zinc finger protein 770)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: DNA binding, metal ion binding, zinc ion binding; CC: nucleus
Pathways: Gene expression (Transcription), Generic Transcription Pathway, RNA Polymerase II Transcription
... |
Does Knockout of Lck in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,680 | Knockout | Lck | protein/peptide distribution | myoblast cell line | Gene: Lck (lymphocyte protein tyrosine kinase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: B cell receptor signaling pathway, CD27 signaling pathway, Fc-gamma receptor signaling pathway, T cell activation, T cell differentiation, T cell receptor signaling pathway, cel... |
Does Knockout of Polr3g in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 1,274 | Knockout | Polr3g | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Polr3g (polymerase (RNA) III (DNA directed) polypeptide G)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell population proliferation, defense response to virus, epithelial cell proliferation, immune system process, innate immune response, positive regulation of ... |
Does Knockout of Ophn1 in Mouse cell causally result in protein/peptide accumulation? | 0 | 1,047 | Knockout | Ophn1 | protein/peptide accumulation | Mouse cell | Gene: Ophn1 (oligophrenin 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: actin cytoskeleton organization, cell junction assembly, cell morphogenesis involved in neuron differentiation, cerebellar granule cell differentiation, cerebral cortex neuron differentiation, en... |
Does Knockout of Nradd in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,284 | Knockout | Nradd | cell proliferation | Mouse kidney carcinoma cell | Gene: Nradd (neurotrophin receptor associated death domain)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Rho protein signal transduction, apoptotic process, signal transduction; MF: coreceptor activity, death receptor activity, nerve growth factor binding, neurotrophin... |
Does Knockout of Slc40a1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity? | 0 | 2,171 | Knockout | Slc40a1 | tumorigenicity | Breast Adenocarcinoma Cell Line | Gene: Slc40a1 (solute carrier family 40 (iron-regulated transporter), member 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: endothelium development, establishment of localization in cell, intracellular iron ion homeostasis, iron ion export across plasma membrane, iron... |
Does Knockout of Ifna16 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Ifna16 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Ifna16 (interferon alpha 16)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: B cell activation involved in immune response, T cell activation involved in immune response, adaptive immune response, defense response, defense response to virus, humoral immune response,... |
Does Knockout of Satb1 in Microglial Cell Line causally result in protein/peptide accumulation? | 0 | 1,398 | Knockout | Satb1 | protein/peptide accumulation | Microglial Cell Line | Gene: Satb1 (special AT-rich sequence binding protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CD4-positive, alpha-beta T cell differentiation, CD8-positive, alpha-beta T cell differentiation, T cell activation, activated T cell proliferation, chromatin organiza... |
Does Knockout of Prss44 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,277 | Knockout | Prss44 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Prss44 (serine protease 44)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: germ cell development, proteolysis, spermatogenesis; MF: hydrolase activity, peptidase activity, serine-type endopeptidase activity, serine-type peptidase activity; CC: cytoplasm, extracellu... |
Does Knockout of Il4 in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 579 | Knockout | Il4 | cell proliferation | Embryonic Stem Cell Line | Gene: Il4 (interleukin 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: B cell activation, B cell costimulation, T cell activation, T-helper 1 cell lineage commitment, T-helper 2 cell differentiation, autophagy, cell surface receptor signaling pathway via JAK-STAT, chol... |
Does Knockout of Mettl22 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,284 | Knockout | Mettl22 | cell proliferation | Mouse kidney carcinoma cell | Gene: Mettl22 (methyltransferase 22, Kin17 lysine)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: heat shock protein binding, methyltransferase activity, protein methyltransferase activity, protein-lysine N-methyltransferase activity, transferase activity; CC: nucleolus,... |
Does Knockout of Slc4a4 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 165 | Knockout | Slc4a4 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Slc4a4 (solute carrier family 4 (anion exchanger), member 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: bicarbonate transport, establishment of localization in cell, inorganic anion transport, monoatomic anion transmembrane transport, monoatomic anion transport... |
Does Knockout of Trap1a in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 688 | Knockout | Trap1a | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Trap1a (tumor rejection antigen P1A)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: P19473
Entrez ID: 22037 |
Does Knockout of Foxo6 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 2,403 | Knockout | Foxo6 | protein/peptide accumulation | Embryonic Cell Line | Gene: Foxo6 (forkhead box O6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: memory, positive regulation of dendritic spine development, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcriptio... |
Does Knockout of Mrgprb2 in pro-B-lymphocyte causally result in response to chemicals? | 0 | 1,720 | Knockout | Mrgprb2 | response to chemicals | pro-B-lymphocyte | Gene: Mrgprb2 (MAS-related GPR, member B2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, mast cell activation, mast cell degranulation, positive regulation of chemokine production, positive regulation of cytokine production,... |
Does Knockout of Ddx42 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 2,170 | Knockout | Ddx42 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Ddx42 (DEAD box helicase 42)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: U2-type prespliceosome assembly, intracellular protein localization, regulation of apoptotic process; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase ... |
Does Knockout of Sec14l4 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 2,170 | Knockout | Sec14l4 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Sec14l4 (SEC14-like lipid binding 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: lipid binding, molecular_function
Pathways:
UniProt: Q8R0F9
Entrez ID: 103655 |
Does Knockout of Cops7a in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 167 | Knockout | Cops7a | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Cops7a (COP9 signalosome subunit 7A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: COP9 signalosome assembly, protein deneddylation; CC: COP9 signalosome, cytoplasm, cytosol, nucleoplasm, nucleus
Pathways: Cargo recognition for clathrin-mediated endocytos... |
Does Knockout of Gm14393 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation? | 0 | 1,077 | Knockout | Gm14393 | protein/peptide accumulation | Mouse Embryonic Stem Cell | Gene: Gm14393 (predicted gene 14393)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways: Herpes simplex virus 1 infection - Mus musculus (mouse)
UniProt: A2ARV8, A2ARW5
Entrez ID: 664987 |
Does Knockout of Capn5 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 167 | Knockout | Capn5 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Capn5 (calpain 5)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the calpain family of proteins. Unlike many members of the calpain gene family, this gene lacks a calmodulin-like domain, required for calcium binding. Mouse models for Huntington's disease displayed in... |
Does Knockout of Stk38l in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 688 | Knockout | Stk38l | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Stk38l (serine/threonine kinase 38 like)
Type: protein-coding
Summary: Predicted to enable ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in regulation of cellular component organization. Located in actin cytoskeleton and cytoplasm. Ort... |
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